Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_050587346.1	9	KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050579505.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050582115.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050576745.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050580649.1	5	MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661	"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050597198.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050578954.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_050574541.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050573952.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050588005.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4551638	"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins"
XP_050594119.1	5	MetaCyc: PWY-7919;Reactome: R-HSA-532668;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106	"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis"
XP_050589419.1	9	KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.25;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_050584264.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050596594.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050600740.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050587910.1	17	MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Pyruvate metabolism"
XP_050579894.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050573129.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050594680.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050594242.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050573163.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-381676	"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_050575971.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050582718.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050578458.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050579070.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050591869.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553	"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"UCH proteinases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs"
XP_050577017.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_050586468.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050581418.1	18	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050583873.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050598880.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050593597.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050592853.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050579310.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_050574523.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-9031525	"Antigen processing: Ubiquitination & Proteasome degradation";"VLDLR internalisation and degradation";"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake"
XP_050576454.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050577358.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050580085.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_050595346.1	7	MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_050585958.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050583794.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050587387.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050585351.1	42	Reactome: R-HSA-9616222;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886;Reactome: R-HSA-2559582;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-110330;Reactome: R-HSA-212300;Reactome: R-HSA-171306;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-9609690;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-5693571;Reactome: R-HSA-8939236;Reactome: R-HSA-3214858;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-427389;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-427413;Reactome: R-HSA-1221632;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-977225	"Transcriptional regulation of granulopoiesis";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Senescence-Associated Secretory Phenotype (SASP)";"DNA methylation";"Cleavage of the damaged pyrimidine";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"PRC2 methylates histones and DNA";"Packaging Of Telomere Ends";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Early Events";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RMTs methylate histone arginines";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"NoRC negatively regulates rRNA expression";"Meiotic synapsis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"Amyloid fiber formation"
XP_050592712.1	7	Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Cristae formation";"Mitochondrial protein import"
XP_050584611.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050597607.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050586955.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050596566.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050592763.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050593403.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050591708.1	4	MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895	"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism"
XP_050574260.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport"
XP_050585860.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050590435.1	10	MetaCyc: PWY-5895;MetaCyc: PWY-5891;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5844;MetaCyc: PWY-5890	"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-10 biosynthesis"
XP_050590507.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050573580.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_050579869.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050600410.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050593566.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695	"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Neutrophil degranulation"
XP_050593599.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050600894.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170670	"Hedgehog 'off' state";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase inhibitory pathway"
XP_050573135.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050582964.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050590644.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-532668;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258	"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL"
XP_050596995.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050578092.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050581792.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-6803207	"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_050573682.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-438066	"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ion homeostasis";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_050581815.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050596866.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050580278.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_050592022.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050588883.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_050587647.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050578237.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050576022.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_050592456.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050576571.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050592051.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050600363.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050579080.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050600495.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050591438.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050593708.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050593032.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050596231.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050589531.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050600745.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050577535.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050594560.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050576208.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050593235.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050577296.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050592031.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050597249.1	12	KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343	"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycogen synthesis";"Sucrose biosynthesis II";"Galactose metabolism";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I"
XP_050589043.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050582472.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050599998.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050597839.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050584513.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050582000.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050573501.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050591783.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050589962.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050599076.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568	"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase"
XP_050594041.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050578823.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050587573.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-1362300;Reactome: R-HSA-69231	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1"
XP_050598594.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050591620.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050582005.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050591388.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_050586971.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050584471.1	6	Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_050594350.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050600885.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660	"PKA activation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway"
XP_050580082.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050579591.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050576207.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050596488.1	9	Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68962	"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex"
XP_050585077.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050589841.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050590892.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_050593863.1	6	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_050595280.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050585659.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_050596725.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050582247.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050577691.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756	"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Synthesis of PC";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation"
XP_050578079.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050582233.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69166	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate"
XP_050576677.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050590862.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_050576058.1	12	Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-166208	"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"mTORC1-mediated signalling"
XP_050573960.1	8	KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-3581;MetaCyc: PWY-5394;Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00350+1.14.16.2	"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis I";"Betalamic acid biosynthesis";"Catecholamine biosynthesis";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"Tyrosine metabolism"
XP_050580287.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050581245.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050596583.1	14	MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_050586214.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050595858.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Chylomicron clearance";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"LDL remodeling";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Platelet sensitization by LDL";"VLDL clearance";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Scavenging by Class B Receptors"
XP_050587425.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis"
XP_050593392.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050592924.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050573795.1	15	KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-1042	"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis";"Glycerol degradation to butanol";"Rubisco shunt";"Glycolysis IV (plant cytosol)"
XP_050578281.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050577469.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167290	"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation"
XP_050576134.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050597006.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050573340.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050574630.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050590100.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050591988.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050590447.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050593487.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050589059.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_050591626.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050599911.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050598879.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_050580767.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050600714.1	11	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_050595553.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050579878.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050594496.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050586170.1	7	KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2	"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism"
XP_050573702.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050573876.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_050586908.1	7	MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456	"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylketonuria"
XP_050582307.1	4	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-1268020	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial protein import"
XP_050584279.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050588292.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_050575036.1	13	KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5	"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism"
XP_050585949.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050587170.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_050597555.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050586753.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050594870.1	5	KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_050586656.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050595802.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050594982.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050595109.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050599212.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050588781.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050576669.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_050591651.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050600757.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050587991.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_050574103.1	9	Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-2173791;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer"
XP_050588220.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919	"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils"
XP_050583113.1	24	Reactome: R-HSA-9634600;Reactome: R-HSA-381676;Reactome: R-HSA-8853659;Reactome: R-HSA-432040;Reactome: R-HSA-5621575;Reactome: R-HSA-5687128;Reactome: R-HSA-8963896;Reactome: R-HSA-163358;Reactome: R-HSA-111931;Reactome: R-HSA-163615;Reactome: R-HSA-9010642;Reactome: R-HSA-180024;Reactome: R-HSA-4420097;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-442720;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-422356;KEGG: 04150+2.7.11.11;Reactome: R-HSA-392517;Reactome: R-HSA-163560;Reactome: R-HSA-983231	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"RET signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"CD209 (DC-SIGN) signaling";"MAPK6/MAPK4 signaling";"HDL assembly";"PKA-mediated phosphorylation of key metabolic factors";"PKA-mediated phosphorylation of CREB";"PKA activation";"ROBO receptors bind AKAP5";"DARPP-32 events";"VEGFA-VEGFR2 Pathway";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Regulation of insulin secretion";"mTOR signaling pathway";"Rap1 signalling";"Triglyceride catabolism";"Factors involved in megakaryocyte development and platelet production"
XP_050585868.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050598765.1	7	KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;MetaCyc: PWY-5188;Reactome: R-HSA-6782315	"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol"
XP_050597140.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050588454.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050584474.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6"
XP_050580497.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050577664.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-189451	"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis"
XP_050592311.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050583915.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050574108.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050599222.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3899300	"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors"
XP_050591977.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050588028.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050597468.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050589655.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_050578172.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050576192.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050581016.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050576792.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050579326.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy"
XP_050573206.1	5	Reactome: R-HSA-111457;Reactome: R-HSA-111469;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111463	"Release of apoptotic factors from the mitochondria";"SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs"
XP_050577504.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_050585134.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050583388.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050578688.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001	"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050595685.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_050589302.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050593039.1	10	Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880	"HATs acetylate histones";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"Ub-specific processing proteases"
XP_050589589.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050593565.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695	"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation"
XP_050597964.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050590028.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050592593.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050593442.1	7	MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5686	"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis I"
XP_050576164.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050594366.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050591980.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050593034.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050599440.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2644606	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050589035.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050581573.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050575027.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050590924.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050597686.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050585182.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_050582854.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050583050.1	5	MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560	"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
XP_050600228.1	1	Reactome: R-HSA-500753	"Pyrimidine biosynthesis"
XP_050593642.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061	"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification I"
XP_050592121.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050580679.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050589951.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_050575123.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050592821.1	5	Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
XP_050586940.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050592134.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050591257.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050592087.1	8	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050598549.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_050588916.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050586470.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050578168.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050597752.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050584601.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050577857.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050600433.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050575350.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050576650.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_050597591.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050577736.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050585010.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050576014.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050590799.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050581536.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050593937.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050592786.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050578063.1	18	KEGG: 00950+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6642;MetaCyc: PWY-7383	"Isoquinoline alkaloid biosynthesis";"Arginine and proline metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050594725.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_050582814.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050596723.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050596550.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050600878.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050596036.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_050594338.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050586841.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050585011.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_050594801.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050575758.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050573886.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050596862.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050579304.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050583844.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050573336.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050577919.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050592711.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050582306.1	4	Reactome: R-HSA-5368286;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050593631.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050582114.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050574624.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050582831.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050580639.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050595212.1	6	MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050579935.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050574467.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050598301.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050580904.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050576903.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_050591991.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050598526.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050581226.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_050596570.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050595085.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050577764.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050581218.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050584715.1	56	Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590	"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling"
XP_050594946.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_050578575.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050595755.1	18	MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_050589308.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050596186.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_050588329.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050592962.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050597452.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050597424.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050583017.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050597367.1	16	MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-2046105;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-2046106;MetaCyc: PWY-7036;MetaCyc: PWY-5972	"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Linoleic acid (LA) metabolism";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"alpha-linolenic acid (ALA) metabolism";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)"
XP_050600564.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_050599271.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050573879.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_050579426.1	3	KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_050580836.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_050587431.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050580496.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050598349.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_050592379.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050592364.1	13	Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-937072;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-975163	"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
XP_050595808.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050582273.1	13	Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Ca2+ pathway"
XP_050597809.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_050582365.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050576204.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050585928.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050585828.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_050581497.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050583756.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050600137.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050583858.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050599527.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583452.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050578074.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050593486.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050595767.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_050580771.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050585927.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050593799.1	6	KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11	"Glycine, serine and threonine metabolism";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis"
XP_050593576.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050575021.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050589661.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050596658.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050578614.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_050583219.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050593695.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050595571.1	7	MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183	"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050582461.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050586944.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050592392.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050594977.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050573649.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"Long-term potentiation";"Ion homeostasis";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_050579608.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050593578.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050587908.1	17	MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2	"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes"
XP_050589029.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050595081.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050573640.1	5	KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;Reactome: R-HSA-446210	"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine"
XP_050576371.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050581407.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_050589606.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050592298.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050587225.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050595132.1	8	Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724	"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription"
XP_050588302.1	11	Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050587534.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050593377.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050592942.1	15	Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-176034;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246	"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Interactions of Tat with host cellular proteins";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript"
XP_050574448.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050596712.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050598491.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_050585426.1	11	Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_050587906.1	17	KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5789;MetaCyc: PWY-6722	"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis"
XP_050600613.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050585344.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050590645.1	5	KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046;KEGG: 00640+1.2.4.4;Reactome: R-HSA-389661	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050580790.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050592865.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050593545.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952	"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions"
XP_050583059.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050575972.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050586780.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_050595572.1	7	MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702	"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I"
XP_050589623.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_050581720.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050594923.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050589223.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050595214.1	6	MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952	"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_050581405.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis"
XP_050586802.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360	"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_050580919.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050578800.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050598758.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_050589357.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050600389.1	12	KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;MetaCyc: PWY-6932	"Purine metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Purine metabolism";"Sulfur metabolism";"Transport and synthesis of PAPS";"Sulfur metabolism";"Sulfate activation for sulfonation";"Selenate reduction"
XP_050593548.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946	"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants"
XP_050582841.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050582312.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-2586552	"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Signaling by Leptin"
XP_050578122.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050593135.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050577510.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050597413.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
XP_050586311.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050593136.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050576267.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050597485.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050576331.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050585104.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050594854.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050586987.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050592396.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050588627.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050585525.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050582149.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_050600767.1	7	Reactome: R-HSA-983231;Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-8943724	"Factors involved in megakaryocyte development and platelet production";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription"
XP_050575348.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050600568.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050574372.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050590646.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_050577855.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050581566.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"Syndecan interactions";"Molecules associated with elastic fibres";"ECM proteoglycans"
XP_050589056.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050598969.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050581677.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050592054.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050578096.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050575854.1	5	KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006	"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_050597219.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050583816.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050585725.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050578358.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050596724.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050584672.1	6	Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_050574678.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050590254.1	6	Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_050576269.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050598108.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050578044.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050592282.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050591189.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050577480.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_050582626.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050586273.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050591692.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050586248.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050576960.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050586463.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_050596068.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050577222.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050596001.1	17	MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_050578028.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050574764.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050590033.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_050578828.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050580903.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050588875.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050598255.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050599321.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050576458.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_050584615.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050590896.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050598396.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_050582829.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050575616.1	6	MetaCyc: PWY-7395;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-7077;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25	"D-galactosamine and N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_050589533.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050596737.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050595669.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_050589277.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050588626.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050589049.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050589476.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050599426.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_050587538.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050581756.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050598291.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050595894.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050582396.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_050586821.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050593453.1	7	MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686	"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050575322.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050591028.1	5	Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20	"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism"
XP_050588323.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050592032.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050582973.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050598490.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050573653.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_050588142.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050590466.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_050587542.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050581209.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050585920.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050573862.1	8	Reactome: R-HSA-209905;MetaCyc: PWY-3581;MetaCyc: PWY-5049;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2	"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I";"Rosmarinic acid biosynthesis II";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"(S)-reticuline biosynthesis II";"Folate biosynthesis"
XP_050573730.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050574571.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050595385.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050598866.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8	"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_050599073.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3899300	"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors"
XP_050577905.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_050582751.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050578085.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;MetaCyc: PWY-7511	"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Protein ubiquitination"
XP_050594100.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050580728.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050577634.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050584484.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050592528.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050599778.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050588596.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050581750.1	7	Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-375276;Reactome: R-HSA-381426;Reactome: R-HSA-416476;Reactome: R-HSA-140837;Reactome: R-HSA-418594	"Platelet degranulation";"Post-translational protein phosphorylation";"Peptide ligand-binding receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (i) signalling events"
XP_050579594.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050579216.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050591373.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_050597796.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050592360.1	13	Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-975163	"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
XP_050586914.1	3	Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB"
XP_050590801.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050584832.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050583200.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_050577361.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050577309.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050573979.1	9	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection"
XP_050593809.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_050584645.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050574646.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_050592126.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050583946.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050589600.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050598480.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050593666.1	13	KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1	"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism"
XP_050573967.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050595031.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050600623.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050584621.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050589417.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_050585880.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050588868.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_050577920.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050576644.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050579284.1	17	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol"
XP_050597564.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050583857.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050595776.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_050579897.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050581636.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050595352.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469	"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis"
XP_050587972.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978	"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_050575388.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_050583014.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050596193.1	7	MetaCyc: PWY-31;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-4984;Reactome: R-HSA-70635	"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Urea cycle";"Urea cycle"
XP_050597254.1	12	MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9	"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Galactose metabolism";"Sucrose biosynthesis II";"Glycogen synthesis";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism"
XP_050589039.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050598385.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_050578830.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050598777.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050600434.1	10	KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11	"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism"
XP_050590711.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-9645722;Reactome: R-HSA-140837	"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation"
XP_050586941.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050589974.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050578378.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050577279.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_050588145.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050599394.1	16	Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571	"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"HATs acetylate histones";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)"
XP_050587085.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050596351.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050585558.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050577247.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050582706.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050579874.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050581775.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050592757.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_050597218.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050574483.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_050596951.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-1632852	"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy"
XP_050580479.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050587256.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_050594444.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050590011.1	8	Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis"
XP_050587348.1	9	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050588530.1	5	Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_050590519.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050598012.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050575289.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050585290.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050579226.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050586389.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389	"Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases"
XP_050580680.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050577806.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050580365.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050598567.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050595030.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050587191.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050583806.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598896.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050577598.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events"
XP_050597684.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050575756.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_050583814.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050597148.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050592589.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050589466.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_050580144.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050597922.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050586109.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050595546.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050589293.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050599308.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050577663.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;Reactome: R-HSA-6798695	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation"
XP_050591705.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050580124.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050587254.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_050581779.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050573884.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050577572.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_050581031.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050598856.1	11	Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-3881	"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Mannitol degradation II";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis"
XP_050596881.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_050577683.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism"
XP_050580786.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050583441.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050594115.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174178	"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_050590012.1	8	Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7979	"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)"
XP_050589780.1	5	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway"
XP_050583723.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050578870.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050573951.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050585345.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050587576.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1362300;Reactome: R-HSA-69231	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1"
XP_050576304.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662	"Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism"
XP_050575130.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050593244.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050598186.1	10	Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6365;Reactome: R-HSA-983231;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.134+2.7.1.159;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6362;Reactome: R-HSA-1855204;MetaCyc: PWY-6366	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"
XP_050583043.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050578994.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050587951.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050573502.1	18	MetaCyc: PWY-6969;Reactome: R-HSA-70263;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-7383	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050574948.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050579817.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050573679.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-3371571	"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"HSF1-dependent transactivation"
XP_050598807.1	3	KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_050600501.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050589881.1	4	MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_050581814.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050595322.1	4	KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50	"Arginine and proline metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_050575022.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050579172.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050594101.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050596423.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050578003.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_050581333.1	7	KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882	"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_050578036.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050578372.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050597083.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050578576.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050598515.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_050586215.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050596602.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050575031.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050578071.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_050592024.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050587459.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050573722.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_050596807.1	6	Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118	"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle"
XP_050598300.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050591005.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050591156.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050583738.1	8	KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7524	"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Mevalonate pathway III (archaea)"
XP_050583024.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050577341.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661	"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation"
XP_050589414.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050588056.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy"
XP_050597455.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050588915.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050592038.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050592262.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050583904.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050595455.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050579517.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050599485.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050591900.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050579373.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_050580809.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050586023.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-72203	"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050596314.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050589882.1	4	MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_050575386.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050584179.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050586098.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050581251.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681	"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT"
XP_050592893.1	10	Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-5689880	"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Ub-specific processing proteases"
XP_050577066.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_050573600.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050579778.1	18	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050578351.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050587817.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604	"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling"
XP_050585474.1	5	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050580438.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050596922.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050588933.1	3	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_050586373.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050593810.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
XP_050595244.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148	"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Aggrephagy";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050599444.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575	"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling"
XP_050584140.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050589170.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_050591701.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050581413.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis"
XP_050582421.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050580374.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050593384.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050587567.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_050593962.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050592383.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050576774.1	7	KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661	"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_050583450.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050578374.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050595107.1	7	Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67	"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism"
XP_050578973.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050596388.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050597711.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050581710.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"Neutrophil degranulation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050581357.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050573384.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050581541.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050586843.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050598091.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050580282.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_050584347.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050582958.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050585948.1	6	Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis";"Mitochondrial protein import";"Cristae formation"
XP_050584450.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050588158.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_050597294.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050600329.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_050590558.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050591752.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050590807.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050577574.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_050586658.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050600132.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050593592.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-109704	"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade"
XP_050595538.1	15	Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-111465	"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins"
XP_050578216.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050579969.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050582842.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_050600001.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050580888.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_050578539.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-73863	"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination"
XP_050583845.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050595087.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050589975.1	19	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-983231;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8950505	"RHO GTPases Activate Formins";"Myogenesis";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"Factors involved in megakaryocyte development and platelet production";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050574300.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050581228.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050574291.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050584485.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050579062.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050592933.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050593965.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050592543.1	9	MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883	"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II"
XP_050583273.1	3	Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050574334.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050594644.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050574655.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_050585178.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050597235.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050587192.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050575900.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050585360.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050578956.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37	"DNA methylation";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism"
XP_050574549.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050574348.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050586473.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050590550.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050573338.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_050600562.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050592604.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050578227.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050587876.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050588629.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050580123.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050589370.1	12	MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism"
XP_050591364.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_050576338.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050581189.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050590479.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050595111.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-6922;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism"
XP_050579818.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050579169.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050587969.1	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
XP_050600111.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_050592453.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050583436.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050577631.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050583148.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050598529.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050600951.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050582392.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050581722.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050582315.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050600604.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050576198.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050594525.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050590955.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050594573.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050578657.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6798695	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation"
XP_050581660.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-191859	"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"snRNP Assembly"
XP_050600673.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050579224.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050580948.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050575341.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050592830.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_050598395.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_050575305.1	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_050586195.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050585941.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_050585428.1	11	Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482	"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050592941.1	15	Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-75955;Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243	"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Transcription Elongation";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery"
XP_050577109.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_050589359.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050590829.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050581880.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050575628.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050581417.1	18	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050600140.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050592474.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050591871.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050581188.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050598784.1	11	Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-912694;Reactome: R-HSA-432142;Reactome: R-HSA-114604;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-389948;Reactome: R-HSA-877312	"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"Regulation of IFNA signaling";"Platelet sensitization by LDL";"GPVI-mediated activation cascade";"Signal regulatory protein family interactions";"PECAM1 interactions";"Interleukin-37 signaling";"PD-1 signaling";"Regulation of IFNG signaling"
XP_050584015.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050588914.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_050594458.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619	"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN"
XP_050600068.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050587227.1	15	Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939	"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)"
XP_050600085.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050592454.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050599613.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050587401.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362300	"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050588338.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050593956.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050574769.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050581235.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050584628.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050600485.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome"
XP_050590927.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050600101.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050576083.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_050579690.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050582221.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050598211.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050574391.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_050590684.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_050591285.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_050581412.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_050589149.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation"
XP_050590404.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050598495.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050589048.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_050578838.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050587090.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050577573.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_050575303.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_050597028.1	6	MetaCyc: PWY-622;Reactome: R-HSA-3322077;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067	"Starch biosynthesis";"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_050599897.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050577320.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_050580403.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_050595005.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050597554.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050596074.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_050594377.1	11	Reactome: R-HSA-2029485;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4	"Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism"
XP_050595573.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I"
XP_050597252.1	12	KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9	"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Glycerolipid metabolism"
XP_050575905.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050583188.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050598357.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050574042.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_050596482.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411	"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere"
XP_050578577.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050590446.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050	"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_050575643.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050577570.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_050593448.1	7	KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686	"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050592029.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050596814.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050594868.1	5	KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)"
XP_050573303.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Signaling by Hippo";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_050594099.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050587702.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050587699.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050598916.1	19	MetaCyc: PWY-7220;MetaCyc: PWY-7176;Reactome: R-HSA-380320;MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7210;Reactome: R-HSA-380270;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6	"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Pyrimidine metabolism"
XP_050597505.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050575641.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-2151209	"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_050588908.1	3	MetaCyc: PWY-7158;MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96	"L-phenylalanine degradation V";"Tetrahydropteridine recycling";"Folate biosynthesis"
XP_050592951.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050579744.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050578094.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050587059.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050599953.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050587877.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_050587202.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050589155.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_050598119.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050581437.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050585798.1	6	KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123;Reactome: R-HSA-73817	"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
XP_050577528.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050599309.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050582617.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_050590204.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_050581003.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_050580097.1	33	Reactome: R-HSA-4551638;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025	"SUMOylation of chromatin organization proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation"
XP_050592388.1	6	MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-196780	"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Biotin transport and metabolism"
XP_050586681.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050577451.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050591968.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050591904.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050582897.1	11	Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580	"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"mTOR signaling pathway";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence"
XP_050580206.1	7	Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-180746	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein"
XP_050592389.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050586911.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050594103.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050579968.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050574527.1	7	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-166208	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"mTORC1-mediated signalling"
XP_050592745.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_050588523.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050589452.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178	"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans"
XP_050591162.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_050600595.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050596079.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_050591256.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050583971.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050588663.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_050590423.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050580816.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-180910	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs"
XP_050573812.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050592337.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_050599287.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050580404.1	2	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_050593402.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_050576443.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050578747.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050599681.1	26	Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-201722	"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex"
XP_050598399.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation"
XP_050577223.1	3	Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12	"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism"
XP_050595071.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050587995.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_050581642.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050597268.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050581247.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050581506.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050593046.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_050579196.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050578160.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex"
XP_050597588.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050600056.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050586666.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050573021.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050584835.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050591813.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050594439.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050579381.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050584658.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050575679.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050595529.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050576444.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050585311.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_050577476.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050583854.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050580975.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050574374.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050593231.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050582006.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050573114.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_050584583.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050589757.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050575897.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598963.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050580284.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Regulation of PTEN localization"
XP_050584673.1	6	MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia"
XP_050584635.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_050580483.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050594207.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050593447.1	7	MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686	"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050577491.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050580015.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050591693.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050592267.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050582147.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_050594406.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050596148.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-1989781	"Phase I - Functionalization of compounds";"Xenobiotics";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"PPARA activates gene expression"
XP_050588452.1	5	Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148	"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050600636.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050582593.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050590514.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050577982.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050573157.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050578492.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050579214.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050575515.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050597146.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050573885.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050574631.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050595236.1	4	KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050598582.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_050575932.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050584607.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050592128.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050577933.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050586657.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050589886.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050592395.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050589118.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050584834.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050600467.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050595098.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050597143.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_050599818.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050578380.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050580079.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050597828.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050573234.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050579477.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050593685.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050596543.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050583862.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050578824.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050584586.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050588065.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050585013.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_050596151.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_050578470.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050591616.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050586162.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050598384.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_050587294.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050579018.1	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_050580575.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050587452.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050584592.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050580684.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050595917.1	7	Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187	"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress"
XP_050587954.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050598030.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050599146.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"PKA activation"
XP_050586199.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_050591787.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050574245.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050600614.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050580339.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050584846.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050573661.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050584472.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050598072.1	4	KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_050574107.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050582257.1	24	Reactome: R-HSA-444257;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;Reactome: R-HSA-2871837;Reactome: R-HSA-354192;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2730905	"RSK activation";"Regulation of TP53 Degradation";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"Human cytomegalovirus infection";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"FCERI mediated NF-kB activation";"Integrin signaling";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"Activation of AKT2";"PIP3 activates AKT signaling";"Downstream TCR signaling";"Human papillomavirus infection";"Thermogenesis";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Role of LAT2/NTAL/LAB on calcium mobilization"
XP_050575306.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050580726.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050595390.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050599573.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050595441.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097	"p38MAPK events";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway"
XP_050597895.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050588804.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_050593936.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050584975.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050595126.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050583666.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050578335.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838	"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO"
XP_050600003.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050573747.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen degradation";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures"
XP_050585772.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_050586934.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050582836.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050592462.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050596342.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_050575857.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211	"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"ESR-mediated signaling"
XP_050593040.1	17	Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607	"Fanconi Anemia Pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"Meiotic synapsis";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends"
XP_050594253.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II"
XP_050583811.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050581069.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050600727.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050585179.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050596009.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050595507.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050592452.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050576953.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050587330.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1"
XP_050587422.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_050586258.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050581724.1	56	Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-8951664	"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neddylation"
XP_050587889.1	3	Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271	"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_050584651.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050596045.1	5	MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2"
XP_050581790.1	8	Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-9627069	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity"
XP_050592598.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050586596.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050584127.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050600556.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050578037.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_050579977.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050590136.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050589464.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_050595475.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_050573551.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050596219.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050596997.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050577744.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050577404.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050591855.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_050580770.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050573197.1	22	MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-7601;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7053;MetaCyc: PWY-6598;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7727;MetaCyc: PWY-6433	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050579303.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050586851.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050585094.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050586962.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050598520.1	14	Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_050573088.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050575965.1	12	Reactome: R-HSA-70263;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13	"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis"
XP_050578451.1	5	MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_050578035.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050574271.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050594893.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050583446.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050573775.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050573368.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA"
XP_050597622.1	6	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;Reactome: R-HSA-1660517;KEGG: 00562+3.1.3.64	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism"
XP_050585404.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050580971.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050586570.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_050583352.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050594413.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050584981.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050576057.1	12	Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-9010553	"Translation initiation complex formation";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs"
XP_050577339.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050592526.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
XP_050583931.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_050585196.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050586071.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050583025.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050590790.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_050584052.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050593700.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050574397.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_050599648.1	4	Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_050595912.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050587666.1	5	KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism";"Stachyose degradation"
XP_050589787.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050592157.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050589384.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050591507.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_050598774.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050600020.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050576183.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050583082.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050573089.1	5	Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_050575451.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050593443.1	7	MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790	"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis II"
XP_050600600.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050582010.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050590385.1	17	Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-4086398;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-9020702	"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"Ca2+ pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling"
XP_050595804.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050589767.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_050593206.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050599281.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050574359.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050592657.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_050592152.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050598351.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_050576652.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_050598877.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;KEGG: 00520+5.3.1.8;MetaCyc: PWY-6992;MetaCyc: PWY-882	"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Mannitol degradation II";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_050582812.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050594866.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050582788.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050593355.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050580299.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050579022.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050587549.1	5	MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121	"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_050597553.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050597982.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050588784.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050585556.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050587958.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_050591030.1	5	Reactome: R-HSA-75109;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20	"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis"
XP_050578871.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050580828.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050573701.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050596578.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050588443.1	9	KEGG: 00270+2.6.1.5;KEGG: 00950+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00130+2.6.1.5	"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_050583019.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050575299.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050593667.1	13	MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism"
XP_050598002.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_050592895.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_050589182.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583769.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583425.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050579362.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_050586859.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050597965.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050596451.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436	"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Kinesins";"MHC class II antigen presentation";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050587473.1	4	Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-176187	"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Activation of ATR in response to replication stress"
XP_050588917.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_050594151.1	4	KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis"
XP_050576636.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4"
XP_050590000.1	52	Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176	"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Separation of Sister Chromatids";"ER-Phagosome pathway";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Degradation of AXIN";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_050585398.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050577823.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050590824.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050588836.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation"
XP_050588958.1	13	MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2022857	"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"CS/DS degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Keratan sulfate degradation"
XP_050574281.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050580472.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050588573.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050591446.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_050582575.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050575627.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050592940.1	15	Reactome: R-HSA-176034;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152	"Interactions of Tat with host cellular proteins";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_050587429.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050586677.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050573173.1	17	Reactome: R-HSA-6798695;MetaCyc: PWY-6627;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6608;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6620;MetaCyc: PWY-4202;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1	"Neutrophil degranulation";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Purine metabolism"
XP_050593132.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I"
XP_050600110.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050599323.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050580101.1	33	Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-191859	"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of RNA binding proteins";"snRNP Assembly"
XP_050574762.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050577591.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050600504.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050595620.1	11	Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-72163	"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway"
XP_050599563.1	8	MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5789	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_050579155.1	7	MetaCyc: PWY-6121;Reactome: R-HSA-196780;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13	"5-aminoimidazole ribonucleotide biosynthesis I";"Biotin transport and metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism"
XP_050589134.1	6	Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_050593865.1	6	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427359	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression"
XP_050594865.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050591955.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050573650.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050578537.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-611105	"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport"
XP_050588659.1	12	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_050599574.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050578494.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050584916.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050580912.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050594260.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050580727.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050577533.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050600185.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050597001.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050595929.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050576056.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-166208	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"mTORC1-mediated signalling"
XP_050593469.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050583579.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050574924.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050574843.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050594861.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050595083.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050581937.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050581489.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050589594.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050595545.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050575474.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050581764.1	24	Reactome: R-HSA-1257604;Reactome: R-HSA-202424;Reactome: R-HSA-165158;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;Reactome: R-HSA-5625740;Reactome: R-HSA-5674400;Reactome: R-HSA-9634635;Reactome: R-HSA-389357;Reactome: R-HSA-392451	"PIP3 activates AKT signaling";"Downstream TCR signaling";"Activation of AKT2";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"Thermogenesis";"Human papillomavirus infection";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"RSK activation";"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs";"Constitutive Signaling by AKT1 E17K in Cancer";"Estrogen-stimulated signaling through PRKCZ";"CD28 dependent PI3K/Akt signaling";"G beta:gamma signalling through PI3Kgamma"
