Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_046464842.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway"
XP_046476479.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_046486506.1	12	MetaCyc: PWY-6978;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-5873	"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_046486448.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046477475.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046477597.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046473228.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046468885.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046486534.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046479990.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046467670.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_046468901.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046469301.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110381;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_046475766.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_046465899.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046486705.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046479289.1	24	Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G-protein activation";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_046475538.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_046489952.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_046473231.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046482036.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046487275.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046485540.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_046474998.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046473189.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046473514.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046482212.1	11	Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_046492740.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046468965.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046471732.1	5	KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3	"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_046465146.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046492989.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046467155.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism"
XP_046473936.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046479356.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046488958.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_046467125.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046474415.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046475059.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046464777.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046478813.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_046475447.1	7	KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4	"Valine, leucine and isoleucine degradation";"Peroxisomal protein import";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Geraniol degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies"
XP_046466311.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046476935.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_046479668.1	2	KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_046485723.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046480244.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046475474.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-438066	"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Long-term potentiation";"Ion transport by P-type ATPases";"RAF activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_046471172.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway"
XP_046489576.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046473699.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273;MetaCyc: PWY-922	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I"
XP_046466189.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_046482548.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046480670.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046472437.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046483632.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046471702.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046488242.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046491311.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046475444.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-936837	"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"RAF activation";"Long-term potentiation";"Ion transport by P-type ATPases"
XP_046481637.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277	"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex"
XP_046470260.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046485709.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_046473251.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046479116.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046476657.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046486621.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-141430	"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_046484646.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046487329.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
XP_046470730.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046486363.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_046486015.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_046483305.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046489356.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046479221.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046469142.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046466382.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046474761.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046470546.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_046470968.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046476309.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_046492455.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046489697.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711	"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events"
XP_046478841.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046472833.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046491765.1	6	Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8951664;Reactome: R-HSA-201722	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation";"Formation of the beta-catenin:TCF transactivating complex"
XP_046482581.1	10	Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-6361	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_046477332.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046468848.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046487491.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Neutrophil degranulation";"ROS and RNS production in phagocytes"
XP_046486546.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-1234158	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"FOXO-mediated transcription of cell death genes";"Attenuation phase";"RORA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_046478222.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046475527.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination"
XP_046471640.1	42	Reactome: R-HSA-5693565;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-2299718;Reactome: R-HSA-977225;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-9610379;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-212300;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-5693571;Reactome: R-HSA-5334118;Reactome: R-HSA-1912408;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-606279	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"Condensation of Prophase Chromosomes";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"HCMV Late Events";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"DNA methylation";"Pre-NOTCH Transcription and Translation";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Meiotic recombination";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046481116.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046489102.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046468674.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046483260.1	4	MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726	"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation"
XP_046493168.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046485220.1	18	MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801	"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PS"
XP_046489597.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046492702.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_046492963.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046481865.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046489936.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046476178.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046483542.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation"
XP_046487676.1	7	Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;MetaCyc: PWY-6351;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the early endosome membrane"
XP_046470480.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_046470556.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046478257.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046485928.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046478873.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_046484826.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692	"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity"
XP_046488761.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_046475566.1	7	Reactome: R-HSA-1483213;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-7886	"Synthesis of PE";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_046470455.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046479284.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046491703.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046476399.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046474414.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046474277.1	5	KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32	"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis"
XP_046473424.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046485339.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046490846.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046484208.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046478996.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046485386.1	7	Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_046486009.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046492771.1	12	Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270	"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046476687.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_046478330.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-8939236	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_046492619.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046470871.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046468577.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046467030.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046488906.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046471699.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046487128.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046466836.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046473870.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046481115.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046477298.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046488114.1	10	MetaCyc: PWY-6365;MetaCyc: PWY-6366;Reactome: R-HSA-1855204;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.159;Reactome: R-HSA-983231	"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Factors involved in megakaryocyte development and platelet production"
XP_046482006.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_046486261.1	13	Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52	"Hyaluronan uptake and degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_046478509.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046477950.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046475382.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046493173.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046473033.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046492541.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046489841.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046474014.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811434	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046477974.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_046471245.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046482198.1	20	Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-110320	"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH"
XP_046475411.1	4	Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258	"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_046475393.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-5578775	"RAF activation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis"
XP_046474128.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3301854	"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly"
XP_046490573.1	4	KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_046468758.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_046485249.1	18	Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783	"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation"
XP_046478338.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046480395.1	15	Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174084	"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_046469276.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046484449.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_046487770.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046483128.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046473541.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046484909.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046478988.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046486623.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046474910.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046474640.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046465246.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046468522.1	13	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway"
XP_046476061.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046479468.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046467097.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046482611.1	16	Reactome: R-HSA-3134963;Reactome: R-HSA-5603037;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-975138;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-975155;Reactome: R-HSA-209543;Reactome: R-HSA-975871;Reactome: R-HSA-1810476;Reactome: R-HSA-5602498;Reactome: R-HSA-166058	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR5)";"Interleukin-1 signaling";"ER-Phagosome pathway";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 dependent cascade initiated on endosome";"p75NTR recruits signalling complexes";"MyD88 cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_046478007.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046474435.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046492385.1	6	Reactome: R-HSA-5368286;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046488159.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_046476983.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046491137.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046465180.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046485904.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_046479133.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis"
XP_046471515.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046473582.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_046481076.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046464831.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_046469095.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046475328.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046490919.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046466454.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046488817.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046489137.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046482678.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046487164.1	5	Reactome: R-HSA-446199;Reactome: R-HSA-4755579;Reactome: R-HSA-193048;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94	"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis"
XP_046485018.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046476003.1	6	KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-6364	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_046472639.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046478476.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046491511.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128	"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling"
XP_046489962.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_046489300.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046483963.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046488704.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_046483779.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046485665.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_046465191.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046491436.1	6	KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609978	"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALT can cause Galactosemia"
XP_046490671.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046493145.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_046486445.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_046480217.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046481010.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046466884.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046486861.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_046466589.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_046488124.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046465591.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_046475624.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046485634.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046486108.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046480203.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046484149.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046482887.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_046473559.1	11	Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-69166	"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate"
XP_046478587.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046486105.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_046475322.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046489818.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046476256.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_046493057.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046476131.1	17	Reactome: R-HSA-196780;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744	"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Jadomycin biosynthesis";"Pyruvate metabolism";"Candicidin biosynthesis";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation"
XP_046481533.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046466143.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_046465331.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046486474.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_046482017.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046484499.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046487653.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046488620.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"Circadian Clock"
XP_046488539.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745	"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_046466591.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046464731.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046485632.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046480060.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046482622.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_046492772.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_046492050.1	10	MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7344	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Galactose metabolism";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis"
XP_046485209.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_046476757.1	3	KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_046482132.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046489724.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046465062.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_046486154.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046486183.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046468989.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_046486870.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046471856.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046468245.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_046480218.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046493041.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_046487051.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_046472142.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046470248.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046470697.1	5	MetaCyc: PWY-2161B;KEGG: 00510+2.4.1.142;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;KEGG: 00513+2.4.1.142	"Glutamate removal from folates";"N-Glycan biosynthesis";"Folate biosynthesis";"Neutrophil degranulation";"Various types of N-glycan biosynthesis"
XP_046480572.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046481820.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046467421.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046479864.1	11	Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-5689880;Reactome: R-HSA-167161;Reactome: R-HSA-3214847	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"Ub-specific processing proteases";"HIV Transcription Initiation";"HATs acetylate histones"
XP_046485142.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046486066.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046469111.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046487045.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046464893.1	4	Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26	"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_046485993.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046485513.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-1989781	"Endogenous sterols";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"PPARA activates gene expression"
XP_046465084.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_046469217.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046484096.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_046491483.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046478821.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046481742.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046474475.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046485967.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046485464.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin"
XP_046469038.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046488879.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046469636.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_046488157.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_046475038.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046481675.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-192823	"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Viral mRNA Translation"
XP_046485817.1	16	Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-9009391	"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"RET signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"Signaling by SCF-KIT";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling"
XP_046485132.1	57	Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257	"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN"
XP_046482004.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046478314.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046487159.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_046487248.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046488301.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_046468049.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046487404.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046484649.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046475141.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046479985.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046465289.1	2	Reactome: R-HSA-442660;Reactome: R-HSA-352230	"Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane"
XP_046474030.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046482580.1	10	MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554	"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_046483124.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046484214.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046481826.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046484063.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_046481209.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
XP_046467480.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-428890	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling"
XP_046483956.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046466089.1	12	MetaCyc: PWY-5133;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5132;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1	"Colupulone and cohumulone biosynthesis";"Propanoate metabolism";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism"
XP_046477735.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046468683.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046483816.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_046472874.1	14	Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783	"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Ether lipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Plasmalogen degradation"
XP_046485103.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_046490714.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_046480409.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_046465623.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_046487381.1	5	KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism"
XP_046491303.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_046480747.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046485579.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046466417.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046490342.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046484508.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046491462.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046484444.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046482688.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_046476945.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046473412.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_046473849.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046492625.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046478482.1	8	Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Activation of RAC1";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046480837.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046469330.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046483060.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046465039.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_046480207.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046465063.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_046470375.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046480481.1	3	Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis"
XP_046470327.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_046485882.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-2151201;Reactome: R-HSA-3214847	"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis";"HATs acetylate histones"
XP_046470842.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046489470.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046479121.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046468756.1	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046493175.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046466075.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046488290.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046468690.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_046481473.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-6992;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-3861	"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II"
XP_046478487.1	14	Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_046487095.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046472384.1	7	KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6277	"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_046473568.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_046473366.1	7	MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753	"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_046484536.1	6	Reactome: R-HSA-8939211;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16	"ESR-mediated signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway"
XP_046473278.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046487526.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_046489893.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046469010.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046465171.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046479648.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_046464768.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046484695.1	182	Reactome: R-HSA-69231;Reactome: R-HSA-937042;Reactome: R-HSA-2559580;Reactome: R-HSA-917937;Reactome: R-HSA-5358346;Reactome: R-HSA-5689901;Reactome: R-HSA-2173791;Reactome: R-HSA-983168;Reactome: R-HSA-975956;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-72689;Reactome: R-HSA-182971;Reactome: R-HSA-174490;Reactome: R-HSA-211733;Reactome: R-HSA-6782135;Reactome: R-HSA-162588;Reactome: R-HSA-2173796;Reactome: R-HSA-5656121;Reactome: R-HSA-5689603;Reactome: R-HSA-5654732;Reactome: R-HSA-174048;Reactome: R-HSA-72702;Reactome: R-HSA-532668;Reactome: R-HSA-6781827;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-349425;Reactome: R-HSA-975163;Reactome: R-HSA-5696397;Reactome: R-HSA-175474;Reactome: R-HSA-110320;Reactome: R-HSA-1799339;Reactome: R-HSA-187577;Reactome: R-HSA-2173795;Reactome: R-HSA-179409;Reactome: R-HSA-72649;Reactome: R-HSA-8876493;Reactome: R-HSA-6791226;Reactome: R-HSA-937039;Reactome: R-HSA-5610783;Reactome: R-HSA-168927;Reactome: R-HSA-69541;Reactome: R-HSA-5205685;Reactome: R-HSA-6804756;Reactome: R-HSA-156902;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-8856825;Reactome: R-HSA-180534;Reactome: R-HSA-5685942;Reactome: R-HSA-209560;Reactome: R-HSA-69017;Reactome: R-HSA-2173788;Reactome: R-HSA-5689880;Reactome: R-HSA-912631;Reactome: R-HSA-174154;Reactome: R-HSA-5362768;Reactome: R-HSA-936440;Reactome: R-HSA-174184;Reactome: R-HSA-5696395;Reactome: R-HSA-8948747;Reactome: R-HSA-2122948;Reactome: R-HSA-937072;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-209543;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-9633012;Reactome: R-HSA-917729;Reactome: R-HSA-5654726;Reactome: R-HSA-975957;Reactome: R-HSA-5656169;Reactome: R-HSA-8939902;Reactome: R-HSA-6807004;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-9636383;Reactome: R-HSA-6781823;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-9615710;Reactome: R-HSA-5610785;Reactome: R-HSA-6783310;Reactome: R-HSA-450408;Reactome: R-HSA-2644606;Reactome: R-HSA-5654727;Reactome: R-HSA-5357956;Reactome: R-HSA-180585;Reactome: R-HSA-5696394;Reactome: R-HSA-201681;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-9013507;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-9613829;Reactome: R-HSA-1236974;Reactome: R-HSA-5675482;Reactome: R-HSA-1253288;Reactome: R-HSA-2565942;Reactome: R-HSA-8852276;Reactome: R-HSA-5689896;Reactome: R-HSA-5607761;Reactome: R-HSA-1295596;Reactome: R-HSA-6804757;Reactome: R-HSA-5689877;Reactome: R-HSA-5357905;Reactome: R-HSA-3322077;Reactome: R-HSA-9010553;Reactome: R-HSA-2559585;Reactome: R-HSA-2672351;Reactome: R-HSA-4641263;Reactome: R-HSA-205043;Reactome: R-HSA-5654733;Reactome: R-HSA-2871837;Reactome: R-HSA-5693565;Reactome: R-HSA-8948751;Reactome: R-HSA-1236382;Reactome: R-HSA-8856828;Reactome: R-HSA-6804760;Reactome: R-HSA-9637628;Reactome: R-HSA-936964;Reactome: R-HSA-8951664;Reactome: R-HSA-5693607;Reactome: R-HSA-8875360;Reactome: R-HSA-8849469;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9645460;Reactome: R-HSA-72706;Reactome: R-HSA-8863795;Reactome: R-HSA-2559582;Reactome: R-HSA-68827;Reactome: R-HSA-72695;Reactome: R-HSA-8866652;Reactome: R-HSA-975110;Reactome: R-HSA-110312;Reactome: R-HSA-975144;Reactome: R-HSA-9033241;Reactome: R-HSA-156827;Reactome: R-HSA-937041;Reactome: R-HSA-5675221;Reactome: R-HSA-3134975;Reactome: R-HSA-5655862;Reactome: R-HSA-2122947;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-8866654;Reactome: R-HSA-2691232;Reactome: R-HSA-192823;Reactome: R-HSA-2979096;Reactome: R-HSA-168638;Reactome: R-HSA-9646399;Reactome: R-HSA-1169091;Reactome: R-HSA-3769402;Reactome: R-HSA-3785653;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-901032;Reactome: R-HSA-9013973;Reactome: R-HSA-1358803;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-6782210;Reactome: R-HSA-195253;Reactome: R-HSA-450321;Reactome: R-HSA-1234176;Reactome: R-HSA-168928;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858	"Cyclin D associated events in G1";"IRAK2 mediated activation of TAK1 complex";"Oxidative Stress Induced Senescence";"Iron uptake and transport";"Hedgehog ligand biogenesis";"Metalloprotease DUBs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"Formation of a pool of free 40S subunits";"EGFR downregulation";"Membrane binding and targetting of GAG proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dual incision in TC-NER";"Budding and maturation of HIV virion";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Translesion synthesis by POLI";"UCH proteinases";"Negative regulation of FGFR3 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Ribosomal scanning and start codon recognition";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of the E3 ubiquitin ligase COP1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Assembly Of The HIV Virion";"Translesion Synthesis by POLH";"SRP-dependent cotranslational protein targeting to membrane";"SCF(Skp2)-mediated degradation of p27/p21";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"APC-Cdc20 mediated degradation of Nek2A";"Translation initiation complex formation";"InlA-mediated entry of Listeria monocytogenes into host cells";"Major pathway of rRNA processing in the nucleolus and cytosol";"IRAK1 recruits IKK complex";"Degradation of GLI2 by the proteasome";"TICAM1, RIP1-mediated IKK complex recruitment";"Stabilization of p53";"Pink/Parkin Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Peptide chain elongation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Cargo recognition for clathrin-mediated endocytosis";"Vpu mediated degradation of CD4";"HDR through Homologous Recombination (HRR)";"NF-kB is activated and signals survival";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of TGF-beta receptor signaling";"Ub-specific processing proteases";"Regulation of signaling by CBL";"APC/C:Cdc20 mediated degradation of Securin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulators of DDX58/IFIH1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Formation of Incision Complex in GG-NER";"Regulation of PTEN localization";"Activated NOTCH1 Transmits Signal to the Nucleus";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"p75NTR recruits signalling complexes";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of FGFR1 signaling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Termination of translesion DNA synthesis";"Regulation of RUNX2 expression and activity";"Negative regulation of MET activity";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"Prevention of phagosomal-lysosomal fusion";"Formation of TC-NER Pre-Incision Complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Late endosomal microautophagy";"GLI3 is processed to GLI3R by the proteasome";"Fanconi Anemia Pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of FGFR2 signaling";"TNFR1-induced NFkappaB signaling pathway";"Vif-mediated degradation of APOBEC3G";"DNA Damage Recognition in GG-NER";"TCF dependent signaling in response to WNT";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Degradation of AXIN";"Chaperone Mediated Autophagy";"ER-Phagosome pathway";"Regulation of necroptotic cell death";"Downregulation of ERBB4 signaling";"Regulation of PLK1 Activity at G2/M Transition";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ovarian tumor domain proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Spry regulation of FGF signaling";"Regulation of TP53 Degradation";"Josephin domain DUBs";"Regulation of TNFR1 signaling";"Glycogen synthesis";"Regulation of expression of SLITs and ROBOs";"Oncogene Induced Senescence";"Stimuli-sensing channels";"Regulation of FZD by ubiquitination";"NRIF signals cell death from the nucleus";"Negative regulation of FGFR4 signaling";"FCERI mediated NF-kB activation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of PTEN stability and activity";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Clathrin-mediated endocytosis";"Regulation of TP53 Activity through Methylation";"Modulation by Mtb of host immune system";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Neddylation";"Processing of DNA double-strand break ends";"InlB-mediated entry of Listeria monocytogenes into host cell";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Alpha-protein kinase 1 signaling pathway";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Downregulation of ERBB2 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"CDT1 association with the CDC6:ORC:origin complex";"Formation of the ternary complex, and subsequently, the 43S complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Translesion synthesis by REV1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Peroxisomal protein import";"L13a-mediated translational silencing of Ceruloplasmin expression";"IKK complex recruitment mediated by RIP1";"Negative regulation of MAPK pathway";"Regulation of innate immune responses to cytosolic DNA";"Translesion synthesis by POLK";"NOTCH1 Intracellular Domain Regulates Transcription";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"E3 ubiquitin ligases ubiquitinate target proteins";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Viral mRNA Translation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOD1/2 Signaling Pathway";"Aggrephagy";"Activation of NF-kappaB in B cells";"Deactivation of the beta-catenin transactivating complex";"Myoclonic epilepsy of Lafora";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"ER Quality Control Compartment (ERQC)";"TICAM1-dependent activation of IRF3/IRF7";"Downregulation of ERBB2:ERBB3 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Degradation of beta-catenin by the destruction complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity"
XP_046482288.1	29	Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-5696395;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-3371511;Reactome: R-HSA-6783310;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693616	"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HSF1 activation";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046483603.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_046490393.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046472381.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046489301.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046486773.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046467815.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046472038.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046466475.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046473472.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046483031.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046489297.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046467840.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046475218.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046466805.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046482571.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046473329.1	6	KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism"
XP_046481183.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826	"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis"
XP_046471779.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046474622.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_046468238.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046492699.1	7	KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22	"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_046486045.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046485334.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046487174.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046488005.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046487633.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046491230.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046474725.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_046479578.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046470059.1	8	Reactome: R-HSA-6804757;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827	"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_046488701.1	13	MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-6728	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle"
XP_046490847.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046480635.1	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_046488300.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_046491519.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046468457.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046485649.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046479896.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046465773.1	6	MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-6898;MetaCyc: PWY-6907;Reactome: R-HSA-196819	"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism"
XP_046469408.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046475226.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046466509.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046493154.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046467213.1	4	Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046492486.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046486011.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046491684.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_046468847.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046489456.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_046468279.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-2892247;Reactome: R-HSA-2892245;Reactome: R-HSA-8986944;Reactome: R-HSA-452723;Reactome: R-HSA-6785807	"Deactivation of the beta-catenin transactivating complex";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Transcriptional Regulation by MECP2";"Transcriptional regulation of pluripotent stem cells";"Interleukin-4 and Interleukin-13 signaling"
XP_046478508.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_046471067.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046473702.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046486061.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046484890.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046491593.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046486218.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046472209.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046485359.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046490036.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046485935.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046479238.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046481934.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_046474788.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state"
XP_046466885.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046479020.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046484301.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046474600.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885	"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins"
XP_046475005.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046483891.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs"
XP_046478900.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-159236	"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046469696.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046490910.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046487037.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046482174.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046486875.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046490572.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_046480284.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046480480.1	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_046465294.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_046474894.1	9	Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736	"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors"
XP_046464809.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046483437.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046477598.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046492082.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046468907.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046482583.1	10	Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-6361	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_046485436.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046485666.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046478325.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231	"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046468881.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046488076.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046485824.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046479852.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046465585.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046466841.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046484822.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046465008.1	7	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-373753;Reactome: R-HSA-203641;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-8856828	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Nephrin family interactions";"NOSTRIN mediated eNOS trafficking";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"Clathrin-mediated endocytosis"
XP_046482789.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046487975.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046482199.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046475334.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046484936.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046478896.1	33	Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4551638	"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins"
XP_046484999.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046475778.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046478815.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_046492902.1	9	KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11	"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidylinositol signaling system"
XP_046466992.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046486821.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046485622.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046488943.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_046481148.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046489951.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_046473719.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway"
XP_046477550.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046483330.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046468500.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046485944.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_046469730.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046482208.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046478278.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_046481127.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046465566.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046475630.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046468642.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046468250.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046489269.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046473255.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046487288.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_046488277.1	18	Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557	"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis"
XP_046474371.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_046479449.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046467543.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046486301.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_046467227.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046478081.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046473181.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046491709.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_046479542.1	7	Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-606279;Reactome: R-HSA-5696394	"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"UCH proteinases";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER"
XP_046483323.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046483079.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046475504.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837	"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"RAF activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases"
XP_046469404.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046488587.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046473336.1	6	KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23	"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_046478269.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046478527.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046474473.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046464921.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_046484094.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_046485711.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046489604.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046479631.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046467458.1	5	Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_046471570.1	11	Reactome: R-HSA-74259;MetaCyc: PWY-6999;MetaCyc: PWY-6596;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6608;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-6606;MetaCyc: PWY-6538;MetaCyc: PWY-5695;MetaCyc: PWY-5497	"Purine catabolism";"Theophylline degradation";"Adenosine nucleotides degradation I";"Purine metabolism";"Guanosine nucleotides degradation III";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Purine nucleobases degradation II (anaerobic)"
XP_046470563.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046485293.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_046470442.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046479676.1	12	Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-9010553	"Translation initiation complex formation";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs"
XP_046492767.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_046470757.1	13	MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-202433;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;Reactome: R-HSA-2029485;KEGG: 04070+3.1.4.11;Reactome: R-HSA-9027277;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-2424491	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Inositol phosphate metabolism";"FCERI mediated MAPK activation";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling"
