Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_050489065.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_050491493.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling"
XP_050480097.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050476985.1	42	Reactome: R-HSA-2559580;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-8939236;Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-5334118;Reactome: R-HSA-110330;Reactome: R-HSA-5250924;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-110329;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-171306;Reactome: R-HSA-73772;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-212300;Reactome: R-HSA-73728;Reactome: R-HSA-606279;Reactome: R-HSA-5693565	"Oxidative Stress Induced Senescence";"HDACs deacetylate histones";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA methylation";"Recognition and association of DNA glycosylase with site containing an affected purine";"B-WICH complex positively regulates rRNA expression";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"RMTs methylate histone arginines";"Cleavage of the damaged pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Escape";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"PRC2 methylates histones and DNA";"RNA Polymerase I Promoter Opening";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050484301.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050485525.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050480509.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050496930.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050489499.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050485075.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050482507.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050493740.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_050472560.1	3	Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_050483904.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050475527.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050488175.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050485283.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050472130.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050477231.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"TP53 Regulates Metabolic Genes"
XP_050472171.1	3	KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_050473805.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050476041.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050473735.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050472339.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050473803.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050496917.1	3	Reactome: R-HSA-2173791;Reactome: R-HSA-4608870;Reactome: R-HSA-420029	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Asymmetric localization of PCP proteins";"Tight junction interactions"
XP_050483332.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation"
XP_050483088.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949	"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin"
XP_050488531.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517	"cGMP effects";"Ca2+ pathway";"Rap1 signalling"
XP_050491221.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_050491576.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050490986.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050493388.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050488658.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_050494522.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050495832.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050482156.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050482009.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050481991.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050482236.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050490298.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_050475476.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_050484669.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050482243.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050473398.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050496185.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050481816.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050478085.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis"
XP_050491538.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050492833.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050496434.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050481655.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050474325.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050493756.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050487645.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050487053.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_050486799.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway"
XP_050474177.1	3	Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741	"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050485734.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050471055.1	6	KEGG: 00710+5.1.3.1;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;Reactome: R-HSA-71336;MetaCyc: PWY-1861	"Carbon fixation in photosynthetic organisms";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Rubisco shunt";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050471964.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050469631.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050472205.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050469776.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050483651.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050487107.1	10	MetaCyc: PWY-5839;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5844;MetaCyc: PWY-5849;MetaCyc: PWY-5892;MetaCyc: PWY-5895;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5891;MetaCyc: PWY-7996	"Menaquinol-7 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-13 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I"
XP_050470969.1	5	KEGG: 00790+3.4.19.9;KEGG: 00513+2.4.1.142;MetaCyc: PWY-2161B;KEGG: 00510+2.4.1.142;Reactome: R-HSA-6798695	"Folate biosynthesis";"Various types of N-glycan biosynthesis";"Glutamate removal from folates";"N-Glycan biosynthesis";"Neutrophil degranulation"
XP_050485757.1	7	Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-7818	"Synthesis of PC";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_050479639.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050477486.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_050469760.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_050473417.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050485725.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050496513.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050472453.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050496199.1	5	MetaCyc: PWY-8043;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3	"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_050469702.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050480526.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_050473968.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050492292.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050472103.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050493226.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050475518.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050493516.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050481458.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_050477482.1	5	Reactome: R-HSA-4755579;MetaCyc: PWY-6129;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_050494377.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_050471696.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7559	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway"
XP_050487390.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_050473397.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050492730.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050469372.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050474539.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050473096.1	10	Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201	"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis"
XP_050482462.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050491688.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050473558.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions"
XP_050495779.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_050491178.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050474054.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050470600.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050472524.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_050484354.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050490913.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050484290.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050496926.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050491870.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050482557.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050474169.1	7	KEGG: 00360+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208	"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"Phenylketonuria";"Phenylalanine metabolism"
XP_050484018.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050479901.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050470418.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_050482473.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3"
XP_050482860.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781	"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)"
XP_050477472.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050476154.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_050497038.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493630.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050477255.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050485304.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050493721.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050481689.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050480106.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050485069.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050487331.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050475846.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_050476946.1	8	Reactome: R-HSA-1855183;KEGG: 00562+5.5.1.4;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-6664;MetaCyc: PWY-2301	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis"
XP_050485291.1	3	MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099	"L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling"
XP_050473388.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050469394.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050472490.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050492303.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050469568.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_050473736.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050475264.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050489897.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050476947.1	4	KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_050493109.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050470074.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050474416.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050481699.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050487844.1	11	Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_050474424.1	7	KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2	"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis"
XP_050474282.1	4	KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_050476162.1	5	KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68	"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_050493610.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050471528.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050477997.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050493208.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050477263.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_050490276.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050480322.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050492475.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050475141.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050483008.1	5	MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_050484305.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906	"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_050488946.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050484000.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Photosynthesis";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1"
XP_050478742.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050483619.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050487687.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050471615.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_050483850.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050494001.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050474730.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050486289.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050474432.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_050476308.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050478475.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050482521.1	19	Reactome: R-HSA-5626467;Reactome: R-HSA-5687128;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-3928662;Reactome: R-HSA-525793;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-182971	"RHO GTPases activate IQGAPs";"MAPK6/MAPK4 signaling";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"EPHB-mediated forward signaling";"Myogenesis";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"EGFR downregulation"
XP_050472049.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050470296.1	6	MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-6174;KEGG: 00900+2.7.1.36	"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_050472025.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050479594.1	8	Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-8953750	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Formation of apoptosome";"Transcriptional Regulation by E2F6"
XP_050473935.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050491787.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050474833.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050470699.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050484789.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050474498.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050479593.1	8	Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_050484155.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050482339.1	7	Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;MetaCyc: PWY-5695;Reactome: R-HSA-73817;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596	"Neutrophil degranulation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I"
XP_050493735.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050484906.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1362300	"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050486403.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism"
XP_050484004.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050474214.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_050470476.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050490740.1	19	Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-8856825	"VLDL assembly";"VLDL clearance";"Platelet sensitization by LDL";"LDL clearance";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class H Receptors";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Chylomicron assembly";"Chylomicron clearance";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis"
XP_050477778.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_050480355.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_050484150.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050476849.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050480041.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050496401.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050471613.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_050480313.1	3	KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050485685.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Aggrephagy"
XP_050481428.1	15	Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944	"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2"
XP_050470577.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050480714.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050477594.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9609736	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors"
XP_050470687.1	33	Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-141444	"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050475666.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050493628.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050487563.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_050490220.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050489936.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_050480237.1	10	MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050480329.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050478039.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050470824.1	8	Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER"
XP_050472609.1	6	MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_050470187.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050487000.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050469460.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050489987.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050482769.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050489999.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1"
XP_050483350.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050485132.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_050472250.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050484077.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050471139.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_050489051.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_050473386.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050476578.1	10	MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)"
XP_050481972.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050475686.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050473355.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050495355.1	11	Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631	"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility"
XP_050485045.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050490999.1	15	Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262	"T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_050469452.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050473123.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-114608	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation"
XP_050471262.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050472132.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase"
XP_050478859.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Neutrophil degranulation"
XP_050476095.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_050478803.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482766.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050479248.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_050470374.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050496362.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368082	"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"RORA activates gene expression"
XP_050476494.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_050496824.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050480494.1	24	KEGG: 05163+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"RSK activation";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Activation of AKT2";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway"
XP_050485164.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050490255.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050473822.1	5	Reactome: R-HSA-6804756;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599	"Regulation of TP53 Activity through Phosphorylation";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases"
XP_050486223.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050493775.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_050485766.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_050485705.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport"
XP_050481980.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"Neutrophil degranulation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050484418.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050471888.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050478741.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050479229.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050493373.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050480028.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_050495541.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050496589.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050479443.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69166	"DNA replication initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate"
XP_050484709.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050470891.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050482793.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050489275.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050496834.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050485295.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050484979.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050475193.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_050479785.1	2	MetaCyc: PWY-8061;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification II";"Phosphate bond hydrolysis by NUDT proteins"
XP_050470599.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050473061.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050487696.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050471476.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050492082.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050478830.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050486904.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_050488570.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
XP_050480092.1	24	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-202424;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"RSK activation";"FCERI mediated NF-kB activation";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"Activation of AKT2";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"Downstream TCR signaling";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"PI3K-Akt signaling pathway"
XP_050470302.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050481312.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050473399.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050490983.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050472248.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050483455.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7559	"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway"
XP_050470957.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050474722.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050489006.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050475582.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050491708.1	4	MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23	"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism"
XP_050488575.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_050470606.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050481982.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702	"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"UCH proteinases";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling"
XP_050473337.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050474285.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916	"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation"
XP_050489074.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050486765.1	10	KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"RSK activation";"Human cytomegalovirus infection";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway"
XP_050493227.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050469398.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050471794.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050476382.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_050488354.1	14	Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5656121	"Polymerase switching";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI"
XP_050495896.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050472851.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050471136.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050478502.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050478393.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050486941.1	5	Reactome: R-HSA-917937;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603	"Iron uptake and transport";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"Neddylation";"UCH proteinases"
XP_050487986.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050472743.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050469629.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050492534.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050481392.1	5	MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Methionine salvage pathway";"Cysteine and methionine metabolism";"Regulation of the apoptosome activity"
XP_050475144.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050496209.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050471810.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050471716.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050487973.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050471374.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050483760.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_050472469.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050491508.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Interleukin-7 signaling"
XP_050494384.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050483291.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050488162.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050486932.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050469584.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_050478243.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050495313.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_050483349.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050490283.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050491865.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050483393.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050482813.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050478928.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050489935.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_050481703.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050493286.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050483694.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050488668.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050473122.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Post-translational protein phosphorylation"
XP_050477637.1	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050480236.1	10	KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661	"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_050478016.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050491490.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes"
XP_050470585.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050482783.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050489659.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_050482859.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050493552.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050483125.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_050475234.1	56	Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050	"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_050485966.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050488251.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050479840.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway"
XP_050477659.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050491501.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_050485751.1	7	MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7886;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191	"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PC"
XP_050481227.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050483858.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050487273.1	10	MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7571;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10	"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Ferrichrome A biosynthesis";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Butanoate metabolism"
XP_050478570.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050479751.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050481184.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050474071.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920	"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Fatty acid degradation";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)"
XP_050481391.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_050477911.1	15	KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7218	"Pyruvate metabolism";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_050474816.1	11	Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670	"Hedgehog 'off' state";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway"
XP_050472489.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050480130.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050471312.1	4	Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I"
XP_050484197.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050488193.1	7	Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258	"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL"
XP_050482319.1	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling"
XP_050480926.1	11	KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-6545	"Pantothenate and CoA biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_050479028.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050482453.1	4	Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_050470756.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050472302.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050490500.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050474286.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050488547.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692	"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity"
XP_050487690.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8963889	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes"
XP_050469918.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050494244.1	10	MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I"
XP_050476902.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050479946.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050485653.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050476324.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050478053.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989	"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_050488192.1	7	Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"RHO GTPases Activate Formins"
XP_050482417.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050472121.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050485117.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_050489631.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_050477653.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050472155.1	16	Reactome: R-HSA-3134963;Reactome: R-HSA-209543;Reactome: R-HSA-1236974;Reactome: R-HSA-166058;Reactome: R-HSA-9020702;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-975138;Reactome: R-HSA-5602680;Reactome: R-HSA-1257604;Reactome: R-HSA-5602498;Reactome: R-HSA-1810476;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-975871;Reactome: R-HSA-975155	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"p75NTR recruits signalling complexes";"ER-Phagosome pathway";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Interleukin-1 signaling";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR5)";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome"
XP_050489459.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_050482659.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_050484949.1	5	MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism"
XP_050480233.1	10	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_050488173.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050481098.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050482864.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050490652.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050483385.1	20	MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)"
XP_050473434.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol"
XP_050494049.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_050487947.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_050484368.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050469580.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_050478132.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050476490.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050479934.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050477864.1	7	Reactome: R-HSA-5633231;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471;MetaCyc: PWY-6385;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6470	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)"
XP_050490495.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050492002.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)"
XP_050472824.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050475397.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6781823	"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex"
XP_050475478.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_050481679.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050482687.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050481647.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050482388.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050470961.1	9	Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897	"mTOR signalling";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes"
XP_050490919.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050486281.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050477165.1	26	Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-8866654;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-1362277;Reactome: R-HSA-110314;Reactome: R-HSA-4615885;Reactome: R-HSA-69091;Reactome: R-HSA-6804114;Reactome: R-HSA-110312;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397	"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Transcription of E2F targets under negative control by DREAM complex";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA replication proteins";"Polymerase switching";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by REV1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_050489611.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050478751.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050486169.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050484923.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_050490526.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_050493186.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050471638.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050480854.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_050479111.1	7	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
XP_050483723.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050496949.1	4	KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism"
XP_050472087.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation"
XP_050476009.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050493545.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050483166.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_050471695.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041	"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle"
XP_050473333.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050484671.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050483966.1	4	Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281	"Selenocysteine synthesis";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050472701.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_050479465.1	29	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome"
XP_050489511.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050491864.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050493063.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050475058.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism"
XP_050481890.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050470287.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050481426.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459	"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050485041.1	3	Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067	"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_050490404.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050478694.1	6	Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275	"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation"
XP_050493123.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050486867.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050477456.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050485439.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_050488872.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050477996.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050489016.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050472737.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050489064.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_050491408.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050494221.1	7	Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17	"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_050485294.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050496225.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_050492047.1	6	MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6118	"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerol degradation I";"Synthesis of PA";"Glycerol-3-phosphate shuttle"
XP_050478976.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050494370.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050483427.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050471581.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050487459.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050472166.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050482311.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050493712.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050490996.1	15	Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262	"T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_050493452.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_050496825.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050478757.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050489332.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050481231.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050489925.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050473924.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050485764.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_050472997.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050473327.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_050471260.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050489938.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050493119.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050490122.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050478619.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050482002.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-1433559	"Neddylation";"Regulation of KIT signaling"
XP_050469699.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050489502.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050490693.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050485261.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050484590.1	8	Reactome: R-HSA-5659996;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6;KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861	"RPIA deficiency: failed conversion of R5P to RU5P";"Rubisco shunt";"Pentose phosphate pathway";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050481996.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_050477326.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_050475516.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050487895.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825	"Platelet sensitization by LDL";"LDL clearance";"VLDL clearance";"VLDL assembly";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Chylomicron clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis"
XP_050470241.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050471239.1	18	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"mTORC1-mediated signalling";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050496489.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050476707.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050482551.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050490960.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050489537.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_050476850.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050473619.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050489457.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_050473945.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_050484984.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050491876.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050483582.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050473069.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050488215.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_050475199.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050470935.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050481486.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050474917.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050474996.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050472093.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050485740.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050493121.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050487949.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050493627.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050476096.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_050481313.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_050492524.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_050481881.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050485031.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050473895.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050488613.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_050478737.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050473376.1	12	KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1839117	"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Human papillomavirus infection";"NRAGE signals death through JNK";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by FGFR1 in disease";"Human cytomegalovirus infection";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050479891.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050475556.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050494245.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050473969.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050493708.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050476000.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050472781.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050470407.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050485174.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050484878.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_050478804.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482318.1	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050487143.1	12	MetaCyc: PWY-6672;MetaCyc: PWY-5108;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1	"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Methane metabolism";"Lupulone and humulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism"
XP_050494036.1	7	KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7184	"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_050486170.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050471481.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050471341.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050493596.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050493609.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050492496.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050471448.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050484102.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050474741.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050486026.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050470710.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050487831.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050488242.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_050493019.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050477055.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Circadian Clock";"snRNP Assembly";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)"
XP_050485846.1	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_050470691.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_050492874.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050486252.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050484318.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_050493614.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050482699.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_050485589.1	52	Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-6781827	"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_050476361.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_050495039.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050494733.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050476230.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050477447.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050486010.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050486848.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050483646.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050491232.1	7	MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824	"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis"
XP_050488945.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050491603.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050475689.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_050476577.1	10	MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis IV (plant cytosol)"
XP_050470034.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050478297.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin"
XP_050492461.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050485130.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_050478283.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050478230.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050477609.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952	"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions"
XP_050471161.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050491988.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050491261.1	3	MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581	"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050475472.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050469586.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050474798.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050484188.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050477271.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050493110.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050487573.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_050493086.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange"
XP_050485655.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050492117.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_050490819.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050476496.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050493497.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050494129.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_050469594.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050486615.1	5	KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;MetaCyc: PWY-5531;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_050496314.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050477289.1	6	Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210	"Mitochondrial protein import";"Oxidative phosphorylation";"ATP biosynthesis";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling"
XP_050487409.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_050481475.1	16	Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558	"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"G alpha (q) signalling events";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_050484688.1	6	MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis"
XP_050490981.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050474770.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050493281.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_050471003.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050472714.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050477194.1	9	MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70171	"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis"
XP_050480186.1	24	Reactome: R-HSA-354192;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-2730905;Reactome: R-HSA-202424;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5218921;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1	"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Activation of AKT2";"Human papillomavirus infection";"FCERI mediated NF-kB activation";"VEGFR2 mediated cell proliferation";"Human immunodeficiency virus 1 infection";"RSK activation";"Human cytomegalovirus infection"
XP_050487704.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050485017.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050484156.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050487333.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050470733.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050488540.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050491554.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050480825.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050486237.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_050472387.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050489157.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050494778.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050487742.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050484535.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482758.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_050479241.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050492346.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050482390.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050492383.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050478720.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861	"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Recycling pathway of L1";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly"
XP_050486017.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050487777.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050496463.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_050469623.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050478551.1	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
XP_050491743.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1"
XP_050484475.1	26	Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320	"Recycling pathway of L1";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes"
XP_050486045.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050486789.1	7	KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;MetaCyc: PWY-6074;MetaCyc: PWY-7154;Reactome: R-HSA-191273;Reactome: R-HSA-9022692;MetaCyc: PWY-2541	"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Zymosterol biosynthesis";"Ergosterol biosynthesis II";"Cholesterol biosynthesis";"Regulation of MECP2 expression and activity";"Phytosterol biosynthesis (plants)"
XP_050482803.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050485803.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050477296.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050493096.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050478591.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050469696.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050477658.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050490918.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_050483781.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050469530.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050472739.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050494763.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050472319.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050484862.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_050494773.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050479239.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050489830.1	9	KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)"
XP_050491443.1	10	Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"Translation initiation complex formation"
XP_050493084.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050470308.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050472881.1	5	Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-212300	"DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA"
XP_050488718.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050492184.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_050469848.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050482765.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050481460.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_050470097.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_050482816.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050493989.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050496802.1	11	MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-109704	"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"Macroautophagy";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade"
XP_050474755.1	18	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-5689901;Reactome: R-HSA-1221632;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"Metalloprotease DUBs";"Meiotic synapsis";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint"
XP_050477618.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066	"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_050482472.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050477290.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670	"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway"
XP_050493374.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050475763.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050479156.1	5	KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Cysteine and methionine metabolism";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_050484829.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050490564.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_050492342.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050497077.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700	"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling"
XP_050485023.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050486612.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091	"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells"
XP_050478249.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050496365.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha"
XP_050488753.1	4	MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975	"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate"
XP_050485514.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050485536.1	5	Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198	"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs"
XP_050484694.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920	"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_050472498.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050481474.1	16	Reactome: R-HSA-114604;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-512988	"GPVI-mediated activation cascade";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"RET signaling";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_050472395.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050485940.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050490721.1	5	MetaCyc: PWY-6012;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1;MetaCyc: PWY-6289;Reactome: R-HSA-199220	"Acyl carrier protein metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein activation";"Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism"
XP_050488539.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050475565.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050479795.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6807505	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes"
XP_050481989.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_050491487.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050496843.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_050470114.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050479673.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_050490654.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050488495.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050478813.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050488318.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050472623.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050491989.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050491240.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation"
XP_050477193.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050471515.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050481018.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050491699.1	6	Reactome: R-HSA-2046106;Reactome: R-HSA-1369062;Reactome: R-HSA-2046105;Reactome: R-HSA-9603798;Reactome: R-HSA-5684045;Reactome: R-HSA-390247	"alpha-linolenic acid (ALA) metabolism";"ABC transporters in lipid homeostasis";"Linoleic acid (LA) metabolism";"Class I peroxisomal membrane protein import";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids"
XP_050476594.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_050470545.1	4	KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4	"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism"
XP_050492699.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5872;MetaCyc: PWY-6708;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_050469569.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_050481103.1	6	Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation"
XP_050473623.1	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_050494068.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_050470158.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050490055.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050479245.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_050478017.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050492729.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050472438.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050481039.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050476105.1	16	Reactome: R-HSA-2046105;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-2046106;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041	"Linoleic acid (LA) metabolism";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"alpha-linolenic acid (ALA) metabolism";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_050475593.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050488229.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050475479.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050469612.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050487964.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_050490814.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050474769.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050487627.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050480135.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050477445.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050469392.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493787.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050483063.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050485438.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_050476969.1	4	MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism"
XP_050485047.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050473688.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050495127.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_050484193.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050493141.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050474832.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050482809.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050488095.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_050470434.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050476903.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050489038.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050485407.1	17	Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-6679;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-196780	"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Biotin transport and metabolism"
XP_050482784.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050470719.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_050470242.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050475674.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_050486292.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_050472009.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050480274.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050486639.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050474516.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050483915.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-7383;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1	"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"D-Alanine metabolism"
XP_050478724.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050471759.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050489090.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050478084.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050493219.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050487045.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050488437.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050475664.1	11	MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-3861;Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;KEGG: 00051+5.3.1.8	"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Mannitol degradation II";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism"
XP_050491223.1	29	Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135	"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER"
XP_050479982.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050481606.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050493161.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_050472627.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050489850.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050483727.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050489805.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_050488958.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_050472585.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050493229.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050492953.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050483791.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667	"Synthesis of PA";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I"
XP_050482335.1	5	KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451	"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_050472853.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_050484325.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050483344.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050470005.1	10	MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613	"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Folate transformations I";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_050478113.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050480832.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_050493190.1	10	MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7187;MetaCyc: PWY-3841;Reactome: R-HSA-69205;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7199	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleosides salvage"
XP_050489285.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050482099.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_050482005.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_050489533.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050476876.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050494382.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050488356.1	33	Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-69202;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-167158	"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex"
XP_050481963.1	8	MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168	"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)"
XP_050477270.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050469462.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050489501.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050490473.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050487201.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_050471218.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012	"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050486849.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050489019.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050473022.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050488265.1	7	MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25	"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis"
XP_050476687.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050486312.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_050487283.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050483498.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050481674.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050494270.1	3	MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17	"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism"
XP_050482340.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050484007.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050474467.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-6784531	"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus"
XP_050485691.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events"
XP_050473195.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050488339.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050471616.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
XP_050476319.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050472730.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050476252.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050470768.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050472936.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050471224.1	11	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-383280	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway"
XP_050472882.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050470608.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050478726.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050477000.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050494381.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050494391.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050490800.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050496951.1	4	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050492774.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050486029.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050491742.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-83936	"Cytosolic iron-sulfur cluster assembly";"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050484834.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050480590.1	19	Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825	"VLDL assembly";"Platelet sensitization by LDL";"LDL clearance";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"LDL remodeling";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Chylomicron assembly";"Chylomicron clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis"
XP_050470552.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050491644.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050484319.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_050476107.1	16	MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;Reactome: R-HSA-2046106;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-2046105	"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"alpha-linolenic acid (ALA) metabolism";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Linoleic acid (LA) metabolism"
XP_050470447.1	29	Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823	"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050490408.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050473779.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050481761.1	14	Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314	"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Polymerase switching";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050489498.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050486064.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050487108.1	10	MetaCyc: PWY-5892;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895;MetaCyc: PWY-7996;MetaCyc: PWY-5891;MetaCyc: PWY-5839;MetaCyc: PWY-5890;Reactome: R-HSA-2142789;MetaCyc: PWY-5844;MetaCyc: PWY-5849	"Menaquinol-12 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis"
XP_050486423.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-202424	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling"
XP_050477607.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-111932	"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB"
XP_050497118.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050486253.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_050474135.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050491828.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_050481805.1	6	MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism"
XP_050472001.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050481904.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050479385.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050484005.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050485025.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050471537.1	25	Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-8941326;Reactome: R-HSA-8941284;Reactome: R-HSA-8951911;Reactome: R-HSA-8934593;Reactome: R-HSA-8939247;Reactome: R-HSA-8939245;Reactome: R-HSA-8877330;Reactome: R-HSA-8935964;Reactome: R-HSA-8941333;Reactome: R-HSA-8939256;Reactome: R-HSA-9018519;Reactome: R-HSA-8931987;Reactome: R-HSA-8949275;Reactome: R-HSA-8941332;Reactome: R-HSA-8939243;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-8878166;Reactome: R-HSA-8939242;Reactome: R-HSA-8941858;Reactome: R-HSA-8951936;Reactome: R-HSA-8939246;Reactome: R-HSA-8939902	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates bone development";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates RUNX1-mediated transcription";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in WNT signaling";"Estrogen-dependent gene expression";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates genes involved in cell migration";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX3 expression and activity";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX2 expression and activity"
XP_050486051.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050489106.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050476356.1	5	MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3	"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism"
XP_050493794.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050473972.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050479466.1	29	Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76042	"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050485373.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_050476630.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_050487636.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050483795.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_050486442.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050481941.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050474560.1	6	KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-6731;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941	"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II"
XP_050487058.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050493774.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_050474728.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050476234.1	5	Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656253	"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_050478507.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation"
XP_050493282.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_050490455.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050484367.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050483313.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135	"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation"
XP_050495095.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050477067.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs"
XP_050493002.1	12	KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4	"Purine metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Selenate reduction";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Monobactam biosynthesis"
XP_050473729.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050480258.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050483124.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_050485507.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050472283.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050472768.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050473991.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050493704.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050473915.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050477862.1	13	MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5	"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Propanoate metabolism"
XP_050483037.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_050483342.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050481962.1	8	MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168	"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)"
XP_050491000.1	15	Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated"
XP_050487632.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050481233.1	33	Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276	"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways"
XP_050479672.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050469669.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050489685.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050484908.1	7	Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133	"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1"
XP_050485678.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"Aggrephagy";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050476059.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050489540.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_050477784.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050470280.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050491958.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128	"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling"
XP_050494119.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050472465.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050487568.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050489002.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_050473982.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050478744.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050474000.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050472375.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050482549.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050470466.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_050484537.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050472258.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050483563.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050477535.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050469424.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050490571.1	10	Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6804756	"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation"
XP_050470573.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050476884.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050474001.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050471357.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050476678.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050496432.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050489886.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852	"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy"
XP_050492458.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050484922.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050487576.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_050485863.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050479860.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050496487.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050480278.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050485657.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050475462.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050482316.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050493290.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050480310.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050478144.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_050485063.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050469390.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050478506.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050482729.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050469961.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050492994.1	12	MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4	"Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism"
XP_050478957.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_050481664.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050493140.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050472300.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport"
XP_050481906.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050496145.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050484306.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050489968.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_050489337.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis"
XP_050492355.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050486810.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050477697.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050493101.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050480738.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050485769.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_050484966.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050488880.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050493945.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050477138.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050480728.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050478566.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050488280.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050489274.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050473016.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050479867.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050474563.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_050480252.1	10	Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661	"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_050492932.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050487051.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050477463.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050485660.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism"
XP_050482629.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050491657.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050480711.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050471222.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050486893.1	8	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6"
XP_050493225.1	10	KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357956;Reactome: R-HSA-5357905;KEGG: 05170+2.7.11.1	"T cell receptor signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling";"Human immunodeficiency virus 1 infection"
XP_050471914.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050474894.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_050473858.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1";"Ion channel transport";"Photosynthesis";"Transferrin endocytosis and recycling"
XP_050471352.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050490733.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050493145.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;Reactome: R-HSA-1660517;KEGG: 00562+3.1.3.64;KEGG: 04070+3.1.3.64	"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050485379.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050491027.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050492727.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050471860.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050473635.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695	"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Neutrophil degranulation"
XP_050483534.1	3	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_050469953.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050472526.1	17	Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-69091	"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching"
XP_050469963.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050488174.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050476743.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050495607.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_050492467.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050493802.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788	"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC"
XP_050496695.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_050487020.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-9657050;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5649702	"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Defective OGG1 Localization";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050472810.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_050493509.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050479856.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050491229.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression"
XP_050476244.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_050469595.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050485046.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050492513.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050477464.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050474050.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050485693.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050485156.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050484504.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050493471.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050482229.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050478986.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050473053.1	18	MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;Reactome: R-HSA-499943;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220	"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_050471669.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050488554.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_050472243.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050484375.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050472778.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050485993.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_050473389.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050482555.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050484486.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050470601.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050472138.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_050472247.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050475829.1	10	Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-3821	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification"
XP_050475062.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050475635.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050492384.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_050478045.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852	"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy"
XP_050477399.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_050480270.1	24	KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218921;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"RSK activation";"VEGFR2 mediated cell proliferation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Activation of AKT2";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"Downstream TCR signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation";"Thermogenesis";"CLEC7A (Dectin-1) signaling";"Relaxin signaling pathway"
XP_050479547.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050482054.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050477602.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066	"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_050493804.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_050484961.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050483281.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050471250.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050490299.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_050480788.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050489327.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_050470326.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050472939.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050482008.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050488357.1	33	Reactome: R-HSA-112382;Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-69231;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-69202	"Formation of RNA Pol II elongation complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition"
XP_050476875.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050480774.1	17	Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-174414;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-69183	"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Processive synthesis on the C-strand of the telomere";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand"
XP_050484238.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050472051.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050488492.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442	"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog 'on' state";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs"
XP_050489480.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050482420.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050487014.1	12	MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4	"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism"
XP_050483353.1	5	KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3	"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)"
XP_050482833.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_050484406.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050493284.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050475767.1	2	Reactome: R-HSA-975634;Reactome: R-HSA-192456	"Retinoid metabolism and transport";"Digestion of dietary lipid"
XP_050470534.1	4	Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030	"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis"
XP_050486318.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050486649.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050475642.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050489046.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_050488239.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050494017.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050477644.1	9	Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3642279	"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer"
XP_050494804.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050470774.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050473027.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050477807.1	3	MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996	"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_050496927.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050482514.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050481872.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050485999.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_050472740.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050485253.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050488763.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050476545.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_050474915.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050472750.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050486460.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050472370.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050493221.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050483613.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria"
XP_050471217.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_050481877.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050496403.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050497053.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_050490812.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050474814.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050485749.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050476779.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050478207.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553	"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Neddylation";"Regulation of expression of SLITs and ROBOs"
XP_050497048.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050489287.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050477269.1	9	Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-68962	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Polymerase switching";"DNA replication initiation";"Activation of the pre-replicative complex"
XP_050496162.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050479226.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050480959.1	6	MetaCyc: PWY-5497;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442	"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis"
XP_050475195.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation"
XP_050496836.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050492457.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050488176.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050489644.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050470117.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050494058.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_050483458.1	13	MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690	"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)"
XP_050470237.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050470718.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050487480.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_050476954.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050471851.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_050493667.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050474667.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress"
XP_050477413.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050486619.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_050490580.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_050477034.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050470693.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-159231	"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_050474508.1	10	KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Other glycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
