Protein

## Lalb_08179

Length
627 amino acids

### Protein family membership

None predicted.

### Homologous superfamilies

1. Homologous superfamily
   89 - 328
   - Metallopeptidase, catalytic domain superfamily (IPR024079)

1 100 200 300 400 500 627

### Domains and repeats

1. Domain
   90 - 322
   - Peptidase M12B, ADAM/reprolysin (IPR001590)
     - Salivary gland reprolysin domain (IPR034030)
   333 - 396
   - ADAM cysteine-rich domain 2 (IPR041645)
2. Domain
   324 - 398
   - ADAM, cysteine-rich domain (IPR006586)

1 100 200 300 400 500 627

### Detailed signature matches

1. IPR024079
   Metallopeptidase, catalytic domain superfamily
   1. G3DSA:3.40.39... (C...)
      89 - 328
      GENE3D
      G3DSA:3.40.390.10 (Collagenase (Catalytic Domain))
2. IPR001590
   Peptidase M12B, ADAM/reprolysin
   1. PS50215 (ADAM_MEPRO)
      90 - 322
      PROSITE profiles
      PS50215 (ADAM_MEPRO)
3. IPR034030
   Salivary gland reprolysin domain
   1. cd04272 (ZnMc_saliv...)
      90 - 318
      CDD
      cd04272 (ZnMc_salivary_gland_MPs)
4. IPR006586
   ADAM, cysteine-rich domain
   1. SM00608 (acr)
      324 - 398
      SMART
      SM00608 (acr)
5. IPR041645
   ADAM cysteine-rich domain 2
   1. PF17771 (ADAM_CR_2)
      333 - 396
      Pfam
      PF17771 (ADAM_CR_2)

no IPR
Unintegrated signatures

1. PF13582 (Reprolysin_3)
   115 - 262
   Pfam
   PF13582 (Reprolysin_3)
2. PTHR13723 (ADAMTS ...)
   43 - 509
   PANTHER
   PTHR13723 (ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE)
3. PTHR13723:SF259
   43 - 509
   PANTHER
   PTHR13723:SF259 (PTHR13723:SF259)
4. SSF55486 (Metallopr...)
   90 - 322
   SUPERFAMILY
   SSF55486 (Metalloproteases ("zincins"), catalytic domain)

### Other features

1. mobidb-lite (disord...)
   567 - 586
   MobiDB Lite
   mobidb-lite (disorder_prediction)

### Residue annotation

1. active site cd04272
   251H
   active site
   251H, 252E, 255H, 257L, 258G, 259A, 261H
   CDD
   cd04272 (ZnMc_salivary_gland_MPs)
   252E
   active site
   251H, 252E, 255H, 257L, 258G, 259A, 261H
   CDD
   cd04272 (ZnMc_salivary_gland_MPs)
   255H
   active site
   251H, 252E, 255H, 257L, 258G, 259A, 261H
   CDD
   cd04272 (ZnMc_salivary_gland_MPs)
   257L
   active site
   251H, 252E, 255H, 257L, 258G, 259A, 261H
   CDD
   cd04272 (ZnMc_salivary_gland_MPs)
   258G
   active site
   251H, 252E, 255H, 257L, 258G, 259A, 261H
   CDD
   cd04272 (ZnMc_salivary_gland_MPs)
   259A
   active site
   251H, 252E, 255H, 257L, 258G, 259A, 261H
   CDD
   cd04272 (ZnMc_salivary_gland_MPs)
   261H
   active site
   251H, 252E, 255H, 257L, 258G, 259A, 261H
   CDD
   cd04272 (ZnMc_salivary_gland_MPs)

### GO term prediction

#### Biological Process

GO:0006508 proteolysis

#### Molecular Function

GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0