XP_050596343.1	6	Reactome: R-HSA-390247;Reactome: R-HSA-1369062;Reactome: R-HSA-5684045;Reactome: R-HSA-2046105;Reactome: R-HSA-9603798;Reactome: R-HSA-2046106	"Beta-oxidation of very long chain fatty acids";"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Linoleic acid (LA) metabolism";"Class I peroxisomal membrane protein import";"alpha-linolenic acid (ALA) metabolism"
XP_050596921.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_050573345.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050584957.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050592037.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050588035.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_050599623.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050579991.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_050599310.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050589098.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_050595392.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050583155.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050579781.1	18	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_050585909.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050600672.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050582972.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050593383.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_050576839.1	10	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050578126.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_050581138.1	14	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167242	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_050580105.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050586316.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_050593045.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_050580303.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_050580118.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050584977.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050597472.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050589374.1	12	MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism"
XP_050599221.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508	"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_050585017.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050584976.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050576320.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050577300.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050596726.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050577983.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_050579872.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050580076.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050591252.1	16	Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-164939;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-177504	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling"
XP_050589169.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080	"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I"
XP_050581145.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167200	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050576019.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050576501.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050587086.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050577798.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-350054	"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway"
XP_050591833.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050586912.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050592811.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206296;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS II - Hunter syndrome";"HS-GAG degradation"
XP_050583439.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050582962.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050596226.1	5	KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1;MetaCyc: PWY-6012;Reactome: R-HSA-199220;MetaCyc: PWY-6289	"Pantothenate and CoA biosynthesis";"Acyl carrier protein activation";"Acyl carrier protein metabolism";"Vitamin B5 (pantothenate) metabolism";"Petrobactin biosynthesis"
XP_050583745.1	8	KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-922	"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I"
XP_050591429.1	4	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5656169	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis"
XP_050595101.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050581285.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050584627.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050583808.1	5	KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069	"Cysteine and methionine metabolism";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Regulation of the apoptosome activity"
XP_050592052.1	7	KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-7234	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III"
XP_050599414.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050582366.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050587681.1	7	Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism"
XP_050584965.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050582022.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050592028.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050596030.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_050582072.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050584707.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_050574044.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050594206.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050586950.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050596923.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050584908.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_050598717.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050596880.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050595315.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050580132.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050597603.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050586383.1	10	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation"
XP_050598713.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050588308.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane"
XP_050587952.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050592557.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050581030.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050598373.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_050583009.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050597475.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050597091.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050586967.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050584580.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050594215.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050587029.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050590399.1	57	Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-211733	"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"UCH proteinases";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_050592040.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050589467.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050595665.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050597677.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_050586826.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050577266.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050599282.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050596146.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211976	"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Endogenous sterols"
XP_050573948.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050593124.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050596989.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050598086.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050584125.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-5695;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Purine metabolism"
XP_050593931.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050575452.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050573783.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_050577581.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050577833.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050585651.1	13	KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7883	"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II"
XP_050594752.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050596845.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050591161.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050596551.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050584923.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398	"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway"
XP_050582370.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050586713.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050578412.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050599191.1	26	Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050585681.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050578093.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050596992.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_050595147.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050591790.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050582796.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050583916.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050574729.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050573100.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050595540.1	15	Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716	"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_050590149.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050595220.1	6	Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_050597432.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050586549.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050587041.1	9	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Neddylation"
XP_050588852.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050583385.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050581949.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050592156.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050584584.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050587915.1	17	MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599	"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Carnitine metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Pyruvate metabolism";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency"
XP_050586810.1	7	MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25	"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_050590025.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050591690.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_050580092.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050597024.1	6	MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530	"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II"
XP_050582821.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050585923.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050587641.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050584274.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050576184.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050579219.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050591986.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050585861.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050574363.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050588907.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050581783.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050575687.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050579588.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050582090.1	24	Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-5625740	"Activation of AKT2";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Integrin signaling";"PIP3 activates AKT signaling";"Downstream TCR signaling";"Thermogenesis";"GPVI-mediated activation cascade";"Human papillomavirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"RSK activation";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs"
XP_050580952.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050600711.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050595756.1	18	Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788	"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC"
XP_050587137.1	9	Reactome: R-HSA-112043;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039	"PLC beta mediated events";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_050586655.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050578740.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_050598496.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050573622.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050594533.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050600909.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050581848.1	24	Reactome: R-HSA-392451;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;Reactome: R-HSA-2871837;Reactome: R-HSA-5625740;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-202424;Reactome: R-HSA-1257604	"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs";"RSK activation";"Regulation of TP53 Degradation";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Activation of AKT2";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Downstream TCR signaling";"PIP3 activates AKT signaling"
XP_050592442.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050583739.1	8	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)"
XP_050582151.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050577242.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050586852.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050588388.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050593232.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050581358.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050587398.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_050576389.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis"
XP_050582860.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050594330.1	10	MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;Reactome: R-HSA-1483166	"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA"
XP_050580043.1	4	Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I"
XP_050574201.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050575684.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050596171.1	22	Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050583618.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050594929.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310	"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway"
XP_050590812.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050580723.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050583746.1	8	MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_050592424.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050578082.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050588159.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050588672.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050592229.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050599280.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050586169.1	7	Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2	"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism"
XP_050593554.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"Neutrophil degranulation";"MAP2K and MAPK activation"
XP_050577299.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050592138.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050572992.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_050600119.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050590513.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050583907.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-983168	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050577766.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050583803.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050574817.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050576762.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050589044.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050585106.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050597600.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050591473.1	4	KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221	"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis"
XP_050595408.1	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050582820.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050600571.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050593696.1	3	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_050592765.1	20	Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-174411	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Polymerase switching";"Polymerase switching on the C-strand of the telomere"
XP_050587104.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050579045.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050590907.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_050595309.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050584206.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050587160.1	4	KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_050586664.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050573471.1	8	KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1	"Galactose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis";"Streptomycin biosynthesis"
XP_050577669.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050590083.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050577167.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade"
XP_050597038.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050588143.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050592965.1	17	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050586301.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050579385.1	57	Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424	"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"ER-Phagosome pathway";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"UCH proteinases";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling"
XP_050576368.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693	"RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling"
XP_050593085.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050594156.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2	"Amino acids regulate mTORC1";"Insulin receptor recycling";"Photosynthesis";"ATP biosynthesis";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Oxidative phosphorylation"
XP_050597716.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107	"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_050592358.1	13	Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-937072	"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050597421.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050594772.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050590840.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050583125.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050581238.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050589163.1	14	MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050582696.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050598732.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050590827.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050585381.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050576683.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
XP_050597601.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050587038.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050575490.1	14	Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5104;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00770+2.6.1.42;MetaCyc: PWY-7767;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5108;MetaCyc: PWY-5057	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"L-leucine degradation III";"L-isoleucine biosynthesis IV";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"L-isoleucine degradation II";"Pantothenate and CoA biosynthesis";"L-leucine degradation IV (Stickland reaction)";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis V";"L-valine degradation II"
XP_050588779.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050581409.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_050593743.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050599329.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050600696.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050592285.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050586665.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050595577.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050581229.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050578469.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050579020.1	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_050599077.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-1989781	"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression"
XP_050597289.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050578831.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050582891.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598070.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050588037.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy"
XP_050582968.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050580499.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050573371.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050581022.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050580863.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050590925.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050590844.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050576440.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050581782.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050580758.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050585052.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050573159.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050574214.1	14	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-4086398;Reactome: R-HSA-399997;Reactome: R-HSA-500657;Reactome: R-HSA-434316;Reactome: R-HSA-112043;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-418217	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Ca2+ pathway";"Acetylcholine regulates insulin secretion";"Presynaptic function of Kainate receptors";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"PLC beta mediated events";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G beta:gamma signalling through PLC beta"
XP_050583991.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050585682.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050589973.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050591814.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050582481.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050574346.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050594123.1	5	KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;Reactome: R-HSA-532668;MetaCyc: PWY-7918;MetaCyc: PWY-7919	"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)"
XP_050577783.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling"
XP_050587686.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050594536.1	6	MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050590895.1	10	MetaCyc: PWY-7849;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394	"Urate conversion to allantoin III";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Neutrophil degranulation";"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin II"
XP_050583998.1	7	Reactome: R-HSA-1855204;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050576060.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-72662	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_050595082.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050593553.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952	"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions"
XP_050579871.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050575760.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050587912.1	17	Reactome: R-HSA-3371599;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-5744	"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Carnitine metabolism";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Glyoxylate assimilation"
XP_050599170.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-164378	"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling"
XP_050593080.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050593605.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050598494.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050577836.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050582405.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050576154.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050583613.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050593278.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050579596.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050592586.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050588042.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877	"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase"
XP_050590059.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050578140.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050573583.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_050581110.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050574447.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050589030.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050584278.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050598537.1	12	Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Rho GTPase cycle";"Relaxin signaling pathway";"mTOR signaling pathway";"G alpha (q) signalling events";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Human papillomavirus infection";"NRAGE signals death through JNK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050593964.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050594504.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050589186.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050596707.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050589418.1	9	KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.25;KEGG: 00052+3.2.1.23;Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_050581422.1	18	Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane"
XP_050590029.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_050598779.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050594113.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-176407	"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050580382.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050582255.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050586112.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050595117.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050574074.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
XP_050598433.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050599963.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050580778.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050597251.1	12	KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7238	"Galactose metabolism";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycogen synthesis";"Sucrose biosynthesis II"
XP_050589505.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050588173.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050593698.1	17	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_050597567.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555	"Adenylate cyclase inhibitory pathway";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events"
XP_050581227.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050584631.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050581406.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_050581458.1	4	MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
XP_050574329.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation"
XP_050589067.1	3	Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90	"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_050589969.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050598281.1	3	Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691	"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway";"Interleukin-20 family signaling"
XP_050581661.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159230	"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA"
XP_050594325.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050584817.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_050586025.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-72203	"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050592588.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050574217.1	14	KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-4086398;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-500657;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;Reactome: R-HSA-418217	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Ca2+ pathway";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Presynaptic function of Kainate receptors";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"G beta:gamma signalling through PLC beta"
XP_050590324.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050587940.1	14	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-977225	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation"
XP_050573642.1	5	MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210	"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_050594226.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050591025.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050589303.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050575545.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_050574215.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-399997;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-418217;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-112043;Reactome: R-HSA-434316	"Ca2+ pathway";"Acetylcholine regulates insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"G beta:gamma signalling through PLC beta";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"PLC beta mediated events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_050589355.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050589500.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050574648.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events"
XP_050593277.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050586747.1	14	Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-141444;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050590405.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050578570.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050596681.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_050581248.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050576018.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050582271.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-381676	"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_050578795.1	3	MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050589037.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050590717.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050579552.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050584824.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050581066.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-7410;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-7721	"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis"
XP_050595806.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050598185.1	10	MetaCyc: PWY-6366;Reactome: R-HSA-1855204;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.159;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6554;Reactome: R-HSA-983231;MetaCyc: PWY-6365;MetaCyc: PWY-4661;Reactome: R-HSA-1855167	"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Factors involved in megakaryocyte development and platelet production";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol"
XP_050600387.1	12	KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5278	"Purine metabolism";"Selenocompound metabolism";"Sulfur metabolism";"Selenate reduction";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Sulfur metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Assimilatory sulfate reduction III";"Sulfite oxidation III"
XP_050600308.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050587537.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050598427.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050600677.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050595558.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050590314.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_050583249.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_050575338.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins"
XP_050574263.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_050585368.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050573324.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050579395.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050594738.1	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_050584014.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_050578355.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050592590.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050577829.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050593985.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050580752.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050586580.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_050600560.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_050588077.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050582824.1	4	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions"
XP_050597569.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-164378	"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation";"PKA activation in glucagon signalling"
XP_050578337.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5610787	"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state"
XP_050589581.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050580686.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050599395.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050573589.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_050587539.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050584622.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050583430.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050576342.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050599344.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050584124.1	5	MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7536	"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_050593689.1	11	Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-3000170;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475	"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Syndecan interactions";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050579430.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_050584325.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050579528.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs"
XP_050594688.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050584955.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050595312.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050578931.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050598746.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050574930.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050595331.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050584097.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050576287.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050587293.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050574119.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-6309;MetaCyc: PWY-7717;MetaCyc: PWY-5651;Reactome: R-HSA-71240	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism"
XP_050588531.1	5	Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_050578543.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050591843.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_050594537.1	6	MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_050599275.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050596173.1	22	Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding"
XP_050598368.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_050588140.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050583749.1	8	KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7524	"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Mevalonate pathway III (archaea)"
XP_050575677.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050591842.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_050592053.1	7	KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7219;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III"
XP_050589055.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-447038	"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"NrCAM interactions"
XP_050583671.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050599069.1	26	Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-201722	"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex"
XP_050576295.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050596390.1	4	Reactome: R-HSA-8964011;Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463	"HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1"
XP_050600565.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050582832.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050593580.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050594684.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050594425.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050597926.1	15	Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-195253	"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex"
XP_050586111.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050580279.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_050595926.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050596217.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_050578158.1	7	Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism"
XP_050600108.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050588991.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_050600746.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050588662.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_050575351.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050575262.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050597594.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050586417.1	9	MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7902;MetaCyc: PWY-7385;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94	"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
XP_050595313.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050579309.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901	"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs"
XP_050575424.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050574115.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050595537.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-196299	"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade"
XP_050576970.1	4	KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation"
XP_050593555.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608	"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation"
XP_050597794.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050575291.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050579925.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050580181.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050593307.1	4	KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050593405.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5	"Synthesis of PA";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Synthesis of PG";"Glycerophospholipid metabolism"
XP_050575154.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050589714.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050580469.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050586072.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050578087.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050596345.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050592646.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050596054.1	6	Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-162594	"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle"
XP_050589721.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050581547.1	24	Reactome: R-HSA-354192;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;Reactome: R-HSA-2871837	"Integrin signaling";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"Activation of AKT2";"Downstream TCR signaling";"PIP3 activates AKT signaling";"Human papillomavirus infection";"GPVI-mediated activation cascade";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"RSK activation";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"Human cytomegalovirus infection";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"FCERI mediated NF-kB activation"
XP_050592470.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis"
XP_050578218.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050574557.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050578526.1	9	Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1362300	"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050578459.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050585133.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050582697.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050600043.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050598200.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050588298.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050596147.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050581213.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050578279.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050583767.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050582406.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050581998.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050579667.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562	"Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria"
XP_050580205.1	7	Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-180746	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein"
XP_050590027.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism"
XP_050588492.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944	"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2"
XP_050576336.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050583408.1	3	Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117	"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis"
XP_050577112.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_050592385.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050577890.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation"
XP_050579924.1	7	Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12	"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_050574621.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050580089.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050598283.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050583762.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050587285.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050574666.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050576635.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-196025	"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Formation of annular gap junctions"
XP_050573335.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_050596901.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050597612.1	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_050594342.1	10	Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761	"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_050589390.1	12	MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5857;KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-7233	"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
XP_050587188.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050574780.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Neutrophil degranulation";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050587547.1	5	Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3	"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism"
XP_050593086.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050581354.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050586377.1	5	MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism"
XP_050575389.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050594305.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050578090.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050584656.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050580405.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_050586192.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050578729.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050586302.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050582701.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050588038.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_050600265.1	10	MetaCyc: PWY-7328;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-70370	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose catabolism"
XP_050575676.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050580737.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050577283.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050587920.1	17	MetaCyc: PWY-6679;MetaCyc: PWY-5744;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2	"Jadomycin biosynthesis";"Glyoxylate assimilation";"Carnitine metabolism";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism"
XP_050586959.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050574667.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050581170.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050598104.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050597885.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I"
XP_050600107.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050591990.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050584606.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050577593.1	14	MetaCyc: PWY-3781;MetaCyc: PWY-5690;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-7279	"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)"
XP_050583892.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_050586985.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050589401.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050584234.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050600025.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050591206.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050584618.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050575904.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050600944.1	5	Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050585582.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050575766.1	9	Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168	"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)"
XP_050596688.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_050583634.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050600490.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050576023.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050589725.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050592026.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050586200.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050580829.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050587329.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050575764.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082	"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression"
XP_050590245.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050600112.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050582614.1	9	Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-7852;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-5663;MetaCyc: PWY-7442	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis"
XP_050574502.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050587642.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050589603.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050580096.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-159230	"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA"
XP_050594318.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050586108.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050584595.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050586525.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050599327.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598558.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050598442.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050600071.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050596576.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050573669.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-3371571	"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"HSF1-dependent transactivation"
XP_050573383.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050596606.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_050592060.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050584771.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050599869.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050573042.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050576629.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_050586819.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport"
XP_050596998.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050588803.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_050590612.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050573626.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050577135.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050579776.1	18	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050578361.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050578102.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050598090.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050578103.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050580688.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050596592.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_050580951.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050580754.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050576246.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050575050.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050595316.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050591835.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_050597892.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050573448.1	4	KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I";"Formation of xylulose-5-phosphate"
XP_050587472.1	6	MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391	"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_050580989.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050597546.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050580507.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050578796.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_050580560.1	6	Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;MetaCyc: PWY-6854;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685	"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species"
XP_050582509.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050594908.1	8	KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171	"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis"
XP_050587516.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050581241.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050585919.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050578039.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050596873.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050583428.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050580194.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050600784.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050590515.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050587253.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050599047.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050590516.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050594640.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane"
XP_050598324.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050595091.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050577326.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_050585049.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050582859.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050585364.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050600115.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598346.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_050588576.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050598501.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050599304.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583603.1	6	Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-8951664;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines"
XP_050580384.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050596220.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050592599.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050575582.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050591201.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69166	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate"
XP_050584530.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050589288.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_050585421.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050580887.1	1	Reactome: R-HSA-156581	"Methylation"
XP_050575776.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050588117.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050596169.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation"
XP_050600396.1	8	MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-2301;KEGG: 00521+5.5.1.4	"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Streptomycin biosynthesis"
XP_050579522.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050594361.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050583394.1	5	Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-381426	"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050592310.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050582174.1	4	Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889	"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes"
XP_050595859.1	19	Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"VLDL clearance";"Platelet sensitization by LDL";"Chylomicron remodeling";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"VLDL assembly";"Regulation of TLR by endogenous ligand";"LDL clearance";"Chylomicron clearance";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Scavenging by Class A Receptors";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis"
XP_050589599.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050590034.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050599822.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050599912.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050586121.1	6	Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_050596919.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050587947.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050589315.1	52	Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-749476;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-73980;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-203927;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529	"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"MicroRNA (miRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"FGFR2 alternative splicing"
XP_050584511.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050574435.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050599495.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050586823.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050586869.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050582298.1	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism"
XP_050576247.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050573573.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050590603.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050590024.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050574681.1	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation"
XP_050576268.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050590193.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050584892.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050578540.1	10	Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111464	"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_050575800.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_050591982.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050587281.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050587832.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050596496.1	16	Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity"
XP_050589111.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050600563.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050590574.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_050573016.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583254.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050578000.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_050583197.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050589286.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050573745.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050583883.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050596735.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription"
XP_050594734.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_050574451.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)"
XP_050576182.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050573837.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_050580676.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050597220.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050584887.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050577422.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
XP_050592760.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050581053.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-5674400;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399	"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors"
XP_050598388.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_050574938.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050580677.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050597373.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041	"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis"
XP_050577575.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_050587685.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_050585497.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050600383.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050591861.1	24	Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-202040	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G-protein activation"
XP_050583770.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050596908.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_050597368.1	16	MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;Reactome: R-HSA-2046106;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-2046105;MetaCyc: PWY-5080	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"alpha-linolenic acid (ALA) metabolism";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Linoleic acid (LA) metabolism";"Very long chain fatty acid biosynthesis I"
XP_050584890.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598559.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050575944.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_050596224.1	5	MetaCyc: PWY-7176;MetaCyc: PWY-7177;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2	"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_050593791.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-190861	"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Kinesins";"Post-chaperonin tubulin folding pathway";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Gap junction assembly"
XP_050581194.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_050575035.1	13	MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5	"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)"
XP_050589278.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050598611.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050577484.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361	"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Neurexins and neuroligins"
XP_050600605.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050598505.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050585047.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050576971.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050591387.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_050589153.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation"
XP_050589877.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050583860.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050592376.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050592381.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050590565.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050589150.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080	"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I"
XP_050593393.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050591668.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050584617.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050580131.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050593784.1	7	Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684	"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state"
XP_050592950.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050587900.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050598033.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050597180.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_050590822.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050575969.1	12	KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70263	"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis"
XP_050594859.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050578030.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050583117.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050592850.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression"
XP_050577816.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050596002.1	17	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7187	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_050599989.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050576149.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050589588.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050600966.1	8	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-4615885	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins"
XP_050576445.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050577108.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050581157.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_050578452.1	5	MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987	"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_050588912.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050580757.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050583178.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050581237.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050590659.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050591746.1	4	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism"
XP_050574151.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050585054.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5685939	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)"
XP_050576603.1	5	MetaCyc: PWY-7279;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-3781	"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)"
XP_050587477.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676	"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle"
XP_050573233.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050576919.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050590800.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050598524.1	14	MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4	"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism"
XP_050600608.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050597597.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050574453.1	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
XP_050573133.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050575205.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050587949.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050580808.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_050582343.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050582383.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050600517.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050578179.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050577175.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050596094.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_050585572.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050576925.1	12	KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5132;MetaCyc: PWY-6672;MetaCyc: PWY-5108;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5133	"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis"
XP_050581622.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_050579942.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050584826.1	4	MetaCyc: PWY-7919;KEGG: 00513+3.2.1.113;Reactome: R-HSA-901032;KEGG: 00510+3.2.1.113	"Protein N-glycosylation processing phase (plants and animals)";"Various types of N-glycan biosynthesis";"ER Quality Control Compartment (ERQC)";"N-Glycan biosynthesis"
XP_050597596.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050574111.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050592867.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050597973.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_050585866.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050597044.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050595237.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050578620.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050583386.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050597971.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050600226.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050574210.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050600903.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050597476.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050597551.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050595279.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050591391.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_050598893.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050582470.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050589728.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050597623.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1660517;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_050599804.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050583181.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-5497;Reactome: R-HSA-74259	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism"
XP_050588816.1	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_050578231.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_050594124.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_050581986.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050579873.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050580125.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050594997.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-6837;Reactome: R-HSA-9033241	"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import"
XP_050585015.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_050580651.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_050585913.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050598109.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050594453.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_050596904.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050585361.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050582553.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050574073.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
XP_050586858.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050576279.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050596562.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050600026.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050576682.1	13	Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18	"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes"
XP_050579320.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;MetaCyc: PWY-7511	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination"
XP_050573774.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050573158.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050589836.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_050575311.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050577849.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050573736.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050592230.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050599326.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050590594.1	5	Reactome: R-HSA-381038;Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-5362768	"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_050580697.1	56	Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601	"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_050600241.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050589608.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050586857.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050595426.1	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050588850.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_050595521.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050590628.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050580615.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_050594254.1	4	MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_050594435.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050573126.1	5	Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging"
XP_050588846.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050578779.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050586091.1	20	KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7288	"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_050577523.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050593362.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050583775.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs"
XP_050578367.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050585900.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_050588133.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050590209.1	11	Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-174430	"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation"
XP_050580442.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050597107.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050580115.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_050583179.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050583242.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050599904.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050578929.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050576403.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_050596558.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_050578953.1	5	Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-4655427	"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins"
XP_050589446.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050586607.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050589922.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050576999.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-420029;Reactome: R-HSA-2173791	"Asymmetric localization of PCP proteins";"Tight junction interactions";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_050600428.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050600221.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050587577.1	7	Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796	"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_050596949.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_050576765.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050582548.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050596955.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050593868.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050600340.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_050597613.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_050600497.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050583823.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-5663	"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_050584227.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050577951.1	12	Reactome: R-HSA-1839117;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Signaling by cytosolic FGFR1 fusion mutants";"Rho GTPase cycle";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling by FGFR1 in disease";"Human cytomegalovirus infection";"Human papillomavirus infection";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050600566.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_050579455.1	7	Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;MetaCyc: PWY-7836;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-5129	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_050592538.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050590420.1	14	KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_050595915.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation"
XP_050585496.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050579081.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050582202.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_050574949.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050600584.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050588811.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050573824.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050595382.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050586419.1	9	MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118	"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle"
XP_050598278.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050596529.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050581393.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050598370.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_050584647.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050588115.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050592500.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_050582486.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-167200	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050575438.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050585960.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050594071.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-7383;MetaCyc: PWY-8040	"D-Alanine metabolism";"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis"
XP_050579361.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050578321.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050585492.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_050580614.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_050598502.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050593717.1	5	Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3	"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)"
XP_050599035.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050575153.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050589673.1	10	MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842	"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II"
XP_050580275.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_050596512.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050581540.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050592518.1	7	MetaCyc: PWY-6605;MetaCyc: PWY-7807;Reactome: R-HSA-74217;MetaCyc: PWY-6610;MetaCyc: PWY-7805;KEGG: 00230+2.4.2.7;Reactome: R-HSA-6798695	"Adenine and adenosine salvage II";"Glyphosate degradation III";"Purine salvage";"Adenine salvage";"(aminomethyl)phosphonate degradation";"Purine metabolism";"Neutrophil degranulation"
XP_050596971.1	5	Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16	"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway"
XP_050582549.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050583863.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050574690.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050592451.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050598325.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050593595.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050600502.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050573565.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050574008.1	16	Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-8951664;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Neddylation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events"
XP_050586935.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050577834.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050587763.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050597250.1	12	Reactome: R-HSA-3322077;MetaCyc: PWY-7238;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9	"Glycogen synthesis";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Galactose metabolism"
XP_050589997.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050592035.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050597045.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050593744.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050579353.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050587667.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050590559.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050579402.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050596732.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050584023.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050576015.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050594159.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050573329.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050584475.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050595374.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050585799.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate"
XP_050597893.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050597562.1	11	Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568	"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050596841.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_050590987.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050594558.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050590232.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050588072.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050594464.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition"
XP_050597489.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050581735.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_050584979.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050592259.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_050594862.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050589271.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_050594193.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050584895.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050598510.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4	"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism"
XP_050573568.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050578403.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050578797.1	3	MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050591703.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050577761.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050591249.1	4	MetaCyc: PWY-7250;Reactome: R-HSA-1362409;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism"
XP_050581017.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050581626.1	8	Reactome: R-HSA-73614;Reactome: R-HSA-6798695;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193	"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_050590967.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050594356.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050574572.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_050590493.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_050595303.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050574816.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050590422.1	5	MetaCyc: PWY-5531;MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37	"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism"
XP_050586130.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050595291.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport"
XP_050580413.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050586233.1	13	MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101	"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation"
XP_050583184.1	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-7442	"Purine metabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis"
XP_050587870.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050579525.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling"
XP_050583041.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050588155.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_050593766.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050587599.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050585922.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050575304.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_050586510.1	10	KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-5022;Reactome: R-HSA-916853;MetaCyc: PWY-6537;KEGG: 00250+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6536;KEGG: 00410+2.6.1.19	"Propanoate metabolism";"4-aminobutanoate degradation I";"4-aminobutanoate degradation V";"Degradation of GABA";"4-aminobutanoate degradation II";"Alanine, aspartate and glutamate metabolism";"Butanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation III";"beta-Alanine metabolism"
XP_050580288.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050589868.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050600559.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050599484.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050577814.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050588304.1	11	Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050587924.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050575773.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050584166.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050593461.1	5	MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;MetaCyc: PWY-7790;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine biosynthesis"
XP_050591629.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050597985.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050594710.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_050583689.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050590881.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18	"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_050575647.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012	"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050578274.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050587909.1	17	MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Pyruvate metabolism"
XP_050592449.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050573772.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050582693.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_050573438.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050584716.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-7082	"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_050586018.1	4	Reactome: R-HSA-4570464;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-9610379	"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events"
XP_050578591.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050577636.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050594201.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050582715.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050578772.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050573430.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_050585942.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050599981.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050577629.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050598959.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050578303.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050583911.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050596521.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050577265.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050594776.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050578869.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050595851.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946	"Meiotic synapsis";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin"
XP_050577508.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050582826.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050584629.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050584876.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050578802.1	3	Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Platelet degranulation";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050574270.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050579519.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-5685939	"Digestion of dietary carbohydrate";"HDR through MMEJ (alt-NHEJ)"
XP_050580682.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_050587040.1	9	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Neddylation"
XP_050593559.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952	"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions"
XP_050573663.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719	"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors"
XP_050584674.1	6	KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_050581793.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050590381.1	9	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_050595281.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_050577627.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050584085.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Activation of RAC1";"Human papillomavirus infection"
XP_050573048.1	8	MetaCyc: PWY-7573;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5740;MetaCyc: PWY-5739;KEGG: 00051+4.2.1.47	"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-L-colitose biosynthesis";"GDP-D-perosamine biosynthesis";"Fructose and mannose metabolism"
XP_050580751.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050592041.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050582297.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_050578191.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050584919.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050587894.1	56	Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5689880	"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases"
XP_050573638.1	4	MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis"
XP_050595935.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050591944.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_050598538.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050581124.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050588777.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050580830.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050585924.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050574356.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050576163.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050592097.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050584375.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;MetaCyc: PWY-7511	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Protein ubiquitination"
XP_050582240.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation"
XP_050585959.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050581242.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050580090.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050587890.1	5	MetaCyc: PWY-2201;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20	"Folate transformations I";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate"
XP_050577621.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_050588136.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050584727.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050597873.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050587550.1	5	MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6122	"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_050573607.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050595801.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050573587.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_050574121.1	33	KEGG: 00830+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-6871;MetaCyc: PWY-5480;MetaCyc: PWY-5079;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-6313;MetaCyc: PWY-5082;KEGG: 00071+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-5078;MetaCyc: PWY-1801;KEGG: 00010+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00980+1.1.1.1;KEGG: 00626+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-7798;KEGG: 00625+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-7396;MetaCyc: PWY-6802;MetaCyc: PWY-5076;MetaCyc: PWY-5751;MetaCyc: PWY-5057;MetaCyc: PWY-6342;MetaCyc: PWY-3162;MetaCyc: PWY-7118;MetaCyc: PWY-6333;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5486;KEGG: 00260+1.1.1.1	"Retinol metabolism";"Pyruvate fermentation to ethanol III";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol I";"L-phenylalanine degradation III";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to isobutanol (engineered)";"Serotonin degradation";"L-methionine degradation III";"Fatty acid degradation";"Ethanol oxidation";"L-isoleucine degradation II";"Formaldehyde oxidation II (glutathione-dependent)";"Glycolysis / Gluconeogenesis";"alpha-Linolenic acid metabolism";"Metabolism of xenobiotics by cytochrome P450";"Naphthalene degradation";"Tyrosine metabolism";"Protein S-nitrosylation and denitrosylation";"Chloroalkane and chloroalkene degradation";"(S)-propane-1,2-diol degradation";"Butanol and isobutanol biosynthesis (engineered)";"Salidroside biosynthesis";"L-leucine degradation III";"Phenylethanol biosynthesis";"L-valine degradation II";"Noradrenaline and adrenaline degradation";"L-tryptophan degradation V (side chain pathway)";"Chitin degradation to ethanol";"Acetaldehyde biosynthesis I";"Methane metabolism";"Pyruvate fermentation to ethanol II";"Glycine, serine and threonine metabolism"
XP_050599074.1	26	Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression"
XP_050579393.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation"
XP_050597429.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050586667.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050574148.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050574312.1	8	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_050594161.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050588384.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050594070.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040	"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis"
XP_050598598.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050595772.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_050583396.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_050589862.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729	"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050597463.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050593270.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer"
XP_050587690.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050573087.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050588660.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050578898.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050593866.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_050581732.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_050580094.1	33	Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-168325	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis"
XP_050597073.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050599071.1	26	Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_050581951.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050576538.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050579074.1	17	Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-69183;Reactome: R-HSA-174417	"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis"
XP_050584709.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_050600255.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I"
XP_050578128.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050584382.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583906.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-176407	"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050583437.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050581102.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_050573878.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_050600498.1	14	KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-8051;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4	"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_050579790.1	18	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Translation initiation complex formation"
XP_050583221.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling"
XP_050575688.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583590.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050593265.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050588380.1	13	Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-1474244;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-2022090	"NCAM1 interactions";"Signaling by PDGF";"ECM proteoglycans";"Laminin interactions";"Extracellular matrix organization";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"Collagen degradation";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Assembly of collagen fibrils and other multimeric structures"
XP_050599072.1	26	Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050589488.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050574819.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050585931.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_050595936.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050600975.1	8	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-4615885	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins"
XP_050583796.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050573678.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9022692	"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity"
XP_050574818.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050583659.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050594667.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050579800.1	18	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Translation initiation complex formation"
XP_050576955.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050583950.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050600367.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050591889.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050590597.1	29	Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-3108214;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-912446;Reactome: R-HSA-3371511;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"SUMOylation of DNA damage response and repair proteins";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Meiotic recombination";"HSF1 activation";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER"
XP_050577662.1	7	Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-381070	"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones"
XP_050584076.1	2	Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_050598763.1	7	KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;MetaCyc: PWY-5188;Reactome: R-HSA-6782315	"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol"
XP_050573846.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_050588029.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_050594601.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050579994.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050596497.1	16	Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408	"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation"
XP_050585070.1	7	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER"
XP_050585184.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050573680.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-438066	"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ion homeostasis";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_050581214.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_050600070.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050587066.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_050585379.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050590737.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050577114.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050600391.1	12	KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4	"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Purine metabolism";"Selenocompound metabolism";"Sulfur metabolism";"Selenate reduction";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Sulfur metabolism"