XP_050491461.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050494651.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050487924.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050472127.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050472809.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050473950.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050482878.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050492897.1	6	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-204005	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport"
XP_050489988.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050491921.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_050494006.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050470304.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050472149.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_050471092.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050474677.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-8854518	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"AURKA Activation by TPX2"
XP_050469817.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050486788.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050475948.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050493711.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050486853.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050491820.1	33	Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-159231	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_050489778.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050470381.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050484515.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050479637.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050478590.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050478601.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050472027.1	9	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050469748.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport"
XP_050484880.1	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_050495415.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_050471920.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050473941.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_050487019.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050478481.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050484251.1	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798	"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell"
XP_050478814.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050474754.1	18	Reactome: R-HSA-5693565;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-5689901;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"Metalloprotease DUBs";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050484381.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_050492521.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050483503.1	3	Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078	"GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_050485491.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-9620244	"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Long-term potentiation"
XP_050478387.1	8	Reactome: R-HSA-6787639;MetaCyc: PWY-5739;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-7573	"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis"
XP_050479929.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050493955.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050480133.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050472135.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_050491286.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050491189.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050492965.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050471396.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_050481681.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050474217.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-3238698	"Neutrophil degranulation";"WNT ligand biogenesis and trafficking"
XP_050473162.1	9	Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-442982	"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050474668.1	4	Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-176187	"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress"
XP_050496413.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_050493612.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050483799.1	10	Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264	"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
XP_050488027.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050491478.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861	"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Recycling pathway of L1";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly"
XP_050478459.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050475083.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050480766.1	17	Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER"
XP_050482003.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_050485186.1	17	MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-7383;MetaCyc: PWY-5392;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methylaspartate cycle";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)"
XP_050493747.1	7	Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484	"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_050492364.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050470605.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050478977.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050491873.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050485013.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050477943.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050482626.1	7	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22	"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_050470274.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050490000.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1"
XP_050492123.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_050477458.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050488461.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050481644.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050477468.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050492313.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050481175.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050480547.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_050471264.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050484015.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050481315.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-9634638	"MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_050477311.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050492591.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050475481.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720	"Hedgehog 'off' state";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_050488881.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050492278.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition"
XP_050476227.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050480991.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-1989781	"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression"
XP_050474561.1	6	MetaCyc: PWY-6731;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-7238	"Starch degradation III";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II"
XP_050481756.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Polymerase switching";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK"
XP_050480993.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168	"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)"
XP_050487620.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050487708.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_050480755.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation"
XP_050485965.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050495810.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050493139.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050486300.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050480795.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_050481507.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050489859.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050475181.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_050481202.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050484970.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050479271.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050487054.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176412	"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C"
XP_050478727.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050479223.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050493254.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050481169.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050482169.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050487461.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050472473.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050471632.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080	"Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)"
XP_050474076.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_050483936.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)"
XP_050482276.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050497083.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_050493401.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050478259.1	8	KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050481649.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050480374.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050482964.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050470073.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050486636.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050483084.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation"
XP_050492477.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050492561.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050481012.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050487267.1	4	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis"
XP_050492237.1	12	KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932	"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction"
XP_050480257.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050482914.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050470805.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214	"Macroautophagy";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs"
XP_050486933.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050494199.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050471751.1	10	Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111458	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome"
XP_050483286.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050484547.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050473191.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050484248.1	7	Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-373080	"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)"
XP_050494126.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050481323.1	17	Reactome: R-HSA-112382;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167152	"Formation of RNA Pol II elongation complex";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_050490042.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050486283.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050493069.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050485449.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050488056.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050476384.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity"
XP_050482648.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050491940.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050484626.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050477223.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050480818.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050495074.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050473780.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050486967.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050480303.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050488382.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050491214.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-389513	"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling"
XP_050493391.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050486452.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050488563.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_050487968.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050493091.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050475309.1	6	KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817	"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_050490907.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050492538.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050485251.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050492372.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050475475.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050475497.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050487878.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D"
XP_050487278.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-532668;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_050491444.1	10	Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"Translation initiation complex formation"
XP_050493506.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050482094.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050480507.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050491224.1	29	Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050476573.1	14	Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;MetaCyc: PWY-6453	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Synthesis of PC";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Synthesis of PE";"Anandamide biosynthesis II";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis"
XP_050471897.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050485154.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050483405.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050492954.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050482760.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050480124.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050486798.1	5	Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409	"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation"
XP_050485352.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050471639.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050479592.1	8	Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111458	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"Formation of apoptosome"
XP_050493666.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050496609.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050476716.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050489334.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins";"MHC class II antigen presentation"
XP_050469600.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050487266.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050487753.1	52	Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-76071;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242	"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_050469916.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050487694.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050478381.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_050472204.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050489867.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050490457.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050487810.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050497084.1	7	Reactome: R-HSA-2173795;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-3108214	"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins"
XP_050481794.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050485732.1	10	MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70263;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis"
XP_050470325.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050484693.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050476683.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
XP_050470079.1	14	Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-113418	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex"
XP_050497104.1	8	KEGG: 00030+2.2.1.2;MetaCyc: PWY-1861;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;Reactome: R-HSA-8950505	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050479554.1	9	Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_050493600.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_050493341.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050489683.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_050482380.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_050474998.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_050469911.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_050472652.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050493613.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050475014.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050471256.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_050472237.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050494332.1	3	Reactome: R-HSA-1660499;KEGG: 04660+2.7.10.2;Reactome: R-HSA-111465	"Synthesis of PIPs at the plasma membrane";"T cell receptor signaling pathway";"Apoptotic cleavage of cellular proteins"
XP_050469958.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050486420.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050487980.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050478715.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050473616.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050494772.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050490306.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_050487046.1	5	Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233	"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway"
XP_050491078.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050477999.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_050488647.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050491410.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_050474389.1	11	MetaCyc: PWY-6538;MetaCyc: PWY-5497;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-6596;MetaCyc: PWY-6606;KEGG: 00232+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2	"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Drug metabolism - other enzymes";"Theophylline degradation";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Caffeine metabolism";"Purine metabolism"
XP_050492924.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050491624.1	5	Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097	"p38MAPK events";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway"
XP_050487374.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050485872.1	14	Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-1474228;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Degradation of the extracellular matrix";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells"
XP_050490370.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_050483320.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation"
XP_050492514.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050488373.1	18	Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4	"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism"
XP_050470410.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050476908.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050486959.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050492750.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway"
XP_050470697.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050469775.1	28	Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5696395;Reactome: R-HSA-110314	"Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"HSF1 activation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050487747.1	52	Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-76071;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-167152;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5617472	"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050491360.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-389977	"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Recycling pathway of L1";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway"
XP_050494193.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050475662.1	11	MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8	"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_050482270.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050493595.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050484256.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050483617.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050486653.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_050471067.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050474895.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_050496461.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050473223.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050486533.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050485753.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-7818	"Glycerophospholipid metabolism";"Synthesis of PC";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_050486856.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050487842.1	11	Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_050492714.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050483789.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7411	"Synthesis of PA";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)"
XP_050491847.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050472146.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_050490244.1	24	Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-416476	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events"
XP_050472606.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_050494100.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050476094.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_050476235.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1963640;Reactome: R-HSA-1251985;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB4";"PI3K events in ERBB2 signaling"
XP_050473797.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_050472188.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050472628.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050493549.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050475590.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050480358.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050477285.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_050476359.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_050491799.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050483408.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050478265.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050480337.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-2129379	"Digestion of dietary carbohydrate";"Molecules associated with elastic fibres"
XP_050487056.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050488713.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050494459.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050478844.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050479125.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050477264.1	9	Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-69166	"DNA replication initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate"
XP_050470952.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_050494372.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050493094.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050493088.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050487733.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050477590.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892	"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation"
XP_050470178.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_050488043.1	16	Reactome: R-HSA-70263;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-1622;MetaCyc: PWY-7124;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7218	"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_050493525.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050474806.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050484832.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050476945.1	8	Reactome: R-HSA-1855183;KEGG: 00562+5.5.1.4;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6372;MetaCyc: PWY-2301;MetaCyc: PWY-4661;MetaCyc: PWY-6664	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis"
XP_050477787.1	12	Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events"
XP_050471872.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050476521.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_050475250.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events"
XP_050478743.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050485878.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050487040.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_050496889.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_050482794.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050476093.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_050492796.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_050470469.1	10	Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162	"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape"
XP_050486926.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism"
XP_050485555.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_050476563.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_050486715.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050472097.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050490447.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050472390.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050492485.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_050490070.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050491950.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050470159.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050470532.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050477146.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050481173.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050475402.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050475105.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490	"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation"
XP_050485610.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050492835.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050475059.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock"
XP_050497091.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_050493108.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050480670.1	57	Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276	"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Neddylation";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_050472664.1	17	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Translation initiation complex formation"
XP_050495130.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050483073.1	8	KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050469950.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050496213.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568	"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase"
XP_050493129.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050483322.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948	"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants"
XP_050472554.1	3	KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_050487244.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_050472769.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493791.1	13	Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8856828	"VLDLR internalisation and degradation";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"Clathrin-mediated endocytosis"
XP_050470861.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050471514.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050496988.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050485635.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_050486081.1	42	KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-7216;MetaCyc: PWY-5789;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-5138;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7778;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-6945;MetaCyc: PWY-7779;MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7401;KEGG: 00623+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-6883;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7606;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6944;MetaCyc: PWY-1361;MetaCyc: PWY-5109;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-7726	"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Butanoate metabolism";"Fatty acid degradation";"Fatty acid degradation";"Fatty acid elongation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Tryptophan metabolism";"Butanoate metabolism";"Pyruvate fermentation to butanol I";"2-methylpropene degradation";"Phenylalanine metabolism";"Fatty acid salvage";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Aminobenzoate degradation";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Toluene degradation";"Caprolactam degradation";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol II (engineered)";"Geraniol degradation";"Spodoptera littoralis pheromone biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Limonene and pinene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Benzoyl-coa degradation I (aerobic)";"Fermentation to 2-methylbutanoate";"Benzoate degradation";"Pyruvate fermentation to hexanol (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_050481095.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050478593.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050488822.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050495839.1	21	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7221;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7219;MetaCyc: PWY-7205	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"CMP phosphorylation"
XP_050497028.1	14	MetaCyc: PWY-5101;MetaCyc: PWY-5104;MetaCyc: PWY-5057;MetaCyc: PWY-7767;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5076;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103	"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"L-leucine degradation III";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III"
XP_050485521.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050484246.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050488812.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_050485027.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050486001.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_050482159.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050478568.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050477150.1	17	MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6627;MetaCyc: PWY-6608;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644	"Guanine and guanosine salvage";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Purine catabolism";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis"
XP_050490818.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050482419.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050490971.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050479890.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050479338.1	26	Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-400253	"Attenuation phase";"RUNX3 regulates NOTCH signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"Circadian Clock"
XP_050487984.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050480810.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050494378.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050479633.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_050489865.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050473722.1	5	KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_050480783.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050473781.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050472523.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050476568.1	8	Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-8953750	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Formation of apoptosome";"Transcriptional Regulation by E2F6"
XP_050470314.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050488866.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050474005.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_050485389.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050490627.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895	"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_050490816.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050474836.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050483749.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050473615.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050492512.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050483628.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050487572.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation"
XP_050479469.1	3	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050496610.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050472207.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050480913.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050474720.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050474562.1	6	KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-6731;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-5941	"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation III";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II"
XP_050490988.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050475110.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_050487483.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_050474771.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050484770.1	6	MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6922	"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_050487745.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050476229.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050470008.1	4	MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-7285;MetaCyc: PWY-6829	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis";"Trna methylation (yeast)"
XP_050480635.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050472883.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050486568.1	52	Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091	"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells"
XP_050488148.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050489465.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050474371.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050487699.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050477888.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050479985.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050494204.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_050486016.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050478197.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397	"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_050482172.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050473922.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050470214.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050479600.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050487460.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050486390.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050470377.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050483438.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050473905.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050483524.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_050485656.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050487923.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC"
XP_050492574.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_050471847.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050484146.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050494212.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_050480080.1	9	MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664	"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_050491938.1	11	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Ub-specific processing proteases";"Transcription of the HIV genome";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050482623.1	7	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22	"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_050493124.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050476972.1	4	KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_050474497.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050479520.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis"
XP_050478471.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050478821.1	14	Reactome: R-HSA-500657;Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-434316;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-399997;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-418217	"Presynaptic function of Kainate receptors";"Ca2+ pathway";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G beta:gamma signalling through PLC beta"
XP_050469525.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050486053.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050485537.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050471060.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_050481993.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050492391.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050484638.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050474058.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050493430.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050489196.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome"
XP_050493090.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050488191.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050487458.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050493380.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050490401.1	13	Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325	"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_050479382.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050475212.1	9	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection"
XP_050496614.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050492124.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_050477812.1	3	MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996	"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_050482483.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050483530.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050496521.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050494852.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050488879.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050477517.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050495046.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050471866.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_050478486.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025	"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions"
XP_050490360.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050491076.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050485406.1	17	Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6679;Reactome: R-HSA-163765;Reactome: R-HSA-200425	"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Carnitine metabolism"
XP_050489736.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_050487705.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050479831.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050496066.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_050475173.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050481013.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050470908.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-7736	"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis"
XP_050486648.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050475012.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050478595.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050488374.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416	"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Synthesis of PA";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_050491749.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_050491961.1	16	Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050477225.1	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050481796.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_050489076.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050481876.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050482491.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050469625.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050476360.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events"
XP_050490998.1	15	Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated"
XP_050469558.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050484848.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_050486677.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050474605.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050477754.1	16	Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-75955	"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Neddylation";"Pausing and recovery of HIV elongation";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation"
XP_050496897.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050494760.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050488957.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_050482546.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050491834.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050475801.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050491956.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050478548.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_050493664.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050475584.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_050477366.1	5	Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-7863;KEGG: 00740+2.7.1.26;MetaCyc: PWY-5523	"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis";"Riboflavin metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)"
XP_050489484.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050496585.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050479976.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050478919.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-8950505;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium"
XP_050482444.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050482279.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050472131.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase"
XP_050473832.1	31	Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-7723;MetaCyc: PWY-5994;Reactome: R-HSA-199220;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-6113;Reactome: R-HSA-75105;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6519;Reactome: R-HSA-163765;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;MetaCyc: PWY-5366;MetaCyc: PWY-7664;MetaCyc: PWYG-321;MetaCyc: PWY-6799;MetaCyc: PWY-7746;MetaCyc: PWY-7663;MetaCyc: PWY-6282	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Biotin metabolism";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mycobacterial sulfolipid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)"
XP_050490980.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050476795.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050491392.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050472139.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_050485390.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050479150.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050492573.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange"
XP_050481037.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050476315.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050482482.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050475677.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050482780.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050479148.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050471295.1	8	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins"
XP_050473939.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050475961.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050472267.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050486000.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050471640.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050491741.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050493230.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050474215.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-6798695	"WNT ligand biogenesis and trafficking";"Neutrophil degranulation"
XP_050492528.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050487487.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_050494246.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050482559.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050487784.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050493472.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050490597.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050487707.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050474052.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050493288.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050481322.1	17	Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-112382;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050479806.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043	"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events"
XP_050473402.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050484842.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050483039.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050476785.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050485827.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050473252.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050481444.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_050470320.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050470450.1	29	Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167160	"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_050486167.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_050475030.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050497130.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050493232.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050497061.1	22	MetaCyc: PWY-8013;MetaCyc: PWY-6142;Reactome: R-HSA-6798695;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-7347;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9;Reactome: R-HSA-70263;KEGG: 00500+5.3.1.9;MetaCyc: PWY-622;MetaCyc: PWY-6981;MetaCyc: PWY-5514;MetaCyc: PWY-5659;MetaCyc: PWY-5384;Reactome: R-HSA-5628897;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-3801;MetaCyc: PWY-5054;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Neutrophil degranulation";"Pentose phosphate pathway";"1,5-anhydrofructose degradation";"Sucrose biosynthesis III";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism";"Gluconeogenesis";"Starch and sucrose metabolism";"Starch biosynthesis";"Chitin biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"GDP-mannose biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"TP53 Regulates Metabolic Genes";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Sucrose degradation II (sucrose synthase)";"D-sorbitol biosynthesis I";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis"
XP_050492998.1	12	Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction";"Purine metabolism"
XP_050479802.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398	"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Ca2+ pathway"
XP_050484473.1	26	Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"HCMV Early Events"
XP_050486793.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_050471416.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050486342.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050474015.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_050496922.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050487830.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050490703.1	4	Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_050483380.1	20	KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340	"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_050477906.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325	"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis"
XP_050488316.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050475190.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_050486973.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050485378.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050494014.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050491853.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050471428.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050480815.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050486925.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_050481990.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_050477226.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling"
XP_050477056.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Circadian Clock";"snRNP Assembly";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)"
XP_050475150.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050482393.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_050492362.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050475567.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050476913.1	12	MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4	"Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Selenate reduction";"Selenocompound metabolism"
XP_050482026.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050469433.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050486396.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050482239.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050485148.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050489779.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050483925.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050491445.1	2	Reactome: R-HSA-8934593;Reactome: R-HSA-69231	"Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1"
XP_050492350.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050475349.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050475482.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050494208.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050470531.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050469401.1	4	Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping"
XP_050496435.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050470887.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050472010.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050476592.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_050489323.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050470139.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050486262.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050472818.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_050492443.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050485300.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050480883.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_050478390.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050469457.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050496587.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050471817.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050494064.1	5	Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253	"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_050496965.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050495532.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050481799.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050485345.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050481329.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050487886.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050470624.1	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)"
XP_050472234.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050481162.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050486438.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050470315.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050496856.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050481461.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_050486692.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050486851.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050494002.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050486549.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_050494223.1	7	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050482028.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050496821.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050489050.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_050477080.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050474430.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050481298.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050474721.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050487577.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_050480827.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050481988.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050491750.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050484686.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_050480323.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050482763.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050479799.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509	"Ca2+ pathway";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling"
XP_050477087.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050485165.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050470553.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050496357.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050477466.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050471065.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050479914.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050475056.1	6	Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16	"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050493515.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050477885.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_050477259.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050482101.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050477599.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050474631.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_050473350.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050483470.1	13	MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5537	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V"
XP_050471005.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050490566.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050496485.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050491423.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050494334.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050494035.1	11	MetaCyc: PWY-5123;MetaCyc: PWY-7524;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7560;MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7102;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-191273	"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway III (archaea)";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis"
XP_050476155.1	4	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism"
XP_050478001.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050488044.1	16	MetaCyc: PWY-1622;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-7124;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-8004	"Formaldehyde assimilation I (serine pathway)";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I"
XP_050470339.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050492045.1	6	MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6118	"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle"
XP_050494067.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_050470662.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050488430.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050474179.1	3	KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741	"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050472378.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050471764.1	5	KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39	"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism"
XP_050475043.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050475552.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050475176.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050493703.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_050485701.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050483127.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050482993.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050484560.1	26	Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497	"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050493758.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050492456.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_050494041.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_050491809.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050479584.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050477710.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050475480.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_050486634.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II"
XP_050478621.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050483009.1	5	MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050493849.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050493868.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_050476745.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050496072.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050470855.1	9	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315	"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol"
XP_050482873.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050474421.1	7	KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2	"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis"
XP_050485650.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527	"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation"
XP_050476579.1	10	KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861	"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050482067.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050490687.1	12	Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050487965.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_050489007.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050478379.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050469453.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050485445.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050490268.1	6	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-5269;MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5	"Synthesis of PG";"Synthesis of PA";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_050475168.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050484380.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_050473390.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050496591.1	6	MetaCyc: PWY-6906;MetaCyc: PWY-7395;MetaCyc: PWY-7077;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25	"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism"
XP_050482119.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050488434.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins"
XP_050494220.1	7	Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17	"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_050475308.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_050481205.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050472080.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_050480962.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050475082.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_050470007.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050470919.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050470077.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050490016.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955	"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation"
XP_050473157.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050482206.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050487722.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_050484402.1	9	Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616	"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication"
XP_050484019.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050483437.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050477846.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_050496486.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050496381.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050475656.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050485520.1	13	Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-1650814;Reactome: R-HSA-186797	"Anchoring fibril formation";"NCAM1 interactions";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Collagen degradation";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Extracellular matrix organization";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF"
XP_050485994.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050473106.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050491703.1	4	MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662	"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism"
XP_050476786.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050478474.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050470167.1	5	Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853	"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)"
XP_050492352.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050493379.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050477671.1	33	KEGG: 00260+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-6313;MetaCyc: PWY-7013;MetaCyc: PWY-7111;MetaCyc: PWY-6333;MetaCyc: PWY-5079;KEGG: 00626+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5751;MetaCyc: PWY-5480;MetaCyc: PWY-6342;MetaCyc: PWY-5082;MetaCyc: PWY-5486;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-7396;MetaCyc: PWY-6587;KEGG: 00071+1.1.1.1;MetaCyc: PWY-1801;KEGG: 00625+1.1.1.1;KEGG: 00010+1.1.1.1;KEGG: 00592+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-6802;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00680+1.1.1.284;MetaCyc: PWY-3162;MetaCyc: PWY-6871;MetaCyc: PWY-5057	"Glycine, serine and threonine metabolism";"Retinol metabolism";"L-leucine degradation III";"Serotonin degradation";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to isobutanol (engineered)";"Acetaldehyde biosynthesis I";"L-phenylalanine degradation III";"Naphthalene degradation";"Drug metabolism - cytochrome P450";"Chitin degradation to ethanol";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol I";"Noradrenaline and adrenaline degradation";"L-methionine degradation III";"Pyruvate fermentation to ethanol II";"Metabolism of xenobiotics by cytochrome P450";"Protein S-nitrosylation and denitrosylation";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol III";"Fatty acid degradation";"Formaldehyde oxidation II (glutathione-dependent)";"Chloroalkane and chloroalkene degradation";"Glycolysis / Gluconeogenesis";"alpha-Linolenic acid metabolism";"Ethanol oxidation";"Salidroside biosynthesis";"Tyrosine metabolism";"L-isoleucine degradation II";"Methane metabolism";"L-tryptophan degradation V (side chain pathway)";"3-methylbutanol biosynthesis (engineered)";"L-valine degradation II"
XP_050474804.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050478383.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050485476.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050481813.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"UCH proteinases";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin"
XP_050482441.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050488667.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050487015.1	12	MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II"
XP_050493122.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050481705.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050483410.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050470700.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050479998.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050479842.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050475129.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050478256.1	8	KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1	"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism"
XP_050476169.1	14	MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51	"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism"
XP_050476877.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050482954.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050477442.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050486168.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050483600.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955	"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation"
XP_050489675.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_050487481.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_050475895.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050482735.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050479084.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050472197.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_050484277.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050490527.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050475831.1	10	MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;Reactome: R-HSA-70370	"D-galactose detoxification";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism"
XP_050491740.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050471871.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050484750.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050492116.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_050494336.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050485455.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050483383.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6	"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism"
XP_050485681.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050473964.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050482041.1	3	MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141	"Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_050484907.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-1362300;Reactome: R-HSA-69231	"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1"
XP_050480117.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050486590.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_050483785.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_050470379.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482213.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050471808.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050491233.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis"
XP_050475748.1	7	Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-983231;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886	"HDMs demethylate histones";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_050481096.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050479353.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050486031.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050488573.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050492126.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_050481995.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_050474105.1	6	Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-913709;MetaCyc: PWY-7433	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation"
XP_050479386.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050487335.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050488868.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050478295.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050477540.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_050492389.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050478305.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050478100.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_050480587.1	8	KEGG: 00250+4.3.2.1;MetaCyc: PWY-4983;MetaCyc: PWY-5154;MetaCyc: PWY-4984;MetaCyc: PWY-5;KEGG: 00220+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-7400	"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Canavanine biosynthesis";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)"
XP_050478602.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050474797.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050485689.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids"
XP_050480103.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050473021.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050478055.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989	"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_050477095.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_050481974.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050481435.1	15	Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607	"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends"
XP_050480316.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050493512.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050476719.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-191859	"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly"
XP_050485663.1	11	Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_050477773.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050486805.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952	"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation"
XP_050491705.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_050478858.1	11	Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"IRF3-mediated induction of type I IFN";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_050483467.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050489823.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050489939.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050476847.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050484855.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_050489167.1	13	MetaCyc: PWY-6351;Reactome: R-HSA-2029485;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Role of phospholipids in phagocytosis";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050494371.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050475036.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050476241.1	4	Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-9615017	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_050481128.1	6	Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation"
XP_050475116.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_050482385.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050486394.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050471531.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050484879.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050478618.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050489701.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_050471507.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562	"Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria"
XP_050485152.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050493287.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050486512.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050470574.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050483311.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948	"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants"
XP_050494343.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050485690.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase"
XP_050491821.1	33	Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-141444	"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050471953.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation"
XP_050472775.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050481617.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_050477774.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050486927.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_050470207.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050480957.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050470421.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050495640.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050472000.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050471798.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050490570.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050483033.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050486972.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050483282.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050479092.1	7	KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050485770.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_050471004.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050471245.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity"
XP_050473826.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_050493950.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050492838.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050472284.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050474556.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050491007.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050484586.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_050483724.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050471226.1	11	Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253	"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock"
XP_050483133.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050477282.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_050478807.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493768.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050486393.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050482661.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050480255.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050479091.1	7	MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367	"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_050473343.1	8	MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_050487631.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050484228.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_050473795.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_050477256.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050475246.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex"
XP_050483415.1	18	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7226	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_050486247.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050480616.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050473338.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050478725.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050471095.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050473621.1	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_050481975.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Neutrophil degranulation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050482180.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050470251.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050490026.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050491552.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050483086.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress"
XP_050476487.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050470695.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050493099.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050469397.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482271.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050485659.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050485405.1	17	MetaCyc: PWY-5789;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Candicidin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis"
XP_050489493.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050487357.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050476915.1	12	MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4	"Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism"
XP_050487865.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050472147.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_050482214.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050493138.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050473214.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050489998.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_050483386.1	20	MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7338	"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_050473024.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050469914.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_050479149.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050485317.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism"
XP_050476140.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050470288.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050474660.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050493224.1	10	KEGG: 05165+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;Reactome: R-HSA-5357956;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"T cell receptor signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050491135.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050474876.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050485325.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7724	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_050494161.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_050495458.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050481178.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050471685.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_050491629.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050491839.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050488532.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050474344.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-72203	"mRNA Splicing - Major Pathway";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050477605.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719	"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF activation";"Ion transport by P-type ATPases";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors"
XP_050486766.1	8	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Recycling pathway of L1";"PI3K-Akt signaling pathway"
XP_050478377.1	8	Reactome: R-HSA-6787639;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-66;MetaCyc: PWY-5739;KEGG: 00520+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-5738	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis"
XP_050487417.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050470442.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin"
XP_050480805.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050491467.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_050485508.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050489277.1	7	Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1268020	"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"ATP biosynthesis";"Mitochondrial protein import"
XP_050492080.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050495565.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050493389.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050488521.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050471266.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050497108.1	5	KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-6906;MetaCyc: PWY-5514	"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_050478516.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA"
XP_050484948.1	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_050477561.1	12	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"TNF signaling";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation"
XP_050479119.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050472961.1	12	MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6613;KEGG: 00230+6.3.4.13;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9	"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate"
XP_050478173.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050492368.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050475061.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788	"Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling"
XP_050487700.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050472774.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050469585.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_050484900.1	5	MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_050470169.1	5	MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;Reactome: R-HSA-389661	"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Proline catabolism";"Glyoxylate metabolism and glycine degradation"
XP_050485634.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_050474985.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_050494189.1	13	MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates"
XP_050473060.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050472907.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050479138.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050476914.1	12	Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction";"Purine metabolism"
XP_050487375.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050473916.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050491481.1	24	Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"Gap junction assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"Kinesins";"Recycling pathway of L1";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
XP_050472808.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050477106.1	5	Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging"
XP_050472463.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050493513.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050492104.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050476167.1	13	MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7254	"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)"
XP_050480781.1	6	Reactome: R-HSA-8951664;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459	"Neddylation";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050479531.1	33	Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142	"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins"
XP_050480435.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050488648.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050480808.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050480118.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050471006.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050493745.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_050475464.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050477230.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling"
XP_050477928.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050478989.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050493429.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050481437.1	15	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)"
XP_050490728.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_050485400.1	17	KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2	"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism"
XP_050484243.1	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798	"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell"
XP_050493087.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050491922.1	19	Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-8876725;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-3214858;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Translation initiation complex formation";"Protein methylation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"RMTs methylate histone arginines";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050479157.1	5	Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3	"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_050493611.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050493353.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050472259.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050479486.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050470925.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050475248.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656	"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry"
XP_050486536.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_050493462.1	8	Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050472776.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050471752.1	29	Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation"
XP_050493458.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050480759.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050484252.1	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684	"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state"
XP_050489188.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_050472298.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444	"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050481425.1	15	Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence"
XP_050483429.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050475581.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_050476387.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050473927.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_050487168.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_050493231.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050479233.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_050480129.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050494327.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050479388.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050483428.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050474534.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050489069.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050478806.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050485680.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy"
XP_050479800.1	13	Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-139853	"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Ca2+ pathway";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels"
XP_050478131.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050486678.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050477459.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050493098.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050493694.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050471408.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_050469432.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050470173.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_050486392.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050491634.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_050483521.1	11	Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-202733;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253	"Syndecan interactions";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Cell surface interactions at the vascular wall";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_050493165.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050481109.1	6	KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_050490978.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050482750.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050482757.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_050470327.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050473235.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050484293.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050481215.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050487039.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050489055.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050484672.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_050481657.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050494383.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050474024.1	9	MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-5981	"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III"
XP_050471044.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050470977.1	13	Reactome: R-HSA-110320;Reactome: R-HSA-5362768;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-3371511;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-8876725;Reactome: R-HSA-5678895;Reactome: R-HSA-8866654;Reactome: R-HSA-382556;Reactome: R-HSA-5689896	"Translesion Synthesis by POLH";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Josephin domain DUBs";"HSF1 activation";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Protein methylation";"Defective CFTR causes cystic fibrosis";"E3 ubiquitin ligases ubiquitinate target proteins";"ABC-family proteins mediated transport";"Ovarian tumor domain proteases"
XP_050488397.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050489322.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050486638.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050488939.1	12	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-749476	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050487760.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050496363.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1989781	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"PPARA activates gene expression"
XP_050473105.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050480817.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050477662.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050487309.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050480484.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050494080.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050486980.1	13	Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3	"Metabolism of folate and pterines";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Folate transformations II (plants)";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate"
XP_050493604.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691	"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling"
XP_050495131.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV"
XP_050485298.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050484200.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_050484175.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050479488.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050478494.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050480314.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050474347.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050470054.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050478462.1	4	KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I";"Formation of xylulose-5-phosphate"
XP_050486587.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050481562.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050486554.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050486681.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050492137.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events"
XP_050476149.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050486404.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism"
XP_050482739.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050473159.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_050472028.1	9	Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-193648	"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK"
XP_050470170.1	5	Reactome: R-HSA-70688;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853	"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)"
