Pathway_ID Pathway_Name Accession_Count Accessions KEGG: 00010+1.8.1.4 Glycolysis / Gluconeogenesis 1 LLUN000029-PA KEGG: 00460+2.1.2.1 Cyanoamino acid metabolism 3 LLUN000209-PA;LLUN011129-PA;LLUN006558-PA MetaCyc: PWY-7219 Adenosine ribonucleotides de novo biosynthesis 5 LLUN000764-PA;LLUN006609-PA;LLUN000266-PA;LLUN002429-PA;LLUN008895-PA KEGG: 00780+4.2.1.59 Biotin metabolism 1 LLUN000176-PA Reactome: R-HSA-975871 MyD88 cascade initiated on plasma membrane 1 LLUN002907-PA MetaCyc: PWY-6737 Starch degradation V 6 LLUN000671-PA;LLUN010451-PA;LLUN004023-PA;LLUN001762-PA;LLUN000667-PA;LLUN000295-PA Reactome: R-HSA-391160 Signal regulatory protein family interactions 2 LLUN007016-PA;LLUN012391-PA MetaCyc: PWY-6607 Guanosine nucleotides degradation I 2 LLUN009431-PA;LLUN000322-PA Reactome: R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 16 LLUN002581-PA;LLUN003209-PA;LLUN003554-PA;LLUN007825-PA;LLUN003553-PA;LLUN004100-PA;LLUN011766-PA;LLUN009062-PA;LLUN000039-PA;LLUN011179-PA;LLUN006353-PA;LLUN003240-PA;LLUN008923-PA;LLUN006723-PA;LLUN002707-PA;LLUN001322-PA KEGG: 00680+3.1.3.11 Methane metabolism 2 LLUN008377-PA;LLUN000273-PA KEGG: 00270+2.5.1.47 Cysteine and methionine metabolism 1 LLUN000230-PA Reactome: R-HSA-1912420 Pre-NOTCH Processing in Golgi 1 LLUN003131-PA Reactome: R-HSA-917977 Transferrin endocytosis and recycling 13 LLUN002284-PA;LLUN005731-PA;LLUN005643-PA;LLUN005072-PA;LLUN002836-PA;LLUN004088-PA;LLUN010285-PA;LLUN002241-PA;LLUN004638-PA;LLUN012843-PA;LLUN004087-PA;LLUN012460-PA;LLUN012577-PA MetaCyc: PWY-7849 Urate conversion to allantoin III 2 LLUN012972-PA;LLUN009875-PA KEGG: 00650+1.3.5.1 Butanoate metabolism 4 LLUN008348-PA;LLUN000260-PA;LLUN012663-PA;LLUN011041-PA Reactome: R-HSA-189200 Cellular hexose transport 12 LLUN012088-PA;LLUN003810-PA;LLUN004200-PA;LLUN006534-PA;LLUN010609-PA;LLUN006802-PA;LLUN005865-PA;LLUN002563-PA;LLUN000911-PA;LLUN002458-PA;LLUN005177-PA;LLUN012420-PA Reactome: R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 2 LLUN011839-PA;LLUN008044-PA Reactome: R-HSA-418594 G alpha (i) signalling events 14 LLUN007694-PA;LLUN008739-PA;LLUN012629-PA;LLUN009773-PA;LLUN001362-PA;LLUN009560-PA;LLUN004610-PA;LLUN004430-PA;LLUN000488-PA;LLUN008293-PA;LLUN001888-PA;LLUN009028-PA;LLUN001951-PA;LLUN006187-PA MetaCyc: PWY-5083 NAD/NADH phosphorylation and dephosphorylation 1 LLUN008323-PA Reactome: R-HSA-6807004 Negative regulation of MET activity 4 LLUN012461-PA;LLUN005530-PA;LLUN000806-PA;LLUN000805-PA Reactome: R-HSA-6785470 tRNA processing in the mitochondrion 2 LLUN007103-PA;LLUN001873-PA Reactome: R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 8 LLUN012494-PA;LLUN009254-PA;LLUN005530-PA;LLUN011975-PA;LLUN000389-PA;LLUN009680-PA;LLUN003844-PA;LLUN005642-PA Reactome: R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 2 LLUN010444-PA;LLUN008644-PA MetaCyc: PWY-5939 Pyruvate fermentation to (R)-acetoin II 2 LLUN000551-PA;LLUN000044-PA Reactome: R-HSA-445144 Signal transduction by L1 2 LLUN002516-PA;LLUN008475-PA MetaCyc: PWY-6733 Sporopollenin precursors biosynthesis 9 LLUN008939-PA;LLUN012272-PA;LLUN010659-PA;LLUN007057-PA;LLUN007115-PA;LLUN011511-PA;LLUN004653-PA;LLUN002150-PA;LLUN003549-PA KEGG: 00710+4.1.1.31 Carbon fixation in photosynthetic organisms 1 LLUN000543-PA Reactome: R-HSA-1963642 PI3K events in ERBB2 signaling 1 LLUN000021-PA KEGG: 00625+1.1.1.1 Chloroalkane and chloroalkene degradation 1 LLUN012888-PA MetaCyc: PWY-7282 4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis 1 LLUN009995-PA Reactome: R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 12 LLUN012442-PA;LLUN010444-PA;LLUN001290-PA;LLUN008644-PA;LLUN011861-PA;LLUN007911-PA;LLUN000521-PA;LLUN001609-PA;LLUN005292-PA;LLUN009178-PA;LLUN009871-PA;LLUN001676-PA MetaCyc: PWY-4061 Glutathione-mediated detoxification I 5 LLUN001088-PA;LLUN008086-PA;LLUN000741-PA;LLUN000193-PA;LLUN008487-PA Reactome: R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 14 LLUN011861-PA;LLUN007911-PA;LLUN001654-PA;LLUN009747-PA;LLUN001290-PA;LLUN009178-PA;LLUN001676-PA;LLUN009871-PA;LLUN009131-PA;LLUN002218-PA;LLUN011586-PA;LLUN007798-PA;LLUN009648-PA;LLUN000521-PA MetaCyc: PWY-5740 GDP-L-colitose biosynthesis 1 LLUN000234-PA Reactome: R-HSA-5657655 MGMT-mediated DNA damage reversal 5 LLUN007481-PA;LLUN000760-PA;LLUN000300-PA;LLUN004588-PA;LLUN000897-PA KEGG: 00230+3.2.2.4 Purine metabolism 1 LLUN000166-PA Reactome: R-HSA-390450 Folding of actin by CCT/TriC 8 LLUN010206-PA;LLUN013251-PA;LLUN002905-PA;LLUN010388-PA;LLUN011652-PA;LLUN004553-PA;LLUN001889-PA;LLUN013198-PA KEGG: 00920+1.8.1.2 Sulfur metabolism 2 LLUN000318-PA;LLUN000677-PA Reactome: R-HSA-6803529 FGFR2 alternative splicing 9 LLUN000521-PA;LLUN001676-PA;LLUN009871-PA;LLUN009131-PA;LLUN009178-PA;LLUN001290-PA;LLUN007911-PA;LLUN001654-PA;LLUN011861-PA Reactome: R-HSA-5632987 Defective Mismatch Repair Associated With PMS2 1 LLUN002096-PA Reactome: R-HSA-2408508 Metabolism of ingested SeMet, Sec, MeSec into H2Se 5 LLUN012949-PA;LLUN008836-PA;LLUN000541-PA;LLUN000310-PA;LLUN000669-PA Reactome: R-HSA-381771 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 3 LLUN001397-PA;LLUN005822-PA;LLUN009969-PA MetaCyc: PWY-7778 2-methylpropene degradation 4 LLUN011561-PA;LLUN007706-PA;LLUN000586-PA;LLUN008953-PA KEGG: 00040+5.1.3.1 Pentose and glucuronate interconversions 2 LLUN010698-PA;LLUN010699-PA KEGG: 00600+3.1.3.4 Sphingolipid metabolism 1 LLUN003443-PA Reactome: R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 8 LLUN012097-PA;LLUN004076-PA;LLUN004685-PA;LLUN012273-PA;LLUN005530-PA;LLUN000845-PA;LLUN007882-PA;LLUN000848-PA Reactome: R-HSA-69052 Switching of origins to a post-replicative state 5 LLUN008160-PA;LLUN004578-PA;LLUN008154-PA;LLUN008146-PA;LLUN007051-PA Reactome: R-HSA-1236974 ER-Phagosome pathway 33 LLUN009994-PA;LLUN004861-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN008960-PA;LLUN012548-PA;LLUN005440-PA;LLUN003501-PA;LLUN010012-PA;LLUN003215-PA;LLUN004706-PA;LLUN008477-PA;LLUN005610-PA;LLUN004794-PA;LLUN000089-PA;LLUN006627-PA;LLUN009980-PA;LLUN008342-PA;LLUN001256-PA;LLUN006525-PA;LLUN005030-PA;LLUN013272-PA;LLUN003629-PA;LLUN005593-PA;LLUN004508-PA;LLUN008564-PA;LLUN005530-PA;LLUN004648-PA;LLUN002894-PA Reactome: R-HSA-427975 Proton/oligopeptide cotransporters 3 LLUN003917-PA;LLUN008428-PA;LLUN003918-PA Reactome: R-HSA-419037 NCAM1 interactions 2 LLUN000252-PA;LLUN004092-PA Reactome: R-HSA-964975 Vitamins B6 activation to pyridoxal phosphate 2 LLUN009995-PA;LLUN006056-PA Reactome: R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 9 LLUN002516-PA;LLUN004685-PA;LLUN004076-PA;LLUN012097-PA;LLUN000848-PA;LLUN007882-PA;LLUN000845-PA;LLUN005530-PA;LLUN012273-PA Reactome: R-HSA-4549349 Defective ALG2 causes ALG2-CDG (CDG-1i) 2 LLUN008157-PA;LLUN000527-PA MetaCyc: PWY-7979 Protein O-mannosylation III (mammals, core M3) 5 LLUN008266-PA;LLUN006126-PA;LLUN004509-PA;LLUN004843-PA;LLUN006904-PA KEGG: 00051+2.7.1.197 Fructose and mannose metabolism 1 LLUN001206-PA Reactome: R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 17 LLUN001776-PA;LLUN002678-PA;LLUN011775-PA;LLUN013269-PA;LLUN008894-PA;LLUN010831-PA;LLUN010933-PA;LLUN012529-PA;LLUN007180-PA;LLUN011163-PA;LLUN003438-PA;LLUN004789-PA;LLUN008374-PA;LLUN001860-PA;LLUN000604-PA;LLUN007599-PA;LLUN000563-PA KEGG: 04660+2.7.10.2 T cell receptor signaling pathway 3 LLUN012391-PA;LLUN009259-PA;LLUN007016-PA KEGG: 00623+1.1.1.35 Toluene degradation 4 LLUN011561-PA;LLUN000586-PA;LLUN008953-PA;LLUN007706-PA KEGG: 00480+1.1.1.49 Glutathione metabolism 1 LLUN009154-PA KEGG: 00471+6.3.2.8 D-Glutamine and D-glutamate metabolism 1 LLUN000040-PA KEGG: 00592+3.1.1.32+3.1.1.4 alpha-Linolenic acid metabolism 1 LLUN000563-PA Reactome: R-HSA-5358346 Hedgehog ligand biogenesis 34 LLUN003215-PA;LLUN004706-PA;LLUN010012-PA;LLUN008477-PA;LLUN005610-PA;LLUN004794-PA;LLUN011331-PA;LLUN000089-PA;LLUN004861-PA;LLUN009994-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN008960-PA;LLUN012548-PA;LLUN003501-PA;LLUN005440-PA;LLUN010850-PA;LLUN013272-PA;LLUN005030-PA;LLUN003629-PA;LLUN005593-PA;LLUN004508-PA;LLUN005656-PA;LLUN005530-PA;LLUN002894-PA;LLUN006627-PA;LLUN009980-PA;LLUN008342-PA;LLUN001628-PA;LLUN006525-PA KEGG: 00410+4.2.1.17 beta-Alanine metabolism 4 LLUN011561-PA;LLUN008953-PA;LLUN000586-PA;LLUN007706-PA Reactome: R-HSA-196836 Vitamin C (ascorbate) metabolism 4 LLUN008487-PA;LLUN000519-PA;LLUN008086-PA;LLUN000262-PA Reactome: R-HSA-71288 Creatine metabolism 2 LLUN011169-PA;LLUN009572-PA MetaCyc: PWY-7224 Purine deoxyribonucleosides salvage 5 LLUN006247-PA;LLUN000213-PA;LLUN012628-PA;LLUN011985-PA;LLUN012527-PA KEGG: 00900+1.1.1.267 Terpenoid backbone biosynthesis 1 LLUN000174-PA KEGG: 04151+2.7.11.1 PI3K-Akt signaling pathway 15 LLUN000510-PA;LLUN010447-PA;LLUN011988-PA;LLUN007666-PA;LLUN001111-PA;LLUN012849-PA;LLUN011312-PA;LLUN002957-PA;LLUN006440-PA;LLUN005145-PA;LLUN012841-PA;LLUN007496-PA;LLUN009259-PA;LLUN009503-PA;LLUN007485-PA Reactome: R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 3 LLUN008644-PA;LLUN002369-PA;LLUN010444-PA Reactome: R-HSA-5610783 Degradation of GLI2 by the proteasome 31 LLUN006525-PA;LLUN003501-PA;LLUN005440-PA;LLUN012548-PA;LLUN008960-PA;LLUN008342-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN002998-PA;LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN009994-PA;LLUN004861-PA;LLUN006627-PA;LLUN006111-PA;LLUN002894-PA;LLUN000089-PA;LLUN005530-PA;LLUN004508-PA;LLUN004794-PA;LLUN005593-PA;LLUN005610-PA;LLUN008477-PA;LLUN003629-PA;LLUN013272-PA;LLUN003215-PA;LLUN004706-PA;LLUN005030-PA;LLUN010012-PA Reactome: R-HSA-8854214 TBC/RABGAPs 1 LLUN009495-PA Reactome: R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 5 LLUN009047-PA;LLUN009048-PA;LLUN003829-PA;LLUN008793-PA;LLUN002516-PA KEGG: 00405+4.1.3.27 Phenazine biosynthesis 2 LLUN000681-PA;LLUN012019-PA KEGG: 00603+3.2.1.52 Glycosphingolipid biosynthesis - globo and isoglobo series 6 LLUN003183-PA;LLUN007651-PA;LLUN009341-PA;LLUN010383-PA;LLUN008090-PA;LLUN007975-PA KEGG: 00220+1.2.1.38 Arginine biosynthesis 1 LLUN000544-PA Reactome: R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 1 LLUN011378-PA Reactome: R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 32 LLUN009994-PA;LLUN004861-PA;LLUN010119-PA;LLUN006111-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN008960-PA;LLUN012548-PA;LLUN003501-PA;LLUN005440-PA;LLUN004706-PA;LLUN003215-PA;LLUN010012-PA;LLUN008477-PA;LLUN005610-PA;LLUN004794-PA;LLUN000089-PA;LLUN006627-PA;LLUN009980-PA;LLUN008342-PA;LLUN006525-PA;LLUN013272-PA;LLUN005030-PA;LLUN003629-PA;LLUN005593-PA;LLUN004508-PA;LLUN005530-PA;LLUN002894-PA Reactome: R-HSA-167162 RNA Polymerase II HIV Promoter Escape 26 LLUN008863-PA;LLUN008198-PA;LLUN007705-PA;LLUN001565-PA;LLUN008159-PA;LLUN007911-PA;LLUN001301-PA;LLUN012654-PA;LLUN006269-PA;LLUN004030-PA;LLUN010602-PA;LLUN009871-PA;LLUN001290-PA;LLUN008199-PA;LLUN011583-PA;LLUN005474-PA;LLUN011861-PA;LLUN002995-PA;LLUN001654-PA;LLUN008353-PA;LLUN000521-PA;LLUN009851-PA;LLUN010911-PA;LLUN009178-PA;LLUN007987-PA;LLUN001676-PA MetaCyc: PWY-6969 TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) 21 LLUN012634-PA;LLUN012438-PA;LLUN012993-PA;LLUN000143-PA;LLUN005021-PA;LLUN000260-PA;LLUN012407-PA;LLUN000276-PA;LLUN003300-PA;LLUN012663-PA;LLUN011041-PA;LLUN008348-PA;LLUN007878-PA;LLUN000255-PA;LLUN000144-PA;LLUN007879-PA;LLUN011264-PA;LLUN009867-PA;LLUN007673-PA;LLUN008350-PA;LLUN007880-PA Reactome: R-HSA-75109 Triglyceride biosynthesis 1 LLUN003443-PA Reactome: R-HSA-416476 G alpha (q) signalling events 9 LLUN008499-PA;LLUN009048-PA;LLUN009560-PA;LLUN006897-PA;LLUN003108-PA;LLUN008739-PA;LLUN009047-PA;LLUN012479-PA;LLUN005278-PA MetaCyc: PWY-6807 Xyloglucan degradation II (exoglucanase) 7 LLUN005138-PA;LLUN001229-PA;LLUN005137-PA;LLUN000904-PA;LLUN000905-PA;LLUN012652-PA;LLUN010751-PA KEGG: 00051+5.3.1.1 Fructose and mannose metabolism 2 LLUN009807-PA;LLUN000535-PA KEGG: 00240+2.1.3.2 Pyrimidine metabolism 1 LLUN000087-PA KEGG: 00030+1.1.1.49 Pentose phosphate pathway 1 LLUN009154-PA Reactome: R-HSA-8963684 Tyrosine catabolism 5 LLUN001354-PA;LLUN001355-PA;LLUN005637-PA;LLUN002365-PA;LLUN001356-PA KEGG: 00010+4.1.1.32 Glycolysis / Gluconeogenesis 1 LLUN003283-PA KEGG: 00524+2.7.1.2 Neomycin, kanamycin and gentamicin biosynthesis 1 LLUN009874-PA Reactome: R-HSA-6811555 PI5P Regulates TP53 Acetylation 2 LLUN000443-PA;LLUN000554-PA KEGG: 00010+2.7.1.2 Glycolysis / Gluconeogenesis 1 LLUN009874-PA MetaCyc: PWY-4041 Gamma-glutamyl cycle 3 LLUN001088-PA;LLUN000741-PA;LLUN000193-PA KEGG: 00220+3.5.1.54+6.3.4.6 Arginine biosynthesis 1 LLUN001217-PA Reactome: R-HSA-198323 AKT phosphorylates targets in the cytosol 1 LLUN005189-PA Reactome: R-HSA-2160916 Hyaluronan uptake and degradation 6 LLUN003183-PA;LLUN010751-PA;LLUN009341-PA;LLUN000905-PA;LLUN010383-PA;LLUN008090-PA MetaCyc: PWY-7726 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase) 7 LLUN011561-PA;LLUN011810-PA;LLUN009068-PA;LLUN000585-PA;LLUN007706-PA;LLUN008953-PA;LLUN000586-PA Reactome: R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 9 LLUN008737-PA;LLUN009996-PA;LLUN010592-PA;LLUN007391-PA;LLUN004270-PA;LLUN004269-PA;LLUN005530-PA;LLUN004464-PA;LLUN011978-PA MetaCyc: PWY-7234 Inosine-5'-phosphate biosynthesis III 4 LLUN010078-PA;LLUN008637-PA;LLUN002429-PA;LLUN004569-PA KEGG: 00051+5.4.2.8 Fructose and mannose metabolism 1 LLUN007218-PA MetaCyc: PWY-6944 Androstenedione degradation 5 LLUN011561-PA;LLUN000586-PA;LLUN008953-PA;LLUN007706-PA;LLUN000585-PA Reactome: R-HSA-6787639 GDP-fucose biosynthesis 2 LLUN001185-PA;LLUN000234-PA KEGG: 00710+2.6.1.1 Carbon fixation in photosynthetic organisms 1 LLUN009219-PA MetaCyc: PWY-6987 Lipoate biosynthesis and incorporation III (Bacillus) 2 LLUN011228-PA;LLUN008045-PA KEGG: 00997+2.3.1.30 Biosynthesis of various secondary metabolites - part 3 1 LLUN000532-PA Reactome: R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 5 LLUN009996-PA;LLUN008719-PA;LLUN008476-PA;LLUN002096-PA;LLUN007180-PA MetaCyc: PWY-5046 2-oxoisovalerate decarboxylation to isobutanoyl-CoA 1 LLUN000029-PA Reactome: R-HSA-5625970 RHO GTPases activate KTN1 2 LLUN006122-PA;LLUN002031-PA MetaCyc: PWY-7288 Fatty acid beta-oxidation VII (yeast peroxisome) 1 LLUN000585-PA MetaCyc: PWY-6948 Sitosterol degradation to androstenedione 1 LLUN000585-PA Reactome: R-HSA-70350 Fructose catabolism 4 LLUN003924-PA;LLUN000376-PA;LLUN000073-PA;LLUN001623-PA Reactome: R-HSA-425366 Transport of bile salts and organic acids, metal ions and amine compounds 3 LLUN004779-PA;LLUN011594-PA;LLUN011996-PA Reactome: R-HSA-8854518 AURKA Activation by TPX2 4 LLUN002475-PA;LLUN010357-PA;LLUN009115-PA;LLUN011046-PA MetaCyc: PWY-7663 Gondoate biosynthesis (anaerobic) 4 LLUN005169-PA;LLUN000184-PA;LLUN000176-PA;LLUN003811-PA Reactome: R-HSA-8941284 RUNX2 regulates chondrocyte maturation 3 LLUN009498-PA;LLUN009496-PA;LLUN009497-PA Reactome: R-HSA-9665247 Resistance of ERBB2 KD mutants to osimertinib 2 LLUN008205-PA;LLUN008416-PA Reactome: R-HSA-5578749 Transcriptional regulation by small RNAs 18 LLUN000521-PA;LLUN001860-PA;LLUN009178-PA;LLUN008699-PA;LLUN007599-PA;LLUN001676-PA;LLUN001290-PA;LLUN003438-PA;LLUN004789-PA;LLUN008374-PA;LLUN011861-PA;LLUN009871-PA;LLUN001776-PA;LLUN013269-PA;LLUN008894-PA;LLUN010831-PA;LLUN007911-PA;LLUN012529-PA Reactome: R-HSA-427413 NoRC negatively regulates rRNA expression 17 LLUN001565-PA;LLUN001605-PA;LLUN007911-PA;LLUN011477-PA;LLUN001301-PA;LLUN012654-PA;LLUN010602-PA;LLUN009871-PA;LLUN001290-PA;LLUN010529-PA;LLUN006959-PA;LLUN002995-PA;LLUN008353-PA;LLUN000521-PA;LLUN007122-PA;LLUN010911-PA;LLUN001676-PA MetaCyc: PWY-4381 Fatty acid biosynthesis initiation (bacteria and plants) 2 LLUN005169-PA;LLUN000178-PA MetaCyc: PWY-7426 Complex N-linked glycan biosynthesis (vertebrates) 1 LLUN007876-PA MetaCyc: PWY-6333 Acetaldehyde biosynthesis I 1 LLUN012888-PA Reactome: R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 7 LLUN009365-PA;LLUN006957-PA;LLUN001734-PA;LLUN000286-PA;LLUN001285-PA;LLUN005975-PA;LLUN004817-PA KEGG: 00450+2.7.9.3 Selenocompound metabolism 1 LLUN008878-PA Reactome: R-HSA-375165 NCAM signaling for neurite out-growth 1 LLUN002516-PA Reactome: R-HSA-73856 RNA Polymerase II Transcription Termination 16 LLUN003699-PA;LLUN011623-PA;LLUN006586-PA;LLUN009131-PA;LLUN006672-PA;LLUN002473-PA;LLUN002884-PA;LLUN006578-PA;LLUN003133-PA;LLUN003350-PA;LLUN000821-PA;LLUN000235-PA;LLUN004892-PA;LLUN012404-PA;LLUN005922-PA;LLUN003100-PA KEGG: 00720+6.2.1.1 Carbon fixation pathways in prokaryotes 2 LLUN001912-PA;LLUN000254-PA Reactome: R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 3 LLUN000235-PA;LLUN002884-PA;LLUN009131-PA KEGG: 00650+4.2.1.17+1.1.1.35 Butanoate metabolism 4 LLUN011561-PA;LLUN007706-PA;LLUN008953-PA;LLUN000586-PA KEGG: 00680+2.7.2.1 Methane metabolism 2 LLUN007189-PA;LLUN009622-PA Reactome: R-HSA-2243919 Crosslinking of collagen fibrils 2 LLUN004092-PA;LLUN001692-PA MetaCyc: PWY-622 Starch biosynthesis 7 LLUN009049-PA;LLUN009050-PA;LLUN003575-PA;LLUN002260-PA;LLUN000137-PA;LLUN006388-PA;LLUN003576-PA Reactome: R-HSA-73762 RNA Polymerase I Transcription Initiation 14 LLUN001676-PA;LLUN009871-PA;LLUN010911-PA;LLUN010602-PA;LLUN001301-PA;LLUN012654-PA;LLUN000521-PA;LLUN011477-PA;LLUN008353-PA;LLUN007911-PA;LLUN002995-PA;LLUN001565-PA;LLUN010529-PA;LLUN001290-PA MetaCyc: PWY-6282 Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) 4 LLUN003811-PA;LLUN005169-PA;LLUN000184-PA;LLUN000176-PA Reactome: R-HSA-375276 Peptide ligand-binding receptors 6 LLUN012479-PA;LLUN005278-PA;LLUN007694-PA;LLUN008293-PA;LLUN008739-PA;LLUN009560-PA MetaCyc: PWY-5972 Stearate biosynthesis I (animals) 16 LLUN005813-PA;LLUN003913-PA;LLUN008915-PA;LLUN011428-PA;LLUN001587-PA;LLUN002534-PA;LLUN001586-PA;LLUN003202-PA;LLUN001585-PA;LLUN002535-PA;LLUN003915-PA;LLUN004698-PA;LLUN004697-PA;LLUN003366-PA;LLUN000999-PA;LLUN011712-PA KEGG: 00030+2.7.1.11 Pentose phosphate pathway 3 LLUN000534-PA;LLUN002937-PA;LLUN002938-PA Reactome: R-HSA-111458 Formation of apoptosome 7 LLUN011140-PA;LLUN006174-PA;LLUN000196-PA;LLUN011888-PA;LLUN003801-PA;LLUN006836-PA;LLUN003543-PA KEGG: 00983+2.5.1.18 Drug metabolism - other enzymes 2 LLUN008487-PA;LLUN008086-PA MetaCyc: PWY-7782 Plasmalogen biosynthesis 12 LLUN004653-PA;LLUN011511-PA;LLUN007057-PA;LLUN007115-PA;LLUN003443-PA;LLUN010659-PA;LLUN012272-PA;LLUN000308-PA;LLUN008939-PA;LLUN008689-PA;LLUN003549-PA;LLUN002150-PA KEGG: 00330+3.5.1.53 Arginine and proline metabolism 1 LLUN000189-PA Reactome: R-HSA-113418 Formation of the Early Elongation Complex 21 LLUN009871-PA;LLUN002218-PA;LLUN009131-PA;LLUN009648-PA;LLUN011586-PA;LLUN012654-PA;LLUN001301-PA;LLUN010602-PA;LLUN007911-PA;LLUN001565-PA;LLUN010911-PA;LLUN009178-PA;LLUN001676-PA;LLUN008353-PA;LLUN007798-PA;LLUN000521-PA;LLUN011861-PA;LLUN009747-PA;LLUN001654-PA;LLUN002995-PA;LLUN001290-PA KEGG: 00300+6.3.2.10 Lysine biosynthesis 1 LLUN000042-PA Reactome: R-HSA-4570571 Defective RFT1 causes RFT1-CDG (CDG-1n) 1 LLUN006579-PA Reactome: R-HSA-8868766 rRNA processing in the mitochondrion 1 LLUN001873-PA MetaCyc: PWY-5981 CDP-diacylglycerol biosynthesis III 5 LLUN008689-PA;LLUN005168-PA;LLUN008432-PA;LLUN000308-PA;LLUN009855-PA KEGG: 00480+1.11.1.15 Glutathione metabolism 6 LLUN009614-PA;LLUN000412-PA;LLUN000742-PA;LLUN000547-PA;LLUN006719-PA;LLUN012501-PA Reactome: R-HSA-937039 IRAK1 recruits IKK complex 1 LLUN005530-PA Reactome: R-HSA-5627117 RHO GTPases Activate ROCKs 1 LLUN012841-PA Reactome: R-HSA-9640463 Wax biosynthesis 31 LLUN009276-PA;LLUN008938-PA;LLUN012378-PA;LLUN008149-PA;LLUN002150-PA;LLUN002151-PA;LLUN004654-PA;LLUN012754-PA;LLUN002148-PA;LLUN004653-PA;LLUN012703-PA;LLUN007115-PA;LLUN008939-PA;LLUN012272-PA;LLUN011657-PA;LLUN010780-PA;LLUN011039-PA;LLUN012071-PA;LLUN007025-PA;LLUN003549-PA;LLUN010470-PA;LLUN009427-PA;LLUN009702-PA;LLUN010659-PA;LLUN011511-PA;LLUN007057-PA;LLUN012932-PA;LLUN011941-PA;LLUN011047-PA;LLUN010916-PA;LLUN005492-PA Reactome: R-HSA-5663220 RHO GTPases Activate Formins 26 LLUN011378-PA;LLUN003554-PA;LLUN007825-PA;LLUN009963-PA;LLUN003209-PA;LLUN004221-PA;LLUN002581-PA;LLUN003438-PA;LLUN003553-PA;LLUN004100-PA;LLUN009062-PA;LLUN011766-PA;LLUN009748-PA;LLUN011179-PA;LLUN006353-PA;LLUN000039-PA;LLUN003240-PA;LLUN006122-PA;LLUN002475-PA;LLUN002707-PA;LLUN006083-PA;LLUN010831-PA;LLUN001322-PA;LLUN004095-PA;LLUN006723-PA;LLUN008923-PA KEGG: 00561+3.1.3.4 Glycerolipid metabolism 1 LLUN003443-PA KEGG: 00062+2.3.1.16 Fatty acid elongation 1 LLUN000585-PA MetaCyc: PWY-8052 2-arachidonoylglycerol biosynthesis 4 LLUN007371-PA;LLUN004409-PA;LLUN003443-PA;LLUN008499-PA KEGG: 00565+3.1.4.4 Ether lipid metabolism 1 LLUN011702-PA KEGG: 00240+3.2.2.10 Pyrimidine metabolism 1 LLUN000166-PA MetaCyc: PWY-6583 Pyruvate fermentation to butanol I 4 LLUN000586-PA;LLUN008953-PA;LLUN007706-PA;LLUN011561-PA KEGG: 00640+6.2.1.5 Propanoate metabolism 7 LLUN007880-PA;LLUN011264-PA;LLUN007879-PA;LLUN003300-PA;LLUN007878-PA;LLUN008350-PA;LLUN012993-PA MetaCyc: PWY-6133 (S)-reticuline biosynthesis II 1 LLUN000709-PA MetaCyc: PWY-7233 Ubiquinol-6 bypass biosynthesis (eukaryotic) 2 LLUN010266-PA;LLUN003684-PA MetaCyc: PWY-5537 Pyruvate fermentation to acetate V 7 LLUN012993-PA;LLUN007879-PA;LLUN011264-PA;LLUN007880-PA;LLUN008350-PA;LLUN007878-PA;LLUN003300-PA Reactome: R-HSA-5675482 Regulation of necroptotic cell death 1 LLUN005530-PA Reactome: R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 10 LLUN005530-PA;LLUN002215-PA;LLUN012461-PA;LLUN007046-PA;LLUN005475-PA;LLUN010039-PA;LLUN005188-PA;LLUN005247-PA;LLUN013036-PA;LLUN006491-PA Reactome: R-HSA-8964539 Glutamate and glutamine metabolism 11 LLUN002676-PA;LLUN000200-PA;LLUN000545-PA;LLUN002238-PA;LLUN011126-PA;LLUN000301-PA;LLUN009510-PA;LLUN012039-PA;LLUN010744-PA;LLUN000515-PA;LLUN000173-PA Reactome: R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis 5 LLUN009940-PA;LLUN002635-PA;LLUN011872-PA;LLUN004191-PA;LLUN002060-PA MetaCyc: PWY-7339 10-trans-heptadecenoyl-CoA degradation (MFE-dependent, yeast) 1 LLUN000585-PA KEGG: 00790+1.1.1.153 Folate biosynthesis 1 LLUN011786-PA KEGG: 00920+2.7.1.25 Sulfur metabolism 1 LLUN000320-PA Reactome: R-HSA-450302 activated TAK1 mediates p38 MAPK activation 1 LLUN005530-PA Reactome: R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 1 LLUN006897-PA MetaCyc: PWY-6483 Ceramide degradation (generic) 1 LLUN009763-PA Reactome: R-HSA-205043 NRIF signals cell death from the nucleus 4 LLUN007104-PA;LLUN003449-PA;LLUN001957-PA;LLUN005530-PA KEGG: 00460+2.3.2.2 Cyanoamino acid metabolism 3 LLUN001088-PA;LLUN000193-PA;LLUN000741-PA KEGG: 00750+1.2.1.72 Vitamin B6 metabolism 1 LLUN000908-PA MetaCyc: PWY-8060 2-deoxy-D-ribose degradation I 1 LLUN000065-PA MetaCyc: PWY-5973 Cis-vaccenate biosynthesis 4 LLUN000184-PA;LLUN005169-PA;LLUN000176-PA;LLUN003811-PA Reactome: R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 2 LLUN009748-PA;LLUN002516-PA Reactome: R-HSA-437239 Recycling pathway of L1 16 LLUN008923-PA;LLUN006723-PA;LLUN002707-PA;LLUN001322-PA;LLUN003240-PA;LLUN004100-PA;LLUN003553-PA;LLUN009062-PA;LLUN011766-PA;LLUN000039-PA;LLUN011179-PA;LLUN006353-PA;LLUN003209-PA;LLUN002581-PA;LLUN003554-PA;LLUN007825-PA MetaCyc: PWY-7456 Beta-(1,4)-mannan degradation 2 LLUN007218-PA;LLUN011806-PA Reactome: R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 1 LLUN005530-PA Reactome: R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 14 LLUN000521-PA;LLUN007829-PA;LLUN001167-PA;LLUN005850-PA;LLUN011849-PA;LLUN009871-PA;LLUN002544-PA;LLUN001676-PA;LLUN007985-PA;LLUN003293-PA;LLUN001290-PA;LLUN007911-PA;LLUN006359-PA;LLUN010245-PA KEGG: 00540+2.3.1.251 Lipopolysaccharide biosynthesis 2 LLUN000885-PA;LLUN000884-PA MetaCyc: PWY-8099 Tetrahydropteridine recycling 1 LLUN008319-PA Reactome: R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 12 LLUN009871-PA;LLUN001676-PA;LLUN007985-PA;LLUN000521-PA;LLUN007829-PA;LLUN001167-PA;LLUN011849-PA;LLUN005850-PA;LLUN006359-PA;LLUN007911-PA;LLUN003293-PA;LLUN001290-PA KEGG: 00380+3.5.1.9 Tryptophan metabolism 1 LLUN004035-PA Reactome: R-HSA-5654727 Negative regulation of FGFR2 signaling 2 LLUN005530-PA;LLUN002516-PA Reactome: R-HSA-1296072 Voltage gated Potassium channels 16 LLUN002618-PA;LLUN002696-PA;LLUN009301-PA;LLUN000092-PA;LLUN001393-PA;LLUN003312-PA;LLUN009709-PA;LLUN003135-PA;LLUN012883-PA;LLUN002697-PA;LLUN006465-PA;LLUN000718-PA;LLUN002129-PA;LLUN005473-PA;LLUN001336-PA;LLUN002300-PA MetaCyc: PWY-7210 Pyrimidine deoxyribonucleotides biosynthesis from CTP 13 LLUN012628-PA;LLUN011985-PA;LLUN008193-PA;LLUN006605-PA;LLUN011011-PA;LLUN000163-PA;LLUN006247-PA;LLUN003082-PA;LLUN000213-PA;LLUN001080-PA;LLUN012527-PA;LLUN010665-PA;LLUN005171-PA Reactome: R-HSA-5620922 BBSome-mediated cargo-targeting to cilium 4 LLUN005649-PA;LLUN004553-PA;LLUN001889-PA;LLUN008161-PA Reactome: R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 1 LLUN005530-PA Reactome: R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 21 LLUN001565-PA;LLUN001769-PA;LLUN007911-PA;LLUN012654-PA;LLUN002749-PA;LLUN001301-PA;LLUN010602-PA;LLUN009871-PA;LLUN011209-PA;LLUN001290-PA;LLUN006559-PA;LLUN011861-PA;LLUN002995-PA;LLUN006404-PA;LLUN008353-PA;LLUN005530-PA;LLUN004026-PA;LLUN000521-PA;LLUN010911-PA;LLUN009178-PA;LLUN001676-PA Reactome: R-HSA-4615885 SUMOylation of DNA replication proteins 15 LLUN003438-PA;LLUN001196-PA;LLUN001776-PA;LLUN004789-PA;LLUN013269-PA;LLUN000306-PA;LLUN008374-PA;LLUN000308-PA;LLUN012529-PA;LLUN008894-PA;LLUN010831-PA;LLUN011539-PA;LLUN001860-PA;LLUN007599-PA;LLUN009996-PA KEGG: 00261+4.3.3.7 Monobactam biosynthesis 1 LLUN012256-PA MetaCyc: PWY-7338 10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast) 2 LLUN000585-PA;LLUN000586-PA Reactome: R-HSA-9635644 Inhibition of membrane repair 1 LLUN012461-PA Reactome: R-HSA-77108 Utilization of Ketone Bodies 1 LLUN006982-PA Reactome: R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 31 LLUN006111-PA;LLUN009994-PA;LLUN006627-PA;LLUN004861-PA;LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN010393-PA;LLUN011115-PA;LLUN012429-PA;LLUN008342-PA;LLUN008960-PA;LLUN012548-PA;LLUN005440-PA;LLUN003501-PA;LLUN006525-PA;LLUN003215-PA;LLUN010012-PA;LLUN005030-PA;LLUN004706-PA;LLUN013272-PA;LLUN003629-PA;LLUN008477-PA;LLUN005610-PA;LLUN005593-PA;LLUN004508-PA;LLUN004794-PA;LLUN005530-PA;LLUN000089-PA;LLUN002894-PA MetaCyc: PWY-3861 Mannitol degradation II 1 LLUN011806-PA KEGG: 00052+2.7.1.2 Galactose metabolism 1 LLUN009874-PA Reactome: R-HSA-5621575 CD209 (DC-SIGN) signaling 2 LLUN008644-PA;LLUN010444-PA MetaCyc: PWY-6012-1 Acyl carrier protein activation 1 LLUN006777-PA Reactome: R-HSA-1855183 Synthesis of IP2, IP, and Ins in the cytosol 4 LLUN000211-PA;LLUN003712-PA;LLUN006316-PA;LLUN004918-PA MetaCyc: PWY-3162 L-tryptophan degradation V (side chain pathway) 1 LLUN012888-PA Reactome: R-HSA-203927 MicroRNA (miRNA) biogenesis 12 LLUN004773-PA;LLUN000521-PA;LLUN009178-PA;LLUN012699-PA;LLUN008699-PA;LLUN001676-PA;LLUN009871-PA;LLUN001290-PA;LLUN011293-PA;LLUN009676-PA;LLUN011861-PA;LLUN007911-PA Reactome: R-HSA-6782315 tRNA modification in the nucleus and cytosol 16 LLUN002297-PA;LLUN000743-PA;LLUN000264-PA;LLUN000322-PA;LLUN010826-PA;LLUN012844-PA;LLUN000303-PA;LLUN010638-PA;LLUN010586-PA;LLUN008709-PA;LLUN001335-PA;LLUN007822-PA;LLUN003882-PA;LLUN002433-PA;LLUN010311-PA;LLUN007496-PA KEGG: 00330+1.2.1.41 Arginine and proline metabolism 2 LLUN000200-PA;LLUN010744-PA KEGG: 00240+2.4.2.3 Pyrimidine metabolism 1 LLUN000578-PA KEGG: 00240+2.1.1.45 Pyrimidine metabolism 2 LLUN010665-PA;LLUN000163-PA KEGG: 00970+6.1.1.9 Aminoacyl-tRNA biosynthesis 2 LLUN000083-PA;LLUN009086-PA Reactome: R-HSA-111457 Release of apoptotic factors from the mitochondria 7 LLUN003543-PA;LLUN006836-PA;LLUN003801-PA;LLUN011888-PA;LLUN001057-PA;LLUN006174-PA;LLUN011140-PA KEGG: 00471+6.3.2.9 D-Glutamine and D-glutamate metabolism 1 LLUN000042-PA Reactome: R-HSA-5389840 Mitochondrial translation elongation 41 LLUN008500-PA;LLUN009752-PA;LLUN008596-PA;LLUN005934-PA;LLUN008289-PA;LLUN010363-PA;LLUN000285-PA;LLUN003194-PA;LLUN000171-PA;LLUN008084-PA;LLUN004962-PA;LLUN009707-PA;LLUN000277-PA;LLUN000334-PA;LLUN000172-PA;LLUN000540-PA;LLUN012172-PA;LLUN009242-PA;LLUN009134-PA;LLUN005651-PA;LLUN011356-PA;LLUN010900-PA;LLUN012749-PA;LLUN000268-PA;LLUN010361-PA;LLUN010333-PA;LLUN000269-PA;LLUN001413-PA;LLUN008324-PA;LLUN007922-PA;LLUN000336-PA;LLUN007961-PA;LLUN012315-PA;LLUN008073-PA;LLUN006358-PA;LLUN008698-PA;LLUN000761-PA;LLUN011566-PA;LLUN006713-PA;LLUN008265-PA;LLUN008128-PA KEGG: 00592+2.3.1.16 alpha-Linolenic acid metabolism 1 LLUN000585-PA KEGG: 05165+2.7.1.153 Human papillomavirus infection 1 LLUN006224-PA Reactome: R-HSA-68962 Activation of the pre-replicative complex 19 LLUN004578-PA;LLUN004644-PA;LLUN007180-PA;LLUN008154-PA;LLUN007960-PA;LLUN008160-PA;LLUN004645-PA;LLUN009292-PA;LLUN005265-PA;LLUN008476-PA;LLUN008485-PA;LLUN004948-PA;LLUN008889-PA;LLUN008083-PA;LLUN010178-PA;LLUN008245-PA;LLUN006991-PA;LLUN007051-PA;LLUN008146-PA KEGG: 00020+1.3.5.4 Citrate cycle (TCA cycle) 1 LLUN000261-PA MetaCyc: PWY-7396 Butanol and isobutanol biosynthesis (engineered) 2 LLUN000046-PA;LLUN012888-PA KEGG: 00533+2.4.1.68 Glycosaminoglycan biosynthesis - keratan sulfate 1 LLUN007876-PA MetaCyc: PWY-8055 Palmitoyl ethanolamide biosynthesis 3 LLUN000308-PA;LLUN008689-PA;LLUN003443-PA Reactome: R-HSA-2408550 Metabolism of ingested H2SeO4 and H2SeO3 into H2Se 2 LLUN000320-PA;LLUN000660-PA KEGG: 00350+1.1.1.1 Tyrosine metabolism 1 LLUN012888-PA Reactome: R-HSA-1170546 Prolactin receptor signaling 2 LLUN006111-PA;LLUN005622-PA Reactome: R-HSA-8856828 Clathrin-mediated endocytosis 12 LLUN011753-PA;LLUN011540-PA;LLUN011415-PA;LLUN003217-PA;LLUN009715-PA;LLUN012461-PA;LLUN004616-PA;LLUN010670-PA;LLUN002885-PA;LLUN006637-PA;LLUN007070-PA;LLUN005530-PA KEGG: 00480+3.4.11.23 Glutathione metabolism 1 LLUN000213-PA Reactome: R-HSA-5083628 Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 1 LLUN013133-PA KEGG: 00250+2.6.1.1 Alanine, aspartate and glutamate metabolism 1 LLUN009219-PA Reactome: R-HSA-5620924 Intraflagellar transport 7 LLUN004707-PA;LLUN008665-PA;LLUN006445-PA;LLUN001956-PA;LLUN004298-PA;LLUN004033-PA;LLUN009348-PA Reactome: R-HSA-9634635 Estrogen-stimulated signaling through PRKCZ 1 LLUN007485-PA Reactome: R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 1 LLUN002907-PA MetaCyc: PWY-7901 Glucosinolate biosynthesis from tyrosine 1 LLUN000310-PA MetaCyc: PWY-6164 3-dehydroquinate biosynthesis I 3 LLUN000339-PA;LLUN000675-PA;LLUN012864-PA MetaCyc: PWY-601 Glucosinolate biosynthesis from tryptophan 1 LLUN000310-PA KEGG: 00760+3.6.1.22 Nicotinate and nicotinamide metabolism 1 LLUN010074-PA KEGG: 00360+2.6.1.1 Phenylalanine metabolism 1 LLUN009219-PA Reactome: R-HSA-1169091 Activation of NF-kappaB in B cells 31 LLUN005530-PA;LLUN002894-PA;LLUN000089-PA;LLUN013272-PA;LLUN005030-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN003629-PA;LLUN008477-PA;LLUN005593-PA;LLUN005610-PA;LLUN004794-PA;LLUN004508-PA;LLUN008960-PA;LLUN012548-PA;LLUN003501-PA;LLUN005440-PA;LLUN006525-PA;LLUN006627-PA;LLUN009994-PA;LLUN004861-PA;LLUN006111-PA;LLUN002054-PA;LLUN009980-PA;LLUN006267-PA;LLUN002998-PA;LLUN008342-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA MetaCyc: PWY-7174 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II 5 LLUN006114-PA;LLUN000197-PA;LLUN012415-PA;LLUN011488-PA;LLUN009193-PA MetaCyc: PWY-7158 L-phenylalanine degradation V 1 LLUN008319-PA Reactome: R-HSA-432720 Lysosome Vesicle Biogenesis 3 LLUN012461-PA;LLUN011753-PA;LLUN011835-PA Reactome: R-HSA-72086 mRNA Capping 19 LLUN000521-PA;LLUN007798-PA;LLUN008353-PA;LLUN001676-PA;LLUN010911-PA;LLUN009178-PA;LLUN001290-PA;LLUN002995-PA;LLUN001654-PA;LLUN011861-PA;LLUN012654-PA;LLUN001301-PA;LLUN010602-PA;LLUN009131-PA;LLUN009871-PA;LLUN010082-PA;LLUN001565-PA;LLUN004511-PA;LLUN007911-PA KEGG: 00052+2.7.1.11 Galactose metabolism 3 LLUN002937-PA;LLUN002938-PA;LLUN000534-PA Reactome: R-HSA-2408522 Selenoamino acid metabolism 7 LLUN009127-PA;LLUN010324-PA;LLUN000150-PA;LLUN012491-PA;LLUN007278-PA;LLUN010162-PA;LLUN005993-PA KEGG: 00061+2.3.1.180 Fatty acid biosynthesis 1 LLUN005169-PA Reactome: R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 10 LLUN005975-PA;LLUN004817-PA;LLUN009365-PA;LLUN007275-PA;LLUN012190-PA;LLUN001285-PA;LLUN002498-PA;LLUN000286-PA;LLUN001734-PA;LLUN006957-PA MetaCyc: PWY-7183 Pyrimidine nucleobases salvage I 1 LLUN000773-PA Reactome: R-HSA-937041 IKK complex recruitment mediated by RIP1 1 LLUN005530-PA Reactome: R-HSA-156711 Polo-like kinase mediated events 2 LLUN001786-PA;LLUN004788-PA Reactome: R-HSA-71240 Tryptophan catabolism 2 LLUN004105-PA;LLUN003223-PA KEGG: 00030+5.3.1.9 Pentose phosphate pathway 1 LLUN000137-PA KEGG: 00750+1.1.1.262 Vitamin B6 metabolism 1 LLUN000047-PA Reactome: R-HSA-4090294 SUMOylation of intracellular receptors 3 LLUN000372-PA;LLUN012898-PA;LLUN011406-PA KEGG: 00511+3.2.1.52 Other glycan degradation 6 LLUN010383-PA;LLUN007975-PA;LLUN008090-PA;LLUN003183-PA;LLUN009341-PA;LLUN007651-PA Reactome: R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 1 LLUN005530-PA KEGG: 00220+6.3.1.2 Arginine biosynthesis 4 LLUN000514-PA;LLUN002676-PA;LLUN000515-PA;LLUN002238-PA Reactome: R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 12 LLUN007911-PA;LLUN006359-PA;LLUN001290-PA;LLUN003293-PA;LLUN007985-PA;LLUN001676-PA;LLUN009871-PA;LLUN011849-PA;LLUN005850-PA;LLUN001167-PA;LLUN000521-PA;LLUN007829-PA MetaCyc: PWY-8013 UDP-N-acetyl-D-galactosamine biosynthesis III 3 LLUN001655-PA;LLUN001189-PA;LLUN000137-PA Reactome: R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 3 LLUN004016-PA;LLUN012442-PA;LLUN005720-PA Reactome: R-HSA-1482839 Acyl chain remodelling of PE 3 LLUN003536-PA;LLUN008580-PA;LLUN001410-PA Reactome: R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 5 LLUN009996-PA;LLUN008719-PA;LLUN007180-PA;LLUN008476-PA;LLUN002096-PA KEGG: 00270+2.5.1.16 Cysteine and methionine metabolism 2 LLUN006330-PA;LLUN010439-PA MetaCyc: PWY-6142 Gluconeogenesis II (Methanobacterium thermoautotrophicum) 16 LLUN007408-PA;LLUN000535-PA;LLUN008095-PA;LLUN012863-PA;LLUN005628-PA;LLUN011949-PA;LLUN009807-PA;LLUN008096-PA;LLUN013179-PA;LLUN000832-PA;LLUN012182-PA;LLUN000137-PA;LLUN000530-PA;LLUN006407-PA;LLUN000906-PA;LLUN000543-PA MetaCyc: PWY-3561 Choline biosynthesis III 1 LLUN011702-PA Reactome: R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 9 LLUN000521-PA;LLUN009178-PA;LLUN009131-PA;LLUN009871-PA;LLUN001676-PA;LLUN001290-PA;LLUN011861-PA;LLUN001654-PA;LLUN007911-PA KEGG: 00860+4.4.1.17 Porphyrin and chlorophyll metabolism 1 LLUN003151-PA MetaCyc: PWY-6307 L-tryptophan degradation X (mammalian, via tryptamine) 1 LLUN000568-PA Reactome: R-HSA-9665246 Resistance of ERBB2 KD mutants to neratinib 2 LLUN008416-PA;LLUN008205-PA KEGG: 00520+2.6.1.16 Amino sugar and nucleotide sugar metabolism 2 LLUN001655-PA;LLUN001189-PA Reactome: R-HSA-73621 Pyrimidine catabolism 6 LLUN000064-PA;LLUN007066-PA;LLUN009904-PA;LLUN000578-PA;LLUN009750-PA;LLUN002574-PA Reactome: R-HSA-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism 2 LLUN000141-PA;LLUN000281-PA KEGG: 00400+2.7.1.71 Phenylalanine, tyrosine and tryptophan biosynthesis 1 LLUN000675-PA KEGG: 00290+4.3.1.19 Valine, leucine and isoleucine biosynthesis 1 LLUN000552-PA MetaCyc: PWY-4621 Arsenate detoxification II (glutaredoxin) 1 LLUN000774-PA Reactome: R-HSA-8963888 Chylomicron assembly 2 LLUN013210-PA;LLUN006216-PA Reactome: R-HSA-5576892 Phase 0 - rapid depolarisation 10 LLUN000252-PA;LLUN005513-PA;LLUN010550-PA;LLUN012150-PA;LLUN011839-PA;LLUN010289-PA;LLUN007877-PA;LLUN008069-PA;LLUN011545-PA;LLUN010548-PA MetaCyc: PWY-6837 Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent) 1 LLUN000586-PA KEGG: 00750+2.6.1.52 Vitamin B6 metabolism 3 LLUN011489-PA;LLUN000776-PA;LLUN012010-PA KEGG: 00500+3.2.1.4 Starch and sucrose metabolism 3 LLUN011004-PA;LLUN001402-PA;LLUN001401-PA KEGG: 00670+2.1.1.13 One carbon pool by folate 1 LLUN000141-PA Reactome: R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 37 LLUN003501-PA;LLUN005440-PA;LLUN012548-PA;LLUN008960-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN002998-PA;LLUN006267-PA;LLUN002054-PA;LLUN004861-PA;LLUN009994-PA;LLUN000089-PA;LLUN012273-PA;LLUN004076-PA;LLUN004794-PA;LLUN005610-PA;LLUN008477-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN006525-PA;LLUN007882-PA;LLUN000845-PA;LLUN008342-PA;LLUN012097-PA;LLUN004685-PA;LLUN009980-PA;LLUN006627-PA;LLUN002894-PA;LLUN000848-PA;LLUN005530-PA;LLUN004508-PA;LLUN005593-PA;LLUN003629-PA;LLUN013272-PA;LLUN005030-PA MetaCyc: PWY-6638 Sulfolactate degradation III 1 LLUN009219-PA Reactome: R-HSA-194840 Rho GTPase cycle 25 LLUN007678-PA;LLUN001551-PA;LLUN010863-PA;LLUN000943-PA;LLUN005404-PA;LLUN011044-PA;LLUN004036-PA;LLUN005469-PA;LLUN002401-PA;LLUN001506-PA;LLUN010284-PA;LLUN009283-PA;LLUN009529-PA;LLUN010554-PA;LLUN009797-PA;LLUN006410-PA;LLUN002206-PA;LLUN006122-PA;LLUN012636-PA;LLUN000242-PA;LLUN002648-PA;LLUN010410-PA;LLUN001824-PA;LLUN003356-PA;LLUN005430-PA KEGG: 00521+2.7.1.2 Streptomycin biosynthesis 1 LLUN009874-PA KEGG: 00983+1.1.1.205 Drug metabolism - other enzymes 2 LLUN000036-PA;LLUN008234-PA KEGG: 00620+2.7.1.40 Pyruvate metabolism 2 LLUN007408-PA;LLUN013179-PA MetaCyc: PWY-7411 Phosphatidate biosynthesis (yeast) 2 LLUN008689-PA;LLUN000308-PA KEGG: 04714+2.7.11.1 Thermogenesis 15 LLUN009503-PA;LLUN007485-PA;LLUN012841-PA;LLUN007496-PA;LLUN005145-PA;LLUN009259-PA;LLUN006440-PA;LLUN002957-PA;LLUN012849-PA;LLUN001111-PA;LLUN011312-PA;LLUN011988-PA;LLUN007666-PA;LLUN000510-PA;LLUN010447-PA Reactome: R-HSA-8951430 RUNX3 regulates WNT signaling 1 LLUN006125-PA KEGG: 00511+3.2.1.24 Other glycan degradation 4 LLUN003190-PA;LLUN004449-PA;LLUN010386-PA;LLUN002669-PA Reactome: R-HSA-5676934 Protein repair 4 LLUN000657-PA;LLUN011151-PA;LLUN000271-PA;LLUN006947-PA KEGG: 00710+3.1.3.11 Carbon fixation in photosynthetic organisms 2 LLUN000273-PA;LLUN008377-PA MetaCyc: PWY-3661-1 Glycine betaine degradation II (mammalian) 3 LLUN006558-PA;LLUN000209-PA;LLUN011129-PA Reactome: R-HSA-8931987 RUNX1 regulates estrogen receptor mediated transcription 3 LLUN009497-PA;LLUN009496-PA;LLUN009498-PA Reactome: R-HSA-3000171 Non-integrin membrane-ECM interactions 9 LLUN013127-PA;LLUN009875-PA;LLUN000595-PA;LLUN000590-PA;LLUN000003-PA;LLUN001511-PA;LLUN013133-PA;LLUN004092-PA;LLUN000591-PA Reactome: R-HSA-191273 Cholesterol biosynthesis 3 LLUN006160-PA;LLUN009836-PA;LLUN006161-PA KEGG: 00983+6.3.5.2 Drug metabolism - other enzymes 3 LLUN000215-PA;LLUN002619-PA;LLUN009293-PA KEGG: 00562+1.13.99.1 Inositol phosphate metabolism 1 LLUN004918-PA Reactome: R-HSA-418592 ADP signalling through P2Y purinoceptor 1 2 LLUN009047-PA;LLUN009048-PA KEGG: 00350+1.13.11.5 Tyrosine metabolism 3 LLUN001354-PA;LLUN001355-PA;LLUN001356-PA KEGG: 00240+3.5.2.3 Pyrimidine metabolism 1 LLUN004225-PA MetaCyc: PWY-7395 D-galactosamine and N-acetyl-D-galactosamine degradation 1 LLUN000895-PA Reactome: R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 21 LLUN011136-PA;LLUN005642-PA;LLUN001957-PA;LLUN011975-PA;LLUN010873-PA;LLUN002369-PA;LLUN007104-PA;LLUN003449-PA;LLUN008644-PA;LLUN006111-PA;LLUN003873-PA;LLUN010444-PA;LLUN000389-PA;LLUN009680-PA;LLUN003844-PA;LLUN011364-PA;LLUN005530-PA;LLUN010803-PA;LLUN012494-PA;LLUN009254-PA;LLUN010902-PA