XP_050581979.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050592127.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050577026.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050598972.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050582825.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050594721.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050592472.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins";"MHC class II antigen presentation"
XP_050596817.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050575778.1	5	Reactome: R-HSA-75896;Reactome: R-HSA-9033500;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241	"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Peroxisomal protein import"
XP_050596053.1	6	Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5685939	"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)"
XP_050589985.1	5	Reactome: R-HSA-8951664;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825;Reactome: R-HSA-5689603;Reactome: R-HSA-917937	"Neddylation";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases";"Iron uptake and transport"
XP_050586828.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050577293.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050598487.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050588730.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050587341.1	9	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050591331.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050585771.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-113507	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_050591812.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050598232.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050577746.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050579460.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050599330.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583992.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050592794.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_050574496.1	7	KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_050583742.1	8	KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7524	"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway III (archaea)"
XP_050583229.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050583180.1	6	MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-7442	"Guanosine nucleotides degradation II";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis"
XP_050593008.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050591630.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050576625.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050592142.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050583383.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050585180.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_050597558.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050594153.1	4	MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis"
XP_050588435.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050588324.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050586550.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050583805.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050597897.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050575907.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050596691.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050597033.1	6	MetaCyc: PWY-622;Reactome: R-HSA-3322077;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-7900	"Starch biosynthesis";"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_050578069.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050582009.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050584650.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050595892.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050589391.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-6708;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5870	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_050600106.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_050586070.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050586089.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7606	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_050578005.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050587028.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050596070.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050589028.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050584590.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050579318.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_050596900.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050589626.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_050591014.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-9615017	"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_050582822.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050581221.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050591609.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050573077.1	8	MetaCyc: PWY-5739;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-66;MetaCyc: PWY-7573;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47	"GDP-D-perosamine biosynthesis";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050576535.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050596518.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_050584634.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050588557.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_050594773.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050592464.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050577132.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050585854.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050573603.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050573734.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050580756.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050592603.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050581679.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050581490.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050579593.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050597533.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050594869.1	5	MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism"
XP_050583856.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050578407.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050584483.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050582410.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050587169.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_050585823.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_050576962.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050589109.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050589273.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_050600268.1	10	MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-3821	"Stachyose degradation";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"D-galactose detoxification"
XP_050600031.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_050593622.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050585650.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050580897.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050574687.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050576329.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050579515.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128	"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling"
XP_050581538.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050588294.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_050588392.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050589324.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050582105.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050589719.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050575384.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_050591334.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050586716.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_050594052.1	22	MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-7601;MetaCyc: PWY-8041;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7035;MetaCyc: PWY-7053;MetaCyc: PWY-7606;MetaCyc: PWY-6598;MetaCyc: PWY-6958	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)"
XP_050596874.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050598347.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_050584918.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050596715.1	10	KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04660+2.7.10.2	"Thermogenesis";"Regulation of TNFR1 signaling";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"TNFR1-induced NFkappaB signaling pathway";"T cell receptor signaling pathway"
XP_050573773.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050581507.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050580138.1	10	KEGG: 05163+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04151+2.7.1.153	"Human cytomegalovirus infection";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_050591001.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_050592025.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050598107.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050586663.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050592926.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050584003.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_050599958.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050591791.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050595769.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050596816.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050575914.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_050582008.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050597194.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050591435.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050587224.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050600243.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050600368.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050579354.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050577531.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050596348.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_050592555.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050595207.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050587828.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050595119.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_050577622.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050582148.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050596605.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_050573602.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050584806.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050582313.1	4	KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050574862.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050577903.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
XP_050581291.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050575941.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_050600441.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_050600700.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870	"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"ER-Phagosome pathway";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins"
XP_050590973.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050584997.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_050588135.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050581423.1	18	Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050573325.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050588618.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_050576244.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050581356.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050580766.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050581154.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_050596057.1	10	Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72731;Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-382556;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Recycling of eIF2:GDP";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition"
XP_050581966.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050576308.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050574530.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050583724.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050575433.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050586777.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472	"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050576273.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050600028.1	5	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex"
XP_050584655.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050580301.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050593474.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050584721.1	19	Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8950505;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-983231	"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"Myogenesis";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"Factors involved in megakaryocyte development and platelet production"
XP_050590434.1	10	MetaCyc: PWY-5890;MetaCyc: PWY-5844;MetaCyc: PWY-7996;MetaCyc: PWY-5892;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-5891;MetaCyc: PWY-5895	"Menaquinol-10 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-12 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-13 biosynthesis"
XP_050582012.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050579461.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050591404.1	8	MetaCyc: PWY-5686;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154	"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_050591844.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_050600503.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050598788.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050590376.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050590531.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050589781.1	5	Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050580916.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"PKA activation"
XP_050594203.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050594380.1	11	Reactome: R-HSA-2029485;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4	"Role of phospholipids in phagocytosis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism"
XP_050583042.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050589152.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Stearate biosynthesis I (animals)"
XP_050597977.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050576188.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050591478.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050586790.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050584131.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050585477.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050589405.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050594602.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050595380.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050577366.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050598260.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_050576178.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050592378.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050576448.1	7	MetaCyc: PWY-6351;MetaCyc: PWY-7625;Reactome: R-HSA-1483226;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system"
XP_050598714.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050586848.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050581879.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050589110.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050600184.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583669.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050594162.1	29	Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-6804760;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69541;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-349425;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568	"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Stabilization of p53";"Human papillomavirus infection";"Thermogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Human cytomegalovirus infection";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Autodegradation of the E3 ubiquitin ligase COP1";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050595747.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050589382.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050586866.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050595216.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis"
XP_050582716.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_050577565.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050594202.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050582113.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050596517.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050580915.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050595643.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050591715.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050595097.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050576932.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050583776.1	56	Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5607764	"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling"
XP_050574465.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050580820.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050589173.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050574438.1	24	Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Gap junction assembly";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"MHC class II antigen presentation"
XP_050581641.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050573331.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050578263.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_050585721.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050584630.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050573436.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050573581.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_050595775.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050592600.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050591026.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050588491.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases"
XP_050593033.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050594753.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050573971.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050598745.1	7	MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;Reactome: R-HSA-174403;MetaCyc: PWY-8043;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2	"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism"
XP_050577952.1	12	KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5655302	"Thermogenesis";"G alpha (12/13) signalling events";"Human papillomavirus infection";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants";"Human cytomegalovirus infection";"Signaling by FGFR1 in disease"
XP_050589672.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism"
XP_050577630.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050588317.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050593872.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050574240.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050593489.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050594094.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050583553.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050588118.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050589371.1	12	MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism"
XP_050580788.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050588624.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050579609.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050583465.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050592018.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050584639.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050573574.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050582266.1	13	Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-5607763	"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation"
XP_050587358.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050593564.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955	"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050580190.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050591815.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050599182.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-164378	"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"PKA activation in glucagon signalling"
XP_050579556.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050582262.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-5607763	"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation"
XP_050591793.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050598282.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050579324.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050590831.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050573328.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050584891.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050577860.1	9	Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097	"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway"
XP_050578038.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_050581121.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050582111.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050580120.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050592181.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_050580073.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050589727.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050593790.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785	"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome"
XP_050579579.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050579034.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050575017.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050581264.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_050598223.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050573390.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050584103.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_050589131.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050587098.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050600511.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050586172.1	7	KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2	"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism"
XP_050597355.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050598499.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_050574534.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050584993.1	16	Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-389357;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-1266695	"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"RET signaling";"G alpha (q) signalling events";"CD28 dependent PI3K/Akt signaling";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-7 signaling"
XP_050574333.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050578529.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_050579843.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050593673.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050573164.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-381676	"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_050590599.1	29	Reactome: R-HSA-3371511;Reactome: R-HSA-912446;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-6783310;Reactome: R-HSA-3108214;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756	"HSF1 activation";"Meiotic recombination";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Fanconi Anemia Pathway";"SUMOylation of DNA damage response and repair proteins";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation"
XP_050577861.1	9	Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097	"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway"
XP_050589666.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050578487.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_050597345.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_050590487.1	11	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_050579682.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_050577902.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence"
XP_050600417.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050574440.1	26	Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332	"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Aggrephagy";"Kinesins";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin"
XP_050584452.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050576319.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050580967.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050590741.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050576271.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050594641.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276	"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Kinesins";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"MHC class II antigen presentation";"Gap junction assembly";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_050578121.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050590870.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050598597.1	12	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Human papillomavirus infection";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"G alpha (q) signalling events";"Rho GTPase cycle";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050587829.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050574326.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050579437.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination"
XP_050580406.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_050595672.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_050580081.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050594815.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050600575.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism"
XP_050586964.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050587290.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050590215.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050583008.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050585684.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-180024	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events"
XP_050577832.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050586474.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050589335.1	13	MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate transformations II (plants)";"Folate polyglutamylation";"Metabolism of folate and pterines";"One carbon pool by folate";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes"
XP_050573434.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation"
XP_050580312.1	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781;Reactome: R-HSA-6787450	"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_050586862.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050597184.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_050574005.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050584620.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050580380.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050588876.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050583731.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050576766.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050577997.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_050579401.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050592607.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050597844.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050593557.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946	"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants"
XP_050577248.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050575276.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050579610.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_050597540.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050597272.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050581776.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050578602.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050599467.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050600366.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050592843.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_050584710.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_050598503.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_050590144.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050594501.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_050588568.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050589687.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050596947.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-416993;Reactome: R-HSA-6811434	"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050592391.1	9	Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-6901	"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation"
XP_050594120.1	5	Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-532668	"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050579896.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050589722.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050591219.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_050598203.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_050600888.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050583581.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050590363.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050577111.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs"
XP_050574354.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050574929.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050597545.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050576197.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050584473.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_050591552.1	4	MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_050593626.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050582361.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6807505;Reactome: R-HSA-983168	"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050579267.1	3	Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-4086400	"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"PCP/CE pathway"
XP_050588807.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050580811.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050577962.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050593456.1	7	KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686	"Drug metabolism - other enzymes";"UMP biosynthesis II";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050587879.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_050581352.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050589654.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_050574823.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050593233.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050579937.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050583920.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050588147.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050591551.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate"
XP_050596038.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_050578590.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050578221.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050582275.1	13	Reactome: R-HSA-5607763;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-2871809	"CLEC7A (Dectin-1) induces NFAT activation";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Ion homeostasis";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization"
XP_050592008.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050599279.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583852.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050585422.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050574774.1	11	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Thermogenesis";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050592465.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050592027.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050584593.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050577245.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050596560.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_050599274.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050599291.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583995.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050573352.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050575258.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050596865.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050573199.1	22	MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-5353;MetaCyc: PWY-7728;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-7601;MetaCyc: PWY-7592;MetaCyc: PWY-7053;MetaCyc: PWY-7035;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041;MetaCyc: PWY-6958;MetaCyc: PWY-7606;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis"
XP_050582981.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050574035.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_050574773.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050593352.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050578290.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_050582350.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050573143.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870	"Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_050591969.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050600513.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050585555.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050577998.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_050597363.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050575340.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050582786.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-5658442	"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"Regulation of RAS by GAPs"
XP_050597942.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050579405.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-2151201;Reactome: R-HSA-381340	"RORA activates gene expression";"Estrogen-dependent gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation"
XP_050596868.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050580936.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050587955.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050594858.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050586384.1	10	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome"
XP_050591571.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1474151;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-6614	"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"One carbon pool by folate";"Folate biosynthesis";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis"
XP_050581577.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050576657.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_050576963.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050574068.1	3	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050582805.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050575500.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050574589.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050575682.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050589924.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050596926.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050600004.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583435.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050598557.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_050597186.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_050587464.1	7	MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_050586948.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050588241.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050577363.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050582833.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_050598326.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050598552.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050591798.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050579072.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050578046.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050599313.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050590926.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050592809.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296	"CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome"
XP_050596682.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050582276.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-5607763	"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation"
XP_050596709.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050593236.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050582071.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050588761.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050574538.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050590439.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050597830.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050573494.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050597655.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_050590938.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978	"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_050594381.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050575772.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050583231.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_050591613.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050593525.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050590775.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050586329.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228	"Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix"
XP_050597609.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050578089.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050590338.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050580056.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050582463.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050597265.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050589663.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050589852.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050590398.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-174113	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1"
XP_050583555.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050592769.1	5	Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
XP_050596457.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_050574640.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_050575208.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_050590869.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050590566.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_050593674.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050576746.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050580791.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050584619.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050593591.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530	"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_050593691.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050573840.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_050583774.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_050581204.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050580578.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050588776.1	9	Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288	"mTOR signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1"
XP_050593495.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050573026.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_050594447.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050578364.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050592643.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050600299.1	5	Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;Reactome: R-HSA-71336;MetaCyc: PWY-8060	"Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I"
XP_050596896.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050577675.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_050600606.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050600494.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050592854.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050599763.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050590897.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050598431.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050587548.1	5	KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_050594328.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Synthesis of PA"
XP_050599445.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-5617472	"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050577365.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050578489.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050585238.1	10	Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11	"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism"
XP_050583882.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050598093.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050587454.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_050596544.1	5	KEGG: 00270+1.1.1.95;MetaCyc: PWY-8010;KEGG: 00680+1.1.1.95;Reactome: R-HSA-977347;KEGG: 00260+1.1.1.95	"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_050587925.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050574083.1	12	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-982772;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-75893;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Growth hormone receptor signaling";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"TNF signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4"
XP_050597185.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_050582901.1	11	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation"
XP_050586618.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050586662.1	8	KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27	"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism"
XP_050586714.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050580701.1	28	Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-3371511;Reactome: R-HSA-912446;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453	"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"HSF1 activation";"Meiotic recombination";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response"
XP_050592461.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_050597293.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050577421.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050597847.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050594216.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050581255.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_050595684.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_050574029.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-168928;Reactome: R-HSA-9639288	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Amino acids regulate mTORC1"
XP_050584380.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050578232.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_050579631.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050598369.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_050582663.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050594605.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050600484.1	8	Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111463	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs"
XP_050600601.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050587344.1	9	KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050577529.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050599328.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050597795.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050585205.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050588055.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_050576423.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050577088.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050582360.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050598715.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050598960.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050576891.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_050584449.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050596004.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050577668.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050573399.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_050594355.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050579603.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167152	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_050600432.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484	"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_050600351.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_050588771.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050586917.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050599986.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050594006.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050575349.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050592283.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050578758.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050597513.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050598592.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050587551.1	5	Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3	"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism"
XP_050587060.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050597000.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050574913.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_050580827.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050588631.1	11	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050580748.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453	"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response"
XP_050586933.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050591149.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050596389.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050585554.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050592649.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050588561.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050590794.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050595749.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050584604.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050592667.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050584057.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050598226.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050599752.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050588783.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050599508.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050596060.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination"
XP_050591894.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050598516.1	14	KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_050600437.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484	"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_050589422.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050573435.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050598394.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_050578238.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050594170.1	29	Reactome: R-HSA-349425;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693548;KEGG: 05163+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-69541;Reactome: R-HSA-5693607;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-6804760;Reactome: R-HSA-5693554	"Autodegradation of the E3 ubiquitin ligase COP1";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Sensing of DNA Double Strand Breaks";"Human cytomegalovirus infection";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Thermogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Stabilization of p53";"Processing of DNA double-strand break ends";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"Homologous DNA Pairing and Strand Exchange";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050574118.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050585855.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050590410.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050580431.1	9	Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"MAP2K and MAPK activation";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_050582425.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_050583209.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050577809.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050587895.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257	"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"UCH proteinases";"Degradation of AXIN"
XP_050596897.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050598498.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050596972.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409	"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation"
XP_050592774.1	5	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_050591029.1	5	Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20	"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism"
XP_050596061.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050584350.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050573017.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050584637.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050584523.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_050577880.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050593210.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050600442.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_050581168.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050591015.1	10	Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538	"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA"
XP_050593524.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050591611.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050582077.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050594135.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050573599.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050575791.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050598509.1	14	KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409	"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_050600953.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs"
XP_050587200.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050575822.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_050578157.1	7	MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6121	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_050597549.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050584720.1	19	Reactome: R-HSA-2029482;Reactome: R-HSA-8950505;Reactome: R-HSA-5663213;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-983231;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-418885;Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-5663220;Reactome: R-HSA-525793	"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"EGFR downregulation";"Factors involved in megakaryocyte development and platelet production";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"DCC mediated attractive signaling";"Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"RHO GTPases Activate Formins";"Myogenesis"
XP_050587592.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050591765.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050600946.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050599992.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050594755.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050597372.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I"
XP_050587430.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050585201.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050581134.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-113418	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex"
XP_050583826.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_050590832.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050596903.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_050596876.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050583773.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050577812.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050573474.1	8	Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1	"Glycolysis";"Streptomycin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism"
XP_050596990.1	33	Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_050587403.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050594136.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050587131.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_050593153.1	6	Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_050577734.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050574470.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050592476.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050593102.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411	"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere"
XP_050591853.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_050586974.1	18	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-5693565;Reactome: R-HSA-1221632;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Protein ubiquitination";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic synapsis";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins"
XP_050579912.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_050598484.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_050581187.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050591560.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050600301.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_050589040.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050586090.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-735	"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis"
XP_050583018.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050589724.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050591854.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_050594051.1	22	MetaCyc: PWY-5353;MetaCyc: PWY-7728;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7049;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041;MetaCyc: PWY-6958;MetaCyc: PWY-7606;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7592	"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)"
XP_050574574.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050597037.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050580379.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050580377.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050593484.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050588120.1	40	Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-75955;Reactome: R-HSA-203927;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-5617472	"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Elongation";"MicroRNA (miRNA) biogenesis";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050587455.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050589662.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050595347.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_050579801.1	18	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_050599962.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050595245.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050593619.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050597425.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050579772.1	18	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol"
XP_050578045.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050579939.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050596952.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Macroautophagy"
XP_050579212.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050594840.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050591396.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050596683.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050591114.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050588071.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050582082.1	19	Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-381426	"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Platelet sensitization by LDL";"VLDL clearance";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Chylomicron remodeling";"LDL remodeling";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Scavenging by Class H Receptors";"Chylomicron clearance";"Post-translational protein phosphorylation";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050595914.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050586679.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050577822.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050584772.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050596346.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_050576838.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation"
XP_050583169.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050590037.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_050582311.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-983231	"Growth hormone receptor signaling";"Signaling by Leptin";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_050586764.1	11	MetaCyc: PWY-6606;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6596;MetaCyc: PWY-5497;MetaCyc: PWY-6999;MetaCyc: PWY-6607;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6538;MetaCyc: PWY-5695	"Guanosine nucleotides degradation II";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Guanosine nucleotides degradation I";"Caffeine metabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation"
XP_050591953.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050593556.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_050589475.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050573230.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050584633.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050589172.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050589717.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050579218.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050591140.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050588067.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050576744.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050592096.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050577808.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050583115.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050576375.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8051	"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I"
XP_050579779.1	18	Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050579975.1	5	KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_050593832.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050589598.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050592576.1	4	KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050599762.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050595727.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050576900.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050573639.1	5	Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I"
XP_050577745.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050591207.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050578119.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050593237.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050580957.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050575492.1	14	KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5078;MetaCyc: PWY-5104;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5057;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-7767	"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"L-isoleucine degradation II";"L-isoleucine biosynthesis IV";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"L-valine degradation II";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-leucine degradation IV (Stickland reaction)"
XP_050574770.1	11	Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Human papillomavirus infection";"Thermogenesis"
XP_050598227.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050576914.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050583872.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050599535.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050589762.1	10	Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Recycling pathway of L1";"Human cytomegalovirus infection";"RSK activation";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human papillomavirus infection";"Thermogenesis"
XP_050600394.1	10	MetaCyc: PWY-6683;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6932	"Assimilatory sulfate reduction III";"Sulfite oxidation III";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Sulfur metabolism";"Sulfate activation for sulfonation";"Selenate reduction"
XP_050596695.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050595348.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_050587582.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050590145.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050577229.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050578016.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050574916.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050596055.1	10	Reactome: R-HSA-72702;Reactome: R-HSA-382556;Reactome: R-HSA-9648895;Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72731	"Ribosomal scanning and start codon recognition";"ABC-family proteins mediated transport";"Response of EIF2AK1 (HRI) to heme deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Recycling of eIF2:GDP"
XP_050580116.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050591867.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_050583952.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050598853.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_050583592.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050597602.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050582853.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050582970.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050575002.1	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
XP_050597599.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050598220.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation"
XP_050595437.1	4	MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism"
XP_050590202.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050575287.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050597025.1	6	KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165	"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_050589504.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050600518.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050576537.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050592930.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050579867.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050593180.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-180910	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Vpr-mediated nuclear import of PICs"
XP_050580480.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050576193.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050578336.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838	"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO"
XP_050582407.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050585074.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050578955.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_050591032.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Termination of translesion DNA synthesis";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_050575646.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050591372.1	13	MetaCyc: PWY-7184;KEGG: 00230+3.6.1.66;KEGG: 00740+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Riboflavin metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_050588379.1	13	Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-2243919	"NCAM1 interactions";"Signaling by PDGF";"ECM proteoglycans";"Extracellular matrix organization";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Crosslinking of collagen fibrils"
XP_050574446.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050577758.1	18	MetaCyc: PWY-7226;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7222	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_050590377.1	12	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-6804756	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation"
XP_050597746.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050589681.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729	"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050585103.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050581116.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050598103.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050579785.1	18	Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination"
XP_050592746.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_050575458.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050587339.1	9	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol"
XP_050595549.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050587816.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_050586305.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050581071.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050593121.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050598099.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050574109.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050598234.1	7	MetaCyc: PWY-7185;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7198	"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_050600867.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050581159.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_050583877.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions"
XP_050578285.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050592122.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050593547.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608	"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation"
XP_050588026.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy"
XP_050597487.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050579476.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050580030.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex"
XP_050582209.1	2	MetaCyc: PWY-8061;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification II";"Phosphate bond hydrolysis by NUDT proteins"
XP_050573327.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050579325.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877	"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase"
XP_050588849.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_050594084.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050589178.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050576493.1	12	MetaCyc: PWY-5855;MetaCyc: PWY-5870;KEGG: 00130+2.5.1.39;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-6978;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-6708;Reactome: R-HSA-1268020	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import"
XP_050598401.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_050587390.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5658442	"Separation of Sister Chromatids";"ER-Phagosome pathway";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of RAS by GAPs"
XP_050584603.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050595937.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050583988.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050591610.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050598607.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050595745.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050594208.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050591879.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-68949	"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin"
XP_050590139.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_050589776.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729	"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050596041.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_050590982.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_050582422.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050592133.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050587084.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050581384.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050594954.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050575890.1	6	Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation"
XP_050576585.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_050598118.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050581778.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050584521.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050586966.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050581155.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_050576333.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050599273.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050595106.1	7	KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism"
XP_050596324.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_050576181.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050589699.1	56	Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870	"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins"
XP_050579938.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050576681.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane"
XP_050590598.1	29	Reactome: R-HSA-3108214;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-912446;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Meiotic recombination";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER"
XP_050585405.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050584047.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050591004.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_050586958.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050577999.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_050596855.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050580099.1	33	Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168325	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis"
XP_050579028.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050581434.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_050598105.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050583189.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050583116.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050582501.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050590485.1	11	Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802	"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3"
XP_050593948.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050592042.1	6	KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_050581408.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050588378.1	13	Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-3000178	"Anchoring fibril formation";"Collagen degradation";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Laminin interactions";"Signaling by PDGF";"NCAM1 interactions";"ECM proteoglycans"
XP_050575257.1	52	Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-73780;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-167290;Reactome: R-HSA-73980;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-76071;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-5617472	"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Chain Elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050598702.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050579211.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050587482.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050585018.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050585499.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050585371.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050580476.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050589356.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050594259.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_050590267.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050586469.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050578105.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050584641.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050581462.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050590355.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_050599488.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_050581302.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050593861.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050581219.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050598153.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050576170.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174178	"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_050589710.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050583433.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050589034.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050591002.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_050578173.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050579408.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050581787.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-9627069	"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity"
XP_050584642.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050590137.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050577961.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050576935.1	8	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Caspase activation via Dependence Receptors in the absence of ligand";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_050574418.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-201722;Reactome: R-HSA-2173796	"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Formation of the beta-catenin:TCF transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_050588394.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050588391.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050591332.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050579868.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050576767.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050576062.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050578359.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050598967.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050580819.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050600016.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050596533.1	12	KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-6683;MetaCyc: PWY-5278	"Purine metabolism";"Selenocompound metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Selenate reduction";"Sulfur metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Assimilatory sulfate reduction III";"Sulfite oxidation III"
XP_050595633.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050596192.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_050582320.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050585071.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050589971.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050583044.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050580673.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050574313.1	8	Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050590157.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport"
XP_050600514.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050580439.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050584671.1	6	MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_050583051.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050584549.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050577246.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050577218.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050582834.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050577887.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050594431.1	17	Reactome: R-HSA-1433557;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-176187	"Signaling by SCF-KIT";"Relaxin signaling pathway";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"Human cytomegalovirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of ATR in response to replication stress"
XP_050589595.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050577813.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050587340.1	9	KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_050583824.1	6	MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-7442	"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis"
XP_050573601.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050578409.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050579082.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050584001.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_050595033.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050589584.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050575255.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050587404.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
XP_050573771.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050592276.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050598475.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050582264.1	13	Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-983695	"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Ion homeostasis";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_050592359.1	13	Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-975163	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
XP_050574937.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050595195.1	4	KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050580769.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050574917.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_050598548.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050580685.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050588578.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050592136.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050579327.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050577760.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050584176.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050588068.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050586824.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050597531.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050578615.1	15	Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-141430	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_050596931.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050579436.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_050573623.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050588025.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050579612.1	15	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-9603505	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NTRK3 as a dependence receptor"
XP_050595860.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Chylomicron clearance";"LDL clearance";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Scavenging by Class A Receptors";"LDL remodeling";"Scavenging by Class F Receptors";"Chylomicron remodeling";"VLDL clearance";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Scavenging by Class B Receptors"
XP_050590629.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_050590486.1	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_050597715.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142	"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins"
XP_050579791.1	18	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
XP_050589660.1	2	Reactome: R-HSA-1433559;Reactome: R-HSA-8951664	"Regulation of KIT signaling";"Neddylation"
XP_050588993.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_050591837.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_050590818.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050589966.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050600103.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_050590606.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050592561.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050590077.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050583305.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050583013.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050593492.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_050597826.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050574272.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_050583121.1	4	Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841	"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_050577616.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050596958.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_050580490.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050584968.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050590859.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050591384.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050573566.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050592422.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050587198.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52	"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation"
XP_050582794.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050590795.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050584983.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050597126.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050580645.1	5	Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88	"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism"
XP_050582478.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050576260.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050588043.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation"
XP_050594686.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050578517.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_050589002.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_050584984.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050585912.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050600611.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050579293.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050590744.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050586235.1	13	Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822	"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)"
XP_050589045.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050586945.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050587937.1	14	Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1474228;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695	"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of the extracellular matrix";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation"
XP_050579521.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050599966.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050592917.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050588878.1	42	MetaCyc: PWY-7094;MetaCyc: PWY-7606;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7007;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7778;MetaCyc: PWY-5177;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00640+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-6863;MetaCyc: PWY-7779;KEGG: 00903+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-6883;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7656;MetaCyc: PWY-6435;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-6583;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35	"Fatty acid salvage";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Tryptophan metabolism";"Benzoyl-coa degradation I (aerobic)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"2-methylpropene degradation";"Glutaryl-coa degradation";"Phenylalanine metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Benzoate degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Fatty acid elongation";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Pyruvate fermentation to hexanol (engineered)";"Methyl tert-butyl ether degradation";"Limonene and pinene degradation";"Butanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Spodoptera littoralis pheromone biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"Caprolactam degradation";"beta-Alanine metabolism";"Androstenedione degradation";"Pyruvate fermentation to butanol I";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation"
XP_050577674.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_050598344.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_050580436.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_050583953.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050599777.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050574398.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_050589619.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050578190.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050584508.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050595751.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_050578738.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress"
XP_050577267.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050575220.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050594427.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050600443.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_050579796.1	18	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050584463.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050580715.1	5	MetaCyc: PWY-7210;Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Purine metabolism"
XP_050592815.1	12	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Human papillomavirus infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_050598114.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050574116.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050596078.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_050588994.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050597258.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619	"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN"
XP_050592380.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050593041.1	17	KEGG: 04714+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 05163+2.7.11.1	"Thermogenesis";"Meiotic synapsis";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"mTOR signaling pathway";"Fanconi Anemia Pathway";"Human cytomegalovirus infection"
XP_050581225.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050579996.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050596930.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050575855.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519	"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression"
XP_050597349.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050595810.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050585210.1	14	Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5687128	"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling"
XP_050579509.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050588597.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050576772.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050587621.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050582083.1	19	Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480	"Scavenging by Class F Receptors";"Chylomicron remodeling";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"VLDL clearance";"Platelet sensitization by LDL";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Post-translational protein phosphorylation";"LDL clearance";"Scavenging by Class H Receptors";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"LDL remodeling";"Scavenging by Class A Receptors"
XP_050591947.1	18	Reactome: R-HSA-1482922;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4	"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism"
XP_050591926.1	57	Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Separation of Sister Chromatids";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Degradation of AXIN";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs"
XP_050600496.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050581812.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050584995.1	16	Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-1266695;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604	"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"Interleukin-7 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"RET signaling";"G alpha (q) signalling events";"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling"
XP_050581282.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050585878.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050581253.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_050575059.1	5	Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_050594166.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050573972.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050594295.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050577633.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050584610.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050595120.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_050577281.1	16	Reactome: R-HSA-975138;Reactome: R-HSA-5602498;Reactome: R-HSA-975110;Reactome: R-HSA-1257604;Reactome: R-HSA-5603037;Reactome: R-HSA-209543;Reactome: R-HSA-166058;Reactome: R-HSA-3134963;Reactome: R-HSA-6811558;Reactome: R-HSA-5603041;Reactome: R-HSA-975871;Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-9020702;Reactome: R-HSA-5602680;Reactome: R-HSA-1810476	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR5)";"p75NTR recruits signalling complexes";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"Interleukin-1 signaling";"MyD88 deficiency (TLR5)";"RIP-mediated NFkB activation via ZBP1"
XP_050598362.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_050596914.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050594214.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050597484.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050595310.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050599335.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050596878.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050573226.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050575129.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050596722.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050595084.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050584525.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050586385.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228	"Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix"
XP_050586237.1	13	KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7883	"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II"
XP_050590392.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050591999.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050582717.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050583163.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_050582632.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050595118.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050587575.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050582551.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050585976.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050577810.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050574653.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_050573753.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050587926.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050588571.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050599269.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050576964.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050594597.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050579577.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050594682.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050575491.1	14	KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5076;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-7767;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5108;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101	"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"L-leucine degradation III";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"L-isoleucine degradation II";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"L-leucine degradation IV (Stickland reaction)";"Pantothenate and CoA biosynthesis";"L-valine degradation II";"L-isoleucine biosynthesis V";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II"
XP_050599181.1	11	Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-164378	"G alpha (s) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"PKA activation in glucagon signalling"
XP_050593620.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050580416.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_050598511.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053	"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II"
XP_050590825.1	9	MetaCyc: PWY-6146;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-6142	"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050576498.1	7	KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176	"Drug metabolism - other enzymes";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"UTP and CTP de novo biosynthesis"
XP_050588255.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050594273.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050573185.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Neutrophil degranulation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_050582609.1	4	MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_050600065.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050575245.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_050578084.1	7	Reactome: R-HSA-5693565;Reactome: R-HSA-69473;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-983168;Reactome: R-HSA-3108214	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Protein ubiquitination";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins"
XP_050579409.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050583771.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs"
XP_050593084.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050582003.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050583658.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050594853.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050593081.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050575159.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050577789.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050577159.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050587866.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050597369.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050594194.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050588098.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_050574645.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_050586400.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_050579208.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050593374.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050588395.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050585170.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050576983.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305	"Neutrophil degranulation";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D"
XP_050599307.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050576280.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050587535.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050588424.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050579714.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050585222.1	33	Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA"
XP_050587336.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_050592187.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050586342.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050575659.1	6	KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346	"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)"
XP_050591199.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050580117.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050589949.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050579893.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050597267.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050584476.1	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_050579016.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050596915.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050597264.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050574531.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050596422.1	2	Reactome: R-HSA-69231;Reactome: R-HSA-8934593	"Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity"