XP_046466587.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046472435.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046487148.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-1169408	"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism"
XP_046489145.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046481138.1	14	Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-380259;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257	"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Loss of Nlp from mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion"
XP_046488255.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046468845.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_046478484.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046478556.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046465696.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046479772.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046483293.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_046480634.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_046478753.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046475642.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046479014.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046470568.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046468068.1	13	KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7198	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_046470262.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046479951.1	12	MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation"
XP_046491787.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046490694.1	12	KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5132;MetaCyc: PWY-5133	"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis"
XP_046492492.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046473527.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_046490544.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_046468702.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_046465560.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_046467698.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046468415.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955	"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation"
XP_046481061.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046485340.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046480179.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046466384.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046471400.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046476979.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046470077.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046466285.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_046481632.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046473254.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046484847.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_046478153.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_046466801.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046485323.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046484983.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046467199.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_046464872.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046486576.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046479627.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046469113.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046478881.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046486535.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046480649.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046469365.1	10	MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Galactose metabolism"
XP_046485429.1	22	MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7592;MetaCyc: PWY-7049;MetaCyc: PWY-6958;KEGG: 00062+4.2.1.134;Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7053;MetaCyc: PWY-7724	"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046477963.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_046469499.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046485930.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046490228.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046476343.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_046485455.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046466295.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046476153.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046491553.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046485515.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-1989781	"Endogenous sterols";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"PPARA activates gene expression"
XP_046468954.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_046483288.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
XP_046489995.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_046487356.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514;Reactome: R-HSA-70171	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis"
XP_046472441.1	32	Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-72163	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway"
XP_046493167.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046477965.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_046465625.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_046488670.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046472385.1	7	MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277;Reactome: R-HSA-73817	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_046479472.1	11	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046484124.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046483846.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6	"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation"
XP_046477984.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433	"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046476923.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046465086.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_046489406.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_046467821.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046483630.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046468517.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046487421.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046466855.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_046484169.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046467076.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046486062.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046477734.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046470148.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046472120.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_046485442.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_046474782.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046466280.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-8853884	"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX"
XP_046466003.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046480181.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046490680.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046470642.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_046481974.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_046465531.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046479562.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046471349.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_046470080.1	16	Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-164939;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"WNT5A-dependent internalization of FZD4";"Nef mediated downregulation of CD28 cell surface expression";"Clathrin-mediated endocytosis"
XP_046466416.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046471040.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046467064.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_046474708.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046465647.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046476400.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046493410.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_046465988.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046484605.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046492049.1	10	Reactome: R-HSA-70370;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2	"Galactose catabolism";"D-galactose detoxification";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_046490682.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046473225.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046483841.1	20	MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7337	"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_046482680.1	17	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-176187	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"G2/M DNA damage checkpoint";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress"
XP_046488261.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046471942.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046466609.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420	"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi"
XP_046481624.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046482629.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046492609.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_046469965.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046471530.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046470771.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046484518.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046470473.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046488590.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_046468339.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-1655829	"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046488877.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046476299.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_046479769.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_046470132.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046481963.1	12	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Macroautophagy";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046468809.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046468304.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046471620.1	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_046475503.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046472183.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_046480468.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_046475771.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PG";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA"
XP_046479104.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046481467.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046489264.1	6	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-8876198	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"RAB GEFs exchange GTP for GDP on RABs"
XP_046481993.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046465614.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_046484809.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046483952.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046486795.1	4	MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate"
XP_046481341.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046468090.1	13	MetaCyc: PWY-7226;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-6545	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_046475435.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955	"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Long-term potentiation";"Ion transport by P-type ATPases";"RAF activation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_046473224.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046492583.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046491686.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_046468817.1	6	KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22	"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions"
XP_046490169.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046476962.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046486573.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046476195.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_046485127.1	4	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_046465616.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_046488324.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_046490372.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046488729.1	7	Reactome: R-HSA-70635;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-31;MetaCyc: PWY-4984	"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Canavanine degradation";"Urea cycle"
XP_046471476.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_046487258.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046479165.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046484114.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_046466179.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046467211.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046485901.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046489661.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046483922.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046481478.1	11	KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-3861;MetaCyc: PWY-882;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-7456	"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation"
XP_046466177.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046473947.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046471841.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046489472.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046489629.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_046465392.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046468240.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046487818.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046493105.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046468666.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III"
XP_046488089.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046484335.1	20	MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7858	"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II"
XP_046472193.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046481040.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046467949.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046471037.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046488752.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046472872.1	14	Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803	"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046490385.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046472433.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046484808.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046468623.1	7	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation"
XP_046473379.1	7	MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753	"UMP biosynthesis II";"UMP biosynthesis III";"Drug metabolism - other enzymes";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_046489314.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046466787.1	12	KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476	"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Rho GTPase cycle";"DCC mediated attractive signaling";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"G alpha (q) signalling events"
XP_046475072.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-6798695	"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Neutrophil degranulation"
XP_046482883.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046486053.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046484300.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046492725.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046469110.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046485172.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046480214.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046475028.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046468533.1	8	MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_046478512.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046477509.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-9615017	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_046465795.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046477309.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046486123.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046489172.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_046466124.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046470870.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046478903.1	7	Reactome: R-HSA-5578999;MetaCyc: PWY-7255;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-6840	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis"
XP_046490546.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_046469755.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046480086.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046471305.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism"
XP_046474973.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046475360.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046470617.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046476414.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046492698.1	7	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_046479917.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046473065.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling"
XP_046490672.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046477073.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046466373.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046466308.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046475836.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046492598.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046472873.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Ether lipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism"
XP_046487203.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046485934.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046479902.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_046478020.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046480543.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_046485707.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_046475002.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_046491961.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046488903.1	30	Reactome: R-HSA-5610780;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-2644606;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-1170546;Reactome: R-HSA-68949;Reactome: R-HSA-2644607;Reactome: R-HSA-187577;Reactome: R-HSA-69231;Reactome: R-HSA-2871837;Reactome: R-HSA-917937;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2122947	"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Prolactin receptor signaling";"Orc1 removal from chromatin";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation";"Iron uptake and transport";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046474199.1	29	Reactome: R-HSA-6804756;Reactome: R-HSA-69541;Reactome: R-HSA-5693568;Reactome: R-HSA-6804760;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-6803204;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-6803207;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-3371453;Reactome: R-HSA-349425;Reactome: R-HSA-912446;Reactome: R-HSA-69473;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942	"Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Methylation";"Human immunodeficiency virus 1 infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway";"Relaxin signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human cytomegalovirus infection";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of HSF1-mediated heat shock response";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"G2/M DNA damage checkpoint";"PI3K-Akt signaling pathway";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Human papillomavirus infection";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)"
XP_046476672.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_046475007.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046486943.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046476804.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046468918.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046478346.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046479146.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046484240.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046469497.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_046467477.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046489046.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046481532.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046489469.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046492788.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046476470.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046470457.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046476059.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046492744.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046491479.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046485027.1	11	MetaCyc: PWY-7821;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9	"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism"
XP_046469117.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046482284.1	57	Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764	"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling"
XP_046470769.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046488690.1	4	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-8849175	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism"
XP_046473451.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_046493260.1	18	MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Ether lipid metabolism"
XP_046470671.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046471788.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046483959.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046490650.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046471665.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046474208.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046466433.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046481042.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_046468329.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_046472344.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_046489768.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046471730.1	7	Reactome: R-HSA-196757;Reactome: R-HSA-1474151;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3	"Metabolism of folate and pterines";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"Folate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"One carbon pool by folate"
XP_046472814.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046486463.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046486036.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046489856.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046483249.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_046490957.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046484204.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046470900.1	7	Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Packaging Of Telomere Ends"
XP_046489924.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046491989.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046477955.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046476530.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_046473695.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046480667.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046492751.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046487431.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_046491594.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046488013.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046468423.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046491501.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Thermogenesis"
XP_046486557.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459	"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046487048.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046470483.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046480369.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046467857.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_046480516.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046489880.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_046489508.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046469370.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_046476632.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046467628.1	17	Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-9616222;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-111448;Reactome: R-HSA-113501;Reactome: R-HSA-2559585;Reactome: R-HSA-69231;Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-2559580;Reactome: R-HSA-6804114;Reactome: R-HSA-1912408;Reactome: R-HSA-1362300;Reactome: R-HSA-69656	"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of granulopoiesis";"G0 and Early G1";"G1/S-Specific Transcription";"Activation of NOXA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oncogene Induced Senescence";"Cyclin D associated events in G1";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Oxidative Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Pre-NOTCH Transcription and Translation";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046465873.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_046481980.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046492535.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046492633.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046483732.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046471058.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046474914.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046465473.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_046491288.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046484133.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_046468521.1	13	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928662	"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"PI3K-Akt signaling pathway";"EPHB-mediated forward signaling"
XP_046486922.1	5	KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)"
XP_046481492.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_046471158.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_046472771.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046466600.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046479320.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046471498.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046466502.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046490186.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046478786.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046479928.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046472826.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_046488548.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046469747.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046475664.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_046487160.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_046482541.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046480576.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046483947.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_046474623.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_046468021.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046492199.1	3	KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation"
XP_046474262.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_046467415.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046489498.1	9	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046484880.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046477785.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046465187.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046490095.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046475559.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046472387.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046465383.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046480069.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046470930.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046464723.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046491996.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046464769.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046475942.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046482014.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046486067.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046479183.1	4	Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_046480418.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046490197.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046484163.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046468968.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_046469089.1	16	Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519	"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression"
XP_046465674.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046480844.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Choline catabolism";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046484938.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046479017.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046479358.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation";"Neutrophil degranulation"
XP_046469892.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046491199.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046483254.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_046464871.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046493235.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046474940.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046471308.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046492670.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046492791.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046470082.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046489788.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046475628.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046472887.1	14	KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409	"Ether lipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_046472769.1	7	KEGG: 00550+2.7.8.13;MetaCyc: PWY-6471;MetaCyc: PWY-5265;MetaCyc: PWY-6470;Reactome: R-HSA-4549356;Reactome: R-HSA-446193;KEGG: 00510+2.7.8.15	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_046489658.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_046476963.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046468643.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046471299.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_046490542.1	8	Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)"
XP_046471923.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6794361;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins";"Neutrophil degranulation"
XP_046476599.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046475627.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046484829.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation"
XP_046486796.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108	"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis"
XP_046488307.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046473926.1	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046478386.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_046481843.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_046488023.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046473404.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046471312.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046482757.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_046467962.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046481417.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046474314.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046477459.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046484825.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944	"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2"
XP_046486691.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046488047.1	7	MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-6596;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-5695	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Purine metabolism";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Inosine 5'-phosphate degradation"
XP_046485512.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046486320.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_046479522.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046479286.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046486255.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_046471279.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-5620924;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-1632852;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Intraflagellar transport";"RHO GTPases Activate Formins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Macroautophagy";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046473856.1	8	Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_046466251.1	17	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6790901	"Viral mRNA Translation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol"
XP_046473470.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046486509.1	12	MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-6978	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II"
XP_046478088.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046479200.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046476118.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_046484146.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046474852.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046492773.1	12	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046490980.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046488158.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046466377.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_046476909.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046487261.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046483532.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046485637.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046484553.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_046482153.1	8	MetaCyc: PWY-6609;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179	"Adenine and adenosine salvage III";"Surfactant metabolism";"Purine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I"
XP_046472829.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046465393.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046483126.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046481077.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_046479100.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046470263.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046472158.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046483087.1	8	KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-6609	"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Surfactant metabolism";"Adenine and adenosine salvage III"
XP_046476574.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_046470538.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046489489.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_046489089.1	3	Reactome: R-HSA-9639288;Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Amino acids regulate mTORC1";"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_046469577.1	8	Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046465181.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046471583.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046465081.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_046488199.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046466761.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046484248.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046474947.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046464844.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway"
XP_046486113.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046471438.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046488015.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046486561.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593	"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity"
XP_046465283.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Glycerophospholipid metabolism";"Neurotransmitter clearance"
XP_046474786.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_046468012.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046474210.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046487457.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046469509.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046469466.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046468652.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178	"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans"
XP_046470150.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046473288.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway"
XP_046469563.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_046469278.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046480245.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046488901.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_046481479.1	11	MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-6992;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7456	"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Mannitol degradation II";"Beta-(1,4)-mannan degradation"
XP_046479030.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046474707.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046465044.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046492622.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_046492608.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_046488656.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046493357.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046477743.1	13	KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-7384	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_046491084.1	13	MetaCyc: PWY-7226;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046472343.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_046466191.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_046480859.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046467813.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046475720.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_046465190.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046487171.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases"
XP_046473457.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046474038.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation"
XP_046493412.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046476533.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046467118.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046490370.1	14	Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-113418	"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex"
XP_046472132.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046464841.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_046487263.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046480739.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis"
XP_046476348.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_046464715.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_046470241.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046485414.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046471961.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_046489313.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046491654.1	30	Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-2564830;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Cytosolic iron-sulfur cluster assembly";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_046469906.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046488705.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046478738.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046481724.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046483290.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription"
XP_046476732.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_046480896.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046488818.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046480249.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046470490.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046474256.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_046477178.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046467040.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046485656.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_046474502.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046465036.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046492387.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_046480497.1	7	Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-983231;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Regulation of PTEN gene transcription"
XP_046482995.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046481472.1	11	MetaCyc: PWY-6992;MetaCyc: PWY-7586;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-3861;MetaCyc: PWY-7456;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916	"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)"
XP_046469371.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_046486539.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046466716.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046468649.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046475389.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046486790.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046473552.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_046484171.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046481885.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-9609690	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events"
XP_046477630.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046479318.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046485257.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046476293.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046476869.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046487196.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046486832.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_046488183.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046480429.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046466255.1	31	MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-8012;MetaCyc: PWYG-321;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-8049;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWY-7858;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-6799;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;Reactome: R-HSA-199220;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-7663	"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Pederin biosynthesis";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Gondoate biosynthesis (anaerobic)"
XP_046484160.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046487629.1	16	Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-9018519;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-5693616	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046490065.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_046472912.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_046475291.1	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
XP_046473798.1	44	Reactome: R-HSA-3371453;Reactome: R-HSA-881907;Reactome: R-HSA-2559582;Reactome: R-HSA-170968;Reactome: R-HSA-2029482;Reactome: R-HSA-9634638;Reactome: R-HSA-9627069;Reactome: R-HSA-198753;Reactome: R-HSA-162658;Reactome: R-HSA-5654727;Reactome: R-HSA-982772;Reactome: R-HSA-444257;Reactome: R-HSA-5673001;Reactome: R-HSA-5654733;Reactome: R-HSA-5654726;Reactome: R-HSA-5674135;Reactome: R-HSA-375165;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-8940973;Reactome: R-HSA-6811558;Reactome: R-HSA-112409;Reactome: R-HSA-6802952;Reactome: R-HSA-445144;Reactome: R-HSA-2559585;Reactome: R-HSA-2871796;Reactome: R-HSA-5674499;Reactome: R-HSA-5654732;Reactome: R-HSA-5668599;Reactome: R-HSA-8943724;Reactome: R-HSA-450341;Reactome: R-HSA-1295596;Reactome: R-HSA-5663213;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-74749;Reactome: R-HSA-9635465;Reactome: R-HSA-879415;Reactome: R-HSA-8939211;Reactome: R-HSA-6802948;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-456926;Reactome: R-HSA-202670	"Regulation of HSF1-mediated heat shock response";"Gastrin-CREB signalling pathway via PKC and MAPK";"Senescence-Associated Secretory Phenotype (SASP)";"Frs2-mediated activation";"Regulation of actin dynamics for phagocytic cup formation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of the apoptosome activity";"ERK/MAPK targets";"Golgi Cisternae Pericentriolar Stack Reorganization";"Negative regulation of FGFR2 signaling";"Growth hormone receptor signaling";"RSK activation";"RAF/MAP kinase cascade";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR1 signaling";"MAP2K and MAPK activation";"NCAM signaling for neurite out-growth";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"RUNX2 regulates osteoblast differentiation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF-independent MAPK1/3 activation";"Signaling by BRAF and RAF fusions";"Signal transduction by L1";"Oncogene Induced Senescence";"FCERI mediated MAPK activation";"Negative feedback regulation of MAPK pathway";"Negative regulation of FGFR3 signaling";"RHO GTPases Activate NADPH Oxidases";"Regulation of PTEN gene transcription";"Activation of the AP-1 family of transcription factors";"Spry regulation of FGF signaling";"RHO GTPases Activate WASPs and WAVEs";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Signal attenuation";"Suppression of apoptosis";"Advanced glycosylation endproduct receptor signaling";"ESR-mediated signaling";"Signaling by high-kinase activity BRAF mutants";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"ERKs are inactivated"
XP_046492996.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_046479768.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046491411.1	17	Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167200;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167158;KEGG: 04658+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167287	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"T cell receptor signaling pathway";"Formation of the HIV-1 Early Elongation Complex";"Th1 and Th2 cell differentiation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery"
XP_046491202.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046475348.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046486054.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046466562.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_046488714.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation"
XP_046483476.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046466355.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_046467233.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046480821.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046470486.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046474266.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_046474453.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046491963.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046487776.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046473718.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046485072.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046467039.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046482802.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341	"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)"
XP_046483294.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling"
XP_046474727.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046478539.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_046478492.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046475804.1	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7185;Reactome: R-HSA-499943;MetaCyc: PWY-7176	"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis"
XP_046477380.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_046472429.1	17	Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135	"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER"
XP_046490024.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046473819.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046466182.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_046475638.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046483932.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_046467038.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046481385.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046487090.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046476938.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046466435.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046479795.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046490662.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046491425.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046484926.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046488820.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046477313.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046491521.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046471935.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046491094.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046473335.1	6	KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_046492602.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046478488.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091	"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching"
XP_046489305.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_046469288.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046475794.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-383280	"Generic Transcription Pathway";"PPARA activates gene expression";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway"
XP_046489209.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_046483574.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046471751.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046490088.1	3	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046475284.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046487890.1	11	KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4	"Ether lipid metabolism";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Sphingolipid metabolism"
XP_046490837.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_046487963.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046472347.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046489155.1	8	KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1	"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_046488833.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046467700.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046472095.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046477976.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046484720.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046464895.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_046487053.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046467126.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling by Hippo";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046484123.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046477749.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046476158.1	57	Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408	"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_046472249.1	3	KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685	"Purine metabolism";"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species"