Reactome: R-HSA-71064 Lysine catabolism 3 LLUN009942-PA;LLUN000029-PA;LLUN008006-PA Reactome: R-HSA-611105 Respiratory electron transport 57 LLUN002417-PA;LLUN005369-PA;LLUN009607-PA;LLUN000260-PA;LLUN010453-PA;LLUN000261-PA;LLUN011105-PA;LLUN006836-PA;LLUN007190-PA;LLUN009886-PA;LLUN006174-PA;LLUN005423-PA;LLUN002997-PA;LLUN009877-PA;LLUN000892-PA;LLUN011983-PA;LLUN007194-PA;LLUN007192-PA;LLUN002639-PA;LLUN009876-PA;LLUN010662-PA;LLUN003543-PA;LLUN011597-PA;LLUN012862-PA;LLUN007360-PA;LLUN000889-PA;LLUN012130-PA;LLUN007191-PA;LLUN002659-PA;LLUN007095-PA;LLUN010033-PA;LLUN003801-PA;LLUN009753-PA;LLUN013136-PA;LLUN012663-PA;LLUN000750-PA;LLUN012509-PA;LLUN011041-PA;LLUN008387-PA;LLUN000259-PA;LLUN008348-PA;LLUN007193-PA;LLUN006807-PA;LLUN011553-PA;LLUN006149-PA;LLUN005170-PA;LLUN003349-PA;LLUN011972-PA;LLUN000751-PA;LLUN009277-PA;LLUN004701-PA;LLUN011888-PA;LLUN006540-PA;LLUN004171-PA;LLUN011140-PA;LLUN007805-PA;LLUN000160-PA Reactome: R-HSA-1538133 G0 and Early G1 2 LLUN004788-PA;LLUN001786-PA Reactome: R-HSA-4719377 Defective DPM2 causes DPM2-CDG (CDG-1u) 1 LLUN006904-PA Reactome: R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 26 LLUN001187-PA;LLUN006836-PA;LLUN005720-PA;LLUN003801-PA;LLUN011358-PA;LLUN006174-PA;LLUN000126-PA;LLUN012039-PA;LLUN008743-PA;LLUN002760-PA;LLUN004016-PA;LLUN003543-PA;LLUN012442-PA;LLUN009946-PA;LLUN011888-PA;LLUN011139-PA;LLUN011126-PA;LLUN000132-PA;LLUN010402-PA;LLUN011140-PA;LLUN008235-PA;LLUN000301-PA;LLUN000047-PA;LLUN000778-PA;LLUN001208-PA;LLUN012163-PA MetaCyc: PWY-7870 L-cysteine biosynthesis VII (from S-sulfo-L-cysteine) 1 LLUN000532-PA Reactome: R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 4 LLUN002935-PA;LLUN011160-PA;LLUN002516-PA;LLUN008668-PA Reactome: R-HSA-1482801 Acyl chain remodelling of PS 3 LLUN008580-PA;LLUN001410-PA;LLUN003536-PA Reactome: R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 11 LLUN009254-PA;LLUN012494-PA;LLUN003449-PA;LLUN007104-PA;LLUN005530-PA;LLUN000389-PA;LLUN003844-PA;LLUN011975-PA;LLUN009680-PA;LLUN001957-PA;LLUN005642-PA MetaCyc: PWY-6892 Thiazole biosynthesis I (facultative anaerobic bacteria) 4 LLUN011427-PA;LLUN000032-PA;LLUN000747-PA;LLUN000909-PA KEGG: 00051+2.7.1.3 Fructose and mannose metabolism 1 LLUN001623-PA MetaCyc: PWY-7384 Anaerobic energy metabolism (invertebrates, mitochondrial) 11 LLUN000261-PA;LLUN011264-PA;LLUN007879-PA;LLUN005021-PA;LLUN007878-PA;LLUN000255-PA;LLUN012993-PA;LLUN012634-PA;LLUN007880-PA;LLUN003300-PA;LLUN008350-PA KEGG: 00500+2.4.1.15 Starch and sucrose metabolism 1 LLUN009771-PA Reactome: R-HSA-6785631 ERBB2 Regulates Cell Motility 1 LLUN000021-PA Reactome: R-HSA-156902 Peptide chain elongation 61 LLUN004402-PA;LLUN012076-PA;LLUN006093-PA;LLUN000493-PA;LLUN004837-PA;LLUN011304-PA;LLUN007100-PA;LLUN005594-PA;LLUN002787-PA;LLUN012474-PA;LLUN001675-PA;LLUN003373-PA;LLUN006863-PA;LLUN001670-PA;LLUN007972-PA;LLUN000856-PA;LLUN012053-PA;LLUN003745-PA;LLUN003033-PA;LLUN009177-PA;LLUN009419-PA;LLUN008152-PA;LLUN001569-PA;LLUN010350-PA;LLUN008597-PA;LLUN006279-PA;LLUN003497-PA;LLUN005084-PA;LLUN003524-PA;LLUN012495-PA;LLUN003515-PA;LLUN007661-PA;LLUN011174-PA;LLUN007733-PA;LLUN010153-PA;LLUN002287-PA;LLUN006098-PA;LLUN004193-PA;LLUN010136-PA;LLUN004909-PA;LLUN005586-PA;LLUN007812-PA;LLUN012390-PA;LLUN012611-PA;LLUN002390-PA;LLUN003780-PA;LLUN007563-PA;LLUN005442-PA;LLUN000494-PA;LLUN010052-PA;LLUN000340-PA;LLUN008995-PA;LLUN006512-PA;LLUN008530-PA;LLUN002560-PA;LLUN012333-PA;LLUN009998-PA;LLUN005530-PA;LLUN010358-PA;LLUN008357-PA;LLUN009774-PA KEGG: 00562+3.1.3.25 Inositol phosphate metabolism 2 LLUN003712-PA;LLUN000211-PA KEGG: 04070+2.7.7.41 Phosphatidylinositol signaling system 1 LLUN009855-PA KEGG: 00230+3.1.3.5 Purine metabolism 1 LLUN000322-PA Reactome: R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 30 LLUN002998-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN008342-PA;LLUN009994-PA;LLUN004861-PA;LLUN006627-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA;LLUN005440-PA;LLUN003501-PA;LLUN006525-PA;LLUN008960-PA;LLUN012548-PA;LLUN005610-PA;LLUN005593-PA;LLUN004794-PA;LLUN004508-PA;LLUN005030-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN013272-PA;LLUN003629-PA;LLUN008477-PA;LLUN000089-PA;LLUN002894-PA;LLUN005530-PA KEGG: 00561+2.3.1.51 Glycerolipid metabolism 2 LLUN000308-PA;LLUN008689-PA KEGG: 00910+1.7.5.1 Nitrogen metabolism 1 LLUN011553-PA KEGG: 00380+1.11.1.6 Tryptophan metabolism 4 LLUN001796-PA;LLUN000578-PA;LLUN008395-PA;LLUN002757-PA MetaCyc: PWY-2781 Cis-zeatin biosynthesis 1 LLUN000264-PA KEGG: 00220+2.1.3.3 Arginine biosynthesis 2 LLUN000086-PA;LLUN000085-PA MetaCyc: PWY-5663 Erythro-tetrahydrobiopterin biosynthesis I 3 LLUN010032-PA;LLUN005541-PA;LLUN012034-PA Reactome: R-HSA-200425 Carnitine metabolism 3 LLUN009191-PA;LLUN005463-PA;LLUN011458-PA KEGG: 00540+2.4.99.12 Lipopolysaccharide biosynthesis 1 LLUN000527-PA KEGG: 00281+2.3.1.16 Geraniol degradation 1 LLUN000585-PA KEGG: 00680+1.1.1.284 Methane metabolism 1 LLUN012888-PA MetaCyc: PWY-3781 Aerobic respiration I (cytochrome c) 4 LLUN008348-PA;LLUN012663-PA;LLUN011041-PA;LLUN000260-PA MetaCyc: PWY-7887 Protein SAMPylation and SAMP-mediated thiolation 1 LLUN007027-PA Reactome: R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 6 LLUN011046-PA;LLUN009115-PA;LLUN012527-PA;LLUN006974-PA;LLUN007151-PA;LLUN002475-PA KEGG: 00300+4.3.3.7 Lysine biosynthesis 1 LLUN012256-PA KEGG: 00970+6.1.1.1 Aminoacyl-tRNA biosynthesis 2 LLUN012257-PA;LLUN010601-PA MetaCyc: PWY-6722 Candicidin biosynthesis 1 LLUN000178-PA MetaCyc: PWY-2261 Ascorbate glutathione cycle 2 LLUN008487-PA;LLUN008086-PA Reactome: R-HSA-3214841 PKMTs methylate histone lysines 12 LLUN005292-PA;LLUN012350-PA;LLUN011171-PA;LLUN009442-PA;LLUN008582-PA;LLUN005950-PA;LLUN010674-PA;LLUN011935-PA;LLUN003118-PA;LLUN007292-PA;LLUN011224-PA;LLUN012904-PA KEGG: 00480+4.3.2.7 Glutathione metabolism 3 LLUN000941-PA;LLUN006865-PA;LLUN005986-PA Reactome: R-HSA-72689 Formation of a pool of free 40S subunits 70 LLUN003515-PA;LLUN005084-PA;LLUN003497-PA;LLUN003524-PA;LLUN006098-PA;LLUN003033-PA;LLUN008597-PA;LLUN010350-PA;LLUN003999-PA;LLUN008152-PA;LLUN001675-PA;LLUN000856-PA;LLUN004621-PA;LLUN012053-PA;LLUN008680-PA;LLUN007972-PA;LLUN006093-PA;LLUN012076-PA;LLUN000493-PA;LLUN007100-PA;LLUN004402-PA;LLUN005594-PA;LLUN008357-PA;LLUN006512-PA;LLUN008530-PA;LLUN002560-PA;LLUN005442-PA;LLUN003780-PA;LLUN002390-PA;LLUN012611-PA;LLUN010052-PA;LLUN011199-PA;LLUN004513-PA;LLUN000494-PA;LLUN005586-PA;LLUN007812-PA;LLUN004193-PA;LLUN012390-PA;LLUN012495-PA;LLUN007733-PA;LLUN011174-PA;LLUN002287-PA;LLUN010153-PA;LLUN007661-PA;LLUN004682-PA;LLUN003745-PA;LLUN009419-PA;LLUN009177-PA;LLUN001948-PA;LLUN006279-PA;LLUN001569-PA;LLUN003373-PA;LLUN006863-PA;LLUN001670-PA;LLUN004837-PA;LLUN011304-PA;LLUN002787-PA;LLUN012474-PA;LLUN005308-PA;LLUN009998-PA;LLUN005530-PA;LLUN007425-PA;LLUN010358-PA;LLUN009774-PA;LLUN012333-PA;LLUN007563-PA;LLUN000340-PA;LLUN008995-PA;LLUN004909-PA;LLUN010136-PA MetaCyc: PWY-7036 Very long chain fatty acid biosynthesis II 18 LLUN000999-PA;LLUN011712-PA;LLUN002535-PA;LLUN003915-PA;LLUN004698-PA;LLUN003366-PA;LLUN004697-PA;LLUN008915-PA;LLUN002534-PA;LLUN011428-PA;LLUN001587-PA;LLUN001586-PA;LLUN009068-PA;LLUN003202-PA;LLUN001585-PA;LLUN011810-PA;LLUN005813-PA;LLUN003913-PA KEGG: 00520+2.7.1.1 Amino sugar and nucleotide sugar metabolism 2 LLUN005483-PA;LLUN003849-PA Reactome: R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 1 LLUN011378-PA KEGG: 00680+4.2.1.11 Methane metabolism 1 LLUN012182-PA KEGG: 00330+2.6.1.1 Arginine and proline metabolism 1 LLUN009219-PA KEGG: 00020+1.2.4.2 Citrate cycle (TCA cycle) 1 LLUN008349-PA MetaCyc: PWY-5743 3-hydroxypropanoate cycle 5 LLUN000178-PA;LLUN005628-PA;LLUN008096-PA;LLUN008095-PA;LLUN006407-PA MetaCyc: PWY-6557 Glycosaminoglycan-protein linkage region biosynthesis 1 LLUN011872-PA Reactome: R-HSA-4641265 Repression of WNT target genes 2 LLUN002616-PA;LLUN006125-PA KEGG: 00670+2.1.2.3 One carbon pool by folate 2 LLUN010078-PA;LLUN008637-PA KEGG: 00770+1.1.1.169 Pantothenate and CoA biosynthesis 1 LLUN000749-PA MetaCyc: PWY-6019 Pseudouridine degradation 2 LLUN012354-PA;LLUN006156-PA KEGG: 00071+1.1.1.1 Fatty acid degradation 1 LLUN012888-PA Reactome: R-HSA-3359469 Defective MTR causes methylmalonic aciduria and homocystinuria type cblG 2 LLUN000281-PA;LLUN000141-PA KEGG: 00220+6.3.4.5 Arginine biosynthesis 2 LLUN000151-PA;LLUN008409-PA Reactome: R-HSA-376176 Signaling by ROBO receptors 1 LLUN008470-PA KEGG: 00010+5.3.1.1 Glycolysis / Gluconeogenesis 2 LLUN009807-PA;LLUN000535-PA MetaCyc: PWY-7909 Formaldehyde oxidation VII (THF pathway) 3 LLUN000777-PA;LLUN011200-PA;LLUN010882-PA Reactome: R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 1 LLUN011378-PA KEGG: 04660+3.1.3.16 T cell receptor signaling pathway 18 LLUN009434-PA;LLUN009226-PA;LLUN006059-PA;LLUN002541-PA;LLUN000352-PA;LLUN008672-PA;LLUN007568-PA;LLUN012288-PA;LLUN002952-PA;LLUN008489-PA;LLUN005608-PA;LLUN013018-PA;LLUN004286-PA;LLUN007414-PA;LLUN010631-PA;LLUN003214-PA;LLUN002955-PA;LLUN007006-PA Reactome: R-HSA-4420097 VEGFA-VEGFR2 Pathway 7 LLUN012391-PA;LLUN012841-PA;LLUN006122-PA;LLUN008450-PA;LLUN012891-PA;LLUN007016-PA;LLUN008449-PA Reactome: R-HSA-389397 Orexin and neuropeptides FF and QRFP bind to their respective receptors 1 LLUN003108-PA KEGG: 00520+2.3.1.157+2.7.7.23 Amino sugar and nucleotide sugar metabolism 1 LLUN001188-PA MetaCyc: PWY-6289 Petrobactin biosynthesis 1 LLUN006777-PA Reactome: R-HSA-8941332 RUNX2 regulates genes involved in cell migration 3 LLUN009496-PA;LLUN009497-PA;LLUN009498-PA KEGG: 00250+6.3.1.2 Alanine, aspartate and glutamate metabolism 4 LLUN002676-PA;LLUN000514-PA;LLUN000515-PA;LLUN002238-PA Reactome: R-HSA-196108 Pregnenolone biosynthesis 1 LLUN006656-PA MetaCyc: PWY-6906 Chitin derivatives degradation 2 LLUN004963-PA;LLUN007276-PA Reactome: R-HSA-5635838 Activation of SMO 5 LLUN007710-PA;LLUN005656-PA;LLUN010850-PA;LLUN002522-PA;LLUN001628-PA Reactome: R-HSA-5620912 Anchoring of the basal body to the plasma membrane 5 LLUN003623-PA;LLUN009115-PA;LLUN006255-PA;LLUN002475-PA;LLUN011046-PA Reactome: R-HSA-2672351 Stimuli-sensing channels 23 LLUN012129-PA;LLUN001238-PA;LLUN005530-PA;LLUN010061-PA;LLUN011817-PA;LLUN012425-PA;LLUN002184-PA;LLUN005197-PA;LLUN007409-PA;LLUN000965-PA;LLUN004819-PA;LLUN002040-PA;LLUN004490-PA;LLUN003207-PA;LLUN006715-PA;LLUN012497-PA;LLUN013094-PA;LLUN012582-PA;LLUN002039-PA;LLUN006716-PA;LLUN008052-PA;LLUN005216-PA;LLUN000966-PA KEGG: 00562+2.7.1.134+2.7.1.159 Inositol phosphate metabolism 1 LLUN009162-PA Reactome: R-HSA-210455 Astrocytic Glutamate-Glutamine Uptake And Metabolism 3 LLUN002238-PA;LLUN002676-PA;LLUN000515-PA KEGG: 00515+2.4.1.109 Mannose type O-glycan biosynthesis 4 LLUN008266-PA;LLUN006126-PA;LLUN004509-PA;LLUN004843-PA Reactome: R-HSA-1679131 Trafficking and processing of endosomal TLR 2 LLUN009646-PA;LLUN004942-PA Reactome: R-HSA-2559580 Oxidative Stress Induced Senescence 6 LLUN007704-PA;LLUN004997-PA;LLUN005530-PA;LLUN002516-PA;LLUN005309-PA;LLUN005292-PA Reactome: R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 10 LLUN004789-PA;LLUN003438-PA;LLUN001776-PA;LLUN012529-PA;LLUN008894-PA;LLUN010831-PA;LLUN008374-PA;LLUN013269-PA;LLUN001860-PA;LLUN007599-PA Reactome: R-HSA-6784531 tRNA processing in the nucleus 24 LLUN008553-PA;LLUN008699-PA;LLUN007599-PA;LLUN004892-PA;LLUN001860-PA;LLUN010584-PA;LLUN008374-PA;LLUN006946-PA;LLUN005532-PA;LLUN003124-PA;LLUN003438-PA;LLUN004789-PA;LLUN000972-PA;LLUN010101-PA;LLUN013269-PA;LLUN007103-PA;LLUN012529-PA;LLUN008894-PA;LLUN010831-PA;LLUN002000-PA;LLUN000178-PA;LLUN010906-PA;LLUN001776-PA;LLUN012630-PA MetaCyc: PWY-7601 Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes) 18 LLUN009068-PA;LLUN001586-PA;LLUN003202-PA;LLUN001585-PA;LLUN008915-PA;LLUN002534-PA;LLUN011428-PA;LLUN001587-PA;LLUN003913-PA;LLUN011810-PA;LLUN005813-PA;LLUN000999-PA;LLUN011712-PA;LLUN003915-PA;LLUN004698-PA;LLUN004697-PA;LLUN003366-PA;LLUN002535-PA MetaCyc: PWY-6689 Trna splicing I 3 LLUN010101-PA;LLUN010906-PA;LLUN000972-PA Reactome: R-HSA-6807505 RNA polymerase II transcribes snRNA genes 24 LLUN007798-PA;LLUN009851-PA;LLUN009179-PA;LLUN006318-PA;LLUN000521-PA;LLUN009178-PA;LLUN009490-PA;LLUN011459-PA;LLUN001676-PA;LLUN001290-PA;LLUN011583-PA;LLUN011861-PA;LLUN012061-PA;LLUN001654-PA;LLUN005149-PA;LLUN009648-PA;LLUN006269-PA;LLUN003781-PA;LLUN005693-PA;LLUN012648-PA;LLUN009871-PA;LLUN009131-PA;LLUN010245-PA;LLUN007911-PA Reactome: R-HSA-4608870 Asymmetric localization of PCP proteins 30 LLUN005440-PA;LLUN003501-PA;LLUN006525-PA;LLUN008960-PA;LLUN012548-PA;LLUN002998-PA;LLUN010393-PA;LLUN011115-PA;LLUN012429-PA;LLUN008342-PA;LLUN004861-PA;LLUN009994-PA;LLUN006627-PA;LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN000089-PA;LLUN002894-PA;LLUN005530-PA;LLUN005610-PA;LLUN005593-PA;LLUN004794-PA;LLUN004508-PA;LLUN003215-PA;LLUN005030-PA;LLUN010012-PA;LLUN004706-PA;LLUN013272-PA;LLUN003629-PA;LLUN008477-PA MetaCyc: PWY-882 L-ascorbate biosynthesis I (L-galactose pathway) 3 LLUN007218-PA;LLUN011806-PA;LLUN000917-PA Reactome: R-HSA-69183 Processive synthesis on the lagging strand 5 LLUN010178-PA;LLUN008719-PA;LLUN009996-PA;LLUN004948-PA;LLUN006991-PA KEGG: 00790+4.2.3.12 Folate biosynthesis 1 LLUN010032-PA KEGG: 00620+2.3.1.12 Pyruvate metabolism 1 LLUN000030-PA KEGG: 00510+2.4.1.83 N-Glycan biosynthesis 1 LLUN006904-PA MetaCyc: PWY-5480 Pyruvate fermentation to ethanol I 1 LLUN012888-PA Reactome: R-HSA-1489509 DAG and IP3 signaling 1 LLUN004972-PA MetaCyc: PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline) 8 LLUN000544-PA;LLUN000546-PA;LLUN009630-PA;LLUN000151-PA;LLUN008409-PA;LLUN000049-PA;LLUN000545-PA;LLUN002360-PA Reactome: R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 9 LLUN008476-PA;LLUN011570-PA;LLUN007180-PA;LLUN005530-PA;LLUN009996-PA;LLUN005061-PA;LLUN001634-PA;LLUN008719-PA;LLUN012973-PA Reactome: R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 21 LLUN011975-PA;LLUN001957-PA;LLUN011136-PA;LLUN005642-PA;LLUN002369-PA;LLUN010873-PA;LLUN007104-PA;LLUN003449-PA;LLUN008644-PA;LLUN006111-PA;LLUN010444-PA;LLUN003873-PA;LLUN000389-PA;LLUN009680-PA;LLUN003844-PA;LLUN005530-PA;LLUN011364-PA;LLUN010803-PA;LLUN012494-PA;LLUN010902-PA;LLUN009254-PA Reactome: R-HSA-163615 PKA activation 2 LLUN004430-PA;LLUN004610-PA KEGG: 00010+6.2.1.1 Glycolysis / Gluconeogenesis 2 LLUN001912-PA;LLUN000254-PA Reactome: R-HSA-77289 Mitochondrial Fatty Acid Beta-Oxidation 3 LLUN010662-PA;LLUN000359-PA;LLUN005170-PA Reactome: R-HSA-4043916 Defective MPI causes MPI-CDG (CDG-1b) 1 LLUN011806-PA Reactome: R-HSA-400253 Circadian Clock 11 LLUN005530-PA;LLUN006648-PA;LLUN009493-PA;LLUN006801-PA;LLUN010444-PA;LLUN005720-PA;LLUN001577-PA;LLUN012442-PA;LLUN004016-PA;LLUN008644-PA;LLUN006111-PA Reactome: R-HSA-8963889 Assembly of active LPL and LIPC lipase complexes 1 LLUN008164-PA MetaCyc: PWY-7382 Lipoate biosynthesis and incorporation IV (yeast) 2 LLUN008045-PA;LLUN011228-PA MetaCyc: PWY-5386 Methylglyoxal degradation I 3 LLUN012656-PA;LLUN000969-PA;LLUN009255-PA KEGG: 00640+1.8.1.4 Propanoate metabolism 1 LLUN000029-PA Reactome: R-HSA-173599 Formation of the active cofactor, UDP-glucuronate 3 LLUN006219-PA;LLUN009234-PA;LLUN012184-PA KEGG: 00400+4.2.3.4 Phenylalanine, tyrosine and tryptophan biosynthesis 1 LLUN000675-PA Reactome: R-HSA-977443 GABA receptor activation 2 LLUN003650-PA;LLUN000415-PA Reactome: R-HSA-6811438 Intra-Golgi traffic 7 LLUN003728-PA;LLUN009459-PA;LLUN011584-PA;LLUN003718-PA;LLUN003429-PA;LLUN010728-PA;LLUN006756-PA MetaCyc: PWY-5659 GDP-mannose biosynthesis 4 LLUN011806-PA;LLUN007218-PA;LLUN000917-PA;LLUN000137-PA MetaCyc: PWY-7119 Ceramide and sphingolipid recycling and degradation (yeast) 1 LLUN009763-PA KEGG: 00230+2.7.1.20 Purine metabolism 1 LLUN009730-PA KEGG: 04150+2.7.11.1 mTOR signaling pathway 15 LLUN011988-PA;LLUN007666-PA;LLUN000510-PA;LLUN010447-PA;LLUN012841-PA;LLUN007496-PA;LLUN005145-PA;LLUN009259-PA;LLUN009503-PA;LLUN007485-PA;LLUN012849-PA;LLUN001111-PA;LLUN011312-PA;LLUN002957-PA;LLUN006440-PA Reactome: R-HSA-418886 Netrin mediated repulsion signals 2 LLUN012743-PA;LLUN003834-PA KEGG: 00680+6.2.1.1 Methane metabolism 2 LLUN000254-PA;LLUN001912-PA Reactome: R-HSA-8983711 OAS antiviral response 1 LLUN008416-PA MetaCyc: PWY-6549 L-glutamine biosynthesis III 6 LLUN002238-PA;LLUN000543-PA;LLUN012407-PA;LLUN002676-PA;LLUN000514-PA;LLUN000515-PA Reactome: R-HSA-8949215 Mitochondrial calcium ion transport 2 LLUN009652-PA;LLUN006442-PA KEGG: 00600+3.2.1.23 Sphingolipid metabolism 4 LLUN000905-PA;LLUN010751-PA;LLUN000904-PA;LLUN001229-PA MetaCyc: PWY-6168 Flavin biosynthesis III (fungi) 1 LLUN000051-PA Reactome: R-HSA-165054 Rev-mediated nuclear export of HIV RNA 12 LLUN007599-PA;LLUN008699-PA;LLUN001860-PA;LLUN012529-PA;LLUN008894-PA;LLUN010831-PA;LLUN013269-PA;LLUN008374-PA;LLUN004789-PA;LLUN003438-PA;LLUN009748-PA;LLUN001776-PA Reactome: R-HSA-5083629 Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 3 LLUN013133-PA;LLUN004509-PA;LLUN008266-PA Reactome: R-HSA-975577 N-Glycan antennae elongation 4 LLUN008394-PA;LLUN007516-PA;LLUN006661-PA;LLUN013083-PA KEGG: 00760+3.6.1.9 Nicotinate and nicotinamide metabolism 3 LLUN000110-PA;LLUN003890-PA;LLUN006214-PA Reactome: R-HSA-2022928 HS-GAG biosynthesis 5 LLUN004191-PA;LLUN008728-PA;LLUN002060-PA;LLUN012994-PA;LLUN001417-PA KEGG: 00270+5.3.1.23 Cysteine and methionine metabolism 5 LLUN009193-PA;LLUN012415-PA;LLUN011488-PA;LLUN000197-PA;LLUN006114-PA Reactome: R-HSA-110329 Cleavage of the damaged pyrimidine 4 LLUN002678-PA;LLUN000890-PA;LLUN000526-PA;LLUN005053-PA Reactome: R-HSA-445355 Smooth Muscle Contraction 6 LLUN003596-PA;LLUN001108-PA;LLUN003597-PA;LLUN005887-PA;LLUN003740-PA;LLUN011907-PA KEGG: 00513+2.4.1.68 Various types of N-glycan biosynthesis 1 LLUN007876-PA KEGG: 00720+1.1.1.37 Carbon fixation pathways in prokaryotes 3 LLUN009867-PA;LLUN000276-PA;LLUN012438-PA MetaCyc: PWY-6679 Jadomycin biosynthesis 2 LLUN005463-PA;LLUN011458-PA Reactome: R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 10 LLUN001776-PA;LLUN003438-PA;LLUN004789-PA;LLUN013269-PA;LLUN008374-PA;LLUN010831-PA;LLUN008894-PA;LLUN012529-PA;LLUN001860-PA;LLUN007599-PA Reactome: R-HSA-3371568 Attenuation phase 2 LLUN008644-PA;LLUN010444-PA MetaCyc: PWY-6435 4-hydroxybenzoate biosynthesis III (plants) 5 LLUN011561-PA;LLUN000586-PA;LLUN008953-PA;LLUN007706-PA;LLUN000585-PA Reactome: R-HSA-110312 Translesion synthesis by REV1 7 LLUN008476-PA;LLUN011570-PA;LLUN007180-PA;LLUN005530-PA;LLUN001634-PA;LLUN012973-PA;LLUN009996-PA Reactome: R-HSA-68689 CDC6 association with the ORC:origin complex 4 LLUN007960-PA;LLUN004645-PA;LLUN008245-PA;LLUN004644-PA Reactome: R-HSA-1989781 PPARA activates gene expression 34 LLUN012442-PA;LLUN006050-PA;LLUN002498-PA;LLUN001235-PA;LLUN011675-PA;LLUN004016-PA;LLUN001639-PA;LLUN006161-PA;LLUN007815-PA;LLUN008795-PA;LLUN003325-PA;LLUN010444-PA;LLUN005720-PA;LLUN008644-PA;LLUN000459-PA;LLUN009443-PA;LLUN002109-PA;LLUN013016-PA;LLUN006049-PA;LLUN009946-PA;LLUN001234-PA;LLUN007787-PA;LLUN006665-PA;LLUN002027-PA;LLUN004207-PA;LLUN004803-PA;LLUN012190-PA;LLUN008841-PA;LLUN008616-PA;LLUN011358-PA;LLUN010569-PA;LLUN012918-PA;LLUN000492-PA;LLUN006160-PA Reactome: R-HSA-674695 RNA Polymerase II Pre-transcription Events 42 LLUN001565-PA;LLUN008863-PA;LLUN008159-PA;LLUN001301-PA;LLUN002218-PA;LLUN009871-PA;LLUN009131-PA;LLUN003321-PA;LLUN008199-PA;LLUN011978-PA;LLUN001290-PA;LLUN005747-PA;LLUN009747-PA;LLUN002995-PA;LLUN009851-PA;LLUN008353-PA;LLUN007798-PA;LLUN010911-PA;LLUN009178-PA;LLUN008198-PA;LLUN011260-PA;LLUN007705-PA;LLUN007911-PA;LLUN006269-PA;LLUN012654-PA;LLUN004030-PA;LLUN010602-PA;LLUN009648-PA;LLUN011586-PA;LLUN008120-PA;LLUN004270-PA;LLUN011583-PA;LLUN001654-PA;LLUN005474-PA;LLUN011861-PA;LLUN002265-PA;LLUN000521-PA;LLUN004269-PA;LLUN007987-PA;LLUN008737-PA;LLUN012633-PA;LLUN001676-PA KEGG: 00260+4.3.1.19 Glycine, serine and threonine metabolism 1 LLUN000552-PA Reactome: R-HSA-204174 Regulation of pyruvate dehydrogenase (PDH) complex 5 LLUN000314-PA;LLUN009870-PA;LLUN000533-PA;LLUN000092-PA;LLUN000029-PA Reactome: R-HSA-111957 Cam-PDE 1 activation 1 LLUN006221-PA Reactome: R-HSA-110331 Cleavage of the damaged purine 2 LLUN000526-PA;LLUN005053-PA KEGG: 00270+2.6.1.52 Cysteine and methionine metabolism 3 LLUN011489-PA;LLUN000776-PA;LLUN012010-PA Reactome: R-HSA-8851805 MET activates RAS signaling 1 LLUN009026-PA KEGG: 00770+3.6.1.9 Pantothenate and CoA biosynthesis 3 LLUN003890-PA;LLUN006214-PA;LLUN000110-PA Reactome: R-HSA-5696395 Formation of Incision Complex in GG-NER 14 LLUN002995-PA;LLUN002277-PA;LLUN001565-PA;LLUN011775-PA;LLUN010911-PA;LLUN002231-PA;LLUN010602-PA;LLUN001301-PA;LLUN012654-PA;LLUN005995-PA;LLUN007180-PA;LLUN005530-PA;LLUN008476-PA;LLUN008353-PA MetaCyc: PWY-6123 Inosine-5'-phosphate biosynthesis I 4 LLUN010078-PA;LLUN002429-PA;LLUN004569-PA;LLUN008637-PA MetaCyc: PWY-922 Mevalonate pathway I 4 LLUN006161-PA;LLUN007815-PA;LLUN006160-PA;LLUN009836-PA Reactome: R-HSA-390648 Muscarinic acetylcholine receptors 2 LLUN003195-PA;LLUN003231-PA Reactome: R-HSA-8941858 Regulation of RUNX3 expression and activity 31 LLUN005530-PA;LLUN000089-PA;LLUN002894-PA;LLUN010012-PA;LLUN003215-PA;LLUN005030-PA;LLUN004706-PA;LLUN013272-PA;LLUN003629-PA;LLUN008477-PA;LLUN005610-PA;LLUN009498-PA;LLUN005593-PA;LLUN009496-PA;LLUN004508-PA;LLUN004794-PA;LLUN008960-PA;LLUN005440-PA;LLUN003501-PA;LLUN006525-PA;LLUN009994-PA;LLUN006627-PA;LLUN004861-PA;LLUN002054-PA;LLUN009980-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN009497-PA;LLUN012429-PA;LLUN008342-PA KEGG: 00250+4.3.1.1 Alanine, aspartate and glutamate metabolism 1 LLUN000255-PA KEGG: 00564+3.1.3.4 Glycerophospholipid metabolism 1 LLUN003443-PA MetaCyc: PWY-7286 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis 3 LLUN000335-PA;LLUN001126-PA;LLUN011248-PA Reactome: R-HSA-1483148 Synthesis of PG 3 LLUN012166-PA;LLUN011702-PA;LLUN010353-PA KEGG: 04070+3.1.3.36 Phosphatidylinositol signaling system 1 LLUN011415-PA Reactome: R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 26 LLUN012654-PA;LLUN001301-PA;LLUN006269-PA;LLUN010602-PA;LLUN004030-PA;LLUN009871-PA;LLUN008863-PA;LLUN008198-PA;LLUN001565-PA;LLUN007705-PA;LLUN008159-PA;LLUN007911-PA;LLUN008353-PA;LLUN000521-PA;LLUN009851-PA;LLUN010911-PA;LLUN009178-PA;LLUN007987-PA;LLUN001676-PA;LLUN001290-PA;LLUN011583-PA;LLUN008199-PA;LLUN005474-PA;LLUN011861-PA;LLUN002995-PA;LLUN001654-PA KEGG: 00450+4.4.1.13 Selenocompound metabolism 1 LLUN000310-PA Reactome: R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 2 LLUN005530-PA;LLUN004172-PA Reactome: R-HSA-114608 Platelet degranulation 3 LLUN002921-PA;LLUN002922-PA;LLUN007166-PA MetaCyc: PWY-6894 Thiamine diphosphate biosynthesis I (E. coli) 1 LLUN000288-PA Reactome: R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 20 LLUN000495-PA;LLUN011458-PA;LLUN005276-PA;LLUN003046-PA;LLUN012922-PA;LLUN005277-PA;LLUN005720-PA;LLUN009836-PA;LLUN009868-PA;LLUN006160-PA;LLUN009575-PA;LLUN005463-PA;LLUN009379-PA;LLUN005809-PA;LLUN002498-PA;LLUN004016-PA;LLUN012442-PA;LLUN012190-PA;LLUN000497-PA;LLUN006161-PA KEGG: 00920+2.5.1.47 Sulfur metabolism 1 LLUN000230-PA Reactome: R-HSA-6799198 Complex I biogenesis 32 LLUN007095-PA;LLUN007191-PA;LLUN007078-PA;LLUN012297-PA;LLUN007193-PA;LLUN012509-PA;LLUN009753-PA;LLUN005170-PA;LLUN011553-PA;LLUN006807-PA;LLUN006540-PA;LLUN000160-PA;LLUN007805-PA;LLUN004701-PA;LLUN009277-PA;LLUN003349-PA;LLUN012040-PA;LLUN010453-PA;LLUN005369-PA;LLUN009607-PA;LLUN010246-PA;LLUN005423-PA;LLUN009877-PA;LLUN007190-PA;LLUN012490-PA;LLUN009876-PA;LLUN010662-PA;LLUN007192-PA;LLUN007194-PA;LLUN002907-PA;LLUN007360-PA;LLUN011597-PA Reactome: R-HSA-2024101 CS/DS degradation 4 LLUN008090-PA;LLUN010383-PA;LLUN009341-PA;LLUN003183-PA KEGG: 00230+3.6.1.15 Purine metabolism 1 LLUN003082-PA KEGG: 00250+4.3.2.1 Alanine, aspartate and glutamate metabolism 2 LLUN000546-PA;LLUN002360-PA MetaCyc: PWY-6617 Adenosine nucleotides degradation III 1 LLUN000166-PA KEGG: 00680+4.1.2.13 Methane metabolism 3 LLUN000832-PA;LLUN000906-PA;LLUN011949-PA KEGG: 00740+2.7.7.2 Riboflavin metabolism 1 LLUN000051-PA Reactome: R-HSA-8863795 Downregulation of ERBB2 signaling 5 LLUN008416-PA;LLUN008205-PA;LLUN006158-PA;LLUN005530-PA;LLUN000021-PA MetaCyc: PWY-6619 Adenine and adenosine salvage VI 1 LLUN009730-PA Reactome: R-HSA-195399 VEGF binds to VEGFR leading to receptor dimerization 1 LLUN007166-PA Reactome: R-HSA-399997 Acetylcholine regulates insulin secretion 2 LLUN009047-PA;LLUN009048-PA MetaCyc: PWY-3181 L-tryptophan degradation VI (via tryptamine) 1 LLUN000568-PA Reactome: R-HSA-8934903 Receptor Mediated Mitophagy 3 LLUN011856-PA;LLUN008475-PA;LLUN001578-PA Reactome: R-HSA-8869496 TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation 4 LLUN000257-PA;LLUN011064-PA;LLUN004542-PA;LLUN009405-PA Reactome: R-HSA-167161 HIV Transcription Initiation 26 LLUN001676-PA;LLUN007987-PA;LLUN009178-PA;LLUN010911-PA;LLUN009851-PA;LLUN000521-PA;LLUN008353-PA;LLUN001654-PA;LLUN002995-PA;LLUN011861-PA;LLUN005474-PA;LLUN008199-PA;LLUN011583-PA;LLUN001290-PA;LLUN009871-PA;LLUN010602-PA;LLUN004030-PA;LLUN006269-PA;LLUN012654-PA;LLUN001301-PA;LLUN007911-PA;LLUN008159-PA;LLUN007705-PA;LLUN001565-PA;LLUN008198-PA;LLUN008863-PA MetaCyc: PWY-7977 L-methionine biosynthesis IV (archaea) 1 LLUN000141-PA KEGG: 04070+2.7.4.24+2.7.4.21 Phosphatidylinositol signaling system 1 LLUN006346-PA MetaCyc: PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I 4 LLUN000772-PA;LLUN010077-PA;LLUN006933-PA;LLUN006932-PA MetaCyc: PWY-7204 Pyridoxal 5'-phosphate salvage II (plants) 1 LLUN009995-PA MetaCyc: PWY-7589 Palmitoleate biosynthesis III (cyanobacteria) 2 LLUN008689-PA;LLUN000308-PA Reactome: R-HSA-264642 Acetylcholine Neurotransmitter Release Cycle 1 LLUN011055-PA KEGG: 00052+2.7.1.6 Galactose metabolism 2 LLUN003916-PA;LLUN004037-PA KEGG: 00710+2.7.1.14 Carbon fixation in photosynthetic organisms 1 LLUN010144-PA KEGG: 00630+4.1.3.1 Glyoxylate and dicarboxylate metabolism 1 LLUN000143-PA MetaCyc: PWY-7385 1,3-propanediol biosynthesis (engineered) 8 LLUN011949-PA;LLUN000906-PA;LLUN000534-PA;LLUN009874-PA;LLUN000137-PA;LLUN002937-PA;LLUN000832-PA;LLUN002938-PA KEGG: 00650+1.1.1.304 Butanoate metabolism 1 LLUN008647-PA Reactome: R-HSA-8850843 Phosphate bond hydrolysis by NTPDase proteins 1 LLUN011960-PA MetaCyc: PWY-7857 Adlupulone and adhumulone biosynthesis 2 LLUN000254-PA;LLUN001912-PA KEGG: 00250+1.4.3.16 Alanine, aspartate and glutamate metabolism 1 LLUN000889-PA MetaCyc: PWY-6708 Ubiquinol-8 biosynthesis (prokaryotic) 4 LLUN003684-PA;LLUN000136-PA;LLUN010266-PA;LLUN000584-PA KEGG: 00550+6.3.2.4 Peptidoglycan biosynthesis 1 LLUN000040-PA KEGG: 00270+2.1.1.14 Cysteine and methionine metabolism 2 LLUN004715-PA;LLUN000578-PA Reactome: R-HSA-8951664 Neddylation 57 LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN002998-PA;LLUN002054-PA;LLUN008272-PA;LLUN006267-PA;LLUN006111-PA;LLUN005827-PA;LLUN009994-PA;LLUN010119-PA;LLUN004861-PA;LLUN012135-PA;LLUN012351-PA;LLUN005440-PA;LLUN003501-PA;LLUN012548-PA;LLUN008960-PA;LLUN009518-PA;LLUN004794-PA;LLUN005610-PA;LLUN006404-PA;LLUN008477-PA;LLUN012562-PA;LLUN010012-PA;LLUN003215-PA;LLUN004706-PA;LLUN004489-PA;LLUN005224-PA;LLUN006784-PA;LLUN000089-PA;LLUN010723-PA;LLUN005225-PA;LLUN007862-PA;LLUN012273-PA;LLUN005907-PA;LLUN006902-PA;LLUN008342-PA;LLUN001769-PA;LLUN007187-PA;LLUN012373-PA;LLUN009980-PA;LLUN006814-PA;LLUN006627-PA;LLUN006525-PA;LLUN004382-PA;LLUN004259-PA;LLUN004508-PA;LLUN002655-PA;LLUN005593-PA;LLUN003629-PA;LLUN005030-PA;LLUN013272-PA;LLUN002894-PA;LLUN013201-PA;LLUN005530-PA;LLUN003117-PA Reactome: R-HSA-9010553 Regulation of expression of SLITs and ROBOs 95 LLUN010350-PA;LLUN008152-PA;LLUN005610-PA;LLUN008597-PA;LLUN004706-PA;LLUN003215-PA;LLUN003033-PA;LLUN010012-PA;LLUN000089-PA;LLUN006098-PA;LLUN003497-PA;LLUN005084-PA;LLUN003524-PA;LLUN003515-PA;LLUN002998-PA;LLUN005594-PA;LLUN012429-PA;LLUN009994-PA;LLUN004402-PA;LLUN006267-PA;LLUN006093-PA;LLUN012076-PA;LLUN000493-PA;LLUN002054-PA;LLUN007100-PA;LLUN003501-PA;LLUN007972-PA;LLUN000856-PA;LLUN012053-PA;LLUN001675-PA;LLUN006672-PA;LLUN002560-PA;LLUN013272-PA;LLUN008530-PA;LLUN006512-PA;LLUN008357-PA;LLUN002894-PA;LLUN012390-PA;LLUN004193-PA;LLUN006627-PA;LLUN009980-PA;LLUN005586-PA;LLUN007812-PA;LLUN000494-PA;LLUN010052-PA;LLUN006525-PA;LLUN012611-PA;LLUN002390-PA;LLUN003780-PA;LLUN005442-PA;LLUN001569-PA;LLUN006279-PA;LLUN004794-PA;LLUN003745-PA;LLUN009177-PA;LLUN006179-PA;LLUN009419-PA;LLUN008477-PA;LLUN007661-PA;LLUN011174-PA;LLUN007733-PA;LLUN002287-PA;LLUN010153-PA;LLUN012495-PA;LLUN010393-PA;LLUN011115-PA;LLUN002787-PA;LLUN012474-PA;LLUN004861-PA;LLUN004837-PA;LLUN011304-PA;LLUN009131-PA;LLUN005440-PA;LLUN001670-PA;LLUN008960-PA;LLUN003373-PA;LLUN012548-PA;LLUN006863-PA;LLUN012333-PA;LLUN005593-PA;LLUN013133-PA;LLUN004508-PA;LLUN005030-PA;LLUN003629-PA;LLUN010358-PA;LLUN009774-PA;LLUN009998-PA;LLUN004262-PA;LLUN005530-PA;LLUN008342-PA;LLUN010136-PA;LLUN004909-PA;LLUN000340-PA;LLUN008995-PA;LLUN007563-PA Reactome: R-HSA-4085001 Sialic acid metabolism 9 LLUN006288-PA;LLUN007541-PA;LLUN006286-PA;LLUN005178-PA;LLUN004540-PA;LLUN006287-PA;LLUN012575-PA;LLUN007276-PA;LLUN013139-PA Reactome: R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 3 LLUN001786-PA;LLUN009996-PA;LLUN004788-PA KEGG: 00760+3.1.3.5 Nicotinate and nicotinamide metabolism 1 LLUN000322-PA KEGG: 00230+2.7.4.3 Purine metabolism 3 LLUN006609-PA;LLUN000764-PA;LLUN008895-PA KEGG: 00010+5.4.2.12 Glycolysis / Gluconeogenesis 1 LLUN000530-PA Reactome: R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 1 LLUN011753-PA MetaCyc: PWY-7220 Adenosine deoxyribonucleotides de novo biosynthesis II 7 LLUN006247-PA;LLUN011985-PA;LLUN012628-PA;LLUN008193-PA;LLUN000213-PA;LLUN012527-PA;LLUN001080-PA MetaCyc: PWY-7013 (S)-propane-1,2-diol degradation 1 LLUN012888-PA KEGG: 00670+1.5.1.20 One carbon pool by folate 1 LLUN000542-PA MetaCyc: PWY-3661 Glycine betaine degradation I 3 LLUN006558-PA;LLUN000209-PA;LLUN011129-PA Reactome: R-HSA-1296052 Ca2+ activated K+ channels 2 LLUN001308-PA;LLUN005125-PA Reactome: R-HSA-182218 Nef Mediated CD8 Down-regulation 1 LLUN004638-PA Reactome: R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 7 LLUN004685-PA;LLUN000848-PA;LLUN012097-PA;LLUN007882-PA;LLUN004076-PA;LLUN000845-PA;LLUN012273-PA Reactome: R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 3 LLUN011046-PA;LLUN002475-PA;LLUN009115-PA KEGG: 04658+3.1.3.16 Th1 and Th2 cell differentiation 18 LLUN002955-PA;LLUN007006-PA;LLUN013018-PA;LLUN004286-PA;LLUN007414-PA;LLUN010631-PA;LLUN003214-PA;LLUN008489-PA;LLUN002952-PA;LLUN005608-PA;LLUN007568-PA;LLUN012288-PA;LLUN000352-PA;LLUN008672-PA;LLUN002541-PA;LLUN009226-PA;LLUN006059-PA;LLUN009434-PA KEGG: 00565+3.1.1.4 Ether lipid metabolism 7 LLUN008242-PA;LLUN003919-PA;LLUN001370-PA;LLUN003536-PA;LLUN001410-PA;LLUN000563-PA;LLUN008580-PA Reactome: R-HSA-163282 Mitochondrial transcription initiation 1 LLUN012163-PA Reactome: R-HSA-69473 G2/M DNA damage checkpoint 14 LLUN007180-PA;LLUN000692-PA;LLUN012395-PA;LLUN008476-PA;LLUN011570-PA;LLUN011163-PA;LLUN010115-PA;LLUN000563-PA;LLUN011433-PA;LLUN010205-PA;LLUN003498-PA;LLUN012021-PA;LLUN012973-PA;LLUN012819-PA Reactome: R-HSA-2453864 Retinoid cycle disease events 1 LLUN009875-PA Reactome: R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 6 LLUN005541-PA;LLUN010032-PA;LLUN000317-PA;LLUN011786-PA;LLUN000167-PA;LLUN012034-PA KEGG: 00790+1.14.16.2 Folate biosynthesis 1 LLUN000709-PA Reactome: R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 2 LLUN005530-PA;LLUN004172-PA Reactome: R-HSA-1236394 Signaling by ERBB4 2 LLUN003650-PA;LLUN000415-PA KEGG: 00520+2.5.1.7 Amino sugar and nucleotide sugar metabolism 1 LLUN000097-PA KEGG: 00051+5.3.1.5 Fructose and mannose metabolism 1 LLUN005109-PA Reactome: R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 30 LLUN012548-PA;LLUN008960-PA;LLUN006525-PA;LLUN003501-PA;LLUN005440-PA;LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN004861-PA;LLUN009994-PA;LLUN006627-PA;LLUN008342-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN002998-PA;LLUN005530-PA;LLUN002894-PA;LLUN000089-PA;LLUN008477-PA;LLUN003629-PA;LLUN013272-PA;LLUN003215-PA;LLUN005030-PA;LLUN010012-PA;LLUN004706-PA;LLUN004508-PA;LLUN004794-PA;LLUN005593-PA;LLUN005610-PA MetaCyc: PWY-7892 Trna-uridine 2-thiolation and selenation (bacteria) 1 LLUN007027-PA KEGG: 00260+2.1.2.1 Glycine, serine and threonine metabolism 3 LLUN006558-PA;LLUN000209-PA;LLUN011129-PA KEGG: 00640+4.2.1.17 Propanoate metabolism 4 LLUN011561-PA;LLUN007706-PA;LLUN008953-PA;LLUN000586-PA Reactome: R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 8 LLUN008802-PA;LLUN008719-PA;LLUN012973-PA;LLUN001634-PA;LLUN007180-PA;LLUN008476-PA;LLUN011570-PA;LLUN009996-PA Reactome: R-HSA-9665249 Resistance of ERBB2 KD mutants to afatinib 2 LLUN008416-PA;LLUN008205-PA Reactome: R-HSA-6782861 Synthesis of wybutosine at G37 of tRNA(Phe) 1 LLUN011248-PA MetaCyc: PWY-8053 Anandamide biosynthesis II 10 LLUN000563-PA;LLUN008580-PA;LLUN001410-PA;LLUN008689-PA;LLUN003919-PA;LLUN000308-PA;LLUN003536-PA;LLUN001370-PA;LLUN003443-PA;LLUN008242-PA MetaCyc: PWY-3581 (S)-reticuline biosynthesis I 1 LLUN000709-PA KEGG: 00471+3.5.1.2 D-Glutamine and D-glutamate metabolism 1 LLUN009510-PA MetaCyc: PWY-6749 CMP-legionaminate biosynthesis I 7 LLUN000282-PA;LLUN000917-PA;LLUN001189-PA;LLUN009369-PA;LLUN001655-PA;LLUN004184-PA;LLUN009017-PA Reactome: R-HSA-5685938 HDR through Single Strand Annealing (SSA) 15 LLUN011570-PA;LLUN008476-PA;LLUN007180-PA;LLUN000692-PA;LLUN000604-PA;LLUN000563-PA;LLUN011163-PA;LLUN010115-PA;LLUN011433-PA;LLUN012021-PA;LLUN003498-PA;LLUN010205-PA;LLUN012973-PA;LLUN002277-PA;LLUN012819-PA Reactome: R-HSA-373753 Nephrin family interactions 1 LLUN008498-PA Reactome: R-HSA-9627069 Regulation of the apoptosome activity 9 LLUN006174-PA;LLUN001057-PA;LLUN002516-PA;LLUN011888-PA;LLUN011140-PA;LLUN006836-PA;LLUN003543-PA;LLUN003801-PA;LLUN000196-PA Reactome: R-HSA-174437 Removal of the Flap Intermediate from the C-strand 5 LLUN008719-PA;LLUN009996-PA;LLUN007180-PA;LLUN008476-PA;LLUN008802-PA KEGG: 00270+1.1.1.37 Cysteine and methionine metabolism 3 LLUN000276-PA;LLUN009867-PA;LLUN012438-PA KEGG: 00670+6.3.4.3 One carbon pool by folate 2 LLUN005962-PA;LLUN011200-PA MetaCyc: PWY-5871 Ubiquinol-9 biosynthesis (eukaryotic) 3 LLUN003684-PA;LLUN000136-PA;LLUN010266-PA Reactome: R-HSA-5626467 RHO GTPases activate IQGAPs 19 LLUN002707-PA;LLUN011466-PA;LLUN001322-PA;LLUN006723-PA;LLUN008923-PA;LLUN003240-PA;LLUN006122-PA;LLUN011766-PA;LLUN009062-PA;LLUN004100-PA;LLUN003553-PA;LLUN006353-PA;LLUN011179-PA;LLUN000039-PA;LLUN003554-PA;LLUN007825-PA;LLUN011465-PA;LLUN003209-PA;LLUN002581-PA Reactome: R-HSA-2393930 Phosphate bond hydrolysis by NUDT proteins 4 LLUN000038-PA;LLUN012300-PA;LLUN003437-PA;LLUN000162-PA MetaCyc: PWY-7674 CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis 4 LLUN012864-PA;LLUN012135-PA;LLUN000102-PA;LLUN000339-PA KEGG: 00770+2.7.1.24 Pantothenate and CoA biosynthesis 3 LLUN000037-PA;LLUN002593-PA;LLUN001090-PA MetaCyc: PWY-7205 CMP phosphorylation 6 LLUN006247-PA;LLUN000213-PA;LLUN011985-PA;LLUN012628-PA;LLUN012009-PA;LLUN012527-PA MetaCyc: PWY-7948 4-oxopentanoate degradation 1 LLUN000585-PA KEGG: 00240+2.7.4.25 Pyrimidine metabolism 1 LLUN012009-PA MetaCyc: PWY-6622 Heptadecane biosynthesis 1 LLUN000161-PA MetaCyc: PWY-5738 GDP-6-deoxy-D-talose biosynthesis 1 LLUN000234-PA Reactome: R-HSA-212676 Dopamine Neurotransmitter Release Cycle 4 LLUN008631-PA;LLUN002146-PA;LLUN011055-PA;LLUN000986-PA KEGG: 00290+1.1.1.86 Valine, leucine and isoleucine biosynthesis 1 LLUN000553-PA KEGG: 00230+2.1.2.2 Purine metabolism 1 LLUN000772-PA KEGG: 00473+6.3.2.4 D-Alanine metabolism 1 LLUN000040-PA Reactome: R-HSA-8849932 Synaptic adhesion-like molecules 1 LLUN008044-PA Reactome: R-HSA-113507 E2F-enabled inhibition of pre-replication complex formation 3 LLUN004644-PA;LLUN004645-PA;LLUN007960-PA MetaCyc: PWY-6277 Superpathway of 5-aminoimidazole ribonucleotide biosynthesis 3 LLUN010077-PA;LLUN006932-PA;LLUN006933-PA MetaCyc: PWY-7007 Methyl ketone biosynthesis (engineered) 4 LLUN011561-PA;LLUN000586-PA;LLUN008953-PA;LLUN007706-PA Reactome: R-HSA-2871837 FCERI mediated NF-kB activation 32 LLUN006111-PA;LLUN009994-PA;LLUN004861-PA;LLUN002054-PA;LLUN006267-PA;LLUN002998-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN007485-PA;LLUN008960-PA;LLUN012548-PA;LLUN005440-PA;LLUN003501-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN008477-PA;LLUN005610-PA;LLUN004794-PA;LLUN000089-PA;LLUN006627-PA;LLUN009980-PA;LLUN008342-PA;LLUN006525-PA;LLUN005030-PA;LLUN013272-PA;LLUN003629-PA;LLUN005593-PA;LLUN004508-PA;LLUN005530-PA;LLUN002894-PA Reactome: R-HSA-432047 Passive transport by Aquaporins 5 LLUN007155-PA;LLUN006576-PA;LLUN010339-PA;LLUN010009-PA;LLUN009589-PA Reactome: R-HSA-174411 Polymerase switching on the C-strand of the telomere 8 LLUN011570-PA;LLUN010178-PA;LLUN004948-PA;LLUN009996-PA;LLUN006991-PA;LLUN001634-PA;LLUN012973-PA;LLUN008719-PA KEGG: 00970+6.1.1.6 Aminoacyl-tRNA biosynthesis 2 LLUN010324-PA;LLUN000150-PA KEGG: 00030+5.3.1.6 Pentose phosphate pathway 2 LLUN000903-PA;LLUN007784-PA Reactome: R-HSA-392451 G beta:gamma signalling through PI3Kgamma 1 LLUN007485-PA Reactome: R-HSA-2395516 Electron transport from NADPH to Ferredoxin 1 LLUN006656-PA MetaCyc: PWY-5532 Nucleoside and nucleotide degradation (archaea) 1 LLUN000578-PA Reactome: R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 9 LLUN012482-PA;LLUN009498-PA;LLUN009496-PA;LLUN009497-PA;LLUN011913-PA;LLUN006200-PA;LLUN008610-PA;LLUN008475-PA;LLUN004997-PA Reactome: R-HSA-5654712 FRS-mediated FGFR4 signaling 1 LLUN002128-PA Reactome: R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 14 LLUN013251-PA;LLUN002890-PA;LLUN010206-PA;LLUN004553-PA;LLUN005965-PA;LLUN007434-PA;LLUN010388-PA;LLUN002905-PA;LLUN011652-PA;LLUN001889-PA;LLUN010510-PA;LLUN012672-PA;LLUN013198-PA;LLUN006640-PA Reactome: R-HSA-196783 Coenzyme A biosynthesis 3 LLUN010650-PA;LLUN000524-PA;LLUN001112-PA KEGG: 00680+5.4.2.12 Methane metabolism 1 LLUN000530-PA KEGG: 00564+3.1.1.32+3.1.1.4 Glycerophospholipid metabolism 1 LLUN000563-PA Reactome: R-HSA-9614657 FOXO-mediated transcription of cell death genes 4 LLUN002498-PA;LLUN008644-PA;LLUN010444-PA;LLUN012190-PA MetaCyc: PWY-5877 Beta-carboline biosynthesis 1 LLUN000568-PA KEGG: 00770+1.1.1.86 Pantothenate and CoA biosynthesis 1 LLUN000553-PA Reactome: R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 52 LLUN003021-PA;LLUN008315-PA;LLUN011966-PA;LLUN006930-PA;LLUN001942-PA;LLUN004396-PA;LLUN004941-PA;LLUN006723-PA;LLUN005991-PA;LLUN011306-PA;LLUN003554-PA;LLUN011307-PA;LLUN003227-PA;LLUN003961-PA;LLUN000700-PA;LLUN009334-PA;LLUN003209-PA;LLUN003020-PA;LLUN002581-PA;LLUN005756-PA;LLUN000702-PA;LLUN009062-PA;LLUN002033-PA;LLUN006353-PA;LLUN010341-PA;LLUN003240-PA;LLUN007801-PA;LLUN002972-PA;LLUN007152-PA;LLUN009960-PA;LLUN002707-PA;LLUN009885-PA;LLUN001322-PA;LLUN008923-PA;LLUN007288-PA;LLUN006124-PA;LLUN005998-PA;LLUN007825-PA;LLUN003258-PA;LLUN002031-PA;LLUN012820-PA;LLUN002147-PA;LLUN004221-PA;LLUN000701-PA;LLUN009505-PA;LLUN008144-PA;LLUN011766-PA;LLUN003553-PA;LLUN004100-PA;LLUN011179-PA;LLUN000039-PA;LLUN008300-PA