Protein

## Lalb_11349

Length
730 amino acids

### Protein family membership

None predicted.

### Homologous superfamilies

1. Homologous superfamily
   1 - 66
   - Mib/herc2 domain superfamily (IPR037252)
   67 - 119
   - Zinc finger, ZZ-type superfamily (IPR043145)
   130 - 217
   - Mib/herc2 domain superfamily (IPR037252)
   399 - 606
   - Ankyrin repeat-containing domain superfamily (IPR036770)

1 100 200 300 400 500 600 730

### Domains and repeats

1. Domain
   1 - 65
   - Mib-herc2 (IPR010606)
   70 - 118
   - Zinc finger, ZZ-type (IPR000433)
     - E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-type (IPR042056)
   134 - 212
   - Mib-herc2 (IPR010606)
   238 - 303
   - Mind bomb, SH3 repeat domain (IPR040847)
   322 - 386
   - Mind bomb, SH3 repeat domain (IPR040847)
   453 - 598
   - Ankyrin repeat-containing domain (IPR020683)
2. Repeat
   453 - 485
   - Ankyrin repeat (IPR002110)
   486 - 518
   - Ankyrin repeat (IPR002110)
   519 - 551
   - Ankyrin repeat (IPR002110)
   552 - 584
   - Ankyrin repeat (IPR002110)

1 100 200 300 400 500 600 730

### Detailed signature matches

1. IPR037252
   Mib/herc2 domain superfamily
   1. G3DSA:2.30.30...
      1 - 66
      GENE3D
      G3DSA:2.30.30.920 (G3DSA:2.30.30.920)
      130 - 217
      GENE3D
      G3DSA:2.30.30.920 (G3DSA:2.30.30.920)
   2. SSF159034 (Mib/herc...)
      136 - 211
      SUPERFAMILY
      SSF159034 (Mib/herc2 domain-like)
      4 - 64
      SUPERFAMILY
      SSF159034 (Mib/herc2 domain-like)
2. IPR043145
   Zinc finger, ZZ-type superfamily
   1. G3DSA:3.30.60.90
      67 - 119
      GENE3D
      G3DSA:3.30.60.90 (G3DSA:3.30.60.90)
3. IPR036770
   Ankyrin repeat-containing domain superfamily
   1. G3DSA:1.25.40.20
      399 - 523
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
      524 - 606
      GENE3D
      G3DSA:1.25.40.20 (G3DSA:1.25.40.20)
   2. SSF48403 (Ankyrin r...)
      425 - 598
      SUPERFAMILY
      SSF48403 (Ankyrin repeat)
4. IPR010606
   Mib-herc2
   1. PF06701 (MIB_HERC2)
      6 - 63
      Pfam
      PF06701 (MIB_HERC2)
      145 - 209
      Pfam
      PF06701 (MIB_HERC2)
   2. PS51416 (MIB_HERC2)
      1 - 65
      PROSITE profiles
      PS51416 (MIB_HERC2)
      134 - 212
      PROSITE profiles
      PS51416 (MIB_HERC2)
5. IPR000433
   Zinc finger, ZZ-type
   1. PF00569 (ZZ)
      70 - 113
      Pfam
      PF00569 (ZZ)
   2. PS01357 (ZF_ZZ_1)
      76 - 103
      PROSITE patterns
      PS01357 (ZF_ZZ_1)
   3. PS50135 (ZF_ZZ_2)
      70 - 117
      PROSITE profiles
      PS50135 (ZF_ZZ_2)
   4. SM00291 (zz_5)
      70 - 115
      SMART
      SM00291 (zz_5)
6. IPR042056
   E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-type
   1. cd02339 (ZZ_Mind_bomb)
      74 - 118
      CDD
      cd02339 (ZZ_Mind_bomb)
7. IPR040847
   Mind bomb, SH3 repeat domain
   1. PF18346 (SH3_15)
      238 - 303
      Pfam
      PF18346 (SH3_15)
      322 - 386
      Pfam
      PF18346 (SH3_15)
8. IPR020683
   Ankyrin repeat-containing domain
   1. PF12796 (Ank_2)
      502 - 583
      Pfam
      PF12796 (Ank_2)
   2. PS50297 (ANK_REP_RE...)
      453 - 598
      PROSITE profiles
      PS50297 (ANK_REP_REGION)
9. IPR002110
   Ankyrin repeat
   1. SM00248 (ANK_2a)
      453 - 482
      SMART
      SM00248 (ANK_2a)
      552 - 581
      SMART
      SM00248 (ANK_2a)
      519 - 548
      SMART
      SM00248 (ANK_2a)
      486 - 515
      SMART
      SM00248 (ANK_2a)
   2. PS50088 (ANK_REPEAT)
      552 - 584
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      486 - 518
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      519 - 551
      PROSITE profiles
      PS50088 (ANK_REPEAT)
      453 - 485
      PROSITE profiles
      PS50088 (ANK_REPEAT)
   3. PF00023 (Ank)
      454 - 484
      Pfam
      PF00023 (Ank)
   4. PR01415 (ANKYRIN)
      454 - 469
      PRINTS
      PR01415 (ANKYRIN)
      502 - 516
      PRINTS
      PR01415 (ANKYRIN)