XP_050583451.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050591479.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050594864.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050598067.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050574632.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050574394.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_050597257.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050598591.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050597884.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050596711.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050583832.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050579762.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_050590374.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167287	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery"
XP_050582477.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050579170.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050590147.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_050596498.1	16	Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes"
XP_050584678.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_050581224.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050600227.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_050589718.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050592261.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050584226.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050600615.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050576773.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050592277.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050573665.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_050597003.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050585130.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050586317.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_050590590.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_050584158.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050580091.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050593212.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050586220.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050574563.1	3	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism"
XP_050586020.1	4	Reactome: R-HSA-4570464;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-9610379	"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events"
XP_050585374.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050599727.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050582616.1	9	MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6703;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-7852	"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)"
XP_050574482.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050594365.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050597978.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050596494.1	16	Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408	"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation"
XP_050594580.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050576933.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050599844.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050600755.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_050574208.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050590965.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050581669.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050578354.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050573882.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050596008.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050586238.1	13	KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II"
XP_050584558.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050600567.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_050583628.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-176187	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress"
XP_050582081.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050592440.1	4	KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603	"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine"
XP_050574488.1	4	Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761	"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_050600307.1	6	KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;MetaCyc: PWY-6908;MetaCyc: PWY-7356;MetaCyc: PWY-6907;Reactome: R-HSA-196819	"Thiamine metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism"
XP_050573821.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050597736.1	19	Reactome: R-HSA-1799339;Reactome: R-HSA-3214858;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-8876725;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Protein methylation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination"
XP_050584676.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050598527.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050581289.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050583984.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050595662.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050588483.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050580475.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050580764.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050586797.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9609690	"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"HCMV Early Events"
XP_050580906.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050593438.1	7	MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790	"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis II"
XP_050573808.1	15	KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-6901	"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation"
XP_050573950.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050591786.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050578912.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-1632852	"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy"
XP_050589601.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050583283.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling"
XP_050584653.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050592426.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050600208.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050578002.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050589038.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050598762.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_050588574.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050578376.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050573677.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_050574811.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050573514.1	10	Reactome: R-HSA-913709;MetaCyc: PWY-7661;MetaCyc: PWY-7979;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4717374;MetaCyc: PWY-7921;Reactome: R-HSA-162699;MetaCyc: PWY-7922;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377	"O-linked glycosylation of mucins";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation III (mammals, core M3)";"N-Glycan biosynthesis";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)"
XP_050587280.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050582445.1	3	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway"
XP_050584095.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050581539.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050582394.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050579576.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050574656.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050599723.1	5	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_050595980.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_050597848.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050594225.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050578322.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050575680.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050593087.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050576956.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050579804.1	18	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Translation initiation complex formation"
XP_050584064.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050584193.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050581286.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050579229.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050584794.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050587295.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050575253.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050592832.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555	"Downstream signal transduction";"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1"
XP_050584594.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050599277.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050581109.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050581580.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050581277.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050580228.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_050588532.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050598966.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050575882.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_050588533.1	5	KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_050590842.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050582785.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921	"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation"
XP_050590841.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050594956.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050582261.1	13	Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775	"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Ion homeostasis"
XP_050590373.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050584053.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050591873.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050577635.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050580013.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050595210.1	6	Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_050585560.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050594500.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050574223.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_050583849.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050596736.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050597833.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050579306.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050595202.1	6	MetaCyc: PWY-7920;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952	"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_050578814.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_050582784.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050594155.1	4	KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis"
XP_050581068.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050585098.1	17	Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-112382;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167158;KEGG: 04660+3.1.3.16;Reactome: R-HSA-75955	"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Th1 and Th2 cell differentiation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"T cell receptor signaling pathway";"RNA Polymerase II Transcription Elongation"
XP_050600905.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050592961.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050593765.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050598670.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050580656.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050576298.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050595075.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050577271.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050590313.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050577527.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050592537.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050584746.1	13	Reactome: R-HSA-416572;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 04714+2.7.11.1	"Sema4D induced cell migration and growth-cone collapse";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Human papillomavirus infection";"EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"Thermogenesis"
XP_050577993.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050590421.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-5531	"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_050575019.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050580683.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050579747.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050581438.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_050595866.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_050574954.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050593655.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5913	"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)"
XP_050575657.1	6	MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22	"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism"
XP_050595150.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050573351.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050575001.1	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
XP_050585697.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050597544.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050596331.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050591903.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050597433.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050577815.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050597568.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050596465.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050598100.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050577599.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050596731.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050585847.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_050577494.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_050590604.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050599214.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050584346.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050589369.1	12	MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4	"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism"
XP_050589904.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_050598508.1	14	MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4	"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism"
XP_050598023.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050574298.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050576582.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050586761.1	14	MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6538;KEGG: 00230+1.17.1.4+1.17.3.2;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6608;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6607;MetaCyc: PWY-5497;MetaCyc: PWY-6999;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6596;MetaCyc: PWY-6606	"Inosine 5'-phosphate degradation";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine metabolism";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation III";"Caffeine metabolism";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II"
XP_050594349.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050597818.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050576621.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050579718.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050589637.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_050592559.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_050597585.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050574350.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050588161.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050592872.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_050582631.1	10	MetaCyc: PWY-6362;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;MetaCyc: PWY-6554	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_050588296.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_050589454.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_050582363.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050588297.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050573101.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050576185.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050578264.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050580357.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050597938.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050580762.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050592984.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
XP_050598386.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_050578629.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050582124.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050592290.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050598735.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050581499.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050600671.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050578283.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050597807.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8953750	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6"
XP_050579322.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096	"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050589168.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)"
XP_050578118.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050579061.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050575434.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050594360.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050591340.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050577406.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050590005.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050581726.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050597236.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050576337.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050586937.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050594367.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050573823.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050597586.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050594506.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050599297.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050577243.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050582577.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050582339.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-77075	"Formation of Incision Complex in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050576275.1	5	Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936964	"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_050577203.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050578829.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050588462.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_050583232.1	9	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation"
XP_050589290.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050580286.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050585501.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050586097.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050580846.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_050573020.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050592314.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050599562.1	8	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5744	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation"
XP_050587953.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050588538.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_050585579.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050590610.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050574854.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050582959.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050586986.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050588823.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050598279.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050589396.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_050596024.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050599945.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050575522.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_050578897.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_050589602.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_050585773.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050598602.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050595440.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-171007	"mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"p38MAPK events"
XP_050584209.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_050583578.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214	"snRNP Assembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins"
XP_050584972.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation"
XP_050594335.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050580689.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050580180.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050597229.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_050595841.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946	"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin"
XP_050586092.1	20	MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6	"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism"
XP_050585370.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050584722.1	19	Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-194840;Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-114604;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8950505;Reactome: R-HSA-182971;Reactome: R-HSA-8964616;Reactome: R-HSA-5625970	"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"Myogenesis";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"Rho GTPase cycle";"Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"GPVI-mediated activation cascade";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"EGFR downregulation";"G beta:gamma signalling through CDC42";"RHO GTPases activate KTN1"
XP_050590903.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-5358346	"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis"
XP_050578015.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050579029.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050591911.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050589607.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050585945.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050579299.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050598432.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050575595.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050578743.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation"
XP_050600445.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_050589054.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-447038	"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"NrCAM interactions"
XP_050576519.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050573503.1	18	KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5913	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)"
XP_050583404.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050578890.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142	"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins"
XP_050586126.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050592423.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050580346.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-383280;Reactome: R-HSA-9018519;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-212436	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Nuclear Receptor transcription pathway";"Estrogen-dependent gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Generic Transcription Pathway"
XP_050598673.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050588434.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050587836.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050579358.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050596886.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050582248.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050584229.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050589788.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-5695;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Purine metabolism";"Drug metabolism - other enzymes"
XP_050573833.1	3	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes"
XP_050582858.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050590616.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050574456.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_050577346.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050595544.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050590613.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050596708.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050597652.1	6	Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-75955	"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation"
XP_050587536.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050573610.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050585207.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050574750.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050582011.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050591698.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050590351.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050579587.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_050598027.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050580129.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050591625.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050584996.1	16	Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6811558;Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-194840;Reactome: R-HSA-416476;Reactome: R-HSA-8853659	"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-7 signaling";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Rho GTPase cycle";"G alpha (q) signalling events";"RET signaling"
XP_050587389.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050586176.1	9	Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332	"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_050579908.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050577673.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_050577728.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050573608.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050583401.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050586381.1	10	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807	"HS-GAG degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Galactose metabolism";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_050589902.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69166	"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate"
XP_050595895.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050596954.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050582382.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050582813.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050573029.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050594319.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050582393.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-606279	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050576615.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050579317.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096	"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050594632.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors"
XP_050584071.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050593602.1	20	MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_050581492.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050583440.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050587242.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712	"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Photosynthesis";"ATP biosynthesis";"Ion channel transport"
XP_050594594.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050585367.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050580579.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050573575.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_050595222.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_050594415.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-381038	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes"
XP_050575353.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050589946.1	8	Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750	"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6"
XP_050587922.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050576659.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050581288.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050577174.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050575683.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050577362.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050600588.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050597749.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050575308.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050575763.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050595349.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_050589463.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_050590600.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050586194.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050583143.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050583584.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050590937.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050589033.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050591792.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050593354.1	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050593588.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-109704	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade"
XP_050575024.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050584448.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050595177.1	4	KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050598391.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_050585658.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050593589.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704	"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade"
XP_050579795.1	18	Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination"
XP_050599898.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050581655.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint"
XP_050574573.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_050582380.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050586074.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050593154.1	6	MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987	"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_050577741.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_050589813.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050588810.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050581494.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050581712.1	24	Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-5625740	"Activation of AKT2";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Integrin signaling";"PIP3 activates AKT signaling";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Thermogenesis";"Human papillomavirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"RSK activation";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs"
XP_050576194.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050589289.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_050577001.1	3	Reactome: R-HSA-2173791;Reactome: R-HSA-420029;Reactome: R-HSA-4608870	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Tight junction interactions";"Asymmetric localization of PCP proteins"
XP_050594341.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_050587835.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050576690.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_050589474.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050598736.1	12	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"G alpha (q) signalling events";"mTOR signaling pathway";"Relaxin signaling pathway";"Rho GTPase cycle"
XP_050587199.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050600493.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050574449.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050593441.1	7	MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes"
XP_050600005.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050573391.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050576693.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050599180.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170670	"Hedgehog 'off' state";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase inhibitory pathway"
XP_050595217.1	4	MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_050574562.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050598514.1	14	KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788	"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC"
XP_050585857.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050596686.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_050579399.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050592587.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050580650.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
XP_050580724.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050574349.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050596588.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050573346.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050585902.1	5	Reactome: R-HSA-6804756;Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-6811555	"Regulation of TP53 Activity through Phosphorylation";"ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation"
XP_050581725.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050599325.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050579802.1	18	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol"
XP_050574726.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2979096	"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050574485.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"MHC class II antigen presentation";"Gap junction assembly";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Kinesins";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_050583010.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050580241.1	30	Reactome: R-HSA-5628897;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-198693;Reactome: R-HSA-69202;Reactome: R-HSA-211163;Reactome: R-HSA-389513;Reactome: R-HSA-8941332;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1358803;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804758;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634638;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-69656;Reactome: R-HSA-8948751;Reactome: R-HSA-8876198;Reactome: R-HSA-199418;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-6804759;Reactome: R-HSA-111447;Reactome: R-HSA-1257604	"TP53 Regulates Metabolic Genes";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"AKT phosphorylates targets in the nucleus";"Cyclin E associated events during G1/S transition";"AKT-mediated inactivation of FOXO1A";"CTLA4 inhibitory signaling";"RUNX2 regulates genes involved in cell migration";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Downregulation of ERBB2:ERBB3 signaling";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Acetylation";"Human papillomavirus infection";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Regulation of localization of FOXO transcription factors";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of PTEN stability and activity";"RAB GEFs exchange GTP for GDP on RABs";"Negative regulation of the PI3K/AKT network";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Activity through Association with Co-factors";"Activation of BAD and translocation to mitochondria";"PIP3 activates AKT signaling"
XP_050582303.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050582378.1	7	Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841	"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"HCMV Early Events";"PKMTs methylate histone lysines"
XP_050597589.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050592517.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050573395.1	17	Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-5651801	"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair"
XP_050590061.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050582682.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050595409.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_050590591.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_050575482.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050575221.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050584061.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050595320.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050598757.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050597370.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I"
XP_050576402.1	22	MetaCyc: PWY-5054;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9;Reactome: R-HSA-70263;MetaCyc: PWY-622;MetaCyc: PWY-6981;MetaCyc: PWY-6142;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5384;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-8013;MetaCyc: PWY-5659;Reactome: R-HSA-6798695;MetaCyc: PWY-3801;Reactome: R-HSA-5628897;MetaCyc: PWY-6992;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9;MetaCyc: PWY-7347	"D-sorbitol biosynthesis I";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Starch biosynthesis";"Chitin biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Starch and sucrose metabolism";"Sucrose degradation IV (sucrose phosphorylase)";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"GDP-mannose biosynthesis";"Neutrophil degranulation";"Sucrose degradation II (sucrose synthase)";"TP53 Regulates Metabolic Genes";"1,5-anhydrofructose degradation";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis III"
XP_050599891.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050574926.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050586425.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_050575799.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_050599285.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050600398.1	8	KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6372	"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_050597295.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050587319.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_050584608.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050582139.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050578113.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_050573578.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_050574927.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050594600.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050583016.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050578282.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050590375.1	12	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050591003.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892	"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_050597781.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_050587159.1	4	Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261	"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_050586124.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050592124.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050588772.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_050573094.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Intraflagellar transport";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050592085.1	8	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050586017.1	4	Reactome: R-HSA-9610379;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-4570464	"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins"
XP_050588063.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050587476.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_050577605.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050583786.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050598263.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050586715.1	6	MetaCyc: PWY-6731;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-7238	"Starch degradation III";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Sucrose biosynthesis II"
XP_050581542.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050580098.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276	"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways"
XP_050587093.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050578945.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050589918.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050589664.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050581738.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050600141.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_050590803.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050588990.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050579783.1	18	Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"Translation initiation complex formation";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050578959.1	6	KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;MetaCyc: PWY-6749;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_050587342.1	9	KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050597492.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050585435.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050593437.1	7	MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686	"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050590436.1	10	MetaCyc: PWY-5891;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-5895;MetaCyc: PWY-5890;MetaCyc: PWY-7996;MetaCyc: PWY-5892;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5849;MetaCyc: PWY-5844	"Menaquinol-11 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-12 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis"
XP_050586915.1	3	Reactome: R-HSA-196741;Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism"
XP_050596689.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_050596520.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050595219.1	6	MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426	"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050589306.1	37	Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9639288;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-4551638;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-204005;Reactome: R-HSA-191859;Reactome: R-HSA-4570464	"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Amino acids regulate mTORC1";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of chromatin organization proteins";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"COPII-mediated vesicle transport";"snRNP Assembly";"SUMOylation of RNA binding proteins"
XP_050596596.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050592313.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050584578.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050576678.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_050597543.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050578363.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050593949.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050588024.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_050591906.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050581970.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050574535.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050581975.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050584591.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050577670.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050597683.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050582511.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409	"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050577264.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050594867.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050600017.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050599441.1	26	Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082	"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression"
XP_050578687.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-6842	"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II"
XP_050576343.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050579743.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050590553.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050584106.1	5	Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050592601.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050593629.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050592093.1	8	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_050582444.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050579352.1	8	KEGG: 00220+6.3.4.5;Reactome: R-HSA-70635;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;MetaCyc: PWY-5154;MetaCyc: PWY-4984;MetaCyc: PWY-5;MetaCyc: PWY-4983	"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)"
XP_050596441.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050592021.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050573019.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050584660.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050583151.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050590098.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_050585369.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050581240.1	5	MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism";"D-galactose detoxification"
XP_050596946.1	6	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050585169.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050600842.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050593181.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-9609690	"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"HCMV Early Events"
XP_050583670.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050580331.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050590464.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050591040.1	33	Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-69202;Reactome: R-HSA-77075;Reactome: R-HSA-674695	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Transcription of the HIV genome";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin E associated events during G1/S transition";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events"
XP_050596943.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050574463.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050584708.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_050576274.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050594278.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050574532.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050588137.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050593195.1	16	KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.4;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.4;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5749;MetaCyc: PWY-5538;MetaCyc: PWY-5392	"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Itaconate degradation";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II"
XP_050578939.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050592132.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050586863.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050579630.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050573789.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-168325	"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis"
XP_050600254.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system"
XP_050581001.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_050575964.1	12	KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70263	"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis"
XP_050586907.1	7	MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456	"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylketonuria"
XP_050581611.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050599906.1	26	Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847	"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones"
XP_050579316.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050581498.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050595525.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050600072.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050575321.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050590380.1	9	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050597036.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050593191.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_050596334.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050598122.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050600225.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050585380.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050600698.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_050597552.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050580891.1	5	Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050579167.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050590402.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_050599875.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_050573857.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2644606	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050597361.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050588502.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_050585522.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050598305.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_050582692.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_050590112.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050584854.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-72764	"Methylation";"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination"
XP_050597735.1	19	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-8876725;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-3214858;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Protein methylation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050594122.1	5	MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106	"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis"
XP_050581126.1	17	Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-8951664;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-176407	"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Neddylation";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050582161.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050600356.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050596039.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_050585362.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050584231.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050590001.1	52	Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978	"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_050590928.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050583778.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050580815.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276	"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways"
XP_050575268.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050597287.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050595443.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050579302.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050600468.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050581303.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050586093.1	20	MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7338	"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_050589847.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050592125.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050591856.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_050576656.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_050574439.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257	"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Kinesins";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Aggrephagy";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion"
XP_050586567.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050597248.1	12	KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9	"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycogen synthesis";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Glycerolipid metabolism"
XP_050586676.1	6	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway"
XP_050585375.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050596027.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_050582270.1	13	Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509	"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Ion homeostasis";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling"
XP_050574071.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_050592873.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050578070.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_050574390.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_050597046.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050582268.1	13	Reactome: R-HSA-5607763;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-2871809	"CLEC7A (Dectin-1) induces NFAT activation";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization"
XP_050581414.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_050574328.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050598659.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050587700.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050590661.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050577474.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050591788.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050600785.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050584213.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050584073.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050596714.1	10	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"TNFR1-induced NFkappaB signaling pathway";"T cell receptor signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Regulation of TNFR1 signaling";"Human papillomavirus infection"
XP_050575261.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050582409.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050582110.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050598583.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050589883.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_050592837.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050599656.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_050589763.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Recycling pathway of L1";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_050599561.1	8	MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-6142	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050579746.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050585957.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050579153.1	12	MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6277;MetaCyc: PWY-6121	"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Biotin transport and metabolism";"Purine metabolism";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_050575300.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_050580300.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050575826.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050594599.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050596327.1	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Recycling pathway of L1";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050594871.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761	"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_050594643.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598576.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050583444.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050575462.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Activation of RAC1"
XP_050583445.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050585950.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050588078.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050591624.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050587881.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_050582619.1	3	MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_050584170.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050591817.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_050589777.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_050598293.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_050579506.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050583587.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050575355.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050598398.1	5	MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2"
XP_050579877.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050597851.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050584002.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050600429.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050580219.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050597350.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050581664.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050577227.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050597979.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050597676.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050587600.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050593090.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050597221.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050593643.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism"
XP_050593440.1	7	KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"UMP biosynthesis I"
XP_050596809.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-4261	"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerol degradation I"
XP_050583517.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050588456.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050589176.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I"
XP_050592645.1	12	Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050588044.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation"
XP_050590837.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050580172.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050576296.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050587244.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050576190.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050578404.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050587916.1	17	Reactome: R-HSA-200425;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5789	"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Pyruvate metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_050580473.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050582887.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050581939.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050589314.1	52	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-167243	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"FGFR2 alternative splicing";"Dual incision in TC-NER";"Tat-mediated HIV elongation arrest and recovery"
XP_050598390.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_050589415.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050600123.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050592425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050573667.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"Long-term potentiation";"Ion homeostasis";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_050593522.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050592939.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167238	"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050587347.1	9	KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050576593.1	4	KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)"
XP_050588268.1	6	MetaCyc: PWY-7285;Reactome: R-HSA-8868766;MetaCyc: PWY-7286;Reactome: R-HSA-6787450;MetaCyc: PWY-6829;Reactome: R-HSA-6785470	"Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the mitochondrion";"Trna methylation (yeast)";"tRNA processing in the mitochondrion"
XP_050583201.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050586946.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050588910.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099	"Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling"
XP_050599320.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050576391.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906;MetaCyc: PWY-5514;Reactome: R-HSA-70171	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis"
XP_050581267.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050594212.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050573746.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171	"Collagen degradation";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions"
XP_050598727.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050595417.1	4	KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188	"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050597109.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050593621.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050579295.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050597650.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050580201.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_050590567.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050575906.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050581250.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
XP_050589590.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050576640.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050595533.1	15	Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340	"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex"
XP_050579168.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050600444.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_050585425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050591557.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050574944.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050574479.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050586956.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050582967.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050596532.1	12	MetaCyc: PWY-5278;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4	"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Purine metabolism";"Sulfur metabolism";"Transport and synthesis of PAPS";"Sulfate activation for sulfonation";"Sulfur metabolism";"Selenate reduction";"Selenocompound metabolism";"Purine metabolism"
XP_050595539.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337	"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding"
XP_050600754.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050598233.1	11	MetaCyc: PWY-5123;MetaCyc: PWY-7560;MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-6383;MetaCyc: PWY-7102;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6174;MetaCyc: PWY-6859	"Trans, trans-farnesyl diphosphate biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"All-trans-farnesol biosynthesis"
XP_050575428.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050578690.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism"
XP_050589282.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050580644.1	5	Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853	"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)"
XP_050592439.1	4	Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801	"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion"
XP_050585583.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_050596671.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050574918.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050578670.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050576639.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050597621.1	6	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660517;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_050584275.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050592605.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050573076.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050599286.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050592897.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050592033.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050600239.1	8	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050586671.1	8	KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086	"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_050576370.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050585476.1	17	Reactome: R-HSA-9616222;Reactome: R-HSA-2173796;Reactome: R-HSA-113501;Reactome: R-HSA-2559580;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-111448;Reactome: R-HSA-139915;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-2559585;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-8953750;Reactome: R-HSA-1912408	"Transcriptional regulation of granulopoiesis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Activation of NOXA and translocation to mitochondria";"Activation of PUMA and translocation to mitochondria";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Oncogene Induced Senescence";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional Regulation by E2F6";"Pre-NOTCH Transcription and Translation"
XP_050581637.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050583825.1	6	MetaCyc: PWY-5663;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-7442	"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_050598425.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050600469.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050598228.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050584105.1	5	Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050598492.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050581659.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050579555.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050580412.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050600436.1	10	KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050578171.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050596500.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128	"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling"
XP_050596172.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-4641262	"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_050585559.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050594783.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050595516.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050587888.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050598389.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_050596745.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Amino acids regulate mTORC1";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling"
XP_050595077.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050597488.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050586960.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050586140.1	9	MetaCyc: PWY-7533;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842	"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Glutathione metabolism";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II"
XP_050577985.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_050593707.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050581256.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681	"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT"
XP_050595632.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050578379.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050573429.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050579890.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050594331.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055	"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_050600739.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050596894.1	11	Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-76042	"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050588153.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_050586660.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050587292.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050583084.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_050594820.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050575852.1	5	Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_050578300.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_050585538.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_050577364.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050595771.1	2	Reactome: R-HSA-83936;Reactome: R-HSA-2564830	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"Cytosolic iron-sulfur cluster assembly"
XP_050599066.1	26	Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050579456.1	7	KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_050573347.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050586837.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050585000.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_050579936.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050584563.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_050587428.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050600435.1	10	KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050597640.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050592833.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_050579305.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050589310.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050599954.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050596499.1	9	Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174411	"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere"
XP_050594540.1	6	MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism"
XP_050576098.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050575457.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050583848.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050584273.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050582263.1	13	Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509	"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Ion homeostasis";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling"
XP_050575901.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050595998.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050582912.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050586561.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_050598606.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050576334.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050580378.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050578242.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050574651.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050595235.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050573577.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050600929.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_050598210.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050584638.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050574014.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050590512.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050589501.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050586842.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050591905.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050597043.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050592020.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050596502.1	16	Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519	"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression"
XP_050599765.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050600599.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050579083.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050587305.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
XP_050599572.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050595386.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050578937.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050594205.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_050594125.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050598098.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050598772.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050588501.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583177.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050588160.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050593586.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050585664.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050585776.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050586125.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_050579228.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
XP_050590084.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050594904.1	8	Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1	"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis"
XP_050584200.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050577992.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050585199.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050580171.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_050588507.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_050573572.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050583431.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050586674.1	6	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway"
XP_050588064.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050581070.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050591691.1	3	Reactome: R-HSA-4086398;Reactome: R-HSA-392517;Reactome: R-HSA-418457	"Ca2+ pathway";"Rap1 signalling";"cGMP effects"
XP_050587938.1	14	Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-193692	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR"
XP_050585257.1	9	MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52	"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis"
XP_050582464.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050580690.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050600579.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050598035.1	13	Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-416993	"LDL clearance";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors"
XP_050585105.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050584632.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050577340.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-77289	"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050595681.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050594855.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050575455.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050576318.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_050584994.1	16	Reactome: R-HSA-416476;Reactome: R-HSA-8853659;Reactome: R-HSA-194840;Reactome: R-HSA-6811558;Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-1433557;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-2219530;Reactome: R-HSA-114604	"G alpha (q) signalling events";"RET signaling";"Rho GTPase cycle";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-7 signaling";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"Signaling by SCF-KIT";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade"
XP_050595495.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_050584277.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050592064.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050588084.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_050585731.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050573392.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050588015.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050600298.1	11	MetaCyc: PWY-6907;Reactome: R-HSA-901042;Reactome: R-HSA-196819;Reactome: R-HSA-879415;MetaCyc: PWY-6898;Reactome: R-HSA-381426;MetaCyc: PWY-7356;MetaCyc: PWY-6908;Reactome: R-HSA-532668;KEGG: 00730+2.7.6.2;Reactome: R-HSA-8957275	"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Calnexin/calreticulin cycle";"Vitamin B1 (thiamin) metabolism";"Advanced glycosylation endproduct receptor signaling";"Thiamine salvage III";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Thiamine metabolism";"Post-translational protein phosphorylation"
XP_050592584.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_050591148.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050579806.1	18	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050590557.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050587423.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_050583577.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4551638	"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins"
XP_050584625.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050581216.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_050574486.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050596059.1	16	Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-5673001;Reactome: R-HSA-1250342;Reactome: R-HSA-1963640;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-1251985;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986	"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"RAF/MAP kinase cascade";"PI3K events in ERBB4 signaling";"GRB2 events in ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"Nuclear signaling by ERBB4";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2"
XP_050598483.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050595080.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050580086.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050599268.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050591407.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_050595406.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_050589498.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050599318.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050582073.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050584086.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050575768.1	5	Reactome: R-HSA-9033500;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26	"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism"
XP_050583807.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050597595.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050593390.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs"
XP_050572978.1	5	KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_050580498.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050591956.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050584624.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050595304.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050577835.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050591194.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_050575483.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050596559.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_050576691.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050577743.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5696397	"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_050600010.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050579027.1	58	Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5689901;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084	"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Metalloprotease DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_050599849.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050600585.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050594903.1	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_050599474.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050596924.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050574290.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050585430.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-5685938	"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)"
XP_050583967.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050588813.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050577918.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050588075.1	10	Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;KEGG: 00010+2.7.2.3	"Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis"
XP_050580477.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050576270.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050576369.1	4	KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755583	"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_050575645.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050583945.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050575873.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_050585577.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050587461.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050588437.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050575916.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050599284.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583968.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050585882.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050585019.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050592089.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050588316.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane"
XP_050589485.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases"
XP_050576385.1	8	Reactome: R-HSA-71336;Reactome: R-HSA-6791055;MetaCyc: PWY-5723;KEGG: 00030+2.2.1.2;Reactome: R-HSA-163754;MetaCyc: PWY-1861;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462	"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P"
XP_050579504.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050596503.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128	"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling"
XP_050589318.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050593414.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_050599443.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2644606	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050594779.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050600507.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050575825.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050593596.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050584285.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050593481.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050577793.1	8	MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
XP_050574925.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050597782.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_050573505.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_050598961.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050595359.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_050576293.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050593378.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733	"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"UCH proteinases";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_050588685.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-3232142;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SUMOylation of ubiquitinylation proteins";"Neddylation"
XP_050590032.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050583793.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050597486.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050599416.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050586309.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050594357.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050589272.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_050592775.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_050596174.1	22	Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050581777.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050595928.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050581196.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing"
XP_050586840.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050591709.1	4	MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27	"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism"
XP_050575441.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050581156.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_050591649.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050591559.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050586418.1	9	MetaCyc: PWY-5981;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-7385	"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)"
XP_050583384.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050600384.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis"
XP_050581571.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050575963.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050592129.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050573175.1	17	KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-4202;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;MetaCyc: PWY-5532;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6644;Reactome: R-HSA-6798695	"Purine metabolism";"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation"
XP_050576529.1	3	Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144	"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_050588593.1	6	Reactome: R-HSA-6811434;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005	"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport"
XP_050581529.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_050586970.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050585979.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_050592273.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050586846.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050577166.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050584203.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050583259.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050593116.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_050575759.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-2151201	"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050594378.1	11	Reactome: R-HSA-2029485;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4	"Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism"
XP_050587133.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_050596608.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050597740.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050588558.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050594233.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050594460.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050589611.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050573832.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_050576301.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681	"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling"
XP_050583847.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050593785.1	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5358346	"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis"
XP_050588504.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_050594845.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050572989.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_050580984.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050588922.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050584958.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_050581324.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_050588508.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_050597981.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050596579.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050582961.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050573481.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050572991.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_050576689.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050592637.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-77588	"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_050596175.1	22	Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340	"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex"
XP_050574517.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050587553.1	5	KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_050600263.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977	"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_050594933.1	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_050593078.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050594095.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050573880.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050596028.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_050578656.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050580772.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050583409.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
XP_050585358.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050597469.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050576276.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050595463.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050580763.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050587141.1	9	MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;Reactome: R-HSA-112043	"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events"
XP_050581065.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-5122;MetaCyc: PWY-7410;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7102	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)"
XP_050582699.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_050575194.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050594736.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_050585911.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050591785.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050592622.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050573093.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Intraflagellar transport";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050589885.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050596075.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050580722.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050578771.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050584948.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_050583081.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050583580.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050581794.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050594204.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050589372.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4	"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism"
XP_050581296.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_050577136.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050588337.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050581304.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050594678.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050577179.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050596076.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_050576499.1	7	KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7219	"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Drug metabolism - other enzymes";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis"
XP_050597041.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050580114.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050583020.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050573825.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050587950.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050586196.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050597139.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050574559.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050584174.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050576531.1	3	Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426	"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050595025.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_050591472.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050593598.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050587923.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050584173.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050575765.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050578017.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050593637.1	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_050578792.1	3	MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050573038.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050595536.1	15	Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-111465	"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins"
XP_050595831.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-6142	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050596450.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050577682.1	4	KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_050576638.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050580508.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050581670.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050598353.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050588387.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050585108.1	15	Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-912446	"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination"
XP_050582903.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050590508.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050593669.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050597298.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050589715.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050596410.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050598562.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050579397.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050587138.1	9	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-112043	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events"
XP_050574537.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050583954.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050587171.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_050584829.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050583012.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050585666.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_050598588.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050598355.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050580810.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050575866.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050574849.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050580411.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050577856.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050577530.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050582712.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050599732.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_050582150.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_050592761.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050580122.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050582965.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050579997.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050598393.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_050589846.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050597223.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050581877.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050573681.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-442982	"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ion homeostasis";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050587127.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050583780.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_050587880.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_050586027.1	4	Reactome: R-HSA-9610379;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-4570464	"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins"
XP_050595933.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050588339.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050590200.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050592515.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050582837.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_050580396.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579	"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange"
XP_050600499.1	14	KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4	"Glycerophospholipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism"
XP_050598121.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050578762.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050576024.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050580371.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062	"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis"
XP_050577735.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050600258.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050585438.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050590552.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050578219.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050600203.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050573037.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050581020.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050596332.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050592058.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050594633.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors"
XP_050600838.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-73930	"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_050593371.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050594778.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050584282.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050589593.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050582625.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050581953.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050574914.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_050589397.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050573585.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_050596029.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_050593544.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_050597852.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050586405.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050593617.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050584581.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050585815.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050594333.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15	"Synthesis of PA";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism"