MetaCyc: PWY-7988 Baumannoferrin biosynthesis 1 LLUN008772-PA MetaCyc: PWY-6672 Cis-genanyl-coa degradation 2 LLUN000254-PA;LLUN001912-PA Reactome: R-HSA-5362517 Signaling by Retinoic Acid 5 LLUN000092-PA;LLUN000533-PA;LLUN000029-PA;LLUN009870-PA;LLUN000314-PA Reactome: R-HSA-211945 Phase I - Functionalization of compounds 3 LLUN008788-PA;LLUN009472-PA;LLUN006996-PA KEGG: 00400+4.2.3.5 Phenylalanine, tyrosine and tryptophan biosynthesis 1 LLUN011560-PA KEGG: 00970+6.1.1.16 Aminoacyl-tRNA biosynthesis 4 LLUN000770-PA;LLUN006888-PA;LLUN004051-PA;LLUN004925-PA MetaCyc: PWY-6613 Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate 4 LLUN011200-PA;LLUN010882-PA;LLUN000772-PA;LLUN000777-PA Reactome: R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 30 LLUN012548-PA;LLUN008960-PA;LLUN006525-PA;LLUN005440-PA;LLUN003501-PA;LLUN009980-PA;LLUN002054-PA;LLUN006267-PA;LLUN004861-PA;LLUN009994-PA;LLUN006627-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN008342-PA;LLUN002998-PA;LLUN005530-PA;LLUN000089-PA;LLUN002894-PA;LLUN003629-PA;LLUN008477-PA;LLUN010012-PA;LLUN003215-PA;LLUN005030-PA;LLUN004706-PA;LLUN013272-PA;LLUN004508-PA;LLUN004794-PA;LLUN005610-PA;LLUN005593-PA Reactome: R-HSA-5685939 HDR through MMEJ (alt-NHEJ) 3 LLUN010205-PA;LLUN008802-PA;LLUN006941-PA KEGG: 04070+2.7.1.107 Phosphatidylinositol signaling system 3 LLUN012411-PA;LLUN001142-PA;LLUN000135-PA KEGG: 00970+6.1.1.19 Aminoacyl-tRNA biosynthesis 2 LLUN010162-PA;LLUN001296-PA KEGG: 00604+3.2.1.52 Glycosphingolipid biosynthesis - ganglio series 6 LLUN003183-PA;LLUN009341-PA;LLUN007651-PA;LLUN010383-PA;LLUN008090-PA;LLUN007975-PA MetaCyc: PWY-7391 Isoprene biosynthesis II (engineered) 4 LLUN007815-PA;LLUN006161-PA;LLUN009836-PA;LLUN006160-PA Reactome: R-HSA-8941856 RUNX3 regulates NOTCH signaling 3 LLUN010444-PA;LLUN002369-PA;LLUN008644-PA Reactome: R-HSA-163359 Glucagon signaling in metabolic regulation 2 LLUN004430-PA;LLUN004610-PA Reactome: R-HSA-198753 ERK/MAPK targets 1 LLUN002516-PA MetaCyc: PWY-7807 Glyphosate degradation III 2 LLUN003630-PA;LLUN000272-PA KEGG: 00600+2.4.1.80 Sphingolipid metabolism 1 LLUN004238-PA Reactome: R-HSA-140342 Apoptosis induced DNA fragmentation 1 LLUN006543-PA KEGG: 00620+1.2.4.1 Pyruvate metabolism 1 LLUN000032-PA MetaCyc: PWY-8051 Anandamide biosynthesis I 10 LLUN000308-PA;LLUN003443-PA;LLUN003536-PA;LLUN001370-PA;LLUN008242-PA;LLUN008580-PA;LLUN000563-PA;LLUN001410-PA;LLUN003919-PA;LLUN008689-PA Reactome: R-HSA-1650814 Collagen biosynthesis and modifying enzymes 3 LLUN004092-PA;LLUN013127-PA;LLUN002886-PA KEGG: 00500+2.4.1.1 Starch and sucrose metabolism 4 LLUN001762-PA;LLUN000295-PA;LLUN000667-PA;LLUN000671-PA Reactome: R-HSA-428890 Role of ABL in ROBO-SLIT signaling 1 LLUN009164-PA Reactome: R-HSA-5693548 Sensing of DNA Double Strand Breaks 1 LLUN010205-PA Reactome: R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 37 LLUN003629-PA;LLUN013272-PA;LLUN005030-PA;LLUN004508-PA;LLUN005593-PA;LLUN005530-PA;LLUN002894-PA;LLUN000848-PA;LLUN009980-PA;LLUN006627-PA;LLUN008342-PA;LLUN012097-PA;LLUN004685-PA;LLUN000845-PA;LLUN007882-PA;LLUN006525-PA;LLUN008477-PA;LLUN003215-PA;LLUN004706-PA;LLUN010012-PA;LLUN004076-PA;LLUN004794-PA;LLUN005610-PA;LLUN012273-PA;LLUN000089-PA;LLUN002054-PA;LLUN006267-PA;LLUN009994-PA;LLUN004861-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN002998-PA;LLUN012548-PA;LLUN008960-PA;LLUN003501-PA;LLUN005440-PA KEGG: 00561+3.2.1.22 Glycerolipid metabolism 4 LLUN005205-PA;LLUN001202-PA;LLUN010776-PA;LLUN007044-PA KEGG: 00564+1.1.5.3 Glycerophospholipid metabolism 2 LLUN000668-PA;LLUN010207-PA MetaCyc: PWY-5054 D-sorbitol biosynthesis I 1 LLUN000137-PA Reactome: R-HSA-5250924 B-WICH complex positively regulates rRNA expression 9 LLUN001676-PA;LLUN009871-PA;LLUN009483-PA;LLUN000521-PA;LLUN011477-PA;LLUN007911-PA;LLUN010529-PA;LLUN001290-PA;LLUN013145-PA MetaCyc: PWY-5744 Glyoxylate assimilation 5 LLUN000178-PA;LLUN005628-PA;LLUN008095-PA;LLUN008096-PA;LLUN006407-PA Reactome: R-HSA-425561 Sodium/Calcium exchangers 12 LLUN001707-PA;LLUN000100-PA;LLUN001705-PA;LLUN001706-PA;LLUN006794-PA;LLUN005562-PA;LLUN001708-PA;LLUN002727-PA;LLUN006696-PA;LLUN002015-PA;LLUN006864-PA;LLUN005561-PA Reactome: R-HSA-168638 NOD1/2 Signaling Pathway 1 LLUN005530-PA Reactome: R-HSA-2453902 The canonical retinoid cycle in rods (twilight vision) 2 LLUN009404-PA;LLUN009875-PA MetaCyc: PWY-5686 UMP biosynthesis I 7 LLUN000049-PA;LLUN013209-PA;LLUN006557-PA;LLUN000087-PA;LLUN009630-PA;LLUN008467-PA;LLUN004225-PA Reactome: R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 3 LLUN009496-PA;LLUN009497-PA;LLUN009498-PA MetaCyc: PWY-5971 Palmitate biosynthesis II (bacteria and plant cytoplasm) 4 LLUN005169-PA;LLUN000184-PA;LLUN000176-PA;LLUN003811-PA Reactome: R-HSA-5656169 Termination of translesion DNA synthesis 12 LLUN008978-PA;LLUN011403-PA;LLUN001634-PA;LLUN008719-PA;LLUN012973-PA;LLUN008476-PA;LLUN011570-PA;LLUN007364-PA;LLUN000779-PA;LLUN005530-PA;LLUN007180-PA;LLUN009996-PA Reactome: R-HSA-204005 COPII-mediated vesicle transport 13 LLUN009459-PA;LLUN008308-PA;LLUN008668-PA;LLUN008147-PA;LLUN011749-PA;LLUN009650-PA;LLUN007816-PA;LLUN010965-PA;LLUN006144-PA;LLUN007899-PA;LLUN011827-PA;LLUN006985-PA;LLUN002935-PA MetaCyc: PWY-5523 5,6-dimethylbenzimidazole biosynthesis I (aerobic) 1 LLUN000051-PA Reactome: R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 10 LLUN008449-PA;LLUN002885-PA;LLUN010670-PA;LLUN008450-PA;LLUN007070-PA;LLUN013020-PA;LLUN006122-PA;LLUN002516-PA;LLUN012891-PA;LLUN007009-PA Reactome: R-HSA-74749 Signal attenuation 1 LLUN002516-PA Reactome: R-HSA-1268020 Mitochondrial protein import 24 LLUN011761-PA;LLUN000257-PA;LLUN007552-PA;LLUN000085-PA;LLUN006879-PA;LLUN000891-PA;LLUN000601-PA;LLUN006496-PA;LLUN000176-PA;LLUN000039-PA;LLUN000136-PA;LLUN000639-PA;LLUN004542-PA;LLUN003543-PA;LLUN000086-PA;LLUN007362-PA;LLUN008347-PA;LLUN012321-PA;LLUN011094-PA;LLUN010981-PA;LLUN008537-PA;LLUN000501-PA;LLUN001187-PA;LLUN007514-PA MetaCyc: PWY-6802 Salidroside biosynthesis 1 LLUN012888-PA MetaCyc: PWY-7798 Protein S-nitrosylation and denitrosylation 1 LLUN012888-PA KEGG: 00400+4.1.3.27 Phenylalanine, tyrosine and tryptophan biosynthesis 2 LLUN000681-PA;LLUN012019-PA Reactome: R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 1 LLUN005530-PA Reactome: R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 2 LLUN007704-PA;LLUN005530-PA Reactome: R-HSA-1483101 Synthesis of PS 1 LLUN001255-PA MetaCyc: PWY-3821 D-galactose detoxification 2 LLUN004037-PA;LLUN003916-PA MetaCyc: PWY-5697 Allantoin degradation to ureidoglycolate I (urea producing) 1 LLUN006292-PA Reactome: R-HSA-9665250 Resistance of ERBB2 KD mutants to AEE788 2 LLUN008416-PA;LLUN008205-PA KEGG: 00720+2.7.2.1 Carbon fixation pathways in prokaryotes 2 LLUN007189-PA;LLUN009622-PA MetaCyc: PWY-6664 Di-myo-inositol phosphate biosynthesis 1 LLUN006316-PA MetaCyc: PWY-8001 Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis 3 LLUN000193-PA;LLUN000741-PA;LLUN001088-PA Reactome: R-HSA-4549356 Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 2 LLUN011947-PA;LLUN000042-PA MetaCyc: PWY-7883 Anhydromuropeptides recycling II 7 LLUN008090-PA;LLUN007975-PA;LLUN010383-PA;LLUN000274-PA;LLUN007651-PA;LLUN009341-PA;LLUN003183-PA KEGG: 00710+4.1.2.13 Carbon fixation in photosynthetic organisms 3 LLUN000832-PA;LLUN011949-PA;LLUN000906-PA Reactome: R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 31 LLUN003215-PA;LLUN004706-PA;LLUN005030-PA;LLUN010012-PA;LLUN013272-PA;LLUN008477-PA;LLUN003629-PA;LLUN005610-PA;LLUN005593-PA;LLUN004794-PA;LLUN004508-PA;LLUN005530-PA;LLUN000089-PA;LLUN002894-PA;LLUN006111-PA;LLUN004861-PA;LLUN009994-PA;LLUN006627-PA;LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN008342-PA;LLUN008960-PA;LLUN012548-PA;LLUN005440-PA;LLUN003501-PA;LLUN006525-PA KEGG: 00053+1.8.5.1 Ascorbate and aldarate metabolism 2 LLUN008086-PA;LLUN008487-PA Reactome: R-HSA-9619483 Activation of AMPK downstream of NMDARs 17 LLUN006723-PA;LLUN008923-PA;LLUN002707-PA;LLUN001322-PA;LLUN003047-PA;LLUN003240-PA;LLUN003553-PA;LLUN011766-PA;LLUN009062-PA;LLUN004100-PA;LLUN011179-PA;LLUN006353-PA;LLUN000039-PA;LLUN003209-PA;LLUN002581-PA;LLUN003554-PA;LLUN007825-PA MetaCyc: PWY-7836 Ganglio-series glycosphingolipids biosynthesis 1 LLUN004238-PA Reactome: R-HSA-5419276 Mitochondrial translation termination 38 LLUN009134-PA;LLUN005651-PA;LLUN010900-PA;LLUN011356-PA;LLUN012749-PA;LLUN010361-PA;LLUN000268-PA;LLUN010333-PA;LLUN008500-PA;LLUN006698-PA;LLUN009752-PA;LLUN005934-PA;LLUN008289-PA;LLUN008596-PA;LLUN003194-PA;LLUN000171-PA;LLUN000285-PA;LLUN010363-PA;LLUN009707-PA;LLUN000277-PA;LLUN008084-PA;LLUN004962-PA;LLUN000540-PA;LLUN000334-PA;LLUN012172-PA;LLUN000761-PA;LLUN011566-PA;LLUN006713-PA;LLUN008265-PA;LLUN008128-PA;LLUN000269-PA;LLUN001413-PA;LLUN007922-PA;LLUN008324-PA;LLUN000336-PA;LLUN008073-PA;LLUN012315-PA;LLUN006358-PA KEGG: 00600+3.5.1.23 Sphingolipid metabolism 1 LLUN009763-PA MetaCyc: PWY-5177 Glutaryl-coa degradation 4 LLUN007706-PA;LLUN000586-PA;LLUN008953-PA;LLUN011561-PA Reactome: R-HSA-1660661 Sphingolipid de novo biosynthesis 3 LLUN005487-PA;LLUN010031-PA;LLUN007731-PA KEGG: 00680+1.17.1.9 Methane metabolism 1 LLUN009876-PA MetaCyc: PWY-181 Photorespiration 3 LLUN000209-PA;LLUN011129-PA;LLUN006558-PA Reactome: R-HSA-5545483 Defective Mismatch Repair Associated With MLH1 1 LLUN002096-PA Reactome: R-HSA-3299685 Detoxification of Reactive Oxygen Species 31 LLUN000660-PA;LLUN007765-PA;LLUN010426-PA;LLUN000412-PA;LLUN012102-PA;LLUN011445-PA;LLUN011898-PA;LLUN005394-PA;LLUN000547-PA;LLUN000742-PA;LLUN001792-PA;LLUN006836-PA;LLUN001796-PA;LLUN000557-PA;LLUN003801-PA;LLUN005006-PA;LLUN000578-PA;LLUN008395-PA;LLUN006174-PA;LLUN002757-PA;LLUN008940-PA;LLUN011977-PA;LLUN006719-PA;LLUN001208-PA;LLUN012501-PA;LLUN009614-PA;LLUN003543-PA;LLUN011888-PA;LLUN005708-PA;LLUN011140-PA;LLUN010402-PA KEGG: 00240+6.3.5.5 Pyrimidine metabolism 2 LLUN000049-PA;LLUN009630-PA Reactome: R-HSA-1482788 Acyl chain remodelling of PC 4 LLUN003919-PA;LLUN003536-PA;LLUN001410-PA;LLUN008580-PA KEGG: 00680+1.1.1.37 Methane metabolism 3 LLUN012438-PA;LLUN009867-PA;LLUN000276-PA Reactome: R-HSA-110330 Recognition and association of DNA glycosylase with site containing an affected purine 2 LLUN000526-PA;LLUN005053-PA KEGG: 00270+3.3.1.1 Cysteine and methionine metabolism 3 LLUN012556-PA;LLUN007534-PA;LLUN008420-PA KEGG: 00620+2.3.1.8 Pyruvate metabolism 2 LLUN000223-PA;LLUN007189-PA Reactome: R-HSA-190873 Gap junction degradation 4 LLUN006792-PA;LLUN011753-PA;LLUN011540-PA;LLUN007814-PA Reactome: R-HSA-5610787 Hedgehog 'off' state 3 LLUN004430-PA;LLUN004298-PA;LLUN004610-PA Reactome: R-HSA-114604 GPVI-mediated activation cascade 3 LLUN006122-PA;LLUN007485-PA;LLUN006897-PA Reactome: R-HSA-1251985 Nuclear signaling by ERBB4 3 LLUN001957-PA;LLUN007104-PA;LLUN003449-PA KEGG: 00520+2.7.1.2 Amino sugar and nucleotide sugar metabolism 1 LLUN009874-PA Reactome: R-HSA-6803157 Antimicrobial peptides 6 LLUN000439-PA;LLUN003517-PA;LLUN002035-PA;LLUN008551-PA;LLUN002036-PA;LLUN008552-PA MetaCyc: PWY-7222 Guanosine deoxyribonucleotides de novo biosynthesis II 7 LLUN006247-PA;LLUN000213-PA;LLUN008193-PA;LLUN011985-PA;LLUN012628-PA;LLUN012527-PA;LLUN001080-PA MetaCyc: PWY-6643 Coenzyme M biosynthesis II 1 LLUN009219-PA Reactome: R-HSA-6783984 Glycine degradation 7 LLUN010254-PA;LLUN008679-PA;LLUN008929-PA;LLUN000899-PA;LLUN000900-PA;LLUN000029-PA;LLUN003018-PA KEGG: 00400+4.2.1.20 Phenylalanine, tyrosine and tryptophan biosynthesis 1 LLUN012017-PA MetaCyc: PWY-6369 Inositol diphosphates biosynthesis 1 LLUN006346-PA KEGG: 00051+5.3.1.6 Fructose and mannose metabolism 2 LLUN000903-PA;LLUN007784-PA KEGG: 00400+4.1.1.48 Phenylalanine, tyrosine and tryptophan biosynthesis 1 LLUN012018-PA Reactome: R-HSA-1663150 The activation of arylsulfatases 1 LLUN002778-PA KEGG: 00660+2.2.1.6 C5-Branched dibasic acid metabolism 2 LLUN000551-PA;LLUN000044-PA Reactome: R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 11 LLUN000563-PA;LLUN011163-PA;LLUN000692-PA;LLUN006020-PA;LLUN012819-PA;LLUN012760-PA;LLUN011433-PA;LLUN002154-PA;LLUN000062-PA;LLUN003498-PA;LLUN010205-PA Reactome: R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 14 LLUN001889-PA;LLUN008923-PA;LLUN013198-PA;LLUN006353-PA;LLUN011766-PA;LLUN009062-PA;LLUN007825-PA;LLUN013251-PA;LLUN010206-PA;LLUN003240-PA;LLUN004553-PA;LLUN002905-PA;LLUN010388-PA;LLUN011652-PA KEGG: 00061+1.3.1.9 Fatty acid biosynthesis 1 LLUN003811-PA MetaCyc: PWY-6363 D-myo-inositol (1,4,5)-trisphosphate degradation 2 LLUN000211-PA;LLUN003712-PA Reactome: R-HSA-5673001 RAF/MAP kinase cascade 5 LLUN002516-PA;LLUN000021-PA;LLUN011839-PA;LLUN002128-PA;LLUN008044-PA MetaCyc: PWY-5076 L-leucine degradation III 1 LLUN012888-PA Reactome: R-HSA-1362409 Mitochondrial iron-sulfur cluster biogenesis 5 LLUN000922-PA;LLUN010981-PA;LLUN006496-PA;LLUN012542-PA;LLUN004985-PA KEGG: 00220+3.5.1.2 Arginine biosynthesis 1 LLUN009510-PA KEGG: 00480+2.5.1.18+1.8.5.1 Glutathione metabolism 2 LLUN008487-PA;LLUN008086-PA KEGG: 00550+2.4.1.129+3.4.16.4 Peptidoglycan biosynthesis 2 LLUN011710-PA;LLUN000674-PA MetaCyc: PWY-5078 L-isoleucine degradation II 1 LLUN012888-PA Reactome: R-HSA-1257604 PIP3 activates AKT signaling 7 LLUN004283-PA;LLUN000021-PA;LLUN006440-PA;LLUN006897-PA;LLUN012849-PA;LLUN011192-PA;LLUN007485-PA Reactome: R-HSA-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX) 7 LLUN005398-PA;LLUN000005-PA;LLUN003868-PA;LLUN013118-PA;LLUN000428-PA;LLUN007499-PA;LLUN004711-PA Reactome: R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 2 LLUN004610-PA;LLUN004430-PA MetaCyc: PWY-5041 S-adenosyl-L-methionine cycle II 8 LLUN004715-PA;LLUN002440-PA;LLUN007534-PA;LLUN008420-PA;LLUN000910-PA;LLUN000578-PA;LLUN012556-PA;LLUN009623-PA KEGG: 00670+2.1.2.2 One carbon pool by folate 1 LLUN000772-PA Reactome: R-HSA-416482 G alpha (12/13) signalling events 5 LLUN001551-PA;LLUN012841-PA;LLUN003829-PA;LLUN008793-PA;LLUN003356-PA MetaCyc: PWY-4302 Aerobic respiration III (alternative oxidase pathway) 4 LLUN008348-PA;LLUN011041-PA;LLUN012663-PA;LLUN000260-PA KEGG: 00511+3.2.1.23 Other glycan degradation 4 LLUN010751-PA;LLUN000905-PA;LLUN000904-PA;LLUN001229-PA Reactome: R-HSA-6791461 RPIA deficiency: failed conversion of RU5P to R5P 2 LLUN007784-PA;LLUN000903-PA Reactome: R-HSA-212300 PRC2 methylates histones and DNA 3 LLUN007122-PA;LLUN005292-PA;LLUN001605-PA KEGG: 00230+4.6.1.1 Purine metabolism 3 LLUN004610-PA;LLUN004430-PA;LLUN000148-PA KEGG: 00240+4.1.1.23 Pyrimidine metabolism 1 LLUN006557-PA KEGG: 00460+3.5.1.1 Cyanoamino acid metabolism 1 LLUN010752-PA KEGG: 00592+4.2.1.17 alpha-Linolenic acid metabolism 4 LLUN011561-PA;LLUN008953-PA;LLUN000586-PA;LLUN007706-PA Reactome: R-HSA-2022377 Metabolism of Angiotensinogen to Angiotensins 9 LLUN012417-PA;LLUN009180-PA;LLUN008991-PA;LLUN004179-PA;LLUN004178-PA;LLUN010136-PA;LLUN005102-PA;LLUN001233-PA;LLUN001268-PA KEGG: 00020+4.2.1.2 Citrate cycle (TCA cycle) 3 LLUN012634-PA;LLUN000255-PA;LLUN005021-PA Reactome: R-HSA-3560783 Defective B4GALT7 causes EDS, progeroid type 2 LLUN002060-PA;LLUN004191-PA KEGG: 00270+2.5.1.6 Cysteine and methionine metabolism 3 LLUN002440-PA;LLUN009623-PA;LLUN000910-PA Reactome: R-HSA-170670 Adenylate cyclase inhibitory pathway 2 LLUN004610-PA;LLUN004430-PA KEGG: 00260+1.1.1.103 Glycine, serine and threonine metabolism 1 LLUN000528-PA Reactome: R-HSA-202433 Generation of second messenger molecules 2 LLUN004409-PA;LLUN008470-PA Reactome: R-HSA-110381 Resolution of AP sites via the single-nucleotide replacement pathway 1 LLUN006941-PA MetaCyc: PWY-702 L-methionine biosynthesis II (plants) 3 LLUN000578-PA;LLUN000541-PA;LLUN004715-PA Reactome: R-HSA-9604323 Negative regulation of NOTCH4 signaling 29 LLUN008960-PA;LLUN003501-PA;LLUN005440-PA;LLUN006525-PA;LLUN006627-PA;LLUN009994-PA;LLUN004861-PA;LLUN006111-PA;LLUN002054-PA;LLUN009980-PA;LLUN002998-PA;LLUN008342-PA;LLUN010393-PA;LLUN011115-PA;LLUN012429-PA;LLUN005530-PA;LLUN002894-PA;LLUN000089-PA;LLUN013272-PA;LLUN003215-PA;LLUN010012-PA;LLUN005030-PA;LLUN004706-PA;LLUN003629-PA;LLUN008477-PA;LLUN005593-PA;LLUN005610-PA;LLUN004508-PA;LLUN004794-PA Reactome: R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 13 LLUN001676-PA;LLUN007985-PA;LLUN009871-PA;LLUN000521-PA;LLUN007829-PA;LLUN005850-PA;LLUN011849-PA;LLUN001167-PA;LLUN006359-PA;LLUN007911-PA;LLUN010245-PA;LLUN001290-PA;LLUN003293-PA MetaCyc: PWY-7999 Vitamin K-epoxide cycle 2 LLUN009130-PA;LLUN001642-PA MetaCyc: PWY-7922 Protein O-mannosylation II (mammals, core M1 and core M2) 5 LLUN006904-PA;LLUN008266-PA;LLUN006126-PA;LLUN004509-PA;LLUN004843-PA KEGG: 00240+3.6.1.9 Pyrimidine metabolism 3 LLUN000110-PA;LLUN006214-PA;LLUN003890-PA KEGG: 00020+1.1.1.37 Citrate cycle (TCA cycle) 3 LLUN009867-PA;LLUN000276-PA;LLUN012438-PA Reactome: R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 19 LLUN003240-PA;LLUN008044-PA;LLUN002146-PA;LLUN001322-PA;LLUN002707-PA;LLUN006723-PA;LLUN008923-PA;LLUN007825-PA;LLUN003554-PA;LLUN003209-PA;LLUN002581-PA;LLUN011839-PA;LLUN011179-PA;LLUN006353-PA;LLUN000039-PA;LLUN011766-PA;LLUN004100-PA;LLUN009062-PA;LLUN003553-PA MetaCyc: PWY-8010 L-cysteine biosynthesis IX (Trichomonas vaginalis) 3 LLUN011489-PA;LLUN000776-PA;LLUN012010-PA KEGG: 00563+2.4.1.198 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 1 LLUN007791-PA KEGG: 00710+1.1.1.37 Carbon fixation in photosynthetic organisms 3 LLUN009867-PA;LLUN000276-PA;LLUN012438-PA KEGG: 00790+1.5.1.3 Folate biosynthesis 1 LLUN010048-PA KEGG: 00230+2.7.6.1 Purine metabolism 3 LLUN004011-PA;LLUN009897-PA;LLUN004009-PA Reactome: R-HSA-3371453 Regulation of HSF1-mediated heat shock response 63 LLUN008721-PA;LLUN007180-PA;LLUN002658-PA;LLUN008284-PA;LLUN012814-PA;LLUN003664-PA;LLUN009733-PA;LLUN006827-PA;LLUN007979-PA;LLUN006872-PA;LLUN003877-PA;LLUN012529-PA;LLUN010831-PA;LLUN013269-PA;LLUN008476-PA;LLUN006248-PA;LLUN009166-PA;LLUN006249-PA;LLUN011573-PA;LLUN010145-PA;LLUN013000-PA;LLUN004079-PA;LLUN008283-PA;LLUN002516-PA;LLUN008961-PA;LLUN004315-PA;LLUN003092-PA;LLUN006250-PA;LLUN006405-PA;LLUN003887-PA;LLUN011857-PA;LLUN006062-PA;LLUN009463-PA;LLUN011694-PA;LLUN004098-PA;LLUN003885-PA;LLUN010820-PA;LLUN009756-PA;LLUN008720-PA;LLUN002822-PA;LLUN012305-PA;LLUN001776-PA;LLUN005781-PA;LLUN002821-PA;LLUN008894-PA;LLUN012753-PA;LLUN001860-PA;LLUN004875-PA;LLUN003064-PA;LLUN004096-PA;LLUN004780-PA;LLUN000054-PA;LLUN003665-PA;LLUN007599-PA;LLUN000985-PA;LLUN004789-PA;LLUN003438-PA;LLUN001300-PA;LLUN002650-PA;LLUN010420-PA;LLUN010242-PA;LLUN008374-PA;LLUN012440-PA Reactome: R-HSA-2024096 HS-GAG degradation 5 LLUN004191-PA;LLUN002060-PA;LLUN011339-PA;LLUN000905-PA;LLUN010751-PA Reactome: R-HSA-5607763 CLEC7A (Dectin-1) induces NFAT activation 1 LLUN004972-PA KEGG: 00230+3.1.4.53 Purine metabolism 2 LLUN000305-PA;LLUN005060-PA KEGG: 00430+1.4.1.1 Taurine and hypotaurine metabolism 1 LLUN013118-PA Reactome: R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 3 LLUN006991-PA;LLUN004948-PA;LLUN010178-PA MetaCyc: PWY-5097 L-lysine biosynthesis VI 2 LLUN012256-PA;LLUN000049-PA KEGG: 00240+2.7.4.14 Pyrimidine metabolism 1 LLUN006609-PA Reactome: R-HSA-525793 Myogenesis 4 LLUN003612-PA;LLUN006122-PA;LLUN008048-PA;LLUN003613-PA KEGG: 00430+2.3.1.8 Taurine and hypotaurine metabolism 2 LLUN007189-PA;LLUN000223-PA KEGG: 00620+1.8.1.4 Pyruvate metabolism 1 LLUN000029-PA MetaCyc: PWY-7179-1 Purine deoxyribonucleosides degradation II 2 LLUN004537-PA;LLUN000578-PA KEGG: 00260+1.1.1.81 Glycine, serine and threonine metabolism 1 LLUN001199-PA MetaCyc: PWY-7356 Thiamine salvage IV (yeast) 1 LLUN000288-PA KEGG: 00670+2.1.2.1 One carbon pool by folate 3 LLUN011129-PA;LLUN000209-PA;LLUN006558-PA KEGG: 00010+2.7.1.40 Glycolysis / Gluconeogenesis 2 LLUN013179-PA;LLUN007408-PA Reactome: R-HSA-1474228 Degradation of the extracellular matrix 3 LLUN003267-PA;LLUN001539-PA;LLUN001538-PA Reactome: R-HSA-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus 3 LLUN007104-PA;LLUN003449-PA;LLUN001957-PA KEGG: 00240+3.1.3.5 Pyrimidine metabolism 1 LLUN000322-PA Reactome: R-HSA-1483166 Synthesis of PA 10 LLUN008432-PA;LLUN003536-PA;LLUN010207-PA;LLUN000668-PA;LLUN011702-PA;LLUN012166-PA;LLUN000308-PA;LLUN008689-PA;LLUN008580-PA;LLUN001410-PA Reactome: R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 2 LLUN010402-PA;LLUN001208-PA MetaCyc: PWY-7285 Methylwyosine biosynthesis 3 LLUN000335-PA;LLUN001126-PA;LLUN011248-PA Reactome: R-HSA-5357905 Regulation of TNFR1 signaling 3 LLUN005530-PA;LLUN004187-PA;LLUN004188-PA KEGG: 00230+6.3.3.1 Purine metabolism 1 LLUN006932-PA Reactome: R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 4 LLUN001565-PA;LLUN010602-PA;LLUN009748-PA;LLUN006962-PA Reactome: R-HSA-6804758 Regulation of TP53 Activity through Acetylation 1 LLUN000874-PA Reactome: R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 3 LLUN005530-PA;LLUN004188-PA;LLUN004187-PA KEGG: 00660+1.1.1.85 C5-Branched dibasic acid metabolism 1 LLUN000046-PA MetaCyc: PWY-7039 Phosphatidate metabolism, as a signaling molecule 7 LLUN008499-PA;LLUN012411-PA;LLUN011702-PA;LLUN004409-PA;LLUN000135-PA;LLUN001142-PA;LLUN007371-PA MetaCyc: PWY-7822 Chitin degradation III (Serratia) 15 LLUN001719-PA;LLUN004333-PA;LLUN000048-PA;LLUN006418-PA;LLUN007221-PA;LLUN009014-PA;LLUN010383-PA;LLUN008090-PA;LLUN007975-PA;LLUN003183-PA;LLUN007726-PA;LLUN005932-PA;LLUN007651-PA;LLUN005795-PA;LLUN009341-PA MetaCyc: PWY-5664 Erythro-tetrahydrobiopterin biosynthesis II 3 LLUN012034-PA;LLUN005541-PA;LLUN010032-PA MetaCyc: PWY-6883 Pyruvate fermentation to butanol II (engineered) 4 LLUN007706-PA;LLUN008953-PA;LLUN000586-PA;LLUN011561-PA MetaCyc: PWY-1187 Glucosinolate biosynthesis from homomethionine 1 LLUN000310-PA Reactome: R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 30 LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN009994-PA;LLUN004861-PA;LLUN006627-PA;LLUN008342-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN002998-PA;LLUN012548-PA;LLUN008960-PA;LLUN006525-PA;LLUN003501-PA;LLUN005440-PA;LLUN008477-PA;LLUN003629-PA;LLUN013272-PA;LLUN003215-PA;LLUN005030-PA;LLUN010012-PA;LLUN004706-PA;LLUN004508-PA;LLUN004794-PA;LLUN005593-PA;LLUN005610-PA;LLUN005530-PA;LLUN002894-PA;LLUN000089-PA KEGG: 00500+3.2.1.28 Starch and sucrose metabolism 1 LLUN009110-PA KEGG: 00780+6.3.4.15 Biotin metabolism 1 LLUN008045-PA Reactome: R-HSA-5579007 Defective ACY1 causes encephalopathy 1 LLUN010503-PA Reactome: R-HSA-167590 Nef Mediated CD4 Down-regulation 1 LLUN004638-PA KEGG: 00562+5.3.1.1 Inositol phosphate metabolism 2 LLUN000535-PA;LLUN009807-PA Reactome: R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 82 LLUN004220-PA;LLUN012333-PA;LLUN012719-PA;LLUN008434-PA;LLUN009969-PA;LLUN004648-PA;LLUN009774-PA;LLUN010358-PA;LLUN005530-PA;LLUN009998-PA;LLUN010802-PA;LLUN004909-PA;LLUN010136-PA;LLUN008995-PA;LLUN005954-PA;LLUN000340-PA;LLUN000570-PA;LLUN007563-PA;LLUN006279-PA;LLUN001569-PA;LLUN009177-PA;LLUN009419-PA;LLUN003745-PA;LLUN010153-PA;LLUN002287-PA;LLUN011174-PA;LLUN007733-PA;LLUN007661-PA;LLUN000334-PA;LLUN012495-PA;LLUN002787-PA;LLUN012474-PA;LLUN012000-PA;LLUN011304-PA;LLUN006774-PA;LLUN004837-PA;LLUN012427-PA;LLUN001670-PA;LLUN006863-PA;LLUN003373-PA;LLUN002560-PA;LLUN008530-PA;LLUN006512-PA;LLUN001397-PA;LLUN008357-PA;LLUN008564-PA;LLUN005647-PA;LLUN012390-PA;LLUN005586-PA;LLUN005822-PA;LLUN007812-PA;LLUN004193-PA;LLUN010736-PA;LLUN010052-PA;LLUN000494-PA;LLUN001256-PA;LLUN005442-PA;LLUN003780-PA;LLUN002390-PA;LLUN012611-PA;LLUN008597-PA;LLUN008152-PA;LLUN010350-PA;LLUN003033-PA;LLUN006098-PA;LLUN003515-PA;LLUN008433-PA;LLUN003524-PA;LLUN005084-PA;LLUN003497-PA;LLUN005594-PA;LLUN007100-PA;LLUN000493-PA;LLUN006093-PA;LLUN012076-PA;LLUN004402-PA;LLUN012053-PA;LLUN000856-PA;LLUN007972-PA;LLUN004112-PA;LLUN001675-PA;LLUN001075-PA KEGG: 00643+3.7.1.2 Styrene degradation 1 LLUN005637-PA MetaCyc: PWY-8011 L-serine biosynthesis II 1 LLUN001199-PA KEGG: 00532+2.4.2.26 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 1 LLUN011872-PA Reactome: R-HSA-8948747 Regulation of PTEN localization 1 LLUN005530-PA KEGG: 00270+3.1.3.77 Cysteine and methionine metabolism 1 LLUN000196-PA KEGG: 00240+3.5.4.5 Pyrimidine metabolism 1 LLUN012848-PA KEGG: 00627+4.2.1.17 Aminobenzoate degradation 4 LLUN011561-PA;LLUN007706-PA;LLUN008953-PA;LLUN000586-PA MetaCyc: PWY-7664 Oleate biosynthesis IV (anaerobic) 4 LLUN003811-PA;LLUN005169-PA;LLUN000184-PA;LLUN000176-PA Reactome: R-HSA-5617833 Cilium Assembly 16 LLUN003240-PA;LLUN006723-PA;LLUN008923-PA;LLUN002707-PA;LLUN001322-PA;LLUN002581-PA;LLUN003209-PA;LLUN003554-PA;LLUN007825-PA;LLUN011766-PA;LLUN009062-PA;LLUN004100-PA;LLUN003553-PA;LLUN011179-PA;LLUN006353-PA;LLUN000039-PA KEGG: 00790+4.2.1.96 Folate biosynthesis 1 LLUN008319-PA MetaCyc: PWY-7656 Spodoptera littoralis pheromone biosynthesis 13 LLUN004653-PA;LLUN011511-PA;LLUN007706-PA;LLUN007115-PA;LLUN007057-PA;LLUN010659-PA;LLUN012272-PA;LLUN011561-PA;LLUN008939-PA;LLUN008953-PA;LLUN000586-PA;LLUN003549-PA;LLUN002150-PA Reactome: R-HSA-3359467 Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE 2 LLUN000281-PA;LLUN000141-PA KEGG: 00332+1.2.1.41 Carbapenem biosynthesis 2 LLUN000200-PA;LLUN010744-PA KEGG: 00740+2.7.1.26 Riboflavin metabolism 1 LLUN000051-PA Reactome: R-HSA-3322077 Glycogen synthesis 4 LLUN005530-PA;LLUN008754-PA;LLUN009234-PA;LLUN002260-PA Reactome: R-HSA-5083633 Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 3 LLUN008266-PA;LLUN004509-PA;LLUN013133-PA Reactome: R-HSA-2142753 Arachidonic acid metabolism 1 LLUN004241-PA KEGG: 00540+2.4.1.182 Lipopolysaccharide biosynthesis 1 LLUN000177-PA MetaCyc: PWY-6842 Glutathione-mediated detoxification II 6 LLUN008487-PA;LLUN000310-PA;LLUN000741-PA;LLUN000193-PA;LLUN008086-PA;LLUN001088-PA Reactome: R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 1 LLUN005530-PA MetaCyc: PWY-8043 Ophthalmate biosynthesis 6 LLUN012049-PA;LLUN008974-PA;LLUN009565-PA;LLUN008975-PA;LLUN007915-PA;LLUN000913-PA KEGG: 00260+2.6.1.76 Glycine, serine and threonine metabolism 1 LLUN008772-PA KEGG: 00230+2.7.1.25 Purine metabolism 1 LLUN000320-PA KEGG: 00030+5.1.3.1 Pentose phosphate pathway 2 LLUN010698-PA;LLUN010699-PA Reactome: R-HSA-4551638 SUMOylation of chromatin organization proteins 12 LLUN012529-PA;LLUN008894-PA;LLUN010831-PA;LLUN013269-PA;LLUN008374-PA;LLUN001945-PA;LLUN004789-PA;LLUN003438-PA;LLUN001776-PA;LLUN007599-PA;LLUN005292-PA;LLUN001860-PA Reactome: R-HSA-68877 Mitotic Prometaphase 23 LLUN002475-PA;LLUN003240-PA;LLUN006723-PA;LLUN008923-PA;LLUN002707-PA;LLUN010831-PA;LLUN001322-PA;LLUN009963-PA;LLUN003209-PA;LLUN002581-PA;LLUN004221-PA;LLUN011378-PA;LLUN003554-PA;LLUN007825-PA;LLUN003553-PA;LLUN004100-PA;LLUN009062-PA;LLUN011766-PA;LLUN003438-PA;LLUN009748-PA;LLUN006353-PA;LLUN011179-PA;LLUN000039-PA MetaCyc: PWY-6992 1,5-anhydrofructose degradation 2 LLUN000137-PA;LLUN011806-PA KEGG: 00500+2.4.1.18 Starch and sucrose metabolism 6 LLUN006388-PA;LLUN003576-PA;LLUN009050-PA;LLUN009049-PA;LLUN002260-PA;LLUN003575-PA MetaCyc: PWY-8106 Queuosine biosynthesis III (queuosine salvage) 3 LLUN000743-PA;LLUN000263-PA;LLUN002433-PA Reactome: R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 10 LLUN007599-PA;LLUN001860-PA;LLUN013269-PA;LLUN008374-PA;LLUN012529-PA;LLUN008894-PA;LLUN010831-PA;LLUN003438-PA;LLUN001776-PA;LLUN004789-PA KEGG: 00230+1.7.3.3 Purine metabolism 1 LLUN007804-PA MetaCyc: PWY-7765 3-hydroxy-4-methyl-anthranilate biosynthesis II 1 LLUN004035-PA Reactome: R-HSA-8866423 VLDL assembly 2 LLUN013210-PA;LLUN006216-PA Reactome: R-HSA-8853659 RET signaling 1 LLUN006897-PA Reactome: R-HSA-156842 Eukaryotic Translation Elongation 4 LLUN001375-PA;LLUN000823-PA;LLUN011145-PA;LLUN010454-PA MetaCyc: PWY-7833 Biosynthesis of Lewis epitopes (H. pylori) 1 LLUN012521-PA Reactome: R-HSA-6790901 rRNA modification in the nucleus and cytosol 25 LLUN007741-PA;LLUN012229-PA;LLUN007574-PA;LLUN003033-PA;LLUN008955-PA;LLUN011059-PA;LLUN002357-PA;LLUN002089-PA;LLUN011064-PA;LLUN008545-PA;LLUN010723-PA;LLUN007120-PA;LLUN007834-PA;LLUN009405-PA;LLUN004620-PA;LLUN012517-PA;LLUN010530-PA;LLUN006875-PA;LLUN006232-PA;LLUN006028-PA;LLUN008601-PA;LLUN007812-PA;LLUN004004-PA;LLUN012528-PA;LLUN004390-PA MetaCyc: PWY-1622 Formaldehyde assimilation I (serine pathway) 11 LLUN009867-PA;LLUN000276-PA;LLUN006558-PA;LLUN010054-PA;LLUN008352-PA;LLUN001199-PA;LLUN012438-PA;LLUN000543-PA;LLUN011129-PA;LLUN012182-PA;LLUN000209-PA MetaCyc: PWY-7400 L-arginine biosynthesis IV (archaebacteria) 10 LLUN000544-PA;LLUN000546-PA;LLUN000085-PA;LLUN009630-PA;LLUN000151-PA;LLUN008409-PA;LLUN000086-PA;LLUN000049-PA;LLUN000545-PA;LLUN002360-PA MetaCyc: PWY-561 Superpathway of glyoxylate cycle and fatty acid degradation 10 LLUN009867-PA;LLUN000276-PA;LLUN008348-PA;LLUN012663-PA;LLUN011041-PA;LLUN012438-PA;LLUN012634-PA;LLUN005021-PA;LLUN000260-PA;LLUN000255-PA Reactome: R-HSA-5083630 Defective LFNG causes SCDO3 1 LLUN003131-PA Reactome: R-HSA-4641257 Degradation of AXIN 30 LLUN003501-PA;LLUN005440-PA;LLUN006525-PA;LLUN008960-PA;LLUN012548-PA;LLUN002998-PA;LLUN008342-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN009994-PA;LLUN004861-PA;LLUN006627-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA;LLUN002894-PA;LLUN000089-PA;LLUN005530-PA;LLUN005593-PA;LLUN005610-PA;LLUN004794-PA;LLUN004508-PA;LLUN013272-PA;LLUN005030-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN008477-PA;LLUN003629-PA MetaCyc: PWY-6118 Glycerol-3-phosphate shuttle 2 LLUN000668-PA;LLUN010207-PA Reactome: R-HSA-1475029 Reversible hydration of carbon dioxide 3 LLUN008095-PA;LLUN008096-PA;LLUN006407-PA KEGG: 00280+2.3.3.10 Valine, leucine and isoleucine degradation 1 LLUN007815-PA MetaCyc: PWY-6999 Theophylline degradation 1 LLUN009431-PA MetaCyc: PWY-6829 Trna methylation (yeast) 8 LLUN000335-PA;LLUN000458-PA;LLUN011248-PA;LLUN010826-PA;LLUN013214-PA;LLUN001126-PA;LLUN006541-PA;LLUN002297-PA Reactome: R-HSA-389357 CD28 dependent PI3K/Akt signaling 6 LLUN004283-PA;LLUN006897-PA;LLUN006440-PA;LLUN012849-PA;LLUN011192-PA;LLUN007485-PA Reactome: R-HSA-9665233 Resistance of ERBB2 KD mutants to trastuzumab 2 LLUN008205-PA;LLUN008416-PA Reactome: R-HSA-5334118 DNA methylation 2 LLUN001605-PA;LLUN007122-PA Reactome: R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 10 LLUN003438-PA;LLUN001776-PA;LLUN004789-PA;LLUN013269-PA;LLUN008374-PA;LLUN012529-PA;LLUN008894-PA;LLUN010831-PA;LLUN001860-PA;LLUN007599-PA MetaCyc: PWY-5884 Wax esters biosynthesis I 9 LLUN010659-PA;LLUN007057-PA;LLUN007115-PA;LLUN004653-PA;LLUN011511-PA;LLUN008939-PA;LLUN012272-PA;LLUN002150-PA;LLUN003549-PA KEGG: 00900+3.4.24.84 Terpenoid backbone biosynthesis 1 LLUN008099-PA KEGG: 05170+2.7.1.153 Human immunodeficiency virus 1 infection 1 LLUN006224-PA KEGG: 00710+5.1.3.1 Carbon fixation in photosynthetic organisms 2 LLUN010698-PA;LLUN010699-PA Reactome: R-HSA-9637628 Modulation by Mtb of host immune system 1 LLUN005530-PA Reactome: R-HSA-5689880 Ub-specific processing proteases 41 LLUN006627-PA;LLUN009980-PA;LLUN008342-PA;LLUN006525-PA;LLUN013272-PA;LLUN005030-PA;LLUN003629-PA;LLUN005593-PA;LLUN004508-PA;LLUN005530-PA;LLUN006442-PA;LLUN002894-PA;LLUN009994-PA;LLUN004861-PA;LLUN012461-PA;LLUN006267-PA;LLUN008863-PA;LLUN002054-PA;LLUN002998-PA;LLUN012063-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN008960-PA;LLUN012548-PA;LLUN003971-PA;LLUN003501-PA;LLUN005440-PA;LLUN012004-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN008306-PA;LLUN008477-PA;LLUN005610-PA;LLUN002409-PA;LLUN004794-PA;LLUN005061-PA;LLUN005258-PA;LLUN002753-PA;LLUN000089-PA MetaCyc: PWY-1281 Sulfoacetaldehyde degradation I 2 LLUN007189-PA;LLUN000223-PA Reactome: R-HSA-2980766 Nuclear Envelope Breakdown 1 LLUN011507-PA Reactome: R-HSA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 12 LLUN007762-PA;LLUN011636-PA;LLUN009061-PA;LLUN000042-PA;LLUN011947-PA;LLUN003653-PA;LLUN000527-PA;LLUN002437-PA;LLUN006579-PA;LLUN000041-PA;LLUN008157-PA;LLUN009201-PA Reactome: R-HSA-1855204 Synthesis of IP3 and IP4 in the cytosol 4 LLUN008499-PA;LLUN009162-PA;LLUN004409-PA;LLUN007371-PA Reactome: R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 9 LLUN006404-PA;LLUN011753-PA;LLUN011540-PA;LLUN001769-PA;LLUN012461-PA;LLUN009715-PA;LLUN003217-PA;LLUN005530-PA;LLUN006637-PA Reactome: R-HSA-389661 Glyoxylate metabolism and glycine degradation 20 LLUN007701-PA;LLUN000030-PA;LLUN006625-PA;LLUN005718-PA;LLUN009509-PA;LLUN008836-PA;LLUN000029-PA;LLUN000900-PA;LLUN001342-PA;LLUN008574-PA;LLUN012256-PA;LLUN005170-PA;LLUN010662-PA;LLUN000031-PA;LLUN003848-PA;LLUN010459-PA;LLUN003018-PA;LLUN008148-PA;LLUN008350-PA;LLUN009954-PA MetaCyc: PWY-7176 UTP and CTP de novo biosynthesis 7 LLUN000315-PA;LLUN006247-PA;LLUN006609-PA;LLUN012527-PA;LLUN011985-PA;LLUN012628-PA;LLUN000213-PA Reactome: R-HSA-3232142 SUMOylation of ubiquitinylation proteins 10 LLUN004789-PA;LLUN001776-PA;LLUN003438-PA;LLUN008894-PA;LLUN010831-PA;LLUN012529-PA;LLUN008374-PA;LLUN013269-PA;LLUN001860-PA;LLUN007599-PA MetaCyc: PWY-5538 Pyruvate fermentation to acetate VI 7 LLUN012993-PA;LLUN007878-PA;LLUN003300-PA;LLUN008350-PA;LLUN007880-PA;LLUN007879-PA;LLUN011264-PA KEGG: 00072+2.3.3.10 Synthesis and degradation of ketone bodies 1 LLUN007815-PA KEGG: 00053+1.13.99.1 Ascorbate and aldarate metabolism 1 LLUN004918-PA MetaCyc: PWY-4361 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I 7 LLUN000197-PA;LLUN003319-PA;LLUN000196-PA;LLUN009193-PA;LLUN012415-PA;LLUN011488-PA;LLUN006114-PA Reactome: R-HSA-5693607 Processing of DNA double-strand break ends 18 LLUN008476-PA;LLUN011570-PA;LLUN012395-PA;LLUN005530-PA;LLUN000692-PA;LLUN000563-PA;LLUN010115-PA;LLUN010205-PA;LLUN003498-PA;LLUN011433-PA;LLUN012819-PA;LLUN007180-PA;LLUN010570-PA;LLUN011163-PA;LLUN003560-PA;LLUN011874-PA;LLUN012021-PA;LLUN012973-PA Reactome: R-HSA-912526 Interleukin receptor SHC signaling 1 LLUN006897-PA Reactome: R-HSA-211976 Endogenous sterols 1 LLUN006656-PA MetaCyc: PWY-5826 Hypoglycin biosynthesis 3 LLUN000741-PA;LLUN000193-PA;LLUN001088-PA Reactome: R-HSA-68949 Orc1 removal from chromatin 42 LLUN005265-PA;LLUN005530-PA;LLUN002894-PA;LLUN013272-PA;LLUN008245-PA;LLUN005030-PA;LLUN003629-PA;LLUN007051-PA;LLUN005593-PA;LLUN004508-PA;LLUN004644-PA;LLUN006525-PA;LLUN007960-PA;LLUN006627-PA;LLUN008160-PA;LLUN009980-PA;LLUN004645-PA;LLUN008342-PA;LLUN008485-PA;LLUN000089-PA;LLUN003215-PA;LLUN004706-PA;LLUN010012-PA;LLUN008477-PA;LLUN008146-PA;LLUN005610-PA;LLUN004794-PA;LLUN008960-PA;LLUN004578-PA;LLUN012548-PA;LLUN003501-PA;LLUN008154-PA;LLUN005440-PA;LLUN004861-PA;LLUN009994-PA;LLUN006111-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA MetaCyc: PWY-1881 Formate oxidation to CO2 1 LLUN009876-PA Reactome: R-HSA-69481 G2/M Checkpoints 30 LLUN009994-PA;LLUN006627-PA;LLUN004861-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN008342-PA;LLUN008960-PA;LLUN012548-PA;LLUN005440-PA;LLUN003501-PA;LLUN006525-PA;LLUN010012-PA;LLUN003215-PA;LLUN005030-PA;LLUN004706-PA;LLUN013272-PA;LLUN003629-PA;LLUN008477-PA;LLUN005610-PA;LLUN005593-PA;LLUN004794-PA;LLUN004508-PA;LLUN005530-PA;LLUN000089-PA;LLUN002894-PA Reactome: R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 2 LLUN009676-PA;LLUN005309-PA MetaCyc: PWY-5138 Fatty acid beta-oxidation IV (unsaturated, even number) 4 LLUN007706-PA;LLUN000586-PA;LLUN008953-PA;LLUN011561-PA MetaCyc: PWY-6587 Pyruvate fermentation to ethanol III 1 LLUN012888-PA Reactome: R-HSA-3928663 EPHA-mediated growth cone collapse 1 LLUN012841-PA KEGG: 00062+2.3.1.199 Fatty acid elongation 16 LLUN000999-PA;LLUN011712-PA;LLUN002535-PA;LLUN003915-PA;LLUN003366-PA;LLUN004697-PA;LLUN004698-PA;LLUN001587-PA;LLUN008915-PA;LLUN011428-PA;LLUN002534-PA;LLUN003202-PA;LLUN001586-PA;LLUN001585-PA;LLUN005813-PA;LLUN003913-PA KEGG: 00620+6.2.1.1 Pyruvate metabolism 2 LLUN001912-PA;LLUN000254-PA KEGG: 00790+3.5.4.16 Folate biosynthesis 2 LLUN012034-PA;LLUN005541-PA Reactome: R-HSA-69091 Polymerase switching 8 LLUN008719-PA;LLUN012973-PA;LLUN001634-PA;LLUN006991-PA;LLUN009996-PA;LLUN004948-PA;LLUN010178-PA;LLUN011570-PA Reactome: R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 1 LLUN011378-PA Reactome: R-HSA-4755609 Defective DHDDS causes retinitis pigmentosa 59 2 LLUN000175-PA;LLUN012075-PA Reactome: R-HSA-196757 Metabolism of folate and pterines 12 LLUN000777-PA;LLUN000274-PA;LLUN011200-PA;LLUN010882-PA;LLUN011129-PA;LLUN000209-PA;LLUN000040-PA;LLUN005962-PA;LLUN000042-PA;LLUN006558-PA;LLUN010048-PA;LLUN000542-PA KEGG: 00590+3.1.1.4 Arachidonic acid metabolism 7 LLUN008242-PA;LLUN003919-PA;LLUN003536-PA;LLUN001370-PA;LLUN001410-PA;LLUN008580-PA;LLUN000563-PA Reactome: R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 1 LLUN005530-PA KEGG: 00970+2.1.2.9 Aminoacyl-tRNA biosynthesis 5 LLUN008884-PA;LLUN000772-PA;LLUN000691-PA;LLUN006932-PA;LLUN008431-PA KEGG: 00500+2.4.1.25 Starch and sucrose metabolism 3 LLUN010451-PA;LLUN004023-PA;LLUN000671-PA Reactome: R-HSA-916853 Degradation of GABA 1 LLUN003809-PA KEGG: 00020+1.2.4.1 Citrate cycle (TCA cycle) 1 LLUN000032-PA KEGG: 00270+2.6.1.1 Cysteine and methionine metabolism 1 LLUN009219-PA MetaCyc: PWY-5384 Sucrose degradation IV (sucrose phosphorylase) 1 LLUN000137-PA KEGG: 00062+4.2.1.134 Fatty acid elongation 2 LLUN011810-PA;LLUN009068-PA MetaCyc: PWY-7779 Methyl tert-butyl ether degradation 4 LLUN011561-PA;LLUN007706-PA;LLUN000586-PA;LLUN008953-PA Reactome: R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 11 LLUN004553-PA;LLUN011652-PA;LLUN002905-PA;LLUN010388-PA;LLUN013251-PA;LLUN010206-PA;LLUN001888-PA;LLUN008475-PA;LLUN013198-PA;LLUN001889-PA;LLUN012629-PA Reactome: R-HSA-165158 Activation of AKT2 1 LLUN007485-PA KEGG: 00450+2.1.1.13 Selenocompound metabolism 1 LLUN000141-PA KEGG: 00232+1.7.3.3 Caffeine metabolism 1 LLUN007804-PA Reactome: R-HSA-1237112 Methionine salvage pathway 3 LLUN000197-PA;LLUN000196-PA;LLUN003319-PA Reactome: R-HSA-5205685 Pink/Parkin Mediated Mitophagy 5 LLUN001578-PA;LLUN011108-PA;LLUN005530-PA;LLUN008662-PA;LLUN011856-PA KEGG: 00540+2.3.1.242 Lipopolysaccharide biosynthesis 1 LLUN000116-PA Reactome: R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 70 LLUN005594-PA;LLUN012076-PA;LLUN006093-PA;LLUN000493-PA;LLUN007100-PA;LLUN004402-PA;LLUN000856-PA;LLUN004621-PA;LLUN012053-PA;LLUN008680-PA;LLUN007972-PA;LLUN001675-PA;LLUN008597-PA;LLUN003999-PA;LLUN008152-PA;LLUN010350-PA;LLUN003033-PA;LLUN006098-PA;LLUN003515-PA;LLUN003497-PA;LLUN005084-PA;LLUN003524-PA;LLUN012390-PA;LLUN005586-PA;LLUN007812-PA;LLUN004193-PA;LLUN011199-PA;LLUN004513-PA;LLUN010052-PA;LLUN000494-PA;LLUN005442-PA;LLUN012611-PA;LLUN002390-PA;LLUN003780-PA;LLUN002560-PA;LLUN008530-PA;LLUN006512-PA;LLUN008357-PA;LLUN012474-PA;LLUN002787-PA;LLUN005308-PA;LLUN004837-PA;LLUN011304-PA;LLUN001670-PA;LLUN003373-PA;LLUN006863-PA;LLUN001948-PA;LLUN006279-PA;LLUN001569-PA;LLUN004682-PA;LLUN003745-PA;LLUN009177-PA;LLUN009419-PA;LLUN007733-PA;LLUN011174-PA;LLUN010153-PA;LLUN002287-PA;LLUN007661-PA;LLUN012495-PA;LLUN004909-PA;LLUN010136-PA;LLUN000340-PA;LLUN008995-PA;LLUN007563-PA;LLUN012333-PA;LLUN010358-PA;LLUN009774-PA;LLUN009998-PA;LLUN007425-PA;LLUN005530-PA