XP_046478824.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_046492261.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046485406.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046479956.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046487961.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046487086.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046465123.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_046493133.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_046469791.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_046490814.1	9	Reactome: R-HSA-9608290;Reactome: R-HSA-110329;Reactome: R-HSA-9630221;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-9608287;Reactome: R-HSA-110331	"Defective MUTYH substrate processing";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective MUTYH substrate binding";"Cleavage of the damaged purine"
XP_046492361.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046478875.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046474896.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_046475437.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046470286.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_046466545.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046487729.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046477105.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_046484327.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046478920.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_046467856.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_046466313.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046478477.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046474890.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_046492058.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_046491705.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_046483245.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_046473289.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395	"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER"
XP_046472267.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046474970.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046490553.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046477759.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046477876.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_046469659.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_046469102.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681	"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT"
XP_046473951.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046488540.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_046483251.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_046475172.1	4	KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2	"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_046491369.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046483967.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046468706.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046484389.1	6	Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2	"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Cristae formation";"Mitochondrial protein import";"ATP biosynthesis";"Oxidative phosphorylation"
XP_046471093.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-3781	"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)"
XP_046466108.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_046483046.1	18	MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7221;MetaCyc: PWY-7224	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage"
XP_046478474.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046476035.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Choline catabolism";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046482490.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046479013.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046485360.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_046478423.1	3	Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801	"Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)"
XP_046488724.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046478337.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046489662.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046476916.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046470750.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046493324.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_046466935.1	12	Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-1251985;Reactome: R-HSA-75893;Reactome: R-HSA-2691232;Reactome: R-HSA-193692;Reactome: R-HSA-2894862	"Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Nuclear signaling by ERBB4";"TNF signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046466561.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_046483027.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046478586.1	15	Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348	"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex"
XP_046465755.1	7	KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;MetaCyc: PWY-7158;Reactome: R-HSA-8964208;Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1	"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine metabolism"
XP_046465345.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046488366.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046482194.1	20	Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-176187	"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress"
XP_046487672.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_046468960.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046471219.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046482572.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046464816.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_046479672.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046469727.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046472636.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046470553.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046478479.1	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046478146.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046469213.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-73930	"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_046480239.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046479441.1	33	KEGG: 00830+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00260+1.1.1.1;KEGG: 00625+1.1.1.1;KEGG: 00350+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00680+1.1.1.284;MetaCyc: PWY-7111;KEGG: 00592+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-6587;MetaCyc: PWY-5057;KEGG: 00010+1.1.1.1;KEGG: 00980+1.1.1.1;KEGG: 00071+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-5486;MetaCyc: PWY-7118;MetaCyc: PWY-6333;MetaCyc: PWY-7013;MetaCyc: PWY-5076;MetaCyc: PWY-5079;MetaCyc: PWY-6871;MetaCyc: PWY-6802;MetaCyc: PWY-1801;MetaCyc: PWY-7798;MetaCyc: PWY-6313;MetaCyc: PWY-5078;Reactome: R-HSA-71384;MetaCyc: PWY-5751;MetaCyc: PWY-6342	"Retinol metabolism";"Pyruvate fermentation to ethanol I";"Glycine, serine and threonine metabolism";"Chloroalkane and chloroalkene degradation";"Tyrosine metabolism";"Naphthalene degradation";"Butanol and isobutanol biosynthesis (engineered)";"Methane metabolism";"Pyruvate fermentation to isobutanol (engineered)";"alpha-Linolenic acid metabolism";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to ethanol III";"L-valine degradation II";"Glycolysis / Gluconeogenesis";"Metabolism of xenobiotics by cytochrome P450";"Fatty acid degradation";"Drug metabolism - cytochrome P450";"L-methionine degradation III";"Pyruvate fermentation to ethanol II";"Chitin degradation to ethanol";"Acetaldehyde biosynthesis I";"(S)-propane-1,2-diol degradation";"L-leucine degradation III";"L-phenylalanine degradation III";"3-methylbutanol biosynthesis (engineered)";"Salidroside biosynthesis";"Formaldehyde oxidation II (glutathione-dependent)";"Protein S-nitrosylation and denitrosylation";"Serotonin degradation";"L-isoleucine degradation II";"Ethanol oxidation";"Phenylethanol biosynthesis";"Noradrenaline and adrenaline degradation"
XP_046479860.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046478205.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_046474850.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_046481765.1	26	Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-389977	"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Prometaphase";"Cilium Assembly";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway"
XP_046468899.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763	"Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction"
XP_046484400.1	24	Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G alpha (i) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_046470339.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046484513.1	9	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046491114.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046470933.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135	"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation"
XP_046465502.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046483834.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_046477776.1	4	Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling"
XP_046466849.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046467790.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis"
XP_046484247.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046469325.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046466759.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_046488310.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046465168.1	4	KEGG: 00983+2.3.1.5;Reactome: R-HSA-156582;KEGG: 00633+2.3.1.5;KEGG: 00232+2.3.1.5	"Drug metabolism - other enzymes";"Acetylation";"Nitrotoluene degradation";"Caffeine metabolism"
XP_046476450.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046469620.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_046475593.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046468023.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046466398.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046468224.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_046485440.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046488075.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046467254.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046482869.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046489754.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046488395.1	5	KEGG: 00562+3.1.3.64;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64;Reactome: R-HSA-1660499;MetaCyc: PWY-6580	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_046488093.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211	"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling"
XP_046486749.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046486092.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition"
XP_046475626.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046491421.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046486447.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_046492632.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046488361.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046489668.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046476833.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046473390.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046484977.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046487563.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_046483740.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046466468.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046486494.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_046470377.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046468993.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046474129.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046493122.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046479117.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046482603.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046471613.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046465557.1	5	Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955	"RAF activation";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_046475780.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046467016.1	4	MetaCyc: PWY-2781;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75	"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Zeatin biosynthesis"
XP_046484305.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046469134.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046481488.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_046488728.1	7	KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-46;MetaCyc: PWY-4984;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;MetaCyc: PWY-6922	"Arginine and proline metabolism";"Canavanine degradation";"Putrescine biosynthesis III";"Urea cycle";"Urea cycle";"Arginine biosynthesis";"L-Ndelta-acetylornithine biosynthesis"
XP_046491282.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046480483.1	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_046483778.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046479650.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_046489908.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046477295.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046479219.1	7	Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046485083.1	11	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"p38MAPK events";"Human papillomavirus infection";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046471411.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_046482383.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046468600.1	11	Reactome: R-HSA-500753;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7791;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3	"Pyrimidine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism"
XP_046476117.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_046481351.1	10	Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23	"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"HS-GAG degradation";"Galactose metabolism";"Other glycan degradation"
XP_046483868.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046482210.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046468959.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046487468.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_046469363.1	10	KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861	"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_046479667.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_046466052.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_046483011.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046492175.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046492165.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046472659.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046491516.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046473244.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046476344.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046465620.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_046469852.1	7	KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897	"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes"
XP_046476787.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046479714.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046482404.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046483944.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046483147.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046466900.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046466195.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_046466579.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_046469064.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046479970.1	8	Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633	"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_046474991.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981	"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III"
XP_046476180.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046475539.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_046469087.1	16	Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585	"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence"
XP_046474370.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046470154.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046484543.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046481340.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046491767.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046491603.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046485097.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046484875.1	7	Reactome: R-HSA-446205;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456	"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation"
XP_046482558.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046481179.1	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification"
XP_046477625.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046475150.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046475031.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046477282.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_046491438.1	6	MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism"
XP_046492044.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676	"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_046469894.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_046472239.1	8	MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6;KEGG: 00710+5.3.1.6;Reactome: R-HSA-6791461;KEGG: 00030+5.3.1.6;Reactome: R-HSA-5659996	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P"
XP_046473220.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055	"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_046484889.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046477613.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046475037.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046468964.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046474618.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_046485819.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-389357;Reactome: R-HSA-114604;Reactome: R-HSA-416476;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-1433557	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"RET signaling";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"CD28 dependent PI3K/Akt signaling";"GPVI-mediated activation cascade";"G alpha (q) signalling events";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"Signaling by SCF-KIT"
XP_046487673.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_046490172.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046488046.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_046466850.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046476788.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046470472.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046466581.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_046473776.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis"
XP_046492182.1	3	KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_046477973.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046475886.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_046466990.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_046484062.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046465692.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046471962.1	17	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane"
XP_046488367.1	10	Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-1912408	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation"
XP_046465954.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_046478221.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046481753.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046470901.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110331	"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine"
XP_046480294.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046469060.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046473383.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046471479.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046478430.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046466692.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046484102.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_046484338.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7007	"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)"
XP_046482565.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046486145.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046486864.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046489521.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_046482538.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046487639.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046483309.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046486638.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_046478319.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046483954.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046482617.1	13	Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52	"Hyaluronan uptake and degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_046482689.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_046488196.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046482973.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046484486.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046485999.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046474919.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046487556.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046466447.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_046469019.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046479670.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_046487932.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046466462.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046488523.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046471334.1	31	Reactome: R-HSA-9029558;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWY-5994;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-5366;MetaCyc: PWY-5971;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-7663;Reactome: R-HSA-163765;MetaCyc: PWY-5142	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Gondoate biosynthesis (anaerobic)";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway"
XP_046472507.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046471243.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046484828.1	4	MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046467419.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695	"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events"
XP_046475632.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046469337.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046474198.1	7	KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226	"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI"
XP_046491518.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046483864.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_046476644.1	5	Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046492239.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046491174.1	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5632927	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH3"
XP_046487977.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_046480856.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7115	"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_046470100.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046476809.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_046478464.1	6	Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_046472966.1	3	Reactome: R-HSA-6799198;Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Complex I biogenesis";"Mitochondrial protein import";"Respiratory electron transport"
XP_046492822.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046471379.1	13	Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-5357956	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway"
XP_046490179.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_046484341.1	20	MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7858	"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II"
XP_046474507.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046483297.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_046479090.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_046485743.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046492198.1	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_046485048.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046474766.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046484886.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_046488432.1	8	Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism"
XP_046484448.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_046465381.1	4	KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221	"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046474767.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046480599.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_046487058.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-191859	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"snRNP Assembly"
XP_046481994.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046484876.1	4	MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_046487094.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046486089.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_046465518.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046483577.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046477608.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046484116.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046470674.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046470196.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_046482874.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046467958.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_046479053.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_046486298.1	13	KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"CS/DS degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series"
XP_046475943.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046483827.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_046489496.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046468343.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_046481955.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046491655.1	30	Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-2564830;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696395	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Cytosolic iron-sulfur cluster assembly";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER"
XP_046466193.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_046492730.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046482610.1	16	Reactome: R-HSA-166058;Reactome: R-HSA-1810476;Reactome: R-HSA-5602498;Reactome: R-HSA-975871;Reactome: R-HSA-975155;Reactome: R-HSA-209543;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-5602680;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-9020702;Reactome: R-HSA-975138;Reactome: R-HSA-1236974;Reactome: R-HSA-5603037;Reactome: R-HSA-3134963	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"p75NTR recruits signalling complexes";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR5)";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-1 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"ER-Phagosome pathway";"IRAK4 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"
XP_046490693.1	12	MetaCyc: PWY-5133;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5108;MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-6672	"Colupulone and cohumulone biosynthesis";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation"
XP_046472417.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"RORA activates gene expression";"PPARA activates gene expression"
XP_046470487.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046474803.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046475194.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046485448.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046486508.1	12	MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-6978	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II"
XP_046469794.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_046483133.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046478914.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_046468893.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046485338.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046487698.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046466368.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_046468340.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-168333	"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_046468302.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046477761.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516	"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation"
XP_046482786.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046466515.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_046487501.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_046469227.1	6	KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403	"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)"
XP_046469856.1	7	Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_046464710.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046491145.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046484717.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046466383.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_046477516.1	10	Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-400206	"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha"
XP_046492628.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy"
XP_046488872.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046479925.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_046481776.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046480329.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_046465951.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_046483041.1	13	MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-6383;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-5123	"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_046493106.1	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_046476912.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046474369.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_046466231.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-113501	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_046492603.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046492869.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046487638.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046470073.1	14	MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1	"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"One carbon pool by folate";"Methane metabolism";"Folate transformations I";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate transformations II (plants)";"Glycine, serine and threonine metabolism"
XP_046470003.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046467473.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046485815.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046486769.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046477056.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046489049.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046488263.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046481883.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046467997.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046490191.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046482251.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_046469257.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781	"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression"
XP_046482169.1	13	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-389357;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-1257604;Reactome: R-HSA-165159	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"CD28 dependent PI3K/Akt signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"PIP3 activates AKT signaling";"mTOR signalling"
XP_046464932.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_046478868.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_046484910.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046466608.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630	"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3"
XP_046485341.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046485708.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_046492259.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046483086.1	8	Reactome: R-HSA-5683826;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4	"Surfactant metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Purine metabolism"
XP_046475414.1	4	KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines"
XP_046482443.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046477948.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_046480068.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046479471.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_046477651.1	26	Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276	"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly";"Cilium Assembly";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_046487254.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046481545.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046468112.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_046489202.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046489676.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046465587.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046485612.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_046480021.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827	"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex"
XP_046478381.1	18	KEGG: 00400+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Sulfolactate degradation III";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation"
XP_046487436.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_046477316.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046487740.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_046489308.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046482093.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046466504.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046471879.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046475190.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046477141.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046491634.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046481770.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046473032.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_046475256.1	4	Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_046465594.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_046479974.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_046465372.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046473180.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046471790.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046484262.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046487853.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046476910.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046488603.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046489803.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs"
XP_046469385.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids"
XP_046471335.1	31	MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-6799;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-5147;MetaCyc: PWY-8012;MetaCyc: PWYG-321;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-9029558;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-7746	"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis"
XP_046468886.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046488726.1	1	Reactome: R-HSA-156581	"Methylation"
XP_046470765.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046475761.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_046480098.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046480361.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046473226.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046478624.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046484510.1	9	Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046486528.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046481743.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046491140.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046477947.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046464865.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046483536.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046464909.1	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_046487126.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046467546.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046473373.1	7	KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-7790	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I";"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis II"
XP_046492086.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046471878.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046471614.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046468454.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex"
XP_046479181.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046479001.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046464775.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046465595.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_046487822.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046476082.1	20	Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210	"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046473672.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046482125.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046486443.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046485704.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade"
XP_046481507.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_046475594.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046473331.1	6	KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism"
XP_046487508.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_046481425.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046479169.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_046492497.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046474368.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046489557.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_046484109.1	57	Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
XP_046485174.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046479248.1	14	Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_046479131.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046477326.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046464721.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046491847.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046469754.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046475558.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_046464722.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046479797.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046476986.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046478226.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046473102.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046486877.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046465697.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046477975.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7724	"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046483332.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046476936.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_046485618.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046485633.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046478802.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046464835.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046471339.1	31	MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-7723;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5366;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381	"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"Pederin biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_046466903.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046474555.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046484007.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_046466820.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046467204.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_046488259.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046479094.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046485086.1	11	KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"p38MAPK events";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046474479.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046477548.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046472934.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046484198.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046476508.1	19	Reactome: R-HSA-5625970;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-428543;Reactome: R-HSA-8950505	"RHO GTPases activate KTN1";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"EGFR downregulation";"GPVI-mediated activation cascade";"Rho GTPase cycle";"Myogenesis";"MAPK6/MAPK4 signaling";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_046465421.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_046475833.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046479011.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046467248.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046465404.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046480735.1	18	Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167200	"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_046491826.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046468773.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046490408.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046485561.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046492659.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046476636.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046491665.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_046476134.1	17	Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-196780	"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Biotin transport and metabolism"
XP_046467653.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046483507.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_046483439.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046476506.1	19	Reactome: R-HSA-428543;Reactome: R-HSA-8950505;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-5663220	"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"Myogenesis";"MAPK6/MAPK4 signaling";"G beta:gamma signalling through CDC42";"EGFR downregulation";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"RHO GTPases Activate Formins"
XP_046487980.1	27	Reactome: R-HSA-5467348;Reactome: R-HSA-399956;KEGG: 04714+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-3371453;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5610785;Reactome: R-HSA-5250924;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262	"Truncations of AMER1 destabilize the destruction complex";"CRMPs in Sema3A signaling";"Thermogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Regulation of HSF1-mediated heat shock response";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Human papillomavirus infection";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"GLI3 is processed to GLI3R by the proteasome";"B-WICH complex positively regulates rRNA expression";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"mTOR signaling pathway";"Relaxin signaling pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_046482292.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_046474013.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_046471517.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046485258.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046470572.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046465092.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_046465721.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046483796.1	26	Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-5663220	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Cilium Assembly";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins"
XP_046483795.1	17	Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-174417	"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis"
XP_046470902.1	7	Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110330	"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_046490307.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046474159.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046486226.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046485614.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046468053.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046471777.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046470281.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046487096.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046481923.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046491194.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046485529.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046488136.1	6	MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;Reactome: R-HSA-196807	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism"
XP_046480211.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046466497.1	17	Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-4086398;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-937072	"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Ca2+ pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046481194.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046486112.1	5	Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-166208	"mTOR signalling";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"mTORC1-mediated signalling"
XP_046486556.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459	"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046472889.1	14	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Retinoid metabolism and transport";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_046488285.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046479259.1	18	MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417	"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_046486444.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046467655.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046491560.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046492262.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046469746.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_046479101.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046467964.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_046481972.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046488072.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_046469158.1	11	Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642	"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling"
XP_046477891.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046485068.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046468887.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046493099.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046469086.1	16	Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897	"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes"
XP_046484550.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_046468633.1	7	Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_046491138.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_046487172.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-4641257	"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN"
XP_046466584.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046466606.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399	"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_046489395.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046464717.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046471345.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_046478901.1	7	KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2	"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_046471177.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046492668.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046472338.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046492835.1	4	MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046466769.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046467631.1	17	Reactome: R-HSA-1912408;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-2559580;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-139915;Reactome: R-HSA-6804114;Reactome: R-HSA-113501;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-9616222;Reactome: R-HSA-1538133;Reactome: R-HSA-8953750;Reactome: R-HSA-69205;Reactome: R-HSA-111448	"Pre-NOTCH Transcription and Translation";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Oxidative Stress Induced Senescence";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of granulopoiesis";"G0 and Early G1";"Transcriptional Regulation by E2F6";"G1/S-Specific Transcription";"Activation of NOXA and translocation to mitochondria"
XP_046482821.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-9615710;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8856825;Reactome: R-HSA-9646399	"RHO GTPases regulate CFTR trafficking";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"Late endosomal microautophagy";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Cargo recognition for clathrin-mediated endocytosis";"Aggrephagy"
XP_046489807.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046488835.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046466520.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046473953.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046469024.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046467207.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046467416.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046482825.1	9	Reactome: R-HSA-8856825;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-5627083;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-9615710	"Cargo recognition for clathrin-mediated endocytosis";"Aggrephagy";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"RHO GTPases regulate CFTR trafficking";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Late endosomal microautophagy"
XP_046473130.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_046477293.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046490332.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_046475481.1	4	Reactome: R-HSA-5674400;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-198693	"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus"
XP_046490308.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_046484087.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046489519.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_046492582.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_046470658.1	13	KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;Reactome: R-HSA-74259;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7184;MetaCyc: PWY-7821	"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine catabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis"
XP_046476808.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_046489254.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_046472334.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046485493.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046489965.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_046490331.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_046474952.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046470057.1	8	Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation"
XP_046488831.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046482196.1	20	Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756	"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation"