no IPR
Unintegrated signatures

1. PTHR24202 (FAMILY N...)
   313 - 601
   PANTHER
   PTHR24202 (FAMILY NOT NAMED)
   1 - 311
   PANTHER
   PTHR24202 (FAMILY NOT NAMED)
2. SSF57850 (RING/U-box)
   54 - 131
   SUPERFAMILY
   SSF57850 (RING/U-box)

### Other features

1. mobidb-lite (disord...)
   598 - 730
   MobiDB Lite
   mobidb-lite (disorder_prediction)
2. mobidb-lite (Polyam...)
   635 - 649
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
   683 - 718
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
   598 - 614
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte

### Residue annotation

1. zinc cluster 1 cd0...
   76C
   zinc cluster 1
   76C, 79C, 100C, 103C
   CDD
   cd02339 (ZZ_Mind_bomb)
   79C
   zinc cluster 1
   76C, 79C, 100C, 103C
   CDD
   cd02339 (ZZ_Mind_bomb)
   100C
   zinc cluster 1
   76C, 79C, 100C, 103C
   CDD
   cd02339 (ZZ_Mind_bomb)
   103C
   zinc cluster 1
   76C, 79C, 100C, 103C
   CDD
   cd02339 (ZZ_Mind_bomb)
2. Zinc-binding sites...
   76C
   Zinc-binding sites
   76C, 79C, 91C, 94C, 100C, 103C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   79C
   Zinc-binding sites
   76C, 79C, 91C, 94C, 100C, 103C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   91C
   Zinc-binding sites
   76C, 79C, 91C, 94C, 100C, 103C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   94C
   Zinc-binding sites
   76C, 79C, 91C, 94C, 100C, 103C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   100C
   Zinc-binding sites
   76C, 79C, 91C, 94C, 100C, 103C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   103C
   Zinc-binding sites
   76C, 79C, 91C, 94C, 100C, 103C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   109H
   Zinc-binding sites
   76C, 79C, 91C, 94C, 100C, 103C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   113H
   Zinc-binding sites
   76C, 79C, 91C, 94C, 100C, 103C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
3. putative charged b...
   77D
   putative charged binding surface
   77D, 88R, 90K, 96N, 98D
   CDD
   cd02339 (ZZ_Mind_bomb)
   88R
   putative charged binding surface
   77D, 88R, 90K, 96N, 98D
   CDD
   cd02339 (ZZ_Mind_bomb)
   90K
   putative charged binding surface
   77D, 88R, 90K, 96N, 98D
   CDD
   cd02339 (ZZ_Mind_bomb)
   96N
   putative charged binding surface
   77D, 88R, 90K, 96N, 98D
   CDD
   cd02339 (ZZ_Mind_bomb)
   98D
   putative charged binding surface
   77D, 88R, 90K, 96N, 98D
   CDD
   cd02339 (ZZ_Mind_bomb)
4. putative hydrophob...
   89W
   putative hydrophobic binding surface
   89W, 104Y, 115F, 118I
   CDD
   cd02339 (ZZ_Mind_bomb)
   104Y
   putative hydrophobic binding surface
   89W, 104Y, 115F, 118I
   CDD
   cd02339 (ZZ_Mind_bomb)
   115F
   putative hydrophobic binding surface
   89W, 104Y, 115F, 118I
   CDD
   cd02339 (ZZ_Mind_bomb)
   118I
   putative hydrophobic binding surface
   89W, 104Y, 115F, 118I
   CDD
   cd02339 (ZZ_Mind_bomb)
5. zinc cluster 2 cd0...
   91C
   zinc cluster 2
   91C, 94C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   94C
   zinc cluster 2
   91C, 94C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   109H
   zinc cluster 2
   91C, 94C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)
   113H
   zinc cluster 2
   91C, 94C, 109H, 113H
   CDD
   cd02339 (ZZ_Mind_bomb)

### GO term prediction

#### Biological Process

GO:0016567 protein ubiquitination

#### Molecular Function

GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0