Reactome: R-HSA-1295596 Spry regulation of FGF signaling 2 LLUN002516-PA;LLUN005530-PA Reactome: R-HSA-167290 Pausing and recovery of HIV elongation 16 LLUN000521-PA;LLUN007798-PA;LLUN001676-PA;LLUN009178-PA;LLUN003321-PA;LLUN001290-PA;LLUN001654-PA;LLUN009747-PA;LLUN011861-PA;LLUN011586-PA;LLUN009648-PA;LLUN008120-PA;LLUN009871-PA;LLUN002218-PA;LLUN011260-PA;LLUN007911-PA KEGG: 00627+3.6.1.7 Aminobenzoate degradation 2 LLUN003978-PA;LLUN004267-PA KEGG: 00521+5.5.1.4 Streptomycin biosynthesis 1 LLUN006316-PA Reactome: R-HSA-5632684 Hedgehog 'on' state 34 LLUN002894-PA;LLUN005530-PA;LLUN005593-PA;LLUN004508-PA;LLUN005656-PA;LLUN013272-PA;LLUN005030-PA;LLUN003629-PA;LLUN001628-PA;LLUN006525-PA;LLUN008342-PA;LLUN006627-PA;LLUN009980-PA;LLUN000089-PA;LLUN005610-PA;LLUN004794-PA;LLUN011978-PA;LLUN010012-PA;LLUN003215-PA;LLUN004706-PA;LLUN008477-PA;LLUN003501-PA;LLUN005440-PA;LLUN010850-PA;LLUN008960-PA;LLUN012548-PA;LLUN002998-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN009994-PA;LLUN004861-PA;LLUN006267-PA;LLUN002054-PA KEGG: 00250+2.1.3.2 Alanine, aspartate and glutamate metabolism 1 LLUN000087-PA Reactome: R-HSA-3928665 EPH-ephrin mediated repulsion of cells 7 LLUN003449-PA;LLUN011753-PA;LLUN011540-PA;LLUN007104-PA;LLUN000410-PA;LLUN001957-PA;LLUN003412-PA Reactome: R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 2 LLUN009996-PA;LLUN004016-PA Reactome: R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 9 LLUN011570-PA;LLUN008476-PA;LLUN005530-PA;LLUN007180-PA;LLUN009996-PA;LLUN006941-PA;LLUN001634-PA;LLUN012973-PA;LLUN008719-PA Reactome: R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 1 LLUN005530-PA Reactome: R-HSA-8939247 RUNX1 regulates transcription of genes involved in interleukin signaling 3 LLUN009497-PA;LLUN009496-PA;LLUN009498-PA KEGG: 00642+2.3.1.16 Ethylbenzene degradation 1 LLUN000585-PA Reactome: R-HSA-5689603 UCH proteinases 38 LLUN002547-PA;LLUN005530-PA;LLUN002894-PA;LLUN008663-PA;LLUN006654-PA;LLUN003629-PA;LLUN013272-PA;LLUN003864-PA;LLUN005030-PA;LLUN004508-PA;LLUN005593-PA;LLUN006525-PA;LLUN009980-PA;LLUN006627-PA;LLUN008342-PA;LLUN005258-PA;LLUN000089-PA;LLUN008477-PA;LLUN012308-PA;LLUN003215-PA;LLUN004706-PA;LLUN010012-PA;LLUN004794-PA;LLUN005610-PA;LLUN013219-PA;LLUN012548-PA;LLUN008960-PA;LLUN003501-PA;LLUN005440-PA;LLUN000599-PA;LLUN002054-PA;LLUN006267-PA;LLUN004861-PA;LLUN009994-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN002998-PA Reactome: R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 5 LLUN009646-PA;LLUN002886-PA;LLUN004942-PA;LLUN004092-PA;LLUN013127-PA KEGG: 00010+4.1.2.13 Glycolysis / Gluconeogenesis 3 LLUN000832-PA;LLUN000906-PA;LLUN011949-PA Reactome: R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 1 LLUN011378-PA Reactome: R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 8 LLUN009442-PA;LLUN009496-PA;LLUN009497-PA;LLUN005309-PA;LLUN009498-PA;LLUN007292-PA;LLUN011224-PA;LLUN012904-PA KEGG: 00760+2.3.1.286 Nicotinate and nicotinamide metabolism 8 LLUN005073-PA;LLUN011139-PA;LLUN004580-PA;LLUN004427-PA;LLUN006019-PA;LLUN008490-PA;LLUN008936-PA;LLUN009387-PA MetaCyc: PWY-6981 Chitin biosynthesis 1 LLUN000137-PA MetaCyc: PWY-7115 C4 photosynthetic carbon assimilation cycle, NAD-ME type 9 LLUN005628-PA;LLUN009219-PA;LLUN012438-PA;LLUN000543-PA;LLUN006407-PA;LLUN000276-PA;LLUN008095-PA;LLUN009867-PA;LLUN008096-PA Reactome: R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 7 LLUN000848-PA;LLUN004685-PA;LLUN007882-PA;LLUN004076-PA;LLUN012097-PA;LLUN000845-PA;LLUN012273-PA MetaCyc: PWY-6608 Guanosine nucleotides degradation III 3 LLUN000578-PA;LLUN000322-PA;LLUN009431-PA KEGG: 00130+4.1.1.98 Ubiquinone and other terpenoid-quinone biosynthesis 1 LLUN000584-PA Reactome: R-HSA-5633231 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) 2 LLUN000041-PA;LLUN002437-PA KEGG: 00260+1.4.4.2 Glycine, serine and threonine metabolism 2 LLUN010254-PA;LLUN000899-PA Reactome: R-HSA-381038 XBP1(S) activates chaperone genes 5 LLUN008641-PA;LLUN011046-PA;LLUN010802-PA;LLUN005954-PA;LLUN001691-PA KEGG: 00471+5.1.1.3 D-Glutamine and D-glutamate metabolism 2 LLUN000191-PA;LLUN000549-PA Reactome: R-HSA-9027276 Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 1 LLUN006224-PA MetaCyc: PWY-5082 L-methionine degradation III 1 LLUN012888-PA KEGG: 05163+2.7.1.153 Human cytomegalovirus infection 1 LLUN006224-PA MetaCyc: PWY-6958 Icosapentaenoate biosynthesis I (lower eukaryotes) 2 LLUN011810-PA;LLUN009068-PA Reactome: R-HSA-72731 Recycling of eIF2:GDP 1 LLUN011183-PA Reactome: R-HSA-170660 Adenylate cyclase activating pathway 2 LLUN004610-PA;LLUN004430-PA Reactome: R-HSA-4655427 SUMOylation of DNA methylation proteins 2 LLUN001605-PA;LLUN007122-PA MetaCyc: PWY-6309 L-tryptophan degradation XI (mammalian, via kynurenine) 1 LLUN004035-PA KEGG: 00230+2.4.2.8 Purine metabolism 1 LLUN006332-PA KEGG: 00720+1.3.5.4 Carbon fixation pathways in prokaryotes 1 LLUN000261-PA Reactome: R-HSA-9665244 Resistance of ERBB2 KD mutants to sapitinib 2 LLUN008416-PA;LLUN008205-PA Reactome: R-HSA-209560 NF-kB is activated and signals survival 1 LLUN005530-PA KEGG: 00660+6.2.1.5 C5-Branched dibasic acid metabolism 7 LLUN012993-PA;LLUN007880-PA;LLUN007879-PA;LLUN011264-PA;LLUN003300-PA;LLUN007878-PA;LLUN008350-PA KEGG: 00900+2.5.1.58 Terpenoid backbone biosynthesis 1 LLUN008320-PA Reactome: R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 6 LLUN011192-PA;LLUN012849-PA;LLUN006440-PA;LLUN005189-PA;LLUN004283-PA;LLUN007485-PA KEGG: 00970+6.1.1.15 Aminoacyl-tRNA biosynthesis 1 LLUN007623-PA Reactome: R-HSA-5696394 DNA Damage Recognition in GG-NER 7 LLUN012308-PA;LLUN005995-PA;LLUN005530-PA;LLUN011775-PA;LLUN006404-PA;LLUN008663-PA;LLUN001769-PA KEGG: 00330+2.5.1.16 Arginine and proline metabolism 2 LLUN006330-PA;LLUN010439-PA MetaCyc: PWY-7524 Mevalonate pathway III (archaea) 3 LLUN006160-PA;LLUN007815-PA;LLUN006161-PA KEGG: 00260+4.3.1.17 Glycine, serine and threonine metabolism 2 LLUN000073-PA;LLUN009374-PA Reactome: R-HSA-5694530 Cargo concentration in the ER 3 LLUN009459-PA;LLUN007816-PA;LLUN011749-PA MetaCyc: PWY-7801 N-end rule pathway I (prokaryotic) 1 LLUN012002-PA Reactome: R-HSA-180910 Vpr-mediated nuclear import of PICs 10 LLUN007599-PA;LLUN001860-PA;LLUN013269-PA;LLUN008374-PA;LLUN008894-PA;LLUN010831-PA;LLUN012529-PA;LLUN001776-PA;LLUN003438-PA;LLUN004789-PA Reactome: R-HSA-8951936 RUNX3 regulates p14-ARF 3 LLUN009498-PA;LLUN009496-PA;LLUN009497-PA Reactome: R-HSA-201681 TCF dependent signaling in response to WNT 2 LLUN010265-PA;LLUN005530-PA Reactome: R-HSA-1855167 Synthesis of pyrophosphates in the cytosol 2 LLUN006346-PA;LLUN009162-PA MetaCyc: PWY-6863 Pyruvate fermentation to hexanol (engineered) 5 LLUN000585-PA;LLUN007706-PA;LLUN000586-PA;LLUN008953-PA;LLUN011561-PA MetaCyc: PWY-6834 Spermidine biosynthesis III 3 LLUN010564-PA;LLUN006330-PA;LLUN001283-PA KEGG: 00550+6.3.2.9 Peptidoglycan biosynthesis 1 LLUN000042-PA KEGG: 00983+2.4.2.8 Drug metabolism - other enzymes 1 LLUN006332-PA MetaCyc: PWY-5703 Urea degradation I 1 LLUN001217-PA KEGG: 00270+4.1.1.50 Cysteine and methionine metabolism 3 LLUN001283-PA;LLUN010564-PA;LLUN006330-PA Reactome: R-HSA-425986 Sodium/Proton exchangers 3 LLUN011206-PA;LLUN013253-PA;LLUN007720-PA KEGG: 00550+6.3.2.8 Peptidoglycan biosynthesis 1 LLUN000040-PA KEGG: 00600+3.2.1.45 Sphingolipid metabolism 1 LLUN001270-PA MetaCyc: PWY-5695 Inosine 5'-phosphate degradation 5 LLUN000578-PA;LLUN000322-PA;LLUN000036-PA;LLUN009431-PA;LLUN008234-PA Reactome: R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 2 LLUN002516-PA;LLUN011839-PA Reactome: R-HSA-399719 Trafficking of AMPA receptors 3 LLUN011839-PA;LLUN006792-PA;LLUN007814-PA Reactome: R-HSA-8949275 RUNX3 Regulates Immune Response and Cell Migration 3 LLUN009498-PA;LLUN009496-PA;LLUN009497-PA Reactome: R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 1 LLUN003047-PA Reactome: R-HSA-3371571 HSF1-dependent transactivation 4 LLUN006440-PA;LLUN005189-PA;LLUN011839-PA;LLUN012849-PA MetaCyc: PWY-7854 Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered) 2 LLUN007673-PA;LLUN000144-PA KEGG: 00062+4.2.1.17+1.1.1.35 Fatty acid elongation 4 LLUN007706-PA;LLUN008953-PA;LLUN000586-PA;LLUN011561-PA KEGG: 00270+2.1.1.13 Cysteine and methionine metabolism 1 LLUN000141-PA MetaCyc: PWY-7291 Oleate beta-oxidation (isomerase-dependent, yeast) 1 LLUN000586-PA KEGG: 00130+4.1.1.90 Ubiquinone and other terpenoid-quinone biosynthesis 1 LLUN009130-PA KEGG: 00860+4.99.1.1 Porphyrin and chlorophyll metabolism 1 LLUN000765-PA Reactome: R-HSA-191859 snRNP Assembly 16 LLUN003218-PA;LLUN005901-PA;LLUN005558-PA;LLUN009131-PA;LLUN001776-PA;LLUN013269-PA;LLUN008894-PA;LLUN012529-PA;LLUN010831-PA;LLUN001860-PA;LLUN007599-PA;LLUN003438-PA;LLUN004789-PA;LLUN008374-PA;LLUN000235-PA;LLUN002884-PA Reactome: R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 3 LLUN010444-PA;LLUN002369-PA;LLUN008644-PA KEGG: 00730+3.6.1.15 Thiamine metabolism 1 LLUN003082-PA MetaCyc: PWY-5653 NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde 1 LLUN000035-PA Reactome: R-HSA-5637810 Constitutive Signaling by EGFRvIII 2 LLUN008205-PA;LLUN008416-PA Reactome: R-HSA-947581 Molybdenum cofactor biosynthesis 3 LLUN000056-PA;LLUN010509-PA;LLUN011579-PA Reactome: R-HSA-418597 G alpha (z) signalling events 2 LLUN004610-PA;LLUN004430-PA KEGG: 00670+2.1.2.9 One carbon pool by folate 5 LLUN006932-PA;LLUN008431-PA;LLUN000691-PA;LLUN000772-PA;LLUN008884-PA Reactome: R-HSA-111463 SMAC (DIABLO) binds to IAPs 7 LLUN003801-PA;LLUN006836-PA;LLUN003543-PA;LLUN011140-PA;LLUN011888-PA;LLUN001057-PA;LLUN006174-PA Reactome: R-HSA-8935964 RUNX1 regulates expression of components of tight junctions 3 LLUN009496-PA;LLUN009497-PA;LLUN009498-PA KEGG: 00230+6.3.4.13 Purine metabolism 3 LLUN006933-PA;LLUN006932-PA;LLUN010077-PA MetaCyc: PWY-4661 1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza) 2 LLUN009162-PA;LLUN006316-PA Reactome: R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 8 LLUN000286-PA;LLUN001285-PA;LLUN006957-PA;LLUN001734-PA;LLUN005975-PA;LLUN004817-PA;LLUN009365-PA;LLUN002499-PA Reactome: R-HSA-3785653 Myoclonic epilepsy of Lafora 1 LLUN005530-PA Reactome: R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 1 LLUN011839-PA MetaCyc: PWY-6370 Ascorbate recycling (cytosolic) 2 LLUN008086-PA;LLUN008487-PA Reactome: R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 20 LLUN005922-PA;LLUN007599-PA;LLUN012671-PA;LLUN003100-PA;LLUN001860-PA;LLUN003350-PA;LLUN008374-PA;LLUN003133-PA;LLUN003438-PA;LLUN004789-PA;LLUN009131-PA;LLUN006672-PA;LLUN002473-PA;LLUN011623-PA;LLUN013269-PA;LLUN012529-PA;LLUN008894-PA;LLUN010831-PA;LLUN001776-PA;LLUN012727-PA Reactome: R-HSA-5654706 FRS-mediated FGFR3 signaling 1 LLUN002128-PA Reactome: R-HSA-180746 Nuclear import of Rev protein 11 LLUN001860-PA;LLUN007599-PA;LLUN008699-PA;LLUN004789-PA;LLUN001776-PA;LLUN003438-PA;LLUN008894-PA;LLUN010831-PA;LLUN012529-PA;LLUN013269-PA;LLUN008374-PA Reactome: R-HSA-6809371 Formation of the cornified envelope 6 LLUN007908-PA;LLUN006999-PA;LLUN007718-PA;LLUN007907-PA;LLUN005543-PA;LLUN010975-PA MetaCyc: PWY-7315 Dtdp-n-acetylthomosamine biosynthesis 1 LLUN000559-PA Reactome: R-HSA-73817 Purine ribonucleoside monophosphate biosynthesis 14 LLUN010078-PA;LLUN002619-PA;LLUN000215-PA;LLUN006932-PA;LLUN010077-PA;LLUN004569-PA;LLUN002429-PA;LLUN009293-PA;LLUN006933-PA;LLUN000036-PA;LLUN008234-PA;LLUN000266-PA;LLUN000772-PA;LLUN008637-PA KEGG: 00790+2.5.1.15 Folate biosynthesis 1 LLUN000281-PA MetaCyc: PWY-7226 Guanosine deoxyribonucleotides de novo biosynthesis I 7 LLUN006247-PA;LLUN012527-PA;LLUN001080-PA;LLUN011985-PA;LLUN008193-PA;LLUN012628-PA;LLUN000213-PA Reactome: R-HSA-5654732 Negative regulation of FGFR3 signaling 2 LLUN002516-PA;LLUN005530-PA MetaCyc: PWY-6519 8-amino-7-oxononanoate biosynthesis I 4 LLUN003811-PA;LLUN000176-PA;LLUN000184-PA;LLUN005169-PA KEGG: 00190+7.1.2.2 Oxidative phosphorylation 5 LLUN005731-PA;LLUN000558-PA;LLUN001187-PA;LLUN006324-PA;LLUN002012-PA KEGG: 00270+4.4.1.13 Cysteine and methionine metabolism 1 LLUN000310-PA Reactome: R-HSA-446210 Synthesis of UDP-N-acetyl-glucosamine 2 LLUN001655-PA;LLUN001189-PA Reactome: R-HSA-388844 Receptor-type tyrosine-protein phosphatases 1 LLUN011055-PA KEGG: 00790+3.4.19.9 Folate biosynthesis 2 LLUN001010-PA;LLUN006148-PA KEGG: 00620+1.1.1.37 Pyruvate metabolism 3 LLUN000276-PA;LLUN009867-PA;LLUN012438-PA MetaCyc: PWY-5751 Phenylethanol biosynthesis 1 LLUN012888-PA Reactome: R-HSA-8939902 Regulation of RUNX2 expression and activity 35 LLUN006525-PA;LLUN009497-PA;LLUN008342-PA;LLUN006627-PA;LLUN009980-PA;LLUN002894-PA;LLUN005530-PA;LLUN009498-PA;LLUN005593-PA;LLUN004508-PA;LLUN005030-PA;LLUN013272-PA;LLUN003629-PA;LLUN005440-PA;LLUN003501-PA;LLUN008960-PA;LLUN012548-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN006111-PA;LLUN009994-PA;LLUN004861-PA;LLUN006267-PA;LLUN002054-PA;LLUN000089-PA;LLUN005610-PA;LLUN009496-PA;LLUN004794-PA;LLUN010012-PA;LLUN003215-PA;LLUN004706-PA;LLUN006158-PA;LLUN008477-PA KEGG: 00450+6.1.1.10 Selenocompound metabolism 1 LLUN010671-PA KEGG: 00250+2.6.1.16 Alanine, aspartate and glutamate metabolism 2 LLUN001189-PA;LLUN001655-PA KEGG: 00983+2.4.2.3 Drug metabolism - other enzymes 1 LLUN000578-PA Reactome: R-HSA-9656255 Defective OGG1 Substrate Binding 1 LLUN005053-PA KEGG: 00630+2.1.2.1 Glyoxylate and dicarboxylate metabolism 3 LLUN011129-PA;LLUN000209-PA;LLUN006558-PA KEGG: 00030+4.1.2.13 Pentose phosphate pathway 3 LLUN000906-PA;LLUN011949-PA;LLUN000832-PA KEGG: 04070+3.1.3.25 Phosphatidylinositol signaling system 2 LLUN003712-PA;LLUN000211-PA KEGG: 00520+3.2.1.14 Amino sugar and nucleotide sugar metabolism 9 LLUN007726-PA;LLUN005932-PA;LLUN005795-PA;LLUN000048-PA;LLUN006418-PA;LLUN009014-PA;LLUN007221-PA;LLUN001719-PA;LLUN004333-PA KEGG: 00620+2.7.2.1 Pyruvate metabolism 2 LLUN009622-PA;LLUN007189-PA MetaCyc: PWY-5265 Peptidoglycan biosynthesis II (staphylococci) 7 LLUN011710-PA;LLUN000042-PA;LLUN011947-PA;LLUN000207-PA;LLUN002437-PA;LLUN000674-PA;LLUN000041-PA KEGG: 00564+2.3.1.51 Glycerophospholipid metabolism 2 LLUN008689-PA;LLUN000308-PA Reactome: R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 30 LLUN005530-PA;LLUN000089-PA;LLUN002894-PA;LLUN003215-PA;LLUN005030-PA;LLUN010012-PA;LLUN004706-PA;LLUN013272-PA;LLUN008477-PA;LLUN003629-PA;LLUN005610-PA;LLUN005593-PA;LLUN004794-PA;LLUN004508-PA;LLUN008960-PA;LLUN012548-PA;LLUN005440-PA;LLUN003501-PA;LLUN006525-PA;LLUN004861-PA;LLUN009994-PA;LLUN006627-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN008342-PA MetaCyc: PWY-5675 Nitrate reduction V (assimilatory) 4 LLUN000515-PA;LLUN002676-PA;LLUN000514-PA;LLUN002238-PA KEGG: 00511+3.2.1.45 Other glycan degradation 1 LLUN001270-PA MetaCyc: PWY-6558 Heparan sulfate biosynthesis (late stages) 3 LLUN012994-PA;LLUN001417-PA;LLUN008728-PA KEGG: 00970+6.1.1.18 Aminoacyl-tRNA biosynthesis 2 LLUN005993-PA;LLUN007278-PA Reactome: R-HSA-1483255 PI Metabolism 1 LLUN009029-PA Reactome: R-HSA-379716 Cytosolic tRNA aminoacylation 17 LLUN010296-PA;LLUN008398-PA;LLUN010162-PA;LLUN005993-PA;LLUN000083-PA;LLUN011446-PA;LLUN000150-PA;LLUN001890-PA;LLUN007746-PA;LLUN012421-PA;LLUN011099-PA;LLUN000332-PA;LLUN010324-PA;LLUN007278-PA;LLUN007624-PA;LLUN009127-PA;LLUN012491-PA Reactome: R-HSA-1250196 SHC1 events in ERBB2 signaling 1 LLUN000021-PA MetaCyc: PWY-5739 GDP-D-perosamine biosynthesis 1 LLUN000234-PA Reactome: R-HSA-156590 Glutathione conjugation 4 LLUN000130-PA;LLUN008487-PA;LLUN008086-PA;LLUN006555-PA Reactome: R-HSA-8873719 RAB geranylgeranylation 4 LLUN005823-PA;LLUN000357-PA;LLUN011181-PA;LLUN007852-PA Reactome: R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 20 LLUN002707-PA;LLUN001322-PA;LLUN008923-PA;LLUN008763-PA;LLUN006723-PA;LLUN003240-PA;LLUN001652-PA;LLUN011046-PA;LLUN009062-PA;LLUN011766-PA;LLUN004100-PA;LLUN003553-PA;LLUN000039-PA;LLUN006353-PA;LLUN011179-PA;LLUN003554-PA;LLUN007825-PA;LLUN002581-PA;LLUN003209-PA;LLUN009963-PA Reactome: R-HSA-176412 Phosphorylation of the APC/C 7 LLUN012097-PA;LLUN007882-PA;LLUN004076-PA;LLUN004685-PA;LLUN000848-PA;LLUN012273-PA;LLUN000845-PA Reactome: R-HSA-9648025 EML4 and NUDC in mitotic spindle formation 23 LLUN009963-PA;LLUN003209-PA;LLUN002581-PA;LLUN004221-PA;LLUN007825-PA;LLUN003554-PA;LLUN011378-PA;LLUN011179-PA;LLUN006353-PA;LLUN000039-PA;LLUN003553-PA;LLUN004100-PA;LLUN003438-PA;LLUN011766-PA;LLUN009062-PA;LLUN009748-PA;LLUN002475-PA;LLUN003240-PA;LLUN006723-PA;LLUN008923-PA;LLUN010831-PA;LLUN001322-PA;LLUN002707-PA Reactome: R-HSA-2564830 Cytosolic iron-sulfur cluster assembly 4 LLUN000404-PA;LLUN012274-PA;LLUN005333-PA;LLUN008353-PA Reactome: R-HSA-5620916 VxPx cargo-targeting to cilium 5 LLUN012444-PA;LLUN007564-PA;LLUN003747-PA;LLUN002928-PA;LLUN011106-PA MetaCyc: PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis 3 LLUN008499-PA;LLUN007371-PA;LLUN004409-PA Reactome: R-HSA-3214858 RMTs methylate histone arginines 10 LLUN008610-PA;LLUN004016-PA;LLUN006200-PA;LLUN012482-PA;LLUN011913-PA;LLUN003218-PA;LLUN002257-PA;LLUN005901-PA;LLUN010120-PA;LLUN002900-PA KEGG: 00720+6.4.1.2 Carbon fixation pathways in prokaryotes 2 LLUN011458-PA;LLUN005463-PA Reactome: R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 2 LLUN006897-PA;LLUN000021-PA KEGG: 00360+4.2.1.17 Phenylalanine metabolism 4 LLUN011561-PA;LLUN007706-PA;LLUN000586-PA;LLUN008953-PA Reactome: R-HSA-877312 Regulation of IFNG signaling 1 LLUN000806-PA MetaCyc: PWY-7936 Psilocybin biosynthesis 17 LLUN004808-PA;LLUN009043-PA;LLUN007962-PA;LLUN007396-PA;LLUN007963-PA;LLUN006054-PA;LLUN012499-PA;LLUN006423-PA;LLUN009665-PA;LLUN010575-PA;LLUN008033-PA;LLUN006421-PA;LLUN006422-PA;LLUN007629-PA;LLUN003206-PA;LLUN000568-PA;LLUN012747-PA Reactome: R-HSA-9629232 Defective Base Excision Repair Associated with NEIL3 1 LLUN000526-PA Reactome: R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 4 LLUN011378-PA;LLUN000021-PA;LLUN006897-PA;LLUN002516-PA MetaCyc: PWY-6151 S-adenosyl-L-methionine cycle I 2 LLUN000578-PA;LLUN004715-PA KEGG: 05235+3.1.3.16 PD-L1 expression and PD-1 checkpoint pathway in cancer 18 LLUN009434-PA;LLUN009226-PA;LLUN006059-PA;LLUN002541-PA;LLUN000352-PA;LLUN008672-PA;LLUN012288-PA;LLUN007568-PA;LLUN005608-PA;LLUN008489-PA;LLUN002952-PA;LLUN010631-PA;LLUN003214-PA;LLUN013018-PA;LLUN004286-PA;LLUN007414-PA;LLUN002955-PA;LLUN007006-PA Reactome: R-HSA-2132295 MHC class II antigen presentation 48 LLUN006286-PA;LLUN006594-PA;LLUN009963-PA;LLUN003903-PA;LLUN002031-PA;LLUN007825-PA;LLUN012673-PA;LLUN000039-PA;LLUN006593-PA;LLUN007885-PA;LLUN011179-PA;LLUN003553-PA;LLUN004942-PA;LLUN011204-PA;LLUN004100-PA;LLUN011766-PA;LLUN011046-PA;LLUN009646-PA;LLUN001652-PA;LLUN011749-PA;LLUN004924-PA;LLUN007528-PA;LLUN011746-PA;LLUN003240-PA;LLUN008923-PA;LLUN005824-PA;LLUN008763-PA;LLUN004944-PA;LLUN001322-PA;LLUN009021-PA;LLUN002707-PA;LLUN003209-PA;LLUN002581-PA;LLUN008804-PA;LLUN003904-PA;LLUN001084-PA;LLUN006288-PA;LLUN003554-PA;LLUN005178-PA;LLUN001775-PA;LLUN006353-PA;LLUN009062-PA;LLUN013279-PA;LLUN008848-PA;LLUN006287-PA;LLUN007871-PA;LLUN006723-PA;LLUN012575-PA Reactome: R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 16 LLUN011586-PA;LLUN009648-PA;LLUN008120-PA;LLUN002218-PA;LLUN009871-PA;LLUN011260-PA;LLUN007911-PA;LLUN000521-PA;LLUN007798-PA;LLUN001676-PA;LLUN009178-PA;LLUN003321-PA;LLUN001290-PA;LLUN001654-PA;LLUN009747-PA;LLUN011861-PA MetaCyc: PWY-5941 Glycogen degradation II 7 LLUN000671-PA;LLUN010451-PA;LLUN001762-PA;LLUN009874-PA;LLUN004023-PA;LLUN000667-PA;LLUN000295-PA Reactome: R-HSA-6804757 Regulation of TP53 Degradation 6 LLUN005530-PA;LLUN007485-PA;LLUN012849-PA;LLUN011192-PA;LLUN004283-PA;LLUN006440-PA Reactome: R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 7 LLUN012273-PA;LLUN000845-PA;LLUN012097-PA;LLUN004076-PA;LLUN007882-PA;LLUN004685-PA;LLUN000848-PA MetaCyc: PWY-4984 Urea cycle 6 LLUN008409-PA;LLUN000151-PA;LLUN000086-PA;LLUN002360-PA;LLUN000546-PA;LLUN000085-PA Reactome: R-HSA-8964616 G beta:gamma signalling through CDC42 1 LLUN006122-PA Reactome: R-HSA-111469 SMAC, XIAP-regulated apoptotic response 1 LLUN001057-PA Reactome: R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 2 LLUN012461-PA;LLUN005530-PA KEGG: 00930+4.2.1.17+1.1.1.35 Caprolactam degradation 4 LLUN011561-PA;LLUN008953-PA;LLUN000586-PA;LLUN007706-PA MetaCyc: PWY-7292 Oleate beta-oxidation (thioesterase-dependent, yeast) 1 LLUN000586-PA KEGG: 00230+3.6.1.9 Purine metabolism 3 LLUN003890-PA;LLUN006214-PA;LLUN000110-PA Reactome: R-HSA-1169408 ISG15 antiviral mechanism 16 LLUN000443-PA;LLUN000554-PA;LLUN003438-PA;LLUN013168-PA;LLUN004789-PA;LLUN008374-PA;LLUN005530-PA;LLUN001860-PA;LLUN007599-PA;LLUN001776-PA;LLUN012608-PA;LLUN013269-PA;LLUN008894-PA;LLUN012529-PA;LLUN010831-PA;LLUN005674-PA KEGG: 00040+5.1.3.22 Pentose and glucuronate interconversions 1 LLUN000670-PA Reactome: R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 1 LLUN004972-PA MetaCyc: PWY-7717 3-hydroxy-4-methyl-anthranilate biosynthesis I 1 LLUN004035-PA KEGG: 00730+2.7.4.3 Thiamine metabolism 3 LLUN008895-PA;LLUN006609-PA;LLUN000764-PA Reactome: R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 3 LLUN008644-PA;LLUN010444-PA;LLUN011732-PA Reactome: R-HSA-68867 Assembly of the pre-replicative complex 11 LLUN004578-PA;LLUN004644-PA;LLUN005265-PA;LLUN008485-PA;LLUN008154-PA;LLUN007960-PA;LLUN008160-PA;LLUN008245-PA;LLUN004645-PA;LLUN008146-PA;LLUN007051-PA Reactome: R-HSA-5685942 HDR through Homologous Recombination (HRR) 20 LLUN006020-PA;LLUN000692-PA;LLUN005530-PA;LLUN008476-PA;LLUN011570-PA;LLUN009996-PA;LLUN000563-PA;LLUN010205-PA;LLUN003498-PA;LLUN011433-PA;LLUN011403-PA;LLUN012819-PA;LLUN008719-PA;LLUN007180-PA;LLUN011163-PA;LLUN000062-PA;LLUN002154-PA;LLUN012760-PA;LLUN012973-PA;LLUN001634-PA Reactome: R-HSA-163765 ChREBP activates metabolic gene expression 13 LLUN003046-PA;LLUN005809-PA;LLUN011458-PA;LLUN005276-PA;LLUN009379-PA;LLUN000495-PA;LLUN012922-PA;LLUN005277-PA;LLUN009575-PA;LLUN009868-PA;LLUN007878-PA;LLUN000497-PA;LLUN005463-PA KEGG: 00680+2.3.1.8 Methane metabolism 2 LLUN000223-PA;LLUN007189-PA MetaCyc: PWY-5381 Pyridine nucleotide cycling (plants) 5 LLUN000322-PA;LLUN000035-PA;LLUN012146-PA;LLUN010074-PA;LLUN009089-PA Reactome: R-HSA-5423646 Aflatoxin activation and detoxification 8 LLUN004711-PA;LLUN000005-PA;LLUN005398-PA;LLUN013118-PA;LLUN003868-PA;LLUN007499-PA;LLUN000428-PA;LLUN010503-PA Reactome: R-HSA-202733 Cell surface interactions at the vascular wall 2 LLUN004191-PA;LLUN004949-PA KEGG: 00513+2.4.1.258 Various types of N-glycan biosynthesis 1 LLUN003653-PA KEGG: 00230+1.17.1.4 Purine metabolism 1 LLUN009431-PA KEGG: 00620+4.1.1.32 Pyruvate metabolism 1 LLUN003283-PA KEGG: 00240+1.3.5.2 Pyrimidine metabolism 2 LLUN008467-PA;LLUN013209-PA Reactome: R-HSA-163210 Formation of ATP by chemiosmotic coupling 10 LLUN001867-PA;LLUN009889-PA;LLUN013185-PA;LLUN011510-PA;LLUN004166-PA;LLUN008259-PA;LLUN009056-PA;LLUN001186-PA;LLUN001187-PA;LLUN008019-PA MetaCyc: PWY-7094 Fatty acid salvage 5 LLUN011561-PA;LLUN000586-PA;LLUN008953-PA;LLUN000585-PA;LLUN007706-PA Reactome: R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 12 LLUN004789-PA;LLUN003438-PA;LLUN009748-PA;LLUN001776-PA;LLUN008894-PA;LLUN012529-PA;LLUN010831-PA;LLUN008374-PA;LLUN013269-PA;LLUN001860-PA;LLUN007599-PA;LLUN008699-PA MetaCyc: PWY-8025 Cyanuric acid degradation I 1 LLUN000192-PA KEGG: 00290+2.3.3.13 Valine, leucine and isoleucine biosynthesis 1 LLUN000046-PA Reactome: R-HSA-2206292 MPS VII - Sly syndrome 2 LLUN010751-PA;LLUN000905-PA Reactome: R-HSA-1222556 ROS and RNS production in phagocytes 14 LLUN002284-PA;LLUN005643-PA;LLUN005731-PA;LLUN005072-PA;LLUN010285-PA;LLUN004638-PA;LLUN002241-PA;LLUN004088-PA;LLUN002836-PA;LLUN012843-PA;LLUN004087-PA;LLUN002685-PA;LLUN012577-PA;LLUN012460-PA Reactome: R-HSA-354192 Integrin signaling 1 LLUN007485-PA KEGG: 00603+3.2.1.22 Glycosphingolipid biosynthesis - globo and isoglobo series 4 LLUN007044-PA;LLUN005205-PA;LLUN010776-PA;LLUN001202-PA KEGG: 00983+2.4.2.4 Drug metabolism - other enzymes 1 LLUN000064-PA Reactome: R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 31 LLUN008342-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN002998-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA;LLUN004861-PA;LLUN009994-PA;LLUN006627-PA;LLUN006111-PA;LLUN006525-PA;LLUN003501-PA;LLUN005440-PA;LLUN012548-PA;LLUN008960-PA;LLUN004508-PA;LLUN004794-PA;LLUN005593-PA;LLUN005610-PA;LLUN003629-PA;LLUN008477-PA;LLUN013272-PA;LLUN004706-PA;LLUN003215-PA;LLUN005030-PA;LLUN010012-PA;LLUN002894-PA;LLUN000089-PA;LLUN005530-PA MetaCyc: PWY-5340 Sulfate activation for sulfonation 1 LLUN000320-PA MetaCyc: PWY-7838 Globo-series glycosphingolipids biosynthesis 1 LLUN004238-PA KEGG: 00030+3.1.3.11 Pentose phosphate pathway 2 LLUN008377-PA;LLUN000273-PA KEGG: 00521+2.7.1.1 Streptomycin biosynthesis 2 LLUN005483-PA;LLUN003849-PA Reactome: R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 1 LLUN012841-PA MetaCyc: PWY-5132 Lupulone and humulone biosynthesis 2 LLUN001912-PA;LLUN000254-PA Reactome: R-HSA-3214842 HDMs demethylate histones 6 LLUN005252-PA;LLUN003839-PA;LLUN005878-PA;LLUN011481-PA;LLUN004135-PA;LLUN006013-PA KEGG: 00480+6.3.2.3 Glutathione metabolism 4 LLUN008974-PA;LLUN012049-PA;LLUN008975-PA;LLUN000913-PA Reactome: R-HSA-186797 Signaling by PDGF 2 LLUN004092-PA;LLUN004475-PA KEGG: 00380+1.8.1.4 Tryptophan metabolism 1 LLUN000029-PA Reactome: R-HSA-9029558 NR1H2 & NR1H3 regulate gene expression linked to lipogenesis 10 LLUN000495-PA;LLUN003046-PA;LLUN005276-PA;LLUN005809-PA;LLUN009379-PA;LLUN012922-PA;LLUN005277-PA;LLUN009575-PA;LLUN009868-PA;LLUN000497-PA Reactome: R-HSA-5676590 NIK-->noncanonical NF-kB signaling 32 LLUN008960-PA;LLUN012548-PA;LLUN003501-PA;LLUN005440-PA;LLUN004861-PA;LLUN009994-PA;LLUN010119-PA;LLUN006111-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN000089-PA;LLUN010012-PA;LLUN003215-PA;LLUN004706-PA;LLUN008477-PA;LLUN005610-PA;LLUN004794-PA;LLUN006525-PA;LLUN006627-PA;LLUN009980-PA;LLUN008342-PA;LLUN005530-PA;LLUN002894-PA;LLUN013272-PA;LLUN005030-PA;LLUN003629-PA;LLUN005593-PA;LLUN004508-PA Reactome: R-HSA-9613829 Chaperone Mediated Autophagy 3 LLUN012758-PA;LLUN000749-PA;LLUN005530-PA MetaCyc: PWY-5891 Menaquinol-11 biosynthesis 2 LLUN000579-PA;LLUN007379-PA MetaCyc: PWY-6983 Threo-tetrahydrobiopterin biosynthesis 3 LLUN005541-PA;LLUN010032-PA;LLUN012034-PA MetaCyc: PWY-2722 Trehalose degradation IV 1 LLUN009874-PA Reactome: R-HSA-8874081 MET activates PTK2 signaling 6 LLUN000595-PA;LLUN013127-PA;LLUN000590-PA;LLUN000591-PA;LLUN000003-PA;LLUN001511-PA Reactome: R-HSA-4719360 Defective DPM3 causes DPM3-CDG (CDG-1o) 1 LLUN006904-PA Reactome: R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 46 LLUN009994-PA;LLUN004861-PA;LLUN008923-PA;LLUN002054-PA;LLUN006267-PA;LLUN001322-PA;LLUN002998-PA;LLUN002707-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN008960-PA;LLUN012548-PA;LLUN003501-PA;LLUN005440-PA;LLUN003240-PA;LLUN011179-PA;LLUN004706-PA;LLUN003215-PA;LLUN000039-PA;LLUN010012-PA;LLUN003553-PA;LLUN011766-PA;LLUN004100-PA;LLUN008477-PA;LLUN005610-PA;LLUN004794-PA;LLUN007825-PA;LLUN000089-PA;LLUN006723-PA;LLUN006627-PA;LLUN009980-PA;LLUN008342-PA;LLUN006525-PA;LLUN006353-PA;LLUN013272-PA;LLUN005030-PA;LLUN009062-PA;LLUN003629-PA;LLUN005593-PA;LLUN004508-PA;LLUN002581-PA;LLUN003209-PA;LLUN005530-PA;LLUN003554-PA;LLUN002894-PA MetaCyc: PWY-5669 Phosphatidylserine and phosphatidylethanolamine biosynthesis I 4 LLUN010169-PA;LLUN000568-PA;LLUN000263-PA;LLUN002860-PA MetaCyc: PWY-7077 N-acetyl-D-galactosamine degradation 1 LLUN000895-PA KEGG: 00592+3.1.1.4 alpha-Linolenic acid metabolism 6 LLUN003536-PA;LLUN001370-PA;LLUN003919-PA;LLUN008242-PA;LLUN008580-PA;LLUN001410-PA KEGG: 00061+6.4.1.2 Fatty acid biosynthesis 2 LLUN005463-PA;LLUN011458-PA KEGG: 00770+2.2.1.6 Pantothenate and CoA biosynthesis 2 LLUN000551-PA;LLUN000044-PA Reactome: R-HSA-429947 Deadenylation of mRNA 3 LLUN011726-PA;LLUN008959-PA;LLUN005459-PA Reactome: R-HSA-5657562 Essential fructosuria 1 LLUN001623-PA MetaCyc: PWY-6961 L-ascorbate degradation II (bacterial, aerobic) 1 LLUN000670-PA MetaCyc: PWY-6146 Methanobacterium thermoautotrophicum biosynthetic metabolism 1 LLUN000543-PA Reactome: R-HSA-1912399 Pre-NOTCH Processing in the Endoplasmic Reticulum 1 LLUN003131-PA Reactome: R-HSA-164378 PKA activation in glucagon signalling 2 LLUN004430-PA;LLUN004610-PA Reactome: R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 25 LLUN008091-PA;LLUN009871-PA;LLUN002218-PA;LLUN008120-PA;LLUN009648-PA;LLUN011586-PA;LLUN001301-PA;LLUN012654-PA;LLUN010602-PA;LLUN007911-PA;LLUN011260-PA;LLUN001565-PA;LLUN010911-PA;LLUN009178-PA;LLUN001676-PA;LLUN007798-PA;LLUN008353-PA;LLUN000521-PA;LLUN011861-PA;LLUN009747-PA;LLUN001654-PA;LLUN002995-PA;LLUN002096-PA;LLUN001290-PA;LLUN003321-PA Reactome: R-HSA-196025 Formation of annular gap junctions 2 LLUN011540-PA;LLUN011753-PA Reactome: R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 31 LLUN001948-PA;LLUN001569-PA;LLUN003999-PA;LLUN002560-PA;LLUN004682-PA;LLUN006512-PA;LLUN003033-PA;LLUN003745-PA;LLUN009177-PA;LLUN002287-PA;LLUN006098-PA;LLUN008357-PA;LLUN007425-PA;LLUN005530-PA;LLUN005308-PA;LLUN012076-PA;LLUN007812-PA;LLUN007100-PA;LLUN004402-PA;LLUN004621-PA;LLUN000856-PA;LLUN000340-PA;LLUN012053-PA;LLUN008680-PA;LLUN011199-PA;LLUN004513-PA;LLUN001670-PA;LLUN003373-PA;LLUN006863-PA;LLUN007563-PA;LLUN012611-PA MetaCyc: PWY-2821 Glucosinolate biosynthesis from phenylalanine 1 LLUN000310-PA Reactome: R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 11 LLUN012494-PA;LLUN009254-PA;LLUN005642-PA;LLUN001957-PA;LLUN000389-PA;LLUN003844-PA;LLUN011975-PA;LLUN009680-PA;LLUN005530-PA;LLUN007104-PA;LLUN003449-PA MetaCyc: PWY-581 Indole-3-acetate biosynthesis II 1 LLUN000568-PA Reactome: R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 23 LLUN007911-PA;LLUN001565-PA;LLUN011260-PA;LLUN008120-PA;LLUN002218-PA;LLUN009871-PA;LLUN011586-PA;LLUN009648-PA;LLUN010602-PA;LLUN012654-PA;LLUN001301-PA;LLUN011861-PA;LLUN002995-PA;LLUN001654-PA;LLUN009747-PA;LLUN001290-PA;LLUN003321-PA;LLUN009178-PA;LLUN010911-PA;LLUN001676-PA;LLUN007798-PA;LLUN008353-PA;LLUN000521-PA MetaCyc: PWY-3722 Glycine betaine biosynthesis II (Gram-positive bacteria) 4 LLUN010781-PA;LLUN012260-PA;LLUN008188-PA;LLUN011634-PA Reactome: R-HSA-162710 Synthesis of glycosylphosphatidylinositol (GPI) 5 LLUN008452-PA;LLUN008451-PA;LLUN007791-PA;LLUN001169-PA;LLUN003730-PA Reactome: R-HSA-165159 mTOR signalling 6 LLUN006440-PA;LLUN005189-PA;LLUN005447-PA;LLUN005085-PA;LLUN012849-PA;LLUN006176-PA MetaCyc: PWY-7586 Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation 2 LLUN011806-PA;LLUN007218-PA KEGG: 00400+2.6.1.1 Phenylalanine, tyrosine and tryptophan biosynthesis 1 LLUN009219-PA KEGG: 00860+4.2.1.24 Porphyrin and chlorophyll metabolism 2 LLUN011442-PA;LLUN010957-PA MetaCyc: PWY-5188 Tetrapyrrole biosynthesis I (from glutamate) 5 LLUN011442-PA;LLUN000232-PA;LLUN000561-PA;LLUN009306-PA;LLUN010957-PA Reactome: R-HSA-9603798 Class I peroxisomal membrane protein import 4 LLUN012682-PA;LLUN000250-PA;LLUN011430-PA;LLUN007085-PA Reactome: R-HSA-174430 Telomere C-strand synthesis initiation 3 LLUN006991-PA;LLUN004948-PA;LLUN010178-PA Reactome: R-HSA-4717374 Defective DPM1 causes DPM1-CDG (CDG-1e) 1 LLUN006904-PA Reactome: R-HSA-3270619 IRF3-mediated induction of type I IFN 2 LLUN004049-PA;LLUN010205-PA Reactome: R-HSA-3560801 Defective B3GAT3 causes JDSSDHD 2 LLUN002060-PA;LLUN004191-PA Reactome: R-HSA-5362798 Release of Hh-Np from the secreting cell 4 LLUN005656-PA;LLUN010850-PA;LLUN003870-PA;LLUN001628-PA MetaCyc: PWY-5484 Glycolysis II (from fructose 6-phosphate) 19 LLUN011949-PA;LLUN010011-PA;LLUN008377-PA;LLUN000534-PA;LLUN012863-PA;LLUN002938-PA;LLUN002937-PA;LLUN000535-PA;LLUN008352-PA;LLUN010054-PA;LLUN007408-PA;LLUN000906-PA;LLUN000530-PA;LLUN000907-PA;LLUN012182-PA;LLUN000832-PA;LLUN013179-PA;LLUN009807-PA;LLUN000273-PA KEGG: 00073+1.2.1.84 Cutin, suberine and wax biosynthesis 9 LLUN003549-PA;LLUN002150-PA;LLUN004653-PA;LLUN011511-PA;LLUN007057-PA;LLUN007115-PA;LLUN010659-PA;LLUN012272-PA;LLUN008939-PA MetaCyc: PWY-7206 Pyrimidine deoxyribonucleotides dephosphorylation 3 LLUN000110-PA;LLUN003890-PA;LLUN006214-PA Reactome: R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 1 LLUN002516-PA Reactome: R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 1 LLUN005530-PA Reactome: R-HSA-4551295 Defective ALG11 causes ALG11-CDG (CDG-1p) 1 LLUN009061-PA KEGG: 00970+6.3.5.7 Aminoacyl-tRNA biosynthesis 8 LLUN001218-PA;LLUN007551-PA;LLUN004242-PA;LLUN008301-PA;LLUN000192-PA;LLUN004241-PA;LLUN011681-PA;LLUN001759-PA MetaCyc: PWY-7800 Ac/N-end rule pathway 5 LLUN007836-PA;LLUN002815-PA;LLUN010557-PA;LLUN000170-PA;LLUN008126-PA KEGG: 00564+2.7.1.107 Glycerophospholipid metabolism 3 LLUN000135-PA;LLUN001142-PA;LLUN012411-PA Reactome: R-HSA-418457 cGMP effects 1 LLUN000812-PA Reactome: R-HSA-1482798 Acyl chain remodeling of CL 1 LLUN012321-PA MetaCyc: PWY-7855 Ectoine degradation 1 LLUN008772-PA KEGG: 00260+1.2.1.8+1.1.99.1 Glycine, serine and threonine metabolism 4 LLUN011634-PA;LLUN008188-PA;LLUN010781-PA;LLUN012260-PA Reactome: R-HSA-190861 Gap junction assembly 16 LLUN006723-PA;LLUN008923-PA;LLUN002707-PA;LLUN001322-PA;LLUN003240-PA;LLUN009062-PA;LLUN011766-PA;LLUN004100-PA;LLUN003553-PA;LLUN011179-PA;LLUN006353-PA;LLUN000039-PA;LLUN002581-PA;LLUN003209-PA;LLUN003554-PA;LLUN007825-PA MetaCyc: PWY-5367 Petroselinate biosynthesis 2 LLUN000184-PA;LLUN005169-PA Reactome: R-HSA-4420332 Defective B3GALT6 causes EDSP2 and SEMDJL1 2 LLUN002060-PA;LLUN004191-PA KEGG: 00680+4.1.1.31 Methane metabolism 1 LLUN000543-PA Reactome: R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 5 LLUN011465-PA;LLUN006087-PA;LLUN011466-PA;LLUN001691-PA;LLUN003870-PA MetaCyc: PWY-6893 Thiamine diphosphate biosynthesis II (Bacillus) 1 LLUN000288-PA KEGG: 00362+4.2.1.17+1.1.1.35 Benzoate degradation 4 LLUN011561-PA;LLUN007706-PA;LLUN008953-PA;LLUN000586-PA KEGG: 00260+4.2.1.20 Glycine, serine and threonine metabolism 1 LLUN012017-PA MetaCyc: PWY-5392 Reductive TCA cycle II 14 LLUN009867-PA;LLUN000276-PA;LLUN007880-PA;LLUN003300-PA;LLUN008350-PA;LLUN012993-PA;LLUN012634-PA;LLUN012438-PA;LLUN000261-PA;LLUN007879-PA;LLUN011264-PA;LLUN007878-PA;LLUN005021-PA;LLUN000255-PA KEGG: 00250+6.3.4.4 Alanine, aspartate and glutamate metabolism 1 LLUN000266-PA MetaCyc: PWY-6471 Peptidoglycan biosynthesis IV (Enterococcus faecium) 7 LLUN011947-PA;LLUN011710-PA;LLUN000042-PA;LLUN000041-PA;LLUN000207-PA;LLUN002437-PA;LLUN000674-PA KEGG: 00983+2.7.4.14 Drug metabolism - other enzymes 1 LLUN006609-PA Reactome: R-HSA-1368082 RORA activates gene expression 5 LLUN004016-PA;LLUN008644-PA;LLUN010444-PA;LLUN005720-PA;LLUN012442-PA Reactome: R-HSA-2142789 Ubiquinol biosynthesis 7 LLUN010266-PA;LLUN000901-PA;LLUN000579-PA;LLUN013052-PA;LLUN000136-PA;LLUN003684-PA;LLUN007379-PA MetaCyc: PWY-7942 5-oxo-L-proline metabolism 7 LLUN005267-PA;LLUN006865-PA;LLUN005397-PA;LLUN005396-PA;LLUN005986-PA;LLUN004190-PA;LLUN000941-PA Reactome: R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 3 LLUN011749-PA;LLUN008164-PA;LLUN008699-PA KEGG: 00513+2.4.1.131 Various types of N-glycan biosynthesis 1 LLUN009061-PA Reactome: R-HSA-8878166 Transcriptional regulation by RUNX2 3 LLUN009496-PA;LLUN009497-PA;LLUN009498-PA Reactome: R-HSA-168276 NS1 Mediated Effects on Host Pathways 13 LLUN005674-PA;LLUN007599-PA;LLUN001860-PA;LLUN013269-PA;LLUN008374-PA;LLUN010831-PA;LLUN008894-PA;LLUN012529-PA;LLUN001776-PA;LLUN003438-PA;LLUN012608-PA;LLUN004789-PA;LLUN013168-PA Reactome: R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 4 LLUN010205-PA;LLUN012395-PA;LLUN010761-PA;LLUN004049-PA MetaCyc: PWY-6886 1-butanol autotrophic biosynthesis (engineered) 6 LLUN000530-PA;LLUN010011-PA;LLUN013179-PA;LLUN007408-PA;LLUN000907-PA;LLUN012182-PA Reactome: R-HSA-445095 Interaction between L1 and Ankyrins 4 LLUN010289-PA;LLUN010550-PA;LLUN007877-PA;LLUN010548-PA MetaCyc: PWY-5084 2-oxoglutarate decarboxylation to succinyl-CoA 2 LLUN008349-PA;LLUN000029-PA MetaCyc: PWY-6637 Sulfolactate degradation II 2 LLUN000223-PA;LLUN007189-PA KEGG: 00510+2.4.1.131 N-Glycan biosynthesis 1 LLUN009061-PA Reactome: R-HSA-2514859 Inactivation, recovery and regulation of the phototransduction cascade 5 LLUN012473-PA;LLUN010557-PA;LLUN002815-PA;LLUN008320-PA;LLUN008126-PA Reactome: R-HSA-202424 Downstream TCR signaling 32 LLUN008342-PA;LLUN009980-PA;LLUN006627-PA;LLUN006525-PA;LLUN004508-PA;LLUN005593-PA;LLUN003629-PA;LLUN013272-PA;LLUN005030-PA;LLUN002894-PA;LLUN005530-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN002998-PA;LLUN002054-PA;LLUN006267-PA;LLUN004861-PA;LLUN009994-PA;LLUN006111-PA;LLUN003501-PA;LLUN005440-PA;LLUN012548-PA;LLUN008960-PA;LLUN007485-PA;LLUN004794-PA;LLUN005610-PA;LLUN008477-PA;LLUN003215-PA;LLUN004706-PA;LLUN010012-PA;LLUN000089-PA KEGG: 00260+1.8.1.4 Glycine, serine and threonine metabolism 1 LLUN000029-PA KEGG: 00051+2.7.1.11 Fructose and mannose metabolism 3 LLUN000534-PA;LLUN002937-PA;LLUN002938-PA Reactome: R-HSA-73780 RNA Polymerase III Chain Elongation 12 LLUN007985-PA;LLUN001676-PA;LLUN009871-PA;LLUN011849-PA;LLUN005850-PA;LLUN001167-PA;LLUN007829-PA;LLUN000521-PA;LLUN006359-PA;LLUN007911-PA;LLUN001290-PA;LLUN003293-PA MetaCyc: PWY-6502 8-oxo-(d)GTP detoxification I 2 LLUN003437-PA;LLUN000038-PA Reactome: R-HSA-5358493 Synthesis of diphthamide-EEF2 4 LLUN008287-PA;LLUN009500-PA;LLUN000091-PA;LLUN002119-PA Reactome: R-HSA-5578999 Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) 2 LLUN007915-PA;LLUN009565-PA MetaCyc: PWY-6609 Adenine and adenosine salvage III 3 LLUN004537-PA;LLUN006332-PA;LLUN000578-PA Reactome: R-HSA-400511 Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) 3 LLUN009969-PA;LLUN005822-PA;LLUN001397-PA Reactome: R-HSA-176974 Unwinding of DNA 11 LLUN008083-PA;LLUN008889-PA;LLUN008154-PA;LLUN005265-PA;LLUN004578-PA;LLUN004496-PA;LLUN007051-PA;LLUN008146-PA;LLUN004913-PA;LLUN008160-PA;LLUN009477-PA KEGG: 00230+6.3.5.2 Purine metabolism 3 LLUN009293-PA;LLUN000215-PA;LLUN002619-PA MetaCyc: PWY-8041 Ultra-long-chain fatty acid biosynthesis 18 LLUN003915-PA;LLUN004698-PA;LLUN003366-PA;LLUN004697-PA;LLUN002535-PA;LLUN000999-PA;LLUN011712-PA;LLUN003913-PA;LLUN011810-PA;LLUN005813-PA;LLUN003202-PA;LLUN001586-PA;LLUN009068-PA;LLUN001585-PA;LLUN001587-PA;LLUN008915-PA;LLUN011428-PA;LLUN002534-PA KEGG: 00052+5.1.3.3 Galactose metabolism 2 LLUN005832-PA;LLUN001157-PA Reactome: R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 1 LLUN011378-PA KEGG: 00790+3.1.3.1 Folate biosynthesis 12 LLUN008172-PA;LLUN002237-PA;LLUN006397-PA;LLUN008359-PA;LLUN011373-PA;LLUN002910-PA;LLUN012626-PA;LLUN008360-PA;LLUN006398-PA;LLUN006396-PA;LLUN006399-PA;LLUN005387-PA Reactome: R-HSA-1433557 Signaling by SCF-KIT 1 LLUN006897-PA KEGG: 00983+3.5.4.5 Drug metabolism - other enzymes 1 LLUN012848-PA Reactome: R-HSA-1227986 Signaling by ERBB2 3 LLUN000021-PA;LLUN008416-PA;LLUN008205-PA Reactome: R-HSA-5654733 Negative regulation of FGFR4 signaling 2 LLUN005530-PA;LLUN002516-PA Reactome: R-HSA-5099900 WNT5A-dependent internalization of FZD4 1 