XP_050592013.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300	"Aggrephagy";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors"
XP_050573754.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_050587458.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050576187.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050596869.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050599985.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050573227.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050593356.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050583969.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050580231.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_050578660.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050598497.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050589596.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050576738.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050587841.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050582338.1	29	Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-5696395	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER"
XP_050574150.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050587436.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050574284.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050597653.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_050596942.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050597354.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)"
XP_050576954.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050590826.1	9	KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;MetaCyc: PWY-6146;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1	"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism"
XP_050581419.1	18	Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"Translation initiation complex formation";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050593446.1	7	MetaCyc: PWY-5686;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791	"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis III"
XP_050575809.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050585045.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050578009.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050578193.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050593526.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050589843.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050600596.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050588851.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050574377.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050583272.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847	"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones"
XP_050587190.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050585573.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050574543.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050591434.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050586499.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050573768.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050574180.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050599332.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050599218.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508	"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_050579457.1	7	Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-5129	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_050583406.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050588354.1	3	MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway"
XP_050590904.1	10	Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;MetaCyc: PWY-7849;MetaCyc: PWY-7394;KEGG: 00230+3.5.2.17;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;Reactome: R-HSA-975634;Reactome: R-HSA-3000171;Reactome: R-HSA-977225	"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Purine metabolism";"Neutrophil degranulation";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions";"Amyloid fiber formation"
XP_050574587.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050574545.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050574525.1	4	Reactome: R-HSA-9031525;MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-983168	"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Protein ubiquitination";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050574113.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050588353.1	18	Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;MetaCyc: PWY-5084;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-70895;KEGG: 00010+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-71064;KEGG: 00280+1.8.1.4	"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"Glycolysis / Gluconeogenesis";"Lysine degradation";"Glycine, serine and threonine metabolism";"Glycine degradation";"Lysine catabolism";"Valine, leucine and isoleucine degradation"
XP_050587990.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050594637.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050591838.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_050592363.1	13	Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-9020702	"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling"
XP_050580434.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_050579715.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050576760.1	11	Reactome: R-HSA-1660517;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-168138;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-1660516	"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Macroautophagy";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the early endosome membrane"
XP_050580418.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050596589.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440	"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_050598507.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050576694.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050581813.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050580576.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050587033.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050589685.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050582835.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050594756.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050595636.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050580735.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050573883.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050594347.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050596058.1	10	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-382556;Reactome: R-HSA-9648895	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"Recycling of eIF2:GDP";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"ABC-family proteins mediated transport";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_050583615.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050600961.1	14	MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4	"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism"
XP_050583748.1	8	MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_050580376.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050597288.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050588080.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050589984.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050583210.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050599290.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598608.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050580760.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050583591.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050599999.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583768.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050573662.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-936837	"Signaling downstream of RAS mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Ion transport by P-type ATPases"
XP_050594728.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_050573218.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050578373.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050578709.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050590564.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050597225.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050585147.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603	"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"UCH proteinases"
XP_050576938.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050594462.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050596333.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050588385.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_050584657.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050586811.1	7	KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;MetaCyc: PWY-6363	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_050591239.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050578611.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050590657.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050586809.1	7	KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702	"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I"
XP_050575440.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050583458.1	30	Reactome: R-HSA-400253;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1170546;Reactome: R-HSA-69231;Reactome: R-HSA-2122947;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-917937;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-2644607;Reactome: R-HSA-2644606;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902	"Circadian Clock";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Prolactin receptor signaling";"Cyclin D associated events in G1";"NOTCH1 Intracellular Domain Regulates Transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"Iron uptake and transport";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity"
XP_050585048.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050580824.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050598101.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050574503.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050587269.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins"
XP_050593304.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050581032.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050575060.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_050589659.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_050593494.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050595365.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050577252.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050576460.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050585102.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050584577.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050577035.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050586769.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050574602.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050582888.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598610.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050592182.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_050598331.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050584059.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050577899.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_050582630.1	10	Reactome: R-HSA-1855167;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis"
XP_050595534.1	15	Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-195253	"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex"
XP_050582581.1	7	KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_050578288.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050592747.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_050592457.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_050579982.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050575042.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050580142.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050588670.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050573717.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050594733.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050587287.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050597208.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050575260.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050589319.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050577984.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_050579905.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050585778.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_050584524.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_050591781.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050588393.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050588283.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050590929.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050577405.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050574529.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050579209.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050593346.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050598486.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050576335.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050581574.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050584056.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050593454.1	7	KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686	"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050587970.1	3	KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669	"Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_050600114.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_050586822.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050598482.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050576528.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467	"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Kinesins";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs"
XP_050580716.1	5	KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185;MetaCyc: PWY-7210;Reactome: R-HSA-6798695;KEGG: 00230+3.6.1.6	"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"Purine metabolism"
XP_050592212.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-983189	"MHC class II antigen presentation";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Kinesins"
XP_050578007.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050573475.1	8	KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism"
XP_050582117.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050579946.1	20	Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696400	"Polymerase switching";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER"
XP_050589471.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050592312.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050586839.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050597898.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_050587065.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_050597412.1	14	MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050598436.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050573504.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050579786.1	18	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050600395.1	8	KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-2301;KEGG: 00521+5.5.1.4	"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Streptomycin biosynthesis"
XP_050590465.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_050595469.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050589285.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050586831.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050574314.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_050592139.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050585943.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050598020.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050591286.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_050575193.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050583108.1	57	Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-5358346	"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis"
XP_050598850.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050579380.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050598770.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_050598894.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;KEGG: 00520+5.3.1.8;MetaCyc: PWY-6992;MetaCyc: PWY-882	"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Mannitol degradation II";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_050588365.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050588457.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050590150.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_050587435.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_050594379.1	11	Reactome: R-HSA-2029485;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4	"Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism"
XP_050598740.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050600962.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912	"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_050598334.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050600650.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72163	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_050585044.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050578225.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050587260.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050599289.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598550.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050576937.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050577216.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050579312.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)"
XP_050586568.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050588045.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050599920.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050577403.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050586022.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-72203	"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050594267.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050574362.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050583154.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_050591845.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_050591222.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050574036.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_050592960.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050584825.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050594121.1	5	KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;Reactome: R-HSA-532668;MetaCyc: PWY-7918;MetaCyc: PWY-7919	"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)"
XP_050574779.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050581575.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050595576.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050581385.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050586386.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1474228;Reactome: R-HSA-1592389	"Collagen degradation";"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases"
XP_050598034.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-177504	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"LDL clearance";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Retrograde neurotrophin signalling"
XP_050573337.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_050583048.1	5	MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892	"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
XP_050594906.1	8	KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171	"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Glycolysis"
XP_050592459.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050589615.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050590183.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050590153.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_050585433.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482	"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050575020.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050600034.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050582830.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050595641.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050580281.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Regulation of PTEN localization"
XP_050590246.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050578759.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050581236.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050596948.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_050589465.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_050588445.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050580474.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050583859.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050590099.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_050598205.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050581037.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-166208	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"mTORC1-mediated signalling"
XP_050595442.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097	"p38MAPK events";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway"
XP_050577831.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050591007.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050590683.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050583252.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050579230.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_050585121.1	8	KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)"
XP_050586150.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050596536.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050575297.1	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_050597604.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050585929.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_050595638.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050593490.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050590450.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_050594455.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257	"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Degradation of AXIN"
XP_050584899.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_050589503.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050593835.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050594947.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_050599890.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050589312.1	52	Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-167243;Reactome: R-HSA-73780;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-72203;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-674695	"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"FGFR2 alternative splicing";"Dual incision in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Chain Elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events"
XP_050595238.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050599526.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050585020.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050582898.1	11	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation"
XP_050577282.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050586232.1	13	Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101	"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation"
XP_050588030.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050579345.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050581141.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167238	"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050591887.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_050575459.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050578061.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_050589074.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050576620.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050581564.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050573011.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050576602.1	5	MetaCyc: PWY-7279;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-6692	"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation"
XP_050573034.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583970.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050600516.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050573051.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-180910	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs"
XP_050595805.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050581663.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050584223.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050583576.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-180910	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Early Events";"Vpr-mediated nuclear import of PICs"
XP_050598512.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4	"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism"
XP_050587282.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050591235.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism"
XP_050600594.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050598781.1	11	Reactome: R-HSA-877312;Reactome: R-HSA-210990;Reactome: R-HSA-391160;Reactome: R-HSA-9008059;Reactome: R-HSA-389948;Reactome: R-HSA-912694;Reactome: R-HSA-114604;Reactome: R-HSA-432142;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-388841	"Regulation of IFNG signaling";"PECAM1 interactions";"Signal regulatory protein family interactions";"Interleukin-37 signaling";"PD-1 signaling";"Regulation of IFNA signaling";"GPVI-mediated activation cascade";"Platelet sensitization by LDL";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family"
XP_050580450.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050589506.1	4	Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-210991	"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Basigin interactions"
XP_050592137.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050599334.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050586781.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_050585935.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050580914.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050591890.1	52	Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-76071;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73780;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-167243;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-203927;Reactome: R-HSA-75955	"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Chain Elongation";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Dual incision in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation"
XP_050585412.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5362798	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell"
XP_050575454.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_050596909.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050577304.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_050583275.1	26	Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_050592131.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050582112.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050579154.1	7	KEGG: 00230+6.3.3.1;MetaCyc: PWY-6121;Reactome: R-HSA-196780;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;MetaCyc: PWY-6122	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_050597976.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050573322.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050575387.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_050579000.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_050586918.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050597547.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050593029.1	2	Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_050579497.1	6	MetaCyc: PWY-5723;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;Reactome: R-HSA-71336	"Rubisco shunt";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway"
XP_050594539.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050596000.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050577990.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_050581662.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050594178.1	29	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-349425;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-5685942;Reactome: R-HSA-6804760;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693565;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-69541;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Human cytomegalovirus infection";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Autodegradation of the E3 ubiquitin ligase COP1";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Stabilization of p53";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_050598115.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050583963.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050589132.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050600948.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050587993.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_050591972.1	19	MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;Reactome: R-HSA-163765;Reactome: R-HSA-75105	"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis"
XP_050598285.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050595208.1	6	MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426	"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050573731.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050585561.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050581845.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050585575.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050579403.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050574373.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050582415.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050574824.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_050599557.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_050576285.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane"
XP_050600554.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050576020.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050573015.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598728.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050591529.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050580066.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902	"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity"
XP_050582815.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050590231.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050591811.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050591245.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050600300.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_050584281.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050582308.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050589112.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050581133.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050573001.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050580127.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050583782.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_050593083.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050597136.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050586772.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_050595474.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050580687.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050597896.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050586949.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050579044.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050573728.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050595842.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050576224.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050592987.1	52	Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-73780;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-749476;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-76071;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Chain Elongation";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_050589955.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy"
XP_050576196.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050578076.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050600557.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_050587437.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050577509.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050573047.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050580634.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_050584006.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050580222.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
XP_050590158.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050597144.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_050600510.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050587338.1	9	KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050586399.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_050599973.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050589812.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050595363.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_050595215.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050587665.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_050585437.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050575899.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050577820.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050596932.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050572979.1	5	MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_050594863.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050576653.1	13	MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism"
XP_050584055.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050580451.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050574950.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050580988.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050594053.1	22	MetaCyc: PWY-5353;MetaCyc: PWY-7728;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7049;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7053;MetaCyc: PWY-8041;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;MetaCyc: PWY-7606;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7592	"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)"
XP_050591997.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050596109.1	13	MetaCyc: PWY-5392;KEGG: 00620+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-561	"Reductive TCA cycle II";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_050591780.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050582615.1	9	MetaCyc: PWY-5664;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-6703;MetaCyc: PWY-5663;MetaCyc: PWY-7442	"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis"
XP_050595977.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050578952.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation"
XP_050578226.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050585376.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050573219.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050586709.1	11	Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050574261.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050578410.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050585336.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050589879.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Choline catabolism";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_050577566.1	14	MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-6728;Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-3781	"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)"
XP_050582227.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_050581643.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050574639.1	19	Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-381426	"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Platelet sensitization by LDL";"VLDL clearance";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Chylomicron remodeling";"Scavenging by Class F Receptors";"LDL remodeling";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Chylomicron clearance";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050584348.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050592762.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050590323.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050597842.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050592222.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050582468.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050586957.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050593157.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_050574730.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050587956.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050577564.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050580755.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050580462.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050588661.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050579745.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050594250.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050583447.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050580437.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050585930.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_050583594.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050590517.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050594502.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565	"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_050599628.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050590201.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050575443.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050585486.1	8	MetaCyc: PWY-5154;MetaCyc: PWY-7400;Reactome: R-HSA-70635;KEGG: 00250+4.3.2.1;MetaCyc: PWY-4983;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5;MetaCyc: PWY-4984	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Canavanine biosynthesis";"Urea cycle"
XP_050585237.1	10	KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis"
XP_050590030.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism"
XP_050588279.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_050579709.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050584522.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050599850.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050578262.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050597773.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-1632852;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Intraflagellar transport";"MHC class II antigen presentation";"Macroautophagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_050597559.1	11	Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568	"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050598258.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050581222.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050591237.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050578289.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050573735.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050588057.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation"
XP_050584446.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050584929.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050580749.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050575320.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050596387.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050592043.1	6	KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_050574149.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050594507.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050594883.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050594730.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_050596597.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050588770.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050575644.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050573935.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050595754.1	18	Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4	"Acyl chain remodelling of PS";"Synthesis of PA";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism"
XP_050574040.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_050575804.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_050585698.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050590138.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050579386.1	29	Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6796648	"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050597972.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050577171.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade"
XP_050590806.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050587320.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050579391.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050594685.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_050591862.1	24	Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-163359	"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation"
XP_050592596.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050573160.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050586026.1	4	Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-72163	"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway"
XP_050579398.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050592521.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050600382.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050579945.1	6	KEGG: 00900+2.7.1.36;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174	"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)"
XP_050579891.1	13	Reactome: R-HSA-8876725;Reactome: R-HSA-532668;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-9646399;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-382556;Reactome: R-HSA-8866654;Reactome: R-HSA-3371511;Reactome: R-HSA-5689896;Reactome: R-HSA-5689877;Reactome: R-HSA-5678895	"Protein methylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Aggrephagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins";"HSF1 activation";"Ovarian tumor domain proteases";"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis"
XP_050584128.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050579319.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050583586.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050594175.1	7	Reactome: R-HSA-9033241;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-77111;MetaCyc: PWY-5074	"Peroxisomal protein import";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Synthesis of Ketone Bodies";"Mevalonate degradation"
XP_050598429.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050577717.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050575892.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017	"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_050596805.1	6	Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-6118	"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol degradation I";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol-3-phosphate shuttle"
XP_050588266.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050586830.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050588069.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050592437.1	4	Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism"
XP_050574643.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events"
XP_050583785.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050574860.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575	"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling"
XP_050589499.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050584652.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050583083.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050595797.1	31	MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWY-5973;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5994;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-5147;MetaCyc: PWY-7388;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;MetaCyc: PWY-7746;Reactome: R-HSA-75105;Reactome: R-HSA-163765;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-6282;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;MetaCyc: PWY-5367;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWY-4381;MetaCyc: PWY-7858;MetaCyc: PWY-6519	"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"Bryostatin biosynthesis";"Biotin metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis I (plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I"
XP_050579578.1	4	Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050590266.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_050594456.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619	"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN"
XP_050588267.1	26	Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736	"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Kinesins";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors"
XP_050592059.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050583784.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_050585076.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050598151.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050595622.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050574392.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_050583351.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050589392.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050582988.1	4	Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300	"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA"
XP_050595778.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050575966.1	12	Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13	"Gluconeogenesis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism"
XP_050576283.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_050582491.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_050577671.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050598348.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_050595100.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050590063.1	6	Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692	"HCMV Early Events";"HDACs deacetylate histones";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity"
XP_050581688.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050588808.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050599937.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050596152.1	3	KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_050583643.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050597539.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050592301.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050575495.1	5	Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-3371571	"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation"
XP_050585883.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050577027.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050581244.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050582562.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_050591240.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050573343.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_050584017.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050591971.1	19	Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;Reactome: R-HSA-75105;Reactome: R-HSA-163765;KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5690	"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle II (plants and fungi)"
XP_050587619.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050581300.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050593527.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050596614.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050586466.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050589171.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_050584072.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050575715.1	33	Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379	"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events"
XP_050573217.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050596067.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050588070.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050585209.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788;Reactome: R-HSA-3769402;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling";"Deactivation of the beta-catenin transactivating complex";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_050583434.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050576496.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6807505	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
XP_050589571.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050597714.1	10	MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7199;MetaCyc: PWY-7198;Reactome: R-HSA-69205;MetaCyc: PWY-3841;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7187;KEGG: 00670+2.1.1.45	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"One carbon pool by folate"
XP_050591437.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050597426.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050574007.1	16	Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-180585	"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G"
XP_050592932.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050580768.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050583040.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050595898.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050591978.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050598852.1	4	KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_050574013.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050593625.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050574464.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050593179.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-180910	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Vpr-mediated nuclear import of PICs"
XP_050596929.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_050577452.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050581260.1	5	MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821	"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification"
XP_050596438.1	5	KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_050599740.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050594327.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15	"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism"
XP_050581274.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050589953.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050592463.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050587478.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_050583876.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050593797.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_050595027.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050587663.1	5	KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation"
XP_050573645.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001	"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ion homeostasis";"RAF/MAP kinase cascade"
XP_050589566.1	4	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_050580787.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050589151.1	14	MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_050597430.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050584102.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_050575942.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_050573854.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_050573044.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050581594.1	11	KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6549;Reactome: R-HSA-71403;MetaCyc: PWY-7124;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42	"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism"
XP_050586313.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050599847.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050589899.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_050583813.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050593247.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050580574.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050598518.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_050597039.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050599303.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583595.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050590984.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050581978.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050585978.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050581137.1	14	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167242	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_050580106.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050582465.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050586364.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317	"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
XP_050597259.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050599816.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050595129.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"G alpha (i) signalling events";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050575695.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583304.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050574393.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_050598345.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_050583987.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050597237.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050589309.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050577478.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050580725.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050585936.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050595509.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276	"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways"
XP_050574957.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050583246.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4	"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism"
XP_050598771.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050597534.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050592185.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050579640.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050584225.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050596601.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050591632.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050598593.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050593963.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050580785.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050585774.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_050599823.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598289.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050576206.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050592086.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway"
XP_050588154.1	4	MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5	"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism"
XP_050595640.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050581996.1	24	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-5625740;Reactome: R-HSA-2871837;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;Reactome: R-HSA-354192;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 05165+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"CLEC7A (Dectin-1) signaling";"RSK activation";"Regulation of TP53 Degradation";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"RHO GTPases activate PKNs";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Downstream TCR signaling";"Integrin signaling";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"Activation of AKT2";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human papillomavirus infection";"GPVI-mediated activation cascade";"Thermogenesis"
XP_050578940.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050597089.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050598299.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050578400.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050594720.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050574045.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_050588496.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050578352.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050574620.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends"
XP_050585149.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050593200.1	25	Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-381771;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-392451	"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G-protein activation";"Ca2+ pathway";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma"
XP_050595673.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050578739.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_050590216.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050577367.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050589532.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050584954.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050574739.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_050587064.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_050597137.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_050586380.1	10	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome"
XP_050573125.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Nicotinamide salvaging";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
XP_050596999.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050579558.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050583518.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050600152.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050594757.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050592648.1	13	KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-2871796;Reactome: R-HSA-202433;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;Reactome: R-HSA-2871809;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated MAPK activation";"Generation of second messenger molecules";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"FCERI mediated Ca+2 mobilization";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_050577653.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050579459.1	4	Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-166058	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_050574473.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_050577916.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050593459.1	5	MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5686	"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis I"
XP_050573447.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050581439.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_050598747.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050597285.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050580584.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_050588281.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050584827.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050590382.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050582152.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050584104.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_050574039.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050573229.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050573807.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383	"Glycolysis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050574555.1	6	MetaCyc: PWY-2942;MetaCyc: PWY-8088;MetaCyc: PWY-2941;KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;MetaCyc: PWY-5097	"L-lysine biosynthesis III";"Dipicolinate biosynthesis";"L-lysine biosynthesis II";"Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis VI"
XP_050581334.1	7	MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation"
XP_050581512.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050583220.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050574043.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_050585584.1	5	Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_050599219.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050593451.1	7	MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790	"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis II"
XP_050588265.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050597088.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050588048.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_050576316.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050598522.1	14	MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053	"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II"
XP_050589091.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041	"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_050594315.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050596806.1	6	MetaCyc: PWY-4261;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3	"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerophospholipid metabolism"
XP_050580280.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_050578008.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050589135.1	6	Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_050577505.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050599278.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050581514.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453	"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response"
XP_050587268.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_050593372.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_050599494.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050591974.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_050581005.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_050576059.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72662	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Translation initiation complex formation";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_050587522.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050586854.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050595127.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841	"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines"
XP_050578095.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050600309.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050593088.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050577907.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_050581198.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050576447.1	7	MetaCyc: PWY-6351;MetaCyc: PWY-7625;Reactome: R-HSA-1483226;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system"
XP_050593590.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade"
XP_050593452.1	7	MetaCyc: PWY-5686;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10	"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism"
XP_050577908.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence"
XP_050573344.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050581420.1	18	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050599070.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575	"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling"
XP_050577224.1	3	MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12	"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_050594167.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050599354.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Signaling by Hippo";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_050586820.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050588926.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050581257.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_050581625.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050573174.1	17	KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6627;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6620;MetaCyc: PWY-4202;Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;MetaCyc: PWY-5532	"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage III";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Purine salvage";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Nucleoside and nucleotide degradation (archaea)"
XP_050580821.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050591970.1	19	KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5538;MetaCyc: PWY-5392	"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II"
XP_050575798.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_050578365.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050592710.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050593623.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050583015.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050577536.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050576996.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050576532.1	7	Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;MetaCyc: PWY-5265;MetaCyc: PWY-6471;Reactome: R-HSA-446193	"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050577292.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050580087.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050578542.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050586285.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050594438.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050580083.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050573643.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050587302.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050591253.1	16	Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-164939;Reactome: R-HSA-5099900	"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4"
XP_050590060.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050600362.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050594269.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050579809.1	18	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_050584447.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050595444.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050591647.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050581595.1	11	KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7124;MetaCyc: PWY-6969;MetaCyc: PWY-6549	"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III"
XP_050589579.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050574084.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050580143.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050590148.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_050595028.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050592154.1	10	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)"
XP_050594196.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050586765.1	11	MetaCyc: PWY-6606;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6596;MetaCyc: PWY-6999;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6538;MetaCyc: PWY-5695;MetaCyc: PWY-6607;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6608	"Guanosine nucleotides degradation II";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Caffeine metabolism";"Guanosine nucleotides degradation III"
XP_050584886.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050588477.1	7	MetaCyc: PWY-5941;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221	"Glycogen degradation II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)"
XP_050589284.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050587711.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050597398.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050587230.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050584847.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050579569.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050574839.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050590838.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050581855.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_050596179.1	19	KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-7383;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism"
XP_050588870.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050581355.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050586872.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_050577477.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050580500.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050593788.1	7	Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838	"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Activation of SMO"
XP_050583217.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
XP_050598262.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050597238.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050596872.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050581284.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050589068.1	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_050583941.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_050598488.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050584999.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_050575057.1	5	MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-446199;Reactome: R-HSA-4755579	"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ"
XP_050582817.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050579870.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050575116.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination"
XP_050585850.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050583218.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657	"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes"
XP_050583086.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_050582550.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050590308.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_050593269.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer"
XP_050589184.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050594758.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050589448.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553	"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs"
XP_050594176.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050585183.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050581786.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050595466.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050586844.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050584230.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050595661.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050581955.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050591866.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_050591839.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_050588172.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050594615.1	14	Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238	"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050593213.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050584046.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050592083.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050598458.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050587402.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050588087.1	7	MetaCyc: PWY-7886;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-7782	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Synthesis of PC";"Plasmalogen biosynthesis"
XP_050594973.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050583007.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050576901.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050592583.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_050600902.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050582982.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050595407.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_050581699.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050594231.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_050591241.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050588303.1	11	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050589089.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050577628.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050597147.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050581671.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050589052.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050588873.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050576442.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050600483.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111463	"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs"
XP_050598551.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050591287.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_050598970.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050595130.1	3	Reactome: R-HSA-69273;Reactome: R-HSA-418594;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"G alpha (i) signalling events";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_050574753.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_050599845.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050573797.1	15	KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-5723	"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Rubisco shunt"
XP_050584005.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050591112.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050578457.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050581733.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_050588766.1	2	KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384	"Pentose phosphate pathway";"Ethanol oxidation"
XP_050592023.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050580338.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050576456.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050592919.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050580935.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050592901.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050588291.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_050583023.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050590452.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050594463.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050573968.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050597192.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050578589.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050594445.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050597048.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050580170.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system"
XP_050592535.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050574647.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050596727.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050591631.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050589050.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050588016.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050575943.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_050594996.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050584553.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050586856.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050589451.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs"
XP_050579879.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050598333.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050600904.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050588089.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PC"
XP_050592140.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050578353.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050599764.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050581932.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050590440.1	5	Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050595394.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050574443.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050575824.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050580818.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050581429.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_050580311.1	4	Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75	"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis"
XP_050579560.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_050575761.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206	"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha"
XP_050587640.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050587335.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050584970.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_050574352.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050593767.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_050594902.1	8	KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1	"Galactose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis";"Streptomycin biosynthesis"
XP_050595204.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis"
XP_050591113.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050578406.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050581015.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050590509.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050586193.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050595927.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050600006.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050588957.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050580974.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050587661.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_050581965.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050576245.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050592838.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050582816.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050596569.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050578761.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050579185.1	14	MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7279;MetaCyc: PWY-6728;MetaCyc: PWY-3781;MetaCyc: PWY-5690	"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)"
XP_050578266.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050596728.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598769.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_050576070.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050584048.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050600609.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050593862.1	7	Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2660826	"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_050579931.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050588494.1	15	Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585	"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence"
XP_050593082.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050577594.1	12	MetaCyc: PWY-6842;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;MetaCyc: PWY-801;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-6309	"Glutathione-mediated detoxification II";"Tryptophan catabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_050596694.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050593600.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6	"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation"
XP_050584893.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050597825.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050591860.1	24	Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-4086398	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Ca2+ pathway"
XP_050599568.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050591009.1	8	KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609	"Purine metabolism";"Neutrophil degranulation";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III"
XP_050584848.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050573342.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050587884.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050590983.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050595218.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis"
XP_050596656.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_050583052.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050573339.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_050596899.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050583185.1	6	MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6608;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3	"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Purine metabolism"
XP_050589947.1	8	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050597980.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050583550.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050579798.1	18	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050575431.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050580121.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_050574224.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050587913.1	17	MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743	"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle"
XP_050596710.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-72165	"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway"
XP_050597359.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050582695.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_050594234.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_050580126.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050577077.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_050595029.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050573596.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_050577571.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_050597709.1	12	MetaCyc: PWY-5855;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-6708	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_050600950.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050573752.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050596185.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_050586498.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050594044.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_050580310.1	14	KEGG: 00680+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-181;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00670+2.1.2.1;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-1622;MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661	"Methane metabolism";"Folate transformations II (plants)";"Folate polyglutamylation";"Photorespiration ";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I"
XP_050583161.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050576533.1	7	Reactome: R-HSA-4549356;MetaCyc: PWY-6471;Reactome: R-HSA-446193;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;KEGG: 00550+2.7.8.13	"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis"
XP_050595362.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_050588616.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_050581508.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050594243.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_050573323.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050596879.1	5	MetaCyc: PWY-6168;MetaCyc: PWY-5523;MetaCyc: PWY-7863;Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26	"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism"
XP_050588505.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_050586163.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050579842.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050596877.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050587701.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050592402.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_050592135.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050577221.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050577714.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050599336.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050592019.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050591528.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050599037.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050578760.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050596595.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050598657.1	12	Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Rho GTPase cycle";"mTOR signaling pathway";"Relaxin signaling pathway";"G alpha (q) signalling events";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Human papillomavirus infection";"NRAGE signals death through JNK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050582001.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050599982.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050588174.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050590495.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_050593122.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050597731.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_050577133.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050594681.1	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050583292.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_050591622.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050589773.1	7	MetaCyc: PWY-6074;MetaCyc: PWY-2541;Reactome: R-HSA-9022692;KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;Reactome: R-HSA-191273;MetaCyc: PWY-7154	"Zymosterol biosynthesis";"Phytosterol biosynthesis (plants)";"Regulation of MECP2 expression and activity";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis";"Ergosterol biosynthesis II"
XP_050594261.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050575823.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Displacement of DNA glycosylase by APEX1"
XP_050594268.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050588493.1	15	Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128	"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling"
XP_050592094.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050597414.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)"
XP_050592793.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_050596184.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7589	"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Synthesis of PA";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_050574778.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-6798695;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Neutrophil degranulation";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050593234.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_050596328.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Recycling pathway of L1";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050597538.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050583407.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985	"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose"
XP_050591524.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050581513.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050579215.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050587907.1	17	MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Pyruvate metabolism"
XP_050592606.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050587262.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins"
XP_050580893.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4	"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Synthesis of PA";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism"
XP_050592952.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050580435.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050582075.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050589334.1	13	MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Folate transformations II (plants)";"Folate polyglutamylation";"Metabolism of folate and pterines";"One carbon pool by folate";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes"
XP_050574327.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050582189.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050582700.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_050577238.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050576913.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050590540.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050590996.1	7	Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-4086400	"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"Degradation of DVL";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"PCP/CE pathway"
XP_050588622.1	25	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-380270;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-983189	"MHC class II antigen presentation";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Recycling pathway of L1";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Kinesins"
XP_050596081.1	5	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis"
XP_050582530.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050587063.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_050582750.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050591954.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050592192.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050587905.1	17	MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;MetaCyc: PWY-5789;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780	"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism"
XP_050595206.1	4	KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050598380.1	12	Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1	"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Rho GTPase cycle";"G alpha (q) signalling events";"Human cytomegalovirus infection"
XP_050590082.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050598521.1	14	MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_050588506.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050581345.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050591017.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050595639.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050595422.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050585824.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_050598310.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050578273.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050592925.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050583733.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050598031.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050587717.1	17	KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-7115;MetaCyc: PWY-5690;MetaCyc: PWY-7383;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37	"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)"
XP_050584913.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050598861.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5658442	"ER-Phagosome pathway";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"UCH proteinases";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of RAS by GAPs"
XP_050577534.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050593546.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948	"Neutrophil degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants"
XP_050592931.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050596122.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050585366.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050596183.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_050585938.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050578196.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050593115.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050579909.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050598095.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050597610.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_050578161.1	6	KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234;MetaCyc: PWY-6124	"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II"
XP_050584099.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050574514.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_050587108.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_050590494.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050582274.1	13	Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-1489509	"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling"
XP_050574947.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050574922.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_050599316.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_050599930.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050596315.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050595897.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050586016.1	4	Reactome: R-HSA-9610379;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-4570464	"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins"
XP_050585980.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050577251.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050573770.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050579227.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050575461.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050595807.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050583930.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050579359.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050577799.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420	"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi"
XP_050599537.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050580084.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050588076.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050595203.1	6	Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_050600512.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050597290.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050575658.1	6	KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7820	"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)"
XP_050589313.1	52	Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-76071;Reactome: R-HSA-73779;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-749476;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-5617472;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-73780;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-168325	"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA Polymerase III Chain Elongation";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis"
XP_050581351.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050594499.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483	"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1"
XP_050581578.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050578754.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050590119.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050579889.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050581143.1	14	Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238	"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050591713.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050584007.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050586834.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050593044.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_050595187.1	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050580647.1	5	KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88	"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Alanine, aspartate and glutamate metabolism"
XP_050593178.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159227	"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA"
XP_050592303.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050590255.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050586122.1	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_050573973.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050591840.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_050575398.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050574871.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050588307.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_050589957.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050586942.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050587130.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050591506.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_050587779.1	14	MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-6901;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-7003	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol"
XP_050594383.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050589472.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050578270.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050585167.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050578938.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050600264.1	10	Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328	"Galactose catabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_050575465.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050593951.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050574283.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050596693.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050582789.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050575693.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050600787.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050589177.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Stearate biosynthesis I (animals)"
