Protein

## Lalb_05142

Length
570 amino acids

### Protein family membership

- E3 ubiquitin-protein ligase synoviolin/Hrd1 (IPR032832)

### Homologous superfamilies

1. Homologous superfamily
   263 - 339
   - Zinc finger, RING/FYVE/PHD-type (IPR013083)

1 100 200 300 400 500 570

### Domains and repeats

1. Domain
   289 - 329
   - Zinc finger, RING-type (IPR001841)

1 100 200 300 400 500 570

### Detailed signature matches

1. IPR013083
   Zinc finger, RING/FYVE/PHD-type
   1. G3DSA:3.30.40.10 (Z...)
      263 - 339
      GENE3D
      G3DSA:3.30.40.10 (Zinc/RING finger domain)
2. IPR032832
   E3 ubiquitin-protein ligase synoviolin/Hrd1
   1. PTHR22763:SF173 (E3...)
      1 - 396
      PANTHER
      PTHR22763:SF173 (E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN)
3. IPR001841
   Zinc finger, RING-type
   1. SM00184 (ring_2)
      290 - 328
      SMART
      SM00184 (ring_2)
   2. PF13639 (zf-RING_2)
      289 - 329
      Pfam
      PF13639 (zf-RING_2)
   3. PS50089 (ZF_RING_2)
      290 - 329
      PROSITE profiles
      PS50089 (ZF_RING_2)

no IPR
Unintegrated signatures

1. PTHR22763 (RING ZIN...)
   1 - 396
   PANTHER
   PTHR22763 (RING ZINC FINGER PROTEIN)
2. SSF57850 (RING/U-box)
   270 - 338
   SUPERFAMILY
   SSF57850 (RING/U-box)
3. cd16479 (RING-H2_sy...)
   287 - 329
   CDD
   cd16479 (RING-H2_synoviolin)

### Other features

1. mobidb-lite (disord...)
   485 - 570
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   380 - 433
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   339 - 362
   MobiDB Lite
   mobidb-lite (disorder_prediction)
2. mobidb-lite (Polyam...)
   546 - 560
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
3. mobidb-lite (Polar)
   485 - 545
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar
   339 - 353
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar
   388 - 411
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar

### Residue annotation

1. Zn binding site cd...
   290C
   Zn binding site
   290C, 293C, 306C, 308H, 311H, 314C, 325C, 328C
   CDD
   cd16479 (RING-H2_synoviolin)
   293C
   Zn binding site
   290C, 293C, 306C, 308H, 311H, 314C, 325C, 328C
   CDD
   cd16479 (RING-H2_synoviolin)
   306C
   Zn binding site
   290C, 293C, 306C, 308H, 311H, 314C, 325C, 328C
   CDD
   cd16479 (RING-H2_synoviolin)
   308H
   Zn binding site
   290C, 293C, 306C, 308H, 311H, 314C, 325C, 328C
   CDD
   cd16479 (RING-H2_synoviolin)
   311H
   Zn binding site
   290C, 293C, 306C, 308H, 311H, 314C, 325C, 328C
   CDD
   cd16479 (RING-H2_synoviolin)
   314C
   Zn binding site
   290C, 293C, 306C, 308H, 311H, 314C, 325C, 328C
   CDD
   cd16479 (RING-H2_synoviolin)
   325C
   Zn binding site
   290C, 293C, 306C, 308H, 311H, 314C, 325C, 328C
   CDD
   cd16479 (RING-H2_synoviolin)
   328C
   Zn binding site
   290C, 293C, 306C, 308H, 311H, 314C, 325C, 328C
   CDD
   cd16479 (RING-H2_synoviolin)

### GO term prediction

#### Biological Process

GO:0016567 protein ubiquitination
GO:0030433 ubiquitin-dependent ERAD pathway

#### Molecular Function

GO:0061630 ubiquitin protein ligase activity

#### Cellular Component

GO:0000836 Hrd1p ubiquitin ligase complex

Generated with InterProScan 5.45-80.0