Protein

## Lalb_04500

Length
743 amino acids

### Protein family membership

- GPCR, family 2, secretin-like (IPR000832)

### Homologous superfamilies

1. Homologous superfamily
   38 - 182
   - Methuselah, N-terminal domain superfamily (IPR036272)

1 100 200 300 400 500 600 743

### Domains and repeats

1. Domain
   66 - 184
   - Methuselah, N-terminal domain (IPR010596)
   388 - 655
   - GPCR, family 2-like (IPR017981)

1 100 200 300 400 500 600 743

### Detailed signature matches

1. IPR036272
   Methuselah, N-terminal domain superfamily
   1. SSF63877 (Methusela...)
      38 - 182
      SUPERFAMILY
      SSF63877 (Methuselah ectodomain)
2. IPR000832
   GPCR, family 2, secretin-like
   1. PF00002 (7tm_2)
      394 - 647
      Pfam
      PF00002 (7tm_2)
3. IPR010596
   Methuselah, N-terminal domain
   1. PF06652 (Methuselah_N)
      66 - 184
      Pfam
      PF06652 (Methuselah_N)
4. IPR017981
   GPCR, family 2-like
   1. PS50261 (G_PROTEIN_...)
      388 - 655
      PROSITE profiles
      PS50261 (G_PROTEIN_RECEP_F2_4)

no IPR
Unintegrated signatures

1. G3DSA:1.20.10...
   378 - 654
   GENE3D
   G3DSA:1.20.1070.10 (G3DSA:1.20.1070.10)
   199 - 274
   GENE3D
   G3DSA:1.20.1070.10 (G3DSA:1.20.1070.10)
2. PTHR47154 (FAMILY N...)
   332 - 695
   PANTHER
   PTHR47154 (FAMILY NOT NAMED)
   65 - 257
   PANTHER
   PTHR47154 (FAMILY NOT NAMED)
3. SSF81321 (Family A ...)
   427 - 684
   SUPERFAMILY
   SSF81321 (Family A G protein-coupled receptor-like)
4. cd15039 (7tmB3_Meth...)
   395 - 666
   CDD
   cd15039 (7tmB3_Methuselah-like)

### Residue annotation

1. putative polypepti...
   396M
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   438F
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   441L
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   442H
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   445T
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   455I
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   462N
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   550K
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   551A
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   553F
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   555Y
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   616W
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   619E
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   633W
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)
   637D
   putative polypeptide ligand binding pocket
   396M, 438F, 441L, 442H, 445T, 455I, 462N, 550K, 551A, 553F, 555Y, 616W, 619E, 633W, 637D
   CDD
   cd15039 (7tmB3_Methuselah-like)

### GO term prediction

#### Biological Process

GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway

#### Molecular Function

GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity

#### Cellular Component

GO:0016021 integral component of membrane

Generated with InterProScan 5.45-80.0