LLUN011753-PA MetaCyc: PWY-5651 L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde 1 LLUN004035-PA Reactome: R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex 9 LLUN010444-PA;LLUN011978-PA;LLUN008644-PA;LLUN011466-PA;LLUN004269-PA;LLUN011465-PA;LLUN002616-PA;LLUN004270-PA;LLUN006125-PA KEGG: 00250+6.3.4.5 Alanine, aspartate and glutamate metabolism 2 LLUN008409-PA;LLUN000151-PA MetaCyc: PWY-7569 Arginomycin biosynthesis 1 LLUN000166-PA Reactome: R-HSA-450341 Activation of the AP-1 family of transcription factors 2 LLUN007704-PA;LLUN002516-PA Reactome: R-HSA-166208 mTORC1-mediated signalling 7 LLUN012849-PA;LLUN005085-PA;LLUN006440-PA;LLUN005447-PA;LLUN005189-PA;LLUN007812-PA;LLUN006176-PA MetaCyc: PWY-6163 Chorismate biosynthesis from 3-dehydroquinate 3 LLUN012009-PA;LLUN011560-PA;LLUN000675-PA Reactome: R-HSA-9656256 Defective OGG1 Substrate Processing 1 LLUN005053-PA Reactome: R-HSA-388841 Costimulation by the CD28 family 1 LLUN006897-PA MetaCyc: PWY-7831 ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide 1 LLUN012521-PA MetaCyc: PWY-7570 Blasticidin S biosynthesis 1 LLUN000166-PA Reactome: R-HSA-6802953 RAS signaling downstream of NF1 loss-of-function variants 1 LLUN008842-PA MetaCyc: PWY-2301 Myo-inositol biosynthesis 3 LLUN006316-PA;LLUN000211-PA;LLUN003712-PA Reactome: R-HSA-8953750 Transcriptional Regulation by E2F6 2 LLUN007434-PA;LLUN005292-PA MetaCyc: PWY-4983 Nitric oxide biosynthesis II (mammals) 4 LLUN008409-PA;LLUN000151-PA;LLUN002360-PA;LLUN000546-PA Reactome: R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 18 LLUN008353-PA;LLUN007798-PA;LLUN000521-PA;LLUN009178-PA;LLUN010911-PA;LLUN001676-PA;LLUN001290-PA;LLUN011861-PA;LLUN001654-PA;LLUN002995-PA;LLUN010602-PA;LLUN012654-PA;LLUN001301-PA;LLUN010082-PA;LLUN009871-PA;LLUN001565-PA;LLUN007911-PA;LLUN004511-PA MetaCyc: PWY-7858 (5Z)-dodecenoate biosynthesis II 4 LLUN003811-PA;LLUN000176-PA;LLUN000184-PA;LLUN005169-PA KEGG: 00680+2.7.1.11 Methane metabolism 3 LLUN000534-PA;LLUN002937-PA;LLUN002938-PA MetaCyc: PWY-7409 Phospholipid remodeling (phosphatidylethanolamine, yeast) 7 LLUN001410-PA;LLUN008580-PA;LLUN000563-PA;LLUN003919-PA;LLUN008242-PA;LLUN003536-PA;LLUN001370-PA KEGG: 00680+5.4.2.11 Methane metabolism 2 LLUN010054-PA;LLUN008352-PA KEGG: 00630+1.11.1.6 Glyoxylate and dicarboxylate metabolism 4 LLUN001796-PA;LLUN002757-PA;LLUN008395-PA;LLUN000578-PA KEGG: 00380+1.2.4.2 Tryptophan metabolism 1 LLUN008349-PA Reactome: R-HSA-165181 Inhibition of TSC complex formation by PKB 1 LLUN009495-PA KEGG: 00480+1.17.4.1 Glutathione metabolism 2 LLUN001080-PA;LLUN008193-PA MetaCyc: PWY-6606 Guanosine nucleotides degradation II 2 LLUN009431-PA;LLUN000322-PA Reactome: R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 3 LLUN010205-PA;LLUN005530-PA;LLUN012395-PA MetaCyc: PWY-8004 Entner-Doudoroff pathway I 9 LLUN000907-PA;LLUN012182-PA;LLUN004963-PA;LLUN009154-PA;LLUN010011-PA;LLUN008352-PA;LLUN010054-PA;LLUN007408-PA;LLUN013179-PA KEGG: 00531+3.2.1.52 Glycosaminoglycan degradation 6 LLUN010383-PA;LLUN007975-PA;LLUN008090-PA;LLUN003183-PA;LLUN007651-PA;LLUN009341-PA KEGG: 00500+2.7.1.2 Starch and sucrose metabolism 1 LLUN009874-PA MetaCyc: PWY-2221 Entner-Doudoroff pathway III (semi-phosphorylative) 4 LLUN000530-PA;LLUN013179-PA;LLUN007408-PA;LLUN012182-PA Reactome: R-HSA-212436 Generic Transcription Pathway 16 LLUN006049-PA;LLUN000492-PA;LLUN010569-PA;LLUN005720-PA;LLUN003325-PA;LLUN000459-PA;LLUN008616-PA;LLUN002027-PA;LLUN008795-PA;LLUN001639-PA;LLUN011675-PA;LLUN001235-PA;LLUN006050-PA;LLUN006665-PA;LLUN009192-PA;LLUN001234-PA KEGG: 00010+3.1.3.11 Glycolysis / Gluconeogenesis 2 LLUN000273-PA;LLUN008377-PA Reactome: R-HSA-5674135 MAP2K and MAPK activation 2 LLUN002516-PA;LLUN006176-PA KEGG: 00230+6.3.2.6 Purine metabolism 1 LLUN004569-PA Reactome: R-HSA-174414 Processive synthesis on the C-strand of the telomere 2 LLUN008719-PA;LLUN009996-PA Reactome: R-HSA-8874211 CREB3 factors activate genes 1 LLUN008164-PA KEGG: 00240+4.2.1.70 Pyrimidine metabolism 2 LLUN006156-PA;LLUN012354-PA Reactome: R-HSA-5368286 Mitochondrial translation initiation 40 LLUN009134-PA;LLUN012749-PA;LLUN011356-PA;LLUN010900-PA;LLUN005651-PA;LLUN010361-PA;LLUN000268-PA;LLUN002315-PA;LLUN010333-PA;LLUN009752-PA;LLUN008500-PA;LLUN000171-PA;LLUN003194-PA;LLUN010363-PA;LLUN000285-PA;LLUN005934-PA;LLUN008289-PA;LLUN008596-PA;LLUN000277-PA;LLUN009707-PA;LLUN008084-PA;LLUN004962-PA;LLUN012172-PA;LLUN000540-PA;LLUN000334-PA;LLUN011566-PA;LLUN000761-PA;LLUN000284-PA;LLUN006713-PA;LLUN008128-PA;LLUN008265-PA;LLUN001413-PA;LLUN000269-PA;LLUN007922-PA;LLUN008324-PA;LLUN008073-PA;LLUN012315-PA;LLUN000336-PA;LLUN000691-PA;LLUN006358-PA KEGG: 00630+6.2.1.1 Glyoxylate and dicarboxylate metabolism 2 LLUN000254-PA;LLUN001912-PA Reactome: R-HSA-383280 Nuclear Receptor transcription pathway 34 LLUN004006-PA;LLUN004169-PA;LLUN002396-PA;LLUN001596-PA;LLUN003091-PA;LLUN007223-PA;LLUN000462-PA;LLUN000371-PA;LLUN005860-PA;LLUN004327-PA;LLUN008801-PA;LLUN003984-PA;LLUN008833-PA;LLUN005859-PA;LLUN000878-PA;LLUN005720-PA;LLUN004177-PA;LLUN004005-PA;LLUN003983-PA;LLUN007993-PA;LLUN007994-PA;LLUN005134-PA;LLUN006425-PA;LLUN002895-PA;LLUN001629-PA;LLUN005684-PA;LLUN008468-PA;LLUN008835-PA;LLUN000372-PA;LLUN005234-PA;LLUN005081-PA;LLUN006182-PA;LLUN004328-PA;LLUN006984-PA Reactome: R-HSA-9033807 ABO blood group biosynthesis 1 LLUN012521-PA MetaCyc: PWY-6317 D-galactose degradation I (Leloir pathway) 4 LLUN003916-PA;LLUN001157-PA;LLUN004037-PA;LLUN005832-PA KEGG: 00720+4.2.1.17+1.1.1.35 Carbon fixation pathways in prokaryotes 4 LLUN007706-PA;LLUN008953-PA;LLUN000586-PA;LLUN011561-PA Reactome: R-HSA-110320 Translesion Synthesis by POLH 11 LLUN001634-PA;LLUN012973-PA;LLUN012004-PA;LLUN008130-PA;LLUN011403-PA;LLUN009207-PA;LLUN009996-PA;LLUN011570-PA;LLUN008476-PA;LLUN007180-PA;LLUN005530-PA Reactome: R-HSA-1614517 Sulfide oxidation to sulfate 1 LLUN005831-PA KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8 Fatty acid degradation 1 LLUN000586-PA KEGG: 00790+4.1.99.22 Folate biosynthesis 1 LLUN011579-PA MetaCyc: PWY-7003 Glycerol degradation to butanol 8 LLUN013179-PA;LLUN009807-PA;LLUN000535-PA;LLUN007408-PA;LLUN010011-PA;LLUN000530-PA;LLUN012182-PA;LLUN000907-PA KEGG: 00362+2.3.1.16 Benzoate degradation 1 LLUN000585-PA Reactome: R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 35 LLUN008342-PA;LLUN006627-PA;LLUN009980-PA;LLUN004645-PA;LLUN007960-PA;LLUN006525-PA;LLUN004644-PA;LLUN005593-PA;LLUN004508-PA;LLUN008245-PA;LLUN005030-PA;LLUN013272-PA;LLUN003629-PA;LLUN002894-PA;LLUN005530-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN009994-PA;LLUN004861-PA;LLUN006267-PA;LLUN002054-PA;LLUN005440-PA;LLUN003501-PA;LLUN008960-PA;LLUN012548-PA;LLUN005610-PA;LLUN004794-PA;LLUN003215-PA;LLUN004706-PA;LLUN010012-PA;LLUN008477-PA;LLUN000089-PA;LLUN008485-PA KEGG: 00010+2.7.1.1 Glycolysis / Gluconeogenesis 2 LLUN003849-PA;LLUN005483-PA Reactome: R-HSA-5649702 APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway 3 LLUN006941-PA;LLUN005053-PA;LLUN000181-PA Reactome: R-HSA-5675221 Negative regulation of MAPK pathway 3 LLUN011378-PA;LLUN002516-PA;LLUN005530-PA Reactome: R-HSA-3899300 SUMOylation of transcription cofactors 6 LLUN012758-PA;LLUN008644-PA;LLUN012898-PA;LLUN000749-PA;LLUN011406-PA;LLUN010444-PA MetaCyc: PWY-8073 Lipid IVA biosynthesis (P. putida) 2 LLUN000038-PA;LLUN000177-PA MetaCyc: PWY-6596 Adenosine nucleotides degradation I 4 LLUN000322-PA;LLUN000036-PA;LLUN009431-PA;LLUN008234-PA Reactome: R-HSA-6787450 tRNA modification in the mitochondrion 4 LLUN001194-PA;LLUN000264-PA;LLUN007027-PA;LLUN001873-PA MetaCyc: PWY-5690 TCA cycle II (plants and fungi) 17 LLUN012438-PA;LLUN012634-PA;LLUN012993-PA;LLUN000260-PA;LLUN005021-PA;LLUN000276-PA;LLUN012663-PA;LLUN011041-PA;LLUN003300-PA;LLUN008348-PA;LLUN000255-PA;LLUN007878-PA;LLUN011264-PA;LLUN007879-PA;LLUN009867-PA;LLUN008350-PA;LLUN007880-PA MetaCyc: PWY-7805 (aminomethyl)phosphonate degradation 2 LLUN000272-PA;LLUN003630-PA MetaCyc: PWY-5473 Hydroxycinnamic acid serotonin amides biosynthesis 1 LLUN000568-PA KEGG: 00030+1.1.99.3 Pentose phosphate pathway 1 LLUN003801-PA KEGG: 00970+6.1.1.14 Aminoacyl-tRNA biosynthesis 3 LLUN001205-PA;LLUN011099-PA;LLUN001204-PA Reactome: R-HSA-196299 Beta-catenin phosphorylation cascade 1 LLUN011378-PA KEGG: 00908+2.5.1.75 Zeatin biosynthesis 1 LLUN000264-PA Reactome: R-HSA-111447 Activation of BAD and translocation to mitochondria 1 LLUN002936-PA Reactome: R-HSA-2187335 The retinoid cycle in cones (daylight vision) 1 LLUN009404-PA Reactome: R-HSA-199220 Vitamin B5 (pantothenate) metabolism 11 LLUN000497-PA;LLUN009868-PA;LLUN006777-PA;LLUN009575-PA;LLUN005277-PA;LLUN012922-PA;LLUN005809-PA;LLUN005276-PA;LLUN009379-PA;LLUN003046-PA;LLUN000495-PA Reactome: R-HSA-174490 Membrane binding and targetting of GAG proteins 5 LLUN007046-PA;LLUN005530-PA;LLUN002215-PA;LLUN005247-PA;LLUN013036-PA Reactome: R-HSA-69541 Stabilization of p53 1 LLUN005530-PA Reactome: R-HSA-2467813 Separation of Sister Chromatids 60 LLUN005030-PA;LLUN013272-PA;LLUN006353-PA;LLUN009748-PA;LLUN003629-PA;LLUN009062-PA;LLUN003438-PA;LLUN005593-PA;LLUN004508-PA;LLUN002581-PA;LLUN003209-PA;LLUN005530-PA;LLUN000848-PA;LLUN002894-PA;LLUN011378-PA;LLUN003554-PA;LLUN006723-PA;LLUN006627-PA;LLUN009980-PA;LLUN004685-PA;LLUN012097-PA;LLUN008342-PA;LLUN000845-PA;LLUN002475-PA;LLUN006525-PA;LLUN007882-PA;LLUN004706-PA;LLUN003215-PA;LLUN000039-PA;LLUN010012-PA;LLUN011179-PA;LLUN008477-PA;LLUN011766-PA;LLUN003553-PA;LLUN004100-PA;LLUN005610-PA;LLUN004076-PA;LLUN004794-PA;LLUN004221-PA;LLUN009963-PA;LLUN012273-PA;LLUN007825-PA;LLUN000089-PA;LLUN008923-PA;LLUN009994-PA;LLUN004861-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN001322-PA;LLUN010831-PA;LLUN010393-PA;LLUN011115-PA;LLUN002707-PA;LLUN012429-PA;LLUN008960-PA;LLUN012548-PA;LLUN005440-PA;LLUN003501-PA;LLUN003240-PA Reactome: R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 12 LLUN010831-PA;LLUN008894-PA;LLUN012529-PA;LLUN008374-PA;LLUN006578-PA;LLUN013269-PA;LLUN004789-PA;LLUN001776-PA;LLUN003438-PA;LLUN009131-PA;LLUN007599-PA;LLUN001860-PA KEGG: 00970+6.1.1.10 Aminoacyl-tRNA biosynthesis 1 LLUN010671-PA Reactome: R-HSA-912446 Meiotic recombination 12 LLUN012819-PA;LLUN011433-PA;LLUN002096-PA;LLUN012760-PA;LLUN010205-PA;LLUN006075-PA;LLUN000283-PA;LLUN000692-PA;LLUN007180-PA;LLUN003120-PA;LLUN008476-PA;LLUN006020-PA Reactome: R-HSA-6806664 Metabolism of vitamin K 2 LLUN010143-PA;LLUN001642-PA KEGG: 00620+3.1.2.6 Pyruvate metabolism 2 LLUN000969-PA;LLUN009255-PA MetaCyc: PWY-6902 Chitin degradation II (Vibrio) 15 LLUN007651-PA;LLUN005795-PA;LLUN009341-PA;LLUN003183-PA;LLUN007726-PA;LLUN005932-PA;LLUN007975-PA;LLUN008090-PA;LLUN010383-PA;LLUN000048-PA;LLUN007221-PA;LLUN006418-PA;LLUN009014-PA;LLUN004333-PA;LLUN001719-PA MetaCyc: PWY-7388 Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) 3 LLUN005169-PA;LLUN000184-PA;LLUN000176-PA KEGG: 00620+4.4.1.5 Pyruvate metabolism 1 LLUN012656-PA MetaCyc: PWY-5486 Pyruvate fermentation to ethanol II 1 LLUN012888-PA Reactome: R-HSA-112043 PLC beta mediated events 2 LLUN008499-PA;LLUN004972-PA KEGG: 00480+1.1.1.44 Glutathione metabolism 3 LLUN000245-PA;LLUN006639-PA;LLUN012568-PA KEGG: 00561+2.7.1.107 Glycerolipid metabolism 3 LLUN001142-PA;LLUN000135-PA;LLUN012411-PA Reactome: R-HSA-8939245 RUNX1 regulates transcription of genes involved in BCR signaling 3 LLUN009496-PA;LLUN009497-PA;LLUN009498-PA Reactome: R-HSA-174362 Transport and synthesis of PAPS 1 LLUN000320-PA Reactome: R-HSA-390522 Striated Muscle Contraction 5 LLUN006323-PA;LLUN003597-PA;LLUN003596-PA;LLUN011907-PA;LLUN003496-PA MetaCyc: PWY-7494 Choline degradation IV 4 LLUN011634-PA;LLUN008188-PA;LLUN010781-PA;LLUN012260-PA Reactome: R-HSA-5173105 O-linked glycosylation 3 LLUN008266-PA;LLUN004509-PA;LLUN013133-PA MetaCyc: PWY-5 Canavanine biosynthesis 4 LLUN002360-PA;LLUN000546-PA;LLUN008409-PA;LLUN000151-PA Reactome: R-HSA-70171 Glycolysis 17 LLUN007408-PA;LLUN007276-PA;LLUN000535-PA;LLUN002938-PA;LLUN002937-PA;LLUN000534-PA;LLUN010011-PA;LLUN011949-PA;LLUN003849-PA;LLUN005483-PA;LLUN009807-PA;LLUN013179-PA;LLUN000832-PA;LLUN000137-PA;LLUN012182-PA;LLUN000907-PA;LLUN000908-PA KEGG: 00051+5.3.1.8 Fructose and mannose metabolism 1 LLUN011806-PA KEGG: 00770+4.1.1.36+6.3.2.5 Pantothenate and CoA biosynthesis 1 LLUN000524-PA Reactome: R-HSA-73843 5-Phosphoribose 1-diphosphate biosynthesis 2 LLUN004009-PA;LLUN009897-PA Reactome: R-HSA-418359 Reduction of cytosolic Ca++ levels 5 LLUN000381-PA;LLUN001707-PA;LLUN005562-PA;LLUN005561-PA;LLUN002727-PA KEGG: 00720+1.1.1.42 Carbon fixation pathways in prokaryotes 1 LLUN012407-PA MetaCyc: PWY-6482 Diphthamide biosynthesis I (archaea) 2 LLUN009500-PA;LLUN008287-PA Reactome: R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin 25 LLUN006353-PA;LLUN011940-PA;LLUN011179-PA;LLUN006679-PA;LLUN010883-PA;LLUN003875-PA;LLUN000039-PA;LLUN003553-PA;LLUN004100-PA;LLUN011766-PA;LLUN009062-PA;LLUN004103-PA;LLUN009723-PA;LLUN002581-PA;LLUN003209-PA;LLUN008097-PA;LLUN007825-PA;LLUN003554-PA;LLUN006723-PA;LLUN008923-PA;LLUN001322-PA;LLUN002707-PA;LLUN000426-PA;LLUN000425-PA;LLUN003240-PA MetaCyc: PWY-6978 Plastoquinol-9 biosynthesis II 2 LLUN000584-PA;LLUN000136-PA Reactome: R-HSA-1369062 ABC transporters in lipid homeostasis 14 LLUN011131-PA;LLUN006507-PA;LLUN002186-PA;LLUN005786-PA;LLUN002139-PA;LLUN007085-PA;LLUN006520-PA;LLUN007667-PA;LLUN006549-PA;LLUN000612-PA;LLUN000250-PA;LLUN002138-PA;LLUN007112-PA;LLUN010462-PA KEGG: 00730+2.2.1.7 Thiamine metabolism 4 LLUN000747-PA;LLUN000032-PA;LLUN011427-PA;LLUN000909-PA MetaCyc: PWY-735 Jasmonic acid biosynthesis 1 LLUN000585-PA Reactome: R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 5 LLUN006111-PA;LLUN002475-PA;LLUN009115-PA;LLUN005530-PA;LLUN011046-PA MetaCyc: PWY-7863 Roseoflavin biosynthesis 1 LLUN000051-PA KEGG: 00270+6.3.2.2 Cysteine and methionine metabolism 2 LLUN009565-PA;LLUN007915-PA Reactome: R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 4 LLUN005530-PA;LLUN002369-PA;LLUN011465-PA;LLUN011466-PA KEGG: 00051+1.1.1.17 Fructose and mannose metabolism 1 LLUN006839-PA KEGG: 00550+2.4.1.227 Peptidoglycan biosynthesis 2 LLUN000041-PA;LLUN002437-PA KEGG: 00564+2.3.1.40 Glycerophospholipid metabolism 1 LLUN000161-PA KEGG: 00250+3.5.1.1 Alanine, aspartate and glutamate metabolism 1 LLUN010752-PA KEGG: 05170+2.7.11.1 Human immunodeficiency virus 1 infection 15 LLUN006440-PA;LLUN002957-PA;LLUN012849-PA;LLUN001111-PA;LLUN011312-PA;LLUN009503-PA;LLUN007485-PA;LLUN012841-PA;LLUN007496-PA;LLUN005145-PA;LLUN009259-PA;LLUN000510-PA;LLUN010447-PA;LLUN011988-PA;LLUN007666-PA Reactome: R-HSA-426117 Cation-coupled Chloride cotransporters 4 LLUN009655-PA;LLUN013151-PA;LLUN002770-PA;LLUN011800-PA KEGG: 04070+3.1.3.78 Phosphatidylinositol signaling system 2 LLUN008703-PA;LLUN003912-PA Reactome: R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 30 LLUN005530-PA;LLUN000089-PA;LLUN002894-PA;LLUN003629-PA;LLUN008477-PA;LLUN004706-PA;LLUN003215-PA;LLUN005030-PA;LLUN010012-PA;LLUN013272-PA;LLUN004508-PA;LLUN004794-PA;LLUN005610-PA;LLUN005593-PA;LLUN012548-PA;LLUN008960-PA;LLUN006525-PA;LLUN005440-PA;LLUN003501-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA;LLUN009994-PA;LLUN006627-PA;LLUN004861-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN008342-PA;LLUN002998-PA Reactome: R-HSA-2299718 Condensation of Prophase Chromosomes 1 LLUN009746-PA Reactome: R-HSA-110328 Recognition and association of DNA glycosylase with site containing an affected pyrimidine 4 LLUN002678-PA;LLUN005053-PA;LLUN000526-PA;LLUN000890-PA KEGG: 00130+2.1.1.163 Ubiquinone and other terpenoid-quinone biosynthesis 2 LLUN000579-PA;LLUN007379-PA Reactome: R-HSA-1474244 Extracellular matrix organization 1 LLUN004092-PA MetaCyc: PWY-6871 3-methylbutanol biosynthesis (engineered) 2 LLUN012888-PA;LLUN000046-PA MetaCyc: PWY-7199 Pyrimidine deoxyribonucleosides salvage 3 LLUN000163-PA;LLUN012848-PA;LLUN010665-PA MetaCyc: PWY-7437 Protein O-[N-acetyl]-glucosylation 4 LLUN003864-PA;LLUN009184-PA;LLUN013219-PA;LLUN000599-PA Reactome: R-HSA-917937 Iron uptake and transport 3 LLUN010186-PA;LLUN005530-PA;LLUN006111-PA KEGG: 00220+3.5.1.54 Arginine biosynthesis 1 LLUN001218-PA Reactome: R-HSA-4085011 Defective GNE causes sialuria, Nonaka myopathy and inclusion body myopathy 2 1 LLUN007276-PA Reactome: R-HSA-209968 Thyroxine biosynthesis 2 LLUN008890-PA;LLUN012791-PA Reactome: R-HSA-189451 Heme biosynthesis 13 LLUN000765-PA;LLUN000224-PA;LLUN010957-PA;LLUN012136-PA;LLUN004715-PA;LLUN009893-PA;LLUN005927-PA;LLUN000561-PA;LLUN012709-PA;LLUN008764-PA;LLUN000578-PA;LLUN011442-PA;LLUN010075-PA Reactome: R-HSA-2173788 Downregulation of TGF-beta receptor signaling 4 LLUN005530-PA;LLUN006654-PA;LLUN009748-PA;LLUN006158-PA MetaCyc: PWY-5966-1 Fatty acid biosynthesis initiation (animals and fungi, cytoplasm) 2 LLUN011458-PA;LLUN005463-PA MetaCyc: PWY-5661 GDP-glucose biosynthesis 1 LLUN009874-PA KEGG: 00760+2.4.2.1 Nicotinate and nicotinamide metabolism 1 LLUN000578-PA MetaCyc: PWY-6499 D-glucarate degradation II 2 LLUN000920-PA;LLUN000921-PA KEGG: 00720+4.2.1.2 Carbon fixation pathways in prokaryotes 3 LLUN012634-PA;LLUN000255-PA;LLUN005021-PA Reactome: R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 27 LLUN001235-PA;LLUN004016-PA;LLUN011675-PA;LLUN012442-PA;LLUN006050-PA;LLUN001234-PA;LLUN007787-PA;LLUN006665-PA;LLUN008795-PA;LLUN002027-PA;LLUN001639-PA;LLUN004803-PA;LLUN008841-PA;LLUN004207-PA;LLUN008644-PA;LLUN003325-PA;LLUN010444-PA;LLUN005720-PA;LLUN009443-PA;LLUN008616-PA;LLUN000459-PA;LLUN013016-PA;LLUN002109-PA;LLUN010569-PA;LLUN012918-PA;LLUN000492-PA;LLUN006049-PA Reactome: R-HSA-5689877 Josephin domain DUBs 4 LLUN005995-PA;LLUN005530-PA;LLUN002713-PA;LLUN011108-PA MetaCyc: PWY-6627 Salinosporamide A biosynthesis 1 LLUN000578-PA Reactome: R-HSA-6791055 TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P 4 LLUN010125-PA;LLUN006322-PA;LLUN000057-PA;LLUN000222-PA Reactome: R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 7 LLUN010402-PA;LLUN001208-PA;LLUN010125-PA;LLUN006122-PA;LLUN000222-PA;LLUN000057-PA;LLUN006322-PA Reactome: R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 1 LLUN002936-PA Reactome: R-HSA-68616 Assembly of the ORC complex at the origin of replication 3 LLUN007960-PA;LLUN004644-PA;LLUN004645-PA MetaCyc: PWY-1269 CMP-3-deoxy-D-manno-octulosonate biosynthesis 5 LLUN013139-PA;LLUN000339-PA;LLUN012135-PA;LLUN012864-PA;LLUN000102-PA Reactome: R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 9 LLUN001889-PA;LLUN013198-PA;LLUN013251-PA;LLUN006511-PA;LLUN010206-PA;LLUN011652-PA;LLUN002905-PA;LLUN010388-PA;LLUN004553-PA Reactome: R-HSA-909733 Interferon alpha/beta signaling 1 LLUN008416-PA Reactome: R-HSA-6798163 Choline catabolism 31 LLUN008813-PA;LLUN005231-PA;LLUN010789-PA;LLUN013163-PA;LLUN011888-PA;LLUN012851-PA;LLUN002324-PA;LLUN006119-PA;LLUN002321-PA;LLUN008188-PA;LLUN006047-PA;LLUN002166-PA;LLUN004107-PA;LLUN010781-PA;LLUN003953-PA;LLUN009710-PA;LLUN011666-PA;LLUN002094-PA;LLUN005232-PA;LLUN002164-PA;LLUN002325-PA;LLUN002213-PA;LLUN011278-PA;LLUN002323-PA;LLUN011634-PA;LLUN012123-PA;LLUN002322-PA;LLUN012260-PA;LLUN002326-PA;LLUN005233-PA;LLUN007712-PA KEGG: 00230+3.5.4.10+2.1.2.3 Purine metabolism 2 LLUN010078-PA;LLUN008637-PA MetaCyc: PWY-7533 Gliotoxin biosynthesis 11 LLUN013118-PA;LLUN003868-PA;LLUN000005-PA;LLUN005398-PA;LLUN004711-PA;LLUN005249-PA;LLUN003447-PA;LLUN008487-PA;LLUN000428-PA;LLUN008086-PA;LLUN007499-PA Reactome: R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 1 LLUN011749-PA KEGG: 00720+2.3.1.8 Carbon fixation pathways in prokaryotes 2 LLUN007189-PA;LLUN000223-PA KEGG: 00250+3.5.1.2 Alanine, aspartate and glutamate metabolism 1 LLUN009510-PA KEGG: 00270+2.3.1.30 Cysteine and methionine metabolism 1 LLUN000532-PA Reactome: R-HSA-9636003 NEIL3-mediated resolution of ICLs 1 LLUN000526-PA Reactome: R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 1 LLUN005823-PA KEGG: 00290+2.2.1.6 Valine, leucine and isoleucine biosynthesis 2 LLUN000044-PA;LLUN000551-PA Reactome: R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 1 LLUN000805-PA KEGG: 00230+5.4.2.7 Purine metabolism 1 LLUN000063-PA KEGG: 00500+3.2.1.1 Starch and sucrose metabolism 5 LLUN006388-PA;LLUN003576-PA;LLUN003575-PA;LLUN009051-PA;LLUN009050-PA KEGG: 00051+2.7.7.13 Fructose and mannose metabolism 1 LLUN000917-PA KEGG: 00750+1.4.3.5 Vitamin B6 metabolism 1 LLUN009995-PA Reactome: R-HSA-2046106 alpha-linolenic acid (ALA) metabolism 1 LLUN000759-PA MetaCyc: PWY-6372 1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium) 1 LLUN006316-PA Reactome: R-HSA-5662702 Melanin biosynthesis 17 LLUN011704-PA;LLUN009083-PA;LLUN011581-PA;LLUN006361-PA;LLUN002202-PA;LLUN003894-PA;LLUN012544-PA;LLUN012867-PA;LLUN005814-PA;LLUN002201-PA;LLUN010520-PA;LLUN009318-PA;LLUN002864-PA;LLUN009084-PA;LLUN010521-PA;LLUN004277-PA;LLUN004631-PA MetaCyc: PWY-7165 L-ascorbate biosynthesis VI (engineered pathway) 1 LLUN003801-PA Reactome: R-HSA-71737 Pyrophosphate hydrolysis 2 LLUN000272-PA;LLUN003630-PA MetaCyc: PWY-7230 Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast) 2 LLUN010266-PA;LLUN003684-PA MetaCyc: PWY-7197 Pyrimidine deoxyribonucleotide phosphorylation 7 LLUN000213-PA;LLUN011985-PA;LLUN012628-PA;LLUN005171-PA;LLUN012527-PA;LLUN006605-PA;LLUN006247-PA Reactome: R-HSA-5658442 Regulation of RAS by GAPs 32 LLUN003501-PA;LLUN005440-PA;LLUN012548-PA;LLUN008960-PA;LLUN010393-PA;LLUN011115-PA;LLUN012429-PA;LLUN002998-PA;LLUN006267-PA;LLUN002054-PA;LLUN009994-PA;LLUN004861-PA;LLUN000089-PA;LLUN004794-PA;LLUN007325-PA;LLUN005610-PA;LLUN008477-PA;LLUN003215-PA;LLUN004706-PA;LLUN010012-PA;LLUN006525-PA;LLUN008342-PA;LLUN009980-PA;LLUN006627-PA;LLUN002894-PA;LLUN005530-PA;LLUN008842-PA;LLUN004508-PA;LLUN005593-PA;LLUN003629-PA;LLUN013272-PA;LLUN005030-PA KEGG: 00230+2.7.1.40 Purine metabolism 2 LLUN007408-PA;LLUN013179-PA MetaCyc: PWY-3841 Folate transformations II (plants) 12 LLUN000777-PA;LLUN011200-PA;LLUN010882-PA;LLUN000209-PA;LLUN011129-PA;LLUN005962-PA;LLUN010665-PA;LLUN006558-PA;LLUN010048-PA;LLUN000141-PA;LLUN000163-PA;LLUN000542-PA Reactome: R-HSA-174403 Glutathione synthesis and recycling 10 LLUN008974-PA;LLUN011048-PA;LLUN002291-PA;LLUN012049-PA;LLUN008975-PA;LLUN007915-PA;LLUN005986-PA;LLUN006865-PA;LLUN000941-PA;LLUN009565-PA MetaCyc: PWY-7602 Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes) 18 LLUN000999-PA;LLUN011712-PA;LLUN002535-PA;LLUN003915-PA;LLUN004698-PA;LLUN003366-PA;LLUN004697-PA;LLUN002534-PA;LLUN008915-PA;LLUN011428-PA;LLUN001587-PA;LLUN001586-PA;LLUN003202-PA;LLUN009068-PA;LLUN001585-PA;LLUN005813-PA;LLUN011810-PA;LLUN003913-PA KEGG: 00030+2.2.1.2 Pentose phosphate pathway 4 LLUN000222-PA;LLUN000057-PA;LLUN006322-PA;LLUN010125-PA Reactome: R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 1 LLUN007485-PA KEGG: 00010+2.7.2.3 Glycolysis / Gluconeogenesis 2 LLUN000907-PA;LLUN010011-PA Reactome: R-HSA-5678895 Defective CFTR causes cystic fibrosis 32 LLUN003629-PA;LLUN004288-PA;LLUN005030-PA;LLUN013272-PA;LLUN004508-PA;LLUN005593-PA;LLUN005530-PA;LLUN002894-PA;LLUN009980-PA;LLUN006627-PA;LLUN008342-PA;LLUN006525-PA;LLUN008477-PA;LLUN004706-PA;LLUN003215-PA;LLUN010012-PA;LLUN004794-PA;LLUN005610-PA;LLUN000089-PA;LLUN011331-PA;LLUN002054-PA;LLUN006267-PA;LLUN009994-PA;LLUN004861-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN002998-PA;LLUN012548-PA;LLUN008960-PA;LLUN005440-PA;LLUN003501-PA Reactome: R-HSA-194313 VEGF ligand-receptor interactions 1 LLUN007166-PA Reactome: R-HSA-8853884 Transcriptional Regulation by VENTX 8 LLUN004076-PA;LLUN012097-PA;LLUN005309-PA;LLUN004685-PA;LLUN012273-PA;LLUN000845-PA;LLUN007882-PA;LLUN000848-PA KEGG: 00620+6.4.1.2 Pyruvate metabolism 2 LLUN011458-PA;LLUN005463-PA KEGG: 00950+2.6.1.1 Isoquinoline alkaloid biosynthesis 1 LLUN009219-PA KEGG: 00630+3.5.1.9 Glyoxylate and dicarboxylate metabolism 1 LLUN004035-PA KEGG: 00051+4.2.1.90 Fructose and mannose metabolism 1 LLUN000572-PA Reactome: R-HSA-5654693 FRS-mediated FGFR1 signaling 1 LLUN002128-PA KEGG: 00970+6.1.1.7 Aminoacyl-tRNA biosynthesis 4 LLUN010296-PA;LLUN004893-PA;LLUN004894-PA;LLUN000332-PA Reactome: R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 14 LLUN007911-PA;LLUN006359-PA;LLUN010205-PA;LLUN003293-PA;LLUN001290-PA;LLUN009871-PA;LLUN007985-PA;LLUN001676-PA;LLUN000521-PA;LLUN007829-PA;LLUN001167-PA;LLUN004049-PA;LLUN011849-PA;LLUN005850-PA MetaCyc: PWY-5895 Menaquinol-13 biosynthesis 2 LLUN007379-PA;LLUN000579-PA KEGG: 00130+2.5.1.39 Ubiquinone and other terpenoid-quinone biosynthesis 1 LLUN000136-PA Reactome: R-HSA-162699 Synthesis of dolichyl-phosphate mannose 1 LLUN006904-PA KEGG: 00051+2.7.1.105+3.1.3.46 Fructose and mannose metabolism 2 LLUN008694-PA;LLUN007337-PA Reactome: R-HSA-425381 Bicarbonate transporters 5 LLUN000106-PA;LLUN001206-PA;LLUN002384-PA;LLUN001842-PA;LLUN001841-PA MetaCyc: PWY-7279 Aerobic respiration II (cytochrome c) (yeast) 4 LLUN008348-PA;LLUN012663-PA;LLUN000260-PA;LLUN011041-PA Reactome: R-HSA-2022857 Keratan sulfate degradation 4 LLUN003183-PA;LLUN009341-PA;LLUN010383-PA;LLUN008090-PA MetaCyc: PWY-7255 Ergothioneine biosynthesis I (bacteria) 2 LLUN007915-PA;LLUN009565-PA MetaCyc: PWY-7124 Ethylene biosynthesis V (engineered) 4 LLUN012407-PA;LLUN000543-PA;LLUN000530-PA;LLUN012182-PA MetaCyc: PWY-7442 Drosopterin and aurodrosopterin biosynthesis 3 LLUN010032-PA;LLUN005541-PA;LLUN012034-PA Reactome: R-HSA-9649948 Signaling downstream of RAS mutants 2 LLUN011839-PA;LLUN002516-PA MetaCyc: PWY-7343 UDP-alpha-D-glucose biosynthesis I 1 LLUN009234-PA Reactome: R-HSA-4411364 Binding of TCF/LEF:CTNNB1 to target gene promoters 1 LLUN006125-PA Reactome: R-HSA-5576893 Phase 2 - plateau phase 5 LLUN012150-PA;LLUN008069-PA;LLUN011545-PA;LLUN000252-PA;LLUN005513-PA Reactome: R-HSA-70688 Proline catabolism 2 LLUN009509-PA;LLUN009954-PA Reactome: R-HSA-110362 POLB-Dependent Long Patch Base Excision Repair 1 LLUN008802-PA Reactome: R-HSA-112308 Presynaptic depolarization and calcium channel opening 2 LLUN000642-PA;LLUN000252-PA KEGG: 00260+2.6.1.52 Glycine, serine and threonine metabolism 3 LLUN000776-PA;LLUN012010-PA;LLUN011489-PA KEGG: 00561+2.7.1.30 Glycerolipid metabolism 3 LLUN000536-PA;LLUN005350-PA;LLUN008655-PA Reactome: R-HSA-1299308 Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) 1 LLUN006005-PA Reactome: R-HSA-1632852 Macroautophagy 18 LLUN007492-PA;LLUN010438-PA;LLUN009955-PA;LLUN006176-PA;LLUN012849-PA;LLUN001578-PA;LLUN005085-PA;LLUN011688-PA;LLUN004802-PA;LLUN006440-PA;LLUN008935-PA;LLUN008705-PA;LLUN009495-PA;LLUN005447-PA;LLUN011856-PA;LLUN003047-PA;LLUN007413-PA;LLUN011325-PA Reactome: R-HSA-427359 SIRT1 negatively regulates rRNA expression 1 LLUN004991-PA Reactome: R-HSA-400206 Regulation of lipid metabolism by PPARalpha 3 LLUN005720-PA;LLUN012442-PA;LLUN004016-PA Reactome: R-HSA-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells 3 LLUN009496-PA;LLUN009497-PA;LLUN009498-PA KEGG: 00473+5.1.1.1 D-Alanine metabolism 3 LLUN000915-PA;LLUN000131-PA;LLUN005700-PA Reactome: R-HSA-180585 Vif-mediated degradation of APOBEC3G 30 LLUN005530-PA;LLUN000089-PA;LLUN002894-PA;LLUN003629-PA;LLUN008477-PA;LLUN003215-PA;LLUN005030-PA;LLUN004706-PA;LLUN010012-PA;LLUN013272-PA;LLUN004508-PA;LLUN004794-PA;LLUN005610-PA;LLUN005593-PA;LLUN012548-PA;LLUN008960-PA;LLUN006525-PA;LLUN005440-PA;LLUN003501-PA;LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN006627-PA;LLUN009994-PA;LLUN004861-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN008342-PA;LLUN002998-PA MetaCyc: PWY-6352 3-phosphoinositide biosynthesis 1 LLUN006224-PA Reactome: R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 25 LLUN003240-PA;LLUN003047-PA;LLUN012444-PA;LLUN007852-PA;LLUN001322-PA;LLUN002707-PA;LLUN011106-PA;LLUN002936-PA;LLUN008923-PA;LLUN006723-PA;LLUN007825-PA;LLUN002928-PA;LLUN003554-PA;LLUN007830-PA;LLUN003209-PA;LLUN002581-PA;LLUN000039-PA;LLUN006353-PA;LLUN011179-PA;LLUN007564-PA;LLUN003553-PA;LLUN003747-PA;LLUN011766-PA;LLUN004100-PA;LLUN009062-PA KEGG: 00270+6.3.2.3 Cysteine and methionine metabolism 4 LLUN000913-PA;LLUN008975-PA;LLUN008974-PA;LLUN012049-PA MetaCyc: PWY-5514 UDP-N-acetyl-D-galactosamine biosynthesis II 5 LLUN004963-PA;LLUN000137-PA;LLUN007276-PA;LLUN009874-PA;LLUN001188-PA Reactome: R-HSA-8951911 RUNX3 regulates RUNX1-mediated transcription 3 LLUN009498-PA;LLUN009496-PA;LLUN009497-PA Reactome: R-HSA-73863 RNA Polymerase I Transcription Termination 14 LLUN002995-PA;LLUN007911-PA;LLUN010529-PA;LLUN001565-PA;LLUN001290-PA;LLUN009871-PA;LLUN001676-PA;LLUN010911-PA;LLUN000521-PA;LLUN012654-PA;LLUN001301-PA;LLUN010602-PA;LLUN008353-PA;LLUN011477-PA Reactome: R-HSA-8948216 Collagen chain trimerization 3 LLUN004092-PA;LLUN013127-PA;LLUN002886-PA Reactome: R-HSA-5632681 Ligand-receptor interactions 3 LLUN005656-PA;LLUN010850-PA;LLUN001628-PA KEGG: 00052+4.1.2.40 Galactose metabolism 1 LLUN000895-PA Reactome: R-HSA-72649 Translation initiation complex formation 31 LLUN002287-PA;LLUN006098-PA;LLUN008357-PA;LLUN007425-PA;LLUN005530-PA;LLUN001948-PA;LLUN001569-PA;LLUN003999-PA;LLUN002560-PA;LLUN004682-PA;LLUN006512-PA;LLUN003033-PA;LLUN003745-PA;LLUN009177-PA;LLUN000340-PA;LLUN000856-PA;LLUN004621-PA;LLUN012053-PA;LLUN008680-PA;LLUN011199-PA;LLUN004513-PA;LLUN001670-PA;LLUN003373-PA;LLUN006863-PA;LLUN012611-PA;LLUN007563-PA;LLUN005308-PA;LLUN012076-PA;LLUN007100-PA;LLUN007812-PA;LLUN004402-PA MetaCyc: PWY-6803 Phosphatidylcholine acyl editing 7 LLUN008580-PA;LLUN000563-PA;LLUN001410-PA;LLUN001370-PA;LLUN003536-PA;LLUN003919-PA;LLUN008242-PA Reactome: R-HSA-6783310 Fanconi Anemia Pathway 20 LLUN005061-PA;LLUN008038-PA;LLUN008182-PA;LLUN002277-PA;LLUN011604-PA;LLUN010436-PA;LLUN003095-PA;LLUN008476-PA;LLUN005530-PA;LLUN012618-PA;LLUN003301-PA;LLUN005749-PA;LLUN006969-PA;LLUN009917-PA;LLUN008091-PA;LLUN007833-PA;LLUN007180-PA;LLUN005828-PA;LLUN009712-PA;LLUN003218-PA MetaCyc: PWY-7417 Phospholipid remodeling (phosphatidate, yeast) 9 LLUN008689-PA;LLUN003919-PA;LLUN008580-PA;LLUN000563-PA;LLUN001410-PA;LLUN001370-PA;LLUN003536-PA;LLUN008242-PA;LLUN000308-PA KEGG: 00970+6.1.1.20 Aminoacyl-tRNA biosynthesis 5 LLUN007746-PA;LLUN012047-PA;LLUN011446-PA;LLUN012421-PA;LLUN005052-PA Reactome: R-HSA-192823 Viral mRNA Translation 61 LLUN009774-PA;LLUN008357-PA;LLUN010358-PA;LLUN005530-PA;LLUN009998-PA;LLUN012333-PA;LLUN002560-PA;LLUN008530-PA;LLUN006512-PA;LLUN010052-PA;LLUN000494-PA;LLUN008995-PA;LLUN000340-PA;LLUN002390-PA;LLUN012611-PA;LLUN003780-PA;LLUN007563-PA;LLUN005442-PA;LLUN012390-PA;LLUN010136-PA;LLUN004193-PA;LLUN004909-PA;LLUN005586-PA;LLUN007812-PA;LLUN007661-PA;LLUN010153-PA;LLUN002287-PA;LLUN006098-PA;LLUN007733-PA;LLUN011174-PA;LLUN003524-PA;LLUN003497-PA;LLUN005084-PA;LLUN003515-PA;LLUN012495-PA;LLUN008152-PA;LLUN001569-PA;LLUN010350-PA;LLUN006279-PA;LLUN008597-PA;LLUN009419-PA;LLUN009177-PA;LLUN003745-PA;LLUN003033-PA;LLUN007972-PA;LLUN001670-PA;LLUN012053-PA;LLUN000856-PA;LLUN006863-PA;LLUN001675-PA;LLUN003373-PA;LLUN012474-PA;LLUN002787-PA;LLUN005594-PA;LLUN004402-PA;LLUN011304-PA;LLUN007100-PA;LLUN006093-PA;LLUN000493-PA;LLUN012076-PA;LLUN004837-PA KEGG: 00630+6.3.1.2 Glyoxylate and dicarboxylate metabolism 4 LLUN002238-PA;LLUN000514-PA;LLUN002676-PA;LLUN000515-PA MetaCyc: PWY-7221 Guanosine ribonucleotides de novo biosynthesis 14 LLUN012527-PA;LLUN008234-PA;LLUN003702-PA;LLUN000036-PA;LLUN000213-PA;LLUN006247-PA;LLUN000522-PA;LLUN000215-PA;LLUN002619-PA;LLUN011985-PA;LLUN012628-PA;LLUN009293-PA;LLUN005804-PA;LLUN006961-PA Reactome: R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 69 LLUN003033-PA;LLUN008597-PA;LLUN010350-PA;LLUN008152-PA;LLUN003515-PA;LLUN003524-PA;LLUN005084-PA;LLUN003497-PA;LLUN006098-PA;LLUN007100-PA;LLUN006093-PA;LLUN000493-PA;LLUN012076-PA;LLUN004402-PA;LLUN005594-PA;LLUN008815-PA;LLUN006672-PA;LLUN001675-PA;LLUN012053-PA;LLUN000856-PA;LLUN007972-PA;LLUN006512-PA;LLUN008530-PA;LLUN002560-PA;LLUN008357-PA;LLUN005586-PA;LLUN007812-PA;LLUN004193-PA;LLUN012390-PA;LLUN005442-PA;LLUN002390-PA;LLUN012611-PA;LLUN003780-PA;LLUN000494-PA;LLUN010052-PA;LLUN009419-PA;LLUN009177-PA;LLUN006179-PA;LLUN003745-PA;LLUN006279-PA;LLUN001569-PA;LLUN012495-PA;LLUN002287-PA;LLUN010153-PA;LLUN011174-PA;LLUN007733-PA;LLUN007661-PA;LLUN011304-PA;LLUN004837-PA;LLUN003577-PA;LLUN012474-PA;LLUN002787-PA;LLUN006863-PA;LLUN003373-PA;LLUN001670-PA;LLUN009131-PA;LLUN006805-PA;LLUN012333-PA;LLUN004262-PA;LLUN005530-PA;LLUN009998-PA;LLUN009774-PA;LLUN010358-PA;LLUN004909-PA;LLUN010136-PA;LLUN009503-PA;LLUN007563-PA;LLUN008995-PA;LLUN000340-PA MetaCyc: PWY-1722 Formate assimilation into 5,10-methylenetetrahydrofolate 4 LLUN011200-PA;LLUN010882-PA;LLUN005962-PA;LLUN000777-PA Reactome: R-HSA-182971 EGFR downregulation 3 LLUN005530-PA;LLUN006122-PA;LLUN012461-PA KEGG: 00970+6.1.1.17 Aminoacyl-tRNA biosynthesis 2 LLUN000232-PA;LLUN009306-PA Reactome: R-HSA-193692 Regulated proteolysis of p75NTR 3 LLUN007104-PA;LLUN003449-PA;LLUN001957-PA MetaCyc: PWY-381 Nitrate reduction II (assimilatory) 4 LLUN002238-PA;LLUN002676-PA;LLUN000514-PA;LLUN000515-PA MetaCyc: PWY-7379 Mrna capping II 1 LLUN011672-PA Reactome: R-HSA-427589 Type II Na+/Pi cotransporters 1 LLUN000139-PA Reactome: R-HSA-6804760 Regulation of TP53 Activity through Methylation 4 LLUN005530-PA;LLUN007240-PA;LLUN003218-PA;LLUN005901-PA MetaCyc: PWY-7921 Protein O-mannosylation I (yeast) 5 LLUN006904-PA;LLUN006126-PA;LLUN008266-PA;LLUN004843-PA;LLUN004509-PA KEGG: 00230+6.3.4.4 Purine metabolism 1 LLUN000266-PA Reactome: R-HSA-114508 Effects of PIP2 hydrolysis 3 LLUN004972-PA;LLUN012411-PA;LLUN001142-PA Reactome: R-HSA-5221030 TET1,2,3 and TDG demethylate DNA 2 LLUN002678-PA;LLUN002838-PA KEGG: 00510+2.7.8.15 N-Glycan biosynthesis 1 LLUN011947-PA Reactome: R-HSA-72165 mRNA Splicing - Minor Pathway 21 LLUN009871-PA;LLUN009131-PA;LLUN005558-PA;LLUN001750-PA;LLUN000400-PA;LLUN007911-PA;LLUN001711-PA;LLUN000638-PA;LLUN001676-PA;LLUN009483-PA;LLUN009178-PA;LLUN000521-PA;LLUN013182-PA;LLUN012874-PA;LLUN002884-PA;LLUN001654-PA;LLUN011861-PA;LLUN000235-PA;LLUN003733-PA;LLUN003782-PA;LLUN001290-PA MetaCyc: PWY-7307 Oleate beta-oxidation (reductase-dependent, yeast) 1 LLUN000586-PA KEGG: 00230+1.1.1.205 Purine metabolism 2 LLUN008234-PA;LLUN000036-PA Reactome: R-HSA-70263 Gluconeogenesis 16 LLUN000535-PA;LLUN000276-PA;LLUN011949-PA;LLUN012438-PA;LLUN007441-PA;LLUN008377-PA;LLUN010011-PA;LLUN009807-PA;LLUN000273-PA;LLUN000832-PA;LLUN009867-PA;LLUN000137-PA;LLUN012182-PA;LLUN000907-PA;LLUN003283-PA;LLUN000908-PA Reactome: R-HSA-2644607 Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling 1 LLUN006111-PA Reactome: R-HSA-73980 RNA Polymerase III Transcription Termination 13 LLUN002544-PA;LLUN009871-PA;LLUN007985-PA;LLUN001676-PA;LLUN000521-PA;LLUN007829-PA;LLUN001167-PA;LLUN005850-PA;LLUN011849-PA;LLUN007911-PA;LLUN006359-PA;LLUN003293-PA;LLUN001290-PA Reactome: R-HSA-901032 ER Quality Control Compartment (ERQC) 2 LLUN004161-PA;LLUN005530-PA KEGG: 05163+2.7.11.1 Human cytomegalovirus infection 15 LLUN001111-PA;LLUN012849-PA;LLUN011312-PA;LLUN006440-PA;LLUN002957-PA;LLUN009259-PA;LLUN005145-PA;LLUN012841-PA;LLUN007496-PA;LLUN007485-PA;LLUN009503-PA;LLUN010447-PA;LLUN000510-PA;LLUN007666-PA;LLUN011988-PA MetaCyc: PWY-6748 Nitrate reduction VII (denitrification) 1 LLUN011553-PA Reactome: R-HSA-111465 Apoptotic cleavage of cellular proteins 1 LLUN012179-PA KEGG: 00250+1.4.1.1 Alanine, aspartate and glutamate metabolism 1 LLUN013118-PA MetaCyc: PWY-5485 Pyruvate fermentation to acetate IV 3 LLUN000223-PA;LLUN007189-PA;LLUN009622-PA KEGG: 00261+1.17.1.8 Monobactam biosynthesis 1 LLUN000049-PA Reactome: R-HSA-9652282 Drug-mediated inhibition of ERBB2 signaling 2 LLUN008205-PA;LLUN008416-PA MetaCyc: PWY-6840 Homoglutathione biosynthesis 2 LLUN009565-PA;LLUN007915-PA MetaCyc: PWY-5872 Ubiquinol-10 biosynthesis (eukaryotic) 3 LLUN010266-PA;LLUN003684-PA;LLUN000136-PA KEGG: 00562+3.1.3.36 Inositol phosphate metabolism 1 LLUN011415-PA KEGG: 00330+4.1.1.50 Arginine and proline metabolism 3 LLUN006330-PA;LLUN010564-PA;LLUN001283-PA Reactome: R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 71 LLUN005594-PA;LLUN006093-PA;LLUN012076-PA;LLUN000493-PA;LLUN007100-PA;LLUN004402-PA;LLUN004621-PA;LLUN000856-PA;LLUN008680-PA;LLUN012053-PA;LLUN007972-PA;LLUN001675-PA;LLUN008597-PA;LLUN010350-PA;LLUN003999-PA;LLUN008152-PA;LLUN003033-PA;LLUN006098-PA;LLUN003515-PA;LLUN003497-PA;LLUN005084-PA;LLUN003524-PA;LLUN012390-PA;LLUN007812-PA;LLUN005586-PA;LLUN004193-PA;LLUN000494-PA;LLUN011199-PA;LLUN004513-PA;LLUN010052-PA;LLUN005442-PA;LLUN002390-PA;LLUN003780-PA;LLUN012611-PA;LLUN002560-PA;LLUN008530-PA;LLUN006512-PA;LLUN011029-PA;LLUN008357-PA;LLUN002787-PA;LLUN012474-PA;LLUN005308-PA;LLUN004837-PA;LLUN011304-PA;LLUN001670-PA;LLUN003373-PA;LLUN006863-PA;LLUN001948-PA;LLUN006279-PA;LLUN001569-PA;LLUN004682-PA;LLUN003745-PA;LLUN009177-PA;LLUN009419-PA;LLUN011174-PA;LLUN007733-PA;LLUN010153-PA;LLUN002287-PA;LLUN007661-PA;LLUN012495-PA;LLUN004909-PA;LLUN010136-PA;LLUN000340-PA;LLUN008995-PA;LLUN007563-PA;LLUN012333-PA;LLUN010358-PA;LLUN009774-PA;LLUN009998-PA;LLUN007425-PA;LLUN005530-PA KEGG: 00260+5.4.2.11 Glycine, serine and threonine metabolism 2 LLUN008352-PA;LLUN010054-PA Reactome: R-HSA-8941326 RUNX2 regulates bone development 3 LLUN009497-PA;LLUN009496-PA;LLUN009498-PA MetaCyc: PWY-5844 Menaquinol-9 biosynthesis 2 LLUN000579-PA;LLUN007379-PA Reactome: R-HSA-901042 Calnexin/calreticulin cycle 1 LLUN006087-PA KEGG: 00561+2.7.7.9 Glycerolipid metabolism 1 LLUN009234-PA Reactome: R-HSA-8964208 Phenylalanine metabolism 1 LLUN010752-PA MetaCyc: PWY-6897 Thiamine salvage II 1 LLUN000288-PA MetaCyc: PWY-7269 NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast) 1 LLUN008323-PA MetaCyc: PWY-7790 UMP biosynthesis II 5 LLUN006557-PA;LLUN000049-PA;LLUN009630-PA;LLUN000087-PA;LLUN004225-PA MetaCyc: PWY-6654 Phosphopantothenate biosynthesis III (archaebacteria) 3 LLUN000749-PA;LLUN007480-PA;LLUN011706-PA Reactome: R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network 12 LLUN001927-PA;LLUN010728-PA;LLUN010648-PA;LLUN011584-PA;LLUN003718-PA;LLUN006756-PA;LLUN005443-PA;LLUN003728-PA;LLUN011619-PA;LLUN006589-PA;LLUN000729-PA;LLUN003429-PA MetaCyc: PWY-6562 Norspermidine biosynthesis 1 LLUN008772-PA KEGG: 04070+2.7.11.13 Phosphatidylinositol signaling system 2 LLUN005092-PA;LLUN008972-PA Reactome: R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 105 LLUN000178-PA;LLUN011876-PA;LLUN012390-PA;LLUN004193-PA;LLUN012957-PA;LLUN006028-PA;LLUN005586-PA;LLUN007812-PA;LLUN004647-PA;LLUN010052-PA;LLUN000494-PA;LLUN004004-PA;LLUN002390-PA;LLUN012611-PA;LLUN003780-PA;LLUN005442-PA;LLUN002560-PA;LLUN007741-PA;LLUN005532-PA;LLUN007574-PA;LLUN012229-PA;LLUN010668-PA;LLUN006512-PA;LLUN011059-PA;LLUN008530-PA;LLUN002089-PA;LLUN008357-PA;LLUN003823-PA;LLUN006957-PA;LLUN010530-PA;LLUN005594-PA;LLUN004402-PA;LLUN007666-PA;LLUN006093-PA;LLUN012076-PA;LLUN011703-PA;LLUN000493-PA;LLUN007100-PA;LLUN007972-PA;LLUN000856-PA;LLUN012053-PA;LLUN012528-PA;LLUN001675-PA;LLUN008152-PA;LLUN010350-PA;LLUN008597-PA;LLUN003033-PA;LLUN008955-PA;LLUN009365-PA;LLUN007120-PA;LLUN006098-PA;LLUN005084-PA;LLUN003497-PA;LLUN003524-PA;LLUN004620-PA;LLUN003515-PA;LLUN008399-PA;LLUN012517-PA;LLUN001734-PA;LLUN000286-PA;LLUN010136-PA;LLUN006232-PA;LLUN004909-PA;LLUN012539-PA;LLUN000340-PA;LLUN008995-PA;LLUN002536-PA;LLUN004817-PA;LLUN007563-PA;LLUN012333-PA;LLUN010358-PA;LLUN009774-PA;LLUN009998-PA;LLUN005530-PA;LLUN002787-PA;LLUN012474-PA;LLUN011054-PA;LLUN004837-PA;LLUN008601-PA;LLUN009681-PA;LLUN010368-PA;LLUN011304-PA;LLUN001670-PA;LLUN003373-PA;LLUN004390-PA;LLUN006863-PA;LLUN001569-PA;LLUN006279-PA;LLUN008540-PA;LLUN003745-PA;LLUN009419-PA;LLUN009177-PA;LLUN011877-PA;LLUN002957-PA;LLUN002286-PA;LLUN002357-PA;LLUN007661-PA;LLUN007733-PA;LLUN011174-PA;LLUN008545-PA;LLUN002287-PA;LLUN010153-PA;LLUN010723-PA;LLUN005975-PA;LLUN012495-PA