XP_046476034.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_046482993.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046478780.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_046482702.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_046478782.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046472187.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_046474175.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046479844.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046472605.1	13	KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7226	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_046476302.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046488412.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046474365.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046486373.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046490373.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046489855.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046465182.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046468042.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046468905.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046483259.1	8	Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"ATP biosynthesis";"Oxidative phosphorylation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Photosynthesis";"Ion channel transport";"Amino acids regulate mTORC1"
XP_046479173.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046470830.1	7	MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Adenine and adenosine salvage II";"Purine metabolism";"Adenine salvage";"Purine salvage";"Neutrophil degranulation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_046464833.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_046489677.1	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
XP_046467383.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_046480862.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046470079.1	16	Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-164939;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-3928665	"Recycling pathway of L1";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"LDL clearance";"WNT5A-dependent internalization of FZD4";"Nef mediated downregulation of CD28 cell surface expression";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells"
XP_046489479.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046485705.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046483242.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046473218.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51	"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism"
XP_046484202.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046466806.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046465624.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_046482418.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046476091.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046466687.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046473934.1	22	KEGG: 00010+5.3.1.9;Reactome: R-HSA-70263;MetaCyc: PWY-5514;MetaCyc: PWY-6992;MetaCyc: PWY-6142;MetaCyc: PWY-5659;Reactome: R-HSA-5628897;MetaCyc: PWY-3801;MetaCyc: PWY-7385;MetaCyc: PWY-622;MetaCyc: PWY-7347;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-6981;MetaCyc: PWY-621;Reactome: R-HSA-70171;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5384;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5054;MetaCyc: PWY-8013;KEGG: 00500+5.3.1.9	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"1,5-anhydrofructose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"GDP-mannose biosynthesis";"TP53 Regulates Metabolic Genes";"Sucrose degradation II (sucrose synthase)";"1,3-propanediol biosynthesis (engineered)";"Starch biosynthesis";"Sucrose biosynthesis III";"Sucrose biosynthesis II";"Neutrophil degranulation";"Chitin biosynthesis";"Sucrose degradation III (sucrose invertase)";"Glycolysis";"Pentose phosphate pathway";"Sucrose degradation IV (sucrose phosphorylase)";"Amino sugar and nucleotide sugar metabolism";"D-sorbitol biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Starch and sucrose metabolism"
XP_046484639.1	14	MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1	"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes"
XP_046479416.1	11	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046474864.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046478872.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_046469606.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_046482215.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046489700.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
XP_046485741.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046484336.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-735	"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis"
XP_046474800.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046481741.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046479623.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046483950.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_046468645.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046485702.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046486229.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046475203.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046480051.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046482046.1	11	Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-9018519	"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression"
XP_046483783.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046476033.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_046483629.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046486489.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046468424.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046483666.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046489840.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046472348.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046487654.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046474989.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-241	"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_046482543.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046482837.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_046467209.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046489751.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_046470966.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046477320.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046488393.1	6	KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660517	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane"
XP_046476499.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046489035.1	4	MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7394;MetaCyc: PWY-7849	"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin III"
XP_046492032.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5610780	"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome"
XP_046471753.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046468002.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046478691.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_046484611.1	4	KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268	"Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_046489299.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_046466524.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_046489151.1	8	KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism"
XP_046492209.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046473372.1	7	MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10	"UMP biosynthesis III";"Drug metabolism - other enzymes";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Pyrimidine metabolism"
XP_046491906.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_046490194.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046475453.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"RAF activation";"Ion transport by P-type ATPases";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_046475033.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046466110.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046493142.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046475036.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046470072.1	14	MetaCyc: PWY-5497;MetaCyc: PWY-3661;Reactome: R-HSA-196757;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-1622;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161	"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation I";"Metabolism of folate and pterines";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"Cyanoamino acid metabolism";"Folate transformations I";"One carbon pool by folate";"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation"
XP_046485412.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046489370.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046471980.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
XP_046486916.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046482457.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_046473229.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046490730.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046473595.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046486530.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046490594.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_046491777.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046486124.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046473338.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism"
XP_046473855.1	8	Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483	"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs"
XP_046493371.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis"
XP_046478932.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_046489477.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046470207.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046489206.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046480433.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046481825.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046481822.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046468335.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_046478817.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_046480438.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695	"HIV Transcription Initiation";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events"
XP_046485104.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046492457.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046478263.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046481617.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046483633.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046489057.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046488048.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_046484687.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046488568.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046470991.1	4	KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis"
XP_046470815.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-674695	"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events"
XP_046492693.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046474876.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046470127.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046467654.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_046474838.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_046489821.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_046482035.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046467674.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837	"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation"
XP_046483842.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6	"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism"
XP_046488045.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_046466292.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046475875.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046466175.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046466130.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046480942.1	8	Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695	"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation"
XP_046482410.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046477089.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046487652.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046477970.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166	"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2"
XP_046493355.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_046477188.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046476886.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046489211.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825	"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis"
XP_046490630.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_046470928.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046471842.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046470971.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046488430.1	8	KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;MetaCyc: PWY-7193;MetaCyc: PWY-6556;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_046475027.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046475944.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046488325.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_046480406.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_046465403.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046467156.1	5	KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_046479695.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046466213.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176412	"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C"
XP_046464878.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398	"cGMP effects";"Rap1 signalling";"Ca2+ pathway"
XP_046469156.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196	"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling"
XP_046482677.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046473814.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619	"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN"
XP_046479494.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168325	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis"
XP_046472732.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357	"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling"
XP_046474504.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046466489.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046470879.1	5	Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225	"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_046488839.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046475817.1	40	Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-6781827	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_046491644.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046468884.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046474155.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_046469290.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046483850.1	20	MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7337	"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_046482277.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046474306.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046483130.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_046468092.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_046489581.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046489142.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046467953.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046490102.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_046492036.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046468345.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_046468063.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046486692.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046468404.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_046481455.1	6	MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-6608;MetaCyc: PWY-5497;Reactome: R-HSA-74259	"Guanosine nucleotides degradation II";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism"
XP_046482850.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_046473869.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046482008.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_046467934.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046488816.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046472383.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046491604.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046470764.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046472389.1	5	Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism"
XP_046470909.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046470446.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046492750.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046483878.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046481622.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_046486479.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_046487327.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_046479655.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046468173.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046488433.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_046492324.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_046479105.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046476155.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_046481841.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_046480852.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-6142	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_046485387.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_046467228.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046473496.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_046472938.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509	"RMTs methylate histone arginines";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes"
XP_046484619.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import"
XP_046471469.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046476642.1	5	Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4	"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism"
XP_046467957.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_046489596.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_046476911.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046483977.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046472730.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-389357	"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling"
XP_046465215.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046474338.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046469757.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046472932.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Interleukin-7 signaling"
XP_046482045.1	11	Reactome: R-HSA-3214858;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340	"RMTs methylate histone arginines";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation"
XP_046465188.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046470174.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_046481663.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046484026.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_046469259.1	9	Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781	"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression"
XP_046488565.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_046489219.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_046485564.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046491988.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046467246.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046465236.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046472241.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046485916.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046469068.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046492235.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_046465433.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046469764.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046488151.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_046470435.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046487328.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601	"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046481514.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040	"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_046474372.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046474196.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_046467669.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_046482945.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046482103.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046465850.1	8	Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-8949664;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Processing of SMDT1";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_046481192.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046489047.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046473723.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167152	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_046479306.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_046468810.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046468293.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168276	"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Early Events";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways"
XP_046482243.1	18	Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;MetaCyc: PWY-7511;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579	"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Protein ubiquitination";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange"
XP_046486529.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046472352.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_046480360.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046475512.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046478356.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046489960.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_046491656.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046465142.1	5	MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41	"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_046479865.1	11	Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-674695	"HIV Transcription Initiation";"HATs acetylate histones";"Ub-specific processing proteases";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events"
XP_046490766.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046473861.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Macroautophagy";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046469293.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046490683.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046465105.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_046481655.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046482435.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046493083.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_046471160.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_046470910.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046483903.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046465362.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046474945.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046480020.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867	"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex"
XP_046473779.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046474278.1	5	Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32	"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis"
XP_046483032.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046470722.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_046476291.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046483820.1	34	Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9639288;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-191859	"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Amino acids regulate mTORC1";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Separation of Sister Chromatids";"snRNP Assembly"
XP_046478801.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_046488619.1	6	Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16	"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046483432.1	10	KEGG: 05170+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5357956;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Regulation of TNFR1 signaling";"T cell receptor signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046483505.1	5	MetaCyc: PWY-7536;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism"
XP_046488996.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_046482977.1	6	MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3	"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophospholipid metabolism"
XP_046484023.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046479685.1	4	Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Signaling by BRAF and RAF fusions";"Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046481954.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046478272.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046467021.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046489012.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046474711.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046493395.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046490101.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism"
XP_046464788.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046469782.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_046482489.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046492661.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046464861.1	58	Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5689901;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-174084	"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Metalloprotease DUBs";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_046474474.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046465652.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046467576.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_046491753.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046488192.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046486285.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046476627.1	10	Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-200425;Reactome: R-HSA-5628897	"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carnitine metabolism";"TP53 Regulates Metabolic Genes"
XP_046484199.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046479675.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046477471.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046471003.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046467765.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-8943724;Reactome: R-HSA-450341;Reactome: R-HSA-8862803;Reactome: R-HSA-5687128;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-6796648	"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN gene transcription";"Activation of the AP-1 family of transcription factors";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"MAPK6/MAPK4 signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046478834.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity"
XP_046490037.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046475781.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046488150.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
XP_046468338.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_046472365.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046472718.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046486421.1	4	Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-1268020	"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import"
XP_046471676.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046469589.1	7	KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis"
XP_046482573.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_046483250.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_046488138.1	6	Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-7761	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)"
XP_046474470.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046492035.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046481995.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046490312.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046465538.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046481013.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046471341.1	31	Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-163765	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression"
XP_046487982.1	27	Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;KEGG: 05165+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-3371453;Reactome: R-HSA-5358747;Reactome: R-HSA-399956;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5467348;KEGG: 04151+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-5674400;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4641262;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5610785;Reactome: R-HSA-5250924	"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Regulation of HSF1-mediated heat shock response";"S33 mutants of beta-catenin aren't phosphorylated";"CRMPs in Sema3A signaling";"Thermogenesis";"Truncations of AMER1 destabilize the destruction complex";"PI3K-Akt signaling pathway";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by AKT1 E17K in Cancer";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"mTOR signaling pathway";"Relaxin signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"GLI3 is processed to GLI3R by the proteasome";"B-WICH complex positively regulates rRNA expression"
XP_046490196.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046488251.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046466451.1	3	KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3	"Purine metabolism";"Urate conversion to allantoin I";"Caffeine metabolism"
XP_046485016.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046468757.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046476215.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046484775.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046486653.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_046476831.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046479873.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046478729.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046479851.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046490924.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046478279.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Viral mRNA Translation"
XP_046470020.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046478045.1	12	Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-2122948	"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_046471569.1	11	MetaCyc: PWY-6596;MetaCyc: PWY-6999;Reactome: R-HSA-74259;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6608;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-6606;MetaCyc: PWY-6538;MetaCyc: PWY-5695;MetaCyc: PWY-5497	"Adenosine nucleotides degradation I";"Theophylline degradation";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Purine nucleobases degradation II (anaerobic)"
XP_046478870.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_046489909.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046466652.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_046485329.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046474034.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046468463.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096	"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation"
XP_046484225.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_046476586.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046483159.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046486040.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046492581.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046476307.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_046472945.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-982772	"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling"
XP_046492579.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_046465769.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046492494.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046470656.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046466894.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_046475041.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046491437.1	6	Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_046468225.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719	"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation"
XP_046471674.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046474498.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046469133.1	11	MetaCyc: PWY-7102;Reactome: R-HSA-191273;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7560;MetaCyc: PWY-7524;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6174	"Bisabolene biosynthesis (engineered)";"Cholesterol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)"
XP_046489731.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046490620.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046471993.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_046491562.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046472898.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046468181.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046469179.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_046491640.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046475289.1	2	Reactome: R-HSA-5687128;KEGG: 04150+2.7.11.24	"MAPK6/MAPK4 signaling";"mTOR signaling pathway"
XP_046473222.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055	"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_046489582.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046487318.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046488700.1	13	MetaCyc: PWY-7254;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-71403	"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)"
XP_046465931.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046491957.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046465662.1	3	Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078	"Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_046482402.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046488077.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046481060.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046469498.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046475506.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046475514.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046489152.1	8	Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1	"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_046481508.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling"
XP_046470756.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-202433;Reactome: R-HSA-2871796;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-2424491;KEGG: 00562+3.1.4.11	"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"FCERI mediated MAPK activation";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling";"Inositol phosphate metabolism"
XP_046472037.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_046469390.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046475640.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046486442.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046493102.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046483295.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_046485331.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046474197.1	7	KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_046480743.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046469119.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046471964.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046470825.1	7	MetaCyc: PWY-7805;Reactome: R-HSA-6798695;MetaCyc: PWY-7807;MetaCyc: PWY-6610;Reactome: R-HSA-74217;MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7	"(aminomethyl)phosphonate degradation";"Neutrophil degranulation";"Glyphosate degradation III";"Adenine salvage";"Purine salvage";"Adenine and adenosine salvage II";"Purine metabolism"
XP_046477751.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046466728.1	6	Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane"
XP_046481868.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046485140.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046490864.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046486545.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-9614657;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575	"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"FOXO-mediated transcription of cell death genes";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"Circadian Clock";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling"
XP_046472962.1	7	MetaCyc: PWY-6363;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_046475288.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046474906.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046489502.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046487107.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046483190.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046482679.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046484103.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_046479842.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046479359.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046491368.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046476973.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046480281.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046492663.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy"
XP_046491362.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_046467779.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046488957.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_046471572.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046470501.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046484616.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043	"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events"
XP_046479861.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046490239.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046492829.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046484643.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046469767.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046486101.1	9	MetaCyc: PWY-6142;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism"
XP_046488946.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046482875.1	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_046491904.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_046491121.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation"
XP_046469673.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046483136.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046476278.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046469748.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046482100.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046485788.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046490480.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046493201.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_046465082.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_046468516.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046487697.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046472232.1	8	Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-438066	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_046486031.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046476394.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046490182.1	52	Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-1834949;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-167200	"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_046473002.1	5	KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305	"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Keratan sulfate degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D"
XP_046478716.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046473345.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046471473.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046481178.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001	"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_046487661.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046491093.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046485221.1	18	KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-7416	"Ether lipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_046482889.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046484296.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046466477.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046491762.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_046488591.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046489592.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046490334.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_046465382.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046468414.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-9603505;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-113418	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"NTRK3 as a dependence receptor";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex"
XP_046483037.1	13	MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-7736;MetaCyc: PWY-7721;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7102	"Ipsdienol biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Methyl phomopsenoate biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)"
XP_046484903.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046487050.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046473963.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046470149.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046467817.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046485154.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_046477986.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036	"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
XP_046482824.1	9	Reactome: R-HSA-9646399;Reactome: R-HSA-8856825;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-9615710;Reactome: R-HSA-5689880;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-5627083	"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Late endosomal microautophagy";"Ub-specific processing proteases";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"RHO GTPases regulate CFTR trafficking"
XP_046475373.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_046489213.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis"
XP_046480315.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046473858.1	8	Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_046483331.1	5	Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407	"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_046481752.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046480003.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046478459.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046484008.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_046482618.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046473569.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_046471331.1	4	Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8	"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_046489466.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046482595.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046473116.1	4	MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_046466369.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_046470109.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046490629.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_046489398.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159231	"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046479548.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_046472363.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046476038.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046482820.1	9	Reactome: R-HSA-9646399;Reactome: R-HSA-8856825;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-9615710;Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-9613829;Reactome: R-HSA-5627083	"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Late endosomal microautophagy";"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"RHO GTPases regulate CFTR trafficking"
XP_046479633.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046477489.1	33	Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-69656;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"Cyclin A:Cdk2-associated events at S phase entry";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape"
XP_046470264.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046476720.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046470767.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046489627.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046471456.1	13	Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-450321	"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046474481.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859	"Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046484454.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_046475298.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046483838.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046471278.1	14	Reactome: R-HSA-1632852;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-9648025	"Macroautophagy";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Intraflagellar transport";"EML4 and NUDC in mitotic spindle formation"
XP_046486815.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_046488288.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046493349.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_046479652.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_046486449.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_046477575.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_046475483.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000	"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Long-term potentiation";"RAF/MAP kinase cascade";"RAF activation"
XP_046477508.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-427413	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression"
XP_046483211.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046492667.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046471035.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046484088.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_046484226.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_046480230.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046471862.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046469824.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046486059.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046478789.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046484455.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046475623.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046485171.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046467245.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046489675.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_046466815.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046468872.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_046472184.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046480855.1	9	MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism"
XP_046488090.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046465559.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_046477754.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046488267.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046487245.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046477310.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046470985.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
XP_046493032.1	9	Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-1042	"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)"
XP_046492250.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_046490944.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046479642.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046469226.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046487043.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046467051.1	8	MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086	"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_046477278.1	12	MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_046465038.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_046479196.1	8	Reactome: R-HSA-1483148;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5668;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 00564+3.1.3.27	"Synthesis of PG";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Glycerophospholipid metabolism"
XP_046464734.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Ethylene biosynthesis III (microbes)"
XP_046474810.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046466594.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046476894.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
XP_046477304.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046474055.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68962	"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex"
XP_046475029.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046482976.1	6	MetaCyc: PWY-6952;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560	"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism"
XP_046482762.1	3	Reactome: R-HSA-196741;Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism"
XP_046476714.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046467139.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046489938.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046469115.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046492362.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046481239.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_046492981.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046465225.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046491602.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046470463.1	14	MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-7279;Reactome: R-HSA-71403;MetaCyc: PWY-4302;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1	"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Butanoate metabolism"
XP_046475791.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_046470134.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046473537.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046492789.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046489270.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046492181.1	4	MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_046464830.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
XP_046491931.1	30	MetaCyc: PWY-6871;MetaCyc: PWY-5079;MetaCyc: PWY-6802;MetaCyc: PWY-5076;MetaCyc: PWY-7013;MetaCyc: PWY-6342;MetaCyc: PWY-5751;MetaCyc: PWY-6587;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-6313;MetaCyc: PWY-3162;MetaCyc: PWY-5078;MetaCyc: PWY-5480;MetaCyc: PWY-5082;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00625+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00982+1.1.1.1;KEGG: 00010+1.1.1.1;KEGG: 00071+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5057;Reactome: R-HSA-211981;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7396;MetaCyc: PWY-6333;KEGG: 00350+1.1.1.1	"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Salidroside biosynthesis";"L-leucine degradation III";"(S)-propane-1,2-diol degradation";"Noradrenaline and adrenaline degradation";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol III";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to isobutanol (engineered)";"Serotonin degradation";"L-tryptophan degradation V (side chain pathway)";"L-isoleucine degradation II";"Pyruvate fermentation to ethanol I";"L-methionine degradation III";"Retinol metabolism";"Pyruvate fermentation to ethanol II";"Chloroalkane and chloroalkene degradation";"Glycine, serine and threonine metabolism";"Drug metabolism - cytochrome P450";"Glycolysis / Gluconeogenesis";"Fatty acid degradation";"Metabolism of xenobiotics by cytochrome P450";"L-valine degradation II";"Xenobiotics";"Naphthalene degradation";"Chitin degradation to ethanol";"Butanol and isobutanol biosynthesis (engineered)";"Acetaldehyde biosynthesis I";"Tyrosine metabolism"
