Protein

## Lalb_04493

Length
417 amino acids

### Protein family membership

- Actin family (IPR004000)
  - Actin-related protein 3 (IPR015623)

### Homologous superfamilies

1. Homologous superfamily
   5 - 155
   - ATPase, nucleotide binding domain (IPR043129)
   162 - 413
   - ATPase, nucleotide binding domain (IPR043129)

1 50 100 150 200 250 300 350 417

### Domains and repeats

None predicted.

### Detailed signature matches

1. IPR043129
   ATPase, nucleotide binding domain
   1. SSF53067 (Actin-lik...)
      5 - 155
      SUPERFAMILY
      SSF53067 (Actin-like ATPase domain)
      162 - 413
      SUPERFAMILY
      SSF53067 (Actin-like ATPase domain)
2. IPR004000
   Actin family
   1. SM00268 (actin_3)
      5 - 412
      SMART
      SM00268 (actin_3)
   2. PTHR11937 (ACTIN)
      4 - 408
      PANTHER
      PTHR11937 (ACTIN)
   3. PF00022 (Actin)
      6 - 408
      Pfam
      PF00022 (Actin)
3. IPR015623
   Actin-related protein 3
   1. PTHR11937:SF170 (AC...)
      4 - 408
      PANTHER
      PTHR11937:SF170 (ACTIN-RELATED PROTEIN 3B-RELATED)
4. IPR020902
   Actin/actin-like conserved site
   1. PS01132 (ACTINS_ACT...)
      111 - 123
      PROSITE patterns
      PS01132 (ACTINS_ACT_LIKE)

no IPR
Unintegrated signatures

1. G3DSA:3.30.42...
   300 - 385
   GENE3D
   G3DSA:3.30.420.40 (G3DSA:3.30.420.40)
   145 - 201
   GENE3D
   G3DSA:3.30.420.40 (G3DSA:3.30.420.40)
   386 - 404
   GENE3D
   G3DSA:3.30.420.40 (G3DSA:3.30.420.40)
   9 - 144
   GENE3D
   G3DSA:3.30.420.40 (G3DSA:3.30.420.40)
2. G3DSA:3.90.64... (A...)
   202 - 299
   GENE3D
   G3DSA:3.90.640.10 (Actin; Chain A)
3. cd00012 (NBD_sugar-...)
   9 - 196
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)

### Residue annotation

1. nucleotide binding...
   11D
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   12V
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   13G
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   14T
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   16Y
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   18K
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   144Q
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   169D
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   170S
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   171G
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)
   172D
   nucleotide binding site
   11D, 12V, 13G, 14T, 16Y, 18K, 144Q, 169D, 170S, 171G, 172D
   CDD
   cd00012 (NBD_sugar-kinase_HSP70_actin)

### GO term prediction

#### Biological Process

GO:0007015 actin filament organization
GO:0034314 Arp2/3 complex-mediated actin nucleation

#### Molecular Function

GO:0005524 ATP binding

#### Cellular Component

GO:0005885 Arp2/3 protein complex

Generated with InterProScan 5.45-80.0