KEGG: 00564+3.1.1.4+3.1.1.5 Glycerophospholipid metabolism 1 LLUN003919-PA MetaCyc: PWY-7817 Type I lipoteichoic acid biosynthesis (S. aureus) 5 LLUN012411-PA;LLUN009234-PA;LLUN009855-PA;LLUN000135-PA;LLUN001142-PA KEGG: 00760+1.4.3.16 Nicotinate and nicotinamide metabolism 1 LLUN000889-PA Reactome: R-HSA-9657050 Defective OGG1 Localization 1 LLUN005053-PA KEGG: 00531+3.2.1.50 Glycosaminoglycan degradation 1 LLUN011339-PA Reactome: R-HSA-9017802 Noncanonical activation of NOTCH3 3 LLUN001957-PA;LLUN003449-PA;LLUN007104-PA KEGG: 00640+2.3.1.8 Propanoate metabolism 2 LLUN000223-PA;LLUN007189-PA Reactome: R-HSA-8847993 ERBB2 Activates PTK6 Signaling 1 LLUN000021-PA Reactome: R-HSA-5674499 Negative feedback regulation of MAPK pathway 1 LLUN002516-PA Reactome: R-HSA-913709 O-linked glycosylation of mucins 14 LLUN011454-PA;LLUN012887-PA;LLUN003093-PA;LLUN005165-PA;LLUN009810-PA;LLUN008088-PA;LLUN011445-PA;LLUN004612-PA;LLUN000527-PA;LLUN006561-PA;LLUN008257-PA;LLUN006973-PA;LLUN000863-PA;LLUN006904-PA KEGG: 00270+4.2.1.109 Cysteine and methionine metabolism 1 LLUN000196-PA Reactome: R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 1 LLUN005530-PA Reactome: R-HSA-171319 Telomere Extension By Telomerase 3 LLUN007834-PA;LLUN007570-PA;LLUN010636-PA KEGG: 00400+5.3.1.24 Phenylalanine, tyrosine and tryptophan biosynthesis 1 LLUN012018-PA Reactome: R-HSA-5467337 APC truncation mutants have impaired AXIN binding 1 LLUN011378-PA MetaCyc: PWY-5316 Nicotine biosynthesis 2 LLUN000035-PA;LLUN000889-PA Reactome: R-HSA-9620244 Long-term potentiation 2 LLUN011839-PA;LLUN008044-PA KEGG: 00710+5.3.1.1 Carbon fixation in photosynthetic organisms 2 LLUN009807-PA;LLUN000535-PA Reactome: R-HSA-1614635 Sulfur amino acid metabolism 3 LLUN000141-PA;LLUN002379-PA;LLUN000281-PA Reactome: R-HSA-977347 Serine biosynthesis 8 LLUN000073-PA;LLUN011489-PA;LLUN006711-PA;LLUN004114-PA;LLUN000062-PA;LLUN000776-PA;LLUN012010-PA;LLUN009374-PA KEGG: 00760+6.3.4.21 Nicotinate and nicotinamide metabolism 3 LLUN009089-PA;LLUN012146-PA;LLUN000035-PA KEGG: 00240+2.4.2.1 Pyrimidine metabolism 1 LLUN000578-PA MetaCyc: PWY-7511 Protein ubiquitination 50 LLUN010590-PA;LLUN000875-PA;LLUN003566-PA;LLUN012594-PA;LLUN004293-PA;LLUN004683-PA;LLUN007817-PA;LLUN012494-PA;LLUN010738-PA;LLUN003328-PA;LLUN009423-PA;LLUN004312-PA;LLUN005662-PA;LLUN008472-PA;LLUN007204-PA;LLUN002080-PA;LLUN001737-PA;LLUN010367-PA;LLUN000589-PA;LLUN010945-PA;LLUN004101-PA;LLUN011993-PA;LLUN005007-PA;LLUN007569-PA;LLUN005642-PA;LLUN011975-PA;LLUN007510-PA;LLUN006855-PA;LLUN012657-PA;LLUN007958-PA;LLUN006492-PA;LLUN006158-PA;LLUN006026-PA;LLUN010592-PA;LLUN011251-PA;LLUN004343-PA;LLUN012197-PA;LLUN004464-PA;LLUN003269-PA;LLUN004829-PA;LLUN008886-PA;LLUN010116-PA;LLUN002718-PA;LLUN012959-PA;LLUN007715-PA;LLUN008888-PA;LLUN009628-PA;LLUN005955-PA;LLUN011934-PA;LLUN004292-PA KEGG: 00521+3.1.3.25 Streptomycin biosynthesis 2 LLUN003712-PA;LLUN000211-PA Reactome: R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 12 LLUN006020-PA;LLUN004888-PA;LLUN000692-PA;LLUN011163-PA;LLUN000563-PA;LLUN010205-PA;LLUN003498-PA;LLUN000062-PA;LLUN002154-PA;LLUN011433-PA;LLUN012760-PA;LLUN012819-PA KEGG: 00630+1.1.1.37 Glyoxylate and dicarboxylate metabolism 3 LLUN012438-PA;LLUN009867-PA;LLUN000276-PA Reactome: R-HSA-77387 Insulin receptor recycling 13 LLUN012460-PA;LLUN012577-PA;LLUN012843-PA;LLUN004087-PA;LLUN005072-PA;LLUN002836-PA;LLUN010285-PA;LLUN004638-PA;LLUN004088-PA;LLUN002241-PA;LLUN002284-PA;LLUN005731-PA;LLUN005643-PA MetaCyc: PWY-621 Sucrose degradation III (sucrose invertase) 2 LLUN009874-PA;LLUN000137-PA KEGG: 00400+2.5.1.54 Phenylalanine, tyrosine and tryptophan biosynthesis 2 LLUN012864-PA;LLUN000339-PA MetaCyc: PWY-5133 Colupulone and cohumulone biosynthesis 2 LLUN000254-PA;LLUN001912-PA KEGG: 00730+3.1.3.1 Thiamine metabolism 12 LLUN002237-PA;LLUN008172-PA;LLUN008359-PA;LLUN011373-PA;LLUN006397-PA;LLUN006398-PA;LLUN008360-PA;LLUN012626-PA;LLUN002910-PA;LLUN005387-PA;LLUN006399-PA;LLUN006396-PA Reactome: R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 2 LLUN002516-PA;LLUN011839-PA MetaCyc: PWY-5890 Menaquinol-10 biosynthesis 2 LLUN007379-PA;LLUN000579-PA MetaCyc: PWY-7118 Chitin degradation to ethanol 5 LLUN007673-PA;LLUN000144-PA;LLUN000254-PA;LLUN012888-PA;LLUN001912-PA KEGG: 00230+3.5.3.4 Purine metabolism 1 LLUN006292-PA MetaCyc: PWY-6644 Fluoroacetate and fluorothreonine biosynthesis 1 LLUN000578-PA KEGG: 04150+2.7.1.153 mTOR signaling pathway 1 LLUN006224-PA Reactome: R-HSA-163841 Gamma carboxylation, hypusine formation and arylsulfatase activation 1 LLUN009402-PA KEGG: 04070+3.1.4.11 Phosphatidylinositol signaling system 3 LLUN004409-PA;LLUN007371-PA;LLUN008499-PA MetaCyc: PWY-2723 Trehalose degradation V 1 LLUN009874-PA Reactome: R-HSA-5689901 Metalloprotease DUBs 2 LLUN005530-PA;LLUN012395-PA KEGG: 00950+1.14.16.2 Isoquinoline alkaloid biosynthesis 1 LLUN000709-PA Reactome: R-HSA-2514853 Condensation of Prometaphase Chromosomes 2 LLUN008475-PA;LLUN009746-PA KEGG: 00270+1.13.11.54 Cysteine and methionine metabolism 1 LLUN003319-PA KEGG: 00511+3.2.1.51 Other glycan degradation 3 LLUN005137-PA;LLUN005138-PA;LLUN012652-PA KEGG: 00562+2.7.1.153 Inositol phosphate metabolism 1 LLUN006224-PA MetaCyc: PWY-6610 Adenine salvage 1 LLUN006332-PA Reactome: R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 3 LLUN005530-PA;LLUN008416-PA;LLUN008205-PA Reactome: R-HSA-350054 Notch-HLH transcription pathway 8 LLUN010803-PA;LLUN010873-PA;LLUN002369-PA;LLUN011364-PA;LLUN011136-PA;LLUN010902-PA;LLUN003873-PA;LLUN003131-PA Reactome: R-HSA-9603505 NTRK3 as a dependence receptor 1 LLUN011586-PA KEGG: 00020+2.3.3.8 Citrate cycle (TCA cycle) 1 LLUN007878-PA KEGG: 00983+3.6.1.23 Drug metabolism - other enzymes 1 LLUN000524-PA Reactome: R-HSA-2559585 Oncogene Induced Senescence 3 LLUN005530-PA;LLUN002516-PA;LLUN005309-PA KEGG: 00680+4.4.1.22 Methane metabolism 1 LLUN009769-PA Reactome: R-HSA-382556 ABC-family proteins mediated transport 32 LLUN005610-PA;LLUN004794-PA;LLUN004706-PA;LLUN003215-PA;LLUN010012-PA;LLUN008477-PA;LLUN011331-PA;LLUN000089-PA;LLUN002998-PA;LLUN010393-PA;LLUN011115-PA;LLUN012429-PA;LLUN009994-PA;LLUN004861-PA;LLUN006267-PA;LLUN002054-PA;LLUN005440-PA;LLUN003501-PA;LLUN008960-PA;LLUN012548-PA;LLUN005593-PA;LLUN004508-PA;LLUN005030-PA;LLUN013272-PA;LLUN003629-PA;LLUN004288-PA;LLUN002894-PA;LLUN005530-PA;LLUN008342-PA;LLUN006627-PA;LLUN009980-PA;LLUN006525-PA KEGG: 00564+3.1.1.4 Glycerophospholipid metabolism 5 LLUN003536-PA;LLUN001370-PA;LLUN008242-PA;LLUN008580-PA;LLUN001410-PA MetaCyc: PWY-7383 Anaerobic energy metabolism (invertebrates, cytosol) 10 LLUN007408-PA;LLUN013179-PA;LLUN009867-PA;LLUN000276-PA;LLUN000915-PA;LLUN003283-PA;LLUN009219-PA;LLUN000131-PA;LLUN005700-PA;LLUN012438-PA Reactome: R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 4 LLUN006578-PA;LLUN000235-PA;LLUN002884-PA;LLUN009131-PA MetaCyc: PWY-6728 Methylaspartate cycle 18 LLUN005021-PA;LLUN000260-PA;LLUN012993-PA;LLUN012634-PA;LLUN012438-PA;LLUN008348-PA;LLUN003300-PA;LLUN012663-PA;LLUN011041-PA;LLUN000276-PA;LLUN012407-PA;LLUN011264-PA;LLUN007879-PA;LLUN007878-PA;LLUN000255-PA;LLUN007880-PA;LLUN008350-PA;LLUN009867-PA Reactome: R-HSA-8853383 Lysosomal oligosaccharide catabolism 4 LLUN003190-PA;LLUN004449-PA;LLUN010386-PA;LLUN002669-PA KEGG: 00052+2.7.1.1 Galactose metabolism 2 LLUN005483-PA;LLUN003849-PA MetaCyc: PWY-7587 Oleate biosynthesis III (cyanobacteria) 2 LLUN000308-PA;LLUN008689-PA Reactome: R-HSA-4341670 Defective NEU1 causes sialidosis 5 LLUN006287-PA;LLUN005178-PA;LLUN006286-PA;LLUN006288-PA;LLUN012575-PA Reactome: R-HSA-937042 IRAK2 mediated activation of TAK1 complex 1 LLUN005530-PA KEGG: 00620+2.3.3.9 Pyruvate metabolism 2 LLUN000144-PA;LLUN007673-PA Reactome: R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 1 LLUN002907-PA MetaCyc: PWY-5723 Rubisco shunt 12 LLUN010698-PA;LLUN000530-PA;LLUN000057-PA;LLUN010125-PA;LLUN012182-PA;LLUN000222-PA;LLUN006322-PA;LLUN000903-PA;LLUN013179-PA;LLUN007784-PA;LLUN007408-PA;LLUN010699-PA KEGG: 00260+2.1.2.10 Glycine, serine and threonine metabolism 1 LLUN008929-PA Reactome: R-HSA-210500 Glutamate Neurotransmitter Release Cycle 2 LLUN009510-PA;LLUN011055-PA Reactome: R-HSA-167172 Transcription of the HIV genome 26 LLUN007911-PA;LLUN008159-PA;LLUN008863-PA;LLUN007705-PA;LLUN001565-PA;LLUN008198-PA;LLUN009871-PA;LLUN004030-PA;LLUN010602-PA;LLUN001301-PA;LLUN012654-PA;LLUN006269-PA;LLUN005474-PA;LLUN011861-PA;LLUN002995-PA;LLUN001654-PA;LLUN001290-PA;LLUN011583-PA;LLUN008199-PA;LLUN009178-PA;LLUN010911-PA;LLUN001676-PA;LLUN007987-PA;LLUN008353-PA;LLUN009851-PA;LLUN000521-PA Reactome: R-HSA-8964572 Lipid particle organization 1 LLUN002398-PA KEGG: 00280+4.2.1.17+1.1.1.35 Valine, leucine and isoleucine degradation 4 LLUN011561-PA;LLUN007706-PA;LLUN008953-PA;LLUN000586-PA Reactome: R-HSA-975634 Retinoid metabolism and transport 4 LLUN003919-PA;LLUN009875-PA;LLUN004191-PA;LLUN002060-PA Reactome: R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 21 LLUN001676-PA;LLUN009178-PA;LLUN010911-PA;LLUN000521-PA;LLUN008353-PA;LLUN007798-PA;LLUN001654-PA;LLUN002995-PA;LLUN009747-PA;LLUN011861-PA;LLUN001290-PA;LLUN009131-PA;LLUN009871-PA;LLUN002218-PA;LLUN010602-PA;LLUN001301-PA;LLUN012654-PA;LLUN011586-PA;LLUN009648-PA;LLUN007911-PA;LLUN001565-PA KEGG: 00130+1.14.99.60 Ubiquinone and other terpenoid-quinone biosynthesis 1 LLUN010266-PA Reactome: R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 24 LLUN011179-PA;LLUN006353-PA;LLUN000039-PA;LLUN011766-PA;LLUN004100-PA;LLUN009062-PA;LLUN003553-PA;LLUN011046-PA;LLUN002554-PA;LLUN009963-PA;LLUN002581-PA;LLUN003209-PA;LLUN007825-PA;LLUN003554-PA;LLUN008763-PA;LLUN006723-PA;LLUN008923-PA;LLUN011263-PA;LLUN001322-PA;LLUN002707-PA;LLUN002475-PA;LLUN001652-PA;LLUN011230-PA;LLUN003240-PA MetaCyc: PWY-5921 Glutaminyl-trnagln biosynthesis via transamidation 1 LLUN009510-PA Reactome: R-HSA-9018519 Estrogen-dependent gene expression 18 LLUN000521-PA;LLUN009178-PA;LLUN001676-PA;LLUN001290-PA;LLUN004016-PA;LLUN009496-PA;LLUN011861-PA;LLUN005309-PA;LLUN009498-PA;LLUN001654-PA;LLUN006269-PA;LLUN009871-PA;LLUN010444-PA;LLUN005720-PA;LLUN008644-PA;LLUN009676-PA;LLUN009497-PA;LLUN007911-PA Reactome: R-HSA-8941333 RUNX2 regulates genes involved in differentiation of myeloid cells 3 LLUN009498-PA;LLUN009496-PA;LLUN009497-PA KEGG: 00900+2.2.1.7 Terpenoid backbone biosynthesis 4 LLUN011427-PA;LLUN000032-PA;LLUN000747-PA;LLUN000909-PA Reactome: R-HSA-71403 Citric acid cycle (TCA cycle) 29 LLUN011264-PA;LLUN011761-PA;LLUN006149-PA;LLUN000255-PA;LLUN013118-PA;LLUN008350-PA;LLUN000601-PA;LLUN002372-PA;LLUN009867-PA;LLUN000261-PA;LLUN010033-PA;LLUN006602-PA;LLUN000260-PA;LLUN005021-PA;LLUN008347-PA;LLUN000889-PA;LLUN012634-PA;LLUN008348-PA;LLUN002997-PA;LLUN011983-PA;LLUN011041-PA;LLUN012663-PA;LLUN000046-PA;LLUN010962-PA;LLUN000029-PA;LLUN003300-PA;LLUN000259-PA;LLUN000276-PA;LLUN012407-PA KEGG: 00052+2.7.7.9 Galactose metabolism 1 LLUN009234-PA Reactome: R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 3 LLUN008644-PA;LLUN002369-PA;LLUN010444-PA Reactome: R-HSA-426048 Arachidonate production from DAG 2 LLUN003138-PA;LLUN010812-PA Reactome: R-HSA-8851708 Signaling by FGFR2 IIIa TM 9 LLUN000521-PA;LLUN009178-PA;LLUN001676-PA;LLUN009131-PA;LLUN009871-PA;LLUN001290-PA;LLUN011861-PA;LLUN007911-PA;LLUN001654-PA Reactome: R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 13 LLUN011163-PA;LLUN010115-PA;LLUN000563-PA;LLUN000692-PA;LLUN007180-PA;LLUN011570-PA;LLUN008476-PA;LLUN012819-PA;LLUN012973-PA;LLUN010205-PA;LLUN003498-PA;LLUN012021-PA;LLUN011433-PA Reactome: R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 2 LLUN002498-PA;LLUN012190-PA Reactome: R-HSA-1614603 Cysteine formation from homocysteine 6 LLUN006518-PA;LLUN000669-PA;LLUN000310-PA;LLUN012949-PA;LLUN000230-PA;LLUN000541-PA Reactome: R-HSA-2214320 Anchoring fibril formation 1 LLUN004092-PA Reactome: R-HSA-163560 Triglyceride catabolism 10 LLUN000668-PA;LLUN002624-PA;LLUN001696-PA;LLUN010207-PA;LLUN004425-PA;LLUN007584-PA;LLUN003895-PA;LLUN006053-PA;LLUN002098-PA;LLUN006055-PA Reactome: R-HSA-983231 Factors involved in megakaryocyte development and platelet production 13 LLUN001856-PA;LLUN008662-PA;LLUN010964-PA;LLUN001652-PA;LLUN006122-PA;LLUN005622-PA;LLUN011616-PA;LLUN009162-PA;LLUN005623-PA;LLUN009701-PA;LLUN001307-PA;LLUN001855-PA;LLUN006001-PA Reactome: R-HSA-380259 Loss of Nlp from mitotic centrosomes 3 LLUN002475-PA;LLUN009115-PA;LLUN011046-PA KEGG: 00430+2.7.2.1 Taurine and hypotaurine metabolism 2 LLUN007189-PA;LLUN009622-PA MetaCyc: PWY-7802 N-end rule pathway II (prokaryotic) 1 LLUN006394-PA KEGG: 00130+1.17.4.4 Ubiquinone and other terpenoid-quinone biosynthesis 1 LLUN001642-PA Reactome: R-HSA-8986944 Transcriptional Regulation by MECP2 2 LLUN005309-PA;LLUN009676-PA KEGG: 00280+2.3.1.16 Valine, leucine and isoleucine degradation 1 LLUN000585-PA Reactome: R-HSA-982772 Growth hormone receptor signaling 2 LLUN002516-PA;LLUN005622-PA Reactome: R-HSA-75955 RNA Polymerase II Transcription Elongation 30 LLUN011861-PA;LLUN002265-PA;LLUN009747-PA;LLUN002995-PA;LLUN001654-PA;LLUN001290-PA;LLUN005747-PA;LLUN003321-PA;LLUN011978-PA;LLUN010911-PA;LLUN009178-PA;LLUN008737-PA;LLUN001676-PA;LLUN012633-PA;LLUN007798-PA;LLUN004269-PA;LLUN008353-PA;LLUN000521-PA;LLUN007911-PA;LLUN011260-PA;LLUN001565-PA;LLUN004270-PA;LLUN009871-PA;LLUN002218-PA;LLUN008120-PA;LLUN009648-PA;LLUN011586-PA;LLUN001301-PA;LLUN012654-PA;LLUN010602-PA KEGG: 00770+6.3.2.5 Pantothenate and CoA biosynthesis 2 LLUN010650-PA;LLUN000524-PA KEGG: 00350+1.14.16.2 Tyrosine metabolism 1 LLUN000709-PA KEGG: 00520+5.4.2.10 Amino sugar and nucleotide sugar metabolism 5 LLUN004184-PA;LLUN009369-PA;LLUN000282-PA;LLUN000917-PA;LLUN009017-PA MetaCyc: PWY-7902 Glucosylglycerol biosynthesis 1 LLUN008432-PA MetaCyc: PWY-6661 4-hydroxy-2(1H)-quinolone biosynthesis 2 LLUN012019-PA;LLUN000681-PA Reactome: R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 31 LLUN010357-PA;LLUN010205-PA;LLUN008475-PA;LLUN003498-PA;LLUN008199-PA;LLUN003321-PA;LLUN011433-PA;LLUN000443-PA;LLUN000554-PA;LLUN012819-PA;LLUN005474-PA;LLUN005672-PA;LLUN000692-PA;LLUN005530-PA;LLUN007496-PA;LLUN011570-PA;LLUN008476-PA;LLUN010115-PA;LLUN007987-PA;LLUN000563-PA;LLUN007705-PA;LLUN008198-PA;LLUN012021-PA;LLUN008863-PA;LLUN008159-PA;LLUN012973-PA;LLUN004030-PA;LLUN007180-PA;LLUN011163-PA;LLUN008120-PA;LLUN003047-PA KEGG: 00520+3.5.99.6 Amino sugar and nucleotide sugar metabolism 2 LLUN004963-PA;LLUN007276-PA MetaCyc: PWY-7378 Aminopropanol phosphate biosynthesis II 1 LLUN000528-PA KEGG: 00350+3.7.1.2 Tyrosine metabolism 1 LLUN005637-PA KEGG: 00010+5.1.3.3 Glycolysis / Gluconeogenesis 2 LLUN001157-PA;LLUN005832-PA MetaCyc: PWY-7035 (9Z)-tricosene biosynthesis 18 LLUN011810-PA;LLUN005813-PA;LLUN003913-PA;LLUN008915-PA;LLUN002534-PA;LLUN011428-PA;LLUN001587-PA;LLUN001585-PA;LLUN003202-PA;LLUN001586-PA;LLUN009068-PA;LLUN002535-PA;LLUN004697-PA;LLUN003366-PA;LLUN004698-PA;LLUN003915-PA;LLUN011712-PA;LLUN000999-PA MetaCyc: PWY-801 Homocysteine and cysteine interconversion 2 LLUN000310-PA;LLUN000541-PA Reactome: R-HSA-5576886 Phase 4 - resting membrane potential 4 LLUN003416-PA;LLUN006005-PA;LLUN002378-PA;LLUN009439-PA Reactome: R-HSA-1660662 Glycosphingolipid metabolism 15 LLUN012575-PA;LLUN008090-PA;LLUN010383-PA;LLUN002778-PA;LLUN001270-PA;LLUN009341-PA;LLUN003183-PA;LLUN004238-PA;LLUN006288-PA;LLUN006286-PA;LLUN009763-PA;LLUN001743-PA;LLUN005178-PA;LLUN006287-PA;LLUN006511-PA KEGG: 00010+1.1.1.1 Glycolysis / Gluconeogenesis 1 LLUN012888-PA MetaCyc: PWY-7179 Purine deoxyribonucleosides degradation I 2 LLUN000578-PA;LLUN004537-PA Reactome: R-HSA-186763 Downstream signal transduction 1 LLUN007325-PA MetaCyc: PWYG-321 4 LLUN003811-PA;LLUN000176-PA;LLUN005169-PA;LLUN000184-PA Reactome: R-HSA-3371599 Defective HLCS causes multiple carboxylase deficiency 5 LLUN000112-PA;LLUN007441-PA;LLUN001217-PA;LLUN000113-PA;LLUN008045-PA KEGG: 00970+6.1.1.11 Aminoacyl-tRNA biosynthesis 4 LLUN008398-PA;LLUN007121-PA;LLUN009298-PA;LLUN013037-PA MetaCyc: PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian) 1 LLUN009162-PA Reactome: R-HSA-75105 Fatty acyl-CoA biosynthesis 22 LLUN003826-PA;LLUN005809-PA;LLUN009379-PA;LLUN004448-PA;LLUN011270-PA;LLUN007878-PA;LLUN005445-PA;LLUN000497-PA;LLUN011164-PA;LLUN000495-PA;LLUN009827-PA;LLUN003046-PA;LLUN005276-PA;LLUN012922-PA;LLUN010722-PA;LLUN005277-PA;LLUN004876-PA;LLUN002906-PA;LLUN009575-PA;LLUN011937-PA;LLUN009868-PA;LLUN010978-PA MetaCyc: PWY-6113 Superpathway of mycolate biosynthesis 4 LLUN005169-PA;LLUN000184-PA;LLUN000176-PA;LLUN003811-PA KEGG: 00520+5.4.2.8 Amino sugar and nucleotide sugar metabolism 1 LLUN007218-PA KEGG: 00500+5.3.1.9 Starch and sucrose metabolism 1 LLUN000137-PA MetaCyc: PWY-5913 Partial TCA cycle (obligate autotrophs) 17 LLUN000261-PA;LLUN005021-PA;LLUN012993-PA;LLUN012634-PA;LLUN012438-PA;LLUN003300-PA;LLUN000276-PA;LLUN012407-PA;LLUN011264-PA;LLUN009219-PA;LLUN007879-PA;LLUN000255-PA;LLUN007878-PA;LLUN000543-PA;LLUN007880-PA;LLUN008350-PA;LLUN009867-PA Reactome: R-HSA-6793080 rRNA modification in the mitochondrion 3 LLUN008743-PA;LLUN000269-PA;LLUN000047-PA Reactome: R-HSA-500753 Pyrimidine biosynthesis 5 LLUN008467-PA;LLUN006557-PA;LLUN013209-PA;LLUN000087-PA;LLUN007066-PA Reactome: R-HSA-5083635 Defective B3GALTL causes Peters-plus syndrome (PpS) 14 LLUN004503-PA;LLUN003505-PA;LLUN005564-PA;LLUN001391-PA;LLUN003200-PA;LLUN004313-PA;LLUN008322-PA;LLUN008626-PA;LLUN004632-PA;LLUN001369-PA;LLUN012955-PA;LLUN004801-PA;LLUN003060-PA;LLUN011341-PA Reactome: R-HSA-8851680 Butyrophilin (BTN) family interactions 1 LLUN009431-PA KEGG: 00010+5.4.2.11 Glycolysis / Gluconeogenesis 2 LLUN008352-PA;LLUN010054-PA Reactome: R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 7 LLUN009365-PA;LLUN001734-PA;LLUN006957-PA;LLUN002059-PA;LLUN005975-PA;LLUN004817-PA;LLUN000286-PA Reactome: R-HSA-392517 Rap1 signalling 1 LLUN000812-PA MetaCyc: PWY-7728 (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase) 2 LLUN009068-PA;LLUN011810-PA Reactome: R-HSA-176187 Activation of ATR in response to replication stress 19 LLUN008154-PA;LLUN007960-PA;LLUN004578-PA;LLUN004644-PA;LLUN007180-PA;LLUN012973-PA;LLUN008160-PA;LLUN012021-PA;LLUN004645-PA;LLUN009292-PA;LLUN010115-PA;LLUN008889-PA;LLUN008083-PA;LLUN005265-PA;LLUN011570-PA;LLUN008476-PA;LLUN007051-PA;LLUN008146-PA;LLUN008245-PA Reactome: R-HSA-419771 Opsins 3 LLUN007397-PA;LLUN004497-PA;LLUN004498-PA KEGG: 00500+3.2.1.93 Starch and sucrose metabolism 1 LLUN000290-PA KEGG: 00540+3.1.3.45 Lipopolysaccharide biosynthesis 1 LLUN000102-PA KEGG: 00230+4.6.1.2 Purine metabolism 5 LLUN001108-PA;LLUN009287-PA;LLUN005722-PA;LLUN005887-PA;LLUN003740-PA MetaCyc: PWY-6945 Cholesterol degradation to androstenedione I (cholesterol oxidase) 5 LLUN000586-PA;LLUN008953-PA;LLUN007706-PA;LLUN000585-PA;LLUN011561-PA Reactome: R-HSA-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 4 LLUN011607-PA;LLUN008821-PA;LLUN005856-PA;LLUN006063-PA Reactome: R-HSA-2022854 Keratan sulfate biosynthesis 4 LLUN013083-PA;LLUN006661-PA;LLUN007516-PA;LLUN008394-PA Reactome: R-HSA-3656237 Defective EXT2 causes exostoses 2 2 LLUN002060-PA;LLUN004191-PA Reactome: R-HSA-77595 Processing of Intronless Pre-mRNAs 6 LLUN004892-PA;LLUN009131-PA;LLUN012404-PA;LLUN000821-PA;LLUN003699-PA;LLUN006586-PA KEGG: 00540+2.5.1.55 Lipopolysaccharide biosynthesis 3 LLUN012135-PA;LLUN012864-PA;LLUN000339-PA MetaCyc: PWY-6281 L-selenocysteine biosynthesis II (archaea and eukaryotes) 5 LLUN008398-PA;LLUN008878-PA;LLUN009298-PA;LLUN013037-PA;LLUN007121-PA MetaCyc: PWY-7560 Methylerythritol phosphate pathway II 7 LLUN000321-PA;LLUN000032-PA;LLUN011427-PA;LLUN000174-PA;LLUN000747-PA;LLUN000050-PA;LLUN000909-PA Reactome: R-HSA-163754 Insulin effects increased synthesis of Xylulose-5-Phosphate 4 LLUN010125-PA;LLUN000057-PA;LLUN006322-PA;LLUN000222-PA Reactome: R-HSA-181429 Serotonin Neurotransmitter Release Cycle 3 LLUN000986-PA;LLUN011055-PA;LLUN008631-PA Reactome: R-HSA-428930 Thromboxane signalling through TP receptor 2 LLUN009047-PA;LLUN009048-PA MetaCyc: PWY-6080 4-ethylphenol degradation (anaerobic) 1 LLUN000585-PA MetaCyc: PWY-5101 L-isoleucine biosynthesis II 2 LLUN000044-PA;LLUN000551-PA MetaCyc: PWY-6854 Ethylene biosynthesis III (microbes) 9 LLUN001208-PA;LLUN011977-PA;LLUN005394-PA;LLUN008940-PA;LLUN011898-PA;LLUN010426-PA;LLUN010402-PA;LLUN005708-PA;LLUN005006-PA MetaCyc: PWY-5137 Fatty acid beta-oxidation III (unsaturated, odd number) 1 LLUN000586-PA Reactome: R-HSA-2206282 MPS IIIB - Sanfilippo syndrome B 1 LLUN011339-PA MetaCyc: PWY-7216 (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered) 4 LLUN011561-PA;LLUN007706-PA;LLUN000586-PA;LLUN008953-PA MetaCyc: PWY-7416 Phospholipid remodeling (phosphatidylcholine, yeast) 7 LLUN003536-PA;LLUN001370-PA;LLUN003919-PA;LLUN008242-PA;LLUN000563-PA;LLUN008580-PA;LLUN001410-PA MetaCyc: PWY-5892 Menaquinol-12 biosynthesis 2 LLUN007379-PA;LLUN000579-PA MetaCyc: PWY-6696 Oxalate degradation III 1 LLUN009876-PA KEGG: 00230+2.4.2.1 Purine metabolism 1 LLUN000578-PA Reactome: R-HSA-379726 Mitochondrial tRNA aminoacylation 14 LLUN000150-PA;LLUN000232-PA;LLUN005993-PA;LLUN012936-PA;LLUN007278-PA;LLUN000051-PA;LLUN010324-PA;LLUN011099-PA;LLUN007623-PA;LLUN000526-PA;LLUN009588-PA;LLUN009306-PA;LLUN000676-PA;LLUN012047-PA KEGG: 00720+2.7.9.2 Carbon fixation pathways in prokaryotes 1 LLUN012863-PA Reactome: R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 35 LLUN005440-PA;LLUN003501-PA;LLUN012548-PA;LLUN008960-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN002998-PA;LLUN006267-PA;LLUN002054-PA;LLUN009994-PA;LLUN001565-PA;LLUN004861-PA;LLUN000089-PA;LLUN009496-PA;LLUN004794-PA;LLUN005610-PA;LLUN008477-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN006525-PA;LLUN010602-PA;LLUN009497-PA;LLUN008342-PA;LLUN009980-PA;LLUN006627-PA;LLUN002894-PA;LLUN005530-PA;LLUN004508-PA;LLUN005593-PA;LLUN009498-PA;LLUN003629-PA;LLUN005030-PA;LLUN013272-PA Reactome: R-HSA-5578775 Ion homeostasis 8 LLUN002727-PA;LLUN005561-PA;LLUN004972-PA;LLUN006368-PA;LLUN000381-PA;LLUN001707-PA;LLUN011839-PA;LLUN005562-PA MetaCyc: PWY-7337 10-cis-heptadecenoyl-CoA degradation (yeast) 2 LLUN000585-PA;LLUN000586-PA KEGG: 00010+1.2.4.1 Glycolysis / Gluconeogenesis 1 LLUN000032-PA Reactome: R-HSA-5683371 Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7) 2 LLUN011116-PA;LLUN010642-PA MetaCyc: PWY-7218 Photosynthetic 3-hydroxybutanoate biosynthesis (engineered) 4 LLUN012182-PA;LLUN007408-PA;LLUN013179-PA;LLUN000530-PA Reactome: R-HSA-936837 Ion transport by P-type ATPases 38 LLUN007137-PA;LLUN007452-PA;LLUN007097-PA;LLUN007320-PA;LLUN005606-PA;LLUN000918-PA;LLUN006806-PA;LLUN007318-PA;LLUN004695-PA;LLUN006235-PA;LLUN001274-PA;LLUN007096-PA;LLUN009798-PA;LLUN008969-PA;LLUN011839-PA;LLUN000420-PA;LLUN002348-PA;LLUN007368-PA;LLUN002347-PA;LLUN012617-PA;LLUN001806-PA;LLUN011957-PA;LLUN000767-PA;LLUN008195-PA;LLUN006545-PA;LLUN001807-PA;LLUN011524-PA;LLUN002912-PA;LLUN006236-PA;LLUN002913-PA;LLUN000059-PA;LLUN011381-PA;LLUN012380-PA;LLUN013252-PA;LLUN001273-PA;LLUN011512-PA;LLUN000568-PA;LLUN000381-PA MetaCyc: PWY-5079 L-phenylalanine degradation III 1 LLUN012888-PA MetaCyc: PWY-6823 Molybdenum cofactor biosynthesis 2 LLUN010509-PA;LLUN011579-PA Reactome: R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 10 LLUN008449-PA;LLUN002885-PA;LLUN010670-PA;LLUN007070-PA;LLUN006122-PA;LLUN013020-PA;LLUN008450-PA;LLUN002516-PA;LLUN007009-PA;LLUN012891-PA KEGG: 00030+3.1.1.31 Pentose phosphate pathway 1 LLUN004963-PA MetaCyc: PWY-2201 Folate transformations I 9 LLUN005962-PA;LLUN000141-PA;LLUN006558-PA;LLUN000542-PA;LLUN000777-PA;LLUN010882-PA;LLUN011200-PA;LLUN000209-PA;LLUN011129-PA MetaCyc: PWY-5873 Ubiquinol-7 biosynthesis (eukaryotic) 3 LLUN000136-PA;LLUN003684-PA;LLUN010266-PA MetaCyc: PWY-5108 L-isoleucine biosynthesis V 2 LLUN001912-PA;LLUN000254-PA MetaCyc: PWY-7761 NAD salvage pathway II (PNC IV cycle) 1 LLUN010074-PA KEGG: 00620+2.7.9.2 Pyruvate metabolism 1 LLUN012863-PA KEGG: 00052+3.2.1.23 Galactose metabolism 4 LLUN000904-PA;LLUN001229-PA;LLUN000905-PA;LLUN010751-PA MetaCyc: PWY-7841 Neolacto-series glycosphingolipids biosynthesis 1 LLUN004238-PA MetaCyc: PWY-7884 Lipoprotein posttranslational modification 1 LLUN000051-PA Reactome: R-HSA-8963693 Aspartate and asparagine metabolism 2 LLUN007275-PA;LLUN003426-PA KEGG: 00860+1.3.3.3 Porphyrin and chlorophyll metabolism 2 LLUN000224-PA;LLUN012136-PA MetaCyc: PWY-7342 Superpathway of nicotine biosynthesis 2 LLUN000035-PA;LLUN000889-PA Reactome: R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 6 LLUN011605-PA;LLUN008924-PA;LLUN007305-PA;LLUN000871-PA;LLUN008304-PA;LLUN006592-PA KEGG: 00790+1.7.1.13 Folate biosynthesis 1 LLUN000167-PA Reactome: R-HSA-9664565 Signaling by ERBB2 KD Mutants 3 LLUN008416-PA;LLUN008205-PA;LLUN000021-PA KEGG: 00020+2.3.1.12 Citrate cycle (TCA cycle) 1 LLUN000030-PA KEGG: 00260+5.4.2.12 Glycine, serine and threonine metabolism 1 LLUN000530-PA KEGG: 00020+4.1.1.32 Citrate cycle (TCA cycle) 1 LLUN003283-PA KEGG: 04926+2.7.11.1 Relaxin signaling pathway 15 LLUN009259-PA;LLUN007496-PA;LLUN012841-PA;LLUN005145-PA;LLUN007485-PA;LLUN009503-PA;LLUN001111-PA;LLUN012849-PA;LLUN011312-PA;LLUN006440-PA;LLUN002957-PA;LLUN007666-PA;LLUN011988-PA;LLUN010447-PA;LLUN000510-PA Reactome: R-HSA-111459 Activation of caspases through apoptosome-mediated cleavage 6 LLUN006836-PA;LLUN003543-PA;LLUN003801-PA;LLUN011888-PA;LLUN006174-PA;LLUN011140-PA MetaCyc: PWY-6599 Guanine and guanosine salvage II 1 LLUN006332-PA KEGG: 00240+2.4.2.4 Pyrimidine metabolism 1 LLUN000064-PA Reactome: R-HSA-9027277 Erythropoietin activates Phospholipase C gamma (PLCG) 1 LLUN004409-PA MetaCyc: PWY-7274 D-cycloserine biosynthesis 1 LLUN000532-PA Reactome: R-HSA-4641258 Degradation of DVL 30 LLUN005530-PA;LLUN002894-PA;LLUN000089-PA;LLUN008477-PA;LLUN003629-PA;LLUN013272-PA;LLUN003215-PA;LLUN004706-PA;LLUN005030-PA;LLUN010012-PA;LLUN004794-PA;LLUN004508-PA;LLUN005593-PA;LLUN005610-PA;LLUN012548-PA;LLUN008960-PA;LLUN006525-PA;LLUN003501-PA;LLUN005440-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA;LLUN009994-PA;LLUN006627-PA;LLUN004861-PA;LLUN008342-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN002998-PA KEGG: 00630+1.17.1.9 Glyoxylate and dicarboxylate metabolism 1 LLUN009876-PA Reactome: R-HSA-69166 Removal of the Flap Intermediate 8 LLUN008476-PA;LLUN007180-PA;LLUN004948-PA;LLUN009996-PA;LLUN010178-PA;LLUN008802-PA;LLUN006991-PA;LLUN008719-PA Reactome: R-HSA-8957275 Post-translational protein phosphorylation 5 LLUN006087-PA;LLUN011465-PA;LLUN011466-PA;LLUN001691-PA;LLUN003870-PA Reactome: R-HSA-6794361 Neurexins and neuroligins 3 LLUN008044-PA;LLUN002146-PA;LLUN010175-PA KEGG: 00540+2.7.7.38 Lipopolysaccharide biosynthesis 1 LLUN013139-PA KEGG: 00380+1.13.11.11 Tryptophan metabolism 2 LLUN003223-PA;LLUN004105-PA MetaCyc: PWY-6507 4-deoxy-L-threo-hex-4-enopyranuronate degradation 1 LLUN009403-PA Reactome: R-HSA-8876493 InlA-mediated entry of Listeria monocytogenes into host cells 1 LLUN005530-PA Reactome: R-HSA-2129379 Molecules associated with elastic fibres 1 LLUN011961-PA MetaCyc: PWY-7654 (8E,10E)-dodeca-8,10-dienol biosynthesis 5 LLUN011561-PA;LLUN000585-PA;LLUN007706-PA;LLUN008953-PA;LLUN000586-PA MetaCyc: PWY-241 C4 photosynthetic carbon assimilation cycle, NADP-ME type 5 LLUN008096-PA;LLUN008095-PA;LLUN000543-PA;LLUN006407-PA;LLUN005628-PA Reactome: R-HSA-2500257 Resolution of Sister Chromatid Cohesion 23 LLUN011179-PA;LLUN006353-PA;LLUN000039-PA;LLUN009062-PA;LLUN003553-PA;LLUN004100-PA;LLUN011766-PA;LLUN003438-PA;LLUN009748-PA;LLUN007825-PA;LLUN011378-PA;LLUN003554-PA;LLUN009963-PA;LLUN003209-PA;LLUN004221-PA;LLUN002581-PA;LLUN010831-PA;LLUN001322-PA;LLUN002707-PA;LLUN006723-PA;LLUN008923-PA;LLUN003240-PA;LLUN002475-PA MetaCyc: PWY-7821 Tunicamycin biosynthesis 4 LLUN000110-PA;LLUN000322-PA;LLUN006214-PA;LLUN003890-PA KEGG: 00640+6.2.1.1 Propanoate metabolism 2 LLUN000254-PA;LLUN001912-PA KEGG: 00510+2.4.1.258 N-Glycan biosynthesis 1 LLUN003653-PA KEGG: 00240+2.7.4.9 Pyrimidine metabolism 2 LLUN006605-PA;LLUN005171-PA KEGG: 00240+6.3.4.2 Pyrimidine metabolism 1 LLUN000315-PA Reactome: R-HSA-196807 Nicotinate metabolism 4 LLUN009750-PA;LLUN008323-PA;LLUN009904-PA;LLUN000035-PA Reactome: R-HSA-112382 Formation of RNA Pol II elongation complex 31 LLUN007911-PA;LLUN011260-PA;LLUN001565-PA;LLUN008120-PA;LLUN009871-PA;LLUN009131-PA;LLUN002218-PA;LLUN004270-PA;LLUN010602-PA;LLUN001301-PA;LLUN012654-PA;LLUN011586-PA;LLUN009648-PA;LLUN002995-PA;LLUN001654-PA;LLUN009747-PA;LLUN002265-PA;LLUN011861-PA;LLUN011978-PA;LLUN003321-PA;LLUN001290-PA;LLUN005747-PA;LLUN001676-PA;LLUN012633-PA;LLUN008737-PA;LLUN009178-PA;LLUN010911-PA;LLUN000521-PA;LLUN004269-PA;LLUN007798-PA;LLUN008353-PA MetaCyc: PWY-4841 UDP-alpha-D-glucuronate biosynthesis (from myo-inositol) 1 LLUN004918-PA KEGG: 00240+1.17.4.1 Pyrimidine metabolism 2 LLUN008193-PA;LLUN001080-PA KEGG: 00010+4.2.1.11 Glycolysis / Gluconeogenesis 1 LLUN012182-PA MetaCyc: PWY-2941 L-lysine biosynthesis II 2 LLUN000049-PA;LLUN012256-PA Reactome: R-HSA-1614558 Degradation of cysteine and homocysteine 5 LLUN000669-PA;LLUN012949-PA;LLUN000541-PA;LLUN009534-PA;LLUN000310-PA KEGG: 00604+3.2.1.23 Glycosphingolipid biosynthesis - ganglio series 4 LLUN001229-PA;LLUN000904-PA;LLUN010751-PA;LLUN000905-PA KEGG: 04070+2.7.1.159 Phosphatidylinositol signaling system 1 LLUN009162-PA KEGG: 00830+1.1.1.1 Retinol metabolism 1 LLUN012888-PA KEGG: 00010+5.3.1.9 Glycolysis / Gluconeogenesis 1 LLUN000137-PA Reactome: R-HSA-1912408 Pre-NOTCH Transcription and Translation 6 LLUN005309-PA;LLUN003131-PA;LLUN009676-PA;LLUN008644-PA;LLUN010444-PA;LLUN002369-PA Reactome: R-HSA-5578998 Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) 2 LLUN002291-PA;LLUN011048-PA KEGG: 00650+1.3.5.4 Butanoate metabolism 1 LLUN000261-PA KEGG: 00280+1.8.1.4 Valine, leucine and isoleucine degradation 1 LLUN000029-PA Reactome: R-HSA-162588 Budding and maturation of HIV virion 6 LLUN007046-PA;LLUN010039-PA;LLUN005530-PA;LLUN002215-PA;LLUN005247-PA;LLUN013036-PA Reactome: R-HSA-2424491 DAP12 signaling 1 LLUN004409-PA MetaCyc: PWY-6703 Preq0 biosynthesis 2 LLUN012034-PA;LLUN005541-PA MetaCyc: PWY-6713 L-rhamnose degradation II 1 LLUN000572-PA KEGG: 00626+1.1.1.1 Naphthalene degradation 1 LLUN012888-PA Reactome: R-HSA-428543 Inactivation of CDC42 and RAC1 1 LLUN006122-PA Reactome: R-HSA-5218921 VEGFR2 mediated cell proliferation 3 LLUN007325-PA;LLUN004972-PA;LLUN007485-PA KEGG: 00520+2.7.7.13 Amino sugar and nucleotide sugar metabolism 1 LLUN000917-PA Reactome: R-HSA-216083 Integrin cell surface interactions 9 LLUN000422-PA;LLUN009271-PA;LLUN007802-PA;LLUN001519-PA;LLUN006651-PA;LLUN001518-PA;LLUN002361-PA;LLUN011942-PA;LLUN004092-PA KEGG: 00620+1.3.5.4 Pyruvate metabolism 1 LLUN000261-PA KEGG: 00040+5.3.1.17 Pentose and glucuronate interconversions 1 LLUN009403-PA MetaCyc: PWY-6891 Thiazole biosynthesis II (aerobic bacteria) 4 LLUN000747-PA;LLUN000032-PA;LLUN011427-PA;LLUN000909-PA KEGG: 00510+2.4.1.256 N-Glycan biosynthesis 1 LLUN009201-PA MetaCyc: PWY-7536 2-amino-3-hydroxycyclopent-2-enone biosynthesis 1 LLUN005927-PA KEGG: 00053+4.2.1.40 Ascorbate and aldarate metabolism 2 LLUN000920-PA;LLUN000921-PA Reactome: R-HSA-444257 RSK activation 2 LLUN007485-PA;LLUN002516-PA Reactome: R-HSA-373080 Class B/2 (Secretin family receptors) 24 LLUN012578-PA;LLUN005871-PA;LLUN009983-PA;LLUN002604-PA;LLUN012525-PA;LLUN001594-PA;LLUN009243-PA;LLUN010850-PA;LLUN004314-PA;LLUN009590-PA;LLUN001595-PA;LLUN001144-PA;LLUN001628-PA;LLUN003029-PA;LLUN001143-PA;LLUN013141-PA;LLUN005112-PA;LLUN005656-PA;LLUN004816-PA;LLUN002252-PA;LLUN001360-PA;LLUN007777-PA;LLUN001427-PA;LLUN009244-PA Reactome: R-HSA-2586552 Signaling by Leptin 1 LLUN005622-PA Reactome: R-HSA-432142 Platelet sensitization by LDL 1 LLUN011378-PA Reactome: R-HSA-9020702 Interleukin-1 signaling 31 LLUN000089-PA;LLUN002894-PA;LLUN005530-PA;LLUN004794-PA;LLUN004508-PA;LLUN005610-PA;LLUN005593-PA;LLUN003629-PA;LLUN008477-PA;LLUN003215-PA;LLUN010012-PA;LLUN005030-PA;LLUN004706-PA;LLUN013272-PA;LLUN006525-PA;LLUN005440-PA;LLUN003501-PA;LLUN012548-PA;LLUN008960-PA;LLUN010393-PA;LLUN011115-PA;LLUN012429-PA;LLUN008342-PA;LLUN002998-PA;LLUN002054-PA;LLUN009980-PA;LLUN006267-PA;LLUN006111-PA;LLUN009994-PA;LLUN004861-PA;LLUN006627-PA MetaCyc: PWY-5870 Ubiquinol-8 biosynthesis (eukaryotic) 3 LLUN010266-PA;LLUN000136-PA;LLUN003684-PA MetaCyc: PWY-4081 Glutathione-peroxide redox reactions 1 LLUN000660-PA KEGG: 00030+5.4.2.7 Pentose phosphate pathway 1 LLUN000063-PA MetaCyc: PWY-7661 Protein N-glycosylation (Haloferax volcanii) 1 LLUN006904-PA KEGG: 00900+4.1.1.33 Terpenoid backbone biosynthesis 1 LLUN009836-PA MetaCyc: PWY-8040 Ansatrienin biosynthesis 3 LLUN000131-PA;LLUN005700-PA;LLUN000915-PA KEGG: 00230+4.3.2.2 Purine metabolism 1 LLUN002429-PA Reactome: R-HSA-5656121 Translesion synthesis by POLI 7 LLUN009996-PA;LLUN001634-PA;LLUN012973-PA;LLUN011570-PA;LLUN008476-PA;LLUN007180-PA;LLUN005530-PA KEGG: 00720+1.3.5.1 Carbon fixation pathways in prokaryotes 4 LLUN012663-PA;LLUN000260-PA;LLUN011041-PA;LLUN008348-PA KEGG: 00330+3.5.1.96 Arginine and proline metabolism 1 LLUN012455-PA MetaCyc: PWY-8086 (S)-lactate fermentation to propanoate, acetate and hydrogen 10 LLUN009622-PA;LLUN007189-PA;LLUN000276-PA;LLUN009867-PA;LLUN000255-PA;LLUN005021-PA;LLUN000261-PA;LLUN012634-PA;LLUN000223-PA;LLUN012438-PA Reactome: R-HSA-446199 Synthesis of Dolichyl-phosphate 3 LLUN012075-PA;LLUN009836-PA;LLUN000175-PA Reactome: R-HSA-9615710 Late endosomal microautophagy 7 LLUN005247-PA;LLUN013036-PA;LLUN012758-PA;LLUN007046-PA;LLUN000749-PA;LLUN002215-PA;LLUN005530-PA MetaCyc: PWY-7791 UMP biosynthesis III 5 LLUN004225-PA;LLUN009630-PA;LLUN000087-PA;LLUN006557-PA;LLUN000049-PA MetaCyc: PWY-6308 L-cysteine biosynthesis II (tRNA-dependent) 3 LLUN002711-PA;LLUN012092-PA;LLUN012108-PA Reactome: R-HSA-918233 TRAF3-dependent IRF activation pathway 3 LLUN010444-PA;LLUN004172-PA;LLUN008644-PA Reactome: R-HSA-422356 Regulation of insulin secretion 1 LLUN004972-PA KEGG: 00020+1.3.5.1 Citrate cycle (TCA cycle) 4 LLUN012663-PA;LLUN011041-PA;LLUN000260-PA;LLUN008348-PA KEGG: 00620+1.1.5.4 Pyruvate metabolism 1 LLUN001228-PA Reactome: R-HSA-433137 Sodium-coupled sulphate, di- and tri-carboxylate transporters 2 LLUN004822-PA;LLUN000478-PA Reactome: R-HSA-3371511 HSF1 activation 2 LLUN007180-PA;LLUN008476-PA KEGG: 00562+5.5.1.4 Inositol phosphate metabolism 1 LLUN006316-PA MetaCyc: PWY-6788 Cellulose degradation II (fungi) 3 LLUN001401-PA;LLUN001402-PA;LLUN011004-PA MetaCyc: PWY-7980 ATP biosynthesis 5 LLUN005731-PA;LLUN001187-PA;LLUN000558-PA;LLUN006324-PA;LLUN002012-PA KEGG: 00920+2.5.1.48 Sulfur metabolism 1 LLUN000541-PA KEGG: 00071+4.2.1.17+1.1.1.35 Fatty acid degradation 4 LLUN007706-PA;LLUN008953-PA;LLUN000586-PA;LLUN011561-PA MetaCyc: PWY-6611 Adenine and adenosine salvage V 2 LLUN000578-PA;LLUN004537-PA KEGG: 00643+1.13.11.5 Styrene degradation 3 LLUN001356-PA;LLUN001355-PA;LLUN001354-PA KEGG: 00480+1.1.1.42 Glutathione metabolism 1 LLUN012407-PA Reactome: R-HSA-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors 1 LLUN011732-PA Reactome: R-HSA-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production 2 LLUN010444-PA;LLUN008644-PA KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35 Fatty acid degradation 2 LLUN011561-PA;LLUN000586-PA KEGG: 00071+6.2.1.20 Fatty acid degradation 1 LLUN000161-PA MetaCyc: PWY-3881 Mannitol biosynthesis 1 LLUN011806-PA KEGG: 00310+4.2.1.17+1.1.1.35 Lysine degradation 4 LLUN011561-PA;LLUN008953-PA;LLUN000586-PA;LLUN007706-PA Reactome: R-HSA-5689896 Ovarian tumor domain proteases 2 LLUN012323-PA;LLUN005530-PA KEGG: 00562+3.1.4.11 Inositol phosphate metabolism 3 LLUN008499-PA;LLUN004409-PA;LLUN007371-PA MetaCyc: PWY-6122 5-aminoimidazole ribonucleotide biosynthesis II 3 LLUN010077-PA;LLUN006933-PA;LLUN006932-PA KEGG: 04150+2.7.11.24 mTOR signaling pathway 2 LLUN002516-PA;LLUN007704-PA KEGG: 00903+4.2.1.17 Limonene and pinene degradation 4 LLUN007706-PA;LLUN000586-PA;LLUN008953-PA;LLUN011561-PA MetaCyc: PWY-7727 Docosahexaenoate biosynthesis IV (4-desaturase, mammals) 2 LLUN009068-PA;LLUN011810-PA MetaCyc: PWY-7238 Sucrose biosynthesis II 9 LLUN000667-PA;LLUN004023-PA;LLUN000671-PA;LLUN000295-PA;LLUN000137-PA;LLUN009234-PA;LLUN001762-PA;LLUN009874-PA;LLUN010451-PA Reactome: R-HSA-8949664 Processing of SMDT1 6 LLUN006527-PA;LLUN004174-PA;LLUN000280-PA;LLUN011474-PA;LLUN005826-PA;LLUN009652-PA KEGG: 00680+3.1.3.3 Methane metabolism 2 LLUN000062-PA;LLUN006711-PA Reactome: R-HSA-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 1 LLUN000759-PA Reactome: R-HSA-69205 G1/S-Specific Transcription 9 LLUN000163-PA;LLUN001786-PA;LLUN010665-PA;LLUN008245-PA;LLUN008083-PA;LLUN008889-PA;LLUN009996-PA;LLUN008485-PA;LLUN004788-PA KEGG: 05165+2.7.11.1 Human papillomavirus infection 15 LLUN002957-PA;LLUN006440-PA;LLUN001111-PA;LLUN011312-PA;LLUN012849-PA;LLUN009503-PA;LLUN007485-PA;LLUN012841-PA;LLUN007496-PA;LLUN005145-PA;LLUN009259-PA;LLUN000510-PA;LLUN010447-PA;LLUN011988-PA;LLUN007666-PA Reactome: R-HSA-1237044 Erythrocytes take up carbon dioxide and release oxygen 2 LLUN009270-PA;LLUN000208-PA KEGG: 00061+4.2.1.59 Fatty acid biosynthesis 1 LLUN000176-PA MetaCyc: PWY-5172 Acetyl-coa biosynthesis III (from citrate) 1 LLUN007878-PA Reactome: R-HSA-9609523 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 5 LLUN008564-PA;LLUN005263-PA;LLUN009459-PA;LLUN007012-PA;LLUN001256-PA Reactome: R-HSA-389887 Beta-oxidation of pristanoyl-CoA 1 LLUN000759-PA MetaCyc: PWY-7184 Pyrimidine deoxyribonucleotides de novo biosynthesis I 15 LLUN011985-PA;LLUN008193-PA;LLUN012628-PA;LLUN003890-PA;LLUN006605-PA;LLUN006214-PA;LLUN000110-PA;LLUN000213-PA;LLUN012527-PA;LLUN001080-PA;LLUN010665-PA;LLUN005171-PA;LLUN000163-PA;LLUN006247-PA;LLUN003082-PA KEGG: 00380+4.1.1.105 Tryptophan metabolism 1 LLUN000568-PA MetaCyc: PWY-6554 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3) 1 LLUN009162-PA KEGG: 00591+3.1.1.4 Linoleic acid metabolism 7 LLUN001410-PA;LLUN000563-PA;LLUN008580-PA;LLUN008242-PA;LLUN003919-PA;LLUN003536-PA;LLUN001370-PA KEGG: 00910+4.2.1.1 Nitrogen metabolism 4 LLUN005628-PA;LLUN006407-PA;LLUN008096-PA;LLUN008095-PA Reactome: R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 29 LLUN002894-PA;LLUN000089-PA;LLUN003629-PA;LLUN008477-PA;LLUN013272-PA;LLUN005030-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN004794-PA;LLUN004508-PA;LLUN005593-PA;LLUN005610-PA;LLUN012548-PA;LLUN008960-PA;LLUN006525-PA;LLUN003501-PA;LLUN005440-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA;LLUN004861-PA;LLUN009994-PA;LLUN006627-PA;LLUN008342-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN002998-PA