Protein

## Lalb_08955

Length
626 amino acids

### Protein family membership

None predicted.

### Homologous superfamilies

1. Homologous superfamily
   88 - 143
   - PAS domain superfamily (IPR035965)
   220 - 319
   - PAS domain superfamily (IPR035965)

1 100 200 300 400 500 626

### Domains and repeats

1. Domain
   3 - 56
   - Myc-type, basic helix-loop-helix (bHLH) domain (IPR011598)
   78 - 146
   - PAS domain (IPR000014)
   207 - 320
   - PAS domain (IPR000014)

1 100 200 300 400 500 626

### Detailed signature matches

1. IPR035965
   PAS domain superfamily
   1. SSF55785 (PYP-like ...)
      220 - 319
      SUPERFAMILY
      SSF55785 (PYP-like sensor domain (PAS domain))
      88 - 143
      SUPERFAMILY
      SSF55785 (PYP-like sensor domain (PAS domain))
2. IPR011598
   Myc-type, basic helix-loop-helix (bHLH) domain
   1. PS50888 (BHLH)
      3 - 56
      PROSITE profiles
      PS50888 (BHLH)
3. IPR000014
   PAS domain
   1. PS50112 (PAS)
      80 - 143
      PROSITE profiles
      PS50112 (PAS)
   2. SM00091 (pas_2)
      207 - 274
      SMART
      SM00091 (pas_2)
      78 - 146
      SMART
      SM00091 (pas_2)
   3. cd00130 (PAS)
      217 - 320
      CDD
      cd00130 (PAS)
      87 - 144
      CDD
      cd00130 (PAS)

no IPR
Unintegrated signatures

1. G3DSA:3.30.45...
   209 - 349
   GENE3D
   G3DSA:3.30.450.20 (G3DSA:3.30.450.20)
   88 - 199
   GENE3D
   G3DSA:3.30.450.20 (G3DSA:3.30.450.20)
2. PF14598 (PAS_11)
   218 - 326
   Pfam
   PF14598 (PAS_11)
3. PTHR23043 (HYPOXIA-...)
   2 - 616
   PANTHER
   PTHR23043 (HYPOXIA-INDUCIBLE FACTOR 1 ALPHA)
4. PTHR23043:SF24 (NEU...)
   2 - 616
   PANTHER
   PTHR23043:SF24 (NEURONAL PAS DOMAIN-CONTAINING PROTEIN 4)

### Other features

1. mobidb-lite (disord...)
   592 - 626
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   358 - 414
   MobiDB Lite
   mobidb-lite (disorder_prediction)
2. mobidb-lite (Polar)
   358 - 405
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar

### Residue annotation

1. putative active si...
   233I
   putative active site
   233I, 237A, 243Y, 256L, 257L, 258H, 259W, 287L, 292G
   CDD
   cd00130 (PAS)
   237A
   putative active site
   233I, 237A, 243Y, 256L, 257L, 258H, 259W, 287L, 292G
   CDD
   cd00130 (PAS)
   243Y
   putative active site
   233I, 237A, 243Y, 256L, 257L, 258H, 259W, 287L, 292G
   CDD
   cd00130 (PAS)
   256L
   putative active site
   233I, 237A, 243Y, 256L, 257L, 258H, 259W, 287L, 292G
   CDD
   cd00130 (PAS)
   257L
   putative active site
   233I, 237A, 243Y, 256L, 257L, 258H, 259W, 287L, 292G
   CDD
   cd00130 (PAS)
   258H
   putative active site
   233I, 237A, 243Y, 256L, 257L, 258H, 259W, 287L, 292G
   CDD
   cd00130 (PAS)
   259W
   putative active site
   233I, 237A, 243Y, 256L, 257L, 258H, 259W, 287L, 292G
   CDD
   cd00130 (PAS)
   287L
   putative active site
   233I, 237A, 243Y, 256L, 257L, 258H, 259W, 287L, 292G
   CDD
   cd00130 (PAS)
   292G
   putative active site
   233I, 237A, 243Y, 256L, 257L, 258H, 259W, 287L, 292G
   CDD
   cd00130 (PAS)
2. heme pocket cd00130
   253W
   heme pocket
   253W, 257L, 265A, 268K, 269H, 299C, 301L
   CDD
   cd00130 (PAS)
   257L
   heme pocket
   253W, 257L, 265A, 268K, 269H, 299C, 301L
   CDD
   cd00130 (PAS)
   265A
   heme pocket
   253W, 257L, 265A, 268K, 269H, 299C, 301L
   CDD
   cd00130 (PAS)
   268K
   heme pocket
   253W, 257L, 265A, 268K, 269H, 299C, 301L
   CDD
   cd00130 (PAS)
   269H
   heme pocket
   253W, 257L, 265A, 268K, 269H, 299C, 301L
   CDD
   cd00130 (PAS)
   299C
   heme pocket
   253W, 257L, 265A, 268K, 269H, 299C, 301L
   CDD
   cd00130 (PAS)
   301L
   heme pocket
   253W, 257L, 265A, 268K, 269H, 299C, 301L
   CDD
   cd00130 (PAS)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0046983 protein dimerization activity

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0