Protein

## Lalb_01714

Length
315 amino acids

### Protein family membership

- Transcription factor TFIIB (IPR000812)

### Homologous superfamilies

1. Homologous superfamily
   114 - 206
   - Cyclin-like superfamily (IPR036915)
   208 - 314
   - Cyclin-like superfamily (IPR036915)

1 50 100 150 200 250 315

### Domains and repeats

1. Domain
   10 - 54
   - Zinc finger, TFIIB-type (IPR013137)
   113 - 199
   - Cyclin-like (IPR013763)
     - Transcription factor TFIIB, cyclin-like domain (IPR013150)
   212 - 293
   - Cyclin-like (IPR013763)
     - Transcription factor TFIIB, cyclin-like domain (IPR013150)

1 50 100 150 200 250 315

### Detailed signature matches

1. IPR036915
   Cyclin-like superfamily
   1. SSF47954 (Cyclin-like)
      114 - 206
      SUPERFAMILY
      SSF47954 (Cyclin-like)
      208 - 314
      SUPERFAMILY
      SSF47954 (Cyclin-like)
2. IPR000812
   Transcription factor TFIIB
   1. PTHR11618 (TRANSCRI...)
      8 - 310
      PANTHER
      PTHR11618 (TRANSCRIPTION INITIATION FACTOR IIB-RELATED)
   2. PR00685 (TIFACTORIIB)
      186 - 201
      PRINTS
      PR00685 (TIFACTORIIB)
      247 - 263
      PRINTS
      PR00685 (TIFACTORIIB)
      213 - 231
      PRINTS
      PR00685 (TIFACTORIIB)
      160 - 179
      PRINTS
      PR00685 (TIFACTORIIB)
      48 - 61
      PRINTS
      PR00685 (TIFACTORIIB)
      279 - 293
      PRINTS
      PR00685 (TIFACTORIIB)
      26 - 46
      PRINTS
      PR00685 (TIFACTORIIB)
      62 - 83
      PRINTS
      PR00685 (TIFACTORIIB)
3. IPR013137
   Zinc finger, TFIIB-type
   1. PS51134 (ZF_TFIIB)
      10 - 41
      PROSITE profiles
      PS51134 (ZF_TFIIB)
   2. PF08271 (TF_Zn_Ribbon)
      21 - 54
      Pfam
      PF08271 (TF_Zn_Ribbon)
4. IPR013763
   Cyclin-like
   1. SM00385 (cyclin_7)
      212 - 293
      SMART
      SM00385 (cyclin_7)
      118 - 199
      SMART
      SM00385 (cyclin_7)
   2. cd00043 (CYCLIN)
      212 - 292
      CDD
      cd00043 (CYCLIN)
      113 - 198
      CDD
      cd00043 (CYCLIN)
5. IPR013150
   Transcription factor TFIIB, cyclin-like domain
   1. PF00382 (TFIIB)
      120 - 190
      Pfam
      PF00382 (TFIIB)
      214 - 284
      Pfam
      PF00382 (TFIIB)
6. IPR023486
   Transcription factor TFIIB, conserved site
   1. PS00782 (TFIIB)
      246 - 261
      PROSITE patterns
      PS00782 (TFIIB)
      152 - 167
      PROSITE patterns
      PS00782 (TFIIB)

no IPR
Unintegrated signatures

1. G3DSA:1.10.47...
   209 - 314
   GENE3D
   G3DSA:1.10.472.10 (G3DSA:1.10.472.10)
   112 - 208
   GENE3D
   G3DSA:1.10.472.10 (G3DSA:1.10.472.10)
2. G3DSA:2.20.25.10
   2 - 58
   GENE3D
   G3DSA:2.20.25.10 (G3DSA:2.20.25.10)
3. PTHR11618:SF13 (TRA...)
   8 - 310
   PANTHER
   PTHR11618:SF13 (TRANSCRIPTION INITIATION FACTOR IIB)
4. SSF57783 (Zinc beta...)
   8 - 57
   SUPERFAMILY
   SSF57783 (Zinc beta-ribbon)

### Residue annotation

1. binding site 1 cd0...
   113L
   binding site 1
   113L, 119E, 120I, 122G, 123M, 145H, 155N, 156D
   CDD
   cd00043 (CYCLIN)
   119E
   binding site 1
   113L, 119E, 120I, 122G, 123M, 145H, 155N, 156D
   CDD
   cd00043 (CYCLIN)
   120I
   binding site 1
   113L, 119E, 120I, 122G, 123M, 145H, 155N, 156D
   CDD
   cd00043 (CYCLIN)
   122G
   binding site 1
   113L, 119E, 120I, 122G, 123M, 145H, 155N, 156D
   CDD
   cd00043 (CYCLIN)
   123M
   binding site 1
   113L, 119E, 120I, 122G, 123M, 145H, 155N, 156D
   CDD
   cd00043 (CYCLIN)
   145H
   binding site 1
   113L, 119E, 120I, 122G, 123M, 145H, 155N, 156D
   CDD
   cd00043 (CYCLIN)
   155N
   binding site 1
   113L, 119E, 120I, 122G, 123M, 145H, 155N, 156D
   CDD
   cd00043 (CYCLIN)
   156D
   binding site 1
   113L, 119E, 120I, 122G, 123M, 145H, 155N, 156D
   CDD
   cd00043 (CYCLIN)
2. binding site 2 cd0...
   258Y
   binding site 2
   258Y, 262Q, 269S, 284I, 287S, 288Y
   CDD
   cd00043 (CYCLIN)
   262Q
   binding site 2
   258Y, 262Q, 269S, 284I, 287S, 288Y
   CDD
   cd00043 (CYCLIN)
   269S
   binding site 2
   258Y, 262Q, 269S, 284I, 287S, 288Y
   CDD
   cd00043 (CYCLIN)
   284I
   binding site 2
   258Y, 262Q, 269S, 284I, 287S, 288Y
   CDD
   cd00043 (CYCLIN)
   287S
   binding site 2
   258Y, 262Q, 269S, 284I, 287S, 288Y
   CDD
   cd00043 (CYCLIN)
   288Y
   binding site 2
   258Y, 262Q, 269S, 284I, 287S, 288Y
   CDD
   cd00043 (CYCLIN)
3. binding site 2 cd0...
   164Y
   binding site 2
   164Y, 168R, 175T, 190I, 193C, 194F
   CDD
   cd00043 (CYCLIN)
   168R
   binding site 2
   164Y, 168R, 175T, 190I, 193C, 194F
   CDD
   cd00043 (CYCLIN)
   175T
   binding site 2
   164Y, 168R, 175T, 190I, 193C, 194F
   CDD
   cd00043 (CYCLIN)
   190I
   binding site 2
   164Y, 168R, 175T, 190I, 193C, 194F
   CDD
   cd00043 (CYCLIN)
   193C
   binding site 2
   164Y, 168R, 175T, 190I, 193C, 194F
   CDD
   cd00043 (CYCLIN)
   194F
   binding site 2
   164Y, 168R, 175T, 190I, 193C, 194F
   CDD
   cd00043 (CYCLIN)

### GO term prediction

#### Biological Process

GO:0006352 DNA-templated transcription, initiation
GO:0070897 transcription preinitiation complex assembly

#### Molecular Function

GO:0017025 TBP-class protein binding

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0