MetaCyc: PWY-7401 Crotonate fermentation (to acetate and cyclohexane carboxylate) 4 LLUN011561-PA;LLUN008953-PA;LLUN000586-PA;LLUN007706-PA MetaCyc: PWY-5049 Rosmarinic acid biosynthesis II 1 LLUN000709-PA KEGG: 00730+2.5.1.3 Thiamine metabolism 1 LLUN000288-PA Reactome: R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 1 LLUN005530-PA KEGG: 00564+2.7.7.41 Glycerophospholipid metabolism 1 LLUN009855-PA KEGG: 04151+2.7.1.153 PI3K-Akt signaling pathway 1 LLUN006224-PA KEGG: 00760+2.7.1.23 Nicotinate and nicotinamide metabolism 1 LLUN008323-PA Reactome: R-HSA-196780 Biotin transport and metabolism 9 LLUN008045-PA;LLUN010077-PA;LLUN001217-PA;LLUN005463-PA;LLUN007441-PA;LLUN000112-PA;LLUN000113-PA;LLUN011458-PA;LLUN000178-PA KEGG: 00520+2.7.1.6 Amino sugar and nucleotide sugar metabolism 2 LLUN003916-PA;LLUN004037-PA MetaCyc: PWY-5857 Ubiquinol-10 biosynthesis (prokaryotic) 4 LLUN000136-PA;LLUN003684-PA;LLUN000584-PA;LLUN010266-PA Reactome: R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 2 LLUN011839-PA;LLUN008044-PA MetaCyc: PWY-5789 3-hydroxypropanoate/4-hydroxybutanate cycle 9 LLUN008953-PA;LLUN000586-PA;LLUN006407-PA;LLUN005628-PA;LLUN008096-PA;LLUN008095-PA;LLUN007706-PA;LLUN011561-PA;LLUN000178-PA Reactome: R-HSA-6807878 COPI-mediated anterograde transport 35 LLUN008300-PA;LLUN000039-PA;LLUN011179-PA;LLUN003553-PA;LLUN004100-PA;LLUN011766-PA;LLUN011046-PA;LLUN003728-PA;LLUN002147-PA;LLUN009963-PA;LLUN007825-PA;LLUN003718-PA;LLUN009459-PA;LLUN008923-PA;LLUN008763-PA;LLUN002935-PA;LLUN006756-PA;LLUN009885-PA;LLUN001322-PA;LLUN002707-PA;LLUN002699-PA;LLUN001652-PA;LLUN003240-PA;LLUN006353-PA;LLUN009062-PA;LLUN002581-PA;LLUN003209-PA;LLUN011584-PA;LLUN003554-PA;LLUN005991-PA;LLUN006723-PA;LLUN011966-PA;LLUN012028-PA;LLUN008668-PA;LLUN010728-PA Reactome: R-HSA-162791 Attachment of GPI anchor to uPAR 3 LLUN007335-PA;LLUN007007-PA;LLUN010195-PA Reactome: R-HSA-1482922 Acyl chain remodelling of PI 3 LLUN008580-PA;LLUN001410-PA;LLUN003536-PA Reactome: R-HSA-5632928 Defective Mismatch Repair Associated With MSH2 1 LLUN000324-PA KEGG: 00220+2.7.2.8 Arginine biosynthesis 1 LLUN000545-PA Reactome: R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 3 LLUN000554-PA;LLUN000443-PA;LLUN002516-PA MetaCyc: PWY-5667 CDP-diacylglycerol biosynthesis I 4 LLUN000308-PA;LLUN009855-PA;LLUN008432-PA;LLUN008689-PA Reactome: R-HSA-9665245 Resistance of ERBB2 KD mutants to tesevatinib 2 LLUN008205-PA;LLUN008416-PA KEGG: 00900+2.7.7.60 Terpenoid backbone biosynthesis 1 LLUN000321-PA KEGG: 00240+3.5.4.12 Pyrimidine metabolism 1 LLUN011011-PA Reactome: R-HSA-111464 SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes 7 LLUN006836-PA;LLUN003543-PA;LLUN003801-PA;LLUN001057-PA;LLUN006174-PA;LLUN011888-PA;LLUN011140-PA KEGG: 00480+2.3.2.2+3.4.19.13 Glutathione metabolism 3 LLUN000193-PA;LLUN000741-PA;LLUN001088-PA MetaCyc: PWY-7117 C4 photosynthetic carbon assimilation cycle, PEPCK type 6 LLUN008096-PA;LLUN008095-PA;LLUN006407-PA;LLUN000543-PA;LLUN009219-PA;LLUN005628-PA KEGG: 00531+3.2.1.23 Glycosaminoglycan degradation 4 LLUN001229-PA;LLUN000904-PA;LLUN000905-PA;LLUN010751-PA Reactome: R-HSA-6798695 Neutrophil degranulation 65 LLUN008395-PA;LLUN002054-PA;LLUN001010-PA;LLUN012146-PA;LLUN004112-PA;LLUN010519-PA;LLUN004049-PA;LLUN009909-PA;LLUN000805-PA;LLUN010751-PA;LLUN009646-PA;LLUN008139-PA;LLUN008475-PA;LLUN001020-PA;LLUN008234-PA;LLUN000137-PA;LLUN006286-PA;LLUN010957-PA;LLUN012848-PA;LLUN011097-PA;LLUN005991-PA;LLUN000905-PA;LLUN010451-PA;LLUN006525-PA;LLUN006148-PA;LLUN004023-PA;LLUN005137-PA;LLUN001229-PA;LLUN006176-PA;LLUN012000-PA;LLUN000578-PA;LLUN011115-PA;LLUN000036-PA;LLUN001796-PA;LLUN008935-PA;LLUN005440-PA;LLUN009875-PA;LLUN002749-PA;LLUN002155-PA;LLUN001889-PA;LLUN011442-PA;LLUN001233-PA;LLUN004794-PA;LLUN008477-PA;LLUN004942-PA;LLUN013202-PA;LLUN001019-PA;LLUN002757-PA;LLUN005138-PA;LLUN009089-PA;LLUN004537-PA;LLUN012575-PA;LLUN006287-PA;LLUN012460-PA;LLUN001942-PA;LLUN004553-PA;LLUN007852-PA;LLUN006056-PA;LLUN010537-PA;LLUN010175-PA;LLUN007878-PA;LLUN012652-PA;LLUN005178-PA;LLUN000065-PA;LLUN006288-PA Reactome: R-HSA-159740 Gamma-carboxylation of protein precursors 1 LLUN009130-PA MetaCyc: PWY-7032 Alkane biosynthesis I 1 LLUN000161-PA MetaCyc: PWY-5839 Menaquinol-7 biosynthesis 2 LLUN000579-PA;LLUN007379-PA MetaCyc: PWY-7112 4-hydroxy-2-nonenal detoxification 5 LLUN008487-PA;LLUN000193-PA;LLUN000741-PA;LLUN008086-PA;LLUN001088-PA KEGG: 00980+2.5.1.18 Metabolism of xenobiotics by cytochrome P450 2 LLUN008086-PA;LLUN008487-PA MetaCyc: PWY-6433 Hydroxylated fatty acid biosynthesis (plants) 18 LLUN004697-PA;LLUN003366-PA;LLUN004698-PA;LLUN003915-PA;LLUN002535-PA;LLUN011712-PA;LLUN000999-PA;LLUN003913-PA;LLUN005813-PA;LLUN011810-PA;LLUN001585-PA;LLUN003202-PA;LLUN001586-PA;LLUN009068-PA;LLUN001587-PA;LLUN008915-PA;LLUN011428-PA;LLUN002534-PA Reactome: R-HSA-3295583 TRP channels 4 LLUN000955-PA;LLUN012928-PA;LLUN002249-PA;LLUN007904-PA KEGG: 00250+1.2.1.88 Alanine, aspartate and glutamate metabolism 2 LLUN009954-PA;LLUN009509-PA MetaCyc: PWY-7181 Pyrimidine deoxyribonucleosides degradation 2 LLUN000064-PA;LLUN012848-PA KEGG: 00250+6.3.5.4 Alanine, aspartate and glutamate metabolism 1 LLUN007275-PA Reactome: R-HSA-156588 Glucuronidation 39 LLUN005661-PA;LLUN002519-PA;LLUN008618-PA;LLUN010237-PA;LLUN003264-PA;LLUN012681-PA;LLUN006385-PA;LLUN001631-PA;LLUN001920-PA;LLUN011532-PA;LLUN008760-PA;LLUN005471-PA;LLUN006990-PA;LLUN012262-PA;LLUN011196-PA;LLUN005107-PA;LLUN007145-PA;LLUN001326-PA;LLUN005727-PA;LLUN009617-PA;LLUN001921-PA;LLUN010880-PA;LLUN012264-PA;LLUN001919-PA;LLUN012263-PA;LLUN003265-PA;LLUN013030-PA;LLUN011376-PA;LLUN005660-PA;LLUN005726-PA;LLUN008914-PA;LLUN010649-PA;LLUN005106-PA;LLUN008869-PA;LLUN003065-PA;LLUN000842-PA;LLUN010879-PA;LLUN006386-PA;LLUN005108-PA Reactome: R-HSA-209905 Catecholamine biosynthesis 1 LLUN000709-PA KEGG: 04070+2.7.1.153 Phosphatidylinositol signaling system 1 LLUN006224-PA MetaCyc: PWY-7725 Arachidonate biosynthesis V (8-detaturase, mammals) 18 LLUN009068-PA;LLUN001586-PA;LLUN003202-PA;LLUN001585-PA;LLUN008915-PA;LLUN011428-PA;LLUN002534-PA;LLUN001587-PA;LLUN003913-PA;LLUN005813-PA;LLUN011810-PA;LLUN000999-PA;LLUN011712-PA;LLUN003915-PA;LLUN004698-PA;LLUN004697-PA;LLUN003366-PA;LLUN002535-PA Reactome: R-HSA-4419969 Depolymerisation of the Nuclear Lamina 2 LLUN011507-PA;LLUN003443-PA KEGG: 00500+2.7.7.9 Starch and sucrose metabolism 1 LLUN009234-PA Reactome: R-HSA-5673000 RAF activation 2 LLUN011839-PA;LLUN011378-PA Reactome: R-HSA-426486 Small interfering RNA (siRNA) biogenesis 2 LLUN004906-PA;LLUN009676-PA Reactome: R-HSA-3000157 Laminin interactions 6 LLUN001511-PA;LLUN000590-PA;LLUN004092-PA;LLUN000595-PA;LLUN000003-PA;LLUN000591-PA KEGG: 00982+1.1.1.1 Drug metabolism - cytochrome P450 1 LLUN012888-PA Reactome: R-HSA-9636383 Prevention of phagosomal-lysosomal fusion 2 LLUN012461-PA;LLUN005530-PA Reactome: R-HSA-5628897 TP53 Regulates Metabolic Genes 28 LLUN002936-PA;LLUN005447-PA;LLUN000750-PA;LLUN006174-PA;LLUN009495-PA;LLUN009886-PA;LLUN003801-PA;LLUN009676-PA;LLUN011105-PA;LLUN006836-PA;LLUN003047-PA;LLUN000547-PA;LLUN009768-PA;LLUN012130-PA;LLUN002417-PA;LLUN000660-PA;LLUN009510-PA;LLUN011140-PA;LLUN004171-PA;LLUN011888-PA;LLUN005309-PA;LLUN000751-PA;LLUN003543-PA;LLUN005085-PA;LLUN012849-PA;LLUN006440-PA;LLUN000137-PA;LLUN006176-PA Reactome: R-HSA-9009391 Extra-nuclear estrogen signaling 1 LLUN006897-PA KEGG: 00400+2.5.1.19 Phenylalanine, tyrosine and tryptophan biosynthesis 1 LLUN012009-PA KEGG: 00901+2.7.1.222 Indole alkaloid biosynthesis 16 LLUN008033-PA;LLUN006421-PA;LLUN006422-PA;LLUN003206-PA;LLUN007629-PA;LLUN012747-PA;LLUN004808-PA;LLUN009043-PA;LLUN007963-PA;LLUN006054-PA;LLUN007962-PA;LLUN007396-PA;LLUN012499-PA;LLUN009665-PA;LLUN006423-PA;LLUN010575-PA KEGG: 00564+4.3.1.7 Glycerophospholipid metabolism 1 LLUN000232-PA Reactome: R-HSA-983712 Ion channel transport 13 LLUN004087-PA;LLUN012843-PA;LLUN012460-PA;LLUN012577-PA;LLUN005731-PA;LLUN005643-PA;LLUN002284-PA;LLUN002836-PA;LLUN002241-PA;LLUN010285-PA;LLUN004088-PA;LLUN004638-PA;LLUN005072-PA KEGG: 00514+2.4.1.109 Other types of O-glycan biosynthesis 4 LLUN006126-PA;LLUN008266-PA;LLUN004843-PA;LLUN004509-PA MetaCyc: PWY-5482 Pyruvate fermentation to acetate II 3 LLUN000223-PA;LLUN007189-PA;LLUN009622-PA Reactome: R-HSA-450520 HuR (ELAVL1) binds and stabilizes mRNA 1 LLUN009748-PA KEGG: 00520+4.2.1.47 Amino sugar and nucleotide sugar metabolism 1 LLUN000234-PA Reactome: R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 24 LLUN010911-PA;LLUN009178-PA;LLUN001676-PA;LLUN007798-PA;LLUN008353-PA;LLUN000521-PA;LLUN011861-PA;LLUN009747-PA;LLUN002995-PA;LLUN001654-PA;LLUN001290-PA;LLUN003321-PA;LLUN009131-PA;LLUN009871-PA;LLUN002218-PA;LLUN008120-PA;LLUN009648-PA;LLUN011586-PA;LLUN001301-PA;LLUN012654-PA;LLUN010602-PA;LLUN007911-PA;LLUN001565-PA;LLUN011260-PA KEGG: 00620+1.1.1.79 Pyruvate metabolism 1 LLUN001199-PA Reactome: R-HSA-5658034 HHAT G278V abrogates palmitoylation of Hh-Np 3 LLUN010850-PA;LLUN005656-PA;LLUN001628-PA MetaCyc: PWY-5938 Pyruvate fermentation to (R)-acetoin I 2 LLUN000551-PA;LLUN000044-PA MetaCyc: PWY-6952 Glycerophosphodiester degradation 2 LLUN000668-PA;LLUN010207-PA Reactome: R-HSA-8939256 RUNX1 regulates transcription of genes involved in WNT signaling 3 LLUN009498-PA;LLUN009496-PA;LLUN009497-PA KEGG: 00524+2.7.1.1 Neomycin, kanamycin and gentamicin biosynthesis 2 LLUN003849-PA;LLUN005483-PA Reactome: R-HSA-432722 Golgi Associated Vesicle Biogenesis 1 LLUN011835-PA Reactome: R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 7 LLUN011378-PA;LLUN010831-PA;LLUN009748-PA;LLUN003438-PA;LLUN004221-PA;LLUN002475-PA;LLUN009963-PA Reactome: R-HSA-5655862 Translesion synthesis by POLK 7 LLUN007180-PA;LLUN005530-PA;LLUN011570-PA;LLUN008476-PA;LLUN012973-PA;LLUN001634-PA;LLUN009996-PA KEGG: 00010+2.7.1.11 Glycolysis / Gluconeogenesis 3 LLUN002937-PA;LLUN002938-PA;LLUN000534-PA Reactome: R-HSA-8939211 ESR-mediated signaling 1 LLUN002516-PA Reactome: R-HSA-2995383 Initiation of Nuclear Envelope Reformation 1 LLUN011507-PA Reactome: R-HSA-983189 Kinesins 43 LLUN009062-PA;LLUN002033-PA;LLUN006353-PA;LLUN010341-PA;LLUN005756-PA;LLUN000702-PA;LLUN000700-PA;LLUN003209-PA;LLUN009334-PA;LLUN003020-PA;LLUN002581-PA;LLUN003554-PA;LLUN011307-PA;LLUN003227-PA;LLUN003961-PA;LLUN006723-PA;LLUN011306-PA;LLUN004396-PA;LLUN008315-PA;LLUN006930-PA;LLUN003021-PA;LLUN003553-PA;LLUN004100-PA;LLUN011766-PA;LLUN011179-PA;LLUN000039-PA;LLUN000701-PA;LLUN009505-PA;LLUN008144-PA;LLUN002031-PA;LLUN012820-PA;LLUN006124-PA;LLUN005998-PA;LLUN003258-PA;LLUN007825-PA;LLUN008923-PA;LLUN007288-PA;LLUN009960-PA;LLUN002707-PA;LLUN001322-PA;LLUN007801-PA;LLUN002972-PA;LLUN003240-PA Reactome: R-HSA-1566948 Elastic fibre formation 1 LLUN001692-PA Reactome: R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 35 LLUN012273-PA;LLUN000089-PA;LLUN008477-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN004794-PA;LLUN004076-PA;LLUN005610-PA;LLUN008960-PA;LLUN005440-PA;LLUN003501-PA;LLUN002054-PA;LLUN009994-PA;LLUN004861-PA;LLUN010393-PA;LLUN011115-PA;LLUN012429-PA;LLUN002998-PA;LLUN005530-PA;LLUN002894-PA;LLUN000848-PA;LLUN003629-PA;LLUN005030-PA;LLUN013272-PA;LLUN004508-PA;LLUN005593-PA;LLUN000845-PA;LLUN006525-PA;LLUN007882-PA;LLUN009980-PA;LLUN006627-PA;LLUN012097-PA;LLUN008342-PA;LLUN004685-PA MetaCyc: PWY-7619 Juniperonate biosynthesis 18 LLUN001586-PA;LLUN009068-PA;LLUN003202-PA;LLUN001585-PA;LLUN011428-PA;LLUN008915-PA;LLUN001587-PA;LLUN002534-PA;LLUN003913-PA;LLUN011810-PA;LLUN005813-PA;LLUN000999-PA;LLUN011712-PA;LLUN003915-PA;LLUN004698-PA;LLUN004697-PA;LLUN003366-PA;LLUN002535-PA Reactome: R-HSA-204626 Hypusine synthesis from eIF5A-lysine 2 LLUN011194-PA;LLUN009155-PA MetaCyc: PWY-5849 Menaquinol-6 biosynthesis 2 LLUN000579-PA;LLUN007379-PA Reactome: R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 7 LLUN012097-PA;LLUN007882-PA;LLUN004076-PA;LLUN004685-PA;LLUN000848-PA;LLUN012273-PA;LLUN000845-PA Reactome: R-HSA-2161541 Abacavir metabolism 1 LLUN000522-PA Reactome: R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 1 LLUN007325-PA MetaCyc: PWY-6453 Stigma estolide biosynthesis 3 LLUN000308-PA;LLUN003443-PA;LLUN008689-PA Reactome: R-HSA-73614 Pyrimidine salvage 4 LLUN012848-PA;LLUN000578-PA;LLUN000064-PA;LLUN006688-PA KEGG: 00791+3.5.1.131 Atrazine degradation 1 LLUN000192-PA KEGG: 00281+4.2.1.17+1.1.1.35 Geraniol degradation 4 LLUN000586-PA;LLUN008953-PA;LLUN007706-PA;LLUN011561-PA MetaCyc: PWY-5104 L-isoleucine biosynthesis IV 2 LLUN000044-PA;LLUN000551-PA MetaCyc: PWY-1801 Formaldehyde oxidation II (glutathione-dependent) 2 LLUN012888-PA;LLUN009769-PA Reactome: R-HSA-8939242 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes 3 LLUN009498-PA;LLUN009496-PA;LLUN009497-PA Reactome: R-HSA-72764 Eukaryotic Translation Termination 62 LLUN005442-PA;LLUN002390-PA;LLUN007563-PA;LLUN003780-PA;LLUN012611-PA;LLUN000340-PA;LLUN008995-PA;LLUN010052-PA;LLUN000494-PA;LLUN005586-PA;LLUN007812-PA;LLUN004909-PA;LLUN004193-PA;LLUN010136-PA;LLUN012390-PA;LLUN009998-PA;LLUN005530-PA;LLUN010358-PA;LLUN009774-PA;LLUN008357-PA;LLUN008530-PA;LLUN006512-PA;LLUN002560-PA;LLUN012333-PA;LLUN001675-PA;LLUN003373-PA;LLUN006863-PA;LLUN000856-PA;LLUN012053-PA;LLUN007972-PA;LLUN001670-PA;LLUN006093-PA;LLUN012076-PA;LLUN004837-PA;LLUN000493-PA;LLUN011304-PA;LLUN007100-PA;LLUN004402-PA;LLUN005594-PA;LLUN012474-PA;LLUN002787-PA;LLUN012495-PA;LLUN003515-PA;LLUN003497-PA;LLUN005084-PA;LLUN003524-PA;LLUN011174-PA;LLUN007733-PA;LLUN006098-PA;LLUN002287-PA;LLUN010153-PA;LLUN007661-PA;LLUN003033-PA;LLUN003745-PA;LLUN009419-PA;LLUN009177-PA;LLUN006179-PA;LLUN008597-PA;LLUN006279-PA;LLUN001569-PA;LLUN010350-PA;LLUN008152-PA Reactome: R-HSA-389359 CD28 dependent Vav1 pathway 1 LLUN006122-PA Reactome: R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 9 LLUN005447-PA;LLUN009495-PA;LLUN002337-PA;LLUN006440-PA;LLUN005085-PA;LLUN012849-PA;LLUN003047-PA;LLUN006176-PA;LLUN012771-PA Reactome: R-HSA-1483191 Synthesis of PC 7 LLUN007595-PA;LLUN008475-PA;LLUN003443-PA;LLUN004779-PA;LLUN009517-PA;LLUN011678-PA;LLUN011594-PA KEGG: 00330+1.2.1.88 Arginine and proline metabolism 2 LLUN009509-PA;LLUN009954-PA Reactome: R-HSA-72702 Ribosomal scanning and start codon recognition 32 LLUN007812-PA;LLUN004513-PA;LLUN011199-PA;LLUN000340-PA;LLUN012611-PA;LLUN007563-PA;LLUN002560-PA;LLUN011029-PA;LLUN006512-PA;LLUN008357-PA;LLUN007425-PA;LLUN005530-PA;LLUN005308-PA;LLUN004402-PA;LLUN012076-PA;LLUN007100-PA;LLUN001670-PA;LLUN004621-PA;LLUN000856-PA;LLUN012053-PA;LLUN008680-PA;LLUN003373-PA;LLUN006863-PA;LLUN003999-PA;LLUN001569-PA;LLUN001948-PA;LLUN003033-PA;LLUN003745-PA;LLUN009177-PA;LLUN004682-PA;LLUN002287-PA;LLUN006098-PA MetaCyc: PWY-6367 D-myo-inositol-5-phosphate metabolism 5 LLUN008499-PA;LLUN003912-PA;LLUN004409-PA;LLUN008703-PA;LLUN007371-PA KEGG: 00860+6.1.1.17 Porphyrin and chlorophyll metabolism 2 LLUN009306-PA;LLUN000232-PA MetaCyc: PWY-7340 9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast) 2 LLUN000586-PA;LLUN000585-PA Reactome: R-HSA-181430 Norepinephrine Neurotransmitter Release Cycle 1 LLUN011055-PA KEGG: 00860+2.3.1.37 Porphyrin and chlorophyll metabolism 1 LLUN005927-PA MetaCyc: PWY-5129 Sphingolipid biosynthesis (plants) 1 LLUN004238-PA Reactome: R-HSA-156581 Methylation 5 LLUN002440-PA;LLUN000141-PA;LLUN000910-PA;LLUN000281-PA;LLUN009623-PA MetaCyc: PWY-6538 Caffeine degradation III (bacteria, via demethylation) 1 LLUN009431-PA Reactome: R-HSA-389513 CTLA4 inhibitory signaling 1 LLUN011378-PA Reactome: R-HSA-6802952 Signaling by BRAF and RAF fusions 5 LLUN011839-PA;LLUN002516-PA;LLUN011692-PA;LLUN008945-PA;LLUN008935-PA Reactome: R-HSA-426496 Post-transcriptional silencing by small RNAs 2 LLUN009676-PA;LLUN005309-PA KEGG: 00550+6.3.2.10 Peptidoglycan biosynthesis 1 LLUN000042-PA Reactome: R-HSA-5576894 Phase 1 - inactivation of fast Na+ channels 2 LLUN001336-PA;LLUN009709-PA KEGG: 00720+1.5.1.20 Carbon fixation pathways in prokaryotes 1 LLUN000542-PA Reactome: R-HSA-418890 Role of second messengers in netrin-1 signaling 3 LLUN007904-PA;LLUN002249-PA;LLUN000955-PA KEGG: 00230+3.5.4.4 Purine metabolism 1 LLUN004537-PA Reactome: R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 2 LLUN008044-PA;LLUN011839-PA Reactome: R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 1 LLUN002516-PA KEGG: 00310+1.2.4.2 Lysine degradation 1 LLUN008349-PA KEGG: 00780+6.3.3.3 Biotin metabolism 1 LLUN011577-PA KEGG: 00620+2.3.3.13 Pyruvate metabolism 1 LLUN000046-PA KEGG: 00230+3.6.1.66 Purine metabolism 2 LLUN006214-PA;LLUN000916-PA Reactome: R-HSA-1482925 Acyl chain remodelling of PG 3 LLUN003536-PA;LLUN008580-PA;LLUN001410-PA MetaCyc: PWY-6124 Inosine-5'-phosphate biosynthesis II 4 LLUN002429-PA;LLUN004569-PA;LLUN008637-PA;LLUN010078-PA Reactome: R-HSA-446203 Asparagine N-linked glycosylation 4 LLUN004112-PA;LLUN010736-PA;LLUN004474-PA;LLUN012000-PA KEGG: 00785+2.3.1.181 Lipoic acid metabolism 2 LLUN008045-PA;LLUN011228-PA Reactome: R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 12 LLUN003873-PA;LLUN010444-PA;LLUN008644-PA;LLUN006111-PA;LLUN010902-PA;LLUN011364-PA;LLUN010873-PA;LLUN002369-PA;LLUN005530-PA;LLUN011136-PA;LLUN002616-PA;LLUN010803-PA KEGG: 00240+2.7.4.22 Pyrimidine metabolism 1 LLUN000173-PA MetaCyc: PWY-5290 Secologanin and strictosidine biosynthesis 1 LLUN000568-PA Reactome: R-HSA-9613354 Lipophagy 1 LLUN003047-PA KEGG: 00230+2.7.4.8 Purine metabolism 4 LLUN003702-PA;LLUN000522-PA;LLUN006961-PA;LLUN005804-PA Reactome: R-HSA-4086398 Ca2+ pathway 5 LLUN005309-PA;LLUN006125-PA;LLUN009676-PA;LLUN004972-PA;LLUN000812-PA Reactome: R-HSA-112311 Neurotransmitter clearance 3 LLUN011678-PA;LLUN009517-PA;LLUN007595-PA Reactome: R-HSA-8849175 Threonine catabolism 3 LLUN000088-PA;LLUN009500-PA;LLUN010320-PA Reactome: R-HSA-189085 Digestion of dietary carbohydrate 47 LLUN006388-PA;LLUN005783-PA;LLUN009001-PA;LLUN008127-PA;LLUN009935-PA;LLUN010983-PA;LLUN006635-PA;LLUN003576-PA;LLUN011469-PA;LLUN007851-PA;LLUN002661-PA;LLUN004755-PA;LLUN009934-PA;LLUN005305-PA;LLUN007997-PA;LLUN004266-PA;LLUN009051-PA;LLUN008364-PA;LLUN007700-PA;LLUN011643-PA;LLUN007726-PA;LLUN011950-PA;LLUN012359-PA;LLUN004641-PA;LLUN009110-PA;LLUN002160-PA;LLUN005777-PA;LLUN012483-PA;LLUN003575-PA;LLUN002662-PA;LLUN008566-PA;LLUN002430-PA;LLUN006915-PA;LLUN013130-PA;LLUN009566-PA;LLUN003418-PA;LLUN005612-PA;LLUN001720-PA;LLUN012710-PA;LLUN008102-PA;LLUN005932-PA;LLUN009000-PA;LLUN004640-PA;LLUN009050-PA;LLUN002625-PA;LLUN006280-PA;LLUN011345-PA Reactome: R-HSA-418555 G alpha (s) signalling events 2 LLUN004430-PA;LLUN004610-PA MetaCyc: PWY-761 Rhizobactin 1021 biosynthesis 1 LLUN008772-PA MetaCyc: PWY-6389 Pyruvate fermentation to (S)-acetoin 3 LLUN000551-PA;LLUN000044-PA;LLUN008647-PA KEGG: 00720+1.5.1.5+3.5.4.9 Carbon fixation pathways in prokaryotes 3 LLUN011200-PA;LLUN010882-PA;LLUN000777-PA Reactome: R-HSA-2408557 Selenocysteine synthesis 62 LLUN005084-PA;LLUN003497-PA;LLUN003524-PA;LLUN012495-PA;LLUN003515-PA;LLUN007661-PA;LLUN008398-PA;LLUN011174-PA;LLUN007733-PA;LLUN006098-PA;LLUN002287-PA;LLUN010153-PA;LLUN003745-PA;LLUN003033-PA;LLUN009419-PA;LLUN009177-PA;LLUN001569-PA;LLUN008152-PA;LLUN010350-PA;LLUN008597-PA;LLUN006279-PA;LLUN001675-PA;LLUN003373-PA;LLUN006863-PA;LLUN001670-PA;LLUN007972-PA;LLUN000856-PA;LLUN012053-PA;LLUN004402-PA;LLUN006093-PA;LLUN000493-PA;LLUN012076-PA;LLUN004837-PA;LLUN011304-PA;LLUN007100-PA;LLUN005594-PA;LLUN012474-PA;LLUN002787-PA;LLUN009998-PA;LLUN005530-PA;LLUN010358-PA;LLUN009774-PA;LLUN008357-PA;LLUN008530-PA;LLUN006512-PA;LLUN002560-PA;LLUN012333-PA;LLUN002390-PA;LLUN007563-PA;LLUN003780-PA;LLUN012611-PA;LLUN005442-PA;LLUN010052-PA;LLUN000494-PA;LLUN000340-PA;LLUN008995-PA;LLUN004193-PA;LLUN010136-PA;LLUN004909-PA;LLUN005586-PA;LLUN007812-PA;LLUN012390-PA MetaCyc: PWY-5912 2'-deoxymugineic acid phytosiderophore biosynthesis 3 LLUN002440-PA;LLUN009623-PA;LLUN000910-PA KEGG: 00900+1.1.1.34 Terpenoid backbone biosynthesis 2 LLUN006161-PA;LLUN006160-PA KEGG: 00620+3.6.1.7 Pyruvate metabolism 2 LLUN004267-PA;LLUN003978-PA KEGG: 00020+1.1.5.4 Citrate cycle (TCA cycle) 1 LLUN001228-PA MetaCyc: PWY-6936 Seleno-amino acid biosynthesis (plants) 5 LLUN000310-PA;LLUN000532-PA;LLUN000578-PA;LLUN000230-PA;LLUN004715-PA Reactome: R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 16 LLUN003321-PA;LLUN001290-PA;LLUN001654-PA;LLUN009747-PA;LLUN011861-PA;LLUN000521-PA;LLUN007798-PA;LLUN001676-PA;LLUN009178-PA;LLUN011260-PA;LLUN007911-PA;LLUN011586-PA;LLUN009648-PA;LLUN008120-PA;LLUN009871-PA;LLUN002218-PA Reactome: R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 2 LLUN010444-PA;LLUN008644-PA KEGG: 00300+1.17.1.8 Lysine biosynthesis 1 LLUN000049-PA KEGG: 00240+3.6.1.23 Pyrimidine metabolism 1 LLUN000524-PA MetaCyc: PWY-6683 Assimilatory sulfate reduction III 2 LLUN000318-PA;LLUN000677-PA Reactome: R-HSA-5654700 FRS-mediated FGFR2 signaling 1 LLUN002128-PA MetaCyc: PWY-6470 Peptidoglycan biosynthesis V (beta-lactam resistance) 6 LLUN000674-PA;LLUN002437-PA;LLUN000041-PA;LLUN000042-PA;LLUN011710-PA;LLUN011947-PA KEGG: 00020+1.1.1.42 Citrate cycle (TCA cycle) 1 LLUN012407-PA KEGG: 00040+2.7.7.9 Pentose and glucuronate interconversions 1 LLUN009234-PA Reactome: R-HSA-1483213 Synthesis of PE 5 LLUN002860-PA;LLUN000263-PA;LLUN000568-PA;LLUN003443-PA;LLUN010169-PA MetaCyc: PWY-6731 Starch degradation III 4 LLUN001762-PA;LLUN000667-PA;LLUN000295-PA;LLUN000671-PA Reactome: R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs 27 LLUN005003-PA;LLUN004289-PA;LLUN009383-PA;LLUN006622-PA;LLUN008147-PA;LLUN008308-PA;LLUN006912-PA;LLUN006116-PA;LLUN006432-PA;LLUN002554-PA;LLUN005268-PA;LLUN011181-PA;LLUN000357-PA;LLUN007852-PA;LLUN010208-PA;LLUN009731-PA;LLUN003008-PA;LLUN011827-PA;LLUN007899-PA;LLUN011263-PA;LLUN009797-PA;LLUN005004-PA;LLUN006144-PA;LLUN003608-PA;LLUN007002-PA;LLUN003429-PA;LLUN006911-PA Reactome: R-HSA-9646399 Aggrephagy 21 LLUN011179-PA;LLUN006353-PA;LLUN000039-PA;LLUN004100-PA;LLUN011766-PA;LLUN009062-PA;LLUN003553-PA;LLUN012758-PA;LLUN009963-PA;LLUN002581-PA;LLUN003209-PA;LLUN005530-PA;LLUN007825-PA;LLUN003554-PA;LLUN006723-PA;LLUN008923-PA;LLUN001322-PA;LLUN011108-PA;LLUN002707-PA;LLUN000749-PA;LLUN003240-PA MetaCyc: PWY-5030 L-histidine degradation III 3 LLUN000777-PA;LLUN011200-PA;LLUN010882-PA MetaCyc: PWY-6908 Thiamine diphosphate biosynthesis IV (eukaryotes) 1 LLUN000288-PA MetaCyc: PWY-4702 Phytate degradation I 2 LLUN000211-PA;LLUN003712-PA Reactome: R-HSA-2470946 Cohesin Loading onto Chromatin 2 LLUN004810-PA;LLUN009699-PA KEGG: 00564+1.1.1.94 Glycerophospholipid metabolism 1 LLUN008432-PA KEGG: 00920+2.3.1.30 Sulfur metabolism 1 LLUN000532-PA Reactome: R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 8 LLUN002107-PA;LLUN001285-PA;LLUN010843-PA;LLUN012338-PA;LLUN001750-PA;LLUN002499-PA;LLUN003861-PA;LLUN007755-PA Reactome: R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 3 LLUN005530-PA;LLUN000376-PA;LLUN000073-PA Reactome: R-HSA-3214847 HATs acetylate histones 25 LLUN002127-PA;LLUN000599-PA;LLUN005898-PA;LLUN006272-PA;LLUN002122-PA;LLUN013219-PA;LLUN005806-PA;LLUN008159-PA;LLUN007570-PA;LLUN011799-PA;LLUN011007-PA;LLUN008644-PA;LLUN000874-PA;LLUN008863-PA;LLUN010444-PA;LLUN010746-PA;LLUN010647-PA;LLUN011878-PA;LLUN006408-PA;LLUN010636-PA;LLUN011503-PA;LLUN003864-PA;LLUN001059-PA;LLUN006762-PA;LLUN008306-PA KEGG: 00220+2.6.1.1 Arginine biosynthesis 1 LLUN009219-PA MetaCyc: PWY-8015 Glycine degradation (Stickland reaction) 2 LLUN007189-PA;LLUN009622-PA KEGG: 00290+1.1.1.85 Valine, leucine and isoleucine biosynthesis 1 LLUN000046-PA MetaCyc: PWY-6167 Flavin biosynthesis II (archaea) 1 LLUN000051-PA MetaCyc: PWY-6700 Queuosine biosynthesis I (de novo) 4 LLUN000743-PA;LLUN000263-PA;LLUN002433-PA;LLUN000167-PA MetaCyc: PWY-6012 Acyl carrier protein metabolism 1 LLUN006777-PA KEGG: 00630+2.3.3.9 Glyoxylate and dicarboxylate metabolism 2 LLUN000144-PA;LLUN007673-PA Reactome: R-HSA-8948751 Regulation of PTEN stability and activity 32 LLUN005593-PA;LLUN004508-PA;LLUN005030-PA;LLUN013272-PA;LLUN003629-PA;LLUN002894-PA;LLUN005530-PA;LLUN008342-PA;LLUN006627-PA;LLUN009980-PA;LLUN006525-PA;LLUN005610-PA;LLUN004794-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN008475-PA;LLUN008477-PA;LLUN006158-PA;LLUN000089-PA;LLUN002998-PA;LLUN010393-PA;LLUN011115-PA;LLUN012429-PA;LLUN009994-PA;LLUN004861-PA;LLUN002054-PA;LLUN006267-PA;LLUN005440-PA;LLUN003501-PA;LLUN008960-PA;LLUN012548-PA KEGG: 00900+1.17.7.4 Terpenoid backbone biosynthesis 1 LLUN000050-PA KEGG: 00520+5.3.1.8 Amino sugar and nucleotide sugar metabolism 1 LLUN011806-PA MetaCyc: PWY-66 GDP-L-fucose biosynthesis I (from GDP-D-mannose) 1 LLUN000234-PA MetaCyc: PWY-7268 NAD/NADP-NADH/NADPH cytosolic interconversion (yeast) 3 LLUN008323-PA;LLUN009154-PA;LLUN012407-PA Reactome: R-HSA-381753 Olfactory Signaling Pathway 1 LLUN004961-PA KEGG: 00010+2.3.1.12 Glycolysis / Gluconeogenesis 1 LLUN000030-PA Reactome: R-HSA-5696400 Dual Incision in GG-NER 15 LLUN002277-PA;LLUN002995-PA;LLUN001634-PA;LLUN012973-PA;LLUN008719-PA;LLUN009996-PA;LLUN010911-PA;LLUN001301-PA;LLUN012654-PA;LLUN002231-PA;LLUN008353-PA;LLUN008476-PA;LLUN011570-PA;LLUN005530-PA;LLUN007180-PA KEGG: 00230+3.5.2.17 Purine metabolism 1 LLUN009875-PA Reactome: R-HSA-8949613 Cristae formation 17 LLUN001365-PA;LLUN004166-PA;LLUN013185-PA;LLUN011510-PA;LLUN009889-PA;LLUN009625-PA;LLUN001867-PA;LLUN000176-PA;LLUN008019-PA;LLUN000039-PA;LLUN008259-PA;LLUN003125-PA;LLUN001187-PA;LLUN001186-PA;LLUN009056-PA;LLUN002393-PA;LLUN005072-PA Reactome: R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 1 LLUN004972-PA Reactome: R-HSA-5654726 Negative regulation of FGFR1 signaling 2 LLUN002516-PA;LLUN005530-PA KEGG: 00960+2.6.1.1 Tropane, piperidine and pyridine alkaloid biosynthesis 1 LLUN009219-PA Reactome: R-HSA-5610780 Degradation of GLI1 by the proteasome 31 LLUN000089-PA;LLUN002894-PA;LLUN005530-PA;LLUN005610-PA;LLUN005593-PA;LLUN004508-PA;LLUN004794-PA;LLUN005030-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN013272-PA;LLUN003629-PA;LLUN008477-PA;LLUN005440-PA;LLUN003501-PA;LLUN006525-PA;LLUN008960-PA;LLUN012548-PA;LLUN002998-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN008342-PA;LLUN006111-PA;LLUN009994-PA;LLUN006627-PA;LLUN004861-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA Reactome: R-HSA-264876 Insulin processing 5 LLUN011106-PA;LLUN002928-PA;LLUN007564-PA;LLUN003747-PA;LLUN012444-PA KEGG: 00270+2.5.1.48 Cysteine and methionine metabolism 1 LLUN000541-PA MetaCyc: PWY-5491 Diethylphosphate degradation 12 LLUN012626-PA;LLUN002910-PA;LLUN006398-PA;LLUN008360-PA;LLUN006396-PA;LLUN005387-PA;LLUN006399-PA;LLUN002237-PA;LLUN008172-PA;LLUN008359-PA;LLUN006397-PA;LLUN011373-PA Reactome: R-HSA-69202 Cyclin E associated events during G1/S transition 4 LLUN001786-PA;LLUN004788-PA;LLUN001565-PA;LLUN010602-PA Reactome: R-HSA-5579006 Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) 3 LLUN008974-PA;LLUN012049-PA;LLUN008975-PA Reactome: R-HSA-390247 Beta-oxidation of very long chain fatty acids 1 LLUN000759-PA MetaCyc: PWY-6964 Ammonia assimilation cycle II 4 LLUN000514-PA;LLUN002676-PA;LLUN000515-PA;LLUN002238-PA KEGG: 00290+4.2.1.33 Valine, leucine and isoleucine biosynthesis 4 LLUN006140-PA;LLUN006873-PA;LLUN000046-PA;LLUN011435-PA MetaCyc: PWY-7571 Ferrichrome A biosynthesis 1 LLUN007815-PA KEGG: 00740+3.6.1.9 Riboflavin metabolism 3 LLUN003890-PA;LLUN006214-PA;LLUN000110-PA KEGG: 00531+3.2.1.35 Glycosaminoglycan degradation 1 LLUN009274-PA Reactome: R-HSA-196819 Vitamin B1 (thiamin) metabolism 2 LLUN000148-PA;LLUN005327-PA KEGG: 00230+1.17.4.1 Purine metabolism 2 LLUN008193-PA;LLUN001080-PA Reactome: R-HSA-422085 Synthesis, secretion, and deacylation of Ghrelin 6 LLUN011678-PA;LLUN009517-PA;LLUN009969-PA;LLUN001397-PA;LLUN007595-PA;LLUN005822-PA KEGG: 00480+2.5.1.16 Glutathione metabolism 2 LLUN010439-PA;LLUN006330-PA Reactome: R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 2 LLUN005530-PA;LLUN000589-PA MetaCyc: PWY-5353 Arachidonate biosynthesis I (6-desaturase, lower eukaryotes) 2 LLUN011810-PA;LLUN009068-PA Reactome: R-HSA-159227 Transport of the SLBP independent Mature mRNA 11 LLUN003438-PA;LLUN001776-PA;LLUN004789-PA;LLUN008374-PA;LLUN013269-PA;LLUN008894-PA;LLUN012529-PA;LLUN010831-PA;LLUN001860-PA;LLUN007599-PA;LLUN009131-PA Reactome: R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 19 LLUN010911-PA;LLUN009178-PA;LLUN001676-PA;LLUN008353-PA;LLUN004026-PA;LLUN005530-PA;LLUN000521-PA;LLUN011861-PA;LLUN002995-PA;LLUN011209-PA;LLUN001290-PA;LLUN006559-PA;LLUN009871-PA;LLUN002749-PA;LLUN012654-PA;LLUN001301-PA;LLUN010602-PA;LLUN007911-PA;LLUN001565-PA KEGG: 00051+3.1.3.11 Fructose and mannose metabolism 2 LLUN008377-PA;LLUN000273-PA MetaCyc: PWY-2942 L-lysine biosynthesis III 2 LLUN000049-PA;LLUN012256-PA MetaCyc: PWY-7592 Arachidonate biosynthesis III (6-desaturase, mammals) 2 LLUN011810-PA;LLUN009068-PA MetaCyc: PWY-7733 3-hydroxyquinaldate biosynthesis 1 LLUN004035-PA KEGG: 00450+2.1.1.14 Selenocompound metabolism 2 LLUN004715-PA;LLUN000578-PA KEGG: 00680+2.7.9.2 Methane metabolism 1 LLUN012863-PA Reactome: R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 26 LLUN012654-PA;LLUN001301-PA;LLUN006269-PA;LLUN004030-PA;LLUN010602-PA;LLUN009871-PA;LLUN008198-PA;LLUN001565-PA;LLUN007705-PA;LLUN008863-PA;LLUN008159-PA;LLUN007911-PA;LLUN000521-PA;LLUN009851-PA;LLUN008353-PA;LLUN007987-PA;LLUN001676-PA;LLUN010911-PA;LLUN009178-PA;LLUN011583-PA;LLUN008199-PA;LLUN001290-PA;LLUN002995-PA;LLUN001654-PA;LLUN005474-PA;LLUN011861-PA Reactome: R-HSA-1369007 Mitochondrial ABC transporters 2 LLUN011116-PA;LLUN010642-PA Reactome: R-HSA-3214815 HDACs deacetylate histones 5 LLUN011811-PA;LLUN006959-PA;LLUN010803-PA;LLUN010902-PA;LLUN011364-PA KEGG: 00640+2.7.2.1 Propanoate metabolism 2 LLUN009622-PA;LLUN007189-PA Reactome: R-HSA-9616222 Transcriptional regulation of granulopoiesis 3 LLUN009496-PA;LLUN009497-PA;LLUN009498-PA Reactome: R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 1 LLUN005530-PA Reactome: R-HSA-201688 WNT mediated activation of DVL 1 LLUN008475-PA Reactome: R-HSA-392154 Nitric oxide stimulates guanylate cyclase 4 LLUN001108-PA;LLUN002685-PA;LLUN003740-PA;LLUN005887-PA Reactome: R-HSA-1442490 Collagen degradation 5 LLUN009646-PA;LLUN002886-PA;LLUN004942-PA;LLUN004092-PA;LLUN013127-PA KEGG: 00750+1.1.1.290 Vitamin B6 metabolism 1 LLUN013012-PA MetaCyc: PWY-6855 Chitin degradation I (archaea) 11 LLUN005932-PA;LLUN007726-PA;LLUN005795-PA;LLUN007276-PA;LLUN007221-PA;LLUN006418-PA;LLUN009014-PA;LLUN004963-PA;LLUN000048-PA;LLUN001719-PA;LLUN004333-PA Reactome: R-HSA-9634285 Constitutive Signaling by Overexpressed ERBB2 2 LLUN008416-PA;LLUN008205-PA Reactome: R-HSA-3238698 WNT ligand biogenesis and trafficking 15 LLUN002604-PA;LLUN001594-PA;LLUN007777-PA;LLUN005871-PA;LLUN004816-PA;LLUN012578-PA;LLUN008143-PA;LLUN013141-PA;LLUN001143-PA;LLUN001595-PA;LLUN009590-PA;LLUN001144-PA;LLUN009135-PA;LLUN004014-PA;LLUN001427-PA Reactome: R-HSA-2660826 Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant 4 LLUN009254-PA;LLUN003844-PA;LLUN000389-PA;LLUN009680-PA Reactome: R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 2 LLUN008694-PA;LLUN007337-PA Reactome: R-HSA-71336 Pentose phosphate pathway 16 LLUN000065-PA;LLUN010144-PA;LLUN006228-PA;LLUN001184-PA;LLUN010125-PA;LLUN006639-PA;LLUN000903-PA;LLUN000245-PA;LLUN000222-PA;LLUN010699-PA;LLUN000057-PA;LLUN010698-PA;LLUN010519-PA;LLUN012568-PA;LLUN006322-PA;LLUN007784-PA Reactome: R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 1 LLUN011378-PA KEGG: 00260+2.3.1.37 Glycine, serine and threonine metabolism 1 LLUN005927-PA MetaCyc: PWY-7394 Urate conversion to allantoin II 2 LLUN009875-PA;LLUN012972-PA Reactome: R-HSA-3232118 SUMOylation of transcription factors 2 LLUN012898-PA;LLUN011406-PA KEGG: 00230+1.7.1.7 Purine metabolism 1 LLUN000036-PA KEGG: 00230+4.1.1.97 Purine metabolism 1 LLUN012972-PA Reactome: R-HSA-68952 DNA replication initiation 3 LLUN010178-PA;LLUN004948-PA;LLUN006991-PA Reactome: R-HSA-72163 mRNA Splicing - Major Pathway 53 LLUN000521-PA;LLUN010565-PA;LLUN006318-PA;LLUN004026-PA;LLUN004535-PA;LLUN001676-PA;LLUN001764-PA;LLUN006559-PA;LLUN003782-PA;LLUN001712-PA;LLUN001654-PA;LLUN011861-PA;LLUN000235-PA;LLUN002875-PA;LLUN012722-PA;LLUN010308-PA;LLUN001750-PA;LLUN007911-PA;LLUN001711-PA;LLUN004186-PA;LLUN010620-PA;LLUN006313-PA;LLUN004908-PA;LLUN010301-PA;LLUN001421-PA;LLUN009600-PA;LLUN004892-PA;LLUN012338-PA;LLUN009483-PA;LLUN006193-PA;LLUN009178-PA;LLUN012404-PA;LLUN008185-PA;LLUN012167-PA;LLUN011209-PA;LLUN001290-PA;LLUN013182-PA;LLUN002884-PA;LLUN000821-PA;LLUN002749-PA;LLUN002369-PA;LLUN006672-PA;LLUN009131-PA;LLUN009871-PA;LLUN005558-PA;LLUN010121-PA;LLUN010843-PA;LLUN012999-PA;LLUN010614-PA;LLUN006586-PA;LLUN004907-PA;LLUN003731-PA;LLUN003699-PA KEGG: 00051+2.7.1.1 Fructose and mannose metabolism 2 LLUN003849-PA;LLUN005483-PA Reactome: R-HSA-3000170 Syndecan interactions 1 LLUN004191-PA KEGG: 00564+3.1.4.4 Glycerophospholipid metabolism 1 LLUN011702-PA MetaCyc: PWY-6907 Thiamine diphosphate biosynthesis III (Staphylococcus) 1 LLUN000288-PA Reactome: R-HSA-180024 DARPP-32 events 2 LLUN005060-PA;LLUN003214-PA KEGG: 00710+2.7.2.3 Carbon fixation in photosynthetic organisms 2 LLUN010011-PA;LLUN000907-PA KEGG: 00650+2.3.3.10 Butanoate metabolism 1 LLUN007815-PA KEGG: 00550+2.5.1.7 Peptidoglycan biosynthesis 1 LLUN000097-PA KEGG: 00380+4.2.1.17+1.1.1.35 Tryptophan metabolism 4 LLUN011561-PA;LLUN007706-PA;LLUN000586-PA;LLUN008953-PA KEGG: 00550+2.4.1.129 Peptidoglycan biosynthesis 3 LLUN000041-PA;LLUN000674-PA;LLUN011710-PA KEGG: 00270+4.3.1.17 Cysteine and methionine metabolism 2 LLUN009374-PA;LLUN000073-PA KEGG: 00401+2.6.1.1 Novobiocin biosynthesis 1 LLUN009219-PA KEGG: 00190+1.3.5.1 Oxidative phosphorylation 4 LLUN008348-PA;LLUN011041-PA;LLUN012663-PA;LLUN000260-PA Reactome: R-HSA-73772 RNA Polymerase I Promoter Escape 14 LLUN010911-PA;LLUN009871-PA;LLUN001676-PA;LLUN008353-PA;LLUN011477-PA;LLUN012654-PA;LLUN001301-PA;LLUN000521-PA;LLUN010602-PA;LLUN002995-PA;LLUN007911-PA;LLUN001290-PA;LLUN010529-PA;LLUN001565-PA MetaCyc: PWY-7606 Docosahexaenoate biosynthesis III (6-desaturase, mammals) 7 LLUN011810-PA;LLUN011561-PA;LLUN009068-PA;LLUN000585-PA;LLUN007706-PA;LLUN000586-PA;LLUN008953-PA Reactome: R-HSA-2029485 Role of phospholipids in phagocytosis 3 LLUN004972-PA;LLUN004409-PA;LLUN011702-PA Reactome: R-HSA-5627123 RHO GTPases activate PAKs 1 LLUN006122-PA Reactome: R-HSA-5607764 CLEC7A (Dectin-1) signaling 32 LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN008477-PA;LLUN005610-PA;LLUN004794-PA;LLUN000089-PA;LLUN009994-PA;LLUN004861-PA;LLUN006111-PA;LLUN002054-PA;LLUN006267-PA;LLUN002998-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN008960-PA;LLUN007485-PA;LLUN012548-PA;LLUN003501-PA;LLUN005440-PA;LLUN013272-PA;LLUN005030-PA;LLUN003629-PA;LLUN005593-PA;LLUN004508-PA;LLUN005530-PA;LLUN002894-PA;LLUN006627-PA;LLUN009980-PA;LLUN008342-PA;LLUN006525-PA KEGG: 00791+3.5.1.54 Atrazine degradation 1 LLUN001218-PA MetaCyc: PWY-6598 Sciadonate biosynthesis 18 LLUN003913-PA;LLUN005813-PA;LLUN011810-PA;LLUN001585-PA;LLUN009068-PA;LLUN001586-PA;LLUN003202-PA;LLUN008915-PA;LLUN011428-PA;LLUN002534-PA;LLUN001587-PA;LLUN004698-PA;LLUN004697-PA;LLUN003366-PA;LLUN003915-PA;LLUN002535-PA;LLUN011712-PA;LLUN000999-PA Reactome: R-HSA-4570464 SUMOylation of RNA binding proteins 10 LLUN008894-PA;LLUN012529-PA;LLUN010831-PA;LLUN013269-PA;LLUN008374-PA;LLUN004789-PA;LLUN003438-PA;LLUN001776-PA;LLUN007599-PA;LLUN001860-PA MetaCyc: PWY-7985 Oxalate degradation VI 1 LLUN009876-PA Reactome: R-HSA-8943724 Regulation of PTEN gene transcription 10 LLUN005447-PA;LLUN002516-PA;LLUN002798-PA;LLUN004997-PA;LLUN005292-PA;LLUN005085-PA;LLUN012849-PA;LLUN012078-PA;LLUN006440-PA;LLUN006176-PA Reactome: R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 87 LLUN003413-PA;LLUN000845-PA;LLUN007510-PA;LLUN001523-PA;LLUN006525-PA;LLUN006627-PA;LLUN004101-PA;LLUN009980-PA;LLUN004685-PA;LLUN012097-PA;LLUN004312-PA;LLUN005662-PA;LLUN002894-PA;LLUN013272-PA;LLUN004293-PA;LLUN003328-PA;LLUN010590-PA;LLUN009628-PA;LLUN004292-PA;LLUN003501-PA;LLUN009994-PA;LLUN002718-PA;LLUN012135-PA;LLUN007401-PA;LLUN001891-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN007203-PA;LLUN012429-PA;LLUN006902-PA;LLUN000089-PA;LLUN010012-PA;LLUN003215-PA;LLUN004706-PA;LLUN006492-PA;LLUN012562-PA;LLUN006855-PA;LLUN005610-PA;LLUN004076-PA;LLUN012657-PA;LLUN012752-PA;LLUN007569-PA;LLUN007882-PA;LLUN005007-PA;LLUN011993-PA;LLUN010945-PA;LLUN008130-PA;LLUN012373-PA;LLUN011791-PA;LLUN000589-PA;LLUN008342-PA;LLUN011108-PA;LLUN010367-PA;LLUN002080-PA;LLUN003117-PA;LLUN005530-PA;LLUN009423-PA;LLUN000848-PA;LLUN000476-PA;LLUN005030-PA;LLUN003629-PA;LLUN010738-PA;LLUN005593-PA;LLUN004508-PA;LLUN009103-PA;LLUN008960-PA;LLUN012548-PA;LLUN007715-PA;LLUN005440-PA;LLUN004861-PA;LLUN010119-PA;LLUN010116-PA;LLUN006111-PA;LLUN008935-PA;LLUN003016-PA;LLUN006544-PA;LLUN008886-PA;LLUN011115-PA;LLUN010393-PA;LLUN012273-PA;LLUN000503-PA;LLUN006026-PA;LLUN008477-PA;LLUN006158-PA;LLUN002671-PA;LLUN004794-PA KEGG: 00970+6.1.1.2 Aminoacyl-tRNA biosynthesis 2 LLUN003996-PA;LLUN000676-PA Reactome: R-HSA-72187 mRNA 3'-end processing 13 LLUN000821-PA;LLUN011623-PA;LLUN003350-PA;LLUN003699-PA;LLUN003133-PA;LLUN006586-PA;LLUN004892-PA;LLUN009131-PA;LLUN005922-PA;LLUN012404-PA;LLUN003100-PA;LLUN002473-PA;LLUN006672-PA Reactome: R-HSA-71384 Ethanol oxidation 5 LLUN000528-PA;LLUN000894-PA;LLUN000254-PA;LLUN012888-PA;LLUN000217-PA Reactome: R-HSA-73776 RNA Polymerase II Promoter Escape 26 LLUN001290-PA;LLUN011583-PA;LLUN008199-PA;LLUN005474-PA;LLUN011861-PA;LLUN001654-PA;LLUN002995-PA;LLUN008353-PA;LLUN000521-PA;LLUN009851-PA;LLUN010911-PA;LLUN009178-PA;LLUN007987-PA;LLUN001676-PA;LLUN008863-PA;LLUN008198-PA;LLUN007705-PA;LLUN001565-PA;LLUN008159-PA;LLUN007911-PA;LLUN012654-PA;LLUN001301-PA;LLUN006269-PA;LLUN004030-PA;LLUN010602-PA;LLUN009871-PA KEGG: 00680+2.1.2.1 Methane metabolism 3 LLUN000209-PA;LLUN011129-PA;LLUN006558-PA MetaCyc: PWY-7546 Diphthamide biosynthesis II (eukaryotes) 2 LLUN009500-PA;LLUN008287-PA Reactome: R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 11 LLUN012494-PA;LLUN009254-PA;LLUN011975-PA;LLUN000389-PA;LLUN009680-PA;LLUN003844-PA;LLUN005642-PA;LLUN001957-PA;LLUN005530-PA;LLUN007104-PA;LLUN003449-PA MetaCyc: PWY-7180 2-deoxy-alpha-D-ribose 1-phosphate degradation 2 LLUN000065-PA;LLUN000063-PA Reactome: R-HSA-418885 DCC mediated attractive signaling 1 LLUN006122-PA Reactome: R-HSA-480985 Synthesis of dolichyl-phosphate-glucose 1 LLUN000304-PA MetaCyc: PWY-6922 L-Ndelta-acetylornithine biosynthesis 2 LLUN000200-PA;LLUN010744-PA Reactome: R-HSA-110357 Displacement of DNA glycosylase by APEX1 6 LLUN011801-PA;LLUN005053-PA;LLUN000890-PA;LLUN001203-PA;LLUN003410-PA;LLUN002678-PA MetaCyc: PWY-7852 6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium) 2 LLUN012034-PA;LLUN005541-PA Reactome: R-HSA-5218920 VEGFR2 mediated vascular permeability 5 