XP_046488100.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_046471154.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_046487859.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046470245.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046492564.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_046475675.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_046465519.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046482234.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691	"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling"
XP_046473368.1	7	KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis II";"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis I"
XP_046484001.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046471873.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046472340.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046466858.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_046489113.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046481620.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046492229.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_046470441.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046481629.1	33	Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-165054	"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA"
XP_046465069.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046466937.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046474547.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046466125.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046480626.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_046470908.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046492540.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046482200.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046487299.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046480522.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046467703.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046483244.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046477346.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046477780.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046488678.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046485071.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046483503.1	5	KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7536;MetaCyc: PWY-5189	"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046472096.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046476577.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046481008.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046486271.1	13	MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)"
XP_046467255.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046466566.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046475207.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046483142.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046487207.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046478227.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046480405.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_046486008.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046475583.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046480510.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695	"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation"
XP_046476324.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046477648.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_046486034.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046471313.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_046479150.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046481452.1	6	Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6608	"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III"
XP_046475320.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046477462.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046465745.1	7	MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-6124	"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II"
XP_046475217.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046478788.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046486063.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046473812.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941	"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses"
XP_046491021.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046483173.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_046487532.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_046489261.1	6	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-8876198;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Late endosomal microautophagy";"HCMV Late Events";"RAB GEFs exchange GTP for GDP on RABs";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046471778.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046479620.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046483957.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-936440	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling"
XP_046482173.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046484484.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046465330.1	5	Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852	"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Macroautophagy"
XP_046491582.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046480372.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046486777.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046477760.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation"
XP_046483533.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046489815.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046490690.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046486044.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046490569.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046476050.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046479645.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046467110.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_046479174.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046484236.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046471222.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046484869.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_046464968.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_046468274.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_046487605.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046474918.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_046482884.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046490124.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046474170.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046480574.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046475750.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046484337.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7858	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II"
XP_046474937.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046476294.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046480682.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046481749.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046473344.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046480255.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046485685.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046483241.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046487854.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046472892.1	14	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism"
XP_046489827.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046484792.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046489396.1	10	Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-5628897	"Regulation of the apoptosome activity";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes"
XP_046487642.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046487709.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046488434.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_046483040.1	13	MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659	"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis"
XP_046477280.1	12	MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism"
XP_046482098.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046476264.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_046491577.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046487472.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046466500.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046468276.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-6785807;Reactome: R-HSA-452723;Reactome: R-HSA-2892247;Reactome: R-HSA-2892245;Reactome: R-HSA-8986944	"Deactivation of the beta-catenin transactivating complex";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation of pluripotent stem cells";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Transcriptional Regulation by MECP2"
XP_046468541.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046480151.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046466370.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_046470557.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046469801.1	5	Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-75109	"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation";"Triglyceride biosynthesis"
XP_046477336.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046480675.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046468906.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046476243.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046465273.1	3	KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_046471925.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870	"Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_046468752.1	8	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046480479.1	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation"
XP_046468247.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046475473.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892	"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation"
XP_046477106.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_046486909.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046477905.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046493037.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046473100.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046487564.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046485038.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046488257.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046464875.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046486111.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-198323	"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"mTOR signalling";"AKT phosphorylates targets in the cytosol"
XP_046470976.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046487695.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_046490851.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046467200.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_046468000.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046480256.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046480127.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046493180.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046473561.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046478413.1	20	Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Termination of translesion DNA synthesis"
XP_046477311.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046479798.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046483428.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_046489201.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046487656.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046475829.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649	"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation"
XP_046489838.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046466304.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-437239	"Cilium Assembly";"Gap junction assembly";"Mitotic Prometaphase";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1"
XP_046469967.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046465768.1	7	MetaCyc: PWY-7295;MetaCyc: PWY-7854;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-6969;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7118	"L-arabinose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Pyruvate metabolism";"D-xylose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol"
XP_046466586.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046490681.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046472367.1	7	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins"
XP_046479374.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046465520.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046471071.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046469407.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046486478.1	4	MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_046471342.1	31	MetaCyc: PWY-7663;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-5366;MetaCyc: PWY-5971;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-7723;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-8012;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14	"Gondoate biosynthesis (anaerobic)";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"Pederin biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis"
XP_046467413.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046488306.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046475449.1	7	Reactome: R-HSA-9033241;KEGG: 00280+4.1.3.4;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4	"Peroxisomal protein import";"Valine, leucine and isoleucine degradation";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Geraniol degradation"
XP_046466869.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046482259.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046472364.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046469029.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046486767.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046481305.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046470205.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046467807.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046471218.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046491587.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046473117.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046471111.1	31	MetaCyc: PWY-6799;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-7858;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-8047;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-7746	"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis"
XP_046478524.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046466196.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_046470376.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046465422.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_046470607.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046488909.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046482444.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046475560.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_046480061.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046485503.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046490388.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046466424.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046484254.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046477611.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046480242.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_046472665.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046473242.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046487752.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046476062.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Choline catabolism";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046467922.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046474054.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress"
XP_046478913.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_046468337.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_046472134.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046477129.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046469999.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046489007.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046476415.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046487186.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046469273.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-5469	"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Betanidin degradation";"Sesamin biosynthesis"
XP_046474373.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046475916.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_046479106.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046491706.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_046481547.1	13	MetaCyc: PWY-7226;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-6545	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_046474195.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_046492526.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046469188.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046466510.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046492154.1	11	Reactome: R-HSA-9627069;Reactome: R-HSA-1268020;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-5628897	"Regulation of the apoptosome activity";"Mitochondrial protein import";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes"
XP_046466727.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66	"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism"
XP_046484848.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_046485549.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_046491086.1	6	Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-975634	"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events";"Amyloid fiber formation";"Neutrophil degranulation";"Retinoid metabolism and transport"
XP_046475721.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316	"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_046486614.1	10	KEGG: 00240+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-3841;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-69205;MetaCyc: PWY-7199;MetaCyc: PWY-7187;MetaCyc: PWY-7198	"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Folate transformations II (plants)";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_046469780.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046480792.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046479004.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046481193.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_046490921.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046473722.1	12	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
XP_046470448.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046486032.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046483737.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046481011.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046478267.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046477458.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046474840.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046466549.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046486581.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046491605.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046475250.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_046468219.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046479720.1	5	KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95;Reactome: R-HSA-977347;KEGG: 00680+1.1.1.95;MetaCyc: PWY-8010	"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
XP_046471924.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6794361;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins";"Neutrophil degranulation"
XP_046469277.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046473539.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046487972.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046465672.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046483945.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_046480693.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_046470668.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046471439.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046483482.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046491642.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046491630.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046465475.1	14	MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-6453;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4	"Anandamide biosynthesis I";"Sphingolipid metabolism";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Synthesis of PC";"Anandamide biosynthesis II";"Ether lipid metabolism"
XP_046476468.1	3	Reactome: R-HSA-5666185;KEGG: 00900+2.7.7.60;MetaCyc: PWY-7560	"RHO GTPases Activate Rhotekin and Rhophilins";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
XP_046478475.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046483059.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046487807.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046474643.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046469017.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046485528.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046469529.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046469282.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046467706.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046476323.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046470151.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046471756.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_046467791.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_046476042.1	4	MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_046468540.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046465621.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046489839.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046492754.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046467632.1	17	Reactome: R-HSA-113501;Reactome: R-HSA-2559585;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-9616222;Reactome: R-HSA-1538133;Reactome: R-HSA-111448;Reactome: R-HSA-69205;Reactome: R-HSA-1912408;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69231;Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-2559580;Reactome: R-HSA-6804114	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oncogene Induced Senescence";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of granulopoiesis";"G0 and Early G1";"Activation of NOXA and translocation to mitochondria";"G1/S-Specific Transcription";"Pre-NOTCH Transcription and Translation";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin D associated events in G1";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Oxidative Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_046480741.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046489670.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046477469.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_046487289.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046467329.1	9	Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-9630222;Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-9608287;Reactome: R-HSA-9608290;Reactome: R-HSA-110329;Reactome: R-HSA-9630221	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective NTHL1 substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Defective MUTYH substrate binding";"Defective MUTYH substrate processing";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing"
XP_046489896.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046479098.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046488735.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046466906.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"MAP2K and MAPK activation";"mTOR signalling";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_046484273.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829	"SUMOylation of transcription cofactors";"Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy"
XP_046485808.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046487201.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046473105.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046480509.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)"
XP_046473628.1	19	KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-6545;Reactome: R-HSA-380270;Reactome: R-HSA-380320;MetaCyc: PWY-7227	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_046492757.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_046482471.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046483901.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046479759.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-5250924	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"B-WICH complex positively regulates rRNA expression"
XP_046478435.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046465175.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046484326.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046483839.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046464948.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046480216.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046472832.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046471203.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046484299.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046487888.1	10	Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761	"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_046465953.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_046480835.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046474608.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046471022.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046471675.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046484015.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046492770.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_046482297.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046466286.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_046489603.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_046466152.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046471729.1	7	Reactome: R-HSA-1474151;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate biosynthesis";"G1/S-Specific Transcription";"One carbon pool by folate";"Tetrahydrofolate biosynthesis"
XP_046469968.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046466694.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_046472888.1	14	KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409	"Ether lipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_046466783.1	12	Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"NRAGE signals death through JNK"
XP_046469289.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046489115.1	26	Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-6811436	"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Cilium Assembly";"Mitotic Prometaphase";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046486454.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_046482201.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046476198.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046469515.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046491515.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046473286.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046488222.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046468953.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_046487464.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046487471.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046481642.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046478515.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046492183.1	3	KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_046478566.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466	"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis"
XP_046473517.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_046471999.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046467902.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046486766.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046491358.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_046476121.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046474944.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046482013.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046488931.1	6	Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13	"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_046483541.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_046474037.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046492059.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_046487458.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046488715.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51	"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
XP_046484498.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046487567.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_046470206.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046480326.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785	"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Neddylation";"GLI3 is processed to GLI3R by the proteasome"
XP_046475704.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046473775.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046473888.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
XP_046491687.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_046472790.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046479095.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046475445.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_046479624.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046470877.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2"
XP_046486618.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046477366.1	8	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling by Hippo";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046487763.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046480857.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-5744	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation"
XP_046485714.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade"
XP_046474719.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046484235.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046467129.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling by Hippo";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_046484843.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_046467025.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046465045.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046487820.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046470119.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046481083.1	18	MetaCyc: PWY-5913;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7117	"Partial TCA cycle (obligate autotrophs)";"Tyrosine metabolism";"Sulfolactate degradation III";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Arginine biosynthesis";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_046467939.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046471863.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046469753.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046480801.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046482376.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046475356.1	5	MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_046469020.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046478024.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_046482537.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046485250.1	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632	"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_046481145.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046487502.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046467130.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046491203.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046473540.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046470157.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046476693.1	3	KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963;Reactome: R-HSA-947581	"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046473185.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046473215.1	14	Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417	"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)"
XP_046485610.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046481118.1	12	Reactome: R-HSA-194840;Reactome: R-HSA-5655302;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648	"Rho GTPase cycle";"Signaling by FGFR1 in disease";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK"
XP_046478307.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_046483849.1	20	MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-5136	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_046464873.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046478189.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Activation of ATR in response to replication stress"
XP_046482120.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046474621.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_046477607.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046492489.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046487724.1	4	Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-196741	"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046487852.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046471884.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_046465213.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046479046.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_046492349.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Non-integrin membrane-ECM interactions"
XP_046474247.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_046491888.1	14	KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-561	"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_046465122.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_046489707.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_046491347.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046478769.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046473104.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046483085.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046486802.1	5	MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_046469026.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046466548.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046482191.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_046481240.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_046487162.1	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_046464912.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046489532.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046466237.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046480562.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046478732.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046479024.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_046478831.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_046482676.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007	"mTOR signaling pathway";"DSCAM interactions";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events"
XP_046483926.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-912446	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination"
XP_046467928.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046489580.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046474723.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_046475625.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046492378.1	4	MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269;MetaCyc: PWY-5668	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I"
XP_046489967.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_046476032.1	5	MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_046473867.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_046469384.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046469082.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8934593	"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity"
XP_046485846.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670	"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Sialic acid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis"
XP_046489706.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_046480070.1	20	MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7858	"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II"
XP_046475985.1	3	Reactome: R-HSA-114608;Reactome: R-HSA-194313;Reactome: R-HSA-195399	"Platelet degranulation";"VEGF ligand-receptor interactions";"VEGF binds to VEGFR leading to receptor dimerization"
XP_046480384.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_046483733.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046477305.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046467487.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046481009.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046469181.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_046478116.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046488249.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046476651.1	5	Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012	"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046485152.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_046483056.1	17	MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7205	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation"
XP_046489154.1	8	KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1	"Galactose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis"
XP_046484490.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046484012.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046485992.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046484921.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046466563.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046468455.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_046467308.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_046469607.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046478311.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046466607.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399	"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_046482856.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046480022.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827	"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex"
XP_046469762.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046491794.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046476098.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046476335.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046487831.1	24	Reactome: R-HSA-165158;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-354192;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921	"Activation of AKT2";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Estrogen-stimulated signaling through PRKCZ";"Integrin signaling";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"RSK activation";"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation"
XP_046488294.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046484512.1	9	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_046486194.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_046465208.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046466476.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046469383.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046488522.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046489546.1	4	Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642	"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation"
XP_046491790.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046486536.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046481233.1	13	Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-139853	"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels"
XP_046472231.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046468137.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046472118.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_046493402.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_046467351.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-166058	"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_046481764.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046482445.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046480063.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046471787.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_046481413.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046484795.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046466677.1	15	Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579	"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange"
XP_046470986.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_046479082.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046491579.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046481599.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046486321.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_046476487.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046483247.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_046484685.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046481625.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046481771.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046491759.1	8	MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;Reactome: R-HSA-2426168	"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_046473437.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-437239	"Cilium Assembly";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1"
XP_046491648.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046481671.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046493246.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046492227.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046476639.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046464711.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046471672.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046491440.1	6	KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12	"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose metabolism"
XP_046475422.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-877300	"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"RAF activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling"
XP_046477962.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_046466686.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046486242.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046488365.1	10	Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508	"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_046466933.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046467036.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046473694.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046470723.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046480469.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_046480062.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046484000.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_046467059.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046471207.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_046482614.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046467941.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046479147.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046475299.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046473243.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046476719.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046467853.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
XP_046489964.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_046481552.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs"
XP_046485710.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_046493038.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046490483.1	12	KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4	"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Purine metabolism";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Purine metabolism";"Selenate reduction";"Sulfur metabolism";"Monobactam biosynthesis"
XP_046470284.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046484098.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_046485324.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046483134.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046473454.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046480685.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046473473.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046475448.1	7	Reactome: R-HSA-77111;KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074	"Synthesis of Ketone Bodies";"Valine, leucine and isoleucine degradation";"Peroxisomal protein import";"Geraniol degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Mevalonate degradation"
XP_046470527.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs"
XP_046488671.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046493183.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046470214.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046482016.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046471159.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_046489902.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046487819.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046479325.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046466762.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046470657.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046470624.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046467316.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046476582.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046476148.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046471065.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046489993.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046471887.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_046493120.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046479128.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046468057.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046483735.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046488781.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046477745.1	7	MetaCyc: PWY-5265;MetaCyc: PWY-6470;MetaCyc: PWY-6471;MetaCyc: PWY-6385;KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046481117.1	12	Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-5655302;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"Rho GTPase cycle";"Signaling by FGFR1 in disease";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046475552.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046472946.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-982772	"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling"
XP_046491147.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046477674.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046492499.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046484252.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046480055.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046475571.1	7	MetaCyc: PWY-7782;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-3385	"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Synthesis of PE";"Choline biosynthesis I"
XP_046479628.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046477315.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046469597.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046489833.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046467470.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046474528.1	3	Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100	"Carnitine synthesis";"Lysine degradation";"L-carnitine biosynthesis"
XP_046490603.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046471072.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046484858.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046479663.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_046484249.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046473108.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_046475300.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046473831.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046466386.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046470949.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046492927.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046475486.1	4	Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-198693	"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus"
XP_046483127.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046476625.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209	"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_046477324.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046477730.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_046483253.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_046493036.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046477997.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046468001.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046482830.1	9	Reactome: R-HSA-9646399;Reactome: R-HSA-8856825;Reactome: R-HSA-5627083;Reactome: R-HSA-8856828;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880	"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis";"RHO GTPases regulate CFTR trafficking";"Clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases"
XP_046464770.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046469609.1	3	KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
XP_046487143.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107	"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_046475858.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046468336.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_046470755.1	13	KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-2424491;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;KEGG: 04070+3.1.4.11	"Inositol phosphate metabolism";"FCERI mediated MAPK activation";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidylinositol signaling system"
XP_046466889.1	18	KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1	"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Tyrosine metabolism";"Sulfolactate degradation III";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Arginine biosynthesis";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis"
XP_046470982.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
XP_046486441.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046492745.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046467024.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_046468961.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046477763.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation"
XP_046479549.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046477964.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_046486563.1	15	Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580	"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence"
XP_046485998.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046476521.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046478225.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046481927.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046480092.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046487036.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046477940.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046492732.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046490433.1	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