XP_050486797.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050495916.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050486828.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050471434.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050481333.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050481410.1	8	Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_050475640.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050473723.1	5	MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050490568.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_050496985.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050492275.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_050486248.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050487041.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_050482209.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050475031.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050488955.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050472377.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050481226.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050483011.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050490010.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_050496625.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050492537.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050494089.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050475037.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050470172.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050473237.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050490036.1	17	Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_050483510.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050470414.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050482300.1	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050476110.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050486196.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050485118.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_050472143.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050474781.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050476885.1	29	KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-349425;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6803207;Reactome: R-HSA-5693568;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-6803204;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760	"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Regulation of TP53 Degradation";"Thermogenesis";"Stabilization of p53";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation"
XP_050474515.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050479147.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050479234.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050488661.1	4	MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_050484129.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050477926.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050482210.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050488714.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050474772.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050491263.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_050474890.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050472230.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050493381.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050488219.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_050482378.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050487082.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050474854.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050478109.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050479162.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050473942.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050489893.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050470758.1	17	Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-174048	"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_050488338.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_050472959.1	12	MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.9	"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"One carbon pool by folate"
XP_050473974.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050485234.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050477567.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050474835.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050477904.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_050479267.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050470767.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050471790.1	14	KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-3781;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7279;Reactome: R-HSA-611105;MetaCyc: PWY-6728	"Butanoate metabolism";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Methylaspartate cycle"
XP_050483038.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050481165.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050475915.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-110357	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1"
XP_050483926.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050493770.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050488925.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Translation initiation complex formation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_050472795.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050482822.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050489514.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050491985.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050488394.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050491460.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050492728.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050474168.1	7	KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-7158;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;MetaCyc: PWY-6134	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV"
XP_050490278.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050493235.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050486675.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050483701.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_050479357.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050482278.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_050489698.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050480653.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050470056.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_050493548.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050492876.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050475660.1	11	MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-5659;MetaCyc: PWY-882;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;MetaCyc: PWY-7586;MetaCyc: PWY-6992	"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Mannitol degradation II";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation"
XP_050486195.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050469495.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_050472238.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050486852.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050487611.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050481201.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050472702.1	14	Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Polymerase switching";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_050481186.1	3	Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117	"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis"
XP_050488321.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050482810.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050473215.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050477640.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_050470045.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050477610.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050472008.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050490894.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050483790.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8055;Reactome: R-HSA-1483166	"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA"
XP_050469464.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050492592.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050491915.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050470323.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050493672.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050473116.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_050484453.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050474635.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050476845.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050487639.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050476924.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050474212.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_050490972.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050479094.1	7	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050469893.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events"
XP_050487543.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050483970.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050493368.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050476739.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050476383.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity"
XP_050487726.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050488829.1	7	Reactome: R-HSA-1474151;MetaCyc: PWY-6614;Reactome: R-HSA-69205;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Folate biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations II (plants)"
XP_050484628.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050485049.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050475644.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050492776.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482014.1	6	MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5663	"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_050485929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050492536.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050471518.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050486609.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_050470711.1	12	MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118	"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Lupulone and humulone biosynthesis";"Methane metabolism";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Chitin degradation to ethanol"
XP_050497080.1	4	Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-446199	"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_050496210.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling"
XP_050474606.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050469529.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050487716.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050491739.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050485731.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA"
XP_050476510.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050471699.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-5826	"Glutathione metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis"
XP_050490823.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050483319.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955	"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050485157.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050491736.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050479137.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050478736.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050483987.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_050471611.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
XP_050492793.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_050494768.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050490015.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-176034	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins"
XP_050491470.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_050479247.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_050494056.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050490249.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050469565.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050479638.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050475465.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050483072.1	8	KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050489272.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_050478107.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050476381.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_050483922.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050490567.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_050472653.1	7	MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-8004;MetaCyc: PWY-5514;Reactome: R-HSA-71336	"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway"
XP_050473725.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_050489152.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_050479121.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050483782.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_050489477.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050493615.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050484898.1	5	Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6122	"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_050470554.1	4	KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030	"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis"
XP_050479983.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050483818.1	11	Reactome: R-HSA-2029485;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8053	"Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Sphingolipid metabolism";"Ether lipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II"
XP_050489866.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050496799.1	8	KEGG: 05165+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050478257.1	8	KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism"
XP_050480628.1	4	Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300	"DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA"
XP_050478891.1	8	MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate"
XP_050471248.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828	"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis"
XP_050482768.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050487001.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050480243.1	10	Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554	"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_050472470.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050482561.1	11	Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973	"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation"
XP_050487013.1	12	KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053	"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II"
XP_050481498.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050482162.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050470168.1	5	KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688	"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism"
XP_050479996.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050474893.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_050490227.1	52	Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76066;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-6781823	"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex"
XP_050473936.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_050485877.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050485393.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050473584.1	5	MetaCyc: PWY-5188;Reactome: R-HSA-189451;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_050478543.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050496407.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050471676.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050493602.1	3	Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2	"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway"
XP_050470372.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050475802.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050496896.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050493505.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050490056.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050479297.1	26	Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9619483	"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs"
XP_050487218.1	11	Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-193692	"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR"
XP_050469947.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050475201.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_050491597.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_050489386.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050485408.1	17	Reactome: R-HSA-163765;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744	"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Glyoxylate assimilation"
XP_050479256.1	8	Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050473807.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050475568.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_050497097.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050476245.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_050493095.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050491064.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Synthesis of PA";"Anandamide biosynthesis I";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism"
XP_050472249.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050470804.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050477695.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050484503.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_050478549.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_050495189.1	4	KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)"
XP_050472353.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050477467.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050477483.1	5	Reactome: R-HSA-4755579;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"N-Glycan biosynthesis"
XP_050470517.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_050479762.1	4	Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes"
XP_050492109.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050479899.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050481117.1	6	Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66	"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_050492657.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050481899.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050469409.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_050481806.1	6	KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;MetaCyc: PWY-6527	"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Stachyose degradation"
XP_050473873.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050492964.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050483097.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050470526.1	4	KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931	"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis"
XP_050486046.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050473949.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050477118.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050483180.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050481478.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391	"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"G alpha (q) signalling events";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling"
XP_050480081.1	9	MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664	"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_050479832.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050475054.1	4	Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_050480100.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050485694.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444	"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050475164.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050487783.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050496490.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_050483157.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050472006.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050492910.1	4	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050486965.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050474552.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-428540	"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions";"Activation of RAC1"
XP_050470284.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050480317.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050493137.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050471419.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050473738.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050489699.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050473037.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050479993.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050484983.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050470408.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050473976.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050496070.1	6	KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695	"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation"
XP_050476253.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050482275.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050475133.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050492551.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_050488171.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050480943.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050484323.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050484405.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050477879.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050485302.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050496387.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050470722.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050480944.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050488719.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050482146.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
XP_050490443.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050472800.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050487077.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050483930.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176407	"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050484396.1	12	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050494162.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_050474056.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050487764.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050473335.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050472122.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050485799.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050493778.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_050476357.1	5	Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3	"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes"
XP_050488160.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050484152.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050492770.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493645.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050477061.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_050474649.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050480286.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050469648.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050486376.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050494007.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050477355.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
XP_050494380.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050493469.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_050473585.1	12	Reactome: R-HSA-381183;MetaCyc: PWY-5189;Reactome: R-HSA-114608;MetaCyc: PWY-5188;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;KEGG: 00860+4.2.1.24;Reactome: R-HSA-381033;Reactome: R-HSA-6798695;Reactome: R-HSA-189451;Reactome: R-HSA-381070	"ATF6 (ATF6-alpha) activates chaperone genes";"Tetrapyrrole biosynthesis II (from glycine)";"Platelet degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Porphyrin and chlorophyll metabolism";"ATF6 (ATF6-alpha) activates chaperones";"Neutrophil degranulation";"Heme biosynthesis";"IRE1alpha activates chaperones"
XP_050479926.1	7	Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724	"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription"
XP_050493390.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050492629.1	6	Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722	"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex"
XP_050480831.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation"
XP_050471043.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050478378.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050494706.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_050496184.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050492334.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695	"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Neutrophil degranulation"
XP_050488970.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050489410.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050473311.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167290	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation"
XP_050480830.1	29	Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex"
XP_050492140.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050491127.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050486047.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050471838.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050476375.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation"
XP_050482608.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050470676.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050484472.1	6	MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism"
XP_050494492.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050491692.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050489472.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050493695.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050496142.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050481183.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050492950.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050481977.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050496135.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050483326.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948	"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants"
XP_050480285.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050483580.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050490123.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050488068.1	52	Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-6782210;Reactome: R-HSA-72165	"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway"
XP_050492523.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050470313.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050479669.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050489112.1	6	MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050484932.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050480502.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050471042.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050493026.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050487623.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050483806.1	10	Reactome: R-HSA-3000171;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-977225;Reactome: R-HSA-2453864	"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Neutrophil degranulation";"Purine metabolism";"Urate conversion to allantoin III";"Amyloid fiber formation";"Retinoid cycle disease events"
XP_050485737.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050494376.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050480630.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050479674.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_050474178.1	3	Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741	"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050489627.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050491601.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050473482.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050486339.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050482231.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050489151.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_050492580.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050496133.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050486713.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050478110.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_050496952.1	4	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050471691.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050494764.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050480075.1	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_050477385.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050473850.1	13	KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II"
XP_050470043.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050491702.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_050470567.1	7	Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5578749	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs"
XP_050489534.1	17	Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1221632;KEGG: 05163+2.7.11.1	"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Human papillomavirus infection";"Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"Meiotic synapsis";"Human cytomegalovirus infection"
XP_050496408.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050471304.1	8	Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050481307.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050487391.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_050494216.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_050487156.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050476165.1	13	KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2	"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes"
XP_050489276.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050473378.1	12	Reactome: R-HSA-5655302;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1	"Signaling by FGFR1 in disease";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Human cytomegalovirus infection";"Rho GTPase cycle";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection"
XP_050480127.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050492021.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_050477481.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050482815.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050487269.1	7	Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71064	"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism"
XP_050470285.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050475249.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656	"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry"
XP_050480884.1	12	KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476	"Human papillomavirus infection";"NRAGE signals death through JNK";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events"
XP_050494016.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050492480.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_050482013.1	6	MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6983	"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis"
XP_050482274.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050478567.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_050474889.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050480860.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050476466.1	10	Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.159;Reactome: R-HSA-983231;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6554;MetaCyc: PWY-6366;Reactome: R-HSA-1855204;MetaCyc: PWY-6362;MetaCyc: PWY-6365	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"
XP_050483329.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants"
XP_050487023.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050485548.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050485930.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050472574.1	7	MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_050485334.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050476890.1	6	KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050490563.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050476901.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_050494060.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_050492231.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_050475845.1	5	KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-71336;Reactome: R-HSA-6798695	"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"Neutrophil degranulation"
XP_050487562.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_050489031.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050480924.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050491829.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050492771.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050495043.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050469917.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050475060.1	6	Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16	"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050486547.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_050483729.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050471610.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_050472984.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050489903.1	4	KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801	"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion"
XP_050485935.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050486245.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050472709.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_050493245.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_050483717.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050494735.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050483221.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050491136.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050470337.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050470661.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050480498.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050489520.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050486337.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050473377.1	12	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"NRAGE signals death through JNK";"Human papillomavirus infection";"Rho GTPase cycle";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"Human immunodeficiency virus 1 infection"
XP_050477603.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-111932	"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Long-term potentiation";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB"
XP_050473971.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050482097.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_050488190.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4641262	"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"PCP/CE pathway";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_050473620.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-174084	"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_050486814.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205	"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Purine metabolism"
XP_050484865.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_050492253.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050491682.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050474091.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050493328.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050480927.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050479555.1	9	Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends"
XP_050493102.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050492331.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050471094.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050471364.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356	"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_050475954.1	11	Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050482919.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050471259.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050474901.1	9	MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Phosphatidylinositol signaling system"
XP_050483315.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_050481555.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050494015.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050471985.1	14	MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-3781;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1	"Methylaspartate cycle";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism"
XP_050482006.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050472187.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050477795.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6804756	"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation"
XP_050493085.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050477777.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_050491079.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050478847.1	6	KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52	"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_050488815.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050492832.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050473676.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050494247.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050482548.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050472556.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_050474736.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050489079.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050470720.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_050482759.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050487641.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050477452.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5689877	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Josephin domain DUBs"
XP_050493468.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_050487621.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050470247.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050487252.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_050488716.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050483047.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_050493700.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050469465.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050470243.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050485633.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_050474224.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050481923.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_050494335.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050483227.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_050488169.1	10	Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9022538	"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA"
XP_050482730.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050475042.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050496812.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050489043.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_050471309.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_050473581.1	7	Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381042;Reactome: R-HSA-381183	"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_050473328.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8053	"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II"
XP_050477117.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050493518.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050495567.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_050475673.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050476188.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050481618.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_050494188.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050487470.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050484921.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050490655.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050488887.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050489928.1	19	Reactome: R-HSA-6798695;Reactome: R-HSA-75105;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5	"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Propanoate metabolism"
XP_050478980.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050481717.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050480289.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050479484.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050470276.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050491680.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_050478752.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050488168.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050489489.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050493543.1	14	MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634	"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport"
XP_050482164.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050470569.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746	"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein"
XP_050478385.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050494238.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050472089.1	4	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_050481933.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_050477108.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108	"Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050492571.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_050474745.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050476700.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050494953.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050479380.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050480806.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050477294.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050485992.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_050469391.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050473802.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050491458.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050480715.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050470525.1	7	KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7841	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis"
XP_050472658.1	17	Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_050474837.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050473436.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol"
XP_050485495.1	8	Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;MetaCyc: PWY-7221	"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis"
XP_050490973.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050491785.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050487688.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_050478496.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050475182.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050469649.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050472088.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938	"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)"
XP_050493020.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050488944.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050481163.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050482338.1	7	Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596	"Neutrophil degranulation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I"
XP_050492388.1	4	Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852	"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Macroautophagy"
XP_050490746.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_050481302.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050470664.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050486637.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050488210.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_050483474.1	18	KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;MetaCyc: PWY-5913	"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"(R)-cysteate degradation";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)"
XP_050497029.1	14	MetaCyc: PWY-5076;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5104;MetaCyc: PWY-5057;MetaCyc: PWY-7767	"L-leucine degradation III";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)"
XP_050487991.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050482280.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050486691.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_050483849.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050493257.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050470915.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)"
XP_050482485.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050487323.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_050488107.1	3	Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_050491896.1	24	Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-416482	"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events"
XP_050488641.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_050489450.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050475085.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050482952.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050480948.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050473965.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050472002.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050478203.1	11	Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170670	"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway"
XP_050482282.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050490931.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_050486532.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050481234.1	33	Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-141444	"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050487972.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050478376.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050475378.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050478293.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050495183.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050479276.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050472254.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050496915.1	3	Reactome: R-HSA-420029;Reactome: R-HSA-4608870;Reactome: R-HSA-2173791	"Tight junction interactions";"Asymmetric localization of PCP proteins";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_050490128.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050489929.1	19	Reactome: R-HSA-6798695;MetaCyc: PWY-5913;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5537;MetaCyc: PWY-5172;Reactome: R-HSA-163765;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5	"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Propanoate metabolism";"C5-Branched dibasic acid metabolism"
XP_050488422.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050469847.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050472708.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_050480936.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050478553.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825	"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_050484468.1	6	KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6364	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_050491639.1	7	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14	"Purine metabolism";"Thiamine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes"
XP_050481491.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050494054.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050482632.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050485064.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050476967.1	14	MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4	"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Arachidonic acid metabolism"
XP_050480102.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050475013.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050471438.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050483568.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050492490.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_050490089.1	4	Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26	"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate"
XP_050493773.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_050472374.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050484940.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050484429.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050481534.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050478545.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_050469976.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442	"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs"
XP_050489017.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050484125.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050487578.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"O-linked glycosylation"
XP_050490569.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_050470248.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050477220.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050475555.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050493710.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050481235.1	10	KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
XP_050482225.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050485687.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_050481343.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050492968.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050489658.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296	"HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome"
XP_050472210.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787	"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'off' state"
XP_050470859.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050476784.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050472888.1	6	KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6749;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation"
XP_050480949.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050496925.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050477272.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050472005.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050469706.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050481801.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050476585.1	10	MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861	"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Galactose metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050482281.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050474095.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050469624.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493786.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050488943.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050477717.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050482787.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050484510.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050488189.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262	"RHO GTPases Activate Formins";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_050496909.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050486052.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050483935.1	5	MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;MetaCyc: PWY-7919;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050477925.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050488844.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050472251.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050489014.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050487644.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050489291.1	20	Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5693607	"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Processing of DNA double-strand break ends"
XP_050480841.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-212436	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway"
XP_050470663.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050482294.1	2	MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050472521.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_050478044.1	8	Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483	"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs"
XP_050470828.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050474314.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050477286.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_050470071.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_050471954.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050481600.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_050477038.1	7	MetaCyc: PWY-6840;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2	"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism"
XP_050481170.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050494087.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050474219.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-3238698	"Neutrophil degranulation";"WNT ligand biogenesis and trafficking"
XP_050496360.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472	"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050483432.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_050476582.1	10	MetaCyc: PWY-7385;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11	"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Methane metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis"
XP_050489293.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050478708.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_050477619.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802955	"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050469563.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_050475084.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050492946.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes"
XP_050477923.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape"
XP_050471683.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex"
XP_050492757.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050486624.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_050475306.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_050475504.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_050483314.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_050471525.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050491008.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050492363.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050480925.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050475538.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050482027.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050492588.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050477779.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050477994.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050484697.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050494088.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050482736.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050469902.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050481798.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050489474.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050473310.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167158	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex"
XP_050481656.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050477037.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050472471.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050476228.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050495835.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876	"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050477134.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050496837.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050469943.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050480945.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050482475.1	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050475528.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050471081.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050492462.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050474526.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050479080.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism"
XP_050491648.1	7	MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism"
XP_050469458.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050474007.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050486384.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050478476.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050470689.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408	"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism"
XP_050476798.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_050483860.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050485331.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)"
XP_050493001.1	12	KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932	"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction"
XP_050481905.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_050474554.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Activation of RAC1";"Nephrin family interactions";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_050477781.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_050469924.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760	"RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation"
XP_050470951.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_050481653.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050473622.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_050489807.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_050494051.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_050488670.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050478550.1	6	KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_050487442.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050488824.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050494206.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_050475044.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050474016.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_050480527.1	3	Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320	"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH"
XP_050485281.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_050489619.1	7	KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III"
XP_050474805.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050470301.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050490820.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050484680.1	6	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050472520.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_050495346.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631	"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility"
XP_050476636.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050478822.1	14	KEGG: 04070+3.1.4.11;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-1855204;Reactome: R-HSA-434316;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-112043;MetaCyc: PWY-6367;Reactome: R-HSA-418217;MetaCyc: PWY-6351	"Phosphatidylinositol signaling system";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"Synthesis of IP3 and IP4 in the cytosol";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Acetylcholine regulates insulin secretion";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"G beta:gamma signalling through PLC beta";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_050486466.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_050471608.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_050484766.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050480814.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050482968.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050492712.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050491959.1	16	Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050470317.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050479942.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050491986.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050469746.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050483012.1	5	MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050474916.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050482010.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-1433559	"Neddylation";"Regulation of KIT signaling"
XP_050489741.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050474747.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050486960.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050474030.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050479853.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050472742.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050487763.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050487599.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050484625.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050485014.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050480123.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050471172.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050486607.1	12	Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152	"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_050489012.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050480758.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050479605.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050477287.1	11	Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-170670	"Hedgehog 'off' state";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway"
XP_050473107.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050488602.1	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;MetaCyc: PWY-7250;Reactome: R-HSA-947581	"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050473926.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050475171.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050469952.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050484980.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050472137.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_050473940.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050477174.1	5	Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-9627069	"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity"
XP_050479886.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050471510.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_050476562.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050487233.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050470907.1	13	MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-7736	"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis"
XP_050474012.1	5	Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050490653.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050478607.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922	"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_050489908.1	4	KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603	"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine"
XP_050481607.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Ub-specific processing proteases";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_050475039.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050478809.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050470912.1	5	KEGG: 00230+3.6.1.6;MetaCyc: PWY-7210;MetaCyc: PWY-7185;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6	"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Pyrimidine metabolism"
XP_050478285.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050477655.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050487689.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050483805.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050477927.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050490817.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050477137.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050496395.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050491710.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050489340.1	13	Reactome: R-HSA-437239;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-416993	"Recycling pathway of L1";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"LDL clearance";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors"
XP_050477929.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050483441.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050477591.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324	"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_050479139.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050490607.1	5	Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994	"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050469919.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_050480733.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050472114.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050492716.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050475192.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation"
XP_050476916.1	12	KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550	"Purine metabolism";"Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"
XP_050481622.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_050477086.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050477115.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050490152.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050483494.1	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7198	"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_050483113.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050489033.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050488717.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050476216.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050485615.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601	"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_050497024.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_050473966.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050483549.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050488271.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050485744.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050480108.1	5	MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)"
XP_050489295.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050482301.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050489774.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050473490.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050483808.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050476102.1	16	MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-2046105;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6433;Reactome: R-HSA-2046106;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Linoleic acid (LA) metabolism";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"alpha-linolenic acid (ALA) metabolism";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation"
XP_050483085.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050493605.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050486631.1	17	Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-450302;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-4086398;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-2871837	"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"Ca2+ pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation"
XP_050474288.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050473724.1	11	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050481517.1	4	Reactome: R-HSA-901032;KEGG: 00513+3.2.1.113;KEGG: 00510+3.2.1.113;MetaCyc: PWY-7919	"ER Quality Control Compartment (ERQC)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)"
XP_050484463.1	7	Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67	"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism"
XP_050480730.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050491231.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214	"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_050473238.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050491307.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050489488.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050473952.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050489321.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050492718.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050471513.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050492582.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050470058.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_050477229.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"TP53 Regulates Metabolic Genes"
XP_050494767.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050490390.1	6	KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22	"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions"
XP_050486906.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050481467.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050485706.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation"
XP_050496961.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050477142.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_050473054.1	18	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_050478756.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050472048.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050487602.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050491542.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050477739.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050482161.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050493127.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050482208.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050488329.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050472193.1	12	Reactome: R-HSA-71240;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13	"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism"
XP_050487189.1	34	Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180746	"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Nuclear import of Rev protein"
XP_050478734.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_050480500.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050476834.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_050497037.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050489892.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050481958.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050470239.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050491732.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050477616.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-111932	"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB"
XP_050487334.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050494179.1	13	MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_050478805.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050480912.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050480960.1	6	MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6608;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606	"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation II"
XP_050476713.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050481450.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_050477588.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244	"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation"
XP_050487642.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050488523.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050473163.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-6794361	"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Neurexins and neuroligins"
XP_050490221.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050486314.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050496801.1	11	Reactome: R-HSA-5668599;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"RHO GTPases Activate NADPH Oxidases";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_050472547.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050472104.1	58	Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-5689901;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176	"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Metalloprotease DUBs";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_050470752.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050470281.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050492847.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050493942.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_050484508.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050495647.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050492010.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050487520.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537	"HDACs deacetylate histones";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_050482740.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050485481.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050484398.1	12	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050475886.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050493457.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050486030.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050483321.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948	"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants"
XP_050481901.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050478589.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050480328.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_050485824.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050490409.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050492319.1	12	MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801	"Sucrose biosynthesis II";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Stachyose degradation";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)"
XP_050473218.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050494048.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_050491855.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050491973.1	5	KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95;Reactome: R-HSA-977347;KEGG: 00680+1.1.1.95;MetaCyc: PWY-8010	"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
XP_050488724.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050474997.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_050482877.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050477942.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050492250.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050493470.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_050471255.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050485873.1	14	Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1474228;Reactome: R-HSA-3928665	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of the extracellular matrix";"EPH-ephrin mediated repulsion of cells"
XP_050470236.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3371453	"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response"
XP_050491638.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050486054.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050488524.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050494755.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050470857.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050474116.1	9	MetaCyc: PWY-7112;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes"
XP_050490296.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_050473677.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050481814.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_050474678.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-3108214	"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_050485808.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050494052.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_050475741.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050473104.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050485299.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050477546.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050478874.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050488302.1	13	KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;Reactome: R-HSA-156590	"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation"
XP_050475959.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050492870.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_050491709.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483	"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)"
XP_050471237.1	18	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation"
XP_050487456.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_050497027.1	14	MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5101;MetaCyc: PWY-5057;MetaCyc: PWY-7767;Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42	"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis II";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)";"Branched-chain amino acid catabolism";"L-leucine degradation III";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis"
XP_050492314.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050470340.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050493801.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_050477315.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050477029.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050479966.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050470558.1	20	Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69473	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint"
XP_050487982.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050494053.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050476215.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050477604.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-936837	"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases"
XP_050474422.1	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2	"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism"
XP_050493871.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_050477806.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050482004.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_050471505.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050478600.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050485611.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050471258.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050482341.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050483656.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050489022.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050469856.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050479224.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050470598.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050491321.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050486402.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2"
XP_050473996.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050475586.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_050487808.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_050483728.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050474009.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_050476613.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050474900.1	9	MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Phosphatidylinositol signaling system"
XP_050482174.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050477623.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-111932	"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation";"RAF activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB"
XP_050491413.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_050472579.1	7	MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_050469410.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_050480834.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_050479911.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_050484202.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_050493103.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050472814.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_050470619.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050495840.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_050480739.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050486278.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050489516.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050492575.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050483908.1	22	MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-6958;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050481404.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050486552.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050473038.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050481561.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050469747.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050469582.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_050474454.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_050482376.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050485765.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_050472817.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_050494219.1	7	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050492966.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050473962.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050479106.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_050476055.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050476481.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_050471519.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050487978.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050494194.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050480241.1	10	KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661	"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_050479116.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050478861.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_050470732.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050471243.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828	"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis"
XP_050489010.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050487255.1	29	Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-912446	"Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Meiotic recombination"
XP_050472102.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050471895.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050496631.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050471807.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050475992.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050484450.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050493629.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050488877.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050491239.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_050494226.1	7	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050476231.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050474220.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050484067.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050487750.1	52	Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-76071	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050479915.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050484981.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050483990.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_050486971.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050489124.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050485477.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050469598.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050488209.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_050481722.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050470669.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050485683.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion"
XP_050480359.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050474457.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243	"Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050496794.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050487324.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_050486287.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050471562.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050482650.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050480722.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1"
XP_050487171.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050492326.1	12	MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9	"Sucrose biosynthesis II";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Stachyose degradation";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism"
XP_050477612.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952	"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions"
XP_050470217.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050489283.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050474897.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050485658.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050477471.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050474284.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_050482953.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050489858.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050484489.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050473777.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050491827.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_050487199.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050497052.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050493118.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050483290.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050488097.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_050476917.1	12	KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25	"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism"
XP_050477652.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_050492700.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-6708;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_050471041.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050476379.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_050482814.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050474346.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-9610379;Reactome: R-HSA-72203;Reactome: R-HSA-4570464	"mRNA Splicing - Major Pathway";"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins"
XP_050482414.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050486918.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050473992.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050475158.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050494005.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050475075.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050473919.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050471641.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050493425.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050479940.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050482284.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050488218.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050489468.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050488328.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050484534.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050490577.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050483527.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050484190.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050491577.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050477036.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050495038.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050488213.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_050492731.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050484311.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050484761.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_050470954.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050491984.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050470504.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050472822.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050488727.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050492442.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050469567.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_050474555.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050472255.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050483715.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050478464.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050469581.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_050491626.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050484507.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_050489394.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050482560.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050473928.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_050477895.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050472803.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050484639.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050492753.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050485704.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation"
XP_050473678.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050483356.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-6811558	"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_050484681.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050494993.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050482564.1	11	Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-428890	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling"
XP_050469670.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_050480290.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050484588.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_050486846.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050480503.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050477805.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050491259.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-211981	"Endogenous sterols";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"Xenobiotics"
XP_050493258.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050479676.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050478558.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_050488938.1	12	Reactome: R-HSA-1834949;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050485168.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050479470.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050487826.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050471996.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050471064.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050477860.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050489187.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050484404.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050488355.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Polymerase switching";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK"
XP_050478716.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050489333.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation"
XP_050494249.1	11	Reactome: R-HSA-391160;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-909733;Reactome: R-HSA-877312;Reactome: R-HSA-912694;Reactome: R-HSA-9008059;Reactome: R-HSA-210990	"Signal regulatory protein family interactions";"Platelet sensitization by LDL";"PD-1 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Interferon alpha/beta signaling";"Regulation of IFNG signaling";"Regulation of IFNA signaling";"Interleukin-37 signaling";"PECAM1 interactions"
XP_050480438.1	24	KEGG: 04151+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218921;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"Relaxin signaling pathway";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Thermogenesis";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"Activation of AKT2";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"RSK activation";"VEGFR2 mediated cell proliferation";"Human cytomegalovirus infection"
XP_050469863.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050486966.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050483497.1	13	KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_050494449.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_050469470.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050494293.1	23	Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-418594	"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G-protein activation";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events"
XP_050493398.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050489458.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling"
XP_050496613.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050472850.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050476759.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050485034.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_050492577.1	11	Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-69166	"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate"
XP_050489137.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377	"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of SUMOylation proteins"
