Protein

## Lalb_04484

Length
476 amino acids

### Protein family membership

- Protein phosphatase 2C family (IPR015655)

### Homologous superfamilies

1. Homologous superfamily
   35 - 473
   - PPM-type phosphatase domain superfamily (IPR036457)

1 50 100 150 200 250 300 350 400 450 476

### Domains and repeats

1. Domain
   53 - 466
   - PPM-type phosphatase domain (IPR001932)

1 50 100 150 200 250 300 350 400 450 476

### Detailed signature matches

1. IPR036457
   PPM-type phosphatase domain superfamily
   1. G3DSA:3.60.40.10 (P...)
      35 - 473
      GENE3D
      G3DSA:3.60.40.10 (Phosphatase 2c; Domain 1)
   2. SSF81606 (PP2C-like)
      417 - 467
      SUPERFAMILY
      SSF81606 (PP2C-like)
      60 - 132
      SUPERFAMILY
      SSF81606 (PP2C-like)
      180 - 384
      SUPERFAMILY
      SSF81606 (PP2C-like)
2. IPR015655
   Protein phosphatase 2C family
   1. PTHR13832 (PROTEIN ...)
      35 - 471
      PANTHER
      PTHR13832 (PROTEIN PHOSPHATASE 2C)
3. IPR001932
   PPM-type phosphatase domain
   1. SM00332 (PP2C_4)
      53 - 464
      SMART
      SM00332 (PP2C_4)
   2. cd00143 (PP2Cc)
      64 - 382
      CDD
      cd00143 (PP2Cc)
   3. PF00481 (PP2C)
      155 - 382
      Pfam
      PF00481 (PP2C)
   4. PS51746 (PPM_2)
      64 - 466
      PROSITE profiles
      PS51746 (PPM_2)
4. IPR000222
   PPM-type phosphatase, divalent cation binding
   1. PS01032 (PPM_1)
      94 - 102
      PROSITE patterns
      PS01032 (PPM_1)

no IPR
Unintegrated signatures

1. PTHR13832:SF343 ([P...)
   35 - 471
   PANTHER
   PTHR13832:SF343 ([PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL)

### Residue annotation

1. Active site cd00143
   75N
   Active site
   75N, 79E, 80D, 99D, 100G, 101H, 360D
   CDD
   cd00143 (PP2Cc)
   79E
   Active site
   75N, 79E, 80D, 99D, 100G, 101H, 360D
   CDD
   cd00143 (PP2Cc)
   80D
   Active site
   75N, 79E, 80D, 99D, 100G, 101H, 360D
   CDD
   cd00143 (PP2Cc)
   99D
   Active site
   75N, 79E, 80D, 99D, 100G, 101H, 360D
   CDD
   cd00143 (PP2Cc)
   100G
   Active site
   75N, 79E, 80D, 99D, 100G, 101H, 360D
   CDD
   cd00143 (PP2Cc)
   101H
   Active site
   75N, 79E, 80D, 99D, 100G, 101H, 360D
   CDD
   cd00143 (PP2Cc)
   360D
   Active site
   75N, 79E, 80D, 99D, 100G, 101H, 360D
   CDD
   cd00143 (PP2Cc)

### GO term prediction

#### Biological Process

GO:0006470 protein dephosphorylation

#### Molecular Function

GO:0003824 catalytic activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0