Protein

## Lalb_11220

Length
150 amino acids

### Protein family membership

- Sterol transport protein NPC2-like (IPR039670)

### Homologous superfamilies

1. Homologous superfamily
   22 - 149
   - Immunoglobulin E-set (IPR014756)

1 20 40 60 80 100 120 140 150

### Domains and repeats

1. Domain
   22 - 147
   - MD-2-related lipid-recognition domain (IPR003172)
     - Npc2 like, ML domain (IPR033916)

1 20 40 60 80 100 120 140 150

### Detailed signature matches

1. IPR014756
   Immunoglobulin E-set
   1. SSF81296 (E set dom...)
      22 - 149
      SUPERFAMILY
      SSF81296 (E set domains)
2. IPR039670
   Sterol transport protein NPC2-like
   1. PTHR11306 (NIEMANN ...)
      3 - 149
      PANTHER
      PTHR11306 (NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED)
3. IPR003172
   MD-2-related lipid-recognition domain
   1. PF02221 (E1_DerP2_D...)
      22 - 147
      Pfam
      PF02221 (E1_DerP2_DerF2)
   2. SM00737 (pgtp_13)
      23 - 146
      SMART
      SM00737 (pgtp_13)
4. IPR033916
   Npc2 like, ML domain
   1. cd00916 (Npc2_like)
      23 - 146
      CDD
      cd00916 (Npc2_like)

no IPR
Unintegrated signatures

1. G3DSA:2.60.40...
   20 - 150
   GENE3D
   G3DSA:2.60.40.770 (G3DSA:2.60.40.770)
2. PTHR11306:SF36 (NIE...)
   3 - 149
   PANTHER
   PTHR11306:SF36 (NIEMANN-PICK TYPE C-2C-RELATED)

### Residue annotation

1. putative cholester...
   84Y
   putative cholesterol/lipid binding site
   84Y, 116V, 120Y
   CDD
   cd00916 (Npc2_like)
   116V
   putative cholesterol/lipid binding site
   84Y, 116V, 120Y
   CDD
   cd00916 (Npc2_like)
   120Y
   putative cholesterol/lipid binding site
   84Y, 116V, 120Y
   CDD
   cd00916 (Npc2_like)

### GO term prediction

#### Biological Process

GO:0032367 intracellular cholesterol transport

#### Molecular Function

None predicted.

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0