XP_050485029.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050485518.1	13	Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Extracellular matrix organization";"Collagen degradation"
XP_050485565.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050487637.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050493665.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050486249.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050491211.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358751	"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"RAF activation";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated"
XP_050481558.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_050491448.1	4	MetaCyc: PWY-5874;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483	"Heme degradation I";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation"
XP_050486274.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050482574.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050470375.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050492281.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_050476378.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050471398.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050485939.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050484448.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050493674.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050496156.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_050488423.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050480968.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050487779.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050485232.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050471015.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_050481172.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050481554.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_050470075.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050481216.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050473158.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_050470303.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050493739.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_050478277.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050472713.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_050490891.1	17	MetaCyc: PWY-7205;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7184	"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_050484988.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050477068.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050489284.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_050470845.1	9	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050496966.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050493790.1	13	Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825	"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis"
XP_050489296.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050489052.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837	"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation"
XP_050478241.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050490502.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050489138.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168271	"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_050469871.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050471642.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050491869.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050488721.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050491495.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-8939243	"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050489289.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050493340.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050493431.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050484877.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_050495609.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050476372.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_050471692.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050471415.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050493375.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050475111.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050473894.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_050487293.1	13	Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757	"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation"
XP_050479667.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050469814.1	20	Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920	"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"Macroautophagy";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Thermogenesis";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"Human cytomegalovirus infection";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Human papillomavirus infection";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability"
XP_050477868.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050469393.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482171.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050488324.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050477617.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952	"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions"
XP_050492325.1	12	MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9	"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Glycerolipid metabolism";"Pentose and glucuronate interconversions"
XP_050486251.1	11	KEGG: 04151+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection"
XP_050487983.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050484828.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050480040.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050469461.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050477449.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050492896.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050497031.1	14	MetaCyc: PWY-5104;MetaCyc: PWY-5101;MetaCyc: PWY-7767;MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5103	"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis II";"L-leucine degradation IV (Stickland reaction)";"L-valine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine degradation II";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Branched-chain amino acid catabolism";"L-leucine degradation III";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis III"
XP_050472240.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050472987.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050473776.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050485580.1	52	Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-76071;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-73762;Reactome: R-HSA-203927	"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis"
XP_050482408.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050481802.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050486858.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050478233.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050483869.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_050484470.1	6	KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_050475107.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_050488768.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050496160.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050484310.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050493788.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050482805.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050476377.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_050489812.1	18	MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4	"Plasmalogen degradation";"Synthesis of PA";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Ether lipid metabolism"
XP_050483496.1	13	MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1	"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Glutathione metabolism"
XP_050484637.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050477167.1	22	MetaCyc: PWY-7606;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_050489473.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050471361.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer"
XP_050480515.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050483783.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8055;Reactome: R-HSA-1483166	"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA"
XP_050475742.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050482177.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050476580.1	10	KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050475655.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050477660.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050484348.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_050476948.1	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050483354.1	5	Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558	"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_050471236.1	18	Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-166208;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"Translation initiation complex formation";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_050493519.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050481468.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050494564.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050469395.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050480963.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_050494070.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050482786.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050486711.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050489184.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_050480811.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050470216.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050479909.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050472083.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
XP_050480074.1	4	MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_050475066.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050476163.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_050472771.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050469579.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_050469972.1	11	MetaCyc: PWY-5913;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-6728	"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Methylaspartate cycle"
XP_050493218.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050487950.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_050494069.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050475529.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050483732.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050480734.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050476064.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050486588.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050494774.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050496099.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050478235.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050477884.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_050491472.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050470580.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050492387.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695	"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation"
XP_050492871.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_050477307.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050469526.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050487706.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050484244.1	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684	"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state"
XP_050495811.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_050489113.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_050482633.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050486617.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_050490403.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050472976.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050487807.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_050479071.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050488066.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050491953.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050482018.1	6	MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6983	"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis"
XP_050483355.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001	"PIP3 activates AKT signaling";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade"
XP_050470096.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_050478753.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050488865.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050494011.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050470436.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050482609.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050470955.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050481459.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_050469940.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050494057.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050491185.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050481006.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050494392.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050477273.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050492139.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050489078.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050487126.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050471417.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050482057.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050469938.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050470675.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050486354.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050469463.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050491965.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050469701.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050489914.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050483804.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050488752.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_050486350.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_050481038.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050474785.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_050475515.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050479115.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050487624.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050484713.1	26	Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332	"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Kinesins";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin"
XP_050484873.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050489004.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_050492907.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050486561.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050492773.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050481983.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050469678.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050484162.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050480248.1	10	MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050486961.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050484196.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050488559.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050469425.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050474983.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050480699.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050492054.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050481026.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"mTOR signalling"
XP_050482269.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050478454.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050478282.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050474225.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050496846.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050471612.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_050489579.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-68962	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Polymerase switching";"DNA replication initiation";"Activation of the pre-replicative complex"
XP_050474746.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050476570.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050470888.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050471410.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050469597.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050491457.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050484497.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050489041.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050481979.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050478873.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050483725.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050477192.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_050487867.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050482471.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_050484482.1	14	MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409	"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_050472787.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050473270.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050493598.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050488494.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050486172.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050473921.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050473227.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050472705.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314	"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Polymerase switching";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050475063.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050479045.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050480242.1	10	MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism"
XP_050489806.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_050472189.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050474348.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-72203	"mRNA Splicing - Major Pathway";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050480249.1	10	MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism"
XP_050482874.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050485193.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"Degradation of the extracellular matrix";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
XP_050497112.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_050496830.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_050484772.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050471068.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050489335.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050472880.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050484464.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism"
XP_050487139.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_050478228.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050472848.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050484827.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050476949.1	4	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050484148.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050476846.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050482782.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050497107.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6906	"Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation"
XP_050472960.1	12	KEGG: 00230+6.3.3.1;KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6121;KEGG: 00230+2.1.2.2;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6277;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6122	"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Biotin transport and metabolism";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_050474404.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050482176.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050484509.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050485530.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050497044.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050485654.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050494055.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_050491543.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050477440.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050471221.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050482800.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050478086.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis"
XP_050485381.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050479496.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism";"Circadian Clock";"Th1 and Th2 cell differentiation"
XP_050480895.1	12	Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885	"Rho GTPase cycle";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"DCC mediated attractive signaling"
XP_050491721.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050485822.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050472206.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050476019.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050492765.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050490307.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_050488346.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050470057.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_050496021.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050494217.1	7	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_050483928.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-179409	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A"
XP_050483036.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050485418.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050474221.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-3238698	"Neutrophil degranulation";"WNT ligand biogenesis and trafficking"
XP_050480357.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050469555.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050496946.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050497039.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050481314.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-165054	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA"
XP_050478284.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050494775.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050493848.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050480632.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050492138.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050479843.1	11	KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007	"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events"
XP_050485554.1	18	Reactome: R-HSA-5362517;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-389661;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00280+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-6783984;MetaCyc: PWY-5084;KEGG: 00020+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00010+1.8.1.4	"Signaling by Retinoic Acid";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Valine, leucine and isoleucine degradation";"Glycine, serine and threonine metabolism";"Branched-chain amino acid catabolism";"Glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Lysine degradation";"Propanoate metabolism";"Glycolysis / Gluconeogenesis"
XP_050491504.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_050471039.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050485696.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444	"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050493078.1	10	Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554	"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050478470.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_050471249.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050485547.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050491704.1	4	MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662	"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism"
XP_050478461.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050475167.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050469945.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050472643.1	5	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050477642.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050496953.1	4	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050482476.1	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-6796648	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050492961.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050471070.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_050480858.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050475052.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132	"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_050473582.1	5	Reactome: R-HSA-189451;Reactome: R-HSA-6798695;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24	"Heme biosynthesis";"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_050490219.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050479131.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050476830.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050470581.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050477487.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050488167.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050492046.1	6	MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6118	"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle"
XP_050493146.1	6	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64;Reactome: R-HSA-1660517;MetaCyc: PWY-6580;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.64	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_050489492.1	6	KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3	"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism"
XP_050476955.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050475101.1	11	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050481174.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050479761.1	4	Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes"
XP_050484748.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050481160.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050473830.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade"
XP_050491396.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050490309.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050478147.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_050481244.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_050489765.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050496358.1	12	MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)"
XP_050496899.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_050470148.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_050472941.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050480961.1	6	MetaCyc: PWY-6606;MetaCyc: PWY-7442;MetaCyc: PWY-6608;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497	"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)"
XP_050489166.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050478002.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050488579.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050483565.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_050470666.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050484283.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050470815.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852	"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy"
XP_050470035.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050478563.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050479085.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050470903.1	13	MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-7102;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7736;MetaCyc: PWY-7659	"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis"
XP_050488533.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050493992.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050475303.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050476860.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050489901.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_050475549.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050483965.1	4	KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism"
XP_050480964.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050482818.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050484237.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050481317.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_050486398.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_050489652.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_050477905.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168271	"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_050484716.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050473617.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050483845.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050488814.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_050491509.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"Interleukin-7 signaling"
XP_050483526.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050483285.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050490069.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050496353.1	12	MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms"
XP_050493025.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050484662.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050478717.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050471206.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes"
XP_050473487.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050486592.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050476179.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050494574.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050485026.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050474735.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050494235.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_050471313.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_050489622.1	5	KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III"
XP_050493606.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_050479677.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050469601.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050485155.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050492051.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050490798.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050477441.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050487976.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050490702.1	4	Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_050483081.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68689	"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex"
XP_050482245.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050475441.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050470321.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050481601.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_050482600.1	5	Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221	"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"RAF activation";"Negative regulation of MAPK pathway"
XP_050488371.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050469604.1	33	Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-141444	"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050485941.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050471864.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_050470110.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050486907.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050481673.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050485802.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050477031.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050479968.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050488317.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050479938.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050488493.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050487829.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050493777.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_050487692.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050481344.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050491835.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050492951.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_050489517.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050482664.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_050469536.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050477638.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050473786.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_050487441.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050474427.1	7	Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2	"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism"
XP_050479833.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050493592.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050472486.1	4	KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621	"Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism"
XP_050493237.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050490470.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050485042.1	3	Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067	"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_050473023.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050481800.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050487443.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050481620.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_050496279.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_050485015.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050483147.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050480327.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050489651.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_050491693.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050479109.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050470524.1	7	MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-5129;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7841	"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis"
XP_050473155.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050485754.1	7	MetaCyc: PWY-3385;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7818	"Choline biosynthesis I";"Synthesis of PC";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_050490461.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050494294.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050483868.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_050485102.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050488650.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050489738.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_050496352.1	12	Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385	"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)"
XP_050492597.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050474500.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050480765.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050474553.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097	"Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway"
XP_050486768.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_050493792.1	13	Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665	"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_050493537.1	14	MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5	"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism"
XP_050474981.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050475213.1	9	Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"mTOR signaling pathway"
XP_050488580.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050481619.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_050473216.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050473192.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050485098.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050470319.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050483087.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68827	"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_050487282.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050487182.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050471827.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050490893.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050478958.1	5	KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)"
XP_050479596.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050486456.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050491001.1	15	Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402	"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex"
XP_050480486.1	5	MetaCyc: PWY-7782;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241	"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Peroxisomal protein import"
XP_050490977.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050492504.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050489697.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050476535.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_050489469.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050489632.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050483859.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050482205.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050471802.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050472231.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050470791.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050484445.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050481553.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_050485344.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050470477.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-3214858	"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"RORA activates gene expression";"RMTs methylate histone arginines"
XP_050485475.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050473960.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527	"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation"
XP_050482937.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050493143.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050486284.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050487017.1	12	KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7783	"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation"
XP_050471945.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050475525.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050491114.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050487192.1	8	KEGG: 00790+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5049;Reactome: R-HSA-209905;MetaCyc: PWY-6133;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;MetaCyc: PWY-3581	"Folate biosynthesis";"Tyrosine metabolism";"Rosmarinic acid biosynthesis II";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis II";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis I"
XP_050488788.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050487960.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_050483292.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050483165.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-1442490	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Collagen degradation"
XP_050470415.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050490501.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050469864.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050482519.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050490277.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_050491747.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_050470712.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050490875.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_050473194.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050485607.1	14	MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725	"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050474086.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050493651.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050482791.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050472495.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050477235.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050484882.1	5	KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20	"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes"
XP_050485494.1	12	Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-451308;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;MetaCyc: PWY-7221	"Trafficking of AMPA receptors";"Long-term potentiation";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis"
XP_050486633.1	14	MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51	"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism"
XP_050483295.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050474017.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_050469459.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050485489.1	12	Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;MetaCyc: PWY-7221	"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_050495069.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050473685.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050491640.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050488278.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050475377.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050472865.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050484229.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050482590.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168	"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)"
XP_050494174.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_050486290.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050491962.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569	"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_050470449.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_050492055.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-8939236;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production"
XP_050480388.1	7	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485	"Synthesis of PA";"Synthesis of PG";"Ether lipid metabolism";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis"
XP_050483726.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050487818.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050491506.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines"
XP_050485755.1	7	MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385	"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Choline biosynthesis I"
XP_050492511.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050481508.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050485287.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050489476.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050492492.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050490469.1	8	KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050477568.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050491866.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050489147.1	16	KEGG: 00640+6.2.1.4;MetaCyc: PWY-5537;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690	"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)"
XP_050491003.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050480920.1	7	KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation"
XP_050496921.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050485472.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050492359.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050476158.1	5	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050478692.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174154	"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin"
XP_050481530.1	4	Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-156581	"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"Methylation"
XP_050478382.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050490279.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050487780.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050478857.1	11	KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571	"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"Thermogenesis";"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)"
XP_050478204.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050480779.1	17	Reactome: R-HSA-69091;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-69166	"Polymerase switching";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate"
XP_050474170.1	7	KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1	"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylketonuria";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_050487836.1	14	KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-7124	"Glycolysis / Gluconeogenesis";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)"
XP_050491399.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050491895.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_050470933.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050476738.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050487526.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050486082.1	5	MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341	"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)"
XP_050476907.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050486962.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050487325.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_050482999.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050471213.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050486399.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_050483575.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050484490.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050476900.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_050489497.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050469946.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050487567.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050469694.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050470478.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340	"Circadian Clock";"RORA activates gene expression";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation"
XP_050479358.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050496898.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050473764.1	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050482594.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation"
XP_050475956.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050477639.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050485641.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_050489451.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_050482421.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050480101.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050479337.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-1234158	"Activation of the TFAP2 (AP-2) family of transcription factors";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RORA activates gene expression";"Circadian Clock";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"HATs acetylate histones";"PPARA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_050492279.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_050473351.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050485323.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050491309.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050473961.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050497026.1	14	KEGG: 00280+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-7767;MetaCyc: PWY-5057;MetaCyc: PWY-5104;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5103;Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00966+2.6.1.42	"Valine, leucine and isoleucine degradation";"L-isoleucine degradation II";"L-leucine degradation IV (Stickland reaction)";"L-valine degradation II";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis III";"Branched-chain amino acid catabolism";"L-leucine degradation III";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"Glucosinolate biosynthesis"
XP_050474331.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050487501.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050483103.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050490617.1	5	Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693	"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism"
XP_050481316.1	14	Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050474731.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050492343.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050496823.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050477227.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling"
XP_050495268.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050475055.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050491932.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050487471.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050485411.1	17	Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-6679;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-196780	"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Biotin transport and metabolism"
XP_050486273.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050476488.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050494346.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050472235.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050471567.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050488928.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050470698.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050494761.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050476614.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050491954.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050479158.1	5	KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Cysteine and methionine metabolism";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_050487169.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050476482.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_050478463.1	4	KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;Reactome: R-HSA-5661270	"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Formation of xylulose-5-phosphate"
XP_050481658.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050496186.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050481041.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050476365.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_050495829.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050486431.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050476848.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050491048.1	7	MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Phytate degradation I";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_050471957.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050486011.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050478289.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050483034.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050489950.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050491964.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050487214.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050474350.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-72203;Reactome: R-HSA-9610379	"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events"
XP_050472919.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-9603505;Reactome: R-HSA-167290;Reactome: R-HSA-167158	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"NTRK3 as a dependence receptor";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex"
XP_050493238.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050491969.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050473806.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050475848.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_050486738.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050482115.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050485684.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase"
XP_050474742.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050469545.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050493371.1	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050474999.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_050486285.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050490067.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050473775.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050471774.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050471694.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7559	"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway"
XP_050482448.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050493990.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050477136.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050491744.1	4	Reactome: R-HSA-3359463;Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-196741	"Defective CUBN causes hereditary megaloblastic anemia 1";"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050487083.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_050472727.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050481457.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_050491580.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050492119.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_050492702.1	12	MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5870;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5871	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_050474749.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050492106.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482820.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050491887.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
XP_050476052.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050483323.1	9	Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695	"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation"
XP_050471023.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050475483.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-381676	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_050479103.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_050480921.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_050492867.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050471009.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050478143.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_050479897.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050469566.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050472811.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_050478018.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050481167.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050483279.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050495341.1	11	Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631	"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility"
XP_050490153.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050479979.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050472573.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121	"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_050487975.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050483504.1	3	Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078	"GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_050487257.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050476385.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482802.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050480104.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050485614.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725	"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050493522.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050486714.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050484201.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_050490670.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050478455.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050485354.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050482397.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050470183.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3232118	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors"
XP_050477485.1	24	Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-6814122	"Glucagon-type ligand receptors";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Ca2+ pathway";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050479703.1	7	Reactome: R-HSA-8957275;Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-140837;Reactome: R-HSA-114608	"Post-translational protein phosphorylation";"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation";"Platelet degranulation"
XP_050473967.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050476101.1	16	MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-2046105;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-2046106;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Linoleic acid (LA) metabolism";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"alpha-linolenic acid (ALA) metabolism";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050473684.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050484471.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism"
XP_050469647.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050475174.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050473441.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_050477179.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050495356.1	11	Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631	"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility"
XP_050490922.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_050494499.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050470373.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050487035.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050482790.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050477312.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050473569.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion"
XP_050488262.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050473816.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050477149.1	17	Reactome: R-HSA-74259;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-6608;MetaCyc: PWY-6644;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1	"Purine catabolism";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Neutrophil degranulation";"Guanosine nucleotides degradation III";"Fluoroacetate and fluorothreonine biosynthesis";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage III";"Pyrimidine metabolism"
XP_050471912.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050493583.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050476887.1	29	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-6803204;Reactome: R-HSA-5693571;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-6803207;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-349425;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-69541;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607	"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Nonhomologous End-Joining (NHEJ)";"Human cytomegalovirus infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"Human papillomavirus infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"TP53 Regulates Transcription of Caspase Activators and Caspases";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Stabilization of p53";"Regulation of TP53 Degradation";"Thermogenesis";"Relaxin signaling pathway";"Processing of DNA double-strand break ends"
XP_050483075.1	8	KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050475045.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050471848.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050478102.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_050475976.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050496678.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050491931.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050492473.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050491539.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050486650.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050496932.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050487569.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050470709.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_050485632.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_050475967.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050477608.1	19	Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity"
XP_050496964.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050479808.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-983695	"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_050470685.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism"
XP_050484825.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050475203.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_050472885.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050484153.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050485012.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050488172.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050482506.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_050479894.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050474104.1	6	MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_050488052.1	4	KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16	"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_050494232.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050483123.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050496073.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241	"Tryptophan metabolism";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import"
XP_050491023.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050471409.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050470792.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050476472.1	4	Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050492344.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050480246.1	10	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_050473254.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050485019.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050487036.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050485804.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050479134.1	6	MetaCyc: PWY-2942;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-8088;MetaCyc: PWY-5097;KEGG: 00261+4.3.3.7	"L-lysine biosynthesis III";"Lysine biosynthesis";"L-lysine biosynthesis II";"Dipicolinate biosynthesis";"L-lysine biosynthesis VI";"Monobactam biosynthesis"
XP_050484327.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_050483294.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050475038.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050471292.1	60	Reactome: R-HSA-77346;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00281+4.2.1.17;KEGG: 00310+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7726;KEGG: 00650+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;Reactome: R-HSA-77310;MetaCyc: PWY-7656;MetaCyc: PWY-1361;Reactome: R-HSA-77348;MetaCyc: PWY-6944;MetaCyc: PWY-7654;KEGG: 00903+4.2.1.17;Reactome: R-HSA-77288;KEGG: 00720+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00380+4.2.1.17;KEGG: 00280+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;MetaCyc: PWY-6883;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-7007;MetaCyc: PWY-6945;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-5177;Reactome: R-HSA-1482798;KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5138;Reactome: R-HSA-77305;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-7778;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;MetaCyc: PWY-7216;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-6946;KEGG: 00592+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;MetaCyc: PWY-5789	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid degradation";"Geraniol degradation";"Lysine degradation";"Pyruvate fermentation to hexanol (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Butanoate metabolism";"Fermentation to 2-methylbutanoate";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Spodoptera littoralis pheromone biosynthesis";"Benzoyl-coa degradation I (aerobic)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Limonene and pinene degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Carbon fixation pathways in prokaryotes";"4-hydroxybenzoate biosynthesis III (plants)";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Geraniol degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Pyruvate fermentation to butanol II (engineered)";"Toluene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Methyl tert-butyl ether degradation";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Phenylalanine metabolism";"Fatty acid salvage";"Glutaryl-coa degradation";"Acyl chain remodeling of CL";"Aminobenzoate degradation";"beta-Alanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Butanoate metabolism";"Tryptophan metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"2-methylpropene degradation";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"Fatty acid degradation";"Fatty acid degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Fatty acid elongation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid elongation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"alpha-Linolenic acid metabolism";"Butanoate metabolism";"Benzoate degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_050474801.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050488564.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_050476051.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050485886.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050478987.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050474073.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-735	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid degradation";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis"
XP_050481808.1	6	Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12	"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_050481992.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-1433559	"Neddylation";"Regulation of KIT signaling"
XP_050485417.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050487392.1	9	KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.25	"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Other glycan degradation"
XP_050487379.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050481490.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050477143.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-442720	"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_050471870.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050482562.1	11	Reactome: R-HSA-8940973;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5685938;Reactome: R-HSA-69231	"RUNX2 regulates osteoblast differentiation";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1"
XP_050475553.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050485483.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-447038	"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Trafficking of AMPA receptors";"Purine metabolism";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"NrCAM interactions"
XP_050473689.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050491862.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050475665.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050473914.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050481177.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050493850.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050490872.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050470707.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050495284.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_050493521.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050491600.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841	"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines"
XP_050485869.1	14	Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1474228;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695	"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of the extracellular matrix";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation"
XP_050469593.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050472464.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050491411.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_050492335.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050477514.1	19	Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825	"LDL clearance";"Platelet sensitization by LDL";"VLDL clearance";"VLDL assembly";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Chylomicron assembly";"Chylomicron clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis"
XP_050486679.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050490080.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050490696.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-166208	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling"
XP_050493581.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_050493876.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050481311.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_050482405.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050489479.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050482607.1	17	Reactome: R-HSA-2173796;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-111448;Reactome: R-HSA-113501;Reactome: R-HSA-2559580;Reactome: R-HSA-139915;Reactome: R-HSA-1912408;Reactome: R-HSA-6804114;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-2559585;Reactome: R-HSA-9616222;Reactome: R-HSA-69231;Reactome: R-HSA-1362300	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Activation of NOXA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oxidative Stress Induced Senescence";"Activation of PUMA and translocation to mitochondria";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Oncogene Induced Senescence";"Transcriptional regulation of granulopoiesis";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050472559.1	3	KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_050492877.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050491914.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050486928.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050473253.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050475855.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416	"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Synthesis of PA";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_050485288.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099	"Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling"
XP_050485750.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050469977.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050490799.1	7	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation"
XP_050486922.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050476820.1	6	Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18	"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_050478802.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050485786.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_050489532.1	10	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847	"Human papillomavirus infection";"mTOR signaling pathway";"Ub-specific processing proteases";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"HATs acetylate histones"
XP_050493789.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050484636.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050492302.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050469451.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050485100.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050472228.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050497111.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050482409.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050485099.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050476081.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050472198.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050475657.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050478130.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050481824.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_050476589.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_050485353.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050471523.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050478032.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_050486050.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050473003.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050490280.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050489813.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050487932.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050494328.1	3	Reactome: R-HSA-111465;Reactome: R-HSA-1660499;KEGG: 04660+2.7.10.2	"Apoptotic cleavage of cellular proteins";"Synthesis of PIPs at the plasma membrane";"T cell receptor signaling pathway"
XP_050494447.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050486085.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050481930.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050485707.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-mediated anterograde transport"
XP_050486352.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050496983.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050493673.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050479888.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050491480.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497	"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Kinesins";"Recycling pathway of L1";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050493206.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176407	"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_050493093.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050491924.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis"
XP_050484667.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050471477.1	13	MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6370;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261	"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate glutathione cycle"
XP_050479995.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050483788.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I"
XP_050490505.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050472086.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
XP_050493542.1	14	KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4	"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism"
XP_050475585.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050482293.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_050492790.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050491013.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050476232.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050475081.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050471310.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_050481614.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050472578.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122	"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_050480506.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050485326.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_050483071.1	8	KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050471911.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050478386.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050478795.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050490876.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050488642.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_050485692.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"Aggrephagy";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050496397.1	8	Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050469574.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-180746	"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein"
XP_050473568.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050470803.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050475204.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_050480713.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050480919.1	24	Reactome: R-HSA-8963896;Reactome: R-HSA-5610783;Reactome: R-HSA-163560;Reactome: R-HSA-432040;Reactome: R-HSA-5610780;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-5687128;Reactome: R-HSA-111931;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610785;Reactome: R-HSA-8853659;Reactome: R-HSA-422356;Reactome: R-HSA-5621575;Reactome: R-HSA-163615;Reactome: R-HSA-4420097;Reactome: R-HSA-9634600;Reactome: R-HSA-392517;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-163358	"HDL assembly";"Degradation of GLI2 by the proteasome";"Triglyceride catabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Degradation of GLI1 by the proteasome";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"MAPK6/MAPK4 signaling";"PKA-mediated phosphorylation of CREB";"mTOR signaling pathway";"GLI3 is processed to GLI3R by the proteasome";"RET signaling";"Regulation of insulin secretion";"CD209 (DC-SIGN) signaling";"PKA activation";"VEGFA-VEGFR2 Pathway";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Rap1 signalling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA-mediated phosphorylation of key metabolic factors"
XP_050492868.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050487855.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_050481332.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050482065.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050487959.1	4	KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20	"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism"
XP_050471858.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050486401.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_050471299.1	9	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-69017;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-68827;Reactome: R-HSA-68689	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex"
XP_050484670.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_050488396.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050473004.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050476952.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050471156.1	7	MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-7456	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation"
XP_050489447.1	7	Reactome: R-HSA-74217;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-6610;MetaCyc: PWY-7805	"Purine salvage";"Purine metabolism";"Glyphosate degradation III";"Neutrophil degranulation";"Adenine and adenosine salvage II";"Adenine salvage";"(aminomethyl)phosphonate degradation"
XP_050480712.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050479114.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050470229.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_050476686.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050490041.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050469587.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050489602.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050476769.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050487974.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050491393.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050478691.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174084	"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_050475463.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050484135.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050493455.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection"
XP_050492533.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050472242.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050481290.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050475108.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_050474428.1	7	Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism"
XP_050495778.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050479336.1	26	Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-9614657;Reactome: R-HSA-3214847;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408	"RORA activates gene expression";"Circadian Clock";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"FOXO-mediated transcription of cell death genes";"HATs acetylate histones";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"RUNX3 regulates NOTCH signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation"
XP_050489653.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_050483377.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050486014.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050472256.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050491990.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050485480.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-447038	"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"NrCAM interactions"
XP_050474092.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050475828.1	10	MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"D-galactose detoxification";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050482166.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050470338.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050494367.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050471651.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050483599.1	14	Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-113418	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex"
XP_050493394.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_050479463.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-2586552	"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Signaling by Leptin"
XP_050485328.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_050496890.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_050469528.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050477539.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway"
XP_050490497.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050489183.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_050492653.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_050469416.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_050474751.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050474740.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050470098.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_050486356.1	9	KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00400+2.6.1.5;Reactome: R-HSA-8963684	"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Tyrosine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine catabolism"
XP_050473543.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy"
XP_050472584.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050479675.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050486903.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_050482273.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050475210.1	9	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050483168.1	6	Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050481164.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050488548.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-426486	"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis"
XP_050473984.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050488576.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_050474727.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050469423.1	18	Reactome: R-HSA-6790901;Reactome: R-HSA-166208;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"rRNA modification in the nucleus and cytosol";"mTORC1-mediated signalling";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_050473346.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050485522.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050478655.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_050469790.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_050494756.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050475558.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050494128.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050479895.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050485540.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_050472007.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050471682.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_050470105.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050481533.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493159.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050490694.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050496608.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050492990.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683	"Selenocompound metabolism";"Selenate reduction";"Sulfite oxidation III";"Sulfur metabolism";"Purine metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfur metabolism";"Assimilatory sulfate reduction III"
XP_050488275.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050488748.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050490815.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050492246.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050470562.1	4	Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4	"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism"
XP_050476159.1	5	Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050482342.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050475969.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050490251.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050478581.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050490412.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050489460.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_050486707.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050477283.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594	"PKA activation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events"
XP_050473583.1	5	MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Heme biosynthesis"
XP_050474839.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168	"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050488784.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050490739.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"VLDL clearance";"Platelet sensitization by LDL";"LDL clearance";"VLDL assembly";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Clathrin-mediated endocytosis"
XP_050484677.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920	"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_050479912.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_050479913.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050475589.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050470571.1	4	MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis"
XP_050477109.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050472449.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050475707.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379	"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Late Events"
XP_050477544.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_050481484.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_050496436.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050483080.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68827	"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_050490288.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050489896.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050470724.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_050493991.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050488954.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050470753.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050473861.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050490462.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050473423.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_050492108.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_050493647.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050469900.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050475040.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050474343.1	4	Reactome: R-HSA-4570464;Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-72163	"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"mRNA Splicing - Major Pathway"
XP_050476891.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050482454.1	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050474055.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_050485727.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050475587.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_050486269.1	12	Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression"
XP_050478871.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050469602.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050486574.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050494218.1	7	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050489715.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_050475163.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050471369.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_050472170.1	3	MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_050483284.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050481660.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_050476866.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050483382.1	20	KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288	"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_050480338.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050486541.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050488972.1	4	KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_050496412.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_050496845.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050476888.1	6	KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050472804.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050473682.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050484889.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050478133.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050489168.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-202433;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;Reactome: R-HSA-9027277;Reactome: R-HSA-2029485;MetaCyc: PWY-6351;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204	"FCERI mediated Ca+2 mobilization";"Generation of second messenger molecules";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Role of phospholipids in phagocytosis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol"
XP_050485319.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism"
XP_050470010.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_050470918.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050478362.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050489464.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050479513.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050469962.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050479668.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050480010.1	24	Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218921;KEGG: 05163+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05165+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-2730905	"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"RSK activation";"VEGFR2 mediated cell proliferation";"Human cytomegalovirus infection";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Activation of AKT2";"Human papillomavirus infection";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Role of LAT2/NTAL/LAB on calcium mobilization"
XP_050482568.1	11	Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-5685938	"Myogenesis";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)"
XP_050482924.1	11	Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050477030.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050473222.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_050486850.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050471924.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050470186.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050493951.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050475985.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050473995.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050481334.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050477293.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050488331.1	6	MetaCyc: PWY-7900;MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050485305.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050491498.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_050478287.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050488296.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_050487364.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050481675.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050470246.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050490359.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050493496.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050488314.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050487990.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050487946.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_050480753.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress"