XP_050577295.1	44	Reactome: R-HSA-162658;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-6802952;Reactome: R-HSA-456926;Reactome: R-HSA-1295596;Reactome: R-HSA-5674135;Reactome: R-HSA-5673001;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-8943724;Reactome: R-HSA-5674499;Reactome: R-HSA-8939211;Reactome: R-HSA-5668599;Reactome: R-HSA-445144;Reactome: R-HSA-74749;Reactome: R-HSA-9649948;Reactome: R-HSA-375165;Reactome: R-HSA-982772;Reactome: R-HSA-2559582;Reactome: R-HSA-9635465;Reactome: R-HSA-202670;Reactome: R-HSA-5654726;Reactome: R-HSA-5654727;Reactome: R-HSA-9627069;Reactome: R-HSA-170968;Reactome: R-HSA-2559580;Reactome: R-HSA-112409;Reactome: R-HSA-444257;Reactome: R-HSA-6802946;Reactome: R-HSA-8940973;Reactome: R-HSA-9634638;Reactome: R-HSA-5654733;Reactome: R-HSA-198753;Reactome: R-HSA-6802948;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3371453;Reactome: R-HSA-2559585;Reactome: R-HSA-881907;Reactome: R-HSA-879415;Reactome: R-HSA-5654732;Reactome: R-HSA-6802955	"Golgi Cisternae Pericentriolar Stack Reorganization";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Signaling by BRAF and RAF fusions";"Thrombin signalling through proteinase activated receptors (PARs)";"Spry regulation of FGF signaling";"MAP2K and MAPK activation";"RAF/MAP kinase cascade";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Regulation of PTEN gene transcription";"Negative feedback regulation of MAPK pathway";"ESR-mediated signaling";"RHO GTPases Activate NADPH Oxidases";"Signal transduction by L1";"Signal attenuation";"Signaling downstream of RAS mutants";"NCAM signaling for neurite out-growth";"Growth hormone receptor signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Suppression of apoptosis";"ERKs are inactivated";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR2 signaling";"Regulation of the apoptosome activity";"Frs2-mediated activation";"Oxidative Stress Induced Senescence";"RAF-independent MAPK1/3 activation";"RSK activation";"Signaling by moderate kinase activity BRAF mutants";"RUNX2 regulates osteoblast differentiation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of FGFR4 signaling";"ERK/MAPK targets";"Signaling by high-kinase activity BRAF mutants";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Regulation of HSF1-mediated heat shock response";"Oncogene Induced Senescence";"Gastrin-CREB signalling pathway via PKC and MAPK";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR3 signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050600597.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050586775.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_050588562.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050578097.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050574466.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050595205.1	6	MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952	"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_050575859.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_050582629.1	10	KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369;MetaCyc: PWY-6362;MetaCyc: PWY-6554;MetaCyc: PWY-6361;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;Reactome: R-HSA-1855191	"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus"
XP_050575481.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050575895.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050592891.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050575790.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050580792.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050585327.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050580199.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050588046.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation"
XP_050595032.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050580660.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_050584065.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050576692.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050577467.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex"
XP_050575425.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050582823.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050595893.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050596353.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050581788.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-9627069	"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity"
XP_050580133.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050592421.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050585961.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050585131.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050586075.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050593585.1	5	Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704	"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade"
XP_050586224.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050589523.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050590985.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_050577250.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050593579.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050590662.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_050575437.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050582004.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050586521.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050575432.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050597183.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_050574777.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Neutrophil degranulation";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050593692.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050585055.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050579992.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_050589462.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050575493.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050587301.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050587189.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_050589220.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050592519.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_050591220.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050581243.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050574649.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_050579297.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050573939.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050587456.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050585940.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050599611.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050586849.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050581410.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_050592458.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_050597845.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050578490.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050588282.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis"
XP_050593624.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050583135.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050574547.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050575356.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050594364.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050582713.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050584520.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050591244.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050574522.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-9031525	"Antigen processing: Ubiquitination & Proteasome degradation";"VLDLR internalisation and degradation";"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake"
XP_050580630.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050580031.1	9	Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-69205	"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription"
XP_050578728.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050579775.1	18	Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
XP_050594542.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation"
XP_050578588.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050597563.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation"
XP_050586315.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_050577601.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy"
XP_050585890.1	11	Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6964;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-381	"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)"
XP_050589582.1	9	MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7115	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_050589133.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050590602.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050593211.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050584075.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_050590496.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_050578217.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050583410.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050579708.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050595149.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050582260.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-5607763	"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Ion homeostasis";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation"
XP_050577479.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_050592594.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050582368.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050600663.1	32	Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-77075	"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050591612.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050592668.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050597974.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050578278.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050581287.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050589998.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050573480.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050583614.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050599295.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050574755.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes"
XP_050598382.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_050573646.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050590397.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257	"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Degradation of AXIN"
XP_050589032.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050577168.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade"
XP_050580373.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-198323	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol"
XP_050589732.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050599067.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050578366.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050576189.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050573586.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_050577110.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs"
XP_050575003.1	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
XP_050573232.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050598532.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050581780.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050581171.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050580345.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340	"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation"
XP_050588495.1	15	Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408	"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation"
XP_050598089.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050583277.1	26	Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082	"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression"
XP_050585198.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_050580088.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050581123.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050594604.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050582002.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050573822.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050573571.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_050593075.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050578100.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050579199.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050581687.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050588018.1	12	Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-8941856;Reactome: R-HSA-350054	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway"
XP_050588529.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_050573372.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_050575821.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_050585373.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050579296.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050590561.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050588242.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050581223.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050594329.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587	"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)"
XP_050586871.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050578491.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050585867.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050590190.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050578888.1	42	Reactome: R-HSA-977225;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-427413;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-3214858;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-912446;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-9609690;Reactome: R-HSA-110328;Reactome: R-HSA-5693607;Reactome: R-HSA-171306;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-3214815;Reactome: R-HSA-2299718;Reactome: R-HSA-110329;Reactome: R-HSA-5334118;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-201722;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-9616222	"Amyloid fiber formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"RMTs methylate histone arginines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"Meiotic recombination";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"HCMV Early Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Processing of DNA double-strand break ends";"Packaging Of Telomere Ends";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDACs deacetylate histones";"Condensation of Prophase Chromosomes";"Cleavage of the damaged pyrimidine";"DNA methylation";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Formation of the beta-catenin:TCF transactivating complex";"HDMs demethylate histones";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis"
XP_050600117.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_050588921.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050574157.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-8951664;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246	"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Neddylation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_050584100.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_050574771.1	11	KEGG: 05163+2.7.11.1;Reactome: R-HSA-8866654;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"E3 ubiquitin ligases ubiquitinate target proteins";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Relaxin signaling pathway";"mTOR signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_050576047.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050588050.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_050593950.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050581231.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_050583855.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050599175.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling"
XP_050588497.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050598019.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050575026.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050579586.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_050574495.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system"
XP_050586953.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050589062.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050583449.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050585359.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050579308.1	13	KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9649948	"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling downstream of RAS mutants"
XP_050598462.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050599675.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050596015.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_050585171.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050592393.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050581624.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050585208.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-450520	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA"
XP_050585947.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050587062.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050591013.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702	"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands"
XP_050578275.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050597921.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050593491.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050573400.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_050593457.1	7	MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790	"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis II"
XP_050600865.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050583194.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050586078.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050597675.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050590062.1	6	Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569	"PPARA activates gene expression";"HDACs deacetylate histones";"HCMV Early Events";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_050578261.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_050591008.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050581275.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050591617.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050595476.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050597135.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050574536.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050585865.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_050586123.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050586260.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050578549.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050576595.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_050587255.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_050599923.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050589775.1	5	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway"
XP_050579553.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050579006.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_050579761.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_050584171.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050594824.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_050593614.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050587388.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050577156.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050584202.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050597008.1	7	Reactome: R-HSA-171319;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-606279;Reactome: R-HSA-5689880	"Telomere Extension By Telomerase";"HATs acetylate histones";"UCH proteinases";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere";"Ub-specific processing proteases"
XP_050596870.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050597007.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_050581941.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050573683.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-111932	"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ion homeostasis";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB"
XP_050577113.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050597542.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050596913.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050583549.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050600578.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050580929.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050593739.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050585724.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050581627.1	8	KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-73614;Reactome: R-HSA-6798695;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage"
XP_050579914.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050599412.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050581169.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050580433.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050583990.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050587234.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_050573621.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050595314.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050578159.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_050598546.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050592390.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050595939.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050583831.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050576641.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050579518.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-5685939	"Digestion of dietary carbohydrate";"HDR through MMEJ (alt-NHEJ)"
XP_050599288.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598352.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050596523.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050585856.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050589320.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050584726.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_050594334.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050574622.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050584992.1	16	Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-1433557;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-1266695;Reactome: R-HSA-6811558;Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-194840	"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"Signaling by SCF-KIT";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"Interleukin-7 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent PI3K/Akt signaling";"RET signaling";"G alpha (q) signalling events";"Rho GTPase cycle"
XP_050582146.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_050580674.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050585206.1	14	Reactome: R-HSA-450520;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788;Reactome: R-HSA-3769402;Reactome: R-HSA-141444	"HuR (ELAVL1) binds and stabilizes mRNA";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling";"Deactivation of the beta-catenin transactivating complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050598563.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050583276.1	26	Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519	"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression"
XP_050589842.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050587306.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050586082.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050576439.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050583986.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_050594096.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050590930.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050581668.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050577512.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_050584326.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050592770.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050578356.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050583850.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050595387.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050582855.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050576544.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050596209.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050597423.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_050597537.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050590745.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050596125.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-7384;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-561;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-6728	"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate metabolism";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle"
XP_050597269.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050584659.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050577672.1	56	Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870	"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins"
XP_050579974.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050593245.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050587831.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050592863.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050573620.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050581433.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050574936.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050593675.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050580277.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050579071.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050589972.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050588848.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050596069.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050582666.1	6	Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Triglyceride catabolism";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050597445.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050583779.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_050597371.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050575642.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050582892.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050579400.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050582578.1	11	MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9	"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Starch and sucrose metabolism";"Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_050590728.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050585665.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_050580972.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050583633.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050575000.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050590189.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050575856.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568	"Estrogen-dependent gene expression";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase"
XP_050588034.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation"
XP_050594912.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_050593182.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-168271	"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_050596127.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050576455.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050580417.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_050592090.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway"
XP_050577170.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade"
XP_050595391.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050583861.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050593351.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050598971.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050573611.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050599548.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-166208	"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Amino acids regulate mTORC1";"mTORC1-mediated signalling"
XP_050586141.1	9	MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18	"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450"
XP_050577532.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050595006.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050581034.1	8	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling"
XP_050573377.1	17	Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5696400	"Polymerase switching";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Dual Incision in GG-NER"
XP_050598032.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050578236.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050576199.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050590305.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_050586286.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583152.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050591321.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870	"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins"
XP_050576234.1	11	Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565	"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants"
XP_050585372.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050587853.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_050600924.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050595925.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050579152.1	12	MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.2;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6122	"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine metabolism";"Biotin transport and metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_050586520.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050591448.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050584058.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050577274.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_050600889.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050593683.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050595421.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050583540.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050586675.1	6	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Circadian Clock"
XP_050585429.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)"
XP_050593450.1	7	MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686	"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050575246.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_050577481.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361	"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Neurexins and neuroligins"
XP_050584587.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050594993.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050578377.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050583792.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050585177.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598691.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050597266.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050579689.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050587929.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050573484.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050598722.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050591764.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050585326.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050574091.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050582466.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050589046.1	12	Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"NrCAM interactions";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_050573657.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-111932	"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB"
XP_050578239.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050600066.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050591816.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050579585.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_050580470.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050581940.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050591734.1	16	MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00680+4.2.1.11;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7124;MetaCyc: PWY-5723	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Methane metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Ethylene biosynthesis V (engineered)";"Rubisco shunt"
XP_050574841.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050594943.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_050578538.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_050585073.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050582681.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050593668.1	13	MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism"
XP_050591449.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050582424.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_050576272.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050594419.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050588563.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050581383.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050573776.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050578369.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050592153.1	10	Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756	"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation"
XP_050573938.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050580744.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050597808.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202	"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition"
XP_050600399.1	8	MetaCyc: PWY-2301;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4	"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism"
XP_050585466.1	5	Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000	"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation"
XP_050598981.1	32	Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
XP_050590562.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050583039.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050585075.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050594359.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050574586.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050574475.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_050581122.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050597566.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (s) signalling events"
XP_050573414.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_050594735.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050588923.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050576282.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050583583.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050581617.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050575488.1	14	MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5078;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5076;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5108;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;MetaCyc: PWY-7767	"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"L-isoleucine degradation II";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis IV";"L-leucine degradation III";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis V";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"L-leucine degradation IV (Stickland reaction)"
XP_050584280.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050589954.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050584616.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050575223.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050599540.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Activation of RAC1";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050593895.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_050575435.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050596501.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128	"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling"
XP_050580482.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050585349.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_050599293.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050574117.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050593618.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050587568.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_050576764.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050588837.1	6	Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050593279.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050592644.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050581280.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050592382.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050587039.1	9	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Neddylation"
XP_050584008.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050582705.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050579748.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050596810.1	6	MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3	"Glycerol degradation I";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophospholipid metabolism"
XP_050586110.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050599311.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050600224.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050589036.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050584327.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050592802.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_050592556.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway"
XP_050593787.1	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5358346	"Activation of SMO";"Release of Hh-Np from the secreting cell";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis"
XP_050572977.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050597474.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050598336.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050577756.1	18	MetaCyc: PWY-6545;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_050587453.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050582183.1	24	Reactome: R-HSA-5218921;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"VEGFR2 mediated cell proliferation";"Regulation of TP53 Degradation";"mTOR signaling pathway";"RSK activation";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs";"Activation of AKT2";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Integrin signaling";"PIP3 activates AKT signaling";"Downstream TCR signaling";"Thermogenesis";"GPVI-mediated activation cascade";"Human papillomavirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050581063.1	4	Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247	"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids"
XP_050577906.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_050589279.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050577230.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050585197.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050590441.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_050591525.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050586310.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050583585.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050579019.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_050594434.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050583985.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050575209.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_050579407.1	11	Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-6804114	"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_050585427.1	11	Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236	"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_050596495.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700	"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_050596871.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050583442.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050573370.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050594775.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050586104.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050591176.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050581062.1	4	KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247	"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids"
XP_050586024.1	4	Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-72163	"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway"
XP_050597651.1	3	Reactome: R-HSA-4724325;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265	"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_050583957.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050596853.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050590238.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-180585	"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"UCH proteinases";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"ER-Phagosome pathway";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G"
XP_050597627.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050581463.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050595468.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050597846.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050597747.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050581644.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050590239.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-211733	"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of AXIN";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_050585046.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050584654.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050578029.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050575266.1	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688	"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism"
XP_050587396.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_050600561.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050581604.1	10	MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-6613	"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"One carbon pool by folate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_050579771.1	18	Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050575439.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050580100.1	33	Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638	"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins"
XP_050590192.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050591243.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050590981.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050589129.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050576934.1	8	KEGG: 04926+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050587233.1	3	KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286	"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation"
XP_050582254.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050579995.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050583183.1	6	MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6608;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3	"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Purine metabolism"
XP_050579581.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050573590.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_050576984.1	34	Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-69656;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-69202;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73772	"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin E associated events during G1/S transition";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape"
XP_050575924.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050590433.1	10	MetaCyc: PWY-5890;MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5891;MetaCyc: PWY-5839;Reactome: R-HSA-2142789;MetaCyc: PWY-5895	"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-13 biosynthesis"
XP_050598851.1	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_050583368.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050574360.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050583357.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050597548.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050589280.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050580696.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050584600.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050589061.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736	"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors"
XP_050582469.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050586832.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050583974.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050574584.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_050590835.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700	"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_050585056.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050596960.1	4	Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_050597297.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050575516.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050586314.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050584004.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_050586763.1	11	MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6538;MetaCyc: PWY-6608;MetaCyc: PWY-6607;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-5497;MetaCyc: PWY-6606;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6596	"Inosine 5'-phosphate degradation";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Caffeine metabolism";"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I"
XP_050579647.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050587140.1	9	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-112043	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events"
XP_050597767.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-176407	"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050600576.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_050573198.1	22	MetaCyc: PWY-7035;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041;MetaCyc: PWY-6958;MetaCyc: PWY-7606;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7592;MetaCyc: PWY-7049;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5353;MetaCyc: PWY-7728;MetaCyc: PWY-5080;MetaCyc: PWY-7725	"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050589592.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050574102.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer"
XP_050591987.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050597849.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050590188.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050584283.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050598323.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050580976.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050575025.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050577765.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050600665.1	57	Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-68827	"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Degradation of AXIN";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex"
XP_050589956.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050575309.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_050596073.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050573598.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_050591541.1	7	Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050599817.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050594098.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050591694.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050584609.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050590868.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050585564.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050573517.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050594907.1	8	KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Galactose metabolism";"Starch and sucrose metabolism"
XP_050587291.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050583331.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050597253.1	12	MetaCyc: PWY-7238;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9	"Sucrose biosynthesis II";"Glycogen synthesis";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Galactose metabolism"
XP_050598400.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843	"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation"
XP_050590489.1	11	Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665	"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells"
XP_050597419.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050586427.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050595381.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050596864.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050582890.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050587939.1	14	Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-977225;Reactome: R-HSA-1251985	"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4"
XP_050573877.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_050592416.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050585150.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050590306.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_050589585.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050598886.1	11	MetaCyc: PWY-7456;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;MetaCyc: PWY-5659;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-6992;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7586	"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"GDP-mannose biosynthesis";"Mannitol degradation II";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_050580681.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_050582923.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050594102.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050577898.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_050583999.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_050583182.1	6	MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-7442	"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis"
XP_050582827.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050578098.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050591255.1	3	Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_050598506.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050594541.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050577762.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050576297.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050583791.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050575573.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050600553.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050600320.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_050573582.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_050577331.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050589185.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050584130.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050600729.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050597937.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050598254.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_050591085.1	19	Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423	"Scavenging by Class H Receptors";"Chylomicron clearance";"LDL clearance";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"VLDL clearance";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Chylomicron remodeling";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"VLDL assembly"
XP_050587646.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050574881.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050597343.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050599642.1	4	Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_050578715.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050581140.1	14	Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238	"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050576920.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050586762.1	14	KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6538;MetaCyc: PWY-6608;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-5497;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6606;MetaCyc: PWY-6596	"Purine metabolism";"Inosine 5'-phosphate degradation";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Caffeine metabolism";"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Drug metabolism - other enzymes";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I"
XP_050596984.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_050591513.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050591258.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050583379.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050594461.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050592362.1	13	Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-937072	"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050586825.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050592418.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050576317.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050581461.1	4	MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050585377.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050589952.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_050595746.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050579323.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;MetaCyc: PWY-7511	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination"
XP_050574457.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_050597624.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_050584648.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050597967.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050585200.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050592455.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_050588436.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050574241.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050595532.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716	"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_050593906.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_050594687.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050583781.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050582986.1	4	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37	"DNA methylation";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism"
XP_050581723.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050577897.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_050598531.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050576884.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_050591480.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050598392.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050578332.1	8	KEGG: 04660+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27	"T cell receptor signaling pathway";"Synthesis of PG";"Cardiolipin biosynthesis I";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism"
XP_050588134.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050590632.1	7	KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-71064	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Lysine catabolism"
XP_050594160.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050592894.1	10	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-9635644	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair"
XP_050598547.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050591823.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050589925.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598729.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050593019.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050579807.1	18	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol"
XP_050573184.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation"
XP_050594255.1	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetylglucosamine degradation II"
XP_050575128.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050591821.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050599411.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050589180.1	14	MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041	"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis"
XP_050587606.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex"
XP_050588031.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050576737.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050580730.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050578655.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050593603.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-6837;Reactome: R-HSA-9033241	"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import"
XP_050598560.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050576902.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050592265.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050600960.1	14	MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_050596882.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events"
XP_050575029.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050593150.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050578370.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050598379.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_050591901.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050583864.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050596052.1	6	Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-162594	"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle"
XP_050577838.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050582987.1	4	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37	"DNA methylation";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism"
XP_050596917.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050591872.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050586375.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050592149.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050584612.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050589712.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050582948.1	19	Reactome: R-HSA-202733;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-975634	"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"LDL remodeling";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Chylomicron clearance";"Post-translational protein phosphorylation";"LDL clearance";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"VLDL clearance";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport"
XP_050580506.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050573330.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050577359.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050598069.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050588476.1	7	KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-5941	"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II";"Glycogen degradation II"
XP_050589445.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050580729.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050589612.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050597560.1	11	Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-174437	"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand"
XP_050596918.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050584974.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050591627.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050596329.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050594528.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050583870.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050582795.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050576457.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_050600744.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050580074.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050600310.1	18	Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925	"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG"
XP_050597911.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050590866.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050596344.1	6	Reactome: R-HSA-1369062;Reactome: R-HSA-5684045;Reactome: R-HSA-390247;Reactome: R-HSA-2046105;Reactome: R-HSA-9603798;Reactome: R-HSA-2046106	"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids";"Linoleic acid (LA) metabolism";"Class I peroxisomal membrane protein import";"alpha-linolenic acid (ALA) metabolism"
XP_050588765.1	2	Reactome: R-HSA-71384;KEGG: 00030+1.1.1.47	"Ethanol oxidation";"Pentose phosphate pathway"
XP_050573134.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050589336.1	13	KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909	"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Folate polyglutamylation";"One carbon pool by folate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)"
XP_050580430.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050592953.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050591689.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_050578320.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050573472.1	8	Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism"
XP_050578944.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050588041.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_050598298.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050594978.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050592902.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050594093.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050586372.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527	"Galactose metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation"
XP_050592602.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050592387.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050579292.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050574759.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050574075.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
XP_050577453.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050582607.1	15	Reactome: R-HSA-9665244;Reactome: R-HSA-5637810;Reactome: R-HSA-9665245;Reactome: R-HSA-9634285;Reactome: R-HSA-9665250;Reactome: R-HSA-8863795;Reactome: R-HSA-9665233;Reactome: R-HSA-9665247;Reactome: R-HSA-9665251;Reactome: R-HSA-1227986;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-9664565;Reactome: R-HSA-9665249	"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to lapatinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to afatinib"
XP_050594751.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050584845.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050593558.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation";"MAP2K and MAPK activation"
XP_050597470.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050574840.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583350.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050595500.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER"
XP_050589999.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050596119.1	13	Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00720+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5690	"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)"
XP_050594505.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050578943.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050577769.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050586870.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050599926.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050575430.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050597271.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050591558.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050586387.1	5	MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism"
XP_050583021.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050582395.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050597605.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050581686.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_050585185.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_050599068.1	26	Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression"
XP_050585718.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050585517.1	7	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines"
XP_050599302.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050593697.1	3	KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_050577169.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072	"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050598881.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050583740.1	8	MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_050577237.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050588293.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_050593839.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5972	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_050574434.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050578781.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050574015.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050587267.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_050598097.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050589895.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_050575156.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050596056.1	10	Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72731;Reactome: R-HSA-72702;Reactome: R-HSA-382556;Reactome: R-HSA-9648895	"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition";"ABC-family proteins mediated transport";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_050576284.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050597832.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050600545.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050580658.1	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_050582963.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050586829.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050583871.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050578062.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_050573182.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050573332.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050598309.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050580905.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050577160.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050583405.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050580823.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050597962.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050581007.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_050579166.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050587357.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050589617.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation"
XP_050593529.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050573584.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_050577273.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050578689.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism"
XP_050578798.1	3	MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050596031.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050594426.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050586835.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050596883.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050582856.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050577542.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050595221.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050599629.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050573030.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050575678.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050585061.1	7	Reactome: R-HSA-5696395;Reactome: R-HSA-2173795;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_050589948.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050595128.1	3	Reactome: R-HSA-69273;Reactome: R-HSA-8862803;Reactome: R-HSA-418594	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"G alpha (i) signalling events"
XP_050598024.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050600687.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050574528.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050576526.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050592044.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108	"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050588132.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050582485.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050597874.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050579793.1	18	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
XP_050591447.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050586993.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050582622.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050594856.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050590658.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050580636.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_050593996.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050581101.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050588081.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050574945.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050585350.1	42	Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-3214815;Reactome: R-HSA-2299718;Reactome: R-HSA-110329;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-3214842;Reactome: R-HSA-2559582;Reactome: R-HSA-5334118;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Early Events";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"HDACs deacetylate histones";"Condensation of Prophase Chromosomes";"Cleavage of the damaged pyrimidine";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HDMs demethylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"DNA methylation";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_050597002.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050582116.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050580774.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050585176.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050591370.1	13	MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.66;Reactome: R-HSA-74259;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Purine metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_050585253.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_050583853.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050599803.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050584823.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050588628.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050582793.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050574361.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050591633.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050598022.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050579844.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050587911.1	17	MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;MetaCyc: PWY-5789;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743	"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle"
XP_050597072.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050575502.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_050579165.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050594928.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310	"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway"
XP_050573647.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952	"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions"
XP_050580717.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050577839.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050582416.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050589383.1	9	Reactome: R-HSA-9657050;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-110357	"Defective OGG1 Localization";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Displacement of DNA glycosylase by APEX1"
XP_050595419.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_050577921.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050586297.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Activation of RAC1";"Nephrin family interactions";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_050589042.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050573588.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_050584248.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050578295.1	5	Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)"
XP_050586175.1	7	KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2	"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism"
XP_050595211.1	6	MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_050574353.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050599480.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_050578748.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050590438.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050577350.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane"
XP_050573124.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050581971.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050592929.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050600602.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050584643.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_050592304.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050580657.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050586509.1	10	MetaCyc: PWY-4321;MetaCyc: PWY-6536;KEGG: 00410+2.6.1.19;KEGG: 00250+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;MetaCyc: PWY-5022;Reactome: R-HSA-916853;MetaCyc: PWY-6537	"L-glutamate degradation IV";"4-aminobutanoate degradation III";"beta-Alanine metabolism";"Alanine, aspartate and glutamate metabolism";"Butanoate metabolism";"4-aminobutanoate degradation I";"Propanoate metabolism";"4-aminobutanoate degradation V";"Degradation of GABA";"4-aminobutanoate degradation II"
XP_050588066.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050595262.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050584486.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050580831.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050589872.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050575498.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050588390.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_050590839.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050584937.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_050578027.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050590503.1	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_050578541.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050589591.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050581789.1	8	Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs"
XP_050588058.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation"
XP_050599400.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050578277.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050590999.1	7	Reactome: R-HSA-4641258;Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598	"Degradation of DVL";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins"
XP_050597092.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050592597.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050574112.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050597196.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050579584.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_050584605.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050577693.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-2514853	"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Synthesis of PC";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes"
XP_050592468.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050578099.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050600390.1	12	KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6683	"Purine metabolism";"Selenocompound metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Selenate reduction";"Sulfur metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Sulfite oxidation III";"Assimilatory sulfate reduction III"
XP_050593616.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050600715.1	11	Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-68962	"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex"
XP_050581505.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050584054.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050590808.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050600240.1	8	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050586465.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-6798695	"WNT ligand biogenesis and trafficking";"Neutrophil degranulation"
XP_050583466.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050593027.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050588036.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050577694.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Synthesis of PC";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation"
XP_050591423.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050596842.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050573334.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050595779.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050596604.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_050583629.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends"
XP_050585400.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050580358.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050598760.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_050590203.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_050578088.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050594538.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364	"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_050584049.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050592918.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050595480.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050573984.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050581565.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050578520.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050597286.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050587270.1	31	MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWY-5147;MetaCyc: PWY-7388;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-5973;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-5994;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-7663;MetaCyc: PWY-8012;MetaCyc: PWY-6282;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-7746;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-7858;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-5367	"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis I (plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Cis-vaccenate biosynthesis";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Pederin biosynthesis";"";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis"
XP_050577632.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050579311.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_050579595.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050585879.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050575460.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050574016.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050595840.1	17	MetaCyc: PWY-7383;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-6969	"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_050575263.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050592239.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050591615.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050581460.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050595112.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-6922	"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_050589534.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050576660.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050582576.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050577294.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050600839.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-110357	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1"
XP_050596885.1	19	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-8876725;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-3214858;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Protein methylation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_050600355.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050576541.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_050580826.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050576332.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050599615.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050582222.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050573028.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050580485.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050573668.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-111932	"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB"
XP_050578368.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050575427.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050588782.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050594603.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050600505.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050598605.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050580168.1	12	KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857	"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Methane metabolism";"Adlupulone and adhumulone biosynthesis"
XP_050593836.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription"
XP_050587842.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050585581.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050574331.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050581276.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050595464.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050598257.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050584728.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050589041.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050584228.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050590191.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050588678.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050583783.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_050573671.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982	"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ion homeostasis";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050578951.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050584544.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050589337.1	13	MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9	"Folate polyglutamylation";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"One carbon pool by folate"
XP_050574657.1	17	Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-1834949;Reactome: R-HSA-2559586;Reactome: R-HSA-3270619;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565	"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Cytosolic sensors of pathogen-associated DNA";"DNA Damage/Telomere Stress Induced Senescence";"IRF3-mediated induction of type I IFN";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050592990.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_050578453.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_050583743.1	8	MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Cholesterol biosynthesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_050599935.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050586910.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050591841.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_050594211.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050586838.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050588668.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050585221.1	33	Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-159227	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA"
XP_050583448.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050589136.1	6	MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism"
XP_050579382.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation"
XP_050590627.1	4	Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-379716	"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation"
XP_050592186.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050576144.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050575633.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050584900.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_050588116.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050592501.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_050593151.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050598397.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_050573018.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050599634.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050587664.1	5	MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22	"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_050598231.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050592874.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050576340.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050580659.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_050596906.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050581719.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050578026.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050586464.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050595213.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis"
XP_050574445.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483	"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Aggrephagy";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs"
XP_050579017.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_050577249.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050586961.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050598734.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050575910.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050582902.1	11	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302	"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway";"p38MAPK events";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation"
XP_050582896.1	11	Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway";"p38MAPK events";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Thermogenesis"
XP_050591714.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050592066.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050578362.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050592937.1	15	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167200	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050573874.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_050578734.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_050588874.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050573936.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050576392.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;Reactome: R-HSA-70171	"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis"
XP_050593488.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_050587834.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050585465.1	5	Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221	"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of MAPK pathway"
XP_050582007.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050575354.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050582479.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050576965.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050588564.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050581657.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050593066.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050583147.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050598209.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050590677.1	13	Reactome: R-HSA-1257604;Reactome: R-HSA-165159;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-9639288;Reactome: R-HSA-5674400	"PIP3 activates AKT signaling";"mTOR signalling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"Amino acids regulate mTORC1";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_050581220.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050582412.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050582586.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050581047.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_050593485.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050590424.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050584585.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050595306.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-201722	"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_050588780.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_050575902.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050586789.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_050600815.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050580415.1	6	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050588534.1	5	KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_050581268.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_050598356.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050595753.1	18	MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Synthesis of PA";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism"
XP_050589779.1	5	Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050586526.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050573483.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050588280.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050590573.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050595093.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050575467.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050593458.1	7	KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5686	"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis I"
XP_050576761.1	11	Reactome: R-HSA-1660516;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-109704;Reactome: R-HSA-168138;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660517	"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade";"Macroautophagy";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane"
XP_050573348.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050592420.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050595913.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050579557.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050574583.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050589388.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050574052.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050574912.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050575030.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050591527.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050593874.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050598711.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050586300.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753	"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions"
XP_050579592.1	15	Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-9603505;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167246	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"NTRK3 as a dependence receptor";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_050583901.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050577770.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050591236.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050577742.1	3	Reactome: R-HSA-202433;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Generation of second messenger molecules";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050596449.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050592985.1	83	Reactome: R-HSA-1963642;Reactome: R-HSA-2428933;Reactome: R-HSA-5654689;Reactome: R-HSA-8875555;Reactome: R-HSA-5654712;Reactome: R-HSA-1257604;Reactome: R-HSA-8853334;Reactome: R-HSA-1250196;Reactome: R-HSA-5663213;Reactome: R-HSA-5655302;Reactome: R-HSA-1963640;Reactome: R-HSA-8856828;Reactome: R-HSA-9034864;Reactome: R-HSA-5655253;Reactome: R-HSA-5654699;Reactome: R-HSA-5654719;Reactome: R-HSA-180336;Reactome: R-HSA-210993;Reactome: R-HSA-8853338;Reactome: R-HSA-5654695;Reactome: R-HSA-5654727;Reactome: R-HSA-8983432;Reactome: R-HSA-912526;Reactome: R-HSA-375165;Reactome: R-HSA-5654720;Reactome: R-HSA-182971;Reactome: R-HSA-5654706;Reactome: R-HSA-74749;Reactome: R-HSA-9028335;Reactome: R-HSA-2871796;Reactome: R-HSA-74751;Reactome: R-HSA-180292;Reactome: R-HSA-9607240;Reactome: R-HSA-1839117;Reactome: R-HSA-1295596;Reactome: R-HSA-9645135;Reactome: R-HSA-5654693;Reactome: R-HSA-9026519;Reactome: R-HSA-388841;Reactome: R-HSA-389359;Reactome: R-HSA-5654732;Reactome: R-HSA-1433559;Reactome: R-HSA-1236382;Reactome: R-HSA-1433557;Reactome: R-HSA-5654700;Reactome: R-HSA-2029482;Reactome: R-HSA-5654710;Reactome: R-HSA-8851805;Reactome: R-HSA-5654733;Reactome: R-HSA-179812;Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-2730905;Reactome: R-HSA-109704;Reactome: R-HSA-2179392;Reactome: R-HSA-5654726;Reactome: R-HSA-391160;Reactome: R-HSA-5654688;Reactome: R-HSA-9027284;Reactome: R-HSA-2871809;Reactome: R-HSA-8875360;Reactome: R-HSA-912631;Reactome: R-HSA-5654704;Reactome: R-HSA-354194;Reactome: R-HSA-112412;Reactome: R-HSA-186763;Reactome: R-HSA-2424491;Reactome: R-HSA-5673001;Reactome: R-HSA-9028731;Reactome: R-HSA-5655291;Reactome: R-HSA-8865999;Reactome: R-HSA-8851907;Reactome: R-HSA-8875656;Reactome: R-HSA-8853659;Reactome: R-HSA-8856825;Reactome: R-HSA-9664565;Reactome: R-HSA-9634285;Reactome: R-HSA-5637810;Reactome: R-HSA-983695;Reactome: R-HSA-6807004;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-167044	"PI3K events in ERBB2 signaling";"SHC-related events triggered by IGF1R";"PI-3K cascade:FGFR1";"MET activates RAP1 and RAC1";"FRS-mediated FGFR4 signaling";"PIP3 activates AKT signaling";"Signaling by FGFR3 fusions in cancer";"SHC1 events in ERBB2 signaling";"RHO GTPases Activate WASPs and WAVEs";"Signaling by FGFR1 in disease";"GRB2 events in ERBB2 signaling";"Clathrin-mediated endocytosis";"Activated NTRK3 signals through RAS";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR2";"SHC-mediated cascade:FGFR4";"SHC1 events in EGFR signaling";"Tie2 Signaling";"Signaling by FGFR3 point mutants in cancer";"PI-3K cascade:FGFR2";"Negative regulation of FGFR2 signaling";"Interleukin-15 signaling";"Interleukin receptor SHC signaling";"NCAM signaling for neurite out-growth";"PI-3K cascade:FGFR4";"EGFR downregulation";"FRS-mediated FGFR3 signaling";"Signal attenuation";"Activated NTRK2 signals through PI3K";"FCERI mediated MAPK activation";"Insulin receptor signalling cascade";"GAB1 signalosome";"FLT3 Signaling";"Signaling by cytosolic FGFR1 fusion mutants";"Spry regulation of FGF signaling";"STAT5 Activation";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through RAS";"Costimulation by the CD28 family";"CD28 dependent Vav1 pathway";"Negative regulation of FGFR3 signaling";"Regulation of KIT signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by SCF-KIT";"FRS-mediated FGFR2 signaling";"Regulation of actin dynamics for phagocytic cup formation";"PI-3K cascade:FGFR3";"MET activates RAS signaling";"Negative regulation of FGFR4 signaling";"GRB2 events in EGFR signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"PI3K Cascade";"EGFR Transactivation by Gastrin";"Negative regulation of FGFR1 signaling";"Signal regulatory protein family interactions";"SHC-mediated cascade:FGFR1";"Erythropoietin activates RAS";"FCERI mediated Ca+2 mobilization";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of signaling by CBL";"SHC-mediated cascade:FGFR3";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"SOS-mediated signalling";"Downstream signal transduction";"DAP12 signaling";"RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3";"Signaling by FGFR4 in disease";"MET activates PTPN11";"MET activates PI3K/AKT signaling";"MET receptor recycling";"RET signaling";"Cargo recognition for clathrin-mediated endocytosis";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by EGFRvIII";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Negative regulation of MET activity";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signalling to RAS"
XP_050591822.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050597927.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337	"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding"
XP_050573672.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_050592433.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050575375.1	13	Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427	"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation"
XP_050585777.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050578752.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050590451.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_050593134.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050577929.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050586779.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_050597138.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_050576936.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_050590480.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050591424.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050597541.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050581067.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050574211.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050589720.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050576985.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050583522.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050586019.1	4	Reactome: R-HSA-9610379;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-4570464	"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins"
