Protein

## Lalb_13745

Length
1,301 amino acids

### Protein family membership

None predicted.

### Homologous superfamilies

1. Homologous superfamily
   73 - 387
   - ABC transporter type 1, transmembrane domain superfamily (IPR036640)
   404 - 632
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)
   662 - 1,013
   - ABC transporter type 1, transmembrane domain superfamily (IPR036640)
   1,017 - 1,256
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 200 400 600 800 1000 1200 1301

### Domains and repeats

1. Domain
   101 - 367
   - ABC transporter type 1, transmembrane domain (IPR011527)
   437 - 626
   - AAA+ ATPase domain (IPR003593)
   691 - 993
   - ABC transporter type 1, transmembrane domain (IPR011527)
   1,053 - 1,235
   - AAA+ ATPase domain (IPR003593)
2. Domain
   410 - 633
   - ABC transporter-like (IPR003439)
   1,027 - 1,258
   - ABC transporter-like (IPR003439)

1 200 400 600 800 1000 1200 1301

### Detailed signature matches

1. IPR036640
   ABC transporter type 1, transmembrane domain superfamily
   1. SSF90123 (ABC trans...)
      693 - 1,013
      SUPERFAMILY
      SSF90123 (ABC transporter transmembrane region)
      73 - 373
      SUPERFAMILY
      SSF90123 (ABC transporter transmembrane region)
   2. G3DSA:1.20.15...
      662 - 1,007
      GENE3D
      G3DSA:1.20.1560.10 (G3DSA:1.20.1560.10)
      79 - 387
      GENE3D
      G3DSA:1.20.1560.10 (G3DSA:1.20.1560.10)
2. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      1,017 - 1,256
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
      404 - 632
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
3. IPR011527
   ABC transporter type 1, transmembrane domain
   1. PS50929 (ABC_TM1F)
      101 - 367
      PROSITE profiles
      PS50929 (ABC_TM1F)
      691 - 993
      PROSITE profiles
      PS50929 (ABC_TM1F)
   2. PF00664 (ABC_membrane)
      101 - 363
      Pfam
      PF00664 (ABC_membrane)
      747 - 971
      Pfam
      PF00664 (ABC_membrane)
4. IPR003439
   ABC transporter-like
   1. PF00005 (ABC_tran)
      1,044 - 1,189
      Pfam
      PF00005 (ABC_tran)
      428 - 562
      Pfam
      PF00005 (ABC_tran)
   2. PS50893 (ABC_TRANSP...)
      1,027 - 1,258
      PROSITE profiles
      PS50893 (ABC_TRANSPORTER_2)
      410 - 633
      PROSITE profiles
      PS50893 (ABC_TRANSPORTER_2)
5. IPR003593
   AAA+ ATPase domain
   1. SM00382 (AAA_5)
      1,053 - 1,235
      SMART
      SM00382 (AAA_5)
      437 - 626
      SMART
      SM00382 (AAA_5)
6. IPR017871
   ABC transporter, conserved site
   1. PS00211 (ABC_TRANSP...)
      535 - 549
      PROSITE patterns
      PS00211 (ABC_TRANSPORTER_1)
      1,161 - 1,175
      PROSITE patterns
      PS00211 (ABC_TRANSPORTER_1)

no IPR
Unintegrated signatures

1. G3DSA:3.40.50...
   388 - 659
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   1,010 - 1,261
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
2. PTHR24223 (FAMILY N...)
   655 - 1,280
   PANTHER
   PTHR24223 (FAMILY NOT NAMED)
   5 - 121
   PANTHER
   PTHR24223 (FAMILY NOT NAMED)
   132 - 654
   PANTHER
   PTHR24223 (FAMILY NOT NAMED)
3. PTHR24223:SF334
   5 - 121
   PANTHER
   PTHR24223:SF334 (PTHR24223:SF334)
   655 - 1,280
   PANTHER
   PTHR24223:SF334 (PTHR24223:SF334)
   132 - 654
   PANTHER
   PTHR24223:SF334 (PTHR24223:SF334)
4. cd03244 (ABCC_MRP_d...)
   1,025 - 1,242
   CDD
   cd03244 (ABCC_MRP_domain2)
5. cd03250 (ABCC_MRP_d...)
   410 - 610
   CDD
   cd03250 (ABCC_MRP_domain1)
6. cd18580 (ABC_6TM_AB...)
   698 - 1,001
   CDD
   cd18580 (ABC_6TM_ABCC_D2)
7. cd18593 (ABC_6TM_MR...)
   95 - 385
   CDD
   cd18593 (ABC_6TM_MRP4_D1_like)

