Protein

## Lalb_10735

Length
212 amino acids

### Protein family membership

- Atypical dual specificity phosphatase (IPR020417)
  - Atypical dual specificity phosphatase, subfamily A (IPR020405)

### Homologous superfamilies

1. Homologous superfamily
   44 - 211
   - Protein-tyrosine phosphatase-like (IPR029021)

1 20 40 60 80 100 120 140 160 180 200 212

### Domains and repeats

1. Domain
   60 - 208
   - Tyrosine specific protein phosphatases domain (IPR000387)
     - Dual specificity protein phosphatase domain (IPR020422)
2. Domain
   68 - 205
   - Dual specificity phosphatase, catalytic domain (IPR000340)

1 20 40 60 80 100 120 140 160 180 200 212

### Detailed signature matches

1. IPR029021
   Protein-tyrosine phosphatase-like
   1. SSF52799 ((Phosphot...)
      45 - 210
      SUPERFAMILY
      SSF52799 ((Phosphotyrosine protein) phosphatases II)
   2. G3DSA:3.90.19... (P...)
      44 - 211
      GENE3D
      G3DSA:3.90.190.10 (Protein tyrosine phosphatase superfamily)
2. IPR020417
   Atypical dual specificity phosphatase
   1. PR01908 (ADSPHPHTASE)
      132 - 143
      PRINTS
      PR01908 (ADSPHPHTASE)
      65 - 77
      PRINTS
      PR01908 (ADSPHPHTASE)
      82 - 93
      PRINTS
      PR01908 (ADSPHPHTASE)
      116 - 125
      PRINTS
      PR01908 (ADSPHPHTASE)
3. IPR020405
   Atypical dual specificity phosphatase, subfamily A
   1. PR01909 (ADSPHPHTASEA)
      62 - 73
      PRINTS
      PR01909 (ADSPHPHTASEA)
      82 - 91
      PRINTS
      PR01909 (ADSPHPHTASEA)
      136 - 145
      PRINTS
      PR01909 (ADSPHPHTASEA)
4. IPR020422
   Dual specificity protein phosphatase domain
   1. SM00195 (dsp_5)
      60 - 206
      SMART
      SM00195 (dsp_5)
   2. PS50054 (TYR_PHOSPH...)
      63 - 208
      PROSITE profiles
      PS50054 (TYR_PHOSPHATASE_DUAL)
5. IPR000340
   Dual specificity phosphatase, catalytic domain
   1. PF00782 (DSPc)
      68 - 205
      Pfam
      PF00782 (DSPc)
6. IPR000387
   Tyrosine specific protein phosphatases domain
   1. PS50056 (TYR_PHOSPH...)
      131 - 188
      PROSITE profiles
      PS50056 (TYR_PHOSPHATASE_2)
7. IPR016130
   Protein-tyrosine phosphatase, active site
   1. PS00383 (TYR_PHOSPH...)
      152 - 162
      PROSITE patterns
      PS00383 (TYR_PHOSPHATASE_1)

no IPR
Unintegrated signatures

1. PTHR45682 (FAMILY N...)
   59 - 211
   PANTHER
   PTHR45682 (FAMILY NOT NAMED)
2. cd14515 (DUSP3-like)
   61 - 207
   CDD
   cd14515 (DUSP3-like)

### Residue annotation

1. active site cd14515
   72D
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   123D
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   154C
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   155M
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   156L
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   157G
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   158M
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   159S
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   160R
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   191Q
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   192P
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   193N
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
   194D
   active site
   72D, 123D, 154C, 155M, 156L, 157G, 158M, 159S, 160R, 191Q, 192P, 193N, 194D
   CDD
   cd14515 (DUSP3-like)
2. catalytic site cd1...
   154C
   catalytic site
   154C, 160R
   CDD
   cd14515 (DUSP3-like)
   160R
   catalytic site
   154C, 160R
   CDD
   cd14515 (DUSP3-like)

### GO term prediction

#### Biological Process

GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

#### Molecular Function

GO:0004725 protein tyrosine phosphatase activity
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0016791 phosphatase activity

#### Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0