XP_050578333.1	8	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;KEGG: 04660+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-5668	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"T cell receptor signaling pathway";"Synthesis of PG";"Cardiolipin biosynthesis I"
XP_050594955.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_050573597.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_050577490.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050587418.1	5	Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-162710	"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050592374.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050596905.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_050578307.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050595934.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050591707.1	4	Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642	"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation"
XP_050575898.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598701.1	12	KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482	"Human cytomegalovirus infection";"G alpha (q) signalling events";"mTOR signaling pathway";"Relaxin signaling pathway";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"NRAGE signals death through JNK";"Human papillomavirus infection";"DCC mediated attractive signaling";"G alpha (12/13) signalling events"
XP_050600586.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050599680.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050585305.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050575247.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050590809.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050573656.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066	"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_050584205.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050591157.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050574419.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867	"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex"
XP_050586947.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050581217.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050583812.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050585578.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050585053.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050579298.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050592796.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_050574010.1	179	Reactome: R-HSA-5684264;Reactome: R-HSA-3769402;Reactome: R-HSA-179409;Reactome: R-HSA-5654726;Reactome: R-HSA-72706;Reactome: R-HSA-180585;Reactome: R-HSA-2559582;Reactome: R-HSA-5607761;Reactome: R-HSA-174490;Reactome: R-HSA-8875360;Reactome: R-HSA-9645460;Reactome: R-HSA-936964;Reactome: R-HSA-2691232;Reactome: R-HSA-5654732;Reactome: R-HSA-5685942;Reactome: R-HSA-2644606;Reactome: R-HSA-6804760;Reactome: R-HSA-209560;Reactome: R-HSA-1253288;Reactome: R-HSA-6782135;Reactome: R-HSA-5654733;Reactome: R-HSA-2565942;Reactome: R-HSA-5693607;Reactome: R-HSA-3134975;Reactome: R-HSA-6783310;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5689901;Reactome: R-HSA-450302;Reactome: R-HSA-8849469;Reactome: R-HSA-937072;Reactome: R-HSA-168928;Reactome: R-HSA-2122947;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-8863795;Reactome: R-HSA-168927;Reactome: R-HSA-5610785;Reactome: R-HSA-209543;Reactome: R-HSA-5678895;Reactome: R-HSA-5689896;Reactome: R-HSA-69541;Reactome: R-HSA-175474;Reactome: R-HSA-4641258;Reactome: R-HSA-9013507;Reactome: R-HSA-5654727;Reactome: R-HSA-174184;Reactome: R-HSA-1358803;Reactome: R-HSA-110314;Reactome: R-HSA-3785653;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-1236974;Reactome: R-HSA-5696400;Reactome: R-HSA-69481;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-975144;Reactome: R-HSA-110312;Reactome: R-HSA-174113;Reactome: R-HSA-1169408;Reactome: R-HSA-5610783;Reactome: R-HSA-5656169;Reactome: R-HSA-8948747;Reactome: R-HSA-937042;Reactome: R-HSA-936440;Reactome: R-HSA-8856828;Reactome: R-HSA-9604323;Reactome: R-HSA-6791226;Reactome: R-HSA-9613829;Reactome: R-HSA-5676590;Reactome: R-HSA-168638;Reactome: R-HSA-69017;Reactome: R-HSA-2173795;Reactome: R-HSA-5696397;Reactome: R-HSA-202424;Reactome: R-HSA-192823;Reactome: R-HSA-9014325;Reactome: R-HSA-937039;Reactome: R-HSA-5693565;Reactome: R-HSA-8941858;Reactome: R-HSA-2122948;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-1799339;Reactome: R-HSA-2894862;Reactome: R-HSA-9615710;Reactome: R-HSA-5357905;Reactome: R-HSA-174048;Reactome: R-HSA-3322077;Reactome: R-HSA-9633012;Reactome: R-HSA-983168;Reactome: R-HSA-205043;Reactome: R-HSA-1236382;Reactome: R-HSA-8854050;Reactome: R-HSA-72764;Reactome: R-HSA-5358346;Reactome: R-HSA-2979096;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-445989;Reactome: R-HSA-9646399;Reactome: R-HSA-5362768;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-975163;Reactome: R-HSA-8939236;Reactome: R-HSA-5675221;Reactome: R-HSA-2173796;Reactome: R-HSA-174154;Reactome: R-HSA-6807004;Reactome: R-HSA-69601;Reactome: R-HSA-532668;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-8866652;Reactome: R-HSA-211733;Reactome: R-HSA-2408557;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-912631;Reactome: R-HSA-2173791;Reactome: R-HSA-9013973;Reactome: R-HSA-975956;Reactome: R-HSA-5655862;Reactome: R-HSA-5357956;Reactome: R-HSA-977225;Reactome: R-HSA-917937;Reactome: R-HSA-110320;Reactome: R-HSA-2559580;Reactome: R-HSA-201681;Reactome: R-HSA-5687128;Reactome: R-HSA-156827;Reactome: R-HSA-68827;Reactome: R-HSA-156902;Reactome: R-HSA-901032;Reactome: R-HSA-2467813;Reactome: R-HSA-8876493;Reactome: R-HSA-2672351;Reactome: R-HSA-9010553;Reactome: R-HSA-5675482;Reactome: R-HSA-2559585;Reactome: R-HSA-162588;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-6804757;Reactome: R-HSA-975957;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-2173788;Reactome: R-HSA-1295596;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5689877;Reactome: R-HSA-349425;Reactome: R-HSA-937041;Reactome: R-HSA-4641263;Reactome: R-HSA-1169091;Reactome: R-HSA-9637628;Reactome: R-HSA-5696395;Reactome: R-HSA-72689;Reactome: R-HSA-450408;Reactome: R-HSA-182971;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-8866654;Reactome: R-HSA-5205685;Reactome: R-HSA-975110;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-9636383;Reactome: R-HSA-4608870;Reactome: R-HSA-9033241	"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Deactivation of the beta-catenin transactivating complex";"APC-Cdc20 mediated degradation of Nek2A";"Negative regulation of FGFR1 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Vif-mediated degradation of APOBEC3G";"Senescence-Associated Secretory Phenotype (SASP)";"Dectin-1 mediated noncanonical NF-kB signaling";"Membrane binding and targetting of GAG proteins";"InlB-mediated entry of Listeria monocytogenes into host cell";"Alpha-protein kinase 1 signaling pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Negative regulation of FGFR3 signaling";"HDR through Homologous Recombination (HRR)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of TP53 Activity through Methylation";"NF-kB is activated and signals survival";"Downregulation of ERBB4 signaling";"Dual incision in TC-NER";"Negative regulation of FGFR4 signaling";"Regulation of PLK1 Activity at G2/M Transition";"Processing of DNA double-strand break ends";"Regulation of innate immune responses to cytosolic DNA";"Fanconi Anemia Pathway";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Metalloprotease DUBs";"activated TAK1 mediates p38 MAPK activation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"NOTCH1 Intracellular Domain Regulates Transcription";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Downregulation of ERBB2 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"GLI3 is processed to GLI3R by the proteasome";"p75NTR recruits signalling complexes";"Defective CFTR causes cystic fibrosis";"Ovarian tumor domain proteases";"Stabilization of p53";"Assembly Of The HIV Virion";"Degradation of DVL";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR2 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downregulation of ERBB2:ERBB3 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Myoclonic epilepsy of Lafora";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"ER-Phagosome pathway";"Dual Incision in GG-NER";"G2/M Checkpoints";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Translesion synthesis by REV1";"SCF-beta-TrCP mediated degradation of Emi1";"ISG15 antiviral mechanism";"Degradation of GLI2 by the proteasome";"Termination of translesion DNA synthesis";"Regulation of PTEN localization";"IRAK2 mediated activation of TAK1 complex";"Negative regulators of DDX58/IFIH1 signaling";"Clathrin-mediated endocytosis";"Negative regulation of NOTCH4 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Chaperone Mediated Autophagy";"NIK-->noncanonical NF-kB signaling";"NOD1/2 Signaling Pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downstream TCR signaling";"Viral mRNA Translation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK1 recruits IKK complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of RUNX3 expression and activity";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Neddylation";"CLEC7A (Dectin-1) signaling";"SRP-dependent cotranslational protein targeting to membrane";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Late endosomal microautophagy";"Regulation of TNFR1 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Glycogen synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Antigen processing: Ubiquitination & Proteasome degradation";"NRIF signals cell death from the nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Eukaryotic Translation Termination";"Hedgehog ligand biogenesis";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Aggrephagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of MAPK pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of MET activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Circadian Clock";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Selenocysteine synthesis";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of signaling by CBL";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TICAM1-dependent activation of IRF3/IRF7";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translesion synthesis by POLK";"TNFR1-induced NFkappaB signaling pathway";"Amyloid fiber formation";"Iron uptake and transport";"Translesion Synthesis by POLH";"Oxidative Stress Induced Senescence";"TCF dependent signaling in response to WNT";"MAPK6/MAPK4 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"CDT1 association with the CDC6:ORC:origin complex";"Peptide chain elongation";"ER Quality Control Compartment (ERQC)";"Separation of Sister Chromatids";"InlA-mediated entry of Listeria monocytogenes into host cells";"Stimuli-sensing channels";"Regulation of expression of SLITs and ROBOs";"Regulation of necroptotic cell death";"Oncogene Induced Senescence";"Budding and maturation of HIV virion";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Regulation of TP53 Degradation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Downregulation of TGF-beta receptor signaling";"Spry regulation of FGF signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Josephin domain DUBs";"Autodegradation of the E3 ubiquitin ligase COP1";"IKK complex recruitment mediated by RIP1";"Regulation of FZD by ubiquitination";"Activation of NF-kappaB in B cells";"Modulation by Mtb of host immune system";"Formation of Incision Complex in GG-NER";"Formation of a pool of free 40S subunits";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"EGFR downregulation";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"E3 ubiquitin ligases ubiquitinate target proteins";"Pink/Parkin Mediated Mitophagy";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Prevention of phagosomal-lysosomal fusion";"Asymmetric localization of PCP proteins";"Peroxisomal protein import"
XP_050600242.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050582296.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I"
XP_050588446.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050590614.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050600209.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050578176.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050596077.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_050577715.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050582934.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050584121.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050575051.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050587300.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050574718.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050579664.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050592866.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050590828.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050591115.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050573659.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982	"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ion homeostasis";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050581399.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050579797.1	18	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
XP_050580505.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050593645.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001	"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050591403.1	11	MetaCyc: PWY-5686;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7400	"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)"
XP_050584451.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050594362.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050584991.1	16	Reactome: R-HSA-416476;Reactome: R-HSA-8853659;Reactome: R-HSA-194840;Reactome: R-HSA-1266695;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-2219530;Reactome: R-HSA-114604	"G alpha (q) signalling events";"RET signaling";"Rho GTPase cycle";"Interleukin-7 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade"
XP_050596409.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050581035.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-166208	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"mTORC1-mediated signalling"
XP_050589587.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050578774.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050594634.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695;Reactome: R-HSA-2162123	"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
XP_050591985.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050596733.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050586867.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050592785.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050597590.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050585145.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_050591359.1	4	KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;MetaCyc: PWY-5331	"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Taurine biosynthesis I"
XP_050587457.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050573625.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050573216.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_050580478.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050586708.1	11	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_050596072.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050597200.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050588906.1	6	KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23	"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism"
XP_050588444.1	9	KEGG: 00270+2.6.1.5;KEGG: 00950+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00130+2.6.1.5	"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_050590894.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050597614.1	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_050597446.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050598476.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_050581791.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome"
XP_050588040.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy"
XP_050600743.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050582498.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-2122947;Reactome: R-HSA-381340	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Generic Transcription Pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation"
XP_050586855.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050598892.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050576233.1	11	Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530	"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_050588913.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050589174.1	14	MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041	"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis"
XP_050575480.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050575385.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050583902.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_050590210.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6782210	"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050595774.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050585144.1	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050577244.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050581952.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050577797.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050584922.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050578116.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050578323.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050590863.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_050579163.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050592758.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050585072.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050589730.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050593445.1	7	MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686	"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050589731.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050591555.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050585946.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050599514.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050599292.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598528.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050596313.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050587899.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050589470.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050594930.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395	"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER"
XP_050578306.1	14	MetaCyc: PWY-5690;MetaCyc: PWY-3781;MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-7279;MetaCyc: PWY-6728;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00190+1.3.5.1	"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Oxidative phosphorylation"
XP_050594550.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050576768.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050585858.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050592759.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_050582628.1	10	MetaCyc: PWY-6554;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050572993.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_050593353.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050581817.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050590601.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050594905.1	8	Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050600728.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050579973.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050589586.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050584517.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050599565.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050590269.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050598026.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050592499.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_050577157.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050577881.1	33	Reactome: R-HSA-113418;Reactome: R-HSA-69656;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-69202;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-8939236;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-69231;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"Formation of the Early Elongation Complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Cyclin E associated events during G1/S transition";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin D associated events in G1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_050591836.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050600717.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300	"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA"
XP_050573751.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Meiotic synapsis";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_050585168.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050579580.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050576388.1	5	MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation"
XP_050596721.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050579329.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050584769.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050581336.1	7	MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-7586	"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_050589321.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050598493.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_050588671.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050595000.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_050590467.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050598682.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050591789.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050582473.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050577821.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050592302.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050573117.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065676;Reactome: R-HSA-3065678	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_050582267.1	13	Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Ca2+ pathway"
XP_050582305.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050584212.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050594152.1	4	KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis"
XP_050573136.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050598287.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050572994.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-434316	"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_050591556.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050581430.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050587994.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_050593248.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050575256.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050600470.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050578271.1	5	KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050577576.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050575489.1	14	MetaCyc: PWY-7767;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5108;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5104;KEGG: 00280+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103	"L-leucine degradation IV (Stickland reaction)";"Pantothenate and CoA biosynthesis";"L-valine degradation II";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-leucine degradation III";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"L-isoleucine degradation II";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III"
XP_050573161.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050594754.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050573591.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_050582828.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050580759.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050574494.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_050590031.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_050589164.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I"
XP_050594281.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050582076.1	2	Reactome: R-HSA-2129379;Reactome: R-HSA-189085	"Molecules associated with elastic fibres";"Digestion of dietary carbohydrate"
XP_050584598.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050597810.1	4	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Neurotransmitter clearance"
XP_050593021.1	5	Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877	"Aggrephagy";"Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs"
XP_050583238.1	14	MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism"
XP_050593184.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-180746	"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein"
XP_050594790.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68689	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex"
XP_050578965.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050576453.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050594114.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-8853884	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX"
XP_050584222.1	4	Reactome: R-HSA-3299685;Reactome: R-HSA-2393930;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Phosphate bond hydrolysis by NUDT proteins";"Purine metabolism";"Pyrimidine metabolism"
XP_050588847.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050586284.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050593199.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050593528.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050584195.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_050592943.1	9	Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-6807505	"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes"
XP_050575468.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_050582621.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050579217.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050588934.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050592842.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050574275.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050591151.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050581731.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050580179.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050579789.1	18	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_050592394.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050584980.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050581201.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050595992.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050585898.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050575827.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050594459.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050582791.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050596082.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050598716.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050591147.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050584443.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050597004.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050598946.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050597182.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_050577219.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050588809.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050591706.1	4	MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895	"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism"
XP_050595982.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050597431.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050575466.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050595868.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_050586120.1	6	MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_050582460.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050579396.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050574460.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP"
XP_050578120.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050595388.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050592309.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050586654.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050596657.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_050583554.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050589530.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050593382.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330	"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_050579880.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050578078.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050589658.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_050597608.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050600491.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050590791.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_050599270.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050586173.1	7	KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis"
XP_050585021.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050582539.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050590102.1	3	Reactome: R-HSA-8964046;Reactome: R-HSA-8866376;Reactome: R-HSA-8866427	"VLDL clearance";"Reelin signalling pathway";"VLDLR internalisation and degradation"
XP_050574315.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050599749.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050588052.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation"
XP_050582057.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050598092.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050594574.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050581266.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_050573674.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-3371571	"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"HSF1-dependent transactivation"
XP_050582487.1	29	Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-5696395	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER"
XP_050598350.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050583772.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation"
XP_050592527.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"mTORC1-mediated signalling";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_050591859.1	24	Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"Ca2+ pathway";"G-protein activation";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events"
XP_050595642.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050592471.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050584770.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050585382.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050578040.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050579750.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_050584579.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050578174.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050597181.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_050597197.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events"
XP_050597471.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050593256.1	5	MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Vitamin B6 metabolism"
XP_050580113.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050589322.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050586331.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050583329.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050586382.1	10	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_050584257.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050577269.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050591385.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050587565.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_050596405.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050592642.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050578072.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_050595999.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050579225.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050582408.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050596398.1	5	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_050584928.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_050592927.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050574540.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050596350.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050591981.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050583382.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050577600.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy"
XP_050591150.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050582250.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome"
XP_050579985.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_050575377.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_050586860.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050595803.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050587445.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_050589665.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050582154.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_050593373.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_050575132.1	7	MetaCyc: PWY-6385;Reactome: R-HSA-5633231;MetaCyc: PWY-5265;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471;Reactome: R-HSA-446193	"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050589449.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178	"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans"
XP_050592057.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050589844.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050581061.1	4	Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9	"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism"
XP_050594412.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_050574345.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050592766.1	20	Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5651801	"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Polymerase switching";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair"
XP_050598068.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050597561.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050581721.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050577763.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050599413.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050584512.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050585921.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050595447.1	4	MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism"
XP_050595768.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050586968.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050598536.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_050598424.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050573969.1	9	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol"
XP_050585846.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_050589181.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050575473.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050600577.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050591794.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050576390.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6	"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_050573228.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050599155.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"PKA activation"
XP_050585050.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598206.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050574096.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050589060.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719	"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors"
XP_050595445.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050596927.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050596020.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050574072.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
XP_050583744.1	8	MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_050577824.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050593123.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050578075.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050592764.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050587109.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_050599846.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598776.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15	"Synthesis of PA";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism"
XP_050574504.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050580606.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050579913.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_050591406.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_050590805.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050589167.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_050588461.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_050584175.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050583835.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050593530.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050597195.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_050599472.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050575692.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050590511.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050578154.1	7	MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-7282	"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_050581922.1	24	Reactome: R-HSA-5674400;Reactome: R-HSA-9634635;Reactome: R-HSA-389357;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-5625740;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-1257604	"Constitutive Signaling by AKT1 E17K in Cancer";"Estrogen-stimulated signaling through PRKCZ";"CD28 dependent PI3K/Akt signaling";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"RSK activation";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"Thermogenesis";"GPVI-mediated activation cascade";"Human papillomavirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of AKT2";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"Integrin signaling";"Downstream TCR signaling";"PIP3 activates AKT signaling"
XP_050584374.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"Protein ubiquitination";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
XP_050593193.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050592036.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050574820.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_050574038.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050591984.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050580226.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_050593449.1	7	MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Drug metabolism - other enzymes"
XP_050575283.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050592417.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050581658.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050591333.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050577270.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050583804.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050584444.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050598290.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050593079.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050597829.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050577475.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050599415.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050573579.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_050600519.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_050576303.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681	"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling"
XP_050588632.1	11	Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-163680	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AMPK inhibits chREBP transcriptional activation activity"
XP_050596568.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050575207.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050588175.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_050584349.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050575301.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_050576586.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050587434.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_050598387.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_050596690.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_050594606.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050594642.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050590919.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050591771.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050584614.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050588156.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_050578240.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050590630.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050600011.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050579993.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050581844.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050590230.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050589275.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050585829.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_050578006.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050598224.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050600081.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050586680.1	6	Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050584588.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050600364.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050586969.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050593148.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050591952.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852	"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy"
XP_050589782.1	5	Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16	"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway"
XP_050594479.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_050592460.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050590950.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_050578658.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-264870	"COPI-mediated anterograde transport";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_050595384.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050579220.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050593974.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050573195.1	26	Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-8866654;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-4615885;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-174414	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"E3 ubiquitin ligases ubiquitinate target proteins";"G1/S-Specific Transcription";"Polymerase switching";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"SUMOylation of DNA replication proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere"
XP_050582618.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050586712.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050600637.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_050578375.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050595151.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050579520.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050596349.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_050582364.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050594729.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_050578302.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_050591699.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050585962.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050595631.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050591155.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050587067.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_050598110.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050585261.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050573594.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050573970.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050573369.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-432722	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis"
XP_050573410.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050584519.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050590592.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-901032	"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)"
XP_050588630.1	11	Reactome: R-HSA-9614657;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"FOXO-mediated transcription of cell death genes";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050584497.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050581195.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination"
XP_050593155.1	6	MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050588090.1	7	MetaCyc: PWY-7886;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-7782	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Synthesis of PE";"Synthesis of PC";"Plasmalogen biosynthesis"
XP_050595663.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050583874.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_050573836.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050597199.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050576205.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050581018.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050574915.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050576555.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050599276.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050592436.1	4	Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801	"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion"
XP_050589901.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69091	"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching"
XP_050594457.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619	"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN"
XP_050577900.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_050575390.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050595535.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337	"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding"
XP_050577991.1	14	Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-110312	"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1"
XP_050587830.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050593480.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050596149.1	3	MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9	"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050596875.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050578192.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050579712.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050575962.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_050576339.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050589891.1	6	Reactome: R-HSA-6811440;Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050575399.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050593560.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952	"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions"
XP_050581411.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_050600949.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050584894.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050575501.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_050573641.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_050573666.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-3371571	"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Ion homeostasis";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"HSF1-dependent transactivation"
XP_050574629.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050593460.1	5	MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-7790	"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine biosynthesis";"UMP biosynthesis II"
XP_050580302.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050578153.1	7	MetaCyc: PWY-6121;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_050587397.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_050574911.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_050597145.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050573648.1	4	MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis"
XP_050594750.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050588673.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050580227.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050585240.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050598354.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050591599.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050576286.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050584816.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_050587471.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050587692.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050585012.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_050587284.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050575639.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-200425	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism"
XP_050593917.1	3	Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050600583.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050587973.1	57	Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323	"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling"
XP_050592088.1	8	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050573176.1	17	Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6620	"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine salvage";"Adenine and adenosine salvage III";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage"
XP_050591614.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050596221.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050574956.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050584782.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121	"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI"
XP_050584000.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050586965.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050590327.1	34	Reactome: R-HSA-4551638;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025	"SUMOylation of chromatin organization proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation"
XP_050594043.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_050588027.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation"
XP_050576076.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_050578686.1	17	Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5656169	"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Termination of translesion DNA synthesis"
XP_050590428.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050591650.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050579907.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050587598.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050584445.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050575429.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050587392.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_050586472.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050581249.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317	"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
XP_050579406.1	11	Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-3214858;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082	"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"RMTs methylate histone arginines";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Estrogen-dependent gene expression";"RORA activates gene expression"
XP_050593468.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050573326.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050573513.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978	"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"UCH proteinases";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_050589716.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050585553.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050583563.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_050584351.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050573204.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902	"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity"
XP_050595131.1	3	Reactome: R-HSA-8862803;Reactome: R-HSA-418594;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"G alpha (i) signalling events";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050597713.1	10	MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7199;MetaCyc: PWY-7198;Reactome: R-HSA-69205;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-3841;MetaCyc: PWY-7187;KEGG: 00670+2.1.1.45	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"G1/S-Specific Transcription";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"One carbon pool by folate"
XP_050577817.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050591458.1	18	MetaCyc: PWY-6545;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_050592466.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_050599450.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_050573231.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050573300.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_050578960.1	6	KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6749;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
XP_050578751.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050580753.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050599967.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050591779.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050598878.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_050587846.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050574454.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050572996.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_050581246.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050594716.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050599210.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050579388.1	27	Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-167242;Reactome: R-HSA-72187;Reactome: R-HSA-77588;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-77595;Reactome: R-HSA-975957;Reactome: R-HSA-8851708;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-975956;Reactome: R-HSA-167158	"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA 3'-end processing";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Processing of Intronless Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Signaling by FGFR2 IIIa TM";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the HIV-1 Early Elongation Complex"
XP_050588732.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050577620.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_050583387.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050599896.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050582214.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050583589.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050596477.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050594336.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050586471.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050578783.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050579799.1	18	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050582886.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050595383.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050588033.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050589778.1	5	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway"
XP_050585797.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism"
XP_050593230.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050584509.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050585571.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050598381.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050592595.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050581511.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050575436.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050577826.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050581252.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_050589709.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050592964.1	17	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050577268.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050595658.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050579639.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050590518.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050579875.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050595209.1	6	Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_050573658.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-111932	"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ion homeostasis";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB"
XP_050578930.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050596852.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050594050.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050584888.1	4	Reactome: R-HSA-8950505;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response"
XP_050583332.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050584211.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050585424.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050574351.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050582321.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050591608.1	3	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-948021	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification"
XP_050578269.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050588332.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane"
XP_050583819.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_050578083.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050584626.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050584051.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050600018.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050573897.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050574474.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events"
XP_050597915.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
XP_050592871.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050595530.1	15	Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-196299	"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade"
XP_050595420.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760	"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation"
XP_050573733.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050578918.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050573333.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050577858.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050598887.1	4	KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609;Reactome: R-HSA-446199;MetaCyc: PWY-6129	"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis"
XP_050588569.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050586865.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050576141.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_050588243.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050574459.1	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP"
XP_050598288.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050587345.1	9	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol"
XP_050582489.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-73762	"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation"
XP_050580230.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_050580646.1	5	Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853	"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)"
XP_050593834.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050599843.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050581353.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050584221.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050596150.1	3	MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581	"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050594557.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_050588607.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050574442.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690	"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"MHC class II antigen presentation";"Gap junction assembly";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"HCMV Early Events"
XP_050589647.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_050574037.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050598201.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
XP_050583142.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050585352.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5676590	"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"UCH proteinases";"Degradation of AXIN";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling"
XP_050592989.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_050591886.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_050581510.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050583732.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050581435.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050598071.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_050590575.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state"
XP_050585378.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050577901.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_050593740.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050583070.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050597611.1	4	Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_050594780.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050592982.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050598286.1	12	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"Human papillomavirus infection";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Thermogenesis";"G alpha (q) signalling events";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Rho GTPase cycle"
XP_050589968.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050592560.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050590419.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050578091.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050593672.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis"
XP_050584540.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050593738.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050577006.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050583994.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050592061.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050588086.1	7	MetaCyc: PWY-7782;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-3385	"Plasmalogen biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I"
XP_050584172.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050597649.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_050599442.1	26	Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847	"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones"
XP_050597780.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166	"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2"
XP_050598367.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_050577800.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399	"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_050599872.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050580424.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579	"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange"
XP_050584719.1	19	Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-194840;Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-5663213;Reactome: R-HSA-8950505;Reactome: R-HSA-2029482;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5625970	"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"Myogenesis";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"Rho GTPase cycle";"Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"RHO GTPases Activate WASPs and WAVEs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of actin dynamics for phagocytic cup formation";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases activate KTN1"
XP_050579967.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050573624.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050590823.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050587261.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins"
XP_050578497.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_050589276.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050600662.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050600256.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050593222.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050576150.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050593507.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050574001.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050598383.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_050585683.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-381676	"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"PKA activation";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_050591621.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050590834.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes"
XP_050590898.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050584510.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050582979.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050584219.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_050589845.1	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism"
XP_050599964.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050589522.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-196299	"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade"
XP_050589157.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_050593483.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050592992.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_050589496.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050584098.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050574627.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050595634.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050588366.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050592469.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_050577896.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_050587283.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050579527.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_050597527.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050584260.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050587827.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050578702.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050598088.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050581635.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050595938.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050592123.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050585699.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050594417.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-113507	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation"
XP_050588996.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_050573684.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ion homeostasis";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors"
XP_050590760.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050573644.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001	"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ion homeostasis";"RAF/MAP kinase cascade"
XP_050573937.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050575288.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050585709.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050597626.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050582423.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_050593120.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050589977.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050586264.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050573092.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_050576321.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050597535.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050573386.1	17	Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135	"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER"
XP_050597270.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050583989.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050587203.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050595317.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050597222.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050595740.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050580765.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050593149.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050594948.1	8	MetaCyc: PWY-1861;Reactome: R-HSA-6791461;KEGG: 00030+5.3.1.6;Reactome: R-HSA-5659996;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Rubisco shunt";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism"
XP_050588453.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050577768.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050594689.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050577917.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050586776.1	5	Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050587517.1	40	Reactome: R-HSA-5617472;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis"
XP_050582442.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050580577.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050574207.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050590893.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_050581265.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_050580761.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050576071.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050592289.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_050585775.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_050578350.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050592787.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050581602.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_050592475.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation"
XP_050591704.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050596991.1	33	Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168271	"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_050573831.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_050595570.1	7	MetaCyc: PWY-6363;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_050592450.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050600393.1	12	MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25	"Selenate reduction";"Sulfur metabolism";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Sulfur metabolism";"Purine metabolism";"Selenocompound metabolism";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Purine metabolism"
XP_050592189.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050581292.1	56	Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174154	"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"UCH proteinases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin"
XP_050600062.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050588778.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050587620.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050577794.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050587475.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676	"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle"
XP_050576394.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_050578799.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_050574282.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_050588867.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050592039.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050598768.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_050593551.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"Neutrophil degranulation";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_050592384.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050579524.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-5685939	"Digestion of dietary carbohydrate";"HDR through MMEJ (alt-NHEJ)"
XP_050576266.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-9013973	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7"
XP_050588644.1	14	MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Methane metabolism"
XP_050577819.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050595896.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050600555.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050588157.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_050587921.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050591912.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050584526.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050596182.1	29	Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-5696395	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER"
XP_050590220.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_050580655.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_050574654.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050592119.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050587996.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_050587328.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050587132.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_050578104.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050586853.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050591628.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050591782.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050596385.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_050583516.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050590506.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_050597572.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;MetaCyc: PWY-7511	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination"
XP_050578411.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050592375.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050577569.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_050600749.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050581233.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_050589354.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050586270.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050594832.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_050588088.1	7	MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886	"Plasmalogen biosynthesis";"Synthesis of PC";"Synthesis of PE";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_050595890.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050578826.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050583795.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050573304.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection"
XP_050596898.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_050581548.1	20	Reactome: R-HSA-165159;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-166208;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571	"mTOR signalling";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"PIP3 activates AKT signaling";"Human papillomavirus infection";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Thermogenesis";"PI3K-Akt signaling pathway";"mTORC1-mediated signalling";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Macroautophagy";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation"
XP_050600381.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050592098.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050577134.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050594433.1	26	Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833	"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Aggrephagy";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly"
XP_050577828.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050600603.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050593601.1	20	KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-6920	"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)"
XP_050582989.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_050577115.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_050583976.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_050576135.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050598513.1	14	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416	"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_050576302.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662	"Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism"
XP_050574943.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050580313.1	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781;Reactome: R-HSA-6787450	"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_050584147.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050579810.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050586938.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050583822.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050578101.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050587129.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050577323.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050591825.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050589706.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050597304.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050598523.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_050576990.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-176407	"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050594150.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050592084.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_050582552.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050597473.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050578284.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050584589.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050581696.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050585110.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050595311.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050584016.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050590013.1	8	Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis"
XP_050589154.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_050584936.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050596359.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050582140.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050586174.1	7	KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis"
XP_050582265.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-5607763	"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation"
XP_050593838.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_050597881.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050583274.1	26	Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408	"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation"
XP_050595253.1	4	KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188	"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050600238.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_050590326.1	34	Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025	"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation"
XP_050581878.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050573066.1	8	MetaCyc: PWY-66;Reactome: R-HSA-6787639;MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-5740	"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-fucose biosynthesis";"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis"
XP_050580913.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050583905.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050584783.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_050590804.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050578280.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050587279.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050584126.1	7	MetaCyc: PWY-5695;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596	"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I"
XP_050600610.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050579990.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis"
XP_050579321.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050594284.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050583846.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050592264.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050591238.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050590401.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050584597.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050587878.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_050584442.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050578357.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050591826.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050585574.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050588139.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050582272.1	13	Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-5607763	"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation"
XP_050596575.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050582480.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050593436.1	7	KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686	"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050577465.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination"
XP_050579926.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050579787.1	18	Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050599544.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Amino acids regulate mTORC1";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling"
XP_050583747.1	8	MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Cholesterol biosynthesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_050585716.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050586972.1	18	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Protein ubiquitination";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins"
XP_050589810.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050591000.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-201688;Reactome: R-HSA-201681	"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT"
XP_050592591.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-392451	"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"G-protein activation";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma"
XP_050588617.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_050591250.1	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;Reactome: R-HSA-1362409;MetaCyc: PWY-7250	"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_050575278.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050586304.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050594800.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050590010.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5083629	"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_050581496.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050584324.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050593657.1	18	MetaCyc: PWY-6642;MetaCyc: PWY-6643;MetaCyc: PWY-7383;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00950+2.6.1.1	"(R)-cysteate degradation";"Coenzyme M biosynthesis II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Arginine and proline metabolism";"Isoquinoline alkaloid biosynthesis"
XP_050592386.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050573655.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-111932	"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB"
XP_050583123.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050595931.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050576763.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050575298.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050588171.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050577644.1	12	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167200	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050574462.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050592263.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_050598312.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050580093.1	33	Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-191859	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"snRNP Assembly"
XP_050573990.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;Reactome: R-HSA-5609977	"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_050581509.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050588963.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_050578561.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050574518.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_050575479.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050572995.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050588049.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_050576961.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050589729.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050597984.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050582966.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050590113.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050597302.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050591846.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_050585859.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050589051.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050598615.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050575307.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_050578534.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050584649.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050589053.1	12	Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324	"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_050599179.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"PKA activation"
XP_050573413.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050596902.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050578749.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050594209.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050575277.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050581139.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167287	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery"
XP_050589027.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050589389.1	12	MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-6708;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5857	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_050588559.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050573214.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_050575254.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050583049.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050594666.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050580471.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050580229.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050598423.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050588363.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050589130.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050578941.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050585498.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050584204.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050592055.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050578801.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050594844.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050596730.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050584376.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"Protein ubiquitination";"Degradation of AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
XP_050599209.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050574680.1	4	MetaCyc: PWY-7805;Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_050598854.1	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_050594343.1	10	Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-983168	"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050599848.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050595318.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050588539.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_050575499.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050587288.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050585051.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050578585.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_050593152.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050592092.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050584844.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050593567.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_050586774.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling"
XP_050585557.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050598426.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050575259.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050573749.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490	"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen degradation"
XP_050596478.1	9	Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-69205	"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription"
XP_050593404.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050597536.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050580273.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_050574396.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_050594857.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050577818.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050578197.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050599163.1	11	Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170670	"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase inhibitory pathway"
XP_050577830.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050586633.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_050578272.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050575028.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050581232.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_050576281.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050594570.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050585689.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050592784.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_050578267.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050597477.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050589848.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_050580204.1	7	Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168333	"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050574477.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050577771.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050597850.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050594860.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050593644.1	10	KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-6842	"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II"
XP_050573183.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050583843.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050579681.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_050592810.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_050577449.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050582792.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050588769.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050590205.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_050580145.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050578942.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050590595.1	5	Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-381038	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes"
XP_050588577.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050589667.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050592792.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_050582510.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050599317.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050580274.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_050574955.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050598759.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_050600570.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050586951.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050596916.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050577220.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050574009.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-8951664;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243	"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Neddylation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery"
XP_050599870.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050582390.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050581632.1	24	Reactome: R-HSA-2730905;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-165158;Reactome: R-HSA-354192;Reactome: R-HSA-5625740;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;Reactome: R-HSA-444257	"Role of LAT2/NTAL/LAB on calcium mobilization";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"GPVI-mediated activation cascade";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Downstream TCR signaling";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Activation of AKT2";"Integrin signaling";"RHO GTPases activate PKNs";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"Human cytomegalovirus infection";"CLEC7A (Dectin-1) signaling";"mTOR signaling pathway";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"RSK activation"
XP_050583761.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050575081.1	5	KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)"
XP_050598039.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050597415.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050587508.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050584933.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_050585494.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050593049.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_050590725.1	57	Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-8951664	"Degradation of DVL";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"UCH proteinases";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"G2/M Checkpoints";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neddylation"
XP_050582030.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050579892.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050598342.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_050596567.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050586659.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050586073.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050598822.1	23	Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391	"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Ca2+ pathway";"G-protein activation";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling"
XP_050600816.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050590555.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050588815.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050580773.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_050576480.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050573192.1	13	MetaCyc: PWY-6842;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1	"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism"
XP_050600534.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050592795.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_050594508.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050594596.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050587574.1	7	Reactome: R-HSA-6804114;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription"
XP_050587566.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050589447.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050576161.1	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_050594503.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_050582969.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050582414.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050578498.1	9	Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050581459.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050576542.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_050583356.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050586936.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050579526.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer"
XP_050578268.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050581202.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050595094.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050576441.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050590492.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050592448.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050588675.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050597960.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_050590510.1	4	Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
XP_050578450.1	11	Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050578405.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050593036.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050594337.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050588992.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_050582046.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050588219.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814	"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes"
