Protein

## Lalb_08546

Length
375 amino acids

### Protein family membership

- Nuclear translocator (IPR001067)

### Homologous superfamilies

1. Homologous superfamily
   72 - 125
   - Helix-loop-helix DNA-binding domain superfamily (IPR036638)
   158 - 266
   - PAS domain superfamily (IPR035965)

1 50 100 150 200 250 300 350 375

### Domains and repeats

1. Domain
   73 - 132
   - Myc-type, basic helix-loop-helix (bHLH) domain (IPR011598)
   145 - 215
   - PAS domain (IPR000014)
     - PAS fold (IPR013767)

1 50 100 150 200 250 300 350 375

### Detailed signature matches

1. IPR036638
   Helix-loop-helix DNA-binding domain superfamily
   1. G3DSA:4.10.28... (HLH)
      72 - 125
      GENE3D
      G3DSA:4.10.280.10 (HLH)
   2. SSF47459 (HLH, heli...)
      73 - 124
      SUPERFAMILY
      SSF47459 (HLH, helix-loop-helix DNA-binding domain)
2. IPR035965
   PAS domain superfamily
   1. SSF55785 (PYP-like ...)
      249 - 266
      SUPERFAMILY
      SSF55785 (PYP-like sensor domain (PAS domain))
      158 - 211
      SUPERFAMILY
      SSF55785 (PYP-like sensor domain (PAS domain))
3. IPR001067
   Nuclear translocator
   1. PR00785 (NCTRNSLOCATR)
      108 - 128
      PRINTS
      PR00785 (NCTRNSLOCATR)
      338 - 355
      PRINTS
      PR00785 (NCTRNSLOCATR)
      163 - 182
      PRINTS
      PR00785 (NCTRNSLOCATR)
      195 - 213
      PRINTS
      PR00785 (NCTRNSLOCATR)
      88 - 103
      PRINTS
      PR00785 (NCTRNSLOCATR)
4. IPR011598
   Myc-type, basic helix-loop-helix (bHLH) domain
   1. PS50888 (BHLH)
      73 - 126
      PROSITE profiles
      PS50888 (BHLH)
   2. cd00083 (HLH)
      75 - 125
      CDD
      cd00083 (HLH)
   3. SM00353 (finulus)
      79 - 132
      SMART
      SM00353 (finulus)
   4. PF00010 (HLH)
      75 - 123
      Pfam
      PF00010 (HLH)
5. IPR000014
   PAS domain
   1. PS50112 (PAS)
      161 - 209
      PROSITE profiles
      PS50112 (PAS)
   2. cd00130 (PAS)
      157 - 209
      CDD
      cd00130 (PAS)
   3. SM00091 (pas_2)
      145 - 215
      SMART
      SM00091 (pas_2)
   4. TIGR00229
      160 - 208
      TIGRFAMs
      TIGR00229 (TIGR00229)
6. IPR013767
   PAS fold
   1. PF00989 (PAS)
      157 - 209
      Pfam
      PF00989 (PAS)

no IPR
Unintegrated signatures

1. G3DSA:3.30.45...
   327 - 375
   GENE3D
   G3DSA:3.30.450.20 (G3DSA:3.30.450.20)
   158 - 324
   GENE3D
   G3DSA:3.30.450.20 (G3DSA:3.30.450.20)
2. PTHR23042 (CIRCADIA...)
   73 - 374
   PANTHER
   PTHR23042 (CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS)
3. PTHR23042:SF99 (FI1...)
   73 - 374
   PANTHER
   PTHR23042:SF99 (FI10506P-RELATED)

### Other features

1. Coil
   6 - 26
   COILS
   Coil (Coil)
2. mobidb-lite (disord...)
   216 - 256
   MobiDB Lite
   mobidb-lite (disorder_prediction)
3. mobidb-lite (Polyam...)
   242 - 256
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
4. mobidb-lite (Polar)
   216 - 241
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar

### Residue annotation

1. DNA binding region...
   75R
   DNA binding region
   75R, 81A, 82E, 83K, 85R, 109K, 112K
   CDD
   cd00083 (HLH)
   81A
   DNA binding region
   75R, 81A, 82E, 83K, 85R, 109K, 112K
   CDD
   cd00083 (HLH)
   82E
   DNA binding region
   75R, 81A, 82E, 83K, 85R, 109K, 112K
   CDD
   cd00083 (HLH)
   83K
   DNA binding region
   75R, 81A, 82E, 83K, 85R, 109K, 112K
   CDD
   cd00083 (HLH)
   85R
   DNA binding region
   75R, 81A, 82E, 83K, 85R, 109K, 112K
   CDD
   cd00083 (HLH)
   109K
   DNA binding region
   75R, 81A, 82E, 83K, 85R, 109K, 112K
   CDD
   cd00083 (HLH)
   112K
   DNA binding region
   75R, 81A, 82E, 83K, 85R, 109K, 112K
   CDD
   cd00083 (HLH)
2. E-box/N-box specif...
   82E
   E-box/N-box specificity site
   82E
   CDD
   cd00083 (HLH)

### GO term prediction

#### Biological Process

GO:0006355 regulation of transcription, DNA-templated

#### Molecular Function

GO:0003700 DNA-binding transcription factor activity
GO:0046983 protein dimerization activity

#### Cellular Component

GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm

Generated with InterProScan 5.45-80.0