LLUN011192-PA;LLUN012849-PA;LLUN006440-PA;LLUN004283-PA;LLUN007485-PA KEGG: 00270+2.1.1.37 Cysteine and methionine metabolism 3 LLUN001605-PA;LLUN010268-PA;LLUN007122-PA Reactome: R-HSA-351202 Metabolism of polyamines 4 LLUN001283-PA;LLUN010439-PA;LLUN010564-PA;LLUN006330-PA KEGG: 00670+1.5.1.3 One carbon pool by folate 1 LLUN010048-PA Reactome: R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 2 LLUN009996-PA;LLUN008719-PA MetaCyc: PWY-7198 Pyrimidine deoxyribonucleotides de novo biosynthesis IV 12 LLUN010665-PA;LLUN005171-PA;LLUN001080-PA;LLUN012527-PA;LLUN000213-PA;LLUN003082-PA;LLUN000163-PA;LLUN006247-PA;LLUN006605-PA;LLUN011985-PA;LLUN008193-PA;LLUN012628-PA MetaCyc: PWY-5989 Stearate biosynthesis II (bacteria and plants) 4 LLUN000176-PA;LLUN000184-PA;LLUN005169-PA;LLUN003811-PA Reactome: R-HSA-2682334 EPH-Ephrin signaling 2 LLUN000410-PA;LLUN003412-PA MetaCyc: PWY-1042 Glycolysis IV (plant cytosol) 14 LLUN000534-PA;LLUN000907-PA;LLUN012182-PA;LLUN000530-PA;LLUN010011-PA;LLUN000906-PA;LLUN011949-PA;LLUN007408-PA;LLUN009807-PA;LLUN000535-PA;LLUN002938-PA;LLUN002937-PA;LLUN013179-PA;LLUN000832-PA KEGG: 00860+1.3.3.4 Porphyrin and chlorophyll metabolism 1 LLUN008764-PA KEGG: 00630+1.1.1.79+1.1.1.81 Glyoxylate and dicarboxylate metabolism 1 LLUN001199-PA Reactome: R-HSA-139853 Elevation of cytosolic Ca2+ levels 1 LLUN004972-PA KEGG: 00670+2.1.1.45 One carbon pool by folate 2 LLUN000163-PA;LLUN010665-PA MetaCyc: PWY-6365 D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis 1 LLUN009162-PA MetaCyc: PWY-5497 Purine nucleobases degradation II (anaerobic) 11 LLUN011129-PA;LLUN000209-PA;LLUN009876-PA;LLUN011200-PA;LLUN010882-PA;LLUN000777-PA;LLUN000223-PA;LLUN009622-PA;LLUN006558-PA;LLUN007189-PA;LLUN009431-PA Reactome: R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 37 LLUN005610-PA;LLUN004076-PA;LLUN004794-PA;LLUN010012-PA;LLUN003215-PA;LLUN004706-PA;LLUN008477-PA;LLUN000089-PA;LLUN012273-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN009994-PA;LLUN004861-PA;LLUN006267-PA;LLUN002054-PA;LLUN003501-PA;LLUN005440-PA;LLUN008960-PA;LLUN012548-PA;LLUN005593-PA;LLUN004508-PA;LLUN013272-PA;LLUN005030-PA;LLUN003629-PA;LLUN000848-PA;LLUN002894-PA;LLUN005530-PA;LLUN004685-PA;LLUN008342-PA;LLUN012097-PA;LLUN006627-PA;LLUN009980-PA;LLUN006525-PA;LLUN007882-PA;LLUN000845-PA KEGG: 00030+4.1.2.4 Pentose phosphate pathway 1 LLUN000065-PA Reactome: R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 7 LLUN009178-PA;LLUN011861-PA;LLUN007911-PA;LLUN001676-PA;LLUN009871-PA;LLUN001290-PA;LLUN000521-PA Reactome: R-HSA-75876 Synthesis of very long-chain fatty acyl-CoAs 18 LLUN008915-PA;LLUN011428-PA;LLUN001587-PA;LLUN002534-PA;LLUN001585-PA;LLUN001586-PA;LLUN003202-PA;LLUN009068-PA;LLUN011810-PA;LLUN005813-PA;LLUN003913-PA;LLUN011712-PA;LLUN000999-PA;LLUN002535-PA;LLUN003366-PA;LLUN004697-PA;LLUN004698-PA;LLUN003915-PA Reactome: R-HSA-6782135 Dual incision in TC-NER 28 LLUN008719-PA;LLUN011861-PA;LLUN002995-PA;LLUN002277-PA;LLUN001290-PA;LLUN011209-PA;LLUN006559-PA;LLUN009178-PA;LLUN010911-PA;LLUN009996-PA;LLUN001676-PA;LLUN005530-PA;LLUN004026-PA;LLUN008476-PA;LLUN008353-PA;LLUN011570-PA;LLUN000521-PA;LLUN012973-PA;LLUN001634-PA;LLUN007911-PA;LLUN001565-PA;LLUN009871-PA;LLUN007180-PA;LLUN010602-PA;LLUN002231-PA;LLUN012654-PA;LLUN001301-PA;LLUN002749-PA MetaCyc: PWY-6527 Stachyose degradation 7 LLUN005205-PA;LLUN010776-PA;LLUN001202-PA;LLUN003916-PA;LLUN007044-PA;LLUN004037-PA;LLUN009234-PA Reactome: R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 27 LLUN000521-PA;LLUN005530-PA;LLUN004026-PA;LLUN008476-PA;LLUN011570-PA;LLUN008353-PA;LLUN001676-PA;LLUN009996-PA;LLUN009178-PA;LLUN010911-PA;LLUN006559-PA;LLUN001290-PA;LLUN011209-PA;LLUN002995-PA;LLUN006941-PA;LLUN008719-PA;LLUN011861-PA;LLUN010602-PA;LLUN012654-PA;LLUN002749-PA;LLUN001301-PA;LLUN007180-PA;LLUN009871-PA;LLUN001565-PA;LLUN007911-PA;LLUN012973-PA;LLUN001634-PA Reactome: R-HSA-180534 Vpu mediated degradation of CD4 31 LLUN009994-PA;LLUN004861-PA;LLUN006627-PA;LLUN006111-PA;LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN008342-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN008960-PA;LLUN012548-PA;LLUN003501-PA;LLUN005440-PA;LLUN006525-PA;LLUN013272-PA;LLUN003215-PA;LLUN010012-PA;LLUN005030-PA;LLUN004706-PA;LLUN008477-PA;LLUN003629-PA;LLUN005593-PA;LLUN005610-PA;LLUN004508-PA;LLUN004794-PA;LLUN005530-PA;LLUN002894-PA;LLUN000089-PA MetaCyc: PWY-6386 UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) 5 LLUN000042-PA;LLUN000097-PA;LLUN000040-PA;LLUN000191-PA;LLUN000549-PA Reactome: R-HSA-9609690 HCMV Early Events 28 LLUN000039-PA;LLUN004789-PA;LLUN011179-PA;LLUN006353-PA;LLUN003553-PA;LLUN009062-PA;LLUN003438-PA;LLUN011766-PA;LLUN004100-PA;LLUN008374-PA;LLUN003209-PA;LLUN001860-PA;LLUN002581-PA;LLUN009963-PA;LLUN007825-PA;LLUN007599-PA;LLUN005292-PA;LLUN003554-PA;LLUN008923-PA;LLUN006723-PA;LLUN001776-PA;LLUN001322-PA;LLUN008894-PA;LLUN010831-PA;LLUN012529-PA;LLUN002707-PA;LLUN013269-PA;LLUN003240-PA KEGG: 00480+3.4.11.1 Glutathione metabolism 4 LLUN000082-PA;LLUN009324-PA;LLUN008962-PA;LLUN008963-PA MetaCyc: PWY-7900 Glycogen biosynthesis III (from alpha-maltose 1-phosphate) 6 LLUN006388-PA;LLUN003576-PA;LLUN009049-PA;LLUN009050-PA;LLUN002260-PA;LLUN003575-PA MetaCyc: PWY-7254 TCA cycle VII (acetate-producers) 9 LLUN012407-PA;LLUN011041-PA;LLUN012663-PA;LLUN008348-PA;LLUN012634-PA;LLUN001228-PA;LLUN000260-PA;LLUN000255-PA;LLUN005021-PA KEGG: 00534+2.4.2.26 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 1 LLUN011872-PA KEGG: 00130+2.1.1.222+2.1.1.64 Ubiquinone and other terpenoid-quinone biosynthesis 1 LLUN003684-PA Reactome: R-HSA-3928662 EPHB-mediated forward signaling 8 LLUN007325-PA;LLUN013020-PA;LLUN007070-PA;LLUN012841-PA;LLUN008044-PA;LLUN006122-PA;LLUN002885-PA;LLUN010670-PA KEGG: 00770+2.7.8.7 Pantothenate and CoA biosynthesis 1 LLUN006777-PA Reactome: R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 2 LLUN001786-PA;LLUN004788-PA Reactome: R-HSA-2871809 FCERI mediated Ca+2 mobilization 2 LLUN004972-PA;LLUN004409-PA KEGG: 00260+3.1.3.3 Glycine, serine and threonine metabolism 2 LLUN006711-PA;LLUN000062-PA Reactome: R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 1 LLUN011378-PA KEGG: 00565+3.1.3.4 Ether lipid metabolism 1 LLUN003443-PA KEGG: 00900+2.3.3.10 Terpenoid backbone biosynthesis 1 LLUN007815-PA MetaCyc: PWY-7177 UTP and CTP dephosphorylation II 1 LLUN000315-PA Reactome: R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 6 LLUN002616-PA;LLUN006125-PA;LLUN011466-PA;LLUN005530-PA;LLUN009748-PA;LLUN011465-PA Reactome: R-HSA-3878781 Glycogen storage disease type IV (GBE1) 1 LLUN002260-PA MetaCyc: PWY-7227 Adenosine deoxyribonucleotides de novo biosynthesis 7 LLUN006247-PA;LLUN012527-PA;LLUN001080-PA;LLUN000213-PA;LLUN011985-PA;LLUN012628-PA;LLUN008193-PA Reactome: R-HSA-9037629 Lewis blood group biosynthesis 13 LLUN007864-PA;LLUN012007-PA;LLUN011850-PA;LLUN004300-PA;LLUN009654-PA;LLUN006343-PA;LLUN006734-PA;LLUN005063-PA;LLUN009224-PA;LLUN007865-PA;LLUN010582-PA;LLUN004301-PA;LLUN007627-PA MetaCyc: PWY-6853 Ethylene biosynthesis II (microbes) 2 LLUN009954-PA;LLUN009509-PA KEGG: 00860+4.1.1.37 Porphyrin and chlorophyll metabolism 2 LLUN010075-PA;LLUN012709-PA Reactome: R-HSA-175474 Assembly Of The HIV Virion 1 LLUN005530-PA Reactome: R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 29 LLUN002998-PA;LLUN008342-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN009994-PA;LLUN004861-PA;LLUN006627-PA;LLUN006267-PA;LLUN009980-PA;LLUN002054-PA;LLUN003501-PA;LLUN005440-PA;LLUN006525-PA;LLUN008960-PA;LLUN012548-PA;LLUN005593-PA;LLUN005610-PA;LLUN004794-PA;LLUN004508-PA;LLUN013272-PA;LLUN003215-PA;LLUN004706-PA;LLUN005030-PA;LLUN010012-PA;LLUN008477-PA;LLUN003629-PA;LLUN002894-PA;LLUN000089-PA Reactome: R-HSA-434316 Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion 2 LLUN009047-PA;LLUN009048-PA MetaCyc: PWY-7799 Arg/N-end rule pathway (eukaryotic) 5 LLUN007836-PA;LLUN010557-PA;LLUN002815-PA;LLUN000170-PA;LLUN008126-PA KEGG: 00310+1.8.1.4 Lysine degradation 1 LLUN000029-PA KEGG: 00511+3.2.1.96 Other glycan degradation 1 LLUN008281-PA Reactome: R-HSA-196843 Vitamin B2 (riboflavin) metabolism 3 LLUN000051-PA;LLUN002130-PA;LLUN000319-PA Reactome: R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 6 LLUN011088-PA;LLUN008281-PA;LLUN006087-PA;LLUN008139-PA;LLUN005530-PA;LLUN004426-PA KEGG: 00970+6.1.1.5 Aminoacyl-tRNA biosynthesis 3 LLUN009588-PA;LLUN009127-PA;LLUN000051-PA Reactome: R-HSA-977225 Amyloid fiber formation 5 LLUN003449-PA;LLUN011108-PA;LLUN005530-PA;LLUN009875-PA;LLUN001957-PA MetaCyc: PWY-7375 Mrna capping I 3 LLUN010082-PA;LLUN011672-PA;LLUN004511-PA Reactome: R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 64 LLUN012390-PA;LLUN005586-PA;LLUN007812-PA;LLUN004193-PA;LLUN010052-PA;LLUN000494-PA;LLUN005442-PA;LLUN002390-PA;LLUN003780-PA;LLUN012611-PA;LLUN002560-PA;LLUN006512-PA;LLUN008530-PA;LLUN008357-PA;LLUN005594-PA;LLUN007100-PA;LLUN012076-PA;LLUN006093-PA;LLUN000493-PA;LLUN004402-PA;LLUN012053-PA;LLUN000856-PA;LLUN007972-PA;LLUN001675-PA;LLUN008597-PA;LLUN010350-PA;LLUN008152-PA;LLUN003033-PA;LLUN006098-PA;LLUN003515-PA;LLUN003524-PA;LLUN005084-PA;LLUN003497-PA;LLUN004909-PA;LLUN010136-PA;LLUN008995-PA;LLUN000340-PA;LLUN007563-PA;LLUN012333-PA;LLUN009774-PA;LLUN010358-PA;LLUN005530-PA;LLUN009998-PA;LLUN002787-PA;LLUN012474-PA;LLUN011304-PA;LLUN004837-PA;LLUN003577-PA;LLUN001670-PA;LLUN009131-PA;LLUN006863-PA;LLUN003373-PA;LLUN006279-PA;LLUN001569-PA;LLUN009419-PA;LLUN006179-PA;LLUN009177-PA;LLUN003745-PA;LLUN002287-PA;LLUN010153-PA;LLUN011174-PA;LLUN007733-PA;LLUN007661-PA;LLUN012495-PA Reactome: R-HSA-5579026 Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) 1 LLUN006656-PA KEGG: 00564+4.1.1.65 Glycerophospholipid metabolism 4 LLUN000568-PA;LLUN000263-PA;LLUN002860-PA;LLUN010169-PA KEGG: 00650+2.2.1.6 Butanoate metabolism 2 LLUN000551-PA;LLUN000044-PA Reactome: R-HSA-70895 Branched-chain amino acid catabolism 8 LLUN009332-PA;LLUN000312-PA;LLUN000092-PA;LLUN000533-PA;LLUN004841-PA;LLUN000029-PA;LLUN000314-PA;LLUN004291-PA Reactome: R-HSA-912631 Regulation of signaling by CBL 2 LLUN005530-PA;LLUN006897-PA KEGG: 00190+3.6.1.1 Oxidative phosphorylation 2 LLUN003630-PA;LLUN000272-PA Reactome: R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 8 LLUN005975-PA;LLUN004817-PA;LLUN002499-PA;LLUN009365-PA;LLUN001285-PA;LLUN000286-PA;LLUN001734-PA;LLUN006957-PA KEGG: 00051+4.2.1.47 Fructose and mannose metabolism 1 LLUN000234-PA KEGG: 00534+5.1.3.17 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 1 LLUN008728-PA MetaCyc: PWY-5136 Fatty acid beta-oxidation II (plant peroxisome) 5 LLUN000586-PA;LLUN008953-PA;LLUN007706-PA;LLUN000585-PA;LLUN011561-PA MetaCyc: PWY-1361 Benzoyl-coa degradation I (aerobic) 4 LLUN011561-PA;LLUN007706-PA;LLUN000586-PA;LLUN008953-PA Reactome: R-HSA-167287 HIV elongation arrest and recovery 16 LLUN011260-PA;LLUN007911-PA;LLUN011586-PA;LLUN009648-PA;LLUN008120-PA;LLUN002218-PA;LLUN009871-PA;LLUN001290-PA;LLUN003321-PA;LLUN011861-PA;LLUN001654-PA;LLUN009747-PA;LLUN007798-PA;LLUN000521-PA;LLUN009178-PA;LLUN001676-PA MetaCyc: PWY-5057 L-valine degradation II 1 LLUN012888-PA MetaCyc: PWY-6901 Superpathway of glucose and xylose degradation 6 LLUN012182-PA;LLUN000907-PA;LLUN007408-PA;LLUN013179-PA;LLUN000530-PA;LLUN010011-PA Reactome: R-HSA-9033241 Peroxisomal protein import 8 LLUN007391-PA;LLUN010953-PA;LLUN005530-PA;LLUN008395-PA;LLUN000578-PA;LLUN000759-PA;LLUN002757-PA;LLUN001796-PA Reactome: R-HSA-209543 p75NTR recruits signalling complexes 1 LLUN005530-PA Reactome: R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 31 LLUN000089-PA;LLUN002894-PA;LLUN011331-PA;LLUN005530-PA;LLUN004508-PA;LLUN004794-PA;LLUN005610-PA;LLUN005593-PA;LLUN003629-PA;LLUN008477-PA;LLUN003215-PA;LLUN005030-PA;LLUN010012-PA;LLUN004706-PA;LLUN013272-PA;LLUN006525-PA;LLUN005440-PA;LLUN003501-PA;LLUN012548-PA;LLUN008960-PA;LLUN010393-PA;LLUN011115-PA;LLUN012429-PA;LLUN008342-PA;LLUN002998-PA;LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN004861-PA;LLUN009994-PA;LLUN006627-PA Reactome: R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 37 LLUN000845-PA;LLUN007882-PA;LLUN006525-PA;LLUN006627-PA;LLUN009980-PA;LLUN004685-PA;LLUN012097-PA;LLUN008342-PA;LLUN005530-PA;LLUN000848-PA;LLUN002894-PA;LLUN005030-PA;LLUN013272-PA;LLUN003629-PA;LLUN005593-PA;LLUN004508-PA;LLUN008960-PA;LLUN012548-PA;LLUN005440-PA;LLUN003501-PA;LLUN009994-PA;LLUN004861-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN012273-PA;LLUN000089-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN008477-PA;LLUN005610-PA;LLUN004794-PA;LLUN004076-PA Reactome: R-HSA-446205 Synthesis of GDP-mannose 9 LLUN011806-PA;LLUN001188-PA;LLUN009771-PA;LLUN000108-PA;LLUN000168-PA;LLUN007218-PA;LLUN000176-PA;LLUN000564-PA;LLUN000532-PA KEGG: 00640+6.4.1.2 Propanoate metabolism 2 LLUN005463-PA;LLUN011458-PA MetaCyc: PWY-7380 Biotin biosynthesis from 8-amino-7-oxononanoate II 1 LLUN011577-PA MetaCyc: PWY-5958 Acridone alkaloid biosynthesis 2 LLUN000681-PA;LLUN012019-PA MetaCyc: PWY-6724 Starch degradation II 3 LLUN000671-PA;LLUN004023-PA;LLUN010451-PA MetaCyc: PWY-5855 Ubiquinol-7 biosynthesis (prokaryotic) 4 LLUN003684-PA;LLUN000136-PA;LLUN010266-PA;LLUN000584-PA Reactome: R-HSA-1266695 Interleukin-7 signaling 1 LLUN006897-PA MetaCyc: PWY-6946 Cholesterol degradation to androstenedione II (cholesterol dehydrogenase) 5 LLUN011561-PA;LLUN007706-PA;LLUN000585-PA;LLUN008953-PA;LLUN000586-PA MetaCyc: PWY-7996 Menaquinol-4 biosynthesis I 2 LLUN007379-PA;LLUN000579-PA Reactome: R-HSA-69231 Cyclin D associated events in G1 6 LLUN005530-PA;LLUN010517-PA;LLUN010602-PA;LLUN001565-PA;LLUN006111-PA;LLUN010156-PA KEGG: 00860+2.5.1.61 Porphyrin and chlorophyll metabolism 1 LLUN000561-PA MetaCyc: PWY-2161 Folate polyglutamylation 5 LLUN006558-PA;LLUN005962-PA;LLUN011129-PA;LLUN000209-PA;LLUN011200-PA KEGG: 00230+2.7.4.6 Purine metabolism 5 LLUN006247-PA;LLUN000213-PA;LLUN011985-PA;LLUN012628-PA;LLUN012527-PA KEGG: 00620+4.2.1.2 Pyruvate metabolism 3 LLUN012634-PA;LLUN005021-PA;LLUN000255-PA Reactome: R-HSA-6791462 TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P 4 LLUN010125-PA;LLUN006322-PA;LLUN000057-PA;LLUN000222-PA MetaCyc: PWY-5109 Fermentation to 2-methylbutanoate 5 LLUN000586-PA;LLUN008953-PA;LLUN000585-PA;LLUN007706-PA;LLUN011561-PA Reactome: R-HSA-8951671 RUNX3 regulates YAP1-mediated transcription 2 LLUN001900-PA;LLUN001899-PA MetaCyc: PWY-6620 Guanine and guanosine salvage 2 LLUN006332-PA;LLUN000578-PA KEGG: 00720+6.3.4.3 Carbon fixation pathways in prokaryotes 2 LLUN011200-PA;LLUN005962-PA MetaCyc: PWY-2161B Glutamate removal from folates 2 LLUN006148-PA;LLUN001010-PA Reactome: R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 24 LLUN001676-PA;LLUN010911-PA;LLUN009178-PA;LLUN000521-PA;LLUN008353-PA;LLUN007798-PA;LLUN009747-PA;LLUN001654-PA;LLUN002995-PA;LLUN011861-PA;LLUN003321-PA;LLUN001290-PA;LLUN002218-PA;LLUN009871-PA;LLUN009131-PA;LLUN008120-PA;LLUN001301-PA;LLUN012654-PA;LLUN010602-PA;LLUN009648-PA;LLUN011586-PA;LLUN007911-PA;LLUN011260-PA;LLUN001565-PA Reactome: R-HSA-70221 Glycogen breakdown (glycogenolysis) 9 LLUN004023-PA;LLUN000667-PA;LLUN000671-PA;LLUN013245-PA;LLUN001762-PA;LLUN010451-PA;LLUN000295-PA;LLUN011337-PA;LLUN008921-PA MetaCyc: PWY-7766 Heme b biosynthesis IV (Gram-positive bacteria) 2 LLUN010075-PA;LLUN012709-PA KEGG: 00760+2.4.2.19 Nicotinate and nicotinamide metabolism 1 LLUN000035-PA Reactome: R-HSA-879415 Advanced glycosylation endproduct receptor signaling 4 LLUN012000-PA;LLUN002516-PA;LLUN006087-PA;LLUN004112-PA MetaCyc: PWY-4981 L-proline biosynthesis II (from arginine) 2 LLUN000086-PA;LLUN000085-PA Reactome: R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 25 LLUN008779-PA;LLUN002475-PA;LLUN003240-PA;LLUN005759-PA;LLUN009115-PA;LLUN008923-PA;LLUN006723-PA;LLUN002707-PA;LLUN012645-PA;LLUN001322-PA;LLUN003209-PA;LLUN002581-PA;LLUN003554-PA;LLUN007825-PA;LLUN003553-PA;LLUN009062-PA;LLUN012527-PA;LLUN011766-PA;LLUN004100-PA;LLUN007151-PA;LLUN000039-PA;LLUN006974-PA;LLUN006353-PA;LLUN011179-PA;LLUN011046-PA MetaCyc: PWY-7357 Thiamine formation from pyrithiamine and oxythiamine (yeast) 1 LLUN000288-PA MetaCyc: PWY-7803 Trna splicing II 3 LLUN000972-PA;LLUN010906-PA;LLUN010101-PA MetaCyc: PWY-6174 Mevalonate pathway II (archaea) 3 LLUN006160-PA;LLUN006161-PA;LLUN007815-PA KEGG: 00053+5.1.3.22 Ascorbate and aldarate metabolism 1 LLUN000670-PA Reactome: R-HSA-202670 ERKs are inactivated 1 LLUN002516-PA Reactome: R-HSA-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression 2 LLUN001899-PA;LLUN001900-PA Reactome: R-HSA-75953 RNA Polymerase II Transcription Initiation 26 LLUN007911-PA;LLUN008159-PA;LLUN001565-PA;LLUN007705-PA;LLUN008198-PA;LLUN008863-PA;LLUN009871-PA;LLUN004030-PA;LLUN010602-PA;LLUN012654-PA;LLUN006269-PA;LLUN001301-PA;LLUN001654-PA;LLUN002995-PA;LLUN011861-PA;LLUN005474-PA;LLUN008199-PA;LLUN011583-PA;LLUN001290-PA;LLUN001676-PA;LLUN007987-PA;LLUN009178-PA;LLUN010911-PA;LLUN009851-PA;LLUN000521-PA;LLUN008353-PA MetaCyc: PWY-8088 Dipicolinate biosynthesis 1 LLUN012256-PA Reactome: R-HSA-70635 Urea cycle 6 LLUN000086-PA;LLUN008409-PA;LLUN000151-PA;LLUN002360-PA;LLUN000085-PA;LLUN000546-PA Reactome: R-HSA-9639288 Amino acids regulate mTORC1 17 LLUN005731-PA;LLUN002241-PA;LLUN004638-PA;LLUN002836-PA;LLUN005447-PA;LLUN005072-PA;LLUN007421-PA;LLUN012577-PA;LLUN012460-PA;LLUN005643-PA;LLUN007819-PA;LLUN010285-PA;LLUN006176-PA;LLUN012843-PA;LLUN012849-PA;LLUN005085-PA;LLUN006440-PA KEGG: 00195+7.1.2.2 Photosynthesis 5 LLUN005731-PA;LLUN006324-PA;LLUN001187-PA;LLUN000558-PA;LLUN002012-PA KEGG: 00520+3.2.1.52 Amino sugar and nucleotide sugar metabolism 6 LLUN008090-PA;LLUN007975-PA;LLUN010383-PA;LLUN009341-PA;LLUN007651-PA;LLUN003183-PA KEGG: 00790+4.6.1.17 Folate biosynthesis 1 LLUN010509-PA MetaCyc: PWY-6580 Phosphatidylinositol biosynthesis I (bacteria) 1 LLUN006316-PA MetaCyc: PWY-7851 Coenzyme A biosynthesis II (eukaryotic) 4 LLUN000037-PA;LLUN002593-PA;LLUN001090-PA;LLUN000524-PA KEGG: 00670+1.5.1.5+3.5.4.9 One carbon pool by folate 3 LLUN000777-PA;LLUN011200-PA;LLUN010882-PA MetaCyc: PWY-7783 Plasmalogen degradation 7 LLUN001410-PA;LLUN000563-PA;LLUN008580-PA;LLUN003919-PA;LLUN008242-PA;LLUN001370-PA;LLUN003536-PA Reactome: R-HSA-975578 Reactions specific to the complex N-glycan synthesis pathway 1 LLUN007876-PA MetaCyc: PWY-7111 Pyruvate fermentation to isobutanol (engineered) 4 LLUN000044-PA;LLUN000553-PA;LLUN012888-PA;LLUN000551-PA KEGG: 00500+3.6.1.9 Starch and sucrose metabolism 3 LLUN006214-PA;LLUN003890-PA;LLUN000110-PA KEGG: 00910+6.3.1.2 Nitrogen metabolism 4 LLUN002238-PA;LLUN000515-PA;LLUN000514-PA;LLUN002676-PA KEGG: 00564+3.1.1.7 Glycerophospholipid metabolism 1 LLUN007595-PA Reactome: R-HSA-8943723 Regulation of PTEN mRNA translation 2 LLUN005309-PA;LLUN009676-PA Reactome: R-HSA-211981 Xenobiotics 15 LLUN008827-PA;LLUN009959-PA;LLUN003034-PA;LLUN007586-PA;LLUN007455-PA;LLUN002933-PA;LLUN006044-PA;LLUN005716-PA;LLUN008224-PA;LLUN006887-PA;LLUN002934-PA;LLUN007844-PA;LLUN007846-PA;LLUN008771-PA;LLUN004756-PA KEGG: 00670+2.1.2.10 One carbon pool by folate 1 LLUN008929-PA Reactome: R-HSA-168325 Viral Messenger RNA Synthesis 18 LLUN001290-PA;LLUN003438-PA;LLUN004789-PA;LLUN011861-PA;LLUN008374-PA;LLUN001654-PA;LLUN000521-PA;LLUN001860-PA;LLUN009178-PA;LLUN001676-PA;LLUN007599-PA;LLUN001776-PA;LLUN013269-PA;LLUN008894-PA;LLUN007911-PA;LLUN012529-PA;LLUN010831-PA;LLUN009871-PA MetaCyc: PWY-7839 Lacto-series glycosphingolipids biosynthesis 1 LLUN004238-PA MetaCyc: PWY-6556 Pyrimidine ribonucleosides salvage II 1 LLUN012848-PA MetaCyc: PWY-7724 Icosapentaenoate biosynthesis III (8-desaturase, mammals) 18 LLUN003913-PA;LLUN011810-PA;LLUN005813-PA;LLUN003202-PA;LLUN001586-PA;LLUN009068-PA;LLUN001585-PA;LLUN011428-PA;LLUN008915-PA;LLUN001587-PA;LLUN002534-PA;LLUN003915-PA;LLUN003366-PA;LLUN004697-PA;LLUN004698-PA;LLUN002535-PA;LLUN000999-PA;LLUN011712-PA Reactome: R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 30 LLUN008960-PA;LLUN012548-PA;LLUN005440-PA;LLUN003501-PA;LLUN006525-PA;LLUN009994-PA;LLUN004861-PA;LLUN006627-PA;LLUN009980-PA;LLUN006267-PA;LLUN002054-PA;LLUN002998-PA;LLUN012429-PA;LLUN011115-PA;LLUN010393-PA;LLUN008342-PA;LLUN005530-PA;LLUN000089-PA;LLUN002894-PA;LLUN003215-PA;LLUN010012-PA;LLUN005030-PA;LLUN004706-PA;LLUN013272-PA;LLUN008477-PA;LLUN003629-PA;LLUN005610-PA;LLUN005593-PA;LLUN004508-PA;LLUN004794-PA Reactome: R-HSA-5687128 MAPK6/MAPK4 signaling 34 LLUN000089-PA;LLUN010012-PA;LLUN003215-PA;LLUN004706-PA;LLUN008477-PA;LLUN005309-PA;LLUN005610-PA;LLUN004794-PA;LLUN008960-PA;LLUN006122-PA;LLUN012548-PA;LLUN003501-PA;LLUN005440-PA;LLUN004861-PA;LLUN009994-PA;LLUN002054-PA;LLUN006267-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN005530-PA;LLUN002894-PA;LLUN013272-PA;LLUN005030-PA;LLUN003629-PA;LLUN009748-PA;LLUN005593-PA;LLUN004508-PA;LLUN006525-PA;LLUN006627-PA;LLUN009676-PA;LLUN009980-PA;LLUN008342-PA MetaCyc: PWY-5691 Urate conversion to allantoin I 3 LLUN007804-PA;LLUN009875-PA;LLUN012972-PA MetaCyc: PWY-8071 N-3-oxalyl-L-2,3-diaminopropanoate biosynthesis 1 LLUN000532-PA Reactome: R-HSA-5223345 Miscellaneous transport and binding events 1 LLUN006474-PA Reactome: R-HSA-3000178 ECM proteoglycans 3 LLUN013133-PA;LLUN000590-PA;LLUN004092-PA KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35 Butanoate metabolism 2 LLUN011561-PA;LLUN000586-PA Reactome: R-HSA-880009 Interconversion of 2-oxoglutarate and 2-hydroxyglutarate 3 LLUN000071-PA;LLUN010795-PA;LLUN000886-PA KEGG: 00561+2.3.1.274 Glycerolipid metabolism 1 LLUN005168-PA MetaCyc: PWY-3801 Sucrose degradation II (sucrose synthase) 2 LLUN009234-PA;LLUN000137-PA Reactome: R-HSA-5659996 RPIA deficiency: failed conversion of R5P to RU5P 2 LLUN007784-PA;LLUN000903-PA KEGG: 00983+1.17.4.1 Drug metabolism - other enzymes 2 LLUN001080-PA;LLUN008193-PA MetaCyc: PWY-7294 D-xylose degradation IV 2 LLUN007673-PA;LLUN000144-PA Reactome: R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 29 LLUN005030-PA;LLUN003215-PA;LLUN004706-PA;LLUN010012-PA;LLUN013272-PA;LLUN003629-PA;LLUN008477-PA;LLUN005610-PA;LLUN005593-PA;LLUN004794-PA;LLUN004508-PA;LLUN005530-PA;LLUN000089-PA;LLUN002894-PA;LLUN006111-PA;LLUN009994-PA;LLUN006627-PA;LLUN004861-PA;LLUN002054-PA;LLUN009980-PA;LLUN002998-PA;LLUN011115-PA;LLUN010393-PA;LLUN012429-PA;LLUN008342-PA;LLUN008960-PA;LLUN005440-PA;LLUN003501-PA;LLUN006525-PA MetaCyc: PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I 2 LLUN005541-PA;LLUN012034-PA KEGG: 00030+2.7.1.15 Pentose phosphate pathway 1 LLUN006228-PA KEGG: 00450+2.5.1.48 Selenocompound metabolism 1 LLUN000541-PA Reactome: R-HSA-2559586 DNA Damage/Telomere Stress Induced Senescence 1 LLUN010205-PA MetaCyc: PWY-6368 3-phosphoinositide degradation 3 LLUN011415-PA;LLUN008703-PA;LLUN003912-PA Reactome: R-HSA-193648 NRAGE signals death through JNK 3 LLUN001551-PA;LLUN004481-PA;LLUN003356-PA KEGG: 00983+2.7.4.6 Drug metabolism - other enzymes 5 LLUN006247-PA;LLUN012527-PA;LLUN011985-PA;LLUN012628-PA;LLUN000213-PA KEGG: 00052+3.2.1.22 Galactose metabolism 4 LLUN007044-PA;LLUN001202-PA;LLUN010776-PA;LLUN005205-PA KEGG: 00592+1.1.1.1 alpha-Linolenic acid metabolism 1 LLUN012888-PA MetaCyc: PWY-7544 Pyruvate to cytochrome bo oxidase electron transfer 1 LLUN000751-PA Reactome: R-HSA-499943 Interconversion of nucleotide di- and triphosphates 17 LLUN000827-PA;LLUN008193-PA;LLUN000660-PA;LLUN008895-PA;LLUN000315-PA;LLUN000547-PA;LLUN000764-PA;LLUN005171-PA;LLUN010665-PA;LLUN000213-PA;LLUN011011-PA;LLUN001080-PA;LLUN006609-PA;LLUN000531-PA;LLUN006247-PA;LLUN000163-PA;LLUN000522-PA KEGG: 00620+4.1.1.31 Pyruvate metabolism 1 LLUN000543-PA Reactome: R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 6 LLUN008395-PA;LLUN000578-PA;LLUN010402-PA;LLUN002757-PA;LLUN001208-PA;LLUN001796-PA KEGG: 00791+3.5.1.54+6.3.4.6 Atrazine degradation 1 LLUN001217-PA Reactome: R-HSA-4720475 Defective ALG3 causes ALG3-CDG (CDG-1d) 1 LLUN003653-PA Reactome: R-HSA-8849469 PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 1 LLUN005530-PA KEGG: 00020+1.8.1.4 Citrate cycle (TCA cycle) 1 LLUN000029-PA KEGG: 00250+6.3.5.5 Alanine, aspartate and glutamate metabolism 2 LLUN000049-PA;LLUN009630-PA MetaCyc: PWY-7953 UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing) 3 LLUN000040-PA;LLUN000042-PA;LLUN000097-PA KEGG: 00540+2.7.4.29 Lipopolysaccharide biosynthesis 1 LLUN006837-PA MetaCyc: PWY-4202 Arsenate detoxification I (mammalian) 2 LLUN000774-PA;LLUN000578-PA MetaCyc: PWY-7185 UTP and CTP dephosphorylation I 3 LLUN003082-PA;LLUN000322-PA;LLUN000315-PA MetaCyc: PWY-6366 D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis 1 LLUN009162-PA Reactome: R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 12 LLUN000404-PA;LLUN011163-PA;LLUN000563-PA;LLUN000692-PA;LLUN006020-PA;LLUN012819-PA;LLUN011433-PA;LLUN002154-PA;LLUN012760-PA;LLUN003498-PA;LLUN010205-PA;LLUN000062-PA MetaCyc: PWY-5103 L-isoleucine biosynthesis III 3 LLUN000551-PA;LLUN000553-PA;LLUN000044-PA Reactome: R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 8 LLUN007882-PA;LLUN000848-PA;LLUN005530-PA;LLUN012273-PA;LLUN000845-PA;LLUN012097-PA;LLUN004076-PA;LLUN004685-PA KEGG: 00514+2.4.1.255 Other types of O-glycan biosynthesis 3 LLUN000599-PA;LLUN013219-PA;LLUN003864-PA MetaCyc: PWY-5067 Glycogen biosynthesis II (from UDP-D-Glucose) 7 LLUN008754-PA;LLUN006388-PA;LLUN003576-PA;LLUN009049-PA;LLUN009050-PA;LLUN003575-PA;LLUN002260-PA Reactome: R-HSA-9610379 HCMV Late Events 17 LLUN006491-PA;LLUN013036-PA;LLUN008374-PA;LLUN005247-PA;LLUN003438-PA;LLUN007046-PA;LLUN004789-PA;LLUN007599-PA;LLUN001860-PA;LLUN013269-PA;LLUN012529-PA;LLUN008894-PA;LLUN010831-PA;LLUN001776-PA;LLUN005475-PA;LLUN005188-PA;LLUN002215-PA Reactome: R-HSA-389977 Post-chaperonin tubulin folding pathway 8 LLUN011766-PA;LLUN009062-PA;LLUN003733-PA;LLUN008923-PA;LLUN006353-PA;LLUN003240-PA;LLUN001580-PA;LLUN007825-PA Reactome: R-HSA-170968 Frs2-mediated activation 1 LLUN002516-PA Reactome: R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 6 LLUN005530-PA;LLUN000443-PA;LLUN000554-PA;LLUN004172-PA;LLUN011856-PA;LLUN001578-PA Reactome: R-HSA-877300 Interferon gamma signaling 3 LLUN011839-PA;LLUN003903-PA;LLUN003904-PA MetaCyc: PWY-6963 Ammonia assimilation cycle I 4 LLUN002238-PA;LLUN000515-PA;LLUN002676-PA;LLUN000514-PA MetaCyc: PWY-6714 L-rhamnose degradation III 1 LLUN000572-PA MetaCyc: PWY-8074 Kdo transfer to lipid IVA IV (P. putida) 1 LLUN000527-PA Reactome: R-HSA-9635465 Suppression of apoptosis 1 LLUN002516-PA KEGG: 00030+2.7.6.1 Pentose phosphate pathway 3 LLUN004009-PA;LLUN004011-PA;LLUN009897-PA Reactome: R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 1 LLUN008164-PA Reactome: R-HSA-195253 Degradation of beta-catenin by the destruction complex 32 LLUN006525-PA;LLUN008342-PA;LLUN006627-PA;LLUN009980-PA;LLUN011378-PA;LLUN002894-PA;LLUN005530-PA;LLUN005593-PA;LLUN004508-PA;LLUN013272-PA;LLUN005030-PA;LLUN003629-PA;LLUN003501-PA;LLUN005440-PA;LLUN008960-PA;LLUN012548-PA;LLUN002998-PA;LLUN011115-PA;LLUN012429-PA;LLUN010393-PA;LLUN009994-PA;LLUN004861-PA;LLUN006111-PA;LLUN006267-PA;LLUN002054-PA;LLUN000089-PA;LLUN005610-PA;LLUN004794-PA;LLUN003215-PA;LLUN010012-PA;LLUN004706-PA;LLUN008477-PA KEGG: 00350+2.6.1.1 Tyrosine metabolism 1 LLUN009219-PA KEGG: 00254+6.4.1.2 Aflatoxin biosynthesis 2 LLUN005463-PA;LLUN011458-PA KEGG: 00520+5.3.1.9 Amino sugar and nucleotide sugar metabolism 1 LLUN000137-PA KEGG: 00030+1.1.1.44 Pentose phosphate pathway 3 LLUN006639-PA;LLUN000245-PA;LLUN012568-PA MetaCyc: PWY-6313 Serotonin degradation 1 LLUN012888-PA MetaCyc: PWY-5856 Ubiquinol-9 biosynthesis (prokaryotic) 4 LLUN010266-PA;LLUN000584-PA;LLUN000136-PA;LLUN003684-PA MetaCyc: PWY-1861 Formaldehyde assimilation II (assimilatory RuMP Cycle) 14 LLUN010699-PA;LLUN007784-PA;LLUN002938-PA;LLUN006322-PA;LLUN002937-PA;LLUN000832-PA;LLUN000903-PA;LLUN000222-PA;LLUN010125-PA;LLUN000534-PA;LLUN011949-PA;LLUN000057-PA;LLUN000906-PA;LLUN010698-PA MetaCyc: PWY-6385 Peptidoglycan biosynthesis III (mycobacteria) 4 LLUN002437-PA;LLUN000674-PA;LLUN000041-PA;LLUN011710-PA KEGG: 00720+2.3.3.8 Carbon fixation pathways in prokaryotes 1 LLUN007878-PA MetaCyc: PWY-7734 Quinoxaline-2-carboxylate biosynthesis 1 LLUN004035-PA Reactome: R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 2 LLUN005530-PA;LLUN006111-PA Reactome: R-HSA-164843 2-LTR circle formation 1 LLUN004049-PA Reactome: R-HSA-9636467 Blockage of phagosome acidification 1 LLUN004638-PA Reactome: R-HSA-4641263 Regulation of FZD by ubiquitination 1 LLUN005530-PA KEGG: 00680+2.6.1.52 Methane metabolism 3 LLUN012010-PA;LLUN000776-PA;LLUN011489-PA KEGG: 00720+6.2.1.5 Carbon fixation pathways in prokaryotes 7 LLUN012993-PA;LLUN007879-PA;LLUN011264-PA;LLUN007880-PA;LLUN008350-PA;LLUN007878-PA;LLUN003300-PA KEGG: 00550+3.4.16.4 Peptidoglycan biosynthesis 1 LLUN000207-PA KEGG: 00770+2.1.2.11 Pantothenate and CoA biosynthesis 2 LLUN007480-PA;LLUN011706-PA Reactome: R-HSA-8934593 Regulation of RUNX1 Expression and Activity 5 LLUN009676-PA;LLUN009498-PA;LLUN005309-PA;LLUN009497-PA;LLUN009496-PA MetaCyc: PWY-6614 Tetrahydrofolate biosynthesis 2 LLUN010048-PA;LLUN000281-PA Reactome: R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency 62 LLUN006512-PA;LLUN008530-PA;LLUN002560-PA;LLUN012333-PA;LLUN009998-PA;LLUN005530-PA;LLUN010358-PA;LLUN009774-PA;LLUN008357-PA;LLUN004193-PA;LLUN010136-PA;LLUN005586-PA;LLUN007812-PA;LLUN004909-PA;LLUN012390-PA;LLUN002390-PA;LLUN003780-PA;LLUN012611-PA;LLUN007563-PA;LLUN005442-PA;LLUN010052-PA;LLUN000494-PA;LLUN007275-PA;LLUN000340-PA;LLUN008995-PA;LLUN003745-PA;LLUN003033-PA;LLUN009419-PA;LLUN009177-PA;LLUN001569-PA;LLUN008152-PA;LLUN010350-PA;LLUN008597-PA;LLUN006279-PA;LLUN003497-PA;LLUN005084-PA;LLUN003524-PA;LLUN012495-PA;LLUN003515-PA;LLUN007661-PA;LLUN011174-PA;LLUN007733-PA;LLUN002287-PA;LLUN006098-PA;LLUN010153-PA;LLUN004402-PA;LLUN000493-PA;LLUN006093-PA;LLUN012076-PA;LLUN004837-PA;LLUN011304-PA;LLUN007100-PA;LLUN005594-PA;LLUN012474-PA;LLUN002787-PA;LLUN003373-PA;LLUN001675-PA;LLUN006863-PA;LLUN007972-PA;LLUN001670-PA;LLUN000856-PA;LLUN012053-PA KEGG: 00051+4.1.2.13 Fructose and mannose metabolism 3 LLUN000906-PA;LLUN011949-PA;LLUN000832-PA KEGG: 00630+1.1.1.60 Glyoxylate and dicarboxylate metabolism 1 LLUN000312-PA KEGG: 00240+2.4.2.9 Pyrimidine metabolism 1 LLUN000773-PA Reactome: R-HSA-6814848 Glycerophospholipid catabolism 1 LLUN012430-PA KEGG: 00040+5.3.1.5 Pentose and glucuronate interconversions 1 LLUN005109-PA MetaCyc: PWY-6342 Noradrenaline and adrenaline degradation 1 LLUN012888-PA Reactome: R-HSA-5625740 RHO GTPases activate PKNs 3 LLUN007485-PA;LLUN002936-PA;LLUN005092-PA MetaCyc: PWY-5080 Very long chain fatty acid biosynthesis I 18 LLUN011712-PA;LLUN000999-PA;LLUN004697-PA;LLUN003366-PA;LLUN004698-PA;LLUN003915-PA;LLUN002535-PA;LLUN001585-PA;LLUN003202-PA;LLUN001586-PA;LLUN009068-PA;LLUN011428-PA;LLUN008915-PA;LLUN002534-PA;LLUN001587-PA;LLUN003913-PA;LLUN005813-PA;LLUN011810-PA KEGG: 00220+4.3.2.1 Arginine biosynthesis 2 LLUN002360-PA;LLUN000546-PA MetaCyc: PWY-5189 Tetrapyrrole biosynthesis II (from glycine) 4 LLUN010957-PA;LLUN011442-PA;LLUN000561-PA;LLUN005927-PA MetaCyc: PWY-7187 Pyrimidine deoxyribonucleotides de novo biosynthesis II 12 LLUN006214-PA;LLUN003890-PA;LLUN006605-PA;LLUN011985-PA;LLUN012628-PA;LLUN000110-PA;LLUN005171-PA;LLUN010665-PA;LLUN012527-PA;LLUN000213-PA;LLUN006247-PA;LLUN000163-PA MetaCyc: PWY-43 Putrescine biosynthesis II 1 LLUN000189-PA Reactome: R-HSA-1253288 Downregulation of ERBB4 signaling 1 LLUN005530-PA MetaCyc: PWY-7053 Docosahexaenoate biosynthesis I (lower eukaryotes) 2 LLUN009068-PA;LLUN011810-PA Reactome: R-HSA-2871796 FCERI mediated MAPK activation 3 LLUN007704-PA;LLUN004409-PA;LLUN002516-PA KEGG: 00520+2.7.7.9 Amino sugar and nucleotide sugar metabolism 1 LLUN009234-PA Reactome: R-HSA-162594 Early Phase of HIV Life Cycle 1 LLUN008802-PA Reactome: R-HSA-5173214 O-glycosylation of TSR domain-containing proteins 14 LLUN008322-PA;LLUN001369-PA;LLUN004632-PA;LLUN008626-PA;LLUN004801-PA;LLUN012955-PA;LLUN003060-PA;LLUN011341-PA;LLUN004503-PA;LLUN005564-PA;LLUN003505-PA;LLUN001391-PA;LLUN004313-PA;LLUN003200-PA KEGG: 00480+1.8.1.7 Glutathione metabolism 1 LLUN000660-PA KEGG: 00240+2.7.4.6 Pyrimidine metabolism 5 LLUN006247-PA;LLUN012527-PA;LLUN011985-PA;LLUN012628-PA;LLUN000213-PA Reactome: R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 1 LLUN000364-PA Reactome: R-HSA-8948700 Competing endogenous RNAs (ceRNAs) regulate PTEN translation 2 LLUN009676-PA;LLUN005309-PA Reactome: R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 1 LLUN002128-PA MetaCyc: PWY-6409 Pyoverdine I biosynthesis 1 LLUN008772-PA Reactome: R-HSA-112409 RAF-independent MAPK1/3 activation 1 LLUN002516-PA KEGG: 00550+2.7.8.13 Peptidoglycan biosynthesis 2 LLUN000042-PA;LLUN011947-PA Reactome: R-HSA-74259 Purine catabolism 5 LLUN000916-PA;LLUN006214-PA;LLUN009431-PA;LLUN009904-PA;LLUN009750-PA Reactome: R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 2 LLUN011726-PA;LLUN008959-PA MetaCyc: PWY-6642 (R)-cysteate degradation 1 LLUN009219-PA MetaCyc: PWY-5531 3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic) 2 LLUN012709-PA;LLUN010075-PA MetaCyc: PWY-5394 Betalamic acid biosynthesis 1 LLUN000709-PA KEGG: 00720+4.1.1.31 Carbon fixation pathways in prokaryotes 1 LLUN000543-PA KEGG: 00980+1.1.1.1 Metabolism of xenobiotics by cytochrome P450 1 LLUN012888-PA MetaCyc: PWY-7675 Kdo transfer to lipid IVA II (Haemophilus) 1 LLUN000527-PA KEGG: 00740+2.7.1.26+2.7.7.2 Riboflavin metabolism 1 LLUN000051-PA MetaCyc: PWY-8072 Alanine racemization 3 LLUN000915-PA;LLUN000131-PA;LLUN005700-PA MetaCyc: PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) 5 LLUN000040-PA;LLUN000549-PA;LLUN000191-PA;LLUN000097-PA;LLUN000042-PA Reactome: R-HSA-3656253 Defective EXT1 causes exostoses 1, TRPS2 and CHDS 2 LLUN004191-PA;LLUN002060-PA Reactome: R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 18 LLUN011861-PA;LLUN002995-PA;LLUN001654-PA;LLUN001290-PA;LLUN009178-PA;LLUN010911-PA;LLUN001676-PA;LLUN008353-PA;LLUN007798-PA;LLUN000521-PA;LLUN007911-PA;LLUN004511-PA;LLUN001565-PA;LLUN010082-PA;LLUN009871-PA;LLUN010602-PA;LLUN012654-PA;LLUN001301-PA KEGG: 00500+2.7.1.1 Starch and sucrose metabolism 2 LLUN003849-PA;LLUN005483-PA Reactome: R-HSA-203615 eNOS activation 1 LLUN011786-PA Reactome: R-HSA-1296061 HCN channels 1 LLUN007598-PA MetaCyc: PWY-7559 Glutathione degradation (DUG pathway 3 LLUN001088-PA;LLUN000741-PA;LLUN000193-PA Reactome: R-HSA-9665251 Resistance of ERBB2 KD mutants to lapatinib 2 LLUN008416-PA;LLUN008205-PA KEGG: 00710+5.3.1.6 Carbon fixation in photosynthetic organisms 2 LLUN007784-PA;LLUN000903-PA KEGG: 00300+2.3.1.117 Lysine biosynthesis 1 LLUN000168-PA Reactome: R-HSA-427652 Sodium-coupled phosphate cotransporters 1 LLUN007940-PA KEGG: 00860+1.16.3.1 Porphyrin and chlorophyll metabolism 1 LLUN006496-PA KEGG: 00513+3.2.1.52 Various types of N-glycan biosynthesis 6 LLUN007975-PA;LLUN008090-PA;LLUN010383-PA;LLUN007651-PA;LLUN009341-PA;LLUN003183-PA Reactome: R-HSA-8940973 RUNX2 regulates osteoblast differentiation 4 LLUN009497-PA;LLUN009496-PA;LLUN009498-PA;LLUN002516-PA KEGG: 00020+6.2.1.5 Citrate cycle (TCA cycle) 7 LLUN012993-PA;LLUN008350-PA;LLUN003300-PA;LLUN007878-PA;LLUN007879-PA;LLUN011264-PA;LLUN007880-PA Reactome: R-HSA-70268 Pyruvate metabolism 2 LLUN012656-PA;LLUN000029-PA Reactome: R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 1 LLUN005530-PA KEGG: 00540+3.5.1.108 Lipopolysaccharide biosynthesis 1 LLUN000038-PA Reactome: R-HSA-197264 Nicotinamide salvaging 6 LLUN012146-PA;LLUN009089-PA;LLUN000264-PA;LLUN005370-PA;LLUN000613-PA;LLUN007526-PA KEGG: 00500+2.4.1.11 Starch and sucrose metabolism 1 LLUN008754-PA KEGG: 00250+4.3.2.2 Alanine, aspartate and glutamate metabolism 1 LLUN002429-PA Reactome: R-HSA-74217 Purine salvage 4 LLUN009730-PA;LLUN008942-PA;LLUN004537-PA;LLUN000036-PA MetaCyc: PWY-6531 Mannitol cycle 1 LLUN006839-PA KEGG: 00510+2.4.1.68 N-Glycan biosynthesis 1 LLUN007876-PA KEGG: 00071+2.3.1.16 Fatty acid degradation 1 LLUN000585-PA MetaCyc: PWY-7049 Icosapentaenoate biosynthesis II (6-desaturase, mammals) 2 LLUN009068-PA;LLUN011810-PA Reactome: R-HSA-9022692 Regulation of MECP2 expression and activity 3 LLUN005309-PA;LLUN011839-PA;LLUN009676-PA KEGG: 00190+2.7.4.1 Oxidative phosphorylation 1 LLUN000771-PA Reactome: R-HSA-189483 Heme degradation 1 LLUN010186-PA KEGG: 00061+1.1.1.100 Fatty acid biosynthesis 2 LLUN005169-PA;LLUN000184-PA Reactome: R-HSA-933541 TRAF6 mediated IRF7 activation 3 LLUN004172-PA;LLUN010444-PA;LLUN008644-PA MetaCyc: PWY-7573 GDP-mycosamine biosynthesis 1 LLUN000234-PA Reactome: R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 1 LLUN010175-PA Reactome: R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 4 LLUN001786-PA;LLUN004788-PA;LLUN001565-PA;LLUN010602-PA Reactome: R-HSA-1660499 Synthesis of PIPs at the plasma membrane 5 LLUN011979-PA;LLUN006224-PA;LLUN007852-PA;LLUN011415-PA;LLUN006897-PA MetaCyc: PWY-7159 3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent) 5 LLUN010075-PA;LLUN012136-PA;LLUN000224-PA;LLUN012709-PA;LLUN008764-PA KEGG: 00480+6.3.2.2 Glutathione metabolism 2 LLUN007915-PA;LLUN009565-PA KEGG: 00600+3.2.1.22 Sphingolipid metabolism 4 LLUN005205-PA;LLUN001202-PA;LLUN010776-PA;LLUN007044-PA MetaCyc: PWY-7347 Sucrose biosynthesis III 1 LLUN000137-PA KEGG: 00220+3.5.1.14 Arginine biosynthesis 1 LLUN010503-PA KEGG: 00260+1.1.1.1 Glycine, serine and threonine metabolism 1 LLUN012888-PA Reactome: R-HSA-9648895 Response of EIF2AK1 (HRI) to heme deficiency 1 LLUN007275-PA MetaCyc: PWY-7295 L-arabinose degradation IV 2 LLUN007673-PA;LLUN000144-PA Reactome: R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 13 LLUN007599-PA;LLUN009131-PA;LLUN012404-PA;LLUN001860-PA;LLUN010831-PA;LLUN008894-PA;LLUN012529-PA;LLUN008374-PA;LLUN000821-PA;LLUN013269-PA;LLUN004789-PA;LLUN003438-PA;LLUN001776-PA MetaCyc: PWY-7193 Pyrimidine ribonucleosides salvage I 1 LLUN012848-PA KEGG: 00430+2.3.2.2 Taurine and hypotaurine metabolism 3 LLUN001088-PA;LLUN000741-PA;LLUN000193-PA Reactome: R-HSA-5683826 Surfactant metabolism 2 LLUN007799-PA;LLUN004537-PA MetaCyc: PWY-4261 Glycerol degradation I 5 LLUN010207-PA;LLUN008655-PA;LLUN000668-PA;LLUN000536-PA;LLUN005350-PA Reactome: R-HSA-4085377 SUMOylation of SUMOylation proteins 10 LLUN007599-PA;LLUN001860-PA;LLUN008374-PA;LLUN013269-PA;LLUN008894-PA;LLUN012529-PA;LLUN010831-PA;LLUN003438-PA;LLUN001776-PA;LLUN004789-PA KEGG: 00970+6.1.1.3 Aminoacyl-tRNA biosynthesis 5 LLUN009401-PA;LLUN000521-PA;LLUN011021-PA;LLUN010923-PA;LLUN002921-PA KEGG: 00780+1.1.1.100 Biotin metabolism 2 LLUN000184-PA;LLUN005169-PA KEGG: 00901+4.1.1.105 Indole alkaloid biosynthesis 1 LLUN000568-PA MetaCyc: PWY-6545 Pyrimidine deoxyribonucleotides de novo biosynthesis III 13 LLUN006214-PA;LLUN006605-PA;LLUN003890-PA;LLUN012628-PA;LLUN011985-PA;LLUN008193-PA;LLUN000110-PA;LLUN005171-PA;LLUN012527-PA;LLUN001080-PA;LLUN000213-PA;LLUN003082-PA;LLUN006247-PA KEGG: 00982+2.5.1.18 Drug metabolism - cytochrome P450 2 LLUN008487-PA;LLUN008086-PA Reactome: R-HSA-8876725 Protein methylation 3 LLUN013136-PA;LLUN004272-PA;LLUN009338-PA