Protein

## Lalb_09960

Length
1,099 amino acids

### Protein family membership

- Vacuolar protein sorting-associated protein 11 (IPR016528)

### Homologous superfamilies

1. Homologous superfamily
   19 - 263
   - WD40/YVTN repeat-like-containing domain superfamily (IPR015943)
2. Homologous superfamily
   59 - 251
   - WD40-repeat-containing domain superfamily (IPR036322)
   373 - 586
   - Tetratricopeptide-like helical domain superfamily (IPR011990)
   814 - 903
   - Zinc finger, RING/FYVE/PHD-type (IPR013083)

1 100 200 300 400 500 600 700 800 900 1000 1099

### Domains and repeats

1. Domain
   830 - 868
   - Zinc finger, RING-type (IPR001841)
   872 - 915
   - Vacuolar protein sorting protein 11, C-terminal (IPR024763)
2. Repeat
   414 - 562
   - Clathrin, heavy chain/VPS, 7-fold repeat (IPR000547)
   573 - 744
   - Clathrin, heavy chain/VPS, 7-fold repeat (IPR000547)

1 100 200 300 400 500 600 700 800 900 1000 1099

### Detailed signature matches

1. IPR015943
   WD40/YVTN repeat-like-containing domain superfamily
   1. G3DSA:2.130.1...
      19 - 263
      GENE3D
      G3DSA:2.130.10.10 (G3DSA:2.130.10.10)
2. IPR036322
   WD40-repeat-containing domain superfamily
   1. SSF50978 (WD40 repe...)
      59 - 251
      SUPERFAMILY
      SSF50978 (WD40 repeat-like)
3. IPR011990
   Tetratricopeptide-like helical domain superfamily
   1. G3DSA:1.25.40.10
      373 - 586
      GENE3D
      G3DSA:1.25.40.10 (G3DSA:1.25.40.10)
4. IPR013083
   Zinc finger, RING/FYVE/PHD-type
   1. G3DSA:3.30.40.10 (Z...)
      814 - 903
      GENE3D
      G3DSA:3.30.40.10 (Zinc/RING finger domain)
5. IPR016528
   Vacuolar protein sorting-associated protein 11
   1. PIRSF007860 (Vps11)
      20 - 595
      PIRSF
      PIRSF007860 (Vps11)
      589 - 923
      PIRSF
      PIRSF007860 (Vps11)
   2. PTHR23323:SF24 (VAC...)
      23 - 918
      PANTHER
      PTHR23323:SF24 (VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG)
6. IPR001841
   Zinc finger, RING-type
   1. PS50089 (ZF_RING_2)
      830 - 868
      PROSITE profiles
      PS50089 (ZF_RING_2)
7. IPR024763
   Vacuolar protein sorting protein 11, C-terminal
   1. PF12451 (VPS11_C)
      872 - 915
      Pfam
      PF12451 (VPS11_C)
8. IPR000547
   Clathrin, heavy chain/VPS, 7-fold repeat
   1. PS50236 (CHCR)
      573 - 744
      PROSITE profiles
      PS50236 (CHCR)
      414 - 562
      PROSITE profiles
      PS50236 (CHCR)
   2. PF00637 (Clathrin)
      420 - 546
      Pfam
      PF00637 (Clathrin)

no IPR
Unintegrated signatures

1. PF13923 (zf-C3HC4_2)
   829 - 868
   Pfam
   PF13923 (zf-C3HC4_2)
2. PTHR23323 (VACUOLAR...)
   23 - 918
   PANTHER
   PTHR23323 (VACUOLAR MEMBRANE PROTEIN RELATED)
3. SSF57850 (RING/U-box)
   811 - 869
   SUPERFAMILY
   SSF57850 (RING/U-box)
4. cd16688 (RING-H2_Vps11)
   829 - 871
   CDD
   cd16688 (RING-H2_Vps11)

### Other features

1. mobidb-lite (disord...)
   1,015 - 1,099
   MobiDB Lite
   mobidb-lite (disorder_prediction)
2. mobidb-lite (Negati...)
   1,066 - 1,084
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Negative Polyelectrolyte
3. mobidb-lite (Polyam...)
   1,043 - 1,065
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
4. mobidb-lite (Polar)
   1,025 - 1,039
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar

### Residue annotation

1. Zn binding site cd...
   830C
   Zn binding site
   830C, 833C, 846C, 848H, 851H, 854C, 865C, 868C
   CDD
   cd16688 (RING-H2_Vps11)
   833C
   Zn binding site
   830C, 833C, 846C, 848H, 851H, 854C, 865C, 868C
   CDD
   cd16688 (RING-H2_Vps11)
   846C
   Zn binding site
   830C, 833C, 846C, 848H, 851H, 854C, 865C, 868C
   CDD
   cd16688 (RING-H2_Vps11)
   848H
   Zn binding site
   830C, 833C, 846C, 848H, 851H, 854C, 865C, 868C
   CDD
   cd16688 (RING-H2_Vps11)
   851H
   Zn binding site
   830C, 833C, 846C, 848H, 851H, 854C, 865C, 868C
   CDD
   cd16688 (RING-H2_Vps11)
   854C
   Zn binding site
   830C, 833C, 846C, 848H, 851H, 854C, 865C, 868C
   CDD
   cd16688 (RING-H2_Vps11)
   865C
   Zn binding site
   830C, 833C, 846C, 848H, 851H, 854C, 865C, 868C
   CDD
   cd16688 (RING-H2_Vps11)
   868C
   Zn binding site
   830C, 833C, 846C, 848H, 851H, 854C, 865C, 868C
   CDD
   cd16688 (RING-H2_Vps11)

### GO term prediction

#### Biological Process

GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport

#### Molecular Function

GO:0005515 protein binding

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0