Protein

## Lalb_13751

Length
489 amino acids

### Protein family membership

- G protein-coupled receptor, rhodopsin-like (IPR000276)
  - Dopamine receptor family (IPR000929)

### Homologous superfamilies

None predicted.

### Domains and repeats

1. Domain
   57 - 412
   - GPCR, rhodopsin-like, 7TM (IPR017452)

1 50 100 150 200 250 300 350 400 450 489

### Detailed signature matches

1. IPR000276
   G protein-coupled receptor, rhodopsin-like
   1. PS00237 (G_PROTEIN_...)
      126 - 142
      PROSITE patterns
      PS00237 (G_PROTEIN_RECEP_F1_1)
   2. SM01381 (7TM_GPCR_S...)
      51 - 427
      SMART
      SM01381 (7TM_GPCR_Srsx_2)
   3. PR00237 (GPCRRHODOPSN)
      156 - 177
      PRINTS
      PR00237 (GPCRRHODOPSN)
      120 - 142
      PRINTS
      PR00237 (GPCRRHODOPSN)
      42 - 66
      PRINTS
      PR00237 (GPCRRHODOPSN)
      394 - 420
      PRINTS
      PR00237 (GPCRRHODOPSN)
      357 - 381
      PRINTS
      PR00237 (GPCRRHODOPSN)
      210 - 233
      PRINTS
      PR00237 (GPCRRHODOPSN)
      75 - 96
      PRINTS
      PR00237 (GPCRRHODOPSN)
2. IPR000929
   Dopamine receptor family
   1. PR00242 (DOPAMINER)
      389 - 400
      PRINTS
      PR00242 (DOPAMINER)
      414 - 428
      PRINTS
      PR00242 (DOPAMINER)
      141 - 149
      PRINTS
      PR00242 (DOPAMINER)
      62 - 72
      PRINTS
      PR00242 (DOPAMINER)
3. IPR017452
   GPCR, rhodopsin-like, 7TM
   1. PF00001 (7tm_1)
      57 - 247
      Pfam
      PF00001 (7tm_1)
      263 - 412
      Pfam
      PF00001 (7tm_1)
   2. PS50262 (G_PROTEIN_...)
      57 - 412
      PROSITE profiles
      PS50262 (G_PROTEIN_RECEP_F1_2)

no IPR
Unintegrated signatures

1. G3DSA:1.20.10...
   270 - 431
   GENE3D
   G3DSA:1.20.1070.10 (G3DSA:1.20.1070.10)
   39 - 267
   GENE3D
   G3DSA:1.20.1070.10 (G3DSA:1.20.1070.10)
2. PTHR24247 (5-HYDROX...)
   46 - 252
   PANTHER
   PTHR24247 (5-HYDROXYTRYPTAMINE RECEPTOR)
   266 - 427
   PANTHER
   PTHR24247 (5-HYDROXYTRYPTAMINE RECEPTOR)
3. PTHR24247:SF202 (5-...)
   46 - 252
   PANTHER
   PTHR24247:SF202 (5-HYDROXYTRYPTAMINE RECEPTOR 6)
   266 - 427
   PANTHER
   PTHR24247:SF202 (5-HYDROXYTRYPTAMINE RECEPTOR 6)
4. SSF81321 (Family A ...)
   45 - 248
   SUPERFAMILY
   SSF81321 (Family A G protein-coupled receptor-like)
   353 - 441
   SUPERFAMILY
   SSF81321 (Family A G protein-coupled receptor-like)
   277 - 321
   SUPERFAMILY
   SSF81321 (Family A G protein-coupled receptor-like)
5. cd15065 (7tmA_Ap5-H...)
   45 - 423
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
6. cd15343 (7tmA_LPAR3...)
   258 - 413
   CDD
   cd15343 (7tmA_LPAR3_Edg7)

### Other features

1. mobidb-lite (disord...)
   1 - 25
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   330 - 349
   MobiDB Lite
   mobidb-lite (disorder_prediction)
2. mobidb-lite (Polar)
   1 - 15
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar

### Residue annotation

1. putative ligand bi...
   116W
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   120D
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   121V
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   124S
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   125T
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   203L
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   210A
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   213S
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   214S
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   217S
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   372W
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   375F
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   376F
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   379N
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   394F
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   398T
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)
   402Y
   putative ligand binding site
   116W, 120D, 121V, 124S, 125T, 203L, 210A, 213S, 214S, 217S, 372W, 375F, 376F, 379N, 394F, 398T, 402Y
   CDD
   cd15065 (7tmA_Ap5-HTB1-like)

### GO term prediction

#### Biological Process

GO:0007186 G protein-coupled receptor signaling pathway

#### Molecular Function

GO:0004930 G protein-coupled receptor activity

#### Cellular Component

GO:0016021 integral component of membrane

Generated with InterProScan 5.45-80.0