XP_050475569.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050489523.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050491488.1	7	Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6470;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
XP_050470188.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050475847.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050471235.1	18	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"mTORC1-mediated signalling";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050486005.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_050491130.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050471686.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_050496523.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050483777.1	10	Reactome: R-HSA-977225;Reactome: R-HSA-2453864;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-3000171;Reactome: R-HSA-2453902	"Amyloid fiber formation";"Retinoid cycle disease events";"Retinoid metabolism and transport";"Neutrophil degranulation";"Urate conversion to allantoin III";"Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)"
XP_050488269.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050486389.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050474939.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050484435.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050490897.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050482257.1	3	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_050479801.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-983695	"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_050492454.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_050483089.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation"
XP_050492830.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_050490129.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050475216.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050474287.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050478860.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Neutrophil degranulation";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_050475473.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_050477562.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050477552.1	4	Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-162699	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose"
XP_050484474.1	26	Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2132295	"Recycling pathway of L1";"Kinesins";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation"
XP_050481439.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050491868.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050478103.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050493954.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050471521.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050470215.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050478504.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050487647.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation"
XP_050474057.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050471225.1	11	Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_050476747.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050481741.1	13	Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1	"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway"
XP_050490582.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050488659.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_050481449.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050471859.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050487720.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_050495921.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050486199.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050478238.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050480511.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050471300.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69017;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress"
XP_050474399.1	3	KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286	"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation"
XP_050478205.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050482925.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050492993.1	12	Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction";"Purine metabolism"
XP_050471418.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050472557.1	3	KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_050490808.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050488795.1	6	Reactome: R-HSA-2892245;Reactome: R-HSA-3769402;Reactome: R-HSA-8986944;Reactome: R-HSA-6785807;Reactome: R-HSA-452723;Reactome: R-HSA-2892247	"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Deactivation of the beta-catenin transactivating complex";"Transcriptional Regulation by MECP2";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation of pluripotent stem cells";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"
XP_050483145.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050475984.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050470113.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050470976.1	13	Reactome: R-HSA-3371511;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-532668;Reactome: R-HSA-5689896;Reactome: R-HSA-382556;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895;Reactome: R-HSA-8876725	"HSF1 activation";"Aggrephagy";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Ovarian tumor domain proteases";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis";"Protein methylation"
XP_050486165.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_050494757.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050485527.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050472229.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050487237.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050473258.1	5	KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_050481613.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050480094.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050472141.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072	"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050470413.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050487574.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628	"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_050493097.1	10	Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554	"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050472123.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050484389.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050470420.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050483989.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_050482032.1	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_050477614.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066	"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation";"Ion transport by P-type ATPases";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_050482872.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050470867.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_050479485.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050481908.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050474079.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050482241.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050489519.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050484466.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6364	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_050489649.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_050483767.1	10	Reactome: R-HSA-977225;Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;Reactome: R-HSA-975634;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;MetaCyc: PWY-5691;MetaCyc: PWY-7394	"Amyloid fiber formation";"Retinoid cycle disease events";"Neutrophil degranulation";"Retinoid metabolism and transport";"Urate conversion to allantoin III";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I";"Urate conversion to allantoin II"
XP_050475374.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050482398.1	4	Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;Reactome: R-HSA-2393930;KEGG: 00240+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Purine metabolism";"Phosphate bond hydrolysis by NUDT proteins";"Pyrimidine metabolism"
XP_050480819.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050492962.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050478552.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_050486461.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050489930.1	19	MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;Reactome: R-HSA-75105;MetaCyc: PWY-5537;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;Reactome: R-HSA-163765	"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression"
XP_050485752.1	7	MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7886;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191	"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PC"
XP_050477538.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050478721.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"Recycling pathway of L1";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"HCMV Early Events";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport"
XP_050485444.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-202424	"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling"
XP_050472026.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050482058.1	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_050484369.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050489618.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050490531.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497	"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Recycling pathway of L1";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050488272.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050493546.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050479994.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050492798.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_050479049.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050493582.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_050475638.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050486585.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050493547.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050480339.1	2	Reactome: R-HSA-2129379;Reactome: R-HSA-189085	"Molecules associated with elastic fibres";"Digestion of dietary carbohydrate"
XP_050490300.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_050470801.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050479401.1	5	Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-901042	"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle"
XP_050478599.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050471017.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050470419.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050484324.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050472821.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_050487985.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050485568.1	52	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-76066;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167172	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome"
XP_050485566.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050494213.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_050484691.1	6	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050478485.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665	"Clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_050481973.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050482080.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050486654.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050493948.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050470156.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_050478739.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050478776.1	8	KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268	"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_050485523.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050493649.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050491745.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050471543.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050474750.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050474510.1	10	KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Sphingolipid metabolism";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"HS-GAG degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_050471756.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050477039.1	7	MetaCyc: PWY-6840;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2	"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism"
XP_050496793.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050486905.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_050492115.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_050478236.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050475743.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050493738.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_050484905.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050481960.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050490034.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050473416.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050474523.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050494063.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_050486550.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174154	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin"
XP_050481321.1	17	Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167287;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112382	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Formation of RNA Pol II elongation complex"
XP_050472436.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050485729.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050491856.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050475208.1	9	KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway"
XP_050472024.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050489163.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050496392.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050470623.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050476489.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050480775.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050485616.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_050481043.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050469622.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_050496948.1	4	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050487327.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050474874.1	3	Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050486513.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050486610.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6796648	"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050476837.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050475827.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_050493189.1	10	MetaCyc: PWY-7187;KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7199;Reactome: R-HSA-499943;Reactome: R-HSA-69205;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"One carbon pool by folate";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_050481505.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050497023.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_050480128.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050482178.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050475343.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_050485330.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_050472376.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050492357.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050474506.1	10	KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23	"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_050473559.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_050480803.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050480748.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050483809.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050496396.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_050489927.1	19	KEGG: 00020+2.3.3.8;MetaCyc: PWY-5537;MetaCyc: PWY-5172;Reactome: R-HSA-163765;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;Reactome: R-HSA-75105;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8	"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_050493348.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050478116.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050479124.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050496382.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050474732.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050479462.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-2586552	"Prolactin receptor signaling";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin"
XP_050496797.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050483796.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_050482283.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050483014.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-7761	"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)"
XP_050474802.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050478738.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP"
XP_050470607.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050473420.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_050473983.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050488828.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050484090.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050485573.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050484376.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050480548.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_050472796.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050493808.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050489108.1	6	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050471099.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050482333.1	5	Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism"
XP_050478597.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050474434.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050474415.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050473488.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050483082.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation"
XP_050471471.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050493428.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050478054.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_050488876.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050478202.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050493510.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050478800.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050483318.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation"
XP_050493632.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050484538.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050483579.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050488937.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050482415.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050495912.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050475109.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_050494239.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050482272.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050481700.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050474384.1	15	Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_050489156.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050481706.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050480516.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050475598.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050472299.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050492516.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050484640.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050469941.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050489105.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050488565.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_050486820.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050481319.1	14	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_050491171.1	17	MetaCyc: PWY-6969;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II"
XP_050481014.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050473412.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050480121.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050472301.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050475363.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050488561.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_050492992.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683	"Selenocompound metabolism";"Selenate reduction";"Sulfite oxidation III";"Sulfur metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfur metabolism";"Assimilatory sulfate reduction III"
XP_050485327.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050482285.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050472126.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase"
XP_050482821.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050484624.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050490265.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050496592.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050492844.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050471561.1	3	MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K"
XP_050493244.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_050474509.1	10	KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2160916	"Galactose metabolism";"HS-GAG degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation"
XP_050491492.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes"
XP_050492474.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050470966.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050480504.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050483692.1	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_050485652.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050489011.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050496450.1	34	Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-6782135	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER"
XP_050470884.1	4	Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9	"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism"
XP_050471861.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050479809.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-2871809	"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Ca2+ pathway";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization"
XP_050489256.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050488929.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050474253.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050475968.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050485487.1	8	Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736	"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors"
XP_050480235.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050486946.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050471407.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_050496586.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050473433.1	3	MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_050484499.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050489664.1	12	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050485485.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-399719	"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Purine metabolism";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Trafficking of AMPA receptors"
XP_050490565.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_050485162.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050475611.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050486028.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050469753.1	18	Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051	"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I"
XP_050471775.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243	"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050480804.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_050473325.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-5674400	"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_050474778.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050483331.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_050490124.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050493953.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050477740.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050487635.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050492361.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050490979.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050490400.1	13	Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-445989	"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_050493317.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050482801.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050484006.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050474725.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050472004.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050479238.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050481981.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050493130.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050470821.1	8	Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_050485364.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_050480813.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050478288.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050482025.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050493134.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050476851.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050484690.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_050474480.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301	"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Phytate degradation I";"Inositol phosphate metabolism";"Myo-inositol biosynthesis"
XP_050492948.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050483733.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050470690.1	33	Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168271	"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_050485153.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050476832.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050485679.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins"
XP_050475641.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050476148.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257	"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion"
XP_050494214.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_050469995.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050473730.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050476918.1	12	KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278	"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III"
XP_050475803.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050474800.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050475236.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport"
XP_050481094.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050475576.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050489934.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_050487591.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050471919.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_050478484.1	18	MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-7115;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-5392;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism"
XP_050491859.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050479845.1	11	KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007	"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events"
XP_050479887.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050489617.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050477625.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
XP_050492834.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050477823.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050497081.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050477593.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952	"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions"
XP_050486608.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_050491133.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050478258.1	8	KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050492661.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050489822.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050486829.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050489034.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050477592.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9609736	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors"
XP_050474450.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050492869.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_050484965.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050474737.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050480727.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-180746	"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein"
XP_050471368.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling"
XP_050485335.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972	"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)"
XP_050482806.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050494010.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050487828.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050487081.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_050493000.1	12	MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25	"Sulfate activation for sulfonation";"Purine metabolism";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenocompound metabolism";"Selenate reduction";"Sulfite oxidation III";"Sulfur metabolism"
XP_050496957.1	5	Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720	"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis"
XP_050492321.1	12	KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Stachyose degradation"
XP_050483032.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050486359.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050488376.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050469935.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859	"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly"
XP_050474449.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050473814.1	11	Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-6549;MetaCyc: PWY-381	"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)"
XP_050469677.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_050475594.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050469818.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050496368.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1989781	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression"
XP_050493195.1	19	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-3214858;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-8876725;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"RMTs methylate histone arginines";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Protein methylation";"Viral mRNA Translation"
XP_050477284.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events"
XP_050470078.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation"
XP_050472232.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050474271.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050472847.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050474662.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050480430.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_050489300.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050478148.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_050479941.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050479889.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050482127.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050474094.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050479389.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050493177.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050493393.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_050481017.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050477178.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050491630.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050474780.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050486177.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050483923.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050484950.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050478396.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050481179.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050488312.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050480833.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_050472315.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050490853.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050485236.1	13	Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4341670;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-2206308;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"HS-GAG degradation";"Galactose metabolism";"Defective NEU1 causes sialidosis";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Neutrophil degranulation";"MPS IV - Morquio syndrome B";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism"
XP_050483911.1	22	MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-5353;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6958;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-7606	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_050477595.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952	"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"RAF activation";"Ion transport by P-type ATPases";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions"
XP_050489018.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050477877.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050481335.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050477783.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050493726.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050484541.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050485759.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-429947;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050472116.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050487604.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050471062.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050473614.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050483031.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050485932.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050491880.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050492527.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050470868.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_050473938.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050480377.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050475032.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050481042.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050491065.1	18	Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417	"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Synthesis of PA";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_050483360.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_050472082.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation"
XP_050484751.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050485603.1	52	Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-76066;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-5601884	"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis"
XP_050484687.1	6	MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952	"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_050476368.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050485784.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-5617472;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050472777.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_050470279.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050491529.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050489257.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050478308.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050476881.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050470960.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050490976.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050489325.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500	"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_050482624.1	7	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16	"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism"
XP_050481073.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050481487.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050486210.1	6	Reactome: R-HSA-204005;Reactome: R-HSA-416993;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050475684.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_050477295.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050486999.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050484781.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape"
XP_050471022.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050493242.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050482518.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050474637.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050491503.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines"
XP_050493796.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050491960.1	16	Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_050485796.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050471987.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399	"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_050486286.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050470189.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050494050.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_050486197.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050485743.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050470435.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050488377.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050481740.1	13	Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-3928663;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1	"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection";"EPHB-mediated forward signaling";"EPHA-mediated growth cone collapse";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection"
XP_050479246.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050469535.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050484247.1	7	Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838	"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO"
XP_050473918.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050497047.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050474479.1	7	MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25	"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phytate degradation I";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis"
XP_050469901.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050482349.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050485282.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050486291.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050481485.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050487003.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050486280.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050480614.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050479551.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_050470769.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050493068.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050489013.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050470483.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050471511.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_050481797.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_050483378.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050479870.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050496212.1	5	KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling"
XP_050473565.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050474812.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050487782.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050474723.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050484326.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050481984.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050472940.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050492317.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050488715.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050484952.1	5	MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism"
XP_050483182.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050478302.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050493723.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050477606.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000	"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Long-term potentiation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation"
XP_050476321.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050469883.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050471406.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_050471246.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity"
XP_050485870.1	14	Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-205043	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NRIF signals cell death from the nucleus"
XP_050490405.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050493203.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050490410.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050487435.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050483351.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050473226.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050469920.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050484124.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050479422.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050483807.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050479421.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050477404.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050485402.1	17	KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-200425	"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Carnitine metabolism"
XP_050478854.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050478000.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050478985.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050471607.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_050477258.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050471155.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-882	"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_050473828.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade"
XP_050478569.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050479970.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050490159.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_050491923.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050471856.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050470723.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050485699.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins"
XP_050470881.1	14	KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Cyanoamino acid metabolism";"Photorespiration ";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Glycine betaine degradation I";"Methane metabolism";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_050485795.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050472794.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050485022.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050479553.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_050472725.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050472292.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050485016.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050493722.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050491980.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_050488566.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_050472555.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_050479047.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050475550.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050472642.1	5	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050477369.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050483184.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050485493.1	12	Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;MetaCyc: PWY-7221	"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis"
XP_050484861.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050496618.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050472749.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050471668.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050485563.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_050482452.1	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050470220.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050480631.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050493706.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_050483379.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050479113.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050489509.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050487695.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050478208.1	16	Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200	"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of HIV elongation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050485404.1	17	MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-200425	"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Carnitine metabolism"
XP_050487055.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050482170.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050476358.1	5	MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614	"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_050472252.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050481342.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050478244.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_050484527.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050488649.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050472253.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050473432.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol"
XP_050480134.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050488600.1	4	Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250;Reactome: R-HSA-947581	"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050474507.1	10	KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Sphingolipid metabolism";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_050473641.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_050483099.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050485097.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050480737.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050476583.1	10	KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050492608.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050489035.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050472455.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins"
XP_050492320.1	12	KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;MetaCyc: PWY-3801;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9	"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Glycerolipid metabolism"
XP_050486268.1	12	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050494240.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050471570.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050473870.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_050492609.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_050477738.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050483784.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15	"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism"
XP_050476942.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_050479939.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_050488392.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050491719.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050480453.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050480315.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050489486.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050484888.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_050496359.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472	"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050488197.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4	"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Surfactant metabolism";"Neutrophil degranulation";"Purine metabolism"
XP_050493345.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050492125.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_050486080.1	5	Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)"
XP_050472280.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-168333	"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050481214.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050486921.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050491471.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_050491002.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050470906.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-7736	"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis"
XP_050473114.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_050489298.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050487114.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"UCH proteinases";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin"
XP_050492337.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
XP_050481219.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050485928.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050494759.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050493693.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-198323	"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"mTOR signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol"
XP_050485517.1	13	Reactome: R-HSA-2243919;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490	"Crosslinking of collagen fibrils";"Collagen chain trimerization";"NCAM1 interactions";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Extracellular matrix organization";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Laminin interactions";"Collagen degradation"
XP_050477253.1	16	Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-201722;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-3214847;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607	"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HATs acetylate histones";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends"
XP_050469632.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050473274.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050486968.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050475575.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050489271.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_050491134.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050492144.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_050482416.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050471096.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050489331.1	13	Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-8964038	"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"LDL clearance"
XP_050491050.1	7	MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25	"Myo-inositol biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_050475260.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050484765.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050482211.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050471981.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape"
XP_050470604.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050475104.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228	"Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix"
XP_050469877.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050480325.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050473481.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050479786.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-8061	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification II"
XP_050485612.1	14	MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050482788.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050478544.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050479090.1	7	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050469591.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050480093.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050476899.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050488671.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050496714.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_050477443.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_050472085.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation"
XP_050481907.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050485937.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050473658.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050490247.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050485447.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050472887.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050489290.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_050486794.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_050473224.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050492291.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050476717.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050477082.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation"
XP_050470802.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050471693.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050482967.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050479844.1	11	KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097	"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway"
XP_050496950.1	4	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050488522.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050475489.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050472993.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050488731.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050481965.1	8	KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-922	"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway I"
XP_050490007.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050490456.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050474982.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050486792.1	7	MetaCyc: PWY-8026;KEGG: 00100+1.3.1.70;MetaCyc: PWY-6074;MetaCyc: PWY-7154;Reactome: R-HSA-191273;MetaCyc: PWY-2541;Reactome: R-HSA-9022692	"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Zymosterol biosynthesis";"Ergosterol biosynthesis II";"Cholesterol biosynthesis";"Phytosterol biosynthesis (plants)";"Regulation of MECP2 expression and activity"
XP_050486353.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050474634.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050476708.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050473422.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_050486804.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_050471263.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050482792.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050473657.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050480905.1	12	KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476	"Human papillomavirus infection";"NRAGE signals death through JNK";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events"
XP_050479576.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050478922.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050485959.1	7	Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-6737	"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation II";"Starch and sucrose metabolism";"Neutrophil degranulation";"Starch degradation V"
XP_050484881.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_050473161.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244	"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Long-term potentiation"
XP_050484951.1	5	MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism"
XP_050482752.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050479270.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050473766.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050486340.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050494176.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_050478482.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050483409.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050483142.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050473421.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050494013.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050479893.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050482710.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_050493584.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_050491920.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis"
XP_050485698.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Aggrephagy"
XP_050484403.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050477158.1	6	Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_050493783.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_050470914.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_050472293.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232	"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_050489808.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_050470880.1	14	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661;KEGG: 00630+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1	"Metabolism of folate and pterines";"Folate polyglutamylation";"Methane metabolism";"Folate transformations II (plants)";"Glycine betaine degradation I";"Glyoxylate and dicarboxylate metabolism";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Photorespiration ";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"One carbon pool by folate";"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism"
XP_050478582.1	179	Reactome: R-HSA-174154;Reactome: R-HSA-69231;Reactome: R-HSA-8863795;Reactome: R-HSA-975956;Reactome: R-HSA-2559585;Reactome: R-HSA-1169408;Reactome: R-HSA-175474;Reactome: R-HSA-168927;Reactome: R-HSA-201681;Reactome: R-HSA-5607764;Reactome: R-HSA-2672351;Reactome: R-HSA-2871837;Reactome: R-HSA-179409;Reactome: R-HSA-400253;Reactome: R-HSA-2173796;Reactome: R-HSA-8939902;Reactome: R-HSA-937042;Reactome: R-HSA-5675482;Reactome: R-HSA-5689877;Reactome: R-HSA-5658442;Reactome: R-HSA-5656169;Reactome: R-HSA-75815;Reactome: R-HSA-2559582;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-3322077;Reactome: R-HSA-6781823;Reactome: R-HSA-202424;Reactome: R-HSA-9633012;Reactome: R-HSA-936964;Reactome: R-HSA-1169091;Reactome: R-HSA-8866652;Reactome: R-HSA-5357956;Reactome: R-HSA-8866654;Reactome: R-HSA-901032;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-8948751;Reactome: R-HSA-975110;Reactome: R-HSA-2173791;Reactome: R-HSA-9010553;Reactome: R-HSA-5654733;Reactome: R-HSA-5689901;Reactome: R-HSA-937072;Reactome: R-HSA-917937;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-5696394;Reactome: R-HSA-72689;Reactome: R-HSA-5205685;Reactome: R-HSA-937041;Reactome: R-HSA-8856825;Reactome: R-HSA-195253;Reactome: R-HSA-9014325;Reactome: R-HSA-1358803;Reactome: R-HSA-975163;Reactome: R-HSA-68949;Reactome: R-HSA-8875360;Reactome: R-HSA-8948747;Reactome: R-HSA-6783310;Reactome: R-HSA-450302;Reactome: R-HSA-9613829;Reactome: R-HSA-2408557;Reactome: R-HSA-5610783;Reactome: R-HSA-110312;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-156827;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-209543;Reactome: R-HSA-5676590;Reactome: R-HSA-110314;Reactome: R-HSA-1799339;Reactome: R-HSA-182971;Reactome: R-HSA-69541;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-9020702;Reactome: R-HSA-8876493;Reactome: R-HSA-2173795;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-205043;Reactome: R-HSA-3134975;Reactome: R-HSA-937039;Reactome: R-HSA-5654727;Reactome: R-HSA-209560;Reactome: R-HSA-1295596;Reactome: R-HSA-187577;Reactome: R-HSA-5693607;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-162588;Reactome: R-HSA-5654726;Reactome: R-HSA-5610785;Reactome: R-HSA-5685942;Reactome: R-HSA-975957;Reactome: R-HSA-912631;Reactome: R-HSA-174048;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-5689896;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-9637628;Reactome: R-HSA-156902;Reactome: R-HSA-5678895;Reactome: R-HSA-2691232;Reactome: R-HSA-174084;Reactome: R-HSA-450321;Reactome: R-HSA-2122947;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-9645460;Reactome: R-HSA-6807004;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-6782135;Reactome: R-HSA-917729;Reactome: R-HSA-192823;Reactome: R-HSA-5668541;Reactome: R-HSA-72764;Reactome: R-HSA-5696397;Reactome: R-HSA-6781827;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-3785653;Reactome: R-HSA-8939236;Reactome: R-HSA-445989;Reactome: R-HSA-9013973;Reactome: R-HSA-5654732;Reactome: R-HSA-9033241;Reactome: R-HSA-68827;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-168928;Reactome: R-HSA-6804757;Reactome: R-HSA-6804760;Reactome: R-HSA-5675221;Reactome: R-HSA-1236382;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8849469;Reactome: R-HSA-2565942;Reactome: R-HSA-5693565;Reactome: R-HSA-4641263;Reactome: R-HSA-8856828;Reactome: R-HSA-532668;Reactome: R-HSA-5684264;Reactome: R-HSA-2173788;Reactome: R-HSA-69601;Reactome: R-HSA-5696395;Reactome: R-HSA-382556;Reactome: R-HSA-977225;Reactome: R-HSA-1253288;Reactome: R-HSA-2979096;Reactome: R-HSA-69481;Reactome: R-HSA-936440;Reactome: R-HSA-168638;Reactome: R-HSA-9636383;Reactome: R-HSA-2559580;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-3769402;Reactome: R-HSA-174490;Reactome: R-HSA-5696400;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-5655862;Reactome: R-HSA-110320	"APC/C:Cdc20 mediated degradation of Securin";"Cyclin D associated events in G1";"Downregulation of ERBB2 signaling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Oncogene Induced Senescence";"ISG15 antiviral mechanism";"Assembly Of The HIV Virion";"TICAM1, RIP1-mediated IKK complex recruitment";"TCF dependent signaling in response to WNT";"CLEC7A (Dectin-1) signaling";"Stimuli-sensing channels";"FCERI mediated NF-kB activation";"APC-Cdc20 mediated degradation of Nek2A";"Circadian Clock";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of RUNX2 expression and activity";"IRAK2 mediated activation of TAK1 complex";"Regulation of necroptotic cell death";"Josephin domain DUBs";"Regulation of RAS by GAPs";"Termination of translesion DNA synthesis";"Ubiquitin-dependent degradation of Cyclin D";"Senescence-Associated Secretory Phenotype (SASP)";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Glycogen synthesis";"Formation of TC-NER Pre-Incision Complex";"Downstream TCR signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Activation of NF-kappaB in B cells";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TNFR1-induced NFkappaB signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"ER Quality Control Compartment (ERQC)";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN stability and activity";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of expression of SLITs and ROBOs";"Negative regulation of FGFR4 signaling";"Metalloprotease DUBs";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Iron uptake and transport";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"DNA Damage Recognition in GG-NER";"Formation of a pool of free 40S subunits";"Pink/Parkin Mediated Mitophagy";"IKK complex recruitment mediated by RIP1";"Cargo recognition for clathrin-mediated endocytosis";"Degradation of beta-catenin by the destruction complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downregulation of ERBB2:ERBB3 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Orc1 removal from chromatin";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of PTEN localization";"Fanconi Anemia Pathway";"activated TAK1 mediates p38 MAPK activation";"Chaperone Mediated Autophagy";"Selenocysteine synthesis";"Degradation of GLI2 by the proteasome";"Translesion synthesis by REV1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Hedgehog ligand biogenesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"p75NTR recruits signalling complexes";"NIK-->noncanonical NF-kB signaling";"Recognition of DNA damage by PCNA-containing replication complex";"SRP-dependent cotranslational protein targeting to membrane";"EGFR downregulation";"Stabilization of p53";"Neddylation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"Interleukin-1 signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"NRIF signals cell death from the nucleus";"Regulation of innate immune responses to cytosolic DNA";"IRAK1 recruits IKK complex";"Negative regulation of FGFR2 signaling";"NF-kB is activated and signals survival";"Spry regulation of FGF signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Processing of DNA double-strand break ends";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Budding and maturation of HIV virion";"Negative regulation of FGFR1 signaling";"GLI3 is processed to GLI3R by the proteasome";"HDR through Homologous Recombination (HRR)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of signaling by CBL";"APC/C:Cdc20 mediated degradation of Cyclin B";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ovarian tumor domain proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Modulation by Mtb of host immune system";"Peptide chain elongation";"Defective CFTR causes cystic fibrosis";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Autodegradation of Cdh1 by Cdh1:APC/C";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOTCH1 Intracellular Domain Regulates Transcription";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of MET activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Dual incision in TC-NER";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Viral mRNA Translation";"TNFR2 non-canonical NF-kB pathway";"Eukaryotic Translation Termination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Myoclonic epilepsy of Lafora";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulation of FGFR3 signaling";"Peroxisomal protein import";"CDT1 association with the CDC6:ORC:origin complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Methylation";"Negative regulation of MAPK pathway";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of FZD by ubiquitination";"Clathrin-mediated endocytosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downregulation of TGF-beta receptor signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Formation of Incision Complex in GG-NER";"ABC-family proteins mediated transport";"Amyloid fiber formation";"Downregulation of ERBB4 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"G2/M Checkpoints";"Negative regulators of DDX58/IFIH1 signaling";"NOD1/2 Signaling Pathway";"Prevention of phagosomal-lysosomal fusion";"Oxidative Stress Induced Senescence";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Deactivation of the beta-catenin transactivating complex";"Membrane binding and targetting of GAG proteins";"Dual Incision in GG-NER";"Late endosomal microautophagy";"Aggrephagy";"Translesion synthesis by POLK";"Translesion Synthesis by POLH"
XP_050490002.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_050474822.1	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_050490491.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050488067.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050484154.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050481436.1	15	Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050489538.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_050489198.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050475353.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050479255.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"Insulin receptor recycling"
XP_050478519.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation"
XP_050470464.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events"
XP_050494211.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_050489773.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050475350.1	4	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_050479688.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_050477232.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling"
XP_050483797.1	10	Reactome: R-HSA-977225;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17	"Amyloid fiber formation";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Neutrophil degranulation";"Urate conversion to allantoin III";"Purine metabolism"
XP_050480312.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050478542.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050476833.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050470827.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050477032.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050493949.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050471469.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050477268.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_050487191.1	34	Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885	"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins"
XP_050471878.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_050486770.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050485606.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050493028.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050480882.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_050480720.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300	"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_050493474.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050474739.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050482804.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050483752.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050483786.1	10	MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I"
XP_050475595.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050491005.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050489638.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050481489.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050488562.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_050494777.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050472260.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050488720.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050484871.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_050473002.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050478255.1	8	KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050482223.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050472125.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_050472572.1	7	MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-7282;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050484366.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050473431.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)"
XP_050487698.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050469745.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050488669.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050474607.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050470404.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050471806.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050493395.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050482662.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050496438.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050472079.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"G1/S-Specific Transcription";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_050476065.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050476233.1	5	Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2"
XP_050474734.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050477797.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050484777.1	6	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_050472648.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050475486.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-5610787	"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state"
XP_050489620.1	7	KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_050492365.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050472770.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050486491.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050487630.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050489815.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050476207.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050484967.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050475094.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050492692.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159231	"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_050495792.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_050475191.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_050478472.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050489487.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050493616.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050470234.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-432040	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_050492353.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050493816.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Arachidonic acid metabolism"
XP_050472437.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050481563.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050483991.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050480852.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050481159.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050490600.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_050471257.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050488930.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050481940.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050481181.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050484455.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050474738.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050489437.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050482686.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050473563.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050472318.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050486651.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050489507.1	7	KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-6124	"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II"
XP_050489455.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050473959.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050474096.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050481504.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050483333.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955	"MAP2K and MAPK activation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050478761.1	8	KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27	"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism"
XP_050470405.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050473429.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050489491.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050473164.1	13	KEGG: 05170+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human papillomavirus infection";"Signaling by moderate kinase activity BRAF mutants";"mTOR signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Thermogenesis";"Relaxin signaling pathway"
XP_050483325.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948	"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Platelet degranulation";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants"
XP_050473988.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050485018.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050472813.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_050486708.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050471216.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050471291.1	60	KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;Reactome: R-HSA-77285;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;KEGG: 00280+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-6944;Reactome: R-HSA-77348;MetaCyc: PWY-7654;MetaCyc: PWY-1361;Reactome: R-HSA-77288;KEGG: 00720+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7606;Reactome: R-HSA-77310;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-6863;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17;MetaCyc: PWY-5109;Reactome: R-HSA-77346;KEGG: 00281+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00362+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-6946;MetaCyc: PWY-7216;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;Reactome: R-HSA-77350;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00650+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-5138;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5177;Reactome: R-HSA-1482798;MetaCyc: PWY-6945;MetaCyc: PWY-7779;MetaCyc: PWY-7007;MetaCyc: PWY-7094;KEGG: 00360+4.2.1.17	"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Toluene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Geraniol degradation";"Pyruvate fermentation to butanol II (engineered)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Androstenedione degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Benzoyl-coa degradation I (aerobic)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Spodoptera littoralis pheromone biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Lysine degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to hexanol (engineered)";"Benzoate degradation";"Butanoate metabolism";"Fermentation to 2-methylbutanoate";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Geraniol degradation";"Fatty acid degradation";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoate degradation";"alpha-Linolenic acid metabolism";"Fatty acid elongation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fatty acid elongation";"Fatty acid degradation";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"2-methylpropene degradation";"Butanoate metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Tryptophan metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Aminobenzoate degradation";"beta-Alanine metabolism";"Glutaryl-coa degradation";"Acyl chain remodeling of CL";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"Methyl ketone biosynthesis (engineered)";"Fatty acid salvage";"Phenylalanine metabolism"
XP_050486791.1	7	Reactome: R-HSA-9022692;MetaCyc: PWY-2541;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.70;Reactome: R-HSA-191273;MetaCyc: PWY-6074;MetaCyc: PWY-7154	"Regulation of MECP2 expression and activity";"Phytosterol biosynthesis (plants)";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis";"Zymosterol biosynthesis";"Ergosterol biosynthesis II"
XP_050470928.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050480099.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050490503.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050470157.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_050474448.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050483433.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_050472194.1	12	MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-7901	"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine"
XP_050470479.1	11	Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"RORA activates gene expression";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_050470679.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_050480292.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050488941.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050487437.1	9	Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7117	"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_050473990.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050471220.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050494758.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050474559.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050493944.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_050483730.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050484539.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050485440.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_050489159.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050472733.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050483394.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050490301.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_050488867.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050478286.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050491831.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050485355.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050491069.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050493092.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050474966.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050469954.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050494744.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_050484903.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_050493148.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050480807.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050479930.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050485504.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050494009.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050491536.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050482445.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050481203.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050485084.1	40	Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167200	"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050496847.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_050481804.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_050492460.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050474118.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050470916.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050486099.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_050480225.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050494202.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_050487299.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050490589.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050491014.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050487399.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050490451.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050489483.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050472802.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050486570.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050483185.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050471849.1	18	KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-7383;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1	"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"(R)-cysteate degradation";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050485828.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050491401.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin"
XP_050484682.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050470316.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050476492.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_050477299.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050483065.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050483253.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050490579.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050486614.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174113	"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1"
XP_050473920.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050471464.1	14	Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events"
XP_050475207.1	9	Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection"
XP_050479203.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_050488270.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050479359.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050469821.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050469951.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050486003.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_050497022.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_050483091.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050492136.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050486553.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050486424.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236	"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Neddylation";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_050487044.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-918233	"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway"
XP_050475816.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050492114.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_050476571.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4	"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Synthesis of PC";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism"
XP_050493031.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050492127.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_050475491.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_050487254.1	5	Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;MetaCyc: PWY-7511	"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Protein ubiquitination"
XP_050493436.1	8	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050497114.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050474511.1	10	Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23	"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"HS-GAG degradation";"Other glycan degradation"
XP_050486964.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_050475592.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050484047.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_050482410.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050476218.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050478820.1	14	KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-434316;Reactome: R-HSA-1855204;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-418217;MetaCyc: PWY-6367;Reactome: R-HSA-399997;Reactome: R-HSA-112043	"Inositol phosphate metabolism";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Synthesis of IP3 and IP4 in the cytosol";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G beta:gamma signalling through PLC beta";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion";"PLC beta mediated events"
XP_050480802.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_050482072.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050482396.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050490228.1	52	Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163	"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway"
XP_050471470.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050497085.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050478515.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA"
XP_050482796.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050471280.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050491557.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050476933.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_050477696.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050476556.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_050493392.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050478495.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050481488.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050479122.1	4	Reactome: R-HSA-9031525;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8866427	"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"VLDLR internalisation and degradation"
XP_050487449.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050488601.1	4	Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;MetaCyc: PWY-7250	"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_050476760.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050475302.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050474223.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050473561.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050488931.1	83	Reactome: R-HSA-5654689;Reactome: R-HSA-1257604;Reactome: R-HSA-8875656;Reactome: R-HSA-8856825;Reactome: R-HSA-5654732;Reactome: R-HSA-5654695;Reactome: R-HSA-2730905;Reactome: R-HSA-5654706;Reactome: R-HSA-391160;Reactome: R-HSA-8851805;Reactome: R-HSA-8875360;Reactome: R-HSA-8853338;Reactome: R-HSA-9028335;Reactome: R-HSA-5655291;Reactome: R-HSA-389359;Reactome: R-HSA-74751;Reactome: R-HSA-5655253;Reactome: R-HSA-1236382;Reactome: R-HSA-9034864;Reactome: R-HSA-5655302;Reactome: R-HSA-5654720;Reactome: R-HSA-5654712;Reactome: R-HSA-8853659;Reactome: R-HSA-2424491;Reactome: R-HSA-8856828;Reactome: R-HSA-6811558;Reactome: R-HSA-1839117;Reactome: R-HSA-9607240;Reactome: R-HSA-180336;Reactome: R-HSA-983695;Reactome: R-HSA-375165;Reactome: R-HSA-5654719;Reactome: R-HSA-5654710;Reactome: R-HSA-182971;Reactome: R-HSA-180292;Reactome: R-HSA-9634285;Reactome: R-HSA-5654700;Reactome: R-HSA-912526;Reactome: R-HSA-5663213;Reactome: R-HSA-167044;Reactome: R-HSA-9026519;Reactome: R-HSA-2179392;Reactome: R-HSA-9664565;Reactome: R-HSA-512988;Reactome: R-HSA-5637810;Reactome: R-HSA-210993;Reactome: R-HSA-8853334;Reactome: R-HSA-1433557;Reactome: R-HSA-5654688;Reactome: R-HSA-5654727;Reactome: R-HSA-5654699;Reactome: R-HSA-2871809;Reactome: R-HSA-1295596;Reactome: R-HSA-1250196;Reactome: R-HSA-8851907;Reactome: R-HSA-5673001;Reactome: R-HSA-1433559;Reactome: R-HSA-9028731;Reactome: R-HSA-1963640;Reactome: R-HSA-112412;Reactome: R-HSA-354194;Reactome: R-HSA-179812;Reactome: R-HSA-8983432;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-5654726;Reactome: R-HSA-186763;Reactome: R-HSA-2428933;Reactome: R-HSA-9027284;Reactome: R-HSA-388841;Reactome: R-HSA-6807004;Reactome: R-HSA-2871796;Reactome: R-HSA-8875555;Reactome: R-HSA-8865999;Reactome: R-HSA-2029482;Reactome: R-HSA-1250347;Reactome: R-HSA-5654693;Reactome: R-HSA-5654733;Reactome: R-HSA-74749;Reactome: R-HSA-9645135;Reactome: R-HSA-109704;Reactome: R-HSA-5654704;Reactome: R-HSA-1963642	"PI-3K cascade:FGFR1";"PIP3 activates AKT signaling";"MET receptor recycling";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"PI-3K cascade:FGFR2";"Role of LAT2/NTAL/LAB on calcium mobilization";"FRS-mediated FGFR3 signaling";"Signal regulatory protein family interactions";"MET activates RAS signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR3 point mutants in cancer";"Activated NTRK2 signals through PI3K";"Signaling by FGFR4 in disease";"CD28 dependent Vav1 pathway";"Insulin receptor signalling cascade";"Signaling by FGFR2 in disease";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Activated NTRK3 signals through RAS";"Signaling by FGFR1 in disease";"PI-3K cascade:FGFR4";"FRS-mediated FGFR4 signaling";"RET signaling";"DAP12 signaling";"Clathrin-mediated endocytosis";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by cytosolic FGFR1 fusion mutants";"FLT3 Signaling";"SHC1 events in EGFR signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"NCAM signaling for neurite out-growth";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR3";"EGFR downregulation";"GAB1 signalosome";"Constitutive Signaling by Overexpressed ERBB2";"FRS-mediated FGFR2 signaling";"Interleukin receptor SHC signaling";"RHO GTPases Activate WASPs and WAVEs";"Signalling to RAS";"Activated NTRK2 signals through RAS";"EGFR Transactivation by Gastrin";"Signaling by ERBB2 KD Mutants";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Constitutive Signaling by EGFRvIII";"Tie2 Signaling";"Signaling by FGFR3 fusions in cancer";"Signaling by SCF-KIT";"SHC-mediated cascade:FGFR1";"Negative regulation of FGFR2 signaling";"SHC-mediated cascade:FGFR2";"FCERI mediated Ca+2 mobilization";"Spry regulation of FGF signaling";"SHC1 events in ERBB2 signaling";"MET activates PI3K/AKT signaling";"RAF/MAP kinase cascade";"Regulation of KIT signaling";"Activated NTRK2 signals through FRS2 and FRS3";"GRB2 events in ERBB2 signaling";"SOS-mediated signalling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"GRB2 events in EGFR signaling";"Interleukin-15 signaling";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR1 signaling";"Downstream signal transduction";"SHC-related events triggered by IGF1R";"Erythropoietin activates RAS";"Costimulation by the CD28 family";"Negative regulation of MET activity";"FCERI mediated MAPK activation";"MET activates RAP1 and RAC1";"MET activates PTPN11";"Regulation of actin dynamics for phagocytic cup formation";"SHC1 events in ERBB4 signaling";"FRS-mediated FGFR1 signaling";"Negative regulation of FGFR4 signaling";"Signal attenuation";"STAT5 Activation";"PI3K Cascade";"SHC-mediated cascade:FGFR3";"PI3K events in ERBB2 signaling"