XP_046474085.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046467096.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046482637.1	15	Reactome: R-HSA-8863795;Reactome: R-HSA-9665233;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9665244;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9652282;Reactome: R-HSA-9634285;Reactome: R-HSA-9664565;Reactome: R-HSA-1236382	"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"
XP_046480246.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046471036.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_046492623.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046488875.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046481882.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046490886.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046465872.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046483129.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046484091.1	33	Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-69656;Reactome: R-HSA-6782135	"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Cyclin A:Cdk2-associated events at S phase entry";"Dual incision in TC-NER"
XP_046477074.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046468482.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046474501.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046481887.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046468988.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_046484777.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046484147.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046480696.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046476661.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046476555.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046490139.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046483543.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_046487528.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_046468480.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046476053.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046476437.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046476985.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046485706.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046474176.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046489512.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_046486182.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046488753.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_046480093.1	5	MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_046476490.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046489490.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_046482815.1	9	Reactome: R-HSA-8856825;Reactome: R-HSA-9646399;Reactome: R-HSA-5689880;Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5627083;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Aggrephagy";"Ub-specific processing proteases";"Late endosomal microautophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"RHO GTPases regulate CFTR trafficking";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis"
XP_046473560.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046475450.1	7	MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111	"Mevalonate degradation";"Geraniol degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Peroxisomal protein import";"Synthesis of Ketone Bodies"
XP_046490389.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046475195.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046485510.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-8955332	"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Cilium Assembly";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin"
XP_046474516.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_046466123.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046483879.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046474431.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046467265.1	13	KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Hyaluronan uptake and degradation"
XP_046489357.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046479134.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis"
XP_046464839.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
XP_046480136.1	8	KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism"
XP_046485066.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046479771.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046489309.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046486152.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167246	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript"
XP_046488727.1	1	Reactome: R-HSA-156581	"Methylation"
XP_046474207.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046487092.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046474308.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046471669.1	7	Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-5663220;Reactome: R-HSA-201681;Reactome: R-HSA-4641258	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"WNT mediated activation of DVL";"PCP/CE pathway";"RHO GTPases Activate Formins";"TCF dependent signaling in response to WNT";"Degradation of DVL"
XP_046487624.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046487641.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046464758.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046486462.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046491297.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_046492604.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_046467049.1	8	KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27	"Cysteine and methionine metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_046490709.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046489475.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046488140.1	6	MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_046480680.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046491384.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_046478677.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046487619.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046485126.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine"
XP_046476957.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046471481.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046487632.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046475762.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046487848.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046472243.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046481597.1	10	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-442742;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257	"Thermogenesis";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"RSK activation"
XP_046479315.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046476138.1	17	Reactome: R-HSA-200425;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-196780	"Carnitine metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Jadomycin biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism"
XP_046473904.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046485367.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046468651.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046472784.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046484244.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046491115.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046474206.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046474930.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046482631.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046487606.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046474531.1	3	KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262;MetaCyc: PWY-6100	"Lysine degradation";"Carnitine synthesis";"L-carnitine biosynthesis"
XP_046487790.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046472299.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046480517.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046479314.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046490137.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_046482939.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_046493009.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046471041.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046464834.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046485701.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046481285.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046489708.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_046471667.1	7	Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-201688;Reactome: R-HSA-4086400	"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"WNT mediated activation of DVL";"PCP/CE pathway"
XP_046485019.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046470129.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046479379.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046490188.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046465754.1	7	Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;MetaCyc: PWY-7158	"Phenylketonuria";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V"
XP_046476982.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046478902.1	7	MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;Reactome: R-HSA-5578999	"Homoglutathione biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_046468180.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046477330.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046475773.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046477736.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046474646.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_046488815.1	57	Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783	"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome"
XP_046484447.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_046477646.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_046492122.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046486924.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_046485724.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046487450.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046490100.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle";"Inositol phosphate metabolism"
XP_046490023.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046492796.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_046478206.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_046480436.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-3214847	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"HATs acetylate histones"
XP_046475297.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046466363.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_046479217.1	9	MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.94	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism"
XP_046491348.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046488025.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046478879.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046468344.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_046466730.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66	"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism"
XP_046465536.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046491769.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_046478869.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_046491090.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046468268.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_046488907.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046479161.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046478341.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046474611.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_046480257.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046486191.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_046490626.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046484590.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046477228.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_046488686.1	13	KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Hyaluronan uptake and degradation"
XP_046467808.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046474217.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046493348.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_046483961.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046476652.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046490306.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046483606.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_046479389.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5857;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5855	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)"
XP_046493101.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046471446.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046477122.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046481880.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046489666.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046464755.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_046488926.1	6	MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_046492560.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046482458.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046475142.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046487192.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046492325.1	5	Reactome: R-HSA-6798695;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6	"Neutrophil degranulation";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism"
XP_046472011.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_046478192.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046478480.1	8	Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Activation of RAC1";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046486051.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046474471.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046483941.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046473864.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046473428.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046476501.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046471967.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046491143.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046482567.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046480930.1	4	Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_046485273.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_046488751.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046490163.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166	"Processive synthesis on the lagging strand";"Polymerase switching";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate"
XP_046471021.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046491986.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046480238.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046473721.1	12	Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167287	"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery"
XP_046474999.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046478490.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046487647.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046464969.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_046466294.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046469333.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046469548.1	3	KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
XP_046465615.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046490956.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046484923.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_046472916.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046478117.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046484093.1	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_046467223.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046479366.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation";"Neutrophil degranulation"
XP_046484238.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046468477.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046480541.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_046473593.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370	"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Galactose metabolism";"Galactose catabolism"
XP_046470238.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046476480.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046465955.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_046470240.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046486125.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-113418	"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex"
XP_046477337.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046470890.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046466786.1	12	KEGG: 04150+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"DCC mediated attractive signaling";"Relaxin signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046493178.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046469592.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046492189.1	15	Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723	"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation"
XP_046477402.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_046492657.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046483328.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046478018.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046492774.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046464832.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046487808.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046491296.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_046470477.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046475042.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046470301.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_046466722.1	6	Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66	"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_046490926.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046485328.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046477157.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046492735.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_046479497.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046475180.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046490256.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_046472919.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046471346.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_046478091.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046489372.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046493375.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046487784.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046478320.1	3	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046469346.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046480109.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046477645.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37	"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism"
XP_046468753.1	8	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046486936.1	9	MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_046470906.1	6	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427359	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression"
XP_046466006.1	56	Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733	"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_046491952.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_046492606.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_046468141.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_046477299.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046488955.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_046492344.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_046477714.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_046477121.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046477049.1	4	KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00052+3.1.3.9;KEGG: 00010+3.1.3.9	"Starch and sucrose metabolism";"Gluconeogenesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046477781.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046476260.1	22	Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_046466625.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046466004.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046488292.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046482896.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046481866.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046475871.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046470058.1	8	Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-6782210	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046475116.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046476308.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_046475865.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_046466735.1	4	MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23	"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism"
XP_046469160.1	11	Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986	"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2"
XP_046493373.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046465626.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_046478101.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046470577.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046479666.1	6	MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_046465096.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856828	"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis"
XP_046464933.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK"
XP_046480426.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046476715.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046482700.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_046490094.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046473717.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_046468966.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046482242.1	18	MetaCyc: PWY-7511;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901	"Protein ubiquitination";"Meiotic recombination";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs"
XP_046473542.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046487616.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046467743.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-72764	"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Methylation";"Eukaryotic Translation Termination"
XP_046478632.1	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222	"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_046472896.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046483434.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046471577.1	6	KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124	"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II"
XP_046468277.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-6785807;Reactome: R-HSA-452723;Reactome: R-HSA-2892245;Reactome: R-HSA-8986944;Reactome: R-HSA-2892247	"Deactivation of the beta-catenin transactivating complex";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation of pluripotent stem cells";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Transcriptional Regulation by MECP2";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"
XP_046483754.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046491835.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046467690.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_046469403.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046481416.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046468478.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046487260.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046487426.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_046480748.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046489799.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046465543.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_046476266.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046475383.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046466527.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_046480100.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046477966.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_046481012.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046467937.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046469189.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046487979.1	27	Reactome: R-HSA-4641262;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-8939902;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-5610785;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-195253;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;KEGG: 04151+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-5674400;Reactome: R-HSA-5467348;Reactome: R-HSA-399956;KEGG: 04714+2.7.11.1	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Relaxin signaling pathway";"mTOR signaling pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Regulation of RUNX2 expression and activity";"Human cytomegalovirus infection";"Degradation of GLI2 by the proteasome";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"B-WICH complex positively regulates rRNA expression";"GLI3 is processed to GLI3R by the proteasome";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Human papillomavirus infection";"Regulation of HSF1-mediated heat shock response";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"PI3K-Akt signaling pathway";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by AKT1 E17K in Cancer";"Truncations of AMER1 destabilize the destruction complex";"CRMPs in Sema3A signaling";"Thermogenesis"
XP_046468065.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_046480476.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046479512.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046475003.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046489699.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex"
XP_046467050.1	8	Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086	"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_046474620.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_046484850.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046467293.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046492600.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_046468570.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_046469302.1	5	Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939	"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)"
XP_046472830.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046479300.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-7238;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25	"Neutrophil degranulation";"Starch degradation II";"Sucrose biosynthesis II";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism"
XP_046466315.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_046475700.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_046470276.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_046472917.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046475441.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046481466.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046472936.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"RMTs methylate histone arginines"
XP_046467314.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046466726.1	6	Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66	"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_046469951.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046470203.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046468019.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046468878.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046476673.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_046479989.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_046474716.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress"
XP_046476005.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046473143.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046482495.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046477361.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_046480150.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_046469275.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046466590.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_046468778.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046488369.1	10	Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-1912408	"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation"
XP_046488925.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6922	"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_046489786.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046492782.1	5	Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787	"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Activation of SMO";"Hedgehog 'off' state"
XP_046482685.1	5	Reactome: R-HSA-168638;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"NOD1/2 Signaling Pathway";"DSCAM interactions";"mTOR signaling pathway";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
XP_046490316.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046487158.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046478262.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046480314.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046489337.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046478882.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046476812.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046478809.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_046473801.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046485997.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046481464.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046473313.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046470173.1	31	MetaCyc: PWY-8012;MetaCyc: PWY-5147;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-7746;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-7858;MetaCyc: PWY-6799;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-8049;MetaCyc: PWY-7723;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-6519	"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Pederin biosynthesis";"Bacterial bioluminescence";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I"
XP_046488309.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046467704.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046484949.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046469101.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN"
XP_046475285.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046486010.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046477524.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_046477994.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036	"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_046466450.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046476076.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046479547.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_046482001.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046473961.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-5626467	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs"
XP_046479085.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046470766.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046475550.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046491666.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"EPHB-mediated forward signaling"
XP_046483298.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_046485327.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046479466.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_046465907.1	32	Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695	"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events"
XP_046488945.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_046466899.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046468303.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046480353.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046480526.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320	"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation"
XP_046475956.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046468908.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046478887.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_046492264.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046487658.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046469235.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046465916.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046483384.1	5	KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891	"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)"
XP_046486038.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046479215.1	9	MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-7385	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)"
XP_046473609.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_046465757.1	7	KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;MetaCyc: PWY-7158;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1	"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Folate biosynthesis"
XP_046467644.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046481657.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046474949.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046484453.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_046470554.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046473859.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_046487463.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046478277.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046491026.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046465909.1	32	Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167158	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex"
XP_046489552.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046479007.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046492607.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_046472321.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046472957.1	7	KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis"
XP_046465694.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046478557.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046470990.1	4	KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_046490134.1	9	MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;KEGG: 00790+3.5.4.16	"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_046485088.1	11	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097	"Thermogenesis";"PI3K-Akt signaling pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_046476025.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046489695.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046488471.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_046471881.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046489409.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046479511.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046468982.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046478640.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-6824	"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Justicidin B biosynthesis"
XP_046478895.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257	"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion"
XP_046483797.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_046472148.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046487824.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046465788.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046487093.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046467739.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_046476778.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation"
XP_046480858.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_046480624.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046485189.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046487195.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046481530.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046475442.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046468447.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_046482634.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_046481388.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046493347.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_046490612.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046473146.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046480419.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046479664.1	6	MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900	"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_046483619.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046475376.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802946	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"RAF activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants"
XP_046479171.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046468569.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046477993.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046483655.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046466580.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046469781.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046469131.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046473094.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046480819.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"Neutrophil degranulation";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046469994.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046474891.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_046488368.1	10	Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-350054	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_046465777.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046469329.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046464903.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046476417.1	4	Reactome: R-HSA-72731;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_046491197.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046476580.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046493033.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046489306.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046485413.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046477460.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046479066.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046477969.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_046467226.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046473147.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046485959.1	7	Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-165181	"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB"
XP_046479600.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_046471353.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046467472.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046479124.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397	"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_046465223.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046468688.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_046479750.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046480131.1	14	Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-1474228;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695	"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Degradation of the extracellular matrix";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation"
XP_046469447.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046465565.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_046479353.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046472388.1	6	KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234	"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III"
XP_046491162.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_046491445.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-2467813	"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids"
XP_046490360.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_046486702.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046464914.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046484485.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046492594.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046480110.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046468488.1	27	Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-3232142	"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins"
XP_046467237.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046489550.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046485047.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046470596.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_046487713.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046492575.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046470331.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827	"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_046477779.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046489959.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_046466300.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046486923.1	5	Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3	"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)"
XP_046484950.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046486109.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046490180.1	52	Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-73762;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-76071;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-9018519;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-167158	"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex"
XP_046469997.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046488832.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046481867.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046484645.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046487407.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_046480102.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046471444.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046486000.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046483602.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_046472536.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046482804.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism"
XP_046482135.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702;Reactome: R-HSA-110329;Reactome: R-HSA-9657050;Reactome: R-HSA-9656255	"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged pyrimidine";"Defective OGG1 Localization";"Defective OGG1 Substrate Binding"
XP_046473183.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046487038.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046484791.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046490865.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046485969.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046466526.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_046472144.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046469178.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_046488293.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046475877.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046482569.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046479246.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046474834.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs"
XP_046481384.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046479875.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046486455.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046481082.1	18	MetaCyc: PWY-5913;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7117	"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Sulfolactate degradation III";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Arginine biosynthesis";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_046489525.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046485446.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046473700.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046471311.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046469653.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046481819.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046486647.1	8	Reactome: R-HSA-163754;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;Reactome: R-HSA-6791055;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;MetaCyc: PWY-5723	"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt"
XP_046478489.1	14	Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_046485849.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046484862.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_046481598.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046465218.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046489520.1	6	MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_046474748.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_046482468.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046469745.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046474434.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046487964.1	7	KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-6596;MetaCyc: PWY-5695	"Drug metabolism - other enzymes";"Purine metabolism";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation"
XP_046486052.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046469944.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046467516.1	8	KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372;MetaCyc: PWY-6580;MetaCyc: PWY-2301;MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-4661	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_046489354.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046476975.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046472043.1	10	Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587	"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)"
XP_046471976.1	7	MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10	"UMP biosynthesis I";"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Pyrimidine metabolism"
XP_046478590.1	15	Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated"
XP_046479682.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation"
XP_046484819.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046492500.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046484192.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046475485.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399	"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors"
XP_046464821.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046480802.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046489684.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_046472230.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046493035.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046479955.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046483210.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046471731.1	7	Reactome: R-HSA-1474151;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"One carbon pool by folate"
XP_046487042.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046472143.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046467231.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046464870.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046474305.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046485615.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046486664.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046469853.1	7	Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_046490887.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046471300.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046490382.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046475999.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_046465183.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046475776.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046482283.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046480477.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046492736.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-112043	"G-protein activation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events"
XP_046465336.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046482047.1	11	Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1989781	"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PPARA activates gene expression"
XP_046483535.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046488617.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046468472.1	3	Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-4608870	"Class B/2 (Secretin family receptors)";"PCP/CE pathway";"Asymmetric localization of PCP proteins"
XP_046477507.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046475926.1	11	Reactome: R-HSA-912694;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-432142;Reactome: R-HSA-388841;Reactome: R-HSA-210990;Reactome: R-HSA-877312;Reactome: R-HSA-389948;Reactome: R-HSA-9008059;Reactome: R-HSA-114604;Reactome: R-HSA-391160	"Regulation of IFNA signaling";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Platelet sensitization by LDL";"Costimulation by the CD28 family";"PECAM1 interactions";"Regulation of IFNG signaling";"PD-1 signaling";"Interleukin-37 signaling";"GPVI-mediated activation cascade";"Signal regulatory protein family interactions"
XP_046492323.1	6	Reactome: R-HSA-6785470;MetaCyc: PWY-6829;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;Reactome: R-HSA-6787450;MetaCyc: PWY-7286	"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_046478108.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046478803.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046482619.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046467812.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046482400.1	19	Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-975634	"Chylomicron remodeling";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Chylomicron assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Clathrin-mediated endocytosis";"VLDL clearance";"LDL clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Retinoid metabolism and transport"
XP_046483627.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046484882.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_046464840.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_046479023.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046488824.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046475548.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046484220.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046478559.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046473543.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046473258.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046475522.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955	"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"RAF activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_046491308.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046488167.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046468904.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046492493.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046487889.1	11	KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4	"Ether lipid metabolism";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Sphingolipid metabolism"
XP_046478236.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046481474.1	11	MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-3861;MetaCyc: PWY-7586;MetaCyc: PWY-6992;Reactome: R-HSA-446205;MetaCyc: PWY-7456	"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation"
XP_046482063.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046482498.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046481202.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046491482.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046475403.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046481181.1	10	KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13	"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione metabolism"
XP_046478916.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_046481158.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_046489940.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_046467548.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046478820.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046469750.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046493407.1	5	Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-5689877	"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Amyloid fiber formation";"Josephin domain DUBs"
