Protein

## Lalb_05127

Length
511 amino acids

### Protein family membership

- MRG (IPR008676)

### Homologous superfamilies

1. Homologous superfamily
   3 - 116
   - Chromo-like domain superfamily (IPR016197)
   190 - 325
   - MRG, C-terminal domain superfamily (IPR038217)
   413 - 508
   - MRG, C-terminal domain superfamily (IPR038217)

1 50 100 150 200 250 300 350 400 450 511

### Domains and repeats

1. Domain
   33 - 90
   - Chromo/chromo shadow domain (IPR000953)
   186 - 509
   - MRG domain (IPR026541)

1 50 100 150 200 250 300 350 400 450 511

### Detailed signature matches

1. IPR016197
   Chromo-like domain superfamily
   1. SSF54160 (Chromo do...)
      3 - 116
      SUPERFAMILY
      SSF54160 (Chromo domain-like)
2. IPR038217
   MRG, C-terminal domain superfamily
   1. G3DSA:1.10.27...
      190 - 325
      GENE3D
      G3DSA:1.10.274.30 (G3DSA:1.10.274.30)
      413 - 508
      GENE3D
      G3DSA:1.10.274.30 (G3DSA:1.10.274.30)
3. IPR008676
   MRG
   1. PTHR10880 (MORTALIT...)
      6 - 505
      PANTHER
      PTHR10880 (MORTALITY FACTOR 4-LIKE PROTEIN)
4. IPR000953
   Chromo/chromo shadow domain
   1. SM00298 (chromo_7)
      33 - 90
      SMART
      SM00298 (chromo_7)
5. IPR026541
   MRG domain
   1. PF05712 (MRG)
      186 - 498
      Pfam
      PF05712 (MRG)
   2. PS51640 (MRG)
      189 - 509
      PROSITE profiles
      PS51640 (MRG)

no IPR
Unintegrated signatures

1. G3DSA:2.30.30...
   1 - 92
   GENE3D
   G3DSA:2.30.30.140 (G3DSA:2.30.30.140)
2. PTHR10880:SF15 (MSL...)
   6 - 505
   PANTHER
   PTHR10880:SF15 (MSL COMPLEX SUBUNIT 3)
3. cd18983 (CBD_MSL3_like)
   15 - 81
   CDD
   cd18983 (CBD_MSL3_like)

### Other features

1. Coil
   73 - 93
   COILS
   Coil (Coil)
2. mobidb-lite (disord...)
   105 - 191
   MobiDB Lite
   mobidb-lite (disorder_prediction)
3. mobidb-lite (Negati...)
   155 - 175
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Negative Polyelectrolyte
4. mobidb-lite (Polyam...)
   109 - 128
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polyampholyte
5. mobidb-lite (Polar)
   130 - 147
   MobiDB Lite
   mobidb-lite (disorder_prediction)
   Feature: Polar

### Residue annotation

1. putative peptide b...
   21E
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   22P
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   31Y
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   32D
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   33S
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   34K
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   54I
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   56F
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   57Q
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   58G
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   59W
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   63W
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   65R
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   66C
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   67V
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   68T
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   70E
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   71Y
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   72V
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   75D
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
   76T
   putative peptide binding site
   21E, 22P, 31Y, 32D, 33S, 34K, 54I, 56F, 57Q, 58G, 59W, 63W, 65R, 66C, 67V, 68T, 70E, 71Y, 72V, 75D, 76T
   CDD
   cd18983 (CBD_MSL3_like)
2. putative methylate...
   31Y
   putative methylated histone tail binding site
   31Y, 56F, 59W, 63W
   CDD
   cd18983 (CBD_MSL3_like)
   56F
   putative methylated histone tail binding site
   31Y, 56F, 59W, 63W
   CDD
   cd18983 (CBD_MSL3_like)
   59W
   putative methylated histone tail binding site
   31Y, 56F, 59W, 63W
   CDD
   cd18983 (CBD_MSL3_like)
   63W
   putative methylated histone tail binding site
   31Y, 56F, 59W, 63W
   CDD
   cd18983 (CBD_MSL3_like)
3. putative RNA bindi...
   53L
   putative RNA binding site
   53L, 56F, 60N, 62S, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   56F
   putative RNA binding site
   53L, 56F, 60N, 62S, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   60N
   putative RNA binding site
   53L, 56F, 60N, 62S, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   62S
   putative RNA binding site
   53L, 56F, 60N, 62S, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   66C
   putative RNA binding site
   53L, 56F, 60N, 62S, 66C
   CDD
   cd18983 (CBD_MSL3_like)
4. DNA binding site c...
   53L
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   55H
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   56F
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   57Q
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   58G
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   59W
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   60N
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   62S
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   63W
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   64D
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   65R
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)
   66C
   DNA binding site
   53L, 55H, 56F, 57Q, 58G, 59W, 60N, 62S, 63W, 64D, 65R, 66C
   CDD
   cd18983 (CBD_MSL3_like)

### GO term prediction

#### Biological Process

GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated

#### Molecular Function

None predicted.

#### Cellular Component

GO:0005634 nucleus

Generated with InterProScan 5.45-80.0