Protein

## Lalb_08960

Length
1,765 amino acids

### Protein family membership

- Triacylglycerol lipase family (IPR000734)

### Homologous superfamilies

1. Homologous superfamily
   3 - 116
   - Alpha/Beta hydrolase fold (IPR029058)
   117 - 363
   - Alpha/Beta hydrolase fold (IPR029058)
   356 - 612
   - Alpha/Beta hydrolase fold (IPR029058)
   610 - 795
   - Alpha/Beta hydrolase fold (IPR029058)
   796 - 995
   - Alpha/Beta hydrolase fold (IPR029058)
   996 - 1,245
   - Alpha/Beta hydrolase fold (IPR029058)
   1,246 - 1,420
   - Alpha/Beta hydrolase fold (IPR029058)
   1,428 - 1,699
   - Alpha/Beta hydrolase fold (IPR029058)
   1,700 - 1,764
   - Alpha/Beta hydrolase fold (IPR029058)

1 200 400 600 800 1000 1200 1400 1600 1765

### Domains and repeats

1. Domain
   8 - 99
   - Lipase/vitellogenin (IPR013818)
   135 - 346
   - Lipase/vitellogenin (IPR013818)
   379 - 592
   - Lipase/vitellogenin (IPR013818)
   612 - 791
   - Lipase/vitellogenin (IPR013818)
   797 - 979
   - Lipase/vitellogenin (IPR013818)
   992 - 1,253
   - Lipase/vitellogenin (IPR013818)
     - Lipase, N-terminal (IPR033906)
   1,247 - 1,393
   - Lipase/vitellogenin (IPR013818)
   1,444 - 1,670
   - Lipase/vitellogenin (IPR013818)
   1,701 - 1,760
   - Lipase/vitellogenin (IPR013818)

1 200 400 600 800 1000 1200 1400 1600 1765

### Detailed signature matches

1. IPR029058
   Alpha/Beta hydrolase fold
   1. SSF53474 (alpha/bet...)
      636 - 792
      SUPERFAMILY
      SSF53474 (alpha/beta-Hydrolases)
      1,012 - 1,240
      SUPERFAMILY
      SSF53474 (alpha/beta-Hydrolases)
      356 - 612
      SUPERFAMILY
      SSF53474 (alpha/beta-Hydrolases)
      1,445 - 1,699
      SUPERFAMILY
      SSF53474 (alpha/beta-Hydrolases)
      1,702 - 1,764
      SUPERFAMILY
      SSF53474 (alpha/beta-Hydrolases)
      8 - 111
      SUPERFAMILY
      SSF53474 (alpha/beta-Hydrolases)
      797 - 995
      SUPERFAMILY
      SSF53474 (alpha/beta-Hydrolases)
      133 - 361
      SUPERFAMILY
      SSF53474 (alpha/beta-Hydrolases)
      1,248 - 1,393
      SUPERFAMILY
      SSF53474 (alpha/beta-Hydrolases)
   2. G3DSA:3.40.50...
      1,700 - 1,764
      GENE3D
      G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
      117 - 363
      GENE3D
      G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
      796 - 995
      GENE3D
      G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
      1,246 - 1,420
      GENE3D
      G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
      1,428 - 1,699
      GENE3D
      G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
      364 - 609
      GENE3D
      G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
      996 - 1,245
      GENE3D
      G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
      610 - 795
      GENE3D
      G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
      3 - 116
      GENE3D
      G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
2. IPR000734
   Triacylglycerol lipase family
   1. PTHR11610 (LIPASE)
      1,004 - 1,242
      PANTHER
      PTHR11610 (LIPASE)
      795 - 990
      PANTHER
      PTHR11610 (LIPASE)
      623 - 791
      PANTHER
      PTHR11610 (LIPASE)
      1,244 - 1,397
      PANTHER
      PTHR11610 (LIPASE)
      8 - 109
      PANTHER
      PTHR11610 (LIPASE)
      378 - 610
      PANTHER
      PTHR11610 (LIPASE)
      1,430 - 1,700
      PANTHER
      PTHR11610 (LIPASE)
      132 - 364
      PANTHER
      PTHR11610 (LIPASE)
      1,701 - 1,758
      PANTHER
      PTHR11610 (LIPASE)
   2. PR00821 (TAGLIPASE)
      1,192 - 1,207
      PRINTS
      PR00821 (TAGLIPASE)
      1,006 - 1,025
      PRINTS
      PR00821 (TAGLIPASE)
      1,093 - 1,111
      PRINTS
      PR00821 (TAGLIPASE)
3. IPR013818
   Lipase/vitellogenin
   1. PF00151 (Lipase)
      1,444 - 1,670
      Pfam
      PF00151 (Lipase)
      1,701 - 1,760
      Pfam
      PF00151 (Lipase)
      379 - 592
      Pfam
      PF00151 (Lipase)
      1,004 - 1,229
      Pfam
      PF00151 (Lipase)
      612 - 791
      Pfam
      PF00151 (Lipase)
      1,247 - 1,393
      Pfam
      PF00151 (Lipase)
      135 - 346
      Pfam
      PF00151 (Lipase)
      8 - 99
      Pfam
      PF00151 (Lipase)
      797 - 979
      Pfam
      PF00151 (Lipase)
4. IPR033906
   Lipase, N-terminal
   1. cd00707 (Pancreat_l...)
      992 - 1,253
      CDD
      cd00707 (Pancreat_lipase_like)

### Residue annotation

1. nucleophilic elbow...
   1,098G
   nucleophilic elbow
   1,098G, 1,099H, 1,100S, 1,101L, 1,102G
   CDD
   cd00707 (Pancreat_lipase_like)
   1,099H
   nucleophilic elbow
   1,098G, 1,099H, 1,100S, 1,101L, 1,102G
   CDD
   cd00707 (Pancreat_lipase_like)
   1,100S
   nucleophilic elbow
   1,098G, 1,099H, 1,100S, 1,101L, 1,102G
   CDD
   cd00707 (Pancreat_lipase_like)
   1,101L
   nucleophilic elbow
   1,098G, 1,099H, 1,100S, 1,101L, 1,102G
   CDD
   cd00707 (Pancreat_lipase_like)
   1,102G
   nucleophilic elbow
   1,098G, 1,099H, 1,100S, 1,101L, 1,102G
   CDD
   cd00707 (Pancreat_lipase_like)
2. catalytic triad cd...
   1,100S
   catalytic triad
   1,100S, 1,124D, 1,194H
   CDD
   cd00707 (Pancreat_lipase_like)
   1,124D
   catalytic triad
   1,100S, 1,124D, 1,194H
   CDD
   cd00707 (Pancreat_lipase_like)
   1,194H
   catalytic triad
   1,100S, 1,124D, 1,194H
   CDD
   cd00707 (Pancreat_lipase_like)
3. active site flap/l...
   1,177C
   active site flap/lid
   1,177C, 1,181P, 1,191H, 1,192C
   CDD
   cd00707 (Pancreat_lipase_like)
   1,181P
   active site flap/lid
   1,177C, 1,181P, 1,191H, 1,192C
   CDD
   cd00707 (Pancreat_lipase_like)
   1,191H
   active site flap/lid
   1,177C, 1,181P, 1,191H, 1,192C
   CDD
   cd00707 (Pancreat_lipase_like)
   1,192C
   active site flap/lid
   1,177C, 1,181P, 1,191H, 1,192C
   CDD
   cd00707 (Pancreat_lipase_like)

### GO term prediction

#### Biological Process

GO:0006629 lipid metabolic process

#### Molecular Function

GO:0004806 triglyceride lipase activity

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0