XP_046465476.1	14	Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4	"Synthesis of PC";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism"
XP_046469023.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046493031.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046480247.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046484924.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_046476242.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046469635.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_046484867.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046467586.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_046489450.1	5	Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780	"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome"
XP_046482625.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046473604.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046488894.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046475567.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis"
XP_046493010.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046472720.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_046466601.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046479115.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046474992.1	14	MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667	"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_046491979.1	3	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway"
XP_046482211.1	11	Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270	"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046489011.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046479632.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046473425.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046488139.1	6	Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-7761	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)"
XP_046481653.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046485070.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046466481.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046468779.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046491092.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046480688.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046478092.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046468544.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046476922.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046485443.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_046472047.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046475805.1	5	MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7176	"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis"
XP_046486090.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
XP_046488193.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046465079.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_046489566.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_046479092.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046474257.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_046465143.1	5	MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41	"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system"
XP_046484612.1	4	MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062	"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol"
XP_046493126.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046476051.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046475873.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046487622.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046485641.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046488672.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046472897.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046485224.1	18	Reactome: R-HSA-1482801;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783	"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation"
XP_046473581.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_046476947.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046482570.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046484509.1	9	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046492356.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046488323.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_046472061.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046469514.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046478210.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_046481985.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046487473.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046478928.1	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_046489548.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046482886.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_046470880.1	5	Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225	"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_046487830.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046485796.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046485657.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_046483912.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046465178.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046482885.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046479617.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046465083.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_046491370.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_046491173.1	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3"
XP_046484551.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_046479919.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046472824.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046480045.1	11	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
XP_046490154.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046488207.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Post-translational protein phosphorylation"
XP_046487039.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046475570.1	7	Reactome: R-HSA-1483191;MetaCyc: PWY-7886;MetaCyc: PWY-7782;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82	"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism"
XP_046481253.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_046474974.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046464931.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_046472449.1	3	KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate"
XP_046475562.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_046484714.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046464843.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK"
XP_046488828.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046465619.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046469695.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046467123.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046488253.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046481160.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046492313.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-901032	"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)"
XP_046480305.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046472687.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_046487156.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046480393.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_046466729.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane"
XP_046476648.1	5	Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4	"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism"
XP_046489622.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046475287.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046481666.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046464838.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
XP_046473360.1	7	MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753	"UMP biosynthesis II";"UMP biosynthesis III";"Drug metabolism - other enzymes";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_046465554.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046478127.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046477222.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_046484947.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046466362.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_046465577.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046484794.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046466252.1	17	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs"
XP_046492749.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046490099.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046492938.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046487191.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046476944.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046480941.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111459	"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage"
XP_046480623.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_046467553.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046480317.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046487085.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046464925.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046485821.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046464935.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046465516.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_046471557.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046466723.1	6	KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_046473623.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046471977.1	6	Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-2173788	"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling"
XP_046488691.1	4	MetaCyc: PWY-7546;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_046477971.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_046484164.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_046488625.1	17	MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Purine metabolism"
XP_046470564.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046489485.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046473557.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_046489911.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046479649.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_046471992.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046469232.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"PKA activation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_046470147.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046480432.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
XP_046487460.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_046465599.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_046469376.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046478425.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046467705.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046473217.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046489518.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_046466111.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046486538.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046489216.1	4	KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046469921.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_046470895.1	5	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism"
XP_046488848.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_046477342.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046478412.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046479641.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046481870.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046490217.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046489672.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046480420.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046474650.1	7	Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034	"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np"
XP_046475523.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination"
XP_046491281.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046484948.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046492333.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs"
XP_046479505.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_046465312.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046488289.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046478126.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046475703.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046469335.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-5656169	"Peroxisomal protein import";"Termination of translesion DNA synthesis"
XP_046480427.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046486771.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046485558.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_046483857.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046477946.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_046470938.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_046477511.1	10	Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-8936459	"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046468698.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046491997.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
XP_046469228.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_046466588.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_046474205.1	5	MetaCyc: PWY-7782;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins"
XP_046490463.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_046479357.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046477140.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046475321.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046492599.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046470084.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046478265.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046479370.1	5	Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_046467376.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_046483479.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046483042.1	13	MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-6383;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-5123	"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_046475719.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events"
XP_046467251.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046491803.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_046488258.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046492652.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046488880.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046470085.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046466241.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_046491583.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046473949.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046485902.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_046491632.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046469799.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046488596.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046469380.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046472592.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046481662.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046469256.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368082	"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression"
XP_046474975.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046475323.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046484718.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046492576.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046488202.1	6	Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077;MetaCyc: PWY-6906;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25	"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism"
XP_046477766.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597	"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events"
XP_046487097.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046466310.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_046480371.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046487010.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046487660.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046491758.1	8	Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_046483296.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_046471410.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_046465249.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-168315;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Inhibition of Host mRNA Processing and RNA Silencing";"Processing of Intronless Pre-mRNAs"
XP_046468022.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046466749.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046481393.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046469976.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736	"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors"
XP_046485879.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-2151201	"HATs acetylate histones";"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis"
XP_046484108.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046468278.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-2892247;Reactome: R-HSA-8986944;Reactome: R-HSA-2892245;Reactome: R-HSA-452723;Reactome: R-HSA-6785807	"Deactivation of the beta-catenin transactivating complex";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Transcriptional Regulation by MECP2";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Transcriptional regulation of pluripotent stem cells";"Interleukin-4 and Interleukin-13 signaling"
XP_046490884.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046481975.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_046472870.1	14	KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409	"Ether lipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_046473369.1	7	KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7790	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis I";"UMP biosynthesis II"
XP_046475381.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046479992.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046476333.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046491829.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046477050.1	4	KEGG: 00010+3.1.3.9;KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Gluconeogenesis"
XP_046492777.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046491304.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_046486106.1	29	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-73776	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape"
XP_046478819.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_046475768.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Ether lipid metabolism"
XP_046485021.1	57	Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5668541	"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway"
XP_046475925.1	11	Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-877312;Reactome: R-HSA-9008059;Reactome: R-HSA-391160;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-210990;Reactome: R-HSA-432142	"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling";"PD-1 signaling";"Regulation of IFNG signaling";"Interleukin-37 signaling";"Signal regulatory protein family interactions";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"PECAM1 interactions";"Platelet sensitization by LDL"
XP_046476064.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins"
XP_046474718.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_046491116.1	6	KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis"
XP_046492753.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046480851.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_046473176.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046479288.1	24	Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G-protein activation";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_046477628.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046492976.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046480569.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046478481.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway"
XP_046488360.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs"
XP_046469366.1	10	KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042	"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis IV (plant cytosol)"
XP_046475806.1	11	Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type"
XP_046471337.1	31	MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-8012;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-6519;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-5994;MetaCyc: PWY-7858;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-7664;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388	"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Pederin biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)"
XP_046465736.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046478306.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_046474915.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046484197.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046475211.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_046482302.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_046475641.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046488956.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_046484329.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046481095.1	5	KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532	"Pyrimidine metabolism";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)"
XP_046488595.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046468416.1	15	Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-9603505	"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"NTRK3 as a dependence receptor"
XP_046485921.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046479845.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046489414.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_046471397.1	12	MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-6309;MetaCyc: PWY-1187;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-601	"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan"
XP_046488411.1	8	Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism"
XP_046475171.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046482547.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046484845.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_046465648.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_046478083.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)"
XP_046475000.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046490955.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046483847.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7858	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II"
XP_046482034.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046483545.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_046467787.1	13	Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-182218	"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"LDL clearance";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation"
XP_046476049.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046490171.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046481827.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046469744.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046487609.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046483955.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046478023.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_046488092.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211	"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling"
XP_046484974.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046475631.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046466842.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046489471.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046479661.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046483805.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_046467549.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046475205.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046484622.1	12	MetaCyc: PWY-6613;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;Reactome: R-HSA-73817;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Purine metabolism"
XP_046473127.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_046483209.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046485330.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046481762.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046492121.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046466376.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_046482616.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046484017.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_046485136.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046464922.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_046485648.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_046479960.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046473782.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046490731.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046479372.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046477338.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046483080.1	10	KEGG: 00250+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-5022;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-6537;Reactome: R-HSA-916853;KEGG: 00410+2.6.1.19;MetaCyc: PWY-4321	"Alanine, aspartate and glutamate metabolism";"Butanoate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation V";"Propanoate metabolism";"4-aminobutanoate degradation I";"4-aminobutanoate degradation II";"Degradation of GABA";"beta-Alanine metabolism";"L-glutamate degradation IV"
XP_046478426.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046470929.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046472097.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046476482.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046491804.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_046484298.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046466508.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046473866.1	42	Reactome: R-HSA-5617472;Reactome: R-HSA-5693565;Reactome: R-HSA-977225;Reactome: R-HSA-2299718;Reactome: R-HSA-5625886;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-73728;Reactome: R-HSA-9616222;Reactome: R-HSA-9610379;Reactome: R-HSA-3214842;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-110328;Reactome: R-HSA-212300;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-2559580;Reactome: R-HSA-8939236;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5334118;Reactome: R-HSA-201722;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-3214841;Reactome: R-HSA-3214815;Reactome: R-HSA-606279;Reactome: R-HSA-912446	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Amyloid fiber formation";"Condensation of Prophase Chromosomes";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Opening";"Transcriptional regulation of granulopoiesis";"HCMV Late Events";"HDMs demethylate histones";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PRC2 methylates histones and DNA";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Oxidative Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"DNA methylation";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"HCMV Early Events";"HATs acetylate histones";"G2/M DNA damage checkpoint";"PKMTs methylate histone lysines";"HDACs deacetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic recombination"
XP_046479232.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_046477989.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046491991.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046486192.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046488215.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046479576.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046481259.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046470330.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_046465228.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046467933.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046471450.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-5687128;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9634638;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"MAPK6/MAPK4 signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Separation of Sister Chromatids"
XP_046466760.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046484111.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046492729.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046465245.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046465992.1	15	Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence"
XP_046483186.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046485713.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_046482879.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046470447.1	3	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_046479003.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046470729.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046491091.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046480538.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046465085.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_046491295.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_046485294.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_046483477.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046469851.1	7	Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2	"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism"
XP_046476792.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046476395.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046469930.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046485252.1	6	KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632	"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_046486865.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046465499.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046482165.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_046480215.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046489935.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046467208.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_046482582.1	10	MetaCyc: PWY-6369;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6554	"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_046477060.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046477778.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144	"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_046468920.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046473315.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046474993.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046466503.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046492517.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046467294.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046472323.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Gap junction assembly";"Cilium Assembly";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_046475746.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046476104.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046486458.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046488363.1	10	Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408	"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation"
XP_046484256.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046471956.1	6	Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_046477334.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046485297.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046481654.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046486323.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_046479348.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation";"Neutrophil degranulation"
XP_046492595.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046469409.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046492571.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Mitotic Prometaphase"
XP_046491586.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046465214.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046487298.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046468034.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676	"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle"
XP_046482701.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_046486542.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781	"Circadian Clock";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"RORA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"PPARA activates gene expression"
XP_046492369.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046474086.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046474428.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events"
XP_046480424.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046466478.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046489961.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_046484209.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046483333.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046483855.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381033;Reactome: R-HSA-1655829	"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046484905.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046478804.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_046486438.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046480125.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046477599.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046472233.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046476255.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046473804.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046475484.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_046491074.1	17	Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607	"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends"
XP_046465474.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_046487620.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046475555.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046470299.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_046466936.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046479102.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046491299.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_046491233.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046484355.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_046468523.1	13	KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416482	"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"PI3K-Akt signaling pathway";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events"
XP_046491491.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_046485253.1	6	Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis"
XP_046487437.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_046468777.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046491813.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046465932.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046477787.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046482405.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046488934.1	6	MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-3341	"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)"
XP_046491420.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046487573.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Chylomicron remodeling";"Chylomicron assembly";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"VLDL clearance";"Clathrin-mediated endocytosis";"VLDL assembly";"Post-translational protein phosphorylation";"LDL clearance";"Scavenging by Class A Receptors"
XP_046473459.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046489972.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-195253	"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex"
XP_046486822.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046485063.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046485725.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046488118.1	5	Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111469	"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC, XIAP-regulated apoptotic response"
XP_046480101.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046485437.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046464868.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046474310.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046490417.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046480690.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046489842.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046478513.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046479509.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046470597.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_046471176.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046479319.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046479125.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696397	"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Termination of translesion DNA synthesis";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_046473465.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046479506.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046482401.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046491088.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-2453864	"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Neutrophil degranulation";"Amyloid fiber formation";"Retinoid cycle disease events"
XP_046490959.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046467530.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046488260.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046491555.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046466546.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046474757.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046483972.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_046483028.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046486055.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046491591.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046477767.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993	"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors"
XP_046466448.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046472757.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046488913.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046487176.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_046488291.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046478880.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046465478.1	14	MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4	"Anandamide biosynthesis II";"Ether lipid metabolism";"Synthesis of PC";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Sphingolipid metabolism"
XP_046469248.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046481664.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046481669.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046473333.1	6	KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_046490136.1	4	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions"
XP_046466685.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046479067.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046487274.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046488530.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_046492658.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046488737.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046478744.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046479520.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046485715.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046466109.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_046493121.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046468006.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046469758.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046490157.1	13	MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-7909;KEGG: 00670+6.3.4.3;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030	"Folate transformations II (plants)";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III"
XP_046481157.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046467258.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046493384.1	10	Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111457	"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria"
XP_046483628.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046471991.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046486012.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046472793.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046485295.1	5	KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046485354.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046483812.1	34	Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-9639288;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854	"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amino acids regulate mTORC1";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_046489486.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_046483325.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046481751.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046481976.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_046482488.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046465141.1	5	MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046489853.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046469334.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046478899.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Separation of Sister Chromatids"
XP_046484621.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046480474.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046470547.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046480425.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046470451.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_046489411.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_046491581.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046471174.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785	"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"GLI3 is processed to GLI3R by the proteasome"
XP_046479022.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_046492496.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046469130.1	5	KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_046489488.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_046465522.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046477985.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724	"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046465597.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_046464771.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046475907.1	10	KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 04150+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04151+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.153	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"PI3K-Akt signaling pathway";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_046471465.1	6	Reactome: R-HSA-5654706;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712	"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling"
XP_046492561.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046469015.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046478783.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046476987.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046482630.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046478898.1	33	Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-159236	"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"snRNP Assembly";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046488299.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046476193.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046478745.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046470153.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046481754.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046470011.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046475196.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046465774.1	6	MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356	"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine salvage IV (yeast)"
XP_046479027.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_046471069.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_046487886.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761	"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_046466303.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046476001.1	6	MetaCyc: PWY-6363;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183	"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_046477712.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_046471864.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046481510.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation"
XP_046491685.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_046469326.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046488091.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568	"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase"
XP_046479028.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046472813.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046478493.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046465871.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046476791.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046490383.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046474313.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046492260.1	9	Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER"
XP_046477321.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046484092.1	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_046465184.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046479199.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"HIV Transcription Initiation"
XP_046476864.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046475302.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046493351.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046464779.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046468910.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046471480.1	3	KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism"
XP_046482101.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046470156.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046489722.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046473324.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046490421.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046486736.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046465227.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046483902.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046490333.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_046480711.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046479673.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-450408	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Deadenylation of mRNA";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_046488563.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_046491712.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_046478993.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046466511.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046492679.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046481957.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046484738.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046483385.1	5	MetaCyc: PWY-7560;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7	"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiamine metabolism"
XP_046465047.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046473003.1	5	Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-6798695	"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation"
XP_046488185.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046476570.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046476014.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046467375.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_046477992.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_046476722.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046492739.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_046472345.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046492315.1	6	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269	"Synthesis of PG";"Synthesis of PA";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II"
XP_046492057.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_046475039.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046480695.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_046472100.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046480428.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046473458.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046475831.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046488584.1	8	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Caspase activation via Dependence Receptors in the absence of ligand";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046473358.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_046480518.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046481182.1	10	KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13	"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism"
XP_046478921.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_046491552.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046489837.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046477594.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_046482073.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046492748.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046489750.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_046465248.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-168315	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Inhibition of Host mRNA Processing and RNA Silencing"
XP_046476656.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046488014.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046479527.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_046492047.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046480128.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046474755.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046467861.1	18	KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;Reactome: R-HSA-499943;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7227	"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_046465174.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046484803.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046488502.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_046469927.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046466676.1	15	Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks"
XP_046464848.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_046481490.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_046465514.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_046471460.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_046482223.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046476332.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046486452.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_046472242.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046486531.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046480818.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling"
XP_046469765.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046478825.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046477752.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046466525.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_046473364.1	7	MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753	"UMP biosynthesis II";"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_046471761.1	19	KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-561;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37	"Pyruvate metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methane metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms"