### Other features

1. mobidb-lite (disord...)
   638 - 672
   MobiDB Lite
   mobidb-lite (disorder_prediction)
2. mobidb-lite (Polar)
   638 - 658
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar

### Residue annotation

1. Walker A/P-loop cd...
   445G
   Walker A/P-loop
   445G, 446S, 447V, 448G, 449A, 450G, 451K, 452S
   CDD
   cd03250 (ABCC_MRP_domain1)
   446S
   Walker A/P-loop
   445G, 446S, 447V, 448G, 449A, 450G, 451K, 452S
   CDD
   cd03250 (ABCC_MRP_domain1)
   447V
   Walker A/P-loop
   445G, 446S, 447V, 448G, 449A, 450G, 451K, 452S
   CDD
   cd03250 (ABCC_MRP_domain1)
   448G
   Walker A/P-loop
   445G, 446S, 447V, 448G, 449A, 450G, 451K, 452S
   CDD
   cd03250 (ABCC_MRP_domain1)
   449A
   Walker A/P-loop
   445G, 446S, 447V, 448G, 449A, 450G, 451K, 452S
   CDD
   cd03250 (ABCC_MRP_domain1)
   450G
   Walker A/P-loop
   445G, 446S, 447V, 448G, 449A, 450G, 451K, 452S
   CDD
   cd03250 (ABCC_MRP_domain1)
   451K
   Walker A/P-loop
   445G, 446S, 447V, 448G, 449A, 450G, 451K, 452S
   CDD
   cd03250 (ABCC_MRP_domain1)
   452S
   Walker A/P-loop
   445G, 446S, 447V, 448G, 449A, 450G, 451K, 452S
   CDD
   cd03250 (ABCC_MRP_domain1)
2. ATP binding site c...
   448G
   ATP binding site
   448G, 449A, 451K, 452S, 453S, 480Q, 559D, 560D, 592H
   CDD
   cd03250 (ABCC_MRP_domain1)
   449A
   ATP binding site
   448G, 449A, 451K, 452S, 453S, 480Q, 559D, 560D, 592H
   CDD
   cd03250 (ABCC_MRP_domain1)
   451K
   ATP binding site
   448G, 449A, 451K, 452S, 453S, 480Q, 559D, 560D, 592H
   CDD
   cd03250 (ABCC_MRP_domain1)
   452S
   ATP binding site
   448G, 449A, 451K, 452S, 453S, 480Q, 559D, 560D, 592H
   CDD
   cd03250 (ABCC_MRP_domain1)
   453S
   ATP binding site
   448G, 449A, 451K, 452S, 453S, 480Q, 559D, 560D, 592H
   CDD
   cd03250 (ABCC_MRP_domain1)
   480Q
   ATP binding site
   448G, 449A, 451K, 452S, 453S, 480Q, 559D, 560D, 592H
   CDD
   cd03250 (ABCC_MRP_domain1)
   559D
   ATP binding site
   448G, 449A, 451K, 452S, 453S, 480Q, 559D, 560D, 592H
   CDD
   cd03250 (ABCC_MRP_domain1)
   560D
   ATP binding site
   448G, 449A, 451K, 452S, 453S, 480Q, 559D, 560D, 592H
   CDD
   cd03250 (ABCC_MRP_domain1)
   592H
   ATP binding site
   448G, 449A, 451K, 452S, 453S, 480Q, 559D, 560D, 592H
   CDD
   cd03250 (ABCC_MRP_domain1)
3. Q-loop/lid cd03250
   477Y
   Q-loop/lid
   477Y, 478A, 479S, 480Q
   CDD
   cd03250 (ABCC_MRP_domain1)
   478A
   Q-loop/lid
   477Y, 478A, 479S, 480Q
   CDD
   cd03250 (ABCC_MRP_domain1)
   479S
   Q-loop/lid
   477Y, 478A, 479S, 480Q
   CDD
   cd03250 (ABCC_MRP_domain1)
   480Q
   Q-loop/lid
   477Y, 478A, 479S, 480Q
   CDD
   cd03250 (ABCC_MRP_domain1)
4. ABC transporter si...
   535L
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
