Protein

## Lalb_10719

Length
988 amino acids

### Protein family membership

- Ribosomal protein L34Ae (IPR008195)

### Homologous superfamilies

1. Homologous superfamily
   155 - 466
   - PAZ domain superfamily (IPR036085)
   659 - 892
   - Ribonuclease H superfamily (IPR036397)
   909 - 987
   - Ribosomal protein L34Ae superfamily (IPR038562)
2. Homologous superfamily
   445 - 893
   - Ribonuclease H-like superfamily (IPR012337)

1 100 200 300 400 500 600 700 800 900 988

### Domains and repeats

1. Domain
   315 - 451
   - PAZ domain (IPR003100)
   594 - 880
   - Piwi domain (IPR003165)

1 100 200 300 400 500 600 700 800 900 988

### Detailed signature matches

1. IPR036085
   PAZ domain superfamily
   1. SSF101690 (PAZ domain)
      155 - 466
      SUPERFAMILY
      SSF101690 (PAZ domain)
2. IPR012337
   Ribonuclease H-like superfamily
   1. SSF53098 (Ribonucle...)
      445 - 893
      SUPERFAMILY
      SSF53098 (Ribonuclease H-like)
3. IPR036397
   Ribonuclease H superfamily
   1. G3DSA:3.30.42...
      659 - 892
      GENE3D
      G3DSA:3.30.420.10 (G3DSA:3.30.420.10)
4. IPR038562
   Ribosomal protein L34Ae superfamily
   1. G3DSA:3.40.18...
      909 - 987
      GENE3D
      G3DSA:3.40.1800.40 (G3DSA:3.40.1800.40)
5. IPR008195
   Ribosomal protein L34Ae
   1. PR01250 (RIBOSOMALL34)
      916 - 926
      PRINTS
      PR01250 (RIBOSOMALL34)
      898 - 915
      PRINTS
      PR01250 (RIBOSOMALL34)
      936 - 958
      PRINTS
      PR01250 (RIBOSOMALL34)
   2. PF01199 (Ribosomal_...)
      891 - 966
      Pfam
      PF01199 (Ribosomal_L34e)
6. IPR003100
   PAZ domain
   1. PS50821 (PAZ)
      315 - 427
      PROSITE profiles
      PS50821 (PAZ)
   2. PF02170 (PAZ)
      318 - 447
      Pfam
      PF02170 (PAZ)
   3. SM00949 (PAZ_2_a_3)
      315 - 451
      SMART
      SM00949 (PAZ_2_a_3)
7. IPR003165
   Piwi domain
   1. SM00950 (Piwi_a_2)
      594 - 880
      SMART
      SM00950 (Piwi_a_2)
   2. PF02171 (Piwi)
      595 - 879
      Pfam
      PF02171 (Piwi)
   3. PS50822 (PIWI)
      594 - 880
      PROSITE profiles
      PS50822 (PIWI)

no IPR
Unintegrated signatures

1. G3DSA:2.170.2... (p...)
   314 - 435
   GENE3D
   G3DSA:2.170.260.10 (paz domain)
2. G3DSA:3.40.50...
   521 - 648
   GENE3D
   G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
3. PTHR22891 (EUKARYOT...)
   64 - 893
   PANTHER
   PTHR22891 (EUKARYOTIC TRANSLATION INITIATION FACTOR 2C)
4. PTHR22891:SF145 (PR...)
   64 - 893
   PANTHER
   PTHR22891:SF145 (PROTEIN AUBERGINE-RELATED)
5. cd02845 (PAZ_piwi_like)
   307 - 429
   CDD
   cd02845 (PAZ_piwi_like)
6. cd04658 (Piwi_piwi-...)
   437 - 877
   CDD
   cd04658 (Piwi_piwi-like_Euk)

### Other features

1. mobidb-lite (disord...)
   1 - 127
   MobiDB Lite
   mobidb-lite (disorder_prediction)
2. mobidb-lite (Polyam...)
   1 - 21
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
3. mobidb-lite (Polar)
   22 - 83
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar

### Residue annotation

1. nucleic acid-bindi...
   358D
   nucleic acid-binding interface
   358D, 371L, 379Y, 383Y, 401S, 416V, 418L
   CDD
   cd02845 (PAZ_piwi_like)
   371L
   nucleic acid-binding interface
   358D, 371L, 379Y, 383Y, 401S, 416V, 418L
   CDD
   cd02845 (PAZ_piwi_like)
   379Y
   nucleic acid-binding interface
   358D, 371L, 379Y, 383Y, 401S, 416V, 418L
   CDD
   cd02845 (PAZ_piwi_like)
   383Y
   nucleic acid-binding interface
   358D, 371L, 379Y, 383Y, 401S, 416V, 418L
   CDD
   cd02845 (PAZ_piwi_like)
   401S
   nucleic acid-binding interface
   358D, 371L, 379Y, 383Y, 401S, 416V, 418L
   CDD
   cd02845 (PAZ_piwi_like)
   416V
   nucleic acid-binding interface
   358D, 371L, 379Y, 383Y, 401S, 416V, 418L
   CDD
   cd02845 (PAZ_piwi_like)
   418L
   nucleic acid-binding interface
   358D, 371L, 379Y, 383Y, 401S, 416V, 418L
   CDD
   cd02845 (PAZ_piwi_like)
2. 5' RNA guide stran...
   607Y
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   611K
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   623Q
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   624V
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   625F
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   626L
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   629N
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   637I
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   640K
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   644Q
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   648K
   5' RNA guide strand anchoring site
   607Y, 611K, 623Q, 624V, 625F, 626L, 629N, 637I, 640K, 644Q, 648K
   CDD
   cd04658 (Piwi_piwi-like_Euk)
3. active site cd04658
   669D
   active site
   669D, 671C, 739D, 869H
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   671C
   active site
   669D, 671C, 739D, 869H
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   739D
   active site
   669D, 671C, 739D, 869H
   CDD
   cd04658 (Piwi_piwi-like_Euk)
   869H
   active site
   669D, 671C, 739D, 869H
   CDD
   cd04658 (Piwi_piwi-like_Euk)

### GO term prediction

#### Biological Process

GO:0006412 translation

#### Molecular Function

GO:0003676 nucleic acid binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding

#### Cellular Component

GO:0005840 ribosome

Generated with InterProScan 5.45-80.0