XP_050585845.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050573091.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_050580441.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050590403.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_050582499.1	7	Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-2122947	"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050590813.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050595308.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050598261.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050573595.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050585410.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050589373.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_050594097.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050593562.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_050582367.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050587959.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050597550.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050584573.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_050589850.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050574209.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050583944.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050589967.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050579773.1	18	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_050597040.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050582957.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050590047.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050582698.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_050575762.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)"
XP_050586881.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050589903.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69166	"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate"
XP_050575339.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_050585707.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050573796.1	15	MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Purine metabolism"
XP_050592356.1	13	Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-450302	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation"
XP_050590560.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050578081.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050585204.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050590888.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870	"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"UCH proteinases";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Degradation of DVL";"Asymmetric localization of PCP proteins"
XP_050579244.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050579811.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050574815.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050580004.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050581856.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_050577568.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_050584013.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050587839.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050588938.1	3	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_050588733.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050584646.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050599473.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050596734.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050583481.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050584644.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050592299.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050598609.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050586864.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050578241.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050597422.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050590554.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050585695.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050593523.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050590206.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_050600569.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050584967.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_050592258.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050574751.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050579888.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050572990.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events"
XP_050588692.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050587533.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050599314.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050580128.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050597587.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050574946.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050587451.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050577483.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361	"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Neurexins and neuroligins"
XP_050581678.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050583427.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050580080.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050598690.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050598778.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050589224.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050576294.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050598277.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050600836.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-73930	"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_050590383.1	9	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_050584214.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050594471.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050600397.1	8	MetaCyc: PWY-4661;Reactome: R-HSA-1855183;MetaCyc: PWY-6372;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-2301	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis"
XP_050595305.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-201722	"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_050592260.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_050598371.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_050593047.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_050583438.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050577321.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050588383.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050597301.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050594607.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050584096.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050600388.1	12	KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550	"Selenocompound metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Sulfur metabolism";"Sulfur metabolism";"Selenate reduction";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"
XP_050573130.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050583114.1	7	KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_050589393.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_050599439.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050586299.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-186763	"Nephrin family interactions";"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction"
XP_050598152.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_050585523.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050580934.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050576292.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050589726.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050599223.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781	"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"PPARA activates gene expression"
XP_050584677.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_050590611.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050599075.1	26	Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_050598372.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_050585937.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050581019.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050598311.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050586754.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050588138.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050594187.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050590488.1	11	Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507	"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_050574444.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050593482.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050589148.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050596522.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050575442.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050598545.1	14	KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051	"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I"
XP_050587460.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050592840.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8948700	"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_050597916.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050598430.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050596021.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050597734.1	19	Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-8876725;Reactome: R-HSA-3214858;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957	"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Protein methylation";"RMTs methylate histone arginines";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050575774.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050573341.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_050583973.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050596071.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050578114.1	4	MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621	"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism"
XP_050596519.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050595439.1	5	Reactome: R-HSA-4420097;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-171007	"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"p38MAPK events"
XP_050590006.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050596907.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050591570.1	18	KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4	"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_050575456.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050574861.1	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050575018.1	6	KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52	"Vitamin B6 metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_050598783.1	11	Reactome: R-HSA-389948;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-877312;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-909733;Reactome: R-HSA-432142;Reactome: R-HSA-114604;Reactome: R-HSA-912694	"PD-1 signaling";"Signal regulatory protein family interactions";"PECAM1 interactions";"Interleukin-37 signaling";"Regulation of IFNG signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"Interferon alpha/beta signaling";"Platelet sensitization by LDL";"GPVI-mediated activation cascade";"Regulation of IFNA signaling"
XP_050573966.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050594668.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050596636.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050583521.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050585901.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_050573651.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802946	"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants"
XP_050573856.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050579788.1	18	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling"
XP_050589450.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs"
XP_050599614.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050581234.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050573570.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050581125.1	17	Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-983168	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050587867.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050587071.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_050575977.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050585173.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050594953.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050580095.1	33	Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379	"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events"
XP_050599567.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050587668.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050586653.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050588051.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050577181.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050578130.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050593552.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608	"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation"
XP_050588047.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050584718.1	19	Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-983231;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-428543	"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"Factors involved in megakaryocyte development and platelet production";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"Myogenesis";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1"
XP_050577977.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050589657.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_050583153.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_050598962.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050580937.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050582153.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_050586833.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050573788.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_050575775.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050583278.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050592841.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050581064.1	13	MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-5122;MetaCyc: PWY-7410;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7182	"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I"
XP_050586312.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis"
XP_050600756.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050582316.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050597201.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050576642.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050595227.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050575860.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_050585694.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050594841.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_050595092.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050577811.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050575696.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598461.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050589281.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050587286.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050587158.1	4	Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261	"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_050576151.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050582857.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050595471.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination"
XP_050595034.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050590736.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050582443.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050573843.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050592405.1	9	MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263	"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis"
XP_050582714.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050596207.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050600963.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5912;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6	"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050597963.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050596003.1	17	MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_050579073.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050588567.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050574558.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050590123.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050573851.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_050579782.1	18	Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane"
XP_050598889.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_050575219.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050585365.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050581340.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050589385.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050574652.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050582492.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_050581997.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050582475.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050597592.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050589884.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_050593493.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050579135.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050586850.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050579803.1	18	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_050575484.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_050582818.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050587852.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_050582471.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050574542.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050600697.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050580708.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050589311.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050599983.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-1989781	"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression"
XP_050581491.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050587838.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050598111.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050576424.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050597360.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050597447.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050599294.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050592520.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_050589923.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050598229.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050582141.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050588059.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy"
XP_050573673.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719	"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ion homeostasis";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors"
XP_050582259.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775	"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Ion homeostasis"
XP_050575801.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_050594965.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_050579210.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050574011.1	179	Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-162588;Reactome: R-HSA-2559585;Reactome: R-HSA-5675482;Reactome: R-HSA-9010553;Reactome: R-HSA-2672351;Reactome: R-HSA-8876493;Reactome: R-HSA-2467813;Reactome: R-HSA-901032;Reactome: R-HSA-156827;Reactome: R-HSA-68827;Reactome: R-HSA-156902;Reactome: R-HSA-5687128;Reactome: R-HSA-201681;Reactome: R-HSA-110320;Reactome: R-HSA-2559580;Reactome: R-HSA-9033241;Reactome: R-HSA-4608870;Reactome: R-HSA-9636383;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-975110;Reactome: R-HSA-5205685;Reactome: R-HSA-8866654;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-182971;Reactome: R-HSA-450408;Reactome: R-HSA-72689;Reactome: R-HSA-5696395;Reactome: R-HSA-9637628;Reactome: R-HSA-1169091;Reactome: R-HSA-4641263;Reactome: R-HSA-349425;Reactome: R-HSA-937041;Reactome: R-HSA-5689877;Reactome: R-HSA-382556;Reactome: R-HSA-1295596;Reactome: R-HSA-2173788;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-6804757;Reactome: R-HSA-975957;Reactome: R-HSA-445989;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-2979096;Reactome: R-HSA-5358346;Reactome: R-HSA-72764;Reactome: R-HSA-8854050;Reactome: R-HSA-1236382;Reactome: R-HSA-205043;Reactome: R-HSA-9633012;Reactome: R-HSA-983168;Reactome: R-HSA-3322077;Reactome: R-HSA-174048;Reactome: R-HSA-5357905;Reactome: R-HSA-2894862;Reactome: R-HSA-1799339;Reactome: R-HSA-9615710;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-977225;Reactome: R-HSA-5357956;Reactome: R-HSA-5655862;Reactome: R-HSA-9013973;Reactome: R-HSA-975956;Reactome: R-HSA-2173791;Reactome: R-HSA-912631;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-2408557;Reactome: R-HSA-8866652;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-400253;Reactome: R-HSA-69601;Reactome: R-HSA-532668;Reactome: R-HSA-174154;Reactome: R-HSA-6807004;Reactome: R-HSA-5675221;Reactome: R-HSA-2173796;Reactome: R-HSA-8939236;Reactome: R-HSA-975163;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-9646399;Reactome: R-HSA-5362768;Reactome: R-HSA-6791226;Reactome: R-HSA-9604323;Reactome: R-HSA-8856828;Reactome: R-HSA-936440;Reactome: R-HSA-8948747;Reactome: R-HSA-937042;Reactome: R-HSA-5610783;Reactome: R-HSA-5656169;Reactome: R-HSA-1169408;Reactome: R-HSA-174113;Reactome: R-HSA-110312;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-975144;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-69231;Reactome: R-HSA-6782210;Reactome: R-HSA-3785653;Reactome: R-HSA-110314;Reactome: R-HSA-1358803;Reactome: R-HSA-174184;Reactome: R-HSA-5654727;Reactome: R-HSA-5656121;Reactome: R-HSA-2122948;Reactome: R-HSA-6804756;Reactome: R-HSA-937039;Reactome: R-HSA-5693565;Reactome: R-HSA-8941858;Reactome: R-HSA-9014325;Reactome: R-HSA-192823;Reactome: R-HSA-202424;Reactome: R-HSA-5696397;Reactome: R-HSA-2173795;Reactome: R-HSA-69017;Reactome: R-HSA-168638;Reactome: R-HSA-5676590;Reactome: R-HSA-9613829;Reactome: R-HSA-2565942;Reactome: R-HSA-5693607;Reactome: R-HSA-3134975;Reactome: R-HSA-5654733;Reactome: R-HSA-6782135;Reactome: R-HSA-209560;Reactome: R-HSA-1253288;Reactome: R-HSA-2644606;Reactome: R-HSA-6804760;Reactome: R-HSA-5685942;Reactome: R-HSA-5654732;Reactome: R-HSA-2691232;Reactome: R-HSA-936964;Reactome: R-HSA-9645460;Reactome: R-HSA-8875360;Reactome: R-HSA-5607761;Reactome: R-HSA-2559582;Reactome: R-HSA-174490;Reactome: R-HSA-72706;Reactome: R-HSA-180585;Reactome: R-HSA-179409;Reactome: R-HSA-5654726;Reactome: R-HSA-3769402;Reactome: R-HSA-5684264;Reactome: R-HSA-9013507;Reactome: R-HSA-4641258;Reactome: R-HSA-175474;Reactome: R-HSA-69541;Reactome: R-HSA-5689896;Reactome: R-HSA-5678895;Reactome: R-HSA-209543;Reactome: R-HSA-5610785;Reactome: R-HSA-168927;Reactome: R-HSA-8863795;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-937072;Reactome: R-HSA-168928;Reactome: R-HSA-8849469;Reactome: R-HSA-450302;Reactome: R-HSA-5689901;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-6783310	"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Budding and maturation of HIV virion";"Oncogene Induced Senescence";"Regulation of necroptotic cell death";"Regulation of expression of SLITs and ROBOs";"Stimuli-sensing channels";"InlA-mediated entry of Listeria monocytogenes into host cells";"Separation of Sister Chromatids";"ER Quality Control Compartment (ERQC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"CDT1 association with the CDC6:ORC:origin complex";"Peptide chain elongation";"MAPK6/MAPK4 signaling";"TCF dependent signaling in response to WNT";"Translesion Synthesis by POLH";"Oxidative Stress Induced Senescence";"Peroxisomal protein import";"Asymmetric localization of PCP proteins";"Prevention of phagosomal-lysosomal fusion";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Pink/Parkin Mediated Mitophagy";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"EGFR downregulation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Formation of a pool of free 40S subunits";"Formation of Incision Complex in GG-NER";"Modulation by Mtb of host immune system";"Activation of NF-kappaB in B cells";"Regulation of FZD by ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"IKK complex recruitment mediated by RIP1";"Josephin domain DUBs";"ABC-family proteins mediated transport";"Spry regulation of FGF signaling";"Downregulation of TGF-beta receptor signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Regulation of TP53 Degradation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Hedgehog ligand biogenesis";"Eukaryotic Translation Termination";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"NRIF signals cell death from the nucleus";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Antigen processing: Ubiquitination & Proteasome degradation";"Glycogen synthesis";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of TNFR1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SRP-dependent cotranslational protein targeting to membrane";"Late endosomal microautophagy";"CLEC7A (Dectin-1) signaling";"Neddylation";"Iron uptake and transport";"Amyloid fiber formation";"TNFR1-induced NFkappaB signaling pathway";"Translesion synthesis by POLK";"TICAM1-dependent activation of IRF3/IRF7";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of signaling by CBL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Selenocysteine synthesis";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Circadian Clock";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of MET activity";"Negative regulation of MAPK pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Aggrephagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulation of NOTCH4 signaling";"Clathrin-mediated endocytosis";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of PTEN localization";"IRAK2 mediated activation of TAK1 complex";"Degradation of GLI2 by the proteasome";"Termination of translesion DNA synthesis";"ISG15 antiviral mechanism";"SCF-beta-TrCP mediated degradation of Emi1";"Translesion synthesis by REV1";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"ER-Phagosome pathway";"G2/M Checkpoints";"Cyclin D associated events in G1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Myoclonic epilepsy of Lafora";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of ERBB2:ERBB3 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of FGFR2 signaling";"Translesion synthesis by POLI";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of TP53 Activity through Phosphorylation";"IRAK1 recruits IKK complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of RUNX3 expression and activity";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Viral mRNA Translation";"Downstream TCR signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"CDK-mediated phosphorylation and removal of Cdc6";"NOD1/2 Signaling Pathway";"NIK-->noncanonical NF-kB signaling";"Chaperone Mediated Autophagy";"Regulation of PLK1 Activity at G2/M Transition";"Processing of DNA double-strand break ends";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of FGFR4 signaling";"Dual incision in TC-NER";"NF-kB is activated and signals survival";"Downregulation of ERBB4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of TP53 Activity through Methylation";"HDR through Homologous Recombination (HRR)";"Negative regulation of FGFR3 signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Alpha-protein kinase 1 signaling pathway";"InlB-mediated entry of Listeria monocytogenes into host cell";"Dectin-1 mediated noncanonical NF-kB signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Membrane binding and targetting of GAG proteins";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Vif-mediated degradation of APOBEC3G";"APC-Cdc20 mediated degradation of Nek2A";"Negative regulation of FGFR1 signaling";"Deactivation of the beta-catenin transactivating complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of DVL";"Assembly Of The HIV Virion";"Stabilization of p53";"Ovarian tumor domain proteases";"Defective CFTR causes cystic fibrosis";"p75NTR recruits signalling complexes";"GLI3 is processed to GLI3R by the proteasome";"TICAM1, RIP1-mediated IKK complex recruitment";"Downregulation of ERBB2 signaling";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"activated TAK1 mediates p38 MAPK activation";"Metalloprotease DUBs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Fanconi Anemia Pathway"
XP_050576063.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050593243.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050589656.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_050591383.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050598021.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050582895.1	11	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-2559580;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302	"Thermogenesis";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"p38MAPK events";"Oxidative Stress Induced Senescence";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation"
XP_050574358.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050581144.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050592773.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_050591702.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050579906.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050599305.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050577217.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050573813.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050589274.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050579223.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050598025.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050586748.1	14	Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-2500257;Reactome: R-HSA-2565942;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-141444;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Regulation of PLK1 Activity at G2/M Transition";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050575233.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050588146.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050577692.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8939243	"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050586788.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050573881.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050582458.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050597666.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_050575352.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050599564.1	8	MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-241	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_050594774.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050589423.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050573593.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050588023.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy"
XP_050592748.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050573989.1	10	MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527	"D-galactose detoxification";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Stachyose degradation"
XP_050588819.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507	"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_050598965.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050600947.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050596062.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050596176.1	14	MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-8055	"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_050585411.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050577158.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050598485.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_050595360.1	7	MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_050597428.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050576378.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050584094.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050583777.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050592193.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_050585926.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050580973.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050598860.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_050583851.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050592949.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050585337.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050597451.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050594414.1	12	Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane"
XP_050575453.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050585287.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050599990.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050599296.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050574114.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050590810.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050575736.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050580169.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_050587257.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_050597941.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050590997.1	7	Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-4086400	"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"Degradation of DVL";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"PCP/CE pathway"
XP_050589880.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_050574332.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050582369.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050596170.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-432142	"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL"
XP_050598500.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050580825.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050596347.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_050573670.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001	"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade"
XP_050594679.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050593048.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_050600466.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050578043.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050597598.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050580648.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050591623.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050581002.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_050575685.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050582490.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_050580042.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_050574588.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050587927.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050581781.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050574493.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351	"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_050596884.1	24	Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"Ca2+ pathway";"G-protein activation";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events"
XP_050592432.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050584599.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050583149.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050578691.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001	"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_050587917.1	17	MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-163765	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Pyruvate metabolism";"ChREBP activates metabolic gene expression"
XP_050590636.1	10	KEGG: 00650+2.3.3.10;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174	"Butanoate metabolism";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)"
XP_050581572.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050574554.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050581734.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_050587318.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_050599322.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050585550.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050578124.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050592934.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050597434.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050584062.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050593971.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex"
XP_050585563.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050584063.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050590596.1	29	Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-3371511;Reactome: R-HSA-912446;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453	"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"HSF1 activation";"Meiotic recombination";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response"
XP_050585042.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050594418.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_050598335.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050588039.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050598530.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050581301.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050592662.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_050587948.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_050589565.1	4	KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050589521.1	22	Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5673000	"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"RAF activation"
XP_050600558.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050574053.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050581118.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050593587.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-109704	"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade"
XP_050578086.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"G2/M DNA damage checkpoint"
XP_050574244.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_050580134.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050595099.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050591989.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050591146.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050590151.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_050579777.1	18	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050587680.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid"
XP_050581200.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4	"Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_050578401.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050586827.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050574325.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050595336.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050584496.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050585431.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-983231	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production"
XP_050592150.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050575568.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050588054.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436	"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050587304.1	6	Reactome: R-HSA-983168;Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8939902	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Regulation of RUNX2 expression and activity"
XP_050575310.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050581335.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205	"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose"
XP_050575342.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050581331.1	7	Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8	"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism"
XP_050590605.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050575518.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050599547.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897	"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes"
XP_050592477.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins";"MHC class II antigen presentation"
XP_050577825.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050576446.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_050590774.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050577837.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050587266.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_050579232.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_050600706.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050584675.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050596890.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050582819.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050588097.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-5617472;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050583355.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050580710.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050595531.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337	"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding"
XP_050594040.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050584938.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_050594491.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_050578958.1	6	KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_050585436.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050580731.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050583943.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050581603.1	10	MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Folate transformations II (plants)";"One carbon pool by folate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)"
XP_050587416.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_050574262.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_050592991.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_050591983.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050579910.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050579294.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050597226.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050574095.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050575264.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050597593.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050599324.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_050597860.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050578408.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050573090.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050598094.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050598481.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050579171.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050600350.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050579792.1	18	Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050594707.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050587139.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_050581999.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050573703.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"Neddylation";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050589165.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050575376.1	13	Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427	"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"LDL clearance";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation"
XP_050591208.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050595350.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis"
XP_050584670.1	6	Reactome: R-HSA-5609978;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"Defective GALT can cause Galactosemia";"Galactose catabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_050576658.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050586943.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050595148.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050581281.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050598284.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050580014.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050582074.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050578301.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050580210.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_050574041.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050589394.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_050594210.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050581117.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_050580489.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050600267.1	10	Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-7328	"Galactose catabolism";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_050592030.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050589479.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050583353.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050589063.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050574822.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_050578162.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050584181.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_050597768.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050575347.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050596525.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050574500.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050573748.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490	"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen degradation"
XP_050587928.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050589707.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_050581271.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050573810.1	15	MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221	"Glycerol degradation to butanol";"Glycolysis";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_050586925.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050579283.1	17	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane"
XP_050593549.1	9	Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_050590966.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050580938.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050574625.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050593646.1	13	MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5	"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism"
XP_050586773.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling"
XP_050581272.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050590617.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050574299.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050597111.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050595659.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050590660.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050596891.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050591913.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050586021.1	4	Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-72163	"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway"
XP_050588148.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050581549.1	20	Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604	"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"HSF1-dependent transactivation";"Macroautophagy";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Regulation of PTEN gene transcription";"Thermogenesis";"Amino acids regulate mTORC1";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"PI3K-Akt signaling pathway";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"PIP3 activates AKT signaling"
XP_050579069.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050576191.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050593065.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050598590.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050574526.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3	"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism"
XP_050586836.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050592812.1	5	Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_050580484.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050597344.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050574756.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590	"Blockage of phagosome acidification";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation"
XP_050576016.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050592266.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050599331.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050583797.1	8	MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate metabolism"
XP_050598731.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050587243.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis";"Ion channel transport"
XP_050587914.1	17	MetaCyc: PWY-6679;MetaCyc: PWY-5744;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2	"Jadomycin biosynthesis";"Glyoxylate assimilation";"Carnitine metabolism";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism"
XP_050575665.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination"
XP_050598207.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050593165.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050598327.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_050586201.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050585495.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050600748.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050589926.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050587265.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_050573652.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-3371571	"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"HSF1-dependent transactivation"
XP_050589473.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050595637.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050573974.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050582694.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_050589058.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719	"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors"
XP_050577790.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7589	"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Synthesis of PA";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_050593117.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050590437.1	11	MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6607;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-5381;MetaCyc: PWY-6596;MetaCyc: PWY-7185;MetaCyc: PWY-6606	"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyridine nucleotide cycling (plants)";"Adenosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II"
XP_050597427.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050588176.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050593742.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050583908.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-983168	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050578080.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050575302.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_050595861.1	19	Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-381426	"Scavenging by Class B Receptors";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"VLDL clearance";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Scavenging by Class A Receptors";"LDL remodeling";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"LDL clearance";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050573605.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_050574539.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050596145.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-211945	"Xenobiotics";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"PPARA activates gene expression";"Phase I - Functionalization of compounds"
XP_050595053.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050596867.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050588500.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050597336.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_050591943.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_050580440.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050592928.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050578493.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050598517.1	14	KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-7409	"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_050574752.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_050589669.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-1433559	"Neddylation";"Regulation of KIT signaling"
XP_050584932.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_050588995.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050581610.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050596066.1	16	Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1250342;Reactome: R-HSA-1963640;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196	"Nuclear signaling by ERBB4";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB4 signaling";"GRB2 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling"
XP_050600747.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050576530.1	3	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_050576570.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050581230.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050573908.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050593718.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050588389.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050584129.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050597366.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_050573628.1	4	MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis"
XP_050591834.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68616	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_050580026.1	60	MetaCyc: PWY-7094;Reactome: R-HSA-77305;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7606;KEGG: 00362+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-5138;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7778;KEGG: 00280+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00380+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-5789;Reactome: R-HSA-77350;KEGG: 00640+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00903+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-6946;Reactome: R-HSA-77285;KEGG: 00650+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-5136;Reactome: R-HSA-77346;MetaCyc: PWY-7656;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00720+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-6944;KEGG: 00410+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;Reactome: R-HSA-77348;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;Reactome: R-HSA-1482798	"Fatty acid salvage";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Tryptophan metabolism";"Benzoyl-coa degradation I (aerobic)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Benzoate degradation";"Geraniol degradation";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid degradation";"2-methylpropene degradation";"Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"Tryptophan metabolism";"Benzoate degradation";"Phenylalanine metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Propanoate metabolism";"Fatty acid elongation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Aminobenzoate degradation";"Pyruvate fermentation to hexanol (engineered)";"Caprolactam degradation";"Methyl tert-butyl ether degradation";"Limonene and pinene degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid elongation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Butanoate metabolism";"Butanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"Fermentation to 2-methylbutanoate";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Spodoptera littoralis pheromone biosynthesis";"Lysine degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Carbon fixation pathways in prokaryotes";"4-hydroxybenzoate biosynthesis III (plants)";"Androstenedione degradation";"beta-Alanine metabolism";"Caprolactam degradation";"Pyruvate fermentation to butanol I";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Acyl chain remodeling of CL"
XP_050573873.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_050592188.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050590541.1	9	Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Neddylation"
XP_050575450.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_050597224.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050588729.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050586845.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050595015.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050594942.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050574034.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050576795.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050582787.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050586939.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050589413.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050595777.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_050575469.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050598775.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587	"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)"
XP_050577305.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050587278.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050593177.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-180910	"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"Vpr-mediated nuclear import of PICs"
XP_050573875.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_050597925.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050600000.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050586475.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050594411.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition"
XP_050595981.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050591436.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050587840.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050581972.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050577258.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050587485.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050581033.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050598102.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050580414.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_050599337.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050579291.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050580344.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-383280;Reactome: R-HSA-212436	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway"
XP_050586388.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1474228;Reactome: R-HSA-1592389	"Collagen degradation";"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases"
XP_050593904.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050596996.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050599617.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050584518.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050599034.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_050589057.1	12	Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-451308;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;MetaCyc: PWY-7221	"NrCAM interactions";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis"
XP_050586678.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"T cell receptor signaling pathway";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050585908.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050588877.1	42	MetaCyc: PWY-6435;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-6583;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-6883;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7656;KEGG: 00640+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-6863;MetaCyc: PWY-7779;KEGG: 00903+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7606;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7778;MetaCyc: PWY-5138;MetaCyc: PWY-5177;MetaCyc: PWY-7401;KEGG: 00360+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789	"4-hydroxybenzoate biosynthesis III (plants)";"Caprolactam degradation";"beta-Alanine metabolism";"Androstenedione degradation";"Pyruvate fermentation to butanol I";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"Fermentation to 2-methylbutanoate";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Spodoptera littoralis pheromone biosynthesis";"Propanoate metabolism";"Fatty acid elongation";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Pyruvate fermentation to hexanol (engineered)";"Methyl tert-butyl ether degradation";"Limonene and pinene degradation";"Butanoate metabolism";"Fatty acid salvage";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Tryptophan metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"2-methylpropene degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Phenylalanine metabolism";"Benzoate degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_050599306.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050574628.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050585851.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050595070.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050581628.1	8	MetaCyc: PWY-7193;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_050600895.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418597	"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (z) signalling events"
XP_050588935.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen degradation";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures"
XP_050598489.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050580890.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_050584024.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050598968.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050581954.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050598519.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053	"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II"
XP_050585203.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050588325.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane"
XP_050593439.1	7	MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686	"UMP biosynthesis II";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis I"
XP_050584232.1	42	Reactome: R-HSA-5617472;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-1221632;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-110331;Reactome: R-HSA-8936459;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-2559586;Reactome: R-HSA-5578749;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-2559582;Reactome: R-HSA-5334118;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-201722	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"Meiotic synapsis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation by small RNAs";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HCMV Early Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"DNA methylation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"HDMs demethylate histones";"Formation of the beta-catenin:TCF transactivating complex"
XP_050582476.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050591648.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050592723.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050573949.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050583982.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050581332.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205	"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose"
XP_050585576.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050598259.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050580892.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050592091.1	8	KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050594351.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050596352.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050584507.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050600933.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs"
XP_050574772.1	11	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571	"Thermogenesis";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)"
XP_050599965.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050595456.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050598761.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_050584915.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050593434.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050579033.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050585363.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_050593719.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050580285.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050598504.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050599977.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050589950.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_050591769.1	52	Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-73780;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167290;Reactome: R-HSA-749476;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-73980;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-72203;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-76061	"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"FGFR2 alternative splicing";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Chain Elongation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Pausing and recovery of HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050590739.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_050599612.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050598473.1	12	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"G alpha (q) signalling events";"Rho GTPase cycle";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050597483.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050590152.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050585914.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050592443.1	182	Reactome: R-HSA-5687128;Reactome: R-HSA-201681;Reactome: R-HSA-110320;Reactome: R-HSA-2559580;Reactome: R-HSA-2467813;Reactome: R-HSA-901032;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-68827;Reactome: R-HSA-2559585;Reactome: R-HSA-5675482;Reactome: R-HSA-9010553;Reactome: R-HSA-8876493;Reactome: R-HSA-2672351;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-72649;Reactome: R-HSA-174178;Reactome: R-HSA-162588;Reactome: R-HSA-5689877;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-2173788;Reactome: R-HSA-1295596;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-6804757;Reactome: R-HSA-975957;Reactome: R-HSA-9637628;Reactome: R-HSA-1169091;Reactome: R-HSA-4641263;Reactome: R-HSA-349425;Reactome: R-HSA-937041;Reactome: R-HSA-975110;Reactome: R-HSA-5205685;Reactome: R-HSA-8866654;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-182971;Reactome: R-HSA-450408;Reactome: R-HSA-5696395;Reactome: R-HSA-72689;Reactome: R-HSA-9033241;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-9636383;Reactome: R-HSA-5668541;Reactome: R-HSA-9615710;Reactome: R-HSA-2894862;Reactome: R-HSA-1799339;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-205043;Reactome: R-HSA-9633012;Reactome: R-HSA-983168;Reactome: R-HSA-3322077;Reactome: R-HSA-174048;Reactome: R-HSA-5357905;Reactome: R-HSA-8854050;Reactome: R-HSA-1236382;Reactome: R-HSA-445989;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-2979096;Reactome: R-HSA-5358346;Reactome: R-HSA-72764;Reactome: R-HSA-2173796;Reactome: R-HSA-5675221;Reactome: R-HSA-8939236;Reactome: R-HSA-975163;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-9646399;Reactome: R-HSA-5362768;Reactome: R-HSA-2408557;Reactome: R-HSA-8866652;Reactome: R-HSA-211733;Reactome: R-HSA-400253;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-532668;Reactome: R-HSA-174154;Reactome: R-HSA-6807004;Reactome: R-HSA-5655862;Reactome: R-HSA-5357956;Reactome: R-HSA-975956;Reactome: R-HSA-9013973;Reactome: R-HSA-2173791;Reactome: R-HSA-912631;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-977225;Reactome: R-HSA-1358803;Reactome: R-HSA-174184;Reactome: R-HSA-5654727;Reactome: R-HSA-174113;Reactome: R-HSA-110312;Reactome: R-HSA-975144;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-69231;Reactome: R-HSA-6782210;Reactome: R-HSA-3785653;Reactome: R-HSA-110314;Reactome: R-HSA-936440;Reactome: R-HSA-8948747;Reactome: R-HSA-937042;Reactome: R-HSA-5610783;Reactome: R-HSA-5656169;Reactome: R-HSA-1169408;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-8856828;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-72702;Reactome: R-HSA-9613829;Reactome: R-HSA-5696397;Reactome: R-HSA-2173795;Reactome: R-HSA-69017;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-192823;Reactome: R-HSA-202424;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-2122948;Reactome: R-HSA-5693565;Reactome: R-HSA-937039;Reactome: R-HSA-8941858;Reactome: R-HSA-179409;Reactome: R-HSA-5654726;Reactome: R-HSA-3769402;Reactome: R-HSA-5684264;Reactome: R-HSA-9645460;Reactome: R-HSA-8875360;Reactome: R-HSA-174490;Reactome: R-HSA-5607761;Reactome: R-HSA-2559582;Reactome: R-HSA-180585;Reactome: R-HSA-72706;Reactome: R-HSA-1253288;Reactome: R-HSA-209560;Reactome: R-HSA-6804760;Reactome: R-HSA-2644606;Reactome: R-HSA-5685942;Reactome: R-HSA-5654732;Reactome: R-HSA-936964;Reactome: R-HSA-2691232;Reactome: R-HSA-5693607;Reactome: R-HSA-2565942;Reactome: R-HSA-3134975;Reactome: R-HSA-5654733;Reactome: R-HSA-6782135;Reactome: R-HSA-937072;Reactome: R-HSA-168928;Reactome: R-HSA-450302;Reactome: R-HSA-8849469;Reactome: R-HSA-5689901;Reactome: R-HSA-75815;Reactome: R-HSA-6783310;Reactome: R-HSA-5632684;Reactome: R-HSA-8863795;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-5689896;Reactome: R-HSA-5678895;Reactome: R-HSA-209543;Reactome: R-HSA-5610785;Reactome: R-HSA-168927;Reactome: R-HSA-9013507;Reactome: R-HSA-4641258;Reactome: R-HSA-175474;Reactome: R-HSA-69541	"MAPK6/MAPK4 signaling";"TCF dependent signaling in response to WNT";"Translesion Synthesis by POLH";"Oxidative Stress Induced Senescence";"Separation of Sister Chromatids";"ER Quality Control Compartment (ERQC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"CDT1 association with the CDC6:ORC:origin complex";"Oncogene Induced Senescence";"Regulation of necroptotic cell death";"Regulation of expression of SLITs and ROBOs";"InlA-mediated entry of Listeria monocytogenes into host cells";"Stimuli-sensing channels";"UCH proteinases";"Degradation of AXIN";"Translation initiation complex formation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Budding and maturation of HIV virion";"Josephin domain DUBs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downregulation of TGF-beta receptor signaling";"Spry regulation of FGF signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Regulation of TP53 Degradation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Modulation by Mtb of host immune system";"Activation of NF-kappaB in B cells";"Regulation of FZD by ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"IKK complex recruitment mediated by RIP1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Pink/Parkin Mediated Mitophagy";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"EGFR downregulation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Formation of Incision Complex in GG-NER";"Formation of a pool of free 40S subunits";"Peroxisomal protein import";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Prevention of phagosomal-lysosomal fusion";"TNFR2 non-canonical NF-kB pathway";"Late endosomal microautophagy";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SRP-dependent cotranslational protein targeting to membrane";"CLEC7A (Dectin-1) signaling";"Neddylation";"NRIF signals cell death from the nucleus";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Antigen processing: Ubiquitination & Proteasome degradation";"Glycogen synthesis";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of TNFR1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Hedgehog ligand biogenesis";"Eukaryotic Translation Termination";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Negative regulation of MAPK pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Aggrephagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Selenocysteine synthesis";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Circadian Clock";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of MET activity";"Translesion synthesis by POLK";"TNFR1-induced NFkappaB signaling pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TICAM1-dependent activation of IRF3/IRF7";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of signaling by CBL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Iron uptake and transport";"Amyloid fiber formation";"Downregulation of ERBB2:ERBB3 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of FGFR2 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Translesion synthesis by REV1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"ER-Phagosome pathway";"G2/M Checkpoints";"Cyclin D associated events in G1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Myoclonic epilepsy of Lafora";"Recognition of DNA damage by PCNA-containing replication complex";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of PTEN localization";"IRAK2 mediated activation of TAK1 complex";"Degradation of GLI2 by the proteasome";"Termination of translesion DNA synthesis";"ISG15 antiviral mechanism";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Clathrin-mediated endocytosis";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Ribosomal scanning and start codon recognition";"Chaperone Mediated Autophagy";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"CDK-mediated phosphorylation and removal of Cdc6";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Viral mRNA Translation";"Downstream TCR signaling";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"IRAK1 recruits IKK complex";"Regulation of RUNX3 expression and activity";"APC-Cdc20 mediated degradation of Nek2A";"Negative regulation of FGFR1 signaling";"Deactivation of the beta-catenin transactivating complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Alpha-protein kinase 1 signaling pathway";"InlB-mediated entry of Listeria monocytogenes into host cell";"Membrane binding and targetting of GAG proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Vif-mediated degradation of APOBEC3G";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Downregulation of ERBB4 signaling";"NF-kB is activated and signals survival";"Regulation of TP53 Activity through Methylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDR through Homologous Recombination (HRR)";"Negative regulation of FGFR3 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Processing of DNA double-strand break ends";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of FGFR4 signaling";"Dual incision in TC-NER";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"activated TAK1 mediates p38 MAPK activation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Metalloprotease DUBs";"Ubiquitin-dependent degradation of Cyclin D";"Fanconi Anemia Pathway";"Hedgehog 'on' state";"Downregulation of ERBB2 signaling";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Ovarian tumor domain proteases";"Defective CFTR causes cystic fibrosis";"p75NTR recruits signalling complexes";"GLI3 is processed to GLI3R by the proteasome";"TICAM1, RIP1-mediated IKK complex recruitment";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of DVL";"Assembly Of The HIV Virion";"Stabilization of p53"
XP_050598008.1	7	KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00030+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Gluconeogenesis"
XP_050581203.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050582899.1	11	Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-2559580	"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"p38MAPK events";"Oxidative Stress Induced Senescence"
XP_050574842.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050576509.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050582036.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050596524.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050582089.1	7	Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166	"Role of phospholipids in phagocytosis";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PA"
XP_050594042.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050591254.1	3	KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_050595809.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050582790.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050593246.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050592473.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050582467.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050585329.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050576911.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050581254.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_050585016.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_050586171.1	7	KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis"
XP_050588909.1	3	MetaCyc: PWY-7158;MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96	"L-phenylalanine degradation V";"Tetrahydropteridine recycling";"Folate biosynthesis"
XP_050582249.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation"
XP_050592881.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050574357.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050595446.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050576957.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050579684.1	25	Reactome: R-HSA-8936459;Reactome: R-HSA-8941284;Reactome: R-HSA-8941332;Reactome: R-HSA-8939236;Reactome: R-HSA-8939243;Reactome: R-HSA-8939245;Reactome: R-HSA-9616222;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247;Reactome: R-HSA-8931987;Reactome: R-HSA-8939242;Reactome: R-HSA-8941326;Reactome: R-HSA-8935964;Reactome: R-HSA-9018519;Reactome: R-HSA-8878166;Reactome: R-HSA-8951911;Reactome: R-HSA-8939902;Reactome: R-HSA-8951936;Reactome: R-HSA-8941858;Reactome: R-HSA-8939256;Reactome: R-HSA-8941333;Reactome: R-HSA-8939246;Reactome: R-HSA-8940973;Reactome: R-HSA-8877330;Reactome: R-HSA-8934593	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in BCR signaling";"Transcriptional regulation of granulopoiesis";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates bone development";"RUNX1 regulates expression of components of tight junctions";"Estrogen-dependent gene expression";"Transcriptional regulation by RUNX2";"RUNX3 regulates RUNX1-mediated transcription";"Regulation of RUNX2 expression and activity";"RUNX3 regulates p14-ARF";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates osteoblast differentiation";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX1 Expression and Activity"
XP_050583616.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050578794.1	3	MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_050578041.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_050594332.1	10	MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587;Reactome: R-HSA-1483166	"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA"
XP_050594781.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050585853.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050592435.1	4	KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603	"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine"
XP_050575514.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050587407.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050582595.1	30	Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-2564830;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-167158	"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex"
XP_050599987.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050599319.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050585598.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787	"Adenylate cyclase inhibitory pathway";"PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state"
XP_050590337.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_050580911.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050577757.1	18	MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_050600882.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050584201.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050582627.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050594416.1	9	Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-69205	"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription"
XP_050593630.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050592397.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_050597983.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050573493.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050586015.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-72203	"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050580777.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050575691.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050574501.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050592065.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050580225.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050577537.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050578782.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050600481.1	8	Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111464	"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_050582213.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_050575803.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_050574376.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050596950.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050580898.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050588835.1	6	KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050588085.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_050595462.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050574821.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_050598332.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050585493.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_050599312.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050588572.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050580620.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050581142.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167238	"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050578129.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050594616.1	14	Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050583993.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050584576.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050590718.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050588856.1	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_050577103.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_050574492.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050576643.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050583975.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_050599260.1	26	Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050586868.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050575771.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050596040.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_050597042.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050578156.1	7	Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_050579031.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050577563.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050575681.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050599871.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050575694.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050587420.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_050586954.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050600598.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_050573918.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050575909.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050590490.1	11	Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-193692	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR"
XP_050589774.1	7	Reactome: R-HSA-9022692;KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;MetaCyc: PWY-6074;MetaCyc: PWY-2541;Reactome: R-HSA-191273;MetaCyc: PWY-7154	"Regulation of MECP2 expression and activity";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Zymosterol biosynthesis";"Phytosterol biosynthesis (plants)";"Cholesterol biosynthesis";"Ergosterol biosynthesis II"
XP_050599417.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050598182.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050574644.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_050588528.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_050584971.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation"
XP_050590867.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050579383.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050600521.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_050592993.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_050573654.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050574951.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050589686.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050579360.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050600786.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050590811.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050590556.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050575908.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050576243.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050590830.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050588814.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050589117.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050585478.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050574928.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050596925.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_050590325.1	34	Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-9639288;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-4085377	"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amino acids regulate mTORC1";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins"
XP_050574952.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050592076.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050583588.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050582391.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050593192.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_050586236.1	13	MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101	"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation"
XP_050600266.1	10	MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2	"D-galactose detoxification";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"Galactose metabolism"
XP_050594213.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050588608.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050589307.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050589143.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050574546.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050596895.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_050588131.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050596993.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_050589283.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050583875.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050588575.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050597141.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_050592481.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050577241.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050597296.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050576021.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_050591824.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050579805.1	18	Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050596808.1	6	Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118	"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle"
XP_050582624.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050581495.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050587263.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_050587142.1	9	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-112043	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events"
XP_050576195.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050592155.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_050576679.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_050594154.1	4	KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050579668.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562	"Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria"
XP_050598698.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050573027.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_050586261.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050593563.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135	"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation";"MAP2K and MAPK activation"
XP_050577665.1	12	Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381070;Reactome: R-HSA-6798695;Reactome: R-HSA-381183;KEGG: 00860+4.2.1.24;Reactome: R-HSA-983170;MetaCyc: PWY-5188;Reactome: R-HSA-3371453;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"IRE1alpha activates chaperones";"Neutrophil degranulation";"ATF6 (ATF6-alpha) activates chaperone genes";"Porphyrin and chlorophyll metabolism";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Tetrapyrrole biosynthesis I (from glutamate)";"Regulation of HSF1-mediated heat shock response";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_050595770.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050597606.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050598756.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050594777.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050595889.1	18	Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243	"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery"
XP_050588625.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050590177.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_050586096.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_050591700.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050589003.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_050593604.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050592034.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050578753.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050595319.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050576952.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050574347.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050584276.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050600705.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050595096.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050587941.1	14	Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-193692	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Regulated proteolysis of p75NTR"
XP_050579483.1	20	Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121	"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI"
XP_050592647.1	13	MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;Reactome: R-HSA-2029485;Reactome: R-HSA-2871796;Reactome: R-HSA-202433;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871809	"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"Role of phospholipids in phagocytosis";"FCERI mediated MAPK activation";"Generation of second messenger molecules";"Phosphatidylinositol signaling system";"FCERI mediated Ca+2 mobilization"
XP_050594872.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050575664.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050599419.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050596386.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050574285.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050578215.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050577165.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade"
XP_050583045.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050597565.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-164378	"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling"
XP_050586219.1	2	Reactome: R-HSA-2173796;Reactome: R-HSA-6785807	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interleukin-4 and Interleukin-13 signaling"
XP_050580198.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_050595664.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050595389.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050597227.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-77595	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs"
XP_050584717.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_050599905.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050586143.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy"
XP_050596530.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050587643.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050577904.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_050578001.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_050593636.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050579713.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050588327.1	10	KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-1042;Reactome: R-HSA-70263	"Fructose and mannose metabolism";"Inositol phosphate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Gluconeogenesis"
XP_050580276.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_050587837.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050577417.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050573732.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050591428.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_050578804.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_050578889.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377	"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins"
XP_050579221.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050582974.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050573349.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050589823.1	7	MetaCyc: PWY-6363;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050581215.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050588073.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050596729.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050589156.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_050574259.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_050596230.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_050586847.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050584982.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050579021.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_050586119.1	6	MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122	"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis"
XP_050574513.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_050596535.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050589976.1	19	Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-983231;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-418885;Reactome: R-HSA-2029482;Reactome: R-HSA-8950505;Reactome: R-HSA-5663213;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-182971	"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"RHO GTPases Activate Formins";"Myogenesis";"Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"Factors involved in megakaryocyte development and platelet production";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"DCC mediated attractive signaling";"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"EGFR downregulation"
XP_050577553.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050590836.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050580078.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050593183.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379	"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events"
XP_050596928.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_050586374.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050586661.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050575206.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050581136.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050581697.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050581004.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_050585432.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482	"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050590913.1	10	Reactome: R-HSA-3000171;Reactome: R-HSA-975634;Reactome: R-HSA-977225;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902	"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Amyloid fiber formation";"Urate conversion to allantoin II";"Neutrophil degranulation";"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin III";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)"
XP_050578115.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_050584258.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050581278.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050589073.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050585423.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050595930.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050578742.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_050600027.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050598595.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050587971.1	3	KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669	"Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_050583330.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050578957.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation"
XP_050579387.1	29	Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-112382	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex"
XP_050578123.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050599259.1	26	Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082	"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression"
XP_050597501.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050577002.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-420029;Reactome: R-HSA-2173791	"Asymmetric localization of PCP proteins";"Tight junction interactions";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_050579132.1	7	MetaCyc: PWY-5514;MetaCyc: PWY-8004;MetaCyc: PWY-6855;Reactome: R-HSA-71336;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Pentose phosphate pathway";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_050596426.1	4	KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-917937;Reactome: R-HSA-189483	"Porphyrin and chlorophyll metabolism";"Heme degradation I";"Iron uptake and transport";"Heme degradation"
XP_050573022.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050598225.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"