   536S
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
   537G
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
   538G
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
   539Q
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
   540R
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
   541A
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
   542R
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
   543I
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
   544N
   ABC transporter signature motif
   535L, 536S, 537G, 538G, 539Q, 540R, 541A, 542R, 543I, 544N
   CDD
   cd03250 (ABCC_MRP_domain1)
5. Walker B cd03250
   555I
   Walker B
   555I, 556Y, 557L, 558L, 559D, 560D
   CDD
   cd03250 (ABCC_MRP_domain1)
   556Y
   Walker B
   555I, 556Y, 557L, 558L, 559D, 560D
   CDD
   cd03250 (ABCC_MRP_domain1)
   557L
   Walker B
   555I, 556Y, 557L, 558L, 559D, 560D
   CDD
   cd03250 (ABCC_MRP_domain1)
   558L
   Walker B
   555I, 556Y, 557L, 558L, 559D, 560D
   CDD
   cd03250 (ABCC_MRP_domain1)
   559D
   Walker B
   555I, 556Y, 557L, 558L, 559D, 560D
   CDD
   cd03250 (ABCC_MRP_domain1)
   560D
   Walker B
   555I, 556Y, 557L, 558L, 559D, 560D
   CDD
   cd03250 (ABCC_MRP_domain1)
6. D-loop cd03250
   563S
   D-loop
   563S, 564A, 565V, 566D
   CDD
   cd03250 (ABCC_MRP_domain1)
   564A
   D-loop
   563S, 564A, 565V, 566D
   CDD
   cd03250 (ABCC_MRP_domain1)
   565V
   D-loop
   563S, 564A, 565V, 566D
   CDD
   cd03250 (ABCC_MRP_domain1)
   566D
   D-loop
   563S, 564A, 565V, 566D
   CDD
   cd03250 (ABCC_MRP_domain1)
7. H-loop/switch regi...
   588I
   H-loop/switch region
   588I, 589L, 590V, 591T, 592H, 593Q, 594V
   CDD
   cd03250 (ABCC_MRP_domain1)
   589L
   H-loop/switch region
   588I, 589L, 590V, 591T, 592H, 593Q, 594V
   CDD
   cd03250 (ABCC_MRP_domain1)
   590V
   H-loop/switch region
   588I, 589L, 590V, 591T, 592H, 593Q, 594V
   CDD
   cd03250 (ABCC_MRP_domain1)
   591T
   H-loop/switch region
   588I, 589L, 590V, 591T, 592H, 593Q, 594V
   CDD
   cd03250 (ABCC_MRP_domain1)
   592H
   H-loop/switch region
   588I, 589L, 590V, 591T, 592H, 593Q, 594V
   CDD
   cd03250 (ABCC_MRP_domain1)
   593Q
   H-loop/switch region
   588I, 589L, 590V, 591T, 592H, 593Q, 594V
   CDD
   cd03250 (ABCC_MRP_domain1)
   594V
   H-loop/switch region
   588I, 589L, 590V, 591T, 592H, 593Q, 594V
   CDD
   cd03250 (ABCC_MRP_domain1)

### GO term prediction

#### Biological Process

GO:0055085 transmembrane transport

#### Molecular Function

GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase-coupled transmembrane transporter activity

#### Cellular Component

GO:0016021 integral component of membrane

Generated with InterProScan 5.45-80.0