XP_050490813.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050482246.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050480279.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050475579.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_050482120.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050496385.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050473871.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050496693.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050486840.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050478389.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050477816.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050481605.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050487440.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050477265.1	9	Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69205;Reactome: R-HSA-174411;Reactome: R-HSA-69183	"Polymerase switching";"DNA replication initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"G1/S-Specific Transcription";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand"
XP_050481643.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050476022.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050471045.1	3	KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_050475396.1	9	Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_050469532.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050472467.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050493104.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050497046.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050488726.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050489513.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050477316.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050488267.1	11	KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-7400;MetaCyc: PWY-7791;MetaCyc: PWY-5154;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2	"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050486175.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050482140.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050488875.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050484379.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050470348.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050471124.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_050480731.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050480695.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050480291.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_050492539.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050491496.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes"
XP_050476957.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050475643.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050474025.1	9	MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-7385;Reactome: R-HSA-1483166	"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA"
XP_050482103.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050472577.1	7	MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_050493946.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050489633.1	5	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050473634.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Synthesis of PC"
XP_050471330.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050475850.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_050470665.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050496989.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050478104.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050490697.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050473018.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050491852.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050489684.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050496724.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050475597.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050492693.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-168333	"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050475065.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050487806.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_050492366.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050475393.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050482516.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050480581.1	24	Reactome: R-HSA-9634635;Reactome: R-HSA-354192;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5625740;Reactome: R-HSA-392451;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5218921;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1	"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"PI3K-Akt signaling pathway";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Thermogenesis";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"Downstream TCR signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"Activation of AKT2";"VEGFR2 mediated cell proliferation";"Human immunodeficiency virus 1 infection";"RSK activation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection"
XP_050488041.1	4	KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Propanoate metabolism"
XP_050494127.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050490664.1	18	Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4	"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism"
XP_050487930.1	16	Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-164939;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-182218	"Gap junction degradation";"Formation of annular gap junctions";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation"
XP_050496509.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_050490914.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050488341.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050496616.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050480240.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050495566.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050489740.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_050474387.1	15	Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607	"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends"
XP_050491556.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050479373.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050483906.1	22	KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-7606;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5353;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-6433;MetaCyc: PWY-7053;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_050471157.1	7	MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-7456	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation"
XP_050478722.1	24	Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320	"Aggrephagy";"Recycling pathway of L1";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes"
XP_050479910.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050471433.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_050478146.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_050473987.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050486224.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050483929.1	16	Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-983168	"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050469707.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050491689.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050492529.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050473326.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_050477808.1	3	Reactome: R-HSA-75105;MetaCyc: PWY-5987;MetaCyc: PWY-5996	"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_050478195.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170670	"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway"
XP_050491157.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5789	"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_050482062.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174184	"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_050486621.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_050489139.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464	"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins"
XP_050489853.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050471522.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_050492354.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050495267.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050473217.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050477613.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-111932	"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Long-term potentiation";"HSF1-dependent transactivation";"Ion homeostasis";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB"
XP_050483650.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050475300.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-113507	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation"
XP_050471744.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050485482.1	8	Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244	"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Purine metabolism";"Long-term potentiation"
XP_050476746.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050475169.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050492535.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050478009.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050477998.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050482012.1	6	KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6983	"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis"
XP_050470717.1	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_050478731.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050482963.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050475102.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050472681.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050490304.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_050485797.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050494766.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050492324.1	12	KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Stachyose degradation"
XP_050479334.1	26	Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-5621575;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-1234158;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568	"RORA activates gene expression";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"Attenuation phase"
XP_050487281.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050484446.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050483815.1	10	Reactome: R-HSA-977225;Reactome: R-HSA-2453864;Reactome: R-HSA-3000171;Reactome: R-HSA-2453902;MetaCyc: PWY-5691;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849	"Amyloid fiber formation";"Retinoid cycle disease events";"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"Neutrophil degranulation";"Purine metabolism";"Urate conversion to allantoin III"
XP_050493291.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050472468.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050489005.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_050475307.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_050474216.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-3238698	"Neutrophil degranulation";"WNT ligand biogenesis and trafficking"
XP_050496216.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_050484516.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050474855.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050488878.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050474136.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050471527.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050484304.1	4	Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;MetaCyc: PWY-6517	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"N-acetylglucosamine degradation II"
XP_050492766.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050491849.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050490305.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_050470275.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050492494.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_050493793.1	13	Reactome: R-HSA-8964038;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665	"LDL clearance";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_050488315.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050476736.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050491382.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_050472543.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050491872.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050492845.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050472233.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050481999.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050483276.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050482781.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050491830.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050480710.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_050485768.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_050473902.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050486176.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050469948.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050472142.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050489642.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050470076.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050476413.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_050474433.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050481434.1	15	Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446	"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination"
XP_050491941.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_050482055.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050473917.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050488723.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050493806.1	14	Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5	"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_050472710.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_050496928.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050493709.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050490536.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050493255.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050470556.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_050477329.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_050470155.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050485688.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444	"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050492274.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050478062.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050496215.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_050487376.1	19	Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-8964616;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5687128;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-8950505	"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"EGFR downregulation";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"G beta:gamma signalling through CDC42";"Myogenesis";"RHO GTPases Activate Formins";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"MAPK6/MAPK4 signaling";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050492351.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050482628.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050489339.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation"
XP_050470307.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050487002.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050474896.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_050483254.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050491217.1	19	MetaCyc: PWY-6969;Reactome: R-HSA-71403;Reactome: R-HSA-70263;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-1622;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II"
XP_050480119.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050482670.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"Protein ubiquitination";"Regulation of PTEN stability and activity";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
XP_050484157.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050485617.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis"
XP_050479120.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050494062.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050481019.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050482447.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050471516.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_050487843.1	11	Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-68952	"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"DNA replication initiation"
XP_050486004.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_050481509.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050494209.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_050483358.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade"
XP_050476970.1	4	Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912	"Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_050495120.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050491877.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050493135.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050492576.1	11	Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_050485593.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_050470028.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050493599.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050477694.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050474072.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7007	"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)"
XP_050474425.1	7	KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921	"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_050469596.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050495846.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050479805.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763	"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation"
XP_050483800.1	10	Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-202424	"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Downstream TCR signaling"
XP_050482020.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050493194.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_050472833.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050472982.1	14	MetaCyc: PWY-3781;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1	"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Methylaspartate cycle";"Butanoate metabolism"
XP_050491430.1	6	Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-162594	"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle"
XP_050494236.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_050484831.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050482558.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050482021.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050480821.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050477597.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775	"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis"
XP_050476968.1	14	KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783	"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Plasmalogen degradation"
XP_050479468.1	4	KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050482379.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050480232.1	10	KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554	"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_050493805.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050477484.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048	"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Androgen biosynthesis"
XP_050470979.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050469557.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050473334.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050478733.1	3	Reactome: R-HSA-2514859;Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60	"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation";"Lysine degradation"
XP_050478046.1	8	Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050471122.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_050493158.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_050480229.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050476374.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_050487864.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050485662.1	12	Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050489915.1	182	Reactome: R-HSA-8856825;Reactome: R-HSA-937041;Reactome: R-HSA-195253;Reactome: R-HSA-1358803;Reactome: R-HSA-9014325;Reactome: R-HSA-975163;Reactome: R-HSA-8875360;Reactome: R-HSA-68949;Reactome: R-HSA-6783310;Reactome: R-HSA-8948747;Reactome: R-HSA-9613829;Reactome: R-HSA-450302;Reactome: R-HSA-2408557;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-110312;Reactome: R-HSA-156827;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-209543;Reactome: R-HSA-110314;Reactome: R-HSA-1799339;Reactome: R-HSA-182971;Reactome: R-HSA-69541;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-72649;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-9020702;Reactome: R-HSA-8876493;Reactome: R-HSA-2173795;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-69231;Reactome: R-HSA-975956;Reactome: R-HSA-8863795;Reactome: R-HSA-2559585;Reactome: R-HSA-1169408;Reactome: R-HSA-175474;Reactome: R-HSA-168927;Reactome: R-HSA-201681;Reactome: R-HSA-5607764;Reactome: R-HSA-179409;Reactome: R-HSA-2871837;Reactome: R-HSA-2672351;Reactome: R-HSA-400253;Reactome: R-HSA-2173796;Reactome: R-HSA-8939902;Reactome: R-HSA-72702;Reactome: R-HSA-5675482;Reactome: R-HSA-5689877;Reactome: R-HSA-5658442;Reactome: R-HSA-937042;Reactome: R-HSA-1236974;Reactome: R-HSA-5656169;Reactome: R-HSA-2559582;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-3322077;Reactome: R-HSA-202424;Reactome: R-HSA-9633012;Reactome: R-HSA-6781823;Reactome: R-HSA-936964;Reactome: R-HSA-5656121;Reactome: R-HSA-901032;Reactome: R-HSA-8866652;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-8866654;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-8948751;Reactome: R-HSA-2173791;Reactome: R-HSA-975110;Reactome: R-HSA-9010553;Reactome: R-HSA-5654733;Reactome: R-HSA-2122948;Reactome: R-HSA-937072;Reactome: R-HSA-917937;Reactome: R-HSA-5689901;Reactome: R-HSA-2894862;Reactome: R-HSA-5696394;Reactome: R-HSA-72689;Reactome: R-HSA-5205685;Reactome: R-HSA-445989;Reactome: R-HSA-5654732;Reactome: R-HSA-9013973;Reactome: R-HSA-68827;Reactome: R-HSA-9033241;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-168928;Reactome: R-HSA-6804757;Reactome: R-HSA-6804760;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-1236382;Reactome: R-HSA-5675221;Reactome: R-HSA-2565942;Reactome: R-HSA-8849469;Reactome: R-HSA-4641263;Reactome: R-HSA-5693565;Reactome: R-HSA-8856828;Reactome: R-HSA-5684264;Reactome: R-HSA-532668;Reactome: R-HSA-2173788;Reactome: R-HSA-69601;Reactome: R-HSA-5696395;Reactome: R-HSA-977225;Reactome: R-HSA-382556;Reactome: R-HSA-2979096;Reactome: R-HSA-69481;Reactome: R-HSA-1253288;Reactome: R-HSA-9636383;Reactome: R-HSA-168638;Reactome: R-HSA-936440;Reactome: R-HSA-2559580;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-72695;Reactome: R-HSA-3769402;Reactome: R-HSA-9646399;Reactome: R-HSA-5655862;Reactome: R-HSA-9615710;Reactome: R-HSA-5696400;Reactome: R-HSA-174490;Reactome: R-HSA-110320;Reactome: R-HSA-349425;Reactome: R-HSA-3134975;Reactome: R-HSA-205043;Reactome: R-HSA-937039;Reactome: R-HSA-209560;Reactome: R-HSA-5654727;Reactome: R-HSA-187577;Reactome: R-HSA-5693607;Reactome: R-HSA-1295596;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-5654726;Reactome: R-HSA-162588;Reactome: R-HSA-5610785;Reactome: R-HSA-975957;Reactome: R-HSA-5685942;Reactome: R-HSA-6791226;Reactome: R-HSA-912631;Reactome: R-HSA-174048;Reactome: R-HSA-72706;Reactome: R-HSA-5689896;Reactome: R-HSA-9637628;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-156902;Reactome: R-HSA-174084;Reactome: R-HSA-2691232;Reactome: R-HSA-2122947;Reactome: R-HSA-450321;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-6807004;Reactome: R-HSA-8852276;Reactome: R-HSA-9645460;Reactome: R-HSA-4641258;Reactome: R-HSA-917729;Reactome: R-HSA-6782135;Reactome: R-HSA-192823;Reactome: R-HSA-5668541;Reactome: R-HSA-6781827;Reactome: R-HSA-5696397;Reactome: R-HSA-72764;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-3785653	"Cargo recognition for clathrin-mediated endocytosis";"IKK complex recruitment mediated by RIP1";"Degradation of beta-catenin by the destruction complex";"Downregulation of ERBB2:ERBB3 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Orc1 removal from chromatin";"Fanconi Anemia Pathway";"Regulation of PTEN localization";"Chaperone Mediated Autophagy";"activated TAK1 mediates p38 MAPK activation";"Selenocysteine synthesis";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"UCH proteinases";"Translesion synthesis by REV1";"L13a-mediated translational silencing of Ceruloplasmin expression";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"p75NTR recruits signalling complexes";"Recognition of DNA damage by PCNA-containing replication complex";"SRP-dependent cotranslational protein targeting to membrane";"EGFR downregulation";"Stabilization of p53";"Negative regulation of NOTCH4 signaling";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Translation initiation complex formation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"Interleukin-1 signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Cyclin D associated events in G1";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Downregulation of ERBB2 signaling";"Oncogene Induced Senescence";"ISG15 antiviral mechanism";"Assembly Of The HIV Virion";"TICAM1, RIP1-mediated IKK complex recruitment";"TCF dependent signaling in response to WNT";"CLEC7A (Dectin-1) signaling";"APC-Cdc20 mediated degradation of Nek2A";"FCERI mediated NF-kB activation";"Stimuli-sensing channels";"Circadian Clock";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of RUNX2 expression and activity";"Ribosomal scanning and start codon recognition";"Regulation of necroptotic cell death";"Josephin domain DUBs";"Regulation of RAS by GAPs";"IRAK2 mediated activation of TAK1 complex";"ER-Phagosome pathway";"Termination of translesion DNA synthesis";"Senescence-Associated Secretory Phenotype (SASP)";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Glycogen synthesis";"Downstream TCR signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of TC-NER Pre-Incision Complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Translesion synthesis by POLI";"ER Quality Control Compartment (ERQC)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN stability and activity";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of FGFR4 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Iron uptake and transport";"Metalloprotease DUBs";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"DNA Damage Recognition in GG-NER";"Formation of a pool of free 40S subunits";"Pink/Parkin Mediated Mitophagy";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Negative regulation of FGFR3 signaling";"TICAM1-dependent activation of IRF3/IRF7";"CDT1 association with the CDC6:ORC:origin complex";"Peroxisomal protein import";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Methylation";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of MAPK pathway";"Regulation of PLK1 Activity at G2/M Transition";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of FZD by ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Clathrin-mediated endocytosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downregulation of TGF-beta receptor signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Formation of Incision Complex in GG-NER";"Amyloid fiber formation";"ABC-family proteins mediated transport";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"G2/M Checkpoints";"Downregulation of ERBB4 signaling";"Prevention of phagosomal-lysosomal fusion";"NOD1/2 Signaling Pathway";"Negative regulators of DDX58/IFIH1 signaling";"Oxidative Stress Induced Senescence";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of the ternary complex, and subsequently, the 43S complex";"Deactivation of the beta-catenin transactivating complex";"Aggrephagy";"Translesion synthesis by POLK";"Late endosomal microautophagy";"Dual Incision in GG-NER";"Membrane binding and targetting of GAG proteins";"Translesion Synthesis by POLH";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of innate immune responses to cytosolic DNA";"NRIF signals cell death from the nucleus";"IRAK1 recruits IKK complex";"NF-kB is activated and signals survival";"Negative regulation of FGFR2 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Processing of DNA double-strand break ends";"Spry regulation of FGF signaling";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of FGFR1 signaling";"Budding and maturation of HIV virion";"GLI3 is processed to GLI3R by the proteasome";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"HDR through Homologous Recombination (HRR)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of signaling by CBL";"APC/C:Cdc20 mediated degradation of Cyclin B";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ovarian tumor domain proteases";"Modulation by Mtb of host immune system";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Peptide chain elongation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Negative regulation of MET activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Alpha-protein kinase 1 signaling pathway";"Degradation of DVL";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Dual incision in TC-NER";"Viral mRNA Translation";"TNFR2 non-canonical NF-kB pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Eukaryotic Translation Termination";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myoclonic epilepsy of Lafora"
XP_050472115.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050489194.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050480253.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050487785.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050480238.1	10	MetaCyc: PWY-6361;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6372	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_050482761.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050469454.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050475894.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050475526.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050475205.1	9	KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Thermogenesis"
XP_050489186.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050475035.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050480096.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050495129.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism"
XP_050487922.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_050492345.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050491933.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050494981.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_050473059.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050484767.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050479900.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050477236.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050477493.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-416482	"G alpha (z) signalling events";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G alpha (12/13) signalling events"
XP_050472157.1	16	Reactome: R-HSA-975871;Reactome: R-HSA-975155;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-5602498;Reactome: R-HSA-1810476;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-9020702;Reactome: R-HSA-166058;Reactome: R-HSA-1236974;Reactome: R-HSA-209543;Reactome: R-HSA-3134963	"MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"Interleukin-1 signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"ER-Phagosome pathway";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"
XP_050489054.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050490027.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050482754.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050484270.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050483848.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050481337.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050477542.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_050491685.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation"
XP_050480065.1	15	Reactome: R-HSA-9665251;Reactome: R-HSA-9652282;Reactome: R-HSA-9665245;Reactome: R-HSA-8863795;Reactome: R-HSA-1236382;Reactome: R-HSA-9665250;Reactome: R-HSA-9665247;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-1227986;Reactome: R-HSA-9665233;Reactome: R-HSA-9665244;Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-9634285	"Resistance of ERBB2 KD mutants to lapatinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to tesevatinib";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by Overexpressed ERBB2"
XP_050471485.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050472807.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050472328.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050491550.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis"
XP_050486246.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050472245.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050490266.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050475041.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050488932.1	52	Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-167287;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape"
XP_050482785.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050478421.1	6	MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-5651;MetaCyc: PWY-6309	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_050492701.1	12	KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5856	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_050472937.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050481676.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050491071.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050482569.1	11	Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-8939236	"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_050486211.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050482457.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562	"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)"
XP_050474222.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050493131.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050477945.1	3	Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050496424.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050493702.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050485451.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050485579.1	3	KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle"
XP_050469904.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050488395.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050488330.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050475823.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_050488276.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050479885.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050471066.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050469373.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050487265.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050491643.1	7	KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Thiamine metabolism"
XP_050494424.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050483434.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_050493590.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_050490747.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_050483283.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050493032.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050487541.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_050490975.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050496929.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050482627.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050469668.1	30	Reactome: R-HSA-8948751;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-389513;Reactome: R-HSA-1358803;Reactome: R-HSA-9634638;Reactome: R-HSA-111447;Reactome: R-HSA-9614399;Reactome: R-HSA-392451;Reactome: R-HSA-6804758;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-198323;Reactome: R-HSA-198693;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69656;Reactome: R-HSA-8876198;Reactome: R-HSA-8941332;Reactome: R-HSA-211163;Reactome: R-HSA-199418;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804759	"Regulation of PTEN stability and activity";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Cyclin E associated events during G1/S transition";"Regulation of TP53 Degradation";"Thermogenesis";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"CTLA4 inhibitory signaling";"Downregulation of ERBB2:ERBB3 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Activation of BAD and translocation to mitochondria";"Regulation of localization of FOXO transcription factors";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Activity through Acetylation";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"AKT phosphorylates targets in the cytosol";"AKT phosphorylates targets in the nucleus";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Cyclin A:Cdk2-associated events at S phase entry";"RAB GEFs exchange GTP for GDP on RABs";"RUNX2 regulates genes involved in cell migration";"AKT-mediated inactivation of FOXO1A";"Negative regulation of the PI3K/AKT network";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Association with Co-factors"
XP_050476591.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_050481608.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050496684.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050470409.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050481874.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050493387.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050481934.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050491967.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050493780.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_050472091.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_050479284.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050496954.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_050491400.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050487086.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050473239.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050496829.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_050480617.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050477126.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_050488252.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050491138.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050486349.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050487724.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_050471223.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050475885.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050484815.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400	"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_050477707.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050485915.1	2	Reactome: R-HSA-71384;KEGG: 00030+1.1.1.47	"Ethanol oxidation";"Pentose phosphate pathway"
XP_050490222.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050484231.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050484391.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050471512.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050475902.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_050471524.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050486979.1	13	KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-5497;MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757	"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines"
XP_050471997.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050490442.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050470692.1	33	Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_050485703.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport"
XP_050477548.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050484867.1	3	Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_050483454.1	10	MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2	"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism"
XP_050482576.1	3	Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_050496483.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050474891.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050469890.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases"
XP_050485030.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050488313.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050474456.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_050476100.1	16	Reactome: R-HSA-2046105;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-2046106;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041	"Linoleic acid (LA) metabolism";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"alpha-linolenic acid (ALA) metabolism";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_050478592.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050489814.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050479129.1	4	Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590	"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"NIK-->noncanonical NF-kB signaling"
XP_050492315.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050492048.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3	"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Glycerophospholipid metabolism"
XP_050475294.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050476251.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050491308.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050471385.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_050491751.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050487310.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_050488577.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050493608.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050476491.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050476103.1	16	MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-2046105;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-2046106	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Linoleic acid (LA) metabolism";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"alpha-linolenic acid (ALA) metabolism"
XP_050486288.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050469700.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050480672.1	4	Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism"
XP_050483436.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050480324.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050470070.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050486969.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050477469.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050481560.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_050474640.1	2	Reactome: R-HSA-6785807;Reactome: R-HSA-2173796	"Interleukin-4 and Interleukin-13 signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_050489902.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050483057.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_050480998.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050482865.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050491473.1	12	MetaCyc: PWY-5872;Reactome: R-HSA-1268020;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5855;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39	"Ubiquinol-10 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_050472128.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_050483404.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050485415.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050492322.1	12	MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-3801	"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)"
XP_050476320.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050473796.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_050489539.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_050488734.1	57	Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084	"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_050482572.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050482997.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050489881.1	57	Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780	"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome"
XP_050484016.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_050481229.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050486894.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
XP_050480613.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050480942.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050469531.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050485412.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493256.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050493636.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_050472798.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050482467.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050475118.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050490957.1	11	Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-72163;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796	"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"mRNA Splicing - Major Pathway";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_050489463.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050491077.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050481966.1	8	MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168	"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_050489821.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050490406.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050470228.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_050470511.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_050480318.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050480651.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050489536.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_050496464.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050491238.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214	"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_050472780.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050490446.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050485605.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050494982.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_050489481.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050480250.1	10	MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system"
XP_050482671.1	5	Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Regulation of PTEN stability and activity";"Protein ubiquitination";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_050490035.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050477233.1	8	KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7117	"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_050476761.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050489526.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050480078.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050474676.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-2467813;Reactome: R-HSA-380259;Reactome: R-HSA-9648025;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids";"Loss of Nlp from mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_050473679.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050470879.1	14	MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3841;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181	"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I";"Folate transformations II (plants)";"Methane metabolism";"Folate polyglutamylation";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Cyanoamino acid metabolism";"Photorespiration "
XP_050471913.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050482228.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050472938.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050474004.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_050469884.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050479455.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-5658442	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"Regulation of RAS by GAPs"
XP_050472208.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050472223.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050497043.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_050496108.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050485437.1	3	Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669	"Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_050482762.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050481465.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050482237.1	3	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_050470790.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050493626.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050470865.1	9	Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway"
XP_050476493.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050475165.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050472224.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050492916.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050491861.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050482951.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050471700.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism"
XP_050489556.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050483456.1	10	MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2	"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism"
XP_050489338.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins"
XP_050493228.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050469636.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050472877.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050484982.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050496174.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_050482238.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050480254.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050483994.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050495635.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050471340.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556	"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport"
XP_050471394.1	6	MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;Reactome: R-HSA-446199	"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_050470670.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050481832.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050486341.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050492111.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_050482150.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050494172.1	4	MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_050473973.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050478395.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050493378.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050477547.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050489448.1	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_050488214.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050477328.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling"
XP_050492997.1	12	Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction";"Purine metabolism"
XP_050479980.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050477775.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050489860.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050486205.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050487200.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050471508.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050492872.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_050488365.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050479590.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050490809.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050477865.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050478959.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050484678.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_050483280.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050489042.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68827	"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_050485805.1	40	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167172	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome"
XP_050487948.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695	"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation"
XP_050474840.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050483657.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050486002.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_050484717.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050483992.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050470673.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050484989.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_050484891.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_050476237.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050486857.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050483002.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050469672.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050482823.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050485496.1	8	Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244	"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Long-term potentiation"
XP_050493507.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_050494344.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_050492386.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852	"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Macroautophagy"
XP_050477465.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050474013.1	5	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050481477.1	16	Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558	"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"G alpha (q) signalling events";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_050471008.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050471123.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_050470219.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050494770.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050491711.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050485619.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050476889.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050476039.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050496588.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050477457.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050491237.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_050492316.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050481537.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050478981.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050487018.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050489681.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446	"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination"
XP_050491752.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050490223.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050479836.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050472935.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050472748.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050476679.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050483508.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050493579.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_050496261.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050489378.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_050492999.1	12	MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4	"Selenate reduction";"Selenocompound metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Purine metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism"
XP_050477267.1	9	Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69183	"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand"
XP_050493495.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050491631.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050477809.1	3	MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987	"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis"
XP_050482850.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_050489776.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050469969.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050475960.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050482230.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050483167.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050470621.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050470369.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-8950505	"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050496214.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211	"Estrogen-dependent gene expression";"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling"
XP_050474078.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050482797.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050492995.1	12	KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25	"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Selenate reduction";"Sulfite oxidation III";"Sulfur metabolism";"Purine metabolism"
XP_050470864.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050473332.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050484635.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050485380.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050470721.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050476861.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050493376.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050487622.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050478193.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050480914.1	12	KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection";"Rho GTPase cycle";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway"
XP_050474345.1	4	Reactome: R-HSA-72203;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-72163	"Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins";"HCMV Late Events";"mRNA Splicing - Major Pathway"
XP_050490297.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_050489449.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041	"Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle"
XP_050472995.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050480842.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050488574.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_050470999.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_050491707.1	4	MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662	"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism"
XP_050473847.1	13	KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II"
XP_050493397.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050475951.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050483435.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050496810.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050472744.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050497129.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050475007.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_050491701.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_050484245.1	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684	"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state"
XP_050484390.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050486207.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050478187.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_050473437.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)"
XP_050470602.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050471265.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050473923.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050484683.1	6	MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis"
XP_050485316.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5	"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_050482422.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050473846.1	13	Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52	"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series"
XP_050476484.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050471018.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050476709.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050479847.1	11	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection"
XP_050475854.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation"
XP_050482443.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050475466.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050493456.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050477084.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation"
XP_050478056.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation"
XP_050483905.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050489475.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050485486.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Long-term potentiation";"Purine metabolism";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050477909.1	33	Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-112382;Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-69231;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76042	"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"Formation of RNA Pol II elongation complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050470068.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050482061.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174178	"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_050490504.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050482744.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050473829.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_050496734.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050492333.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050471868.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_050484253.1	7	Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838	"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO"
XP_050494253.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050485166.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050472113.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050486429.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050493289.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050490781.1	18	Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-112382	"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex"
XP_050496430.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050484915.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_050471007.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050480095.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050480794.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050494980.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_050490023.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050472663.1	17	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-6790901	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol"
XP_050494061.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_050494164.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_050489145.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050481180.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050492960.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050486206.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050482118.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050481659.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050487571.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050486622.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_050481472.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050474098.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050493432.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050494652.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_050471082.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050482403.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050490494.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050493541.1	14	MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051	"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Anandamide biosynthesis I"
XP_050475194.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation"
XP_050479896.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050491409.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050485526.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_050476376.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050481967.1	6	Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_050469676.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_050496071.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050484194.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050491582.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050482565.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-5685938	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)"
XP_050473782.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050491222.1	29	Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823	"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050477288.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_050472898.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050474848.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_050488211.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_050477601.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946	"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants"
XP_050470578.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050474505.1	10	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2160916	"Galactose metabolism";"Other glycan degradation";"HS-GAG degradation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation"
XP_050481211.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050473013.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_050493133.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050479283.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050488378.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050496350.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_050477817.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_050484230.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050496968.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050477518.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050485998.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050488250.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050497030.1	14	MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5103;Reactome: R-HSA-70895;MetaCyc: PWY-5076;MetaCyc: PWY-5057;MetaCyc: PWY-7767;MetaCyc: PWY-5104;MetaCyc: PWY-5101;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42	"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis III";"Branched-chain amino acid catabolism";"L-leucine degradation III";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis II";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation"
XP_050477799.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_050478632.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050487472.1	8	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083633	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_050489056.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050477679.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_050493176.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050491109.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556	"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport"
XP_050489023.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050489755.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050484487.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050479355.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050470593.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050482567.1	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_050484216.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050492873.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_050469845.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050487827.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050480305.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_050473821.1	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
XP_050477654.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050496484.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050483967.1	4	KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism"
XP_050472561.1	3	KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_050480508.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050494271.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_050490450.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050489329.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050471120.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_050495476.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
XP_050486769.1	6	Reactome: R-HSA-5620916;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-6811438	"VxPx cargo-targeting to cilium";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intra-Golgi traffic"
XP_050489961.1	10	Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-917729	"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050481757.1	14	Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Polymerase switching";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_050481395.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050471261.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050488319.1	9	Reactome: R-HSA-3371599;MetaCyc: PWY-8086;Reactome: R-HSA-196780;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142	"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050485498.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982	"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050485748.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050479428.1	30	Reactome: R-HSA-5610780;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-2894862;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-2644607;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-9604323	"Degradation of GLI1 by the proteasome";"Circadian Clock";"Iron uptake and transport";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"Prolactin receptor signaling";"Negative regulation of NOTCH4 signaling"
XP_050496702.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-8856828	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis"
XP_050471435.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050493781.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_050485119.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_050474838.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050482798.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050478209.1	16	Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-180585	"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of HIV elongation";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G"
XP_050472707.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050490796.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050487534.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_050492658.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050470245.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"Viral mRNA Translation";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_050487840.1	11	Reactome: R-HSA-68952;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-110314	"DNA replication initiation";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050477741.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050483083.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616	"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication"
XP_050478872.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050470231.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_050491581.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050496617.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050490646.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050493733.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050471240.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828	"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis"
XP_050492689.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_050496924.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050479984.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050493911.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050488786.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050487268.1	5	Reactome: R-HSA-70895;Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4	"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation"
XP_050481471.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050492688.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050472816.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_050475596.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050481166.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050492367.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050489508.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050485028.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050488722.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050477446.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_050472586.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050471254.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_050487439.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050470932.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_050484689.1	6	Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050477782.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050475247.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277	"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex"
XP_050497045.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050477856.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050483654.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050489141.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464	"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins"
XP_050487137.1	11	KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-5695;MetaCyc: PWY-6607;MetaCyc: PWY-5381;KEGG: 00760+3.1.3.5	"Pyrimidine metabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Purine metabolism";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_050484447.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050490920.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050478508.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_050475310.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050493754.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050494175.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_050485772.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_050475832.1	10	MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-7344	"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis"
XP_050469468.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050483493.1	13	MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_050470278.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050483577.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050470046.1	8	KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;Reactome: R-HSA-6798695;MetaCyc: PWY-6556;MetaCyc: PWY-7193;MetaCyc: PWY-7181;MetaCyc: PWY-7199	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage"
XP_050478392.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050480091.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050473339.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050480809.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050470006.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050471090.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050473627.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_050482052.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050478509.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_050475580.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_050490445.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050489949.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050481873.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050475962.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050490303.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_050478066.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050473419.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050485172.1	7	Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70268	"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism"
XP_050481464.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050485516.1	13	Reactome: R-HSA-1442490;Reactome: R-HSA-216083;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919	"Collagen degradation";"Integrin cell surface interactions";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"NCAM1 interactions";"Anchoring fibril formation";"Collagen chain trimerization";"Crosslinking of collagen fibrils"
XP_050488787.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050470770.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050490444.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050496838.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050485506.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050485597.1	52	Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-674695;Reactome: R-HSA-76066;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-76042	"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050480801.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050491909.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17	"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism"
XP_050485933.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050480042.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050494325.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050484465.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism"
XP_050489060.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764	"Degradation of DVL";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling"
XP_050481225.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050496962.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050487849.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050492758.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050479069.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050496201.1	5	KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Glutathione metabolism";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_050471568.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050476590.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_050479935.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050469987.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050481875.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050482386.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050481604.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050484399.1	12	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050490134.1	9	Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3642279;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356	"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_050473787.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050492769.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050470324.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050473520.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-6784531	"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus"
XP_050482023.1	3	MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141	"Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_050494762.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050480867.1	9	MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Phosphatidylinositol signaling system"
XP_050470011.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854	"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly"
XP_050493646.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050484163.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050481650.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050496494.1	7	KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625	"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_050471745.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050469723.1	5	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Neutrophil degranulation"
XP_050481040.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050490956.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_050492717.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050496134.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050482566.1	11	Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482	"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation"
XP_050489816.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050486166.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050491459.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050472784.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050484885.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424	"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling"
XP_050484895.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814	"Collagen degradation";"MET activates PTK2 signaling";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes"
XP_050477354.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050482242.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050490909.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_050494337.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050481978.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Neutrophil degranulation";"Clathrin-mediated endocytosis"
XP_050477820.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050486595.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050488090.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050488040.1	4	Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27	"Branched-chain amino acid catabolism";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation"
XP_050479240.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050470179.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050495269.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_050473901.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050469674.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050476010.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050485293.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050473336.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050477020.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050477615.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952	"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions"
XP_050477169.1	22	MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-7602;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_050476196.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050497078.1	6	Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693	"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling"
XP_050496428.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050492455.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_050489037.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050472641.1	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050489946.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710	"Chaperone Mediated Autophagy";"Aggrephagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy"
XP_050470684.1	5	KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_050474777.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050483649.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050474070.1	20	Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6	"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism"
XP_050470161.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050486762.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050474899.1	9	Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476	"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"G alpha (q) signalling events"
XP_050471400.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050485875.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050489204.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050481305.1	42	Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-2559582;Reactome: R-HSA-427389;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-73728;Reactome: R-HSA-212300;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-5250924;Reactome: R-HSA-5334118;Reactome: R-HSA-5617472;Reactome: R-HSA-110329;Reactome: R-HSA-3214847;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-3214815;Reactome: R-HSA-110328;Reactome: R-HSA-977225;Reactome: R-HSA-5625886;Reactome: R-HSA-4551638;Reactome: R-HSA-912446;Reactome: R-HSA-2299718	"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"Senescence-Associated Secretory Phenotype (SASP)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Opening";"PRC2 methylates histones and DNA";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"Meiotic synapsis";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"B-WICH complex positively regulates rRNA expression";"DNA methylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged pyrimidine";"HATs acetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"RMTs methylate histone arginines";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SUMOylation of chromatin organization proteins";"Meiotic recombination";"Condensation of Prophase Chromosomes"
XP_050494032.1	6	Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16	"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050469628.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050492963.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050491209.1	22	Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"RAF activation";"RHO GTPases Activate Formins"
XP_050485651.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_050491892.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_050473970.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050490601.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_050488725.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050474830.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050483475.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050484452.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_050483787.1	10	Reactome: R-HSA-2453864;Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-6798695;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;MetaCyc: PWY-5691	"Retinoid cycle disease events";"Amyloid fiber formation";"Purine metabolism";"Urate conversion to allantoin III";"Neutrophil degranulation";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Urate conversion to allantoin I"
XP_050473647.1	15	Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176412	"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C"
XP_050470518.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_050476572.1	14	KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8053	"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PE";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II"
XP_050470387.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050491976.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050481994.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_050473903.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050478864.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_050478145.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_050469466.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050474270.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050475578.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_050484540.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050479595.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050497122.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050481557.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_050478114.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_050483975.1	7	KEGG: 00072+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4	"Synthesis and degradation of ketone bodies";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Peroxisomal protein import";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Butanoate metabolism"
XP_050492247.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050474752.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050494272.1	3	KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_050482688.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_050490562.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050482665.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_050494008.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050477094.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_050477177.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_050493126.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050472192.1	12	MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13	"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Glutathione-mediated detoxification II";"Selenocompound metabolism"
XP_050473567.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050492113.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050474520.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_050470822.1	8	Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823	"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex"
XP_050487718.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_050480304.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_050480853.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050486676.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050471362.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356	"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_050493152.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050478719.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_050469630.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050488942.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050471809.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050480348.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050478101.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050477450.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050475574.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050475365.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_050493716.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050481171.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050491905.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_050485531.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050474733.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050486400.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_050479464.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-2586552	"Prolactin receptor signaling";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin"
XP_050479846.1	11	Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1	"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"p38MAPK events";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Oxidative Stress Induced Senescence";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway"
XP_050495203.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7082	"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_050491897.1	6	MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Caprolactam degradation"
XP_050487184.1	8	MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-3581;KEGG: 00350+1.14.16.2;KEGG: 00790+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-5049	"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis I";"Tyrosine metabolism";"Folate biosynthesis";"Catecholamine biosynthesis";"Rosmarinic acid biosynthesis II"
XP_050470800.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050479403.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050475815.1	5	MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050492767.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050490243.1	24	Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-418597	"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events"
XP_050470575.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050476971.1	4	Reactome: R-HSA-2162123;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Neutrophil degranulation"
XP_050474351.1	4	Reactome: R-HSA-72203;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-72163	"Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins";"HCMV Late Events";"mRNA Splicing - Major Pathway"
XP_050476156.1	4	Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_050487717.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_050484017.1	6	Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_050481959.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050496232.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_050480231.1	10	KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050485800.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050479591.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050484792.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
XP_050477448.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_050485082.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050476021.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050473632.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6814122	"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050482160.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050473687.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050491072.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050492395.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_050493316.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050497113.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050470759.1	17	Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-8853884	"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX"
XP_050488290.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_050471298.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-1362277;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-69017;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Transcription of E2F targets under negative control by DREAM complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress"
