Protein

## Lalb_04478

Length
574 amino acids

### Protein family membership

None predicted.

### Homologous superfamilies

1. Homologous superfamily
   203 - 481
   - P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 100 200 300 400 500 574

### Domains and repeats

1. Domain
   135 - 163
   - RNA helicase, DEAD-box type, Q motif (IPR014014)
   355 - 505
   - Helicase, C-terminal (IPR001650)
2. Domain
   154 - 359
   - Helicase superfamily 1/2, ATP-binding domain (IPR014001)
     - DEAD/DEAH box helicase domain (IPR011545)

1 100 200 300 400 500 574

### Detailed signature matches

1. IPR027417
   P-loop containing nucleoside triphosphate hydrolase
   1. SSF52540 (P-loop co...)
      203 - 481
      SUPERFAMILY
      SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
2. IPR014014
   RNA helicase, DEAD-box type, Q motif
   1. PS51195 (Q_MOTIF)
      135 - 163
      PROSITE profiles
      PS51195 (Q_MOTIF)
3. IPR014001
   Helicase superfamily 1/2, ATP-binding domain
   1. PS51192 (HELICASE_A...)
      166 - 344
      PROSITE profiles
      PS51192 (HELICASE_ATP_BIND_1)
   2. SM00487 (ultradead3)
      154 - 359
      SMART
      SM00487 (ultradead3)
4. IPR011545
   DEAD/DEAH box helicase domain
   1. PF00270 (DEAD)
      159 - 331
      Pfam
      PF00270 (DEAD)
5. IPR001650
   Helicase, C-terminal
   1. PS51194 (HELICASE_CTER)
      355 - 505
      PROSITE profiles
      PS51194 (HELICASE_CTER)
   2. SM00490 (helicmild6)
      385 - 466
      SMART
      SM00490 (helicmild6)
   3. PF00271 (Helicase_C)
      379 - 466
      Pfam
      PF00271 (Helicase_C)
6. IPR000629
   ATP-dependent RNA helicase DEAD-box, conserved site
   1. PS00039 (DEAD_ATP_H...)
      286 - 294
      PROSITE patterns
      PS00039 (DEAD_ATP_HELICASE)

no IPR
Unintegrated signatures

1. G3DSA:3.40.50...
   108 - 351
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
   352 - 572
   GENE3D
   G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
2. PTHR24031 (RNA HELI...)
   56 - 497
   PANTHER
   PTHR24031 (RNA HELICASE)
3. PTHR24031:SF25 (ATP...)
   56 - 497
   PANTHER
   PTHR24031:SF25 (ATP-DEPENDENT RNA HELICASE DDX46-RELATED)
4. cd17957 (DEADc_DDX52)
   146 - 347
   CDD
   cd17957 (DEADc_DDX52)
5. cd18787 (SF2_C_DEAD)
   356 - 475
   CDD
   cd18787 (SF2_C_DEAD)

### Other features

1. Coil
   96 - 116
   COILS
   Coil (Coil)
   370 - 390
   COILS
   Coil (Coil)
2. mobidb-lite (disord...)
   526 - 574
   MobiDB Lite
   mobidb-lite (disorder_prediction)

### Residue annotation

1. ATP binding site c...
   155Y
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   157H
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   158P
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   159T
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   162Q
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   180P
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   181T
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   182G
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   183S
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   184G
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   185K
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   186T
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   187A
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
   288D
   ATP binding site
   155Y, 157H, 158P, 159T, 162Q, 180P, 181T, 182G, 183S, 184G, 185K, 186T, 187A, 288D
   CDD
   cd17957 (DEADc_DDX52)
2. DEAD box helicase ...
   288D
   DEAD box helicase motif
   288D, 289E, 290A, 291D
   CDD
   cd17957 (DEADc_DDX52)
   289E
   DEAD box helicase motif
   288D, 289E, 290A, 291D
   CDD
   cd17957 (DEADc_DDX52)
   290A
   DEAD box helicase motif
   288D, 289E, 290A, 291D
   CDD
   cd17957 (DEADc_DDX52)
   291D
   DEAD box helicase motif
   288D, 289E, 290A, 291D
   CDD
   cd17957 (DEADc_DDX52)
3. ATP binding site c...
   434G
   ATP binding site
   434G, 436D, 461R, 464R, 465A
   CDD
   cd18787 (SF2_C_DEAD)
   436D
   ATP binding site
   434G, 436D, 461R, 464R, 465A
   CDD
   cd18787 (SF2_C_DEAD)
   461R
   ATP binding site
   434G, 436D, 461R, 464R, 465A
   CDD
   cd18787 (SF2_C_DEAD)
   464R
   ATP binding site
   434G, 436D, 461R, 464R, 465A
   CDD
   cd18787 (SF2_C_DEAD)
   465A
   ATP binding site
   434G, 436D, 461R, 464R, 465A
   CDD
   cd18787 (SF2_C_DEAD)

### GO term prediction

#### Biological Process

None predicted.

#### Molecular Function

GO:0003676 nucleic acid binding
GO:0005524 ATP binding

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0