Protein

## Lalb_13454

Length
1,212 amino acids

### Protein family membership

- Ribosome biogenesis protein Bms1/Tsr1 (IPR039761)

### Homologous superfamilies

1. Homologous superfamily
   82 - 194
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 200 400 600 800 1000 1212

### Domains and repeats

1. Domain
   47 - 260
   - Ribosome biogenesis protein Bms1, N-terminal (IPR037875)
2. Domain
   217 - 303
   - AARP2CN (IPR012948)
   748 - 1,047
   - Ribosome biogenesis protein BMS1/TSR1, C-terminal (IPR007034)

1 200 400 600 800 1000 1212

### Detailed signature matches

1. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      82 - 194
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
2. IPR039761
   Ribosome biogenesis protein Bms1/Tsr1
   1. PTHR12858 (RIBOSOME...)
      476 - 1,211
      PANTHER
      PTHR12858 (RIBOSOME BIOGENESIS PROTEIN)
      12 - 501
      PANTHER
      PTHR12858 (RIBOSOME BIOGENESIS PROTEIN)
3. IPR037875
   Ribosome biogenesis protein Bms1, N-terminal
   1. cd01882 (BMS1)
      47 - 260
      CDD
      cd01882 (BMS1)
4. IPR012948
   AARP2CN
   1. PF08142 (AARP2CN)
      217 - 302
      Pfam
      PF08142 (AARP2CN)
   2. SM00785 (aarp2cn2)
      217 - 303
      SMART
      SM00785 (aarp2cn2)
5. IPR007034
   Ribosome biogenesis protein BMS1/TSR1, C-terminal
   1. SM01362 (DUF663_2)
      748 - 1,046
      SMART
      SM01362 (DUF663_2)
   2. PF04950 (RIBIOP_C)
      761 - 1,047
      Pfam
      PF04950 (RIBIOP_C)

no IPR
Unintegrated signatures

1. PTHR12858:SF2 (RIBO...)
   476 - 1,211
   PANTHER
   PTHR12858:SF2 (RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG)
   12 - 501
   PANTHER
   PTHR12858:SF2 (RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG)

### Other features

1. Coil
   1,189 - 1,209
   COILS
   Coil (Coil)
   666 - 686
   COILS
   Coil (Coil)
   756 - 776
   COILS
   Coil (Coil)
   171 - 191
   COILS
   Coil (Coil)
   1,167 - 1,187
   COILS
   Coil (Coil)
2. mobidb-lite (disord...)
   413 - 612
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   1 - 42
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   735 - 758
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   1,185 - 1,212
   MobiDB Lite
   mobidb-lite (disorder_prediction)
3. mobidb-lite (Negati...)
   580 - 608
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Negative Polyelectrolyte
   418 - 456
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Negative Polyelectrolyte
4. mobidb-lite (Polyam...)
   739 - 758
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
   1,185 - 1,205
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
   1 - 16
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
5. mobidb-lite (Polar)
   541 - 556
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar

### Residue annotation

1. G1 box cd01882
   92G
   G1 box
   92G, 93P, 94P, 95K, 96V, 97G, 98K, 99S
   CDD
   cd01882 (BMS1)
   93P
   G1 box
   92G, 93P, 94P, 95K, 96V, 97G, 98K, 99S
   CDD
   cd01882 (BMS1)
   94P
   G1 box
   92G, 93P, 94P, 95K, 96V, 97G, 98K, 99S
   CDD
   cd01882 (BMS1)
   95K
   G1 box
   92G, 93P, 94P, 95K, 96V, 97G, 98K, 99S
   CDD
   cd01882 (BMS1)
   96V
   G1 box
   92G, 93P, 94P, 95K, 96V, 97G, 98K, 99S
   CDD
   cd01882 (BMS1)
   97G
   G1 box
   92G, 93P, 94P, 95K, 96V, 97G, 98K, 99S
   CDD
   cd01882 (BMS1)
   98K
   G1 box
   92G, 93P, 94P, 95K, 96V, 97G, 98K, 99S
   CDD
   cd01882 (BMS1)
   99S
   G1 box
   92G, 93P, 94P, 95K, 96V, 97G, 98K, 99S
   CDD
   cd01882 (BMS1)
2. GTP/Mg2+ binding s...
   95K
   GTP/Mg2+ binding site
   95K, 97G, 98K, 99S, 100L, 173D, 206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   97G
   GTP/Mg2+ binding site
   95K, 97G, 98K, 99S, 100L, 173D, 206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   98K
   GTP/Mg2+ binding site
   95K, 97G, 98K, 99S, 100L, 173D, 206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   99S
   GTP/Mg2+ binding site
   95K, 97G, 98K, 99S, 100L, 173D, 206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   100L
   GTP/Mg2+ binding site
   95K, 97G, 98K, 99S, 100L, 173D, 206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   173D
   GTP/Mg2+ binding site
   95K, 97G, 98K, 99S, 100L, 173D, 206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   206S
   GTP/Mg2+ binding site
   95K, 97G, 98K, 99S, 100L, 173D, 206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   207G
   GTP/Mg2+ binding site
   95K, 97G, 98K, 99S, 100L, 173D, 206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   208L
   GTP/Mg2+ binding site
   95K, 97G, 98K, 99S, 100L, 173D, 206S, 207G, 208L
   CDD
   cd01882 (BMS1)
3. Switch I region cd...
   109F
   Switch I region
   109F, 110V, 111R, 112Q, 113P, 114L, 115A, 116N
   CDD
   cd01882 (BMS1)
   110V
   Switch I region
   109F, 110V, 111R, 112Q, 113P, 114L, 115A, 116N
   CDD
   cd01882 (BMS1)
   111R
   Switch I region
   109F, 110V, 111R, 112Q, 113P, 114L, 115A, 116N
   CDD
   cd01882 (BMS1)
   112Q
   Switch I region
   109F, 110V, 111R, 112Q, 113P, 114L, 115A, 116N
   CDD
   cd01882 (BMS1)
   113P
   Switch I region
   109F, 110V, 111R, 112Q, 113P, 114L, 115A, 116N
   CDD
   cd01882 (BMS1)
   114L
   Switch I region
   109F, 110V, 111R, 112Q, 113P, 114L, 115A, 116N
   CDD
   cd01882 (BMS1)
   115A
   Switch I region
   109F, 110V, 111R, 112Q, 113P, 114L, 115A, 116N
   CDD
   cd01882 (BMS1)
   116N
   Switch I region
   109F, 110V, 111R, 112Q, 113P, 114L, 115A, 116N
   CDD
   cd01882 (BMS1)
4. G2 box cd01882
   113P
   G2 box
   113P
   CDD
   cd01882 (BMS1)
5. G3 box cd01882
   135E
   G3 box
   135E, 136C, 137N, 138N
   CDD
   cd01882 (BMS1)
   136C
   G3 box
   135E, 136C, 137N, 138N
   CDD
   cd01882 (BMS1)
   137N
   G3 box
   135E, 136C, 137N, 138N
   CDD
   cd01882 (BMS1)
   138N
   G3 box
   135E, 136C, 137N, 138N
   CDD
   cd01882 (BMS1)
6. Switch II region c...
   138N
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   139D
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   140I
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   141N
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   142C
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   143M
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   144I
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   145D
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   146I
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   147A
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   148K
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   149V
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
   150A
   Switch II region
   138N, 139D, 140I, 141N, 142C, 143M, 144I, 145D, 146I, 147A, 148K, 149V, 150A
   CDD
   cd01882 (BMS1)
7. G5 box cd01882
   206S
   G5 box
   206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   207G
   G5 box
   206S, 207G, 208L
   CDD
   cd01882 (BMS1)
   208L
   G5 box
   206S, 207G, 208L
   CDD
   cd01882 (BMS1)

### GO term prediction

#### Biological Process

GO:0042254 ribosome biogenesis

#### Molecular Function

GO:0005525 GTP binding

#### Cellular Component

GO:0005634 nucleus

Generated with InterProScan 5.45-80.0