XP_050477543.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_050482056.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050485492.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-447038	"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions"
XP_050482401.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050471867.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_050481209.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050487781.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050495412.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050480477.1	5	MetaCyc: PWY-7782;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_050475591.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050496835.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050494163.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050470185.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050492794.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_050487605.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050489376.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_050494765.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050473848.1	13	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation"
XP_050477402.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050496431.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050489015.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050496410.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681	"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling"
XP_050474494.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050486970.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050485040.1	3	Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067	"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_050477680.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_050496348.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_050486076.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050480275.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050491731.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050488353.1	5	KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109	"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis"
XP_050476380.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_050480307.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_050473948.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050489771.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050478292.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050470062.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_050486573.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050479838.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I"
XP_050482277.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050477663.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050477152.1	17	MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6609;MetaCyc: PWY-6627	"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Neutrophil degranulation";"Purine catabolism";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Salinosporamide A biosynthesis"
XP_050479383.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050495091.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050470873.1	9	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050479580.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050485661.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050479927.1	24	KEGG: 04151+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5625740;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218921;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"Relaxin signaling pathway";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"Downstream TCR signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Activation of AKT2";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"Human immunodeficiency virus 1 infection";"RSK activation";"VEGFR2 mediated cell proliferation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection"
XP_050491871.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050476682.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
XP_050496383.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050493241.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050486200.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050493027.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050488956.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_050486963.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050491260.1	3	KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_050480740.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050471347.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050475008.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_050482571.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050471952.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-611105	"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport"
XP_050491505.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_050476160.1	5	Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050483690.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684	"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state"
XP_050496984.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050488626.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050476106.1	16	Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6433;Reactome: R-HSA-2046106;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-2046105;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"alpha-linolenic acid (ALA) metabolism";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Linoleic acid (LA) metabolism";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050489421.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050496717.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050474397.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_050486048.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050484209.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050487712.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events"
XP_050491606.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050481758.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-110314	"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Polymerase switching";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050479159.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_050497079.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001	"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade"
XP_050490282.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050479811.1	13	Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-4086398	"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway"
XP_050474914.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050493024.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050491934.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050493298.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050488643.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes"
XP_050490448.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050484627.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050496366.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472	"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050474776.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050486567.1	52	Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8948751	"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Degradation of DVL";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Regulation of PTEN stability and activity"
XP_050484320.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_050481479.1	16	Reactome: R-HSA-114604;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-512988	"GPVI-mediated activation cascade";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"RET signaling";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_050487216.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050473757.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050480482.1	5	Reactome: R-HSA-9033500;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Peroxisomal protein import"
XP_050470731.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050474918.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050492525.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050492914.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050493652.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050486457.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050493782.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_050482186.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050480478.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050472522.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050473045.1	20	Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411	"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere"
XP_050483525.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_050472724.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050491113.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050478808.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050486055.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050496811.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_050489160.1	25	Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-381771;Reactome: R-HSA-418597;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-163359	"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (z) signalling events";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation"
XP_050482001.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_050486430.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050488981.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050493601.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691;Reactome: R-HSA-6785807	"T cell receptor signaling pathway";"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling"
XP_050474272.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050481044.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050470892.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050469751.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050478693.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-176408	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase"
XP_050493514.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050487253.1	5	Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;MetaCyc: PWY-7511	"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Protein ubiquitination"
XP_050491981.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_050487736.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_050493578.1	14	MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416	"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_050486405.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_050471758.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
XP_050476109.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050476791.1	32	Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-77075	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050487987.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050473823.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050485543.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_050480336.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050470004.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_050493308.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050489009.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050471414.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050482149.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050478766.1	8	MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism"
XP_050492105.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050484826.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050488240.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_050481441.1	4	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505	"Cristae formation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050487749.1	52	Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-749476	"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050488519.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050476839.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050469735.1	1	Reactome: R-HSA-156581	"Methylation"
XP_050477569.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050479372.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050475740.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050484668.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_050478796.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050475376.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050483000.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050472491.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050480131.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050491129.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050474093.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050486618.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_050473631.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243	"Synthesis of PC";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050476953.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050481097.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050485934.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050477598.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946	"Ion homeostasis";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants"
XP_050470311.1	3	Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050471894.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050480881.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_050488569.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050482556.1	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_050480952.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050490071.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050491499.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_050487519.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"HDACs deacetylate histones";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity"
XP_050495041.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_050481396.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050482849.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_050496354.1	12	KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13	"Methane metabolism";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway"
XP_050478391.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050478546.1	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_050469408.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_050487464.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050489490.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050487172.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050496391.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050496626.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050477622.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066	"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Trafficking of AMPA receptors";"Long-term potentiation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_050487256.1	29	Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565	"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Translesion synthesis by REV1";"Dual incision in TC-NER";"HSF1 activation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_050472462.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050489496.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050487389.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050494205.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_050470091.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_050481602.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050477356.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050487071.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_050474482.1	7	KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Inositol phosphate metabolism";"Phytate degradation I";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_050478063.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050487931.1	16	Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-164939;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-177504	"Formation of annular gap junctions";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling"
XP_050489894.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050473774.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050470406.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050479678.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050496919.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050487701.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050472241.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050481880.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050473261.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050480382.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423	"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Chylomicron assembly";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"LDL remodeling";"Clathrin-mediated endocytosis";"VLDL clearance";"Platelet sensitization by LDL";"LDL clearance";"VLDL assembly"
XP_050476495.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050489960.1	10	Reactome: R-HSA-8856825;Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-432720	"Cargo recognition for clathrin-mediated endocytosis";"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis"
XP_050492772.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050481648.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050479282.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050487125.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050475964.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050482315.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050486682.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050491210.1	22	Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5358752;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358751	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"T41 mutants of beta-catenin aren't phosphorylated";"RAF activation";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated"
XP_050474381.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050488170.1	10	Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022692	"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity"
XP_050473384.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050489021.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050475888.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050476723.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050485303.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050485488.1	12	Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;MetaCyc: PWY-7221	"Trafficking of AMPA receptors";"Long-term potentiation";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis"
XP_050469820.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050478728.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050486198.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050482048.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_050480721.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1"
XP_050485497.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050480776.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050478654.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_050473754.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050492318.1	12	MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-173599;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9	"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism"
XP_050472488.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050484836.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050485862.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050479160.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050492407.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_050491170.1	31	Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWY-7723;MetaCyc: PWY-5142;MetaCyc: PWY-4381;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-5966-1;MetaCyc: PWY-8049;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-6113;Reactome: R-HSA-75105;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6519;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWYG-321;MetaCyc: PWY-6799;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-7663	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Biotin metabolism";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Gondoate biosynthesis (anaerobic)"
XP_050491297.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050493347.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050473345.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050473557.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_050485070.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050475394.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050472303.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050480244.1	10	MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_050470789.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050490984.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050492515.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050493053.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050478400.1	10	MetaCyc: PWY-7921;Reactome: R-HSA-162699;MetaCyc: PWY-7979;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;Reactome: R-HSA-913709;MetaCyc: PWY-7661;KEGG: 00510+2.4.1.83	"Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation of mucins";"Protein N-glycosylation (Haloferax volcanii)";"N-Glycan biosynthesis"
XP_050489389.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050481182.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050491578.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050487317.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050477587.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000	"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Long-term potentiation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation"
XP_050473681.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050477022.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050471219.1	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012	"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050487916.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_050485452.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050488279.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050491500.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex"
XP_050491706.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_050496963.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050493686.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_050481820.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050489032.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050478231.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050480109.1	5	MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892	"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
XP_050489328.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_050484995.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_050475373.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050474796.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050496758.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050489110.1	6	KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181	"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism"
XP_050490379.1	6	MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22	"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism"
XP_050479933.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050482412.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050492493.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050481998.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_050485613.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_050482622.1	7	KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16	"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_050476054.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050473001.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050494059.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_050485736.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050483287.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050482007.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050469878.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050496630.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050490591.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050476217.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050490135.1	9	Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"UCH proteinases"
XP_050472209.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050484623.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050488813.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050471609.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_050479298.1	26	Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9609690	"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Kinesins";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events"
XP_050474398.1	3	Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_050472257.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050479835.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050473951.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050471845.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050496944.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_050487406.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050472704.1	14	Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110314	"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050486795.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_050485936.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050487474.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050471468.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050481671.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050490126.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050482207.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_050487634.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050469473.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_050475817.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape"
XP_050481476.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391	"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"RET signaling";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"G alpha (q) signalling events";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling"
XP_050470063.1	4	Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75	"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis"
XP_050475630.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050488732.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050481393.1	5	Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-111458;MetaCyc: PWY-4361	"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Methionine salvage pathway";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050489482.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050477401.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_050472078.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_050490499.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050471083.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050474799.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050471069.1	7	MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824	"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis"
XP_050488541.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050474290.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050490287.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050492630.1	6	Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722	"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex"
XP_050470416.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050485686.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050476104.1	16	MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;Reactome: R-HSA-2046106;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-2046105	"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"alpha-linolenic acid (ALA) metabolism";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Linoleic acid (LA) metabolism"
XP_050494379.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050483181.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050473308.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050479181.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050486358.1	1	Reactome: R-HSA-8963684	"Tyrosine catabolism"
XP_050471279.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050474632.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_050477083.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_050484378.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050490735.1	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7176	"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis"
XP_050479872.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050472320.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050476993.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050486771.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050480454.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050490242.1	24	Reactome: R-HSA-456926;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-418217	"Thrombin signalling through proteinase activated receptors (PARs)";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta"
XP_050478707.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050483533.1	17	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050490471.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050482998.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050487735.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050495124.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_050469823.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050485024.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050481759.1	14	Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110314	"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Polymerase switching";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050483010.1	5	MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_050480618.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050487426.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050496854.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_050484920.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050487640.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050484183.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050480627.1	4	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300	"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA"
XP_050487455.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050478294.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050488874.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050478810.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050470116.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050480735.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050469799.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050477035.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050470038.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050474426.1	7	Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_050479051.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050491236.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461	"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation"
XP_050477924.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050490726.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050479609.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050482625.1	7	KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22	"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_050492522.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050482163.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050470227.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_050475320.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050487482.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_050483407.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050473430.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol"
XP_050489109.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050484938.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_050480975.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050487989.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050484846.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_050477575.1	17	Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050495092.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050483327.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948	"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants"
XP_050486204.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050491469.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050473278.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050476712.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050480923.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050476994.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050482649.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050492843.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050479093.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_050475498.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050472951.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050477414.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050482407.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050481176.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050484511.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050479604.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050474558.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050491312.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
XP_050480676.1	24	Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-202424;Reactome: R-HSA-2730905;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218921;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5625740;Reactome: R-HSA-392451	"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"Downstream TCR signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"Human cytomegalovirus infection";"VEGFR2 mediated cell proliferation";"Human immunodeficiency virus 1 infection";"RSK activation";"FCERI mediated NF-kB activation";"Human papillomavirus infection";"Activation of AKT2";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma"
XP_050494329.1	3	Reactome: R-HSA-111465;Reactome: R-HSA-1660499;KEGG: 04660+2.7.10.2	"Apoptotic cleavage of cellular proteins";"Synthesis of PIPs at the plasma membrane";"T cell receptor signaling pathway"
XP_050485722.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050475057.1	6	Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253	"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock"
XP_050496798.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Human papillomavirus infection"
XP_050473994.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050494579.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050485392.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050477596.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000	"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Long-term potentiation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation"
XP_050475170.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050481161.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050481599.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_050485665.1	11	Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167243	"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery"
XP_050470559.1	20	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress"
XP_050469513.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050486767.1	6	Reactome: R-HSA-5620916;Reactome: R-HSA-6811438;Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"VxPx cargo-targeting to cilium";"Intra-Golgi traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050491383.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_050478510.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_050478030.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050482222.1	7	Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_050491840.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050486505.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050478855.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_050496425.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050480284.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050491537.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050482022.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050478067.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050482812.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050479228.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050497131.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050475650.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050470782.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050487557.1	4	KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-6823;MetaCyc: PWY-7887	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_050484199.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050490415.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050471071.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050489297.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_050490498.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050474724.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050475679.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050482377.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050476906.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050487741.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050493112.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050478380.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_050483126.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050472823.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_050491463.1	5	MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;Reactome: R-HSA-2426168	"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_050494330.1	3	Reactome: R-HSA-111465;Reactome: R-HSA-1660499;KEGG: 04660+2.7.10.2	"Apoptotic cleavage of cellular proteins";"Synthesis of PIPs at the plasma membrane";"T cell receptor signaling pathway"
XP_050492327.1	12	MetaCyc: PWY-3801;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238	"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Sucrose biosynthesis II"
XP_050491882.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050488578.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050482573.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050486309.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050470555.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_050476364.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events"
XP_050484769.1	6	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_050483277.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050480729.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050479552.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050494385.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050478278.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050482651.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_050488627.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050476483.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_050472003.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050493100.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050481304.1	42	Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-2299718;Reactome: R-HSA-4551638;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-977225;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-1221632;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-212300;Reactome: R-HSA-606279;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-3214847;Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-110329;Reactome: R-HSA-5334118;Reactome: R-HSA-5617472;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-110330	"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Condensation of Prophase Chromosomes";"SUMOylation of chromatin organization proteins";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Amyloid fiber formation";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"HDACs deacetylate histones";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Meiotic synapsis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"PRC2 methylates histones and DNA";"Deposition of new CENPA-containing nucleosomes at the centromere";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"RMTs methylate histone arginines";"HCMV Early Events";"HATs acetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged pyrimidine";"DNA methylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_050491858.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050470680.1	20	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress"
XP_050490974.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050480859.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050485011.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050491558.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050473778.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050483995.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_050476956.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050469879.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050478234.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050474902.1	9	KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-112043;MetaCyc: PWY-6351	"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_050484494.1	14	MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7783;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Anandamide biosynthesis I"
XP_050484255.1	7	Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684	"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state"
XP_050489255.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_050470445.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050493350.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050490004.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050479054.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050484883.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050496493.1	7	MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-7625;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11	"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI";"Phosphatidylinositol signaling system"
XP_050493785.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050485864.1	6	Reactome: R-HSA-2022854;Reactome: R-HSA-3000178;Reactome: R-HSA-3656243;Reactome: R-HSA-2022857;Reactome: R-HSA-3656225;Reactome: R-HSA-3656244	"Keratan sulfate biosynthesis";"ECM proteoglycans";"Defective ST3GAL3 causes MCT12 and EIEE15";"Keratan sulfate degradation";"Defective CHST6 causes MCDC1";"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"
XP_050477257.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050483035.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050471538.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_050488873.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050480277.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050482019.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_050478653.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_050487457.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050485730.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_050472474.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050489471.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050482387.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050491867.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050496406.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050478501.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050496581.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050479166.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050469881.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050485871.1	14	Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3"
XP_050488785.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050472752.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050471373.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050475121.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050485735.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050478517.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA"
XP_050479227.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050487308.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050493767.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050478652.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_050471038.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050487988.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050485829.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050491850.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050490711.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464	"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins"
XP_050482879.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050478968.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050490008.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050481536.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050479854.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050487570.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050491918.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050481336.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050476398.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050490264.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050481997.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050480384.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8964038	"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"Chylomicron clearance";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Scavenging by Class H Receptors";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"LDL remodeling";"VLDL assembly";"VLDL clearance";"Platelet sensitization by LDL";"LDL clearance"
XP_050470465.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993	"G alpha (z) signalling events";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors"
XP_050485995.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_050496126.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_050493772.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050493132.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050496820.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050480619.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050482292.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050494224.1	7	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis"
XP_050469922.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050484265.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050487151.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050493517.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050492655.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones"
XP_050470944.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050478237.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050469959.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050472665.1	17	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050482863.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050471377.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050488352.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050487110.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_050469921.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050477681.1	4	MetaCyc: PWY-7805;Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_050473820.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_050486222.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050472858.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050480320.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050473680.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050474656.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050477910.1	15	MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383	"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050483293.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050490997.1	15	Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5689896	"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases"
XP_050478547.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_050482550.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050490923.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_050487603.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050489478.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050489008.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050472996.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050491886.1	7	Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-606279;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"Ub-specific processing proteases";"UCH proteinases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Telomere Extension By Telomerase"
XP_050482469.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-3000170	"Molecules associated with elastic fibres";"ECM proteoglycans";"Integrin cell surface interactions";"Syndecan interactions"
XP_050490125.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050477368.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050473178.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050480976.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050474775.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050491963.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_050481932.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050473997.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_050473160.1	9	Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-6794361;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066	"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Long-term potentiation";"Neurexins and neuroligins";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_050471792.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050480054.1	30	Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-2564830;Reactome: R-HSA-6781823	"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Cytosolic iron-sulfur cluster assembly";"Formation of TC-NER Pre-Incision Complex"
XP_050495112.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV"
XP_050491875.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_050475215.1	9	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection"
XP_050475305.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_050488053.1	4	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism"
XP_050470080.1	14	Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_050485233.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050484870.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_050489854.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050494374.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_050490651.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050491728.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050475175.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050475214.1	9	KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection"
XP_050481871.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050491881.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050478714.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050477944.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_050494215.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_050491397.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050481400.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050479857.1	4	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation elongation"
XP_050474779.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050471811.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_050476829.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050473827.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_050496393.1	8	Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050478064.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050479981.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050483179.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050473998.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050475637.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050491540.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050476238.1	8	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo"
XP_050474680.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins"
XP_050475749.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-983168;Reactome: R-HSA-3065676	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)"
XP_050474429.1	9	Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-975634	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Retinoid metabolism and transport"
XP_050482244.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050477151.1	17	KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6608;MetaCyc: PWY-6609;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-5532;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611	"Pyrimidine metabolism";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage III";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V"
XP_050489674.1	4	Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-912631	"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction";"Regulation of signaling by CBL"
XP_050475639.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050477780.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_050488320.1	9	Reactome: R-HSA-3371599;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-196780;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142	"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050489467.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050486270.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050472879.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_050494250.1	11	Reactome: R-HSA-114604;Reactome: R-HSA-909733;Reactome: R-HSA-877312;Reactome: R-HSA-9008059;Reactome: R-HSA-912694;Reactome: R-HSA-210990;Reactome: R-HSA-391160;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-512988;Reactome: R-HSA-388841	"GPVI-mediated activation cascade";"Interferon alpha/beta signaling";"Regulation of IFNG signaling";"Interleukin-37 signaling";"Regulation of IFNA signaling";"PECAM1 interactions";"Signal regulatory protein family interactions";"Platelet sensitization by LDL";"PD-1 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family"
XP_050476164.1	13	MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7254	"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)"
XP_050487833.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_050483518.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050496520.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050496411.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-193681;Reactome: R-HSA-5626978	"Glycosphingolipid metabolism";"Ceramide signalling";"TNFR1-mediated ceramide production"
XP_050475471.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_050469396.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050482117.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050472454.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050488518.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050493494.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_050489616.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050482053.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050478932.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050492369.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050488327.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050490286.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050473728.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050469559.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050471618.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050485446.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050476429.1	5	MetaCyc: PWY-7204;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;Reactome: R-HSA-964975	"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate"
XP_050480234.1	10	MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_050469960.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050481552.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_050476108.1	16	MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-2046105;MetaCyc: PWY-6433;Reactome: R-HSA-2046106;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Linoleic acid (LA) metabolism";"Hydroxylated fatty acid biosynthesis (plants)";"alpha-linolenic acid (ALA) metabolism";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)"
XP_050492593.1	4	KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_050483847.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050471667.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050494110.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050476178.1	7	MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-6922	"Urea cycle";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Canavanine degradation";"Arginine biosynthesis";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis"
XP_050482789.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050482167.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050472723.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050486593.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050487475.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-5173105	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation"
XP_050487992.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050483317.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-445355	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Platelet degranulation";"Smooth Muscle Contraction"
XP_050478105.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_050486006.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_050489320.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050484890.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050489104.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050486830.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050489986.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation"
XP_050477545.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050494137.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_050493211.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-1632852;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Macroautophagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Intraflagellar transport";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050495531.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_050483359.1	5	Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558	"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_050486752.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050493757.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050473256.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050495907.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050470095.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_050479021.1	7	Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684	"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state"
XP_050486939.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050489388.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050486077.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050496158.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050491073.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050476236.1	16	Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-1250342;Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-1250347	"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB4 signaling";"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling"
XP_050484250.1	7	Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684	"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state"
XP_050485791.1	10	KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70263;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;MetaCyc: PWY-6142	"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Gluconeogenesis";"Inositol phosphate metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050477651.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_050478982.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050494192.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050482513.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050479936.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050494540.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050472565.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_050488217.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_050496389.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050477419.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050494273.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_050481228.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050478530.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949	"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin"
XP_050476508.1	19	KEGG: 00240+2.7.4.6;Reactome: R-HSA-380270;Reactome: R-HSA-380320;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7176	"Pyrimidine metabolism";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis"
XP_050492007.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-432720	"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis"
XP_050484041.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050487961.1	13	KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7821;MetaCyc: PWY-7187	"Riboflavin metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_050483278.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050478498.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050470965.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050471617.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_050486534.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050493705.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050496839.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050494020.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050482669.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"Protein ubiquitination";"Regulation of PTEN stability and activity";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
XP_050485874.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050492831.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050492991.1	12	Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction";"Purine metabolism"
XP_050485120.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_050486680.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050487234.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050480634.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050481931.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050489461.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050481879.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050486611.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_050482418.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050486635.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_050471238.1	18	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050484679.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_050493089.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050472494.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050485524.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050496161.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050484710.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050481559.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050474773.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050496488.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050487869.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050471983.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_050492143.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050490663.1	18	MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4	"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism"
XP_050491553.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050490468.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection"
XP_050481480.1	16	Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-512988;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-194840;Reactome: R-HSA-2219530	"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"G alpha (q) signalling events";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of signaling by CBL";"RET signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_050470318.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050471052.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_050493377.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050489058.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050480784.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050486427.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation"
XP_050478620.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050484195.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050484536.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050483007.1	5	KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-7761	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)"
XP_050482456.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050484835.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050487377.1	19	Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5687128;Reactome: R-HSA-5626467;Reactome: R-HSA-389359;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-194840	"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"Myogenesis";"EGFR downregulation";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"MAPK6/MAPK4 signaling";"RHO GTPases activate IQGAPs";"CD28 dependent Vav1 pathway";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle"
XP_050492121.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_050482673.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_050478750.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050496960.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050486225.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050486236.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_050492846.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050483653.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050473068.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050478473.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050482175.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050469944.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050472450.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050489621.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050491966.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050485505.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050487115.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050477403.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050475033.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050477563.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050477444.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_050480247.1	10	MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6361	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_050476783.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050473793.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_050480471.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050482155.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050470702.1	10	KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04150+2.7.1.153	"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"mTOR signaling pathway"
XP_050477611.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952	"Trafficking of AMPA receptors";"Long-term potentiation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions"
XP_050485484.1	8	Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9620244	"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation"
XP_050472500.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050482391.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050490068.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050496427.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050482399.1	4	KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685;Reactome: R-HSA-2393930;KEGG: 00240+3.6.1.17	"Purine metabolism";"Detoxification of Reactive Oxygen Species";"Phosphate bond hydrolysis by NUDT proteins";"Pyrimidine metabolism"
XP_050487697.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050473064.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050496539.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050475301.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616	"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication"
XP_050470978.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050474108.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050494587.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050469673.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050484160.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050488794.1	6	Reactome: R-HSA-2892245;Reactome: R-HSA-8986944;Reactome: R-HSA-3769402;Reactome: R-HSA-6785807;Reactome: R-HSA-452723;Reactome: R-HSA-2892247	"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Transcriptional Regulation by MECP2";"Deactivation of the beta-catenin transactivating complex";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation of pluripotent stem cells";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"
XP_050475209.1	9	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection"
XP_050474103.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122	"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
XP_050482631.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050487633.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050478388.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050477641.1	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050471363.1	4	Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_050484221.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050477900.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_050492476.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050476078.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050472575.1	7	KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121	"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_050491446.1	2	Reactome: R-HSA-69231;Reactome: R-HSA-8934593	"Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity"
XP_050472994.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050475100.1	11	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050490416.1	3	Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_050491128.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050485767.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_050496822.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050493056.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050471247.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis"
XP_050469766.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050479339.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-8866907;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-3371568	"Circadian Clock";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Activation of the TFAP2 (AP-2) family of transcription factors";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Attenuation phase"
XP_050469882.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050472092.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_050477054.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201	"PPARA activates gene expression";"snRNP Assembly";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050495904.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050478077.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050489555.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050474803.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050473963.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050482819.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050477667.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation"
XP_050472496.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050481510.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050475345.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-6784531	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus"
XP_050472236.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050478651.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_050480251.1	10	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_050487646.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050480132.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050495102.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050493653.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050476992.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050481188.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
XP_050488520.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050475963.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050492018.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050492370.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050471188.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050480958.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050482299.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050477933.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape"
XP_050475872.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_050474834.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050493106.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050471677.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050485592.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_050483100.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050481822.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050485989.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol"
XP_050482016.1	6	MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664	"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_050478988.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050486974.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050476020.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050489165.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050496492.1	7	MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226	"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"Synthesis of PI"
XP_050478493.1	57	Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-68827	"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex"
XP_050485724.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050470597.1	57	Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276	"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_050475986.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050480633.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050471863.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_050485823.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_050479123.1	4	Reactome: R-HSA-8866427;Reactome: R-HSA-9031525;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050478718.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050478384.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050493650.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050471960.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050479374.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050480816.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050485578.1	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
XP_050489273.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050489336.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050481409.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050472451.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050492495.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050481466.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050483352.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050480239.1	10	KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050471084.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050478749.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050474748.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050482520.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050482240.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050471375.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050485631.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_050484684.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920	"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)"
XP_050483821.1	11	KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-2029485;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4	"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_050470417.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050496611.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050477159.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_050496065.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_050491004.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050491494.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes"
XP_050492112.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_050492918.1	4	Reactome: R-HSA-879415;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_050476056.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050493692.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050496612.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050492572.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_050485268.1	26	Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Kinesins";"Recycling pathway of L1";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050473852.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857	"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Keratan sulfate degradation"
XP_050489809.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_050481015.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_050493220.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050473737.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050470890.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050489515.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_050481204.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050488350.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050471766.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050489628.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050476430.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050487084.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_050477028.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050487866.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050477824.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050472576.1	7	MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_050472729.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_050492003.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_050471708.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050485021.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050471378.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050471773.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050479211.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_050480489.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050471995.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050478565.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050481236.1	10	KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis"
XP_050493947.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050471846.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050482104.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050470244.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050496547.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-179409	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A"
XP_050488241.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_050487981.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434	"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050471905.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050474712.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050469599.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050486753.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050488691.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050486560.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050487408.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050490241.1	24	Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-416476	"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events"
XP_050484141.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050475577.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050493382.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050493385.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050488340.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050477460.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050486571.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050469923.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050489643.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050469819.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050493508.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050476821.1	6	MetaCyc: PWY-7900;Reactome: R-HSA-3322077;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)"
XP_050476611.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050483094.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050483764.1	10	MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;Reactome: R-HSA-6798695;Reactome: R-HSA-975634;Reactome: R-HSA-3000171;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-2453864;Reactome: R-HSA-977225	"Urate conversion to allantoin III";"Purine metabolism";"Neutrophil degranulation";"Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Retinoid cycle disease events";"Amyloid fiber formation"
XP_050487038.1	12	KEGG: 00130+1.14.99.60;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-7230	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_050482524.1	19	Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-182971;Reactome: R-HSA-525793;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-8950505;Reactome: R-HSA-389359;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5687128	"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"EGFR downregulation";"Myogenesis";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"CD28 dependent Vav1 pathway";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"MAPK6/MAPK4 signaling"
XP_050476187.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_050475557.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050488624.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295	"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation"
XP_050472837.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050489769.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_050487332.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050470347.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050481903.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050484272.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050485987.1	6	Reactome: R-HSA-1855204;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050486060.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050482226.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050477995.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050479132.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050475089.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050480224.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050488181.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050493755.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050496367.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201	"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050493370.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis"
XP_050476170.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8055	"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_050476002.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050481889.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050488728.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050493799.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050486920.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050478979.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050473098.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050485473.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050491479.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9609690	"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events"
XP_050472738.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050479299.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332	"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Recycling pathway of L1";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin"
XP_050480306.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050491919.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050481497.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050485478.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050485756.1	7	Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7818;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886	"Synthesis of PE";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Synthesis of PC";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_050471054.1	6	MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861	"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050478797.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050487740.1	37	Reactome: R-HSA-168271;Reactome: R-HSA-983170;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-204005;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5663220	"Transport of Ribonucleoproteins into the Host Nucleus";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"COPII-mediated vesicle transport";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins"
XP_050470451.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-167200;Reactome: R-HSA-975956;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-9010553;Reactome: R-HSA-159227;Reactome: R-HSA-73856;Reactome: R-HSA-112382;Reactome: R-HSA-72187;Reactome: R-HSA-167242;Reactome: R-HSA-77588;Reactome: R-HSA-8851708;Reactome: R-HSA-111367;Reactome: R-HSA-975957;Reactome: R-HSA-159230;Reactome: R-HSA-6803529	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Regulation of expression of SLITs and ROBOs";"Transport of the SLBP independent Mature mRNA";"RNA Polymerase II Transcription Termination";"Formation of RNA Pol II elongation complex";"mRNA 3'-end processing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Signaling by FGFR2 IIIa TM";"SLBP independent Processing of Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP Dependant Mature mRNA";"FGFR2 alternative splicing"
XP_050492878.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_050470557.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_050487052.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050475251.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex"
XP_050487709.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_050489963.1	10	Reactome: R-HSA-8856825;Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity"
XP_050478394.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050489997.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_050470858.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050483909.1	22	MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-6433;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-8041;MetaCyc: PWY-7726;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602	"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050487817.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050489319.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050489185.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_050490901.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_050487138.1	11	KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-5381;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-5695;MetaCyc: PWY-7185;MetaCyc: PWY-6608;MetaCyc: PWY-6596;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606	"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Purine metabolism";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation II"
XP_050476812.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_050482474.1	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050471016.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_050476886.1	29	Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-69541;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6796648;Reactome: R-HSA-349425;Reactome: R-HSA-912446;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-6803207;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-6804760;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6803204	"Regulation of TP53 Degradation";"Thermogenesis";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Stabilization of p53";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"TP53 Regulates Transcription of Caspase Activators and Caspases";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Methylation";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_050481598.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_050482227.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050490496.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050479834.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050473562.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050483531.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050485581.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90	"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_050488936.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050469527.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050480319.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050487832.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_050488525.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050486603.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050472992.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050469537.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050486441.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050471376.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050469422.1	18	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-166208;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"mTORC1-mediated signalling";"Viral mRNA Translation";"Translation initiation complex formation"
XP_050492459.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050482552.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050494331.1	3	Reactome: R-HSA-111465;Reactome: R-HSA-1660499;KEGG: 04660+2.7.10.2	"Apoptotic cleavage of cellular proteins";"Synthesis of PIPs at the plasma membrane";"T cell receptor signaling pathway"
XP_050475172.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050472732.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050489140.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325	"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis"
XP_050494090.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050494776.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050478013.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-164944;Reactome: R-HSA-8849471;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"Nef and signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of actin dynamics for phagocytic cup formation"
XP_050493234.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050473393.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050484887.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050491599.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_050489512.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050489080.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050496402.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050471791.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050475994.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050471360.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_050478499.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050488652.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050491851.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050492751.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_050481678.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050492451.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050480513.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis"
XP_050474512.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389	"Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases"
XP_050474283.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis"
XP_050472889.1	6	KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;MetaCyc: PWY-6906;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_050485306.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050493795.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050491507.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050489510.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050475844.1	5	MetaCyc: PWY-8060;Reactome: R-HSA-6798695;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180	"2-deoxy-D-ribose degradation I";"Neutrophil degranulation";"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation"
XP_050478503.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050490731.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050480487.1	5	Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9630221	"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing"
XP_050485620.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_050481672.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050481976.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"Neutrophil degranulation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050471241.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050485131.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_050479053.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050478375.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050492915.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050479710.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_050481616.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_050469942.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050473489.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050475687.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050471852.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_050490206.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050483406.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050479859.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050482247.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_050473792.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_050486625.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050480122.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050481609.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_050471728.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050474417.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050485062.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_050481690.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050483268.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050474726.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050483250.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050496361.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400206	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Circadian Clock";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha"
XP_050481222.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050496916.1	3	Reactome: R-HSA-420029;Reactome: R-HSA-4608870;Reactome: R-HSA-2173791	"Tight junction interactions";"Asymmetric localization of PCP proteins";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_050482173.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050487190.1	34	Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333	"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050470448.1	29	Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex"
XP_050493699.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050496462.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_050486847.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050486426.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050491385.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_050496159.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050492252.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050478239.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050483222.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050487152.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050482807.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050486059.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050481438.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050483026.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_050491632.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050485664.1	11	Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation"
XP_050470688.1	33	Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885	"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins"
XP_050493734.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050478856.1	11	Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"mTOR signaling pathway";"Thermogenesis";"IRF3-mediated induction of type I IFN";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_050477635.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_050469427.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050485403.1	17	KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;MetaCyc: PWY-5789;Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2	"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism"
XP_050479117.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050486250.1	11	Reactome: R-HSA-163680;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1	"AMPK inhibits chREBP transcriptional activation activity";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection"
XP_050481589.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270	"Ub-specific processing proteases";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050483907.1	22	MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;Reactome: R-HSA-75876;MetaCyc: PWY-6958	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)"
XP_050486551.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050489387.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_050481330.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_050476951.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_050493524.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050489377.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_050482224.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050496522.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050477564.1	5	KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16	"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050481795.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050491746.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_050493116.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050472203.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050488028.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050485723.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050481712.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050474743.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050472751.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050473241.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050479807.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-114508	"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Ca2+ pathway";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis"
XP_050476157.1	5	KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_050470249.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050471655.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050471173.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050470412.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050488869.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050477883.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214	"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins"
XP_050478596.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050492927.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050489456.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050477861.1	13	Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5537	"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V"
XP_050485401.1	17	MetaCyc: PWY-5966-1;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-200425	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Carnitine metabolism"
XP_050492183.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_050472140.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_050493943.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_050487778.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050477541.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_050473240.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050485695.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation"
XP_050472964.1	7	Reactome: R-HSA-196780;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13	"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_050488537.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050486892.1	8	Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange"
XP_050494414.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050491234.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461	"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation"
XP_050494237.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_050489003.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_050490982.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050493074.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050486586.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050472499.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050484899.1	5	KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_050490285.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050487600.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050481857.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050484249.1	7	Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838	"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO"
XP_050491975.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050490587.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050488549.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_050472731.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_050471401.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050492141.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050482599.1	5	Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050475676.1	32	Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167238	"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050484312.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050478941.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_050483077.1	8	Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1	"Glycolysis";"Galactose metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism"
XP_050475663.1	11	Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-3861;MetaCyc: PWY-5659;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456	"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation"
XP_050484837.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050487752.1	52	Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163	"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway"
XP_050470701.1	10	Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04150+2.7.1.153	"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection";"Phosphatidylinositol signaling system";"Human papillomavirus infection";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"mTOR signaling pathway"
XP_050476079.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050481968.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_050476711.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050482015.1	6	Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_050478923.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050485005.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050483226.1	3	KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_050490598.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism"
XP_050474018.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050490695.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050491860.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050491502.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"Interleukin-7 signaling"
XP_050491006.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050477033.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050472592.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_050481224.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050486540.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050474528.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050490024.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050474633.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_050489307.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050484254.1	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798	"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell"
XP_050491605.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050478076.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050471159.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-882;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8	"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism"
XP_050486796.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_050488933.1	52	Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-76061;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-6781827;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-76071	"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050479965.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050469556.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050493809.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050471402.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050483288.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050493012.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050477661.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050475145.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050470378.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050475117.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050483251.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050479375.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050472211.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787	"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Hedgehog 'off' state"
XP_050470734.1	3	KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_050483629.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050480501.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050477297.1	57	Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837	"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation"
XP_050490530.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-190840	"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Recycling pathway of L1";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_050473046.1	20	Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI"
XP_050475766.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050479871.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050492078.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_050472227.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050478397.1	8	Reactome: R-HSA-6787639;MetaCyc: PWY-5738;MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-66;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740	"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis"
XP_050474102.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-913709;MetaCyc: PWY-7433	"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation"
XP_050472239.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050480051.1	30	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-2564830;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-73863	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cytosolic iron-sulfur cluster assembly";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Dual Incision in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination"
XP_050479755.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050480499.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050488666.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050489164.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050483013.1	5	MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050482753.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050484147.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050484321.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_050483626.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050483645.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050487625.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050480349.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050473307.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050489824.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050489020.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050469698.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050486916.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050474753.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050491070.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050485333.1	14	MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_050488152.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050481900.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_050491955.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050475825.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_050475830.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-70370;Reactome: R-HSA-5609977	"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_050481210.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050486917.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050470115.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050478106.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050473937.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050480956.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050487231.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6781823	"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex"
XP_050480120.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050474386.1	15	Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_050471857.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050489292.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050479387.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050491394.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050490371.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_050491604.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050496703.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665	"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_050487479.1	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050483064.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050492276.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_050493523.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050477698.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050478280.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050471078.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_050483857.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050491212.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-389513	"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling"
XP_050485324.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_050493125.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050472156.1	16	Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-975110;Reactome: R-HSA-975871;Reactome: R-HSA-975155;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5603037;Reactome: R-HSA-5602498;Reactome: R-HSA-1810476;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-166058;Reactome: R-HSA-1236974;Reactome: R-HSA-5603041;Reactome: R-HSA-9020702	"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"ER-Phagosome pathway";"IRAK4 deficiency (TLR2/4)";"Interleukin-1 signaling"
XP_050472071.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050493618.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_050493011.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050487329.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050471526.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_050490040.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050475034.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050474077.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050481529.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-6782315	"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Methylation";"tRNA modification in the nucleus and cytosol"
XP_050489895.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050489904.1	4	KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603	"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine"
XP_050487280.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050475467.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050479720.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050470889.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050476581.1	10	KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7385	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Galactose metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)"
XP_050480046.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050474965.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050471679.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050475304.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050471395.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_050485448.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050493847.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050483630.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050487462.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050470678.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050485577.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90	"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_050473904.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050487407.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050473221.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050485171.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_050484830.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050490583.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050469523.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050490576.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050485471.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050481704.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050484833.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050482098.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_050472452.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050483324.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants"
XP_050481403.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism"
XP_050480812.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050472779.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050484760.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-983168	"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050485728.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050493696.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050494769.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050479753.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050476008.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050485167.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050493197.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050493670.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050485260.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050483856.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050486909.1	4	MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_050475853.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_050472379.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050488782.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050473686.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050470694.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180746	"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Nuclear import of Rev protein"
XP_050486357.1	9	Reactome: R-HSA-8963684;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5	"Tyrosine catabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism"
XP_050473570.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050473896.1	5	Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-162710;Reactome: R-HSA-162699	"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of glycosylphosphatidylinositol (GPI)";"Synthesis of dolichyl-phosphate mannose"
XP_050486271.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_050469758.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702	"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling"
XP_050494071.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050491642.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_050478617.1	8	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Signaling by Hippo";"PI3K-Akt signaling pathway"
XP_050486397.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_050469986.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050470878.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050489762.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-983168	"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Josephin domain DUBs";"Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050483988.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases"
XP_050483457.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-5826	"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis"
XP_050477168.1	22	MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7726;MetaCyc: PWY-7601;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-6958	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)"
XP_050482096.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_050488379.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050484897.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050480790.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050477776.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_050492128.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_050490025.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050490692.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282	"Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_050469575.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168276	"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways"
XP_050477096.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_050476298.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050493336.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050493349.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_050481499.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050486329.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050483509.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050485450.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050480840.1	7	Reactome: R-HSA-2122947;Reactome: R-HSA-212436;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2173796	"NOTCH1 Intracellular Domain Regulates Transcription";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_050484585.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050485173.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_050490584.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050478500.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050476941.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_050474388.1	14	MetaCyc: PWY-5695;MetaCyc: PWY-6607;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5497;MetaCyc: PWY-6538;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6606;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6999;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6596;MetaCyc: PWY-6608;Reactome: R-HSA-74259;Reactome: R-HSA-8851680	"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Purine metabolism";"Guanosine nucleotides degradation II";"Caffeine metabolism";"Theophylline degradation";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine catabolism";"Butyrophilin (BTN) family interactions"
XP_050485336.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_050485414.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050491384.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin"
XP_050471021.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_050480800.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_050494640.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_050485318.1	6	MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050486027.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050483275.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_050471517.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_050492330.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050473438.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050492792.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway"
XP_050472226.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050495830.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_050472640.1	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050480732.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050480079.1	3	KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050482017.1	6	MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442	"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_050479133.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050476744.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050486942.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050472571.1	7	KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-7282;MetaCyc: PWY-6122;MetaCyc: PWY-6121	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_050485625.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)"
XP_050470120.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050486008.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459	"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050473578.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050486244.1	25	Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-380270;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"HCMV Early Events";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins"
XP_050472129.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050483731.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050489926.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050479072.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050475678.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050479370.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050475115.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050490722.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050470967.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050472801.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050471311.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_050485163.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050484561.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050495891.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050478447.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape"
XP_050470342.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050473015.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050484654.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050470221.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_050477489.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050484397.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050481451.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_050472626.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050489258.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_050477415.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050487116.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_050490302.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_050470622.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050496803.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050481803.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_050480476.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050493520.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050476296.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050472741.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_050481961.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236	"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_050493707.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050490492.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050470708.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_050475785.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_050482764.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050469888.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050479225.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050470924.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050472788.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050487711.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_050487691.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381426	"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050475485.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_050491215.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-432142	"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL"
XP_050491412.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_050496757.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050473999.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050479858.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050469937.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050478229.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050493018.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050472985.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050483564.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050493030.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050481987.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_050484151.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050485101.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050485697.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins"
XP_050471769.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_050494222.1	7	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_050471874.1	8	MetaCyc: PWY-4984;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;Reactome: R-HSA-70635;KEGG: 00220+6.3.4.5;MetaCyc: PWY-5;MetaCyc: PWY-5154;MetaCyc: PWY-4983	"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Arginine biosynthesis";"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)"
XP_050479754.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050485741.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050488326.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050481535.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050480992.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657	"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes"
XP_050487693.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050469371.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050487087.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_050494375.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050489075.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_050469618.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050490072.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050482370.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050470764.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050488124.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050483330.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948	"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants"
XP_050480308.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050489906.1	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism"
XP_050484523.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050481701.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050487217.1	11	Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700	"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_050469889.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379	"Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres"
XP_050490284.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050493539.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416	"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_050496369.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1989781	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"PPARA activates gene expression"
XP_050496800.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050492842.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050476214.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050495205.1	5	MetaCyc: PWY-6692;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7082	"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_050486931.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050493845.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_050495042.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_050485528.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050491541.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050477470.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050483964.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050482681.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_050484692.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_050489286.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050491623.1	5	Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638	"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway"
XP_050489326.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_050482563.1	11	Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-428890	"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling"
XP_050488161.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050471544.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050470380.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050496969.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050469891.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases"
XP_050490267.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050472799.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050482371.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-418594	"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G alpha (i) signalling events"
XP_050471121.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_050482767.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_050477811.1	3	MetaCyc: PWY-5996;MetaCyc: PWY-5987;Reactome: R-HSA-75105	"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis"
XP_050486895.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050486709.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050477119.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050479837.1	4	KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004	"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I"
XP_050481320.1	14	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-69273;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_050493417.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050496405.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050489485.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050489682.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050493029.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050494197.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050490472.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050486781.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050474774.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050488096.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_050491968.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050486924.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943	"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_050482314.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050480652.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050496844.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050496652.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050493511.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_050470094.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_050481654.1	42	Reactome: R-HSA-110329;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-5250924;Reactome: R-HSA-110330;Reactome: R-HSA-5334118;Reactome: R-HSA-5617472;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-212300;Reactome: R-HSA-606279;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-1221632;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-977225;Reactome: R-HSA-5625886;Reactome: R-HSA-2299718;Reactome: R-HSA-4551638;Reactome: R-HSA-912446;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-2559580;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-8939236;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-2559586	"Cleavage of the damaged pyrimidine";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA methylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"PRC2 methylates histones and DNA";"Deposition of new CENPA-containing nucleosomes at the centromere";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"Meiotic synapsis";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Condensation of Prophase Chromosomes";"SUMOylation of chromatin organization proteins";"Meiotic recombination";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"Oxidative Stress Induced Senescence";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence"
XP_050472136.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_050472134.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050478841.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_050490506.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050470277.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050481187.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050469880.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050483576.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050476808.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050469971.1	11	KEGG: 00720+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-6549;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42	"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)"
XP_050485700.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877	"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase"
XP_050476171.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5981;Reactome: R-HSA-1483166	"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA"
XP_050469949.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_050482808.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050485771.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_050478112.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_050496853.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_050487328.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050476904.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050482406.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050483719.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050477423.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050491974.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050487279.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050470725.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050470382.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050479699.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050477081.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050470568.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-6784531	"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus"
XP_050493427.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050483993.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050478138.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050485739.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050473985.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050486338.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050474831.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050485332.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)"
XP_050489739.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050495040.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050487085.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_050478723.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050485608.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_050472886.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050492526.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050470674.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050478755.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050482389.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493607.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050480514.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050492358.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050487610.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050492347.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050481223.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050489269.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050488216.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050476509.1	19	MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-6545;Reactome: R-HSA-380270;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;Reactome: R-HSA-380320;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"CMP phosphorylation"
XP_050483384.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-5136	"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_050476999.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050469750.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424	"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Neddylation";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling"
XP_050473564.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050475375.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050482248.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050470230.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_050482660.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050489299.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050481680.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050472908.1	8	KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5269;Reactome: R-HSA-1483148	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis II";"Synthesis of PG"
XP_050493240.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050493351.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050472165.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050493222.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_050486546.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_050480321.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050479179.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050473385.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050484377.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050484517.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050496622.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050477085.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924	"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Intraflagellar transport"
XP_050481427.1	15	Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
XP_050487484.1	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050482157.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050488212.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_050487850.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050484149.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050488823.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050470818.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897	"Macroautophagy";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes"
XP_050472124.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_050490844.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050481481.1	16	Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-912526;Reactome: R-HSA-388841	"G alpha (q) signalling events";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family"
XP_050487320.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050480052.1	30	Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-2564830;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-6781827	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cytosolic iron-sulfur cluster assembly";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_050474080.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050488553.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_050491848.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050477221.1	9	Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12	"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis / Gluconeogenesis"
XP_050487202.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_050476796.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_050491979.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_050491628.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050470388.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_050489270.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050482966.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050485726.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050490995.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-195253	"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex"
XP_050480331.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_050485061.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_050486616.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050474492.1	3	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import"
XP_050469710.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050480857.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-168928;Reactome: R-HSA-9639288	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Amino acids regulate mTORC1"
XP_050493014.1	15	Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated"
XP_050479161.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050475739.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050492110.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050476040.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050469467.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050473483.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050482824.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050480045.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050483312.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-114608	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Platelet degranulation"
XP_050487841.1	11	Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation"
XP_050482523.1	19	Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5687128;Reactome: R-HSA-5663220;Reactome: R-HSA-389359;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-525793;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-182971	"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"MAPK6/MAPK4 signaling";"RHO GTPases Activate Formins";"CD28 dependent Vav1 pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"Myogenesis";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"EGFR downregulation"
XP_050480105.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050493396.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050476838.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050484123.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050478811.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050477600.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244	"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation"
XP_050478497.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050473354.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050483655.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050482522.1	19	Reactome: R-HSA-194840;Reactome: R-HSA-8950505;Reactome: R-HSA-389359;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-8964616;Reactome: R-HSA-525793;Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-3928662;Reactome: R-HSA-418885;Reactome: R-HSA-4420097	"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"CD28 dependent Vav1 pathway";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"EGFR downregulation";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"G beta:gamma signalling through CDC42";"Myogenesis";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"EPHB-mediated forward signaling";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway"
XP_050472963.1	12	MetaCyc: PWY-6277;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6122;MetaCyc: PWY-6613;KEGG: 00230+6.3.4.13;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00670+2.1.2.2;Reactome: R-HSA-196780;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Biotin transport and metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_050469939.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_050473857.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Photosynthesis";"ATP biosynthesis";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050490640.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050494227.1	7	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050477314.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050482484.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050474420.1	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2	"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050478469.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050493771.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050480053.1	30	Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-2564830;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-75953	"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Cytosolic iron-sulfur cluster assembly";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation"
XP_050482915.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050471697.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13	"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism"
XP_050475053.1	4	KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis"
XP_050470603.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050486282.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050493701.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_050476161.1	5	KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_050480524.1	3	Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320	"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH"
XP_050471358.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050470505.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050491879.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050484322.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_050489324.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050487485.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-71240	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane";"Tryptophan catabolism"
XP_050472517.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050483971.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050492134.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050471286.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_050472644.1	5	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050483693.1	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_050477657.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050490248.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050471230.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes"
XP_050478975.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation"
XP_050484407.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_050481912.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_050475477.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050475262.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050488538.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050494935.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050489057.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050485682.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444	"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050478594.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050481807.1	6	Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12	"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_050487918.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_050475189.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050490127.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050492491.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050489036.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050470579.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050488510.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-68949	"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin"
XP_050483937.1	5	Reactome: R-HSA-532668;MetaCyc: PWY-7919;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)"
XP_050482337.1	7	MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-5695;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695	"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Neutrophil degranulation"
XP_050485474.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050490987.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_050471896.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050469913.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050476480.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050490413.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-4381	"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_050484685.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)"
XP_050487473.1	8	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation"
XP_050490066.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050490669.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_050482832.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_050496855.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050487236.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050492691.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166	"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2"
XP_050492356.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050488632.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050482751.1	11	MetaCyc: PWY-6898;Reactome: R-HSA-532668;MetaCyc: PWY-6907;Reactome: R-HSA-879415;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-196819;Reactome: R-HSA-8957275;MetaCyc: PWY-7356	"Thiamine salvage III";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Advanced glycosylation endproduct receptor signaling";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Vitamin B1 (thiamin) metabolism";"Post-translational protein phosphorylation";"Thiamine salvage IV (yeast)"
XP_050477474.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050485462.1	12	Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-977225	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation"
XP_050491957.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128	"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling"
XP_050471928.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_050472745.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1"
XP_050482737.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050487371.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050491888.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050475395.1	9	Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664	"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Neddylation"
XP_050476080.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050496888.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_050494771.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_050477135.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050492118.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_050487235.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050492654.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_050491047.1	7	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism"
XP_050482831.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_050490811.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050472812.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_050470029.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050469892.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_050488571.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
XP_050483074.1	8	KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1	"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Streptomycin biosynthesis"
XP_050477875.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"MET activates PTK2 signaling"
XP_050471915.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050490281.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050493013.1	15	Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-111465	"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins"
XP_050480650.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050496414.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-193681;Reactome: R-HSA-5626978	"Glycosphingolipid metabolism";"Ceramide signalling";"TNFR1-mediated ceramide production"
XP_050490021.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050484764.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050486360.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_050493776.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_050470174.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_050487643.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050484904.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-6804114	"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_050487629.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050483069.1	8	KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050473014.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050490449.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050474053.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050496756.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050476023.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050471509.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_050472316.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050479046.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050471988.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399	"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_050489359.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050474342.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-72203;Reactome: R-HSA-9610379	"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events"
XP_050469846.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050483581.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050469749.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050488664.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050476373.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_050473626.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_050491468.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050475284.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050469671.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050475966.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050483347.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050483900.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050479803.1	13	Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-5578775	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis"
XP_050477405.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050473375.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050472225.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050483376.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050484269.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050472797.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050470576.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050479405.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_050472836.1	14	KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-3781;MetaCyc: PWY-6969;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403	"Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)"
XP_050477313.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050484220.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_050474527.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050475583.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_050472629.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050485996.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_050488871.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050483753.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050478598.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050487979.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050472090.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_050495053.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_050482085.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050483515.1	6	MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycolysis / Gluconeogenesis"
XP_050475211.1	9	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050491647.1	7	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14	"Thiamine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_050495501.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_050473418.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050494234.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_050485231.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050487436.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_050492841.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050480686.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050491691.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050483499.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050489111.1	6	KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15	"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism"
XP_050473553.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050472815.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_050485456.1	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_050496340.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_050480350.1	24	Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-202424;Reactome: R-HSA-2730905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-2871837;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5625740;Reactome: R-HSA-392451	"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"Downstream TCR signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Thermogenesis";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"Human cytomegalovirus infection";"RSK activation";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"FCERI mediated NF-kB activation";"Human papillomavirus infection";"Activation of AKT2";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma"
XP_050494130.1	4	KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_050496867.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050491555.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_050485538.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050482066.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050490407.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050479236.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050476362.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_050489777.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050496429.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050487977.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050496956.1	5	Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720	"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis"
XP_050482515.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050474744.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050473352.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050477908.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383	"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Glycerol degradation to butanol";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050489302.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050478021.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050486203.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050470282.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050486594.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050486945.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050473587.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050486443.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050493617.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination"
XP_050485801.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050478111.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_050482459.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050485413.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050480789.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway"
XP_050482852.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050479456.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471	"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_050492768.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050486464.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050481496.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050473906.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050472430.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_050486413.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050491491.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-8939243	"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050483316.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948	"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Platelet degranulation";"Smooth Muscle Contraction";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants"
XP_050487246.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_050490912.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050470667.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050493779.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_050479272.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050494004.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050479467.1	4	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis"
XP_050486100.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_050477252.1	16	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-2559586	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence"
XP_050472158.1	44	Reactome: R-HSA-881907;Reactome: R-HSA-3371453;Reactome: R-HSA-9635465;Reactome: R-HSA-9634638;Reactome: R-HSA-170968;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-456926;Reactome: R-HSA-8943724;Reactome: R-HSA-5654733;Reactome: R-HSA-202670;KEGG: 04150+2.7.11.24;Reactome: R-HSA-74749;Reactome: R-HSA-2559580;Reactome: R-HSA-375165;Reactome: R-HSA-2871796;Reactome: R-HSA-879415;Reactome: R-HSA-6811558;Reactome: R-HSA-112409;Reactome: R-HSA-8939211;Reactome: R-HSA-2559582;Reactome: R-HSA-5674499;Reactome: R-HSA-8940973;Reactome: R-HSA-6802955;Reactome: R-HSA-5654726;Reactome: R-HSA-162658;Reactome: R-HSA-982772;Reactome: R-HSA-444257;Reactome: R-HSA-198753;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-5654727;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-1295596;Reactome: R-HSA-5668599;Reactome: R-HSA-5673001;Reactome: R-HSA-450341;Reactome: R-HSA-9627069;Reactome: R-HSA-445144;Reactome: R-HSA-5674135;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-6802952	"Gastrin-CREB signalling pathway via PKC and MAPK";"Regulation of HSF1-mediated heat shock response";"Suppression of apoptosis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Frs2-mediated activation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Thrombin signalling through proteinase activated receptors (PARs)";"Regulation of PTEN gene transcription";"Negative regulation of FGFR4 signaling";"ERKs are inactivated";"mTOR signaling pathway";"Signal attenuation";"Oxidative Stress Induced Senescence";"NCAM signaling for neurite out-growth";"FCERI mediated MAPK activation";"Advanced glycosylation endproduct receptor signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF-independent MAPK1/3 activation";"ESR-mediated signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Negative feedback regulation of MAPK pathway";"RUNX2 regulates osteoblast differentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of FGFR1 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Growth hormone receptor signaling";"RSK activation";"ERK/MAPK targets";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Negative regulation of FGFR2 signaling";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Spry regulation of FGF signaling";"RHO GTPases Activate NADPH Oxidases";"RAF/MAP kinase cascade";"Activation of the AP-1 family of transcription factors";"Regulation of the apoptosome activity";"Signal transduction by L1";"MAP2K and MAPK activation";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"Signaling by BRAF and RAF fusions"
XP_050472849.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050489760.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122	"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050491841.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050483146.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050485604.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050474362.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050471367.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer"
XP_050477009.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050469603.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050484707.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050472105.1	58	Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5689901;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Metalloprotease DUBs";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Neddylation";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex"
XP_050469389.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050484020.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050490001.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_050476553.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050476677.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050488055.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050486790.1	7	MetaCyc: PWY-2541;Reactome: R-HSA-9022692;MetaCyc: PWY-6074;MetaCyc: PWY-7154;Reactome: R-HSA-191273;KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026	"Phytosterol biosynthesis (plants)";"Regulation of MECP2 expression and activity";"Zymosterol biosynthesis";"Ergosterol biosynthesis II";"Cholesterol biosynthesis";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)"
XP_050486391.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050490218.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050478232.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050494196.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050494144.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-174084	"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_050491439.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_050471684.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_050470330.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050469546.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050482165.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050473851.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52	"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series"
XP_050490658.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_050488870.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050495083.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050493120.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050484990.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050472472.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050482876.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050481902.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_050470956.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050482811.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050469777.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050480922.1	12	KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050491225.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_050480966.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_050485677.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050475661.1	11	KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-7586;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-3861	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Mannitol degradation II"
XP_050476790.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050479683.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050481196.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050479810.1	13	Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-422356	"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Ca2+ pathway";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion"
XP_050472614.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050470863.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050480932.1	12	KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Human papillomavirus infection";"NRAGE signals death through JNK";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_050478250.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_050493239.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050492895.1	6	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-204005	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport"
XP_050484262.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050492594.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_050479381.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050486623.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_050487751.1	52	Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-167287	"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery"
XP_050480126.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050491690.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050476758.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III"
XP_050491398.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050492290.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050481929.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050486395.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050481281.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050470816.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571	"mTOR signalling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation"
XP_050487748.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_050470530.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-975871	"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane"
XP_050475202.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_050470346.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050473566.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050476569.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050473912.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050476293.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050491131.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050472726.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050474232.1	10	Reactome: R-HSA-916853;KEGG: 00410+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;KEGG: 00640+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-6536;MetaCyc: PWY-6535	"Degradation of GABA";"beta-Alanine metabolism";"4-aminobutanoate degradation V";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"Propanoate metabolism";"Butanoate metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"4-aminobutanoate degradation I"
XP_050492373.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050491730.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050470609.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050486815.1	7	MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Purine metabolism"
XP_050472112.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050487124.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050493320.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050471227.1	11	Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108	"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Circadian Clock";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050488424.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050478296.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_050488598.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050474006.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050476905.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050492120.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_050475166.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050472246.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050470112.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050487845.1	14	KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-7124;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5723	"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Rubisco shunt"
XP_050471999.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050470823.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization"
XP_050496571.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium"
XP_050481168.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050481823.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_050492719.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050476297.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050482000.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050472884.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050488220.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050489089.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050483652.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050486712.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050479144.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050489907.1	4	KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801	"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion"
XP_050492385.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_050488146.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050469533.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050491579.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050482317.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050481482.1	16	Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557;Reactome: R-HSA-114604	"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT";"GPVI-mediated activation cascade"
XP_050488702.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050489466.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050482605.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_050470793.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050473000.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050497040.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050493671.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050479112.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050482411.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050473978.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050494295.1	23	Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-420092	"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Ca2+ pathway";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"Glucagon-type ligand receptors"
XP_050483924.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050482871.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050477818.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_050469695.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050474349.1	4	Reactome: R-HSA-4570464;Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-72163	"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"mRNA Splicing - Major Pathway"
XP_050483098.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050473193.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050482795.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050483348.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050478122.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050486524.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050470093.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_050476363.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_050479145.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_050482492.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050474106.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050485175.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050478879.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050483691.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-6807878	"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Kinesins";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"HCMV Early Events";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport"
XP_050481452.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050485609.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050472497.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050483798.1	10	Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation"
XP_050481249.1	9	KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822	"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)"
XP_050472806.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050491683.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050492795.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660	"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway"
XP_050480596.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357	"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1"
XP_050482799.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050471998.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050477589.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952	"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF activation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions"
XP_050485624.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_050487565.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050493105.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050487173.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050486555.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050473115.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_050487929.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050478242.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050479874.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6807505	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes"
XP_050491878.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050489470.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050486620.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_050492542.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050482630.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050485050.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050488147.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050491625.1	5	Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-171007	"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"p38MAPK events"
XP_050491132.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050489905.1	4	MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_050472084.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)"
XP_050483647.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050485938.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050487746.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050484449.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050471757.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway"
XP_050472999.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050487101.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_050493207.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050480376.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050490250.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050475274.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050473020.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050490890.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050471359.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050486272.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050475554.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050475028.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050481615.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050491489.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex"
XP_050475484.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720	"Hedgehog 'off' state";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_050479089.1	7	KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_050482862.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050471490.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_050471093.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050482268.1	3	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_050478571.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050474636.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050487719.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_050496433.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050485623.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050490795.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050471242.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050478658.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_050470090.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_050478099.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_050478422.1	8	MetaCyc: PWY-5738;MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;Reactome: R-HSA-6787639	"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-fucose biosynthesis"
XP_050476912.1	8	Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-8943724	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription"
XP_050479752.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_050473361.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050472244.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050495314.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_050483759.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_050472443.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_050496351.1	12	MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-7385;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13	"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism"
XP_050471399.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050481442.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050491402.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050491056.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050494012.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050470926.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050493352.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050493236.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050484467.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_050473860.1	8	Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Photosynthesis";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050474014.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines"
XP_050490824.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050481346.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_050483822.1	11	MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8055;Reactome: R-HSA-2029485;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053	"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II"
XP_050480725.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-6784531	"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus"
XP_050492989.1	12	KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932	"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction"
XP_050477021.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050474252.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050473642.1	3	Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_050480375.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050472805.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050479360.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050476053.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050484365.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050488982.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050480490.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050474654.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050483819.1	11	KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-2029485;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4	"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_050485020.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050470905.1	13	MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-7102;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7736;MetaCyc: PWY-7659	"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis"
XP_050477621.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-111932	"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Long-term potentiation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB"
XP_050477266.1	9	Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091	"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching"
XP_050479356.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050491584.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050490252.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050493504.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_050473925.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050482088.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050479126.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050474729.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050473435.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)"
XP_050492277.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_050493136.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050473036.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050478051.1	7	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-203641;Reactome: R-HSA-8856828;Reactome: R-HSA-373753;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"NOSTRIN mediated eNOS trafficking";"Clathrin-mediated endocytosis";"Nephrin family interactions";"EPHB-mediated forward signaling"
XP_050493952.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050496388.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050474123.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_050491187.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050490671.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050493540.1	14	KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416	"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_050489660.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296	"HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome"
XP_050476294.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050472782.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050487494.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation"
XP_050489500.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050496923.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050476749.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050471158.1	7	KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8	"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism"
XP_050473633.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243	"Synthesis of PC";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050478616.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Signaling by Hippo";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_050487626.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050493467.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_050493107.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050479335.1	26	Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-201722;Reactome: R-HSA-933541	"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"HATs acetylate histones";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation"
XP_050477643.1	9	Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3642279;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356	"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_050484236.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"