XP_046482613.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046465257.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046471989.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_046481952.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046489104.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2	"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_046465029.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046492776.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046472930.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695	"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling"
XP_046464724.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046464981.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046481476.1	11	MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-5659;MetaCyc: PWY-882;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7586;MetaCyc: PWY-6992;Reactome: R-HSA-446205;MetaCyc: PWY-7456	"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation"
XP_046468641.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046485288.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046486068.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046484647.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046482185.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046483720.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_046469826.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046470969.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046466547.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046474832.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_046470283.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046489937.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046470246.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046482442.1	5	Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413	"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression"
XP_046482505.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046488966.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046478298.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046484975.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046487682.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046476647.1	5	Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-8963693	"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism"
XP_046488964.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046481475.1	11	Reactome: R-HSA-446205;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-3861;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916	"Synthesis of GDP-mannose";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)"
XP_046481652.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046491599.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046475176.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_046481638.1	7	Reactome: R-HSA-6804114;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-69231	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Cyclin D associated events in G1"
XP_046484614.1	25	Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Gap junction assembly";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins"
XP_046477125.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046486102.1	9	MetaCyc: PWY-6142;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism"
XP_046485076.1	11	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046481424.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046488588.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046482699.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_046486510.1	12	MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-6978	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II"
XP_046474109.1	9	Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535	"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer"
XP_046478667.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5	"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Propanoate metabolism"
XP_046472768.1	3	MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_046489204.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046469435.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046467317.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046477624.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends"
XP_046477958.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046476978.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046476635.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046484984.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046489586.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_046492656.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046490281.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046479976.1	8	Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation"
XP_046482991.1	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;MetaCyc: PWY-7250;Reactome: R-HSA-1362409	"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis"
XP_046470677.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046490558.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_046471431.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046482990.1	11	MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7268;MetaCyc: PWY-7124;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-6549	"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III"
XP_046475113.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046467666.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046466597.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046479132.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_046491999.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_046474916.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046468703.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_046484919.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_046489843.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046475959.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046481601.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_046468283.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046482236.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046470265.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046490669.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046466784.1	12	Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"NRAGE signals death through JNK"
XP_046478771.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046473599.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_046474950.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046469084.1	16	Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580	"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence"
XP_046468782.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046481872.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046471380.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046486659.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046484191.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046488622.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism"
XP_046492680.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046465068.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046465016.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis"
XP_046476940.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046489053.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_046467122.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046491657.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_046471445.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046475193.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046479127.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046470152.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046476282.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_046476637.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046477343.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046468888.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046473918.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046484233.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046474844.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_046482209.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046481628.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-159230	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA"
XP_046467177.1	7	MetaCyc: PWY-7838;MetaCyc: PWY-7841;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7839	"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis"
XP_046488605.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046493125.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046493104.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046464836.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_046489013.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046466550.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046486203.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046476525.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046472333.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046474837.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_046470047.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046490419.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046471430.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046487644.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046485511.1	26	Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-6811436	"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Cilium Assembly";"Mitotic Prometaphase";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046492067.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046470468.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation"
XP_046469194.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046474177.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046475529.1	7	Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_046481140.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-2565942;Reactome: R-HSA-2467813;Reactome: R-HSA-380284;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-5663220;Reactome: R-HSA-380270	"Resolution of Sister Chromatid Cohesion";"Regulation of PLK1 Activity at G2/M Transition";"Separation of Sister Chromatids";"Loss of proteins required for interphase microtubule organization from the centrosome";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes"
XP_046492342.1	37	Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-9639288;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-204005;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-983170;Reactome: R-HSA-180910;Reactome: R-HSA-9648025	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Amino acids regulate mTORC1";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"COPII-mediated vesicle transport";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation"
XP_046465805.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046489682.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046490922.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046485647.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_046484836.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046479684.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation"
XP_046478107.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046488921.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046483806.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_046469549.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_046474029.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046478748.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046472350.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-168276	"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways"
XP_046490757.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046479383.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046486648.1	8	MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791055;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;Reactome: R-HSA-163754	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Insulin effects increased synthesis of Xylulose-5-Phosphate"
XP_046489467.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046480716.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046479467.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046482037.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046482584.1	10	MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554	"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_046490096.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046474606.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046489023.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_046480598.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_046474565.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_046466852.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_046475379.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046480681.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046471559.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046491664.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046476136.1	17	Reactome: R-HSA-196780;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744	"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Jadomycin biosynthesis";"Pyruvate metabolism";"Candicidin biosynthesis";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Glyoxylate assimilation"
XP_046474377.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2	"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism"
XP_046486047.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046491499.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046482382.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_046465118.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism"
XP_046481516.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_046490597.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046475257.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046490756.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046464737.1	29	Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination"
XP_046483038.1	13	MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-7721;MetaCyc: PWY-6859;MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7410;MetaCyc: PWY-7182	"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I"
XP_046478994.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046477972.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_046474480.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046485820.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046491190.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046466415.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046482202.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046490277.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046475859.1	5	MetaCyc: PWY-6853;Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88	"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism"
XP_046487628.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_046467955.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_046491357.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_046473188.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046487333.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_046472893.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046486004.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046471928.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_046491512.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046468923.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046479799.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_046475698.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046489483.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046484221.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_046467022.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046484893.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046487983.1	27	Reactome: R-HSA-5467337;Reactome: R-HSA-3371453;Reactome: R-HSA-5358747;KEGG: 04714+2.7.11.1;Reactome: R-HSA-399956;Reactome: R-HSA-5467348;KEGG: 04151+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-5674400;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;KEGG: 05165+2.7.11.1;Reactome: R-HSA-195253;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5610785;Reactome: R-HSA-5250924;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4641262;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;KEGG: 05163+2.7.11.1	"APC truncation mutants have impaired AXIN binding";"Regulation of HSF1-mediated heat shock response";"S33 mutants of beta-catenin aren't phosphorylated";"Thermogenesis";"CRMPs in Sema3A signaling";"Truncations of AMER1 destabilize the destruction complex";"PI3K-Akt signaling pathway";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by AKT1 E17K in Cancer";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Degradation of beta-catenin by the destruction complex";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"GLI3 is processed to GLI3R by the proteasome";"B-WICH complex positively regulates rRNA expression";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"mTOR signaling pathway";"Relaxin signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Human cytomegalovirus infection"
XP_046484350.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490	"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation"
XP_046482102.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046465219.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046486511.1	12	MetaCyc: PWY-6978;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5871;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-5873	"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_046472825.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046466284.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_046481103.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_046490713.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036	"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_046476583.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046467116.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046482819.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-9646399;Reactome: R-HSA-8856825	"RHO GTPases regulate CFTR trafficking";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Late endosomal microautophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis"
XP_046477281.1	12	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_046468179.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046485631.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046468017.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046485712.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046486879.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046488108.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046488657.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046491089.1	6	Reactome: R-HSA-2453864;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171	"Retinoid cycle disease events";"Amyloid fiber formation";"Neutrophil degranulation";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions"
XP_046486461.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046474927.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_046481059.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046481189.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046481665.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046469280.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046490420.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046472772.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046482536.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046466299.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046483135.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046485617.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046485081.1	11	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097	"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_046487147.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822	"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_046469336.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_046489721.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046493234.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046479009.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046472660.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046482419.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046478491.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046470070.1	14	KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-1622;MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-3661;MetaCyc: PWY-5497	"Cyanoamino acid metabolism";"Folate transformations I";"Formaldehyde assimilation I (serine pathway)";"Folate transformations II (plants)";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"One carbon pool by folate";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Metabolism of folate and pterines";"Glycine betaine degradation I";"Purine nucleobases degradation II (anaerobic)"
XP_046486058.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046486027.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046487978.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_046468625.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046484873.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456	"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation"
XP_046491763.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_046486001.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046469327.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046471628.1	13	Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-450302;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-937072	"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046481238.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_046480205.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046485939.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_046471683.1	9	Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68689	"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex"
XP_046471201.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_046473818.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046480672.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046470444.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046466375.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_046489970.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337	"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding"
XP_046479954.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046466172.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046477294.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046486446.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_046483063.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046469800.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046466753.1	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
XP_046467678.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346	"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of DVL";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis"
XP_046475380.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046489107.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046484979.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046473692.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046487985.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046469065.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046492386.1	24	Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-437239	"Gap junction assembly";"Cilium Assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1"
XP_046470878.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656237	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2"
XP_046492003.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046467942.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046470571.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046486871.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046478746.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_046486775.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046467652.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046492728.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046471934.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046488414.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_046475482.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399	"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors"
XP_046472140.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046481830.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046488558.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046478427.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046473356.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046491067.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_046491305.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_046483243.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046480182.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046470287.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_046471001.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046479751.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046470130.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046469372.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
XP_046482414.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_046491534.1	4	MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906	"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_046479969.1	8	MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_046487089.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046476416.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046475528.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046476943.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046484554.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_046492746.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046471360.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_046474316.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046480129.1	14	Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695	"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation"
XP_046474127.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231	"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046476852.1	6	Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15	"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism"
XP_046476747.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046473323.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046489638.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046490168.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046488829.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046481821.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046490578.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046482969.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_046473955.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046488087.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046471616.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046467056.1	7	Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
XP_046489628.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046471220.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046485694.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046484494.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046487710.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046465956.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_046468412.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_046486580.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046474787.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-442720	"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_046491435.1	6	MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism"
XP_046492289.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_046479805.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism"
XP_046485082.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_046481618.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046490613.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046474315.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046467332.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046470502.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046471412.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_046466851.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046472411.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046473148.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046487040.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046473128.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_046492653.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046476984.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046486765.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046481324.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_046492585.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_046492084.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_046466882.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_046476716.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_046471726.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_046469756.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046476224.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046475475.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000	"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Long-term potentiation";"RAF/MAP kinase cascade";"RAF activation"
XP_046484303.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046478989.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_046472225.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046465470.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes"
XP_046474156.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046484203.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046483329.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046474289.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046482019.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046474120.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046470373.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046470225.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046491099.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_046490560.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_046476641.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046489510.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046482947.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_046471470.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046477018.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046493366.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046468598.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_046490885.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046486315.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_046480564.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046475404.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-438066	"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"RAF activation";"Long-term potentiation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_046481453.1	6	MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;Reactome: R-HSA-74259	"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation II";"Purine catabolism"
XP_046471932.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046485628.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046482868.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_046471521.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046485441.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046486371.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046476298.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046483300.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_046491530.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046488912.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046478854.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_046474954.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes"
XP_046483699.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046470942.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-114608	"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation"
XP_046478992.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046478728.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046491900.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_046475293.1	56	Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5668541	"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway"
XP_046487420.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_046482104.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046486737.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046487149.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822	"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_046491433.1	6	Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12	"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_046483704.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_046468894.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046480508.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism"
XP_046468334.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_046473693.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046477741.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5537;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5	"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes"
XP_046476492.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046477154.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046467854.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
XP_046472057.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017	"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6"
XP_046483299.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_046482881.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046473921.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046475577.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046491998.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_046476397.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046481252.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_046471838.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_046473598.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046477980.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046473113.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046487469.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_046468844.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_046474808.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046472349.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046474405.1	5	Reactome: R-HSA-917937;Reactome: R-HSA-2173789;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-8856825	"Iron uptake and transport";"TGF-beta receptor signaling activates SMADs";"Neddylation";"UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis"
XP_046487646.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046479521.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046489868.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_046474182.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046492215.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)"
XP_046475830.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046465162.1	10	Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_046476205.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046467099.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046492580.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046471539.1	13	Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-450302;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-975163	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
XP_046489491.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046472045.1	10	MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II"
XP_046483303.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046466282.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-176409	"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_046475337.1	5	Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749	"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_046471348.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046479182.1	7	Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580	"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"HCMV Early Events";"Oxidative Stress Induced Senescence"
XP_046487173.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046468626.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046470941.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-114608	"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation"
XP_046489973.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221	"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway"
XP_046491704.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046468546.1	25	Reactome: R-HSA-8951911;Reactome: R-HSA-8939247;Reactome: R-HSA-8941284;Reactome: R-HSA-8941333;Reactome: R-HSA-8935964;Reactome: R-HSA-8939246;Reactome: R-HSA-8934593;Reactome: R-HSA-8931987;Reactome: R-HSA-9616222;Reactome: R-HSA-8941858;Reactome: R-HSA-8951936;Reactome: R-HSA-8878166;Reactome: R-HSA-8940973;Reactome: R-HSA-8939902;Reactome: R-HSA-8949275;Reactome: R-HSA-8939242;Reactome: R-HSA-8939243;Reactome: R-HSA-8941326;Reactome: R-HSA-8939245;Reactome: R-HSA-8939236;Reactome: R-HSA-8877330;Reactome: R-HSA-9018519;Reactome: R-HSA-8941332;Reactome: R-HSA-8936459;Reactome: R-HSA-8939256	"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates estrogen receptor mediated transcription";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX3 expression and activity";"RUNX3 regulates p14-ARF";"Transcriptional regulation by RUNX2";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX2 expression and activity";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Estrogen-dependent gene expression";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in WNT signaling"
XP_046488959.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_046470567.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046471792.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046468296.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046477544.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046473817.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046466281.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174084	"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_046482002.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046492487.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046472360.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046469324.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046478816.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_046469039.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046491802.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_046493195.1	8	Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_046484086.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046487696.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_046479391.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046470481.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046470230.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046475032.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046480224.1	4	MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_046491760.1	8	Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174	"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)"
XP_046475054.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046471861.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046480071.1	20	MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7858	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II"
XP_046485527.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046480408.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_046481748.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046489599.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046479966.1	8	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_046493358.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046473250.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046477894.1	9	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-3642279;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3645790	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"TGFBR2 MSI Frameshift Mutants in Cancer";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGFBR2 Kinase Domain Mutants in Cancer"
XP_046480597.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68962	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex"
XP_046484617.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_046469203.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357	"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1"
XP_046483738.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046476885.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046482940.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046481871.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046475181.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046480050.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046474312.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046478877.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_046480581.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_046469425.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046467457.1	5	Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_046492747.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046487015.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046484328.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046478150.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046477750.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046468301.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046480064.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046491313.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046474333.1	4	KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9	"beta-Alanine metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism"
XP_046470725.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046479317.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046465935.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_046465423.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_046465354.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046483506.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37	"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism"
XP_046469858.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046492752.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046487974.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046485444.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046483029.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046480678.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046470443.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046470840.1	7	Reactome: R-HSA-74217;MetaCyc: PWY-6610;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6605;MetaCyc: PWY-7805;Reactome: R-HSA-6798695;MetaCyc: PWY-7807	"Purine salvage";"Adenine salvage";"Purine metabolism";"Adenine and adenosine salvage II";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation";"Glyphosate degradation III"
XP_046482115.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046479298.1	7	MetaCyc: PWY-7238;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25	"Sucrose biosynthesis II";"Starch degradation II";"Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism"
XP_046466074.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046484648.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046480370.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046483705.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_046481777.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046469192.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046470598.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046487465.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_046487510.1	39	Reactome: R-HSA-2219530;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-2033514;Reactome: R-HSA-5654689;Reactome: R-HSA-5654704;Reactome: R-HSA-5654219;Reactome: R-HSA-5654221;Reactome: R-HSA-5654695;Reactome: R-HSA-5654687;Reactome: R-HSA-109704;Reactome: R-HSA-5654732;Reactome: R-HSA-2033519;Reactome: R-HSA-190375;Reactome: R-HSA-5654228;Reactome: R-HSA-5658623;Reactome: R-HSA-5654733;Reactome: R-HSA-5673001;Reactome: R-HSA-5654726;Reactome: R-HSA-5654693;Reactome: R-HSA-5654688;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-190371;Reactome: R-HSA-5654710;Reactome: R-HSA-190322;Reactome: R-HSA-1839122;Reactome: R-HSA-5654699;Reactome: R-HSA-5655253;Reactome: R-HSA-5654712;Reactome: R-HSA-5654720;Reactome: R-HSA-5654719;Reactome: R-HSA-190373;Reactome: R-HSA-5654227;Reactome: R-HSA-5655302;Reactome: R-HSA-8853338;Reactome: R-HSA-5654727;Reactome: R-HSA-1839130;Reactome: R-HSA-190372	"Constitutive Signaling by Aberrant PI3K in Cancer";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"FGFR3 mutant receptor activation";"PI-3K cascade:FGFR1";"SHC-mediated cascade:FGFR3";"Phospholipase C-mediated cascade: FGFR1";"Phospholipase C-mediated cascade, FGFR2";"PI-3K cascade:FGFR2";"Downstream signaling of activated FGFR1";"PI3K Cascade";"Negative regulation of FGFR3 signaling";"Activated point mutants of FGFR2";"FGFR2c ligand binding and activation";"Phospholipase C-mediated cascade, FGFR4";"FGFRL1 modulation of FGFR1 signaling";"Negative regulation of FGFR4 signaling";"RAF/MAP kinase cascade";"Negative regulation of FGFR1 signaling";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR1";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FGFR3b ligand binding and activation";"PI-3K cascade:FGFR3";"FGFR4 ligand binding and activation";"Signaling by activated point mutants of FGFR1";"SHC-mediated cascade:FGFR2";"Signaling by FGFR2 in disease";"FRS-mediated FGFR4 signaling";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR4";"FGFR1c ligand binding and activation";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR1 in disease";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR2 signaling";"Signaling by activated point mutants of FGFR3";"FGFR3c ligand binding and activation"
XP_046473438.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Cilium Assembly";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_046480791.1	6	Reactome: R-HSA-76071;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;Reactome: R-HSA-6807505;KEGG: 00740+3.1.3.2;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Thiamine metabolism";"Phosphate acquisition";"RNA polymerase II transcribes snRNA genes";"Riboflavin metabolism";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046470166.1	10	Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880	"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases"
XP_046468684.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046489265.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046474212.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046484154.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046490128.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046465561.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_046464993.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046474549.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046480324.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046466434.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046481723.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_046488225.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046487277.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046489522.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_046490699.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046488742.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_046473922.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046491768.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046465598.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_046492655.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046471369.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_046476318.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046478431.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046479103.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046478853.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_046480472.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_046478266.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_046475438.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046477007.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046474995.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046475561.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046470732.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_046489124.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046478204.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_046489687.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation"
XP_046480561.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046490945.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046474972.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046489613.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_046469438.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046482836.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_046476554.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046471749.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046469034.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046471002.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_046490340.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046471343.1	31	MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-6799;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-7858;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-7723;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973	"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"Pederin biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis"
XP_046469240.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359	"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Glucagon signaling in metabolic regulation"
XP_046483340.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046492174.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046485075.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046479064.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046468572.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_046472899.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046481971.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046469500.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046486358.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_046476980.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046484952.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046478830.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_046478300.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046476088.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046486544.1	26	Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-400253;Reactome: R-HSA-1912408	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"FOXO-mediated transcription of cell death genes";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Circadian Clock";"Pre-NOTCH Transcription and Translation"
XP_046479216.1	9	MetaCyc: PWY-7902;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118	"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle"
XP_046466036.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7589	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_046487297.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046489551.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046465255.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046468497.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046466939.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046480742.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046482497.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046477048.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046467224.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046477949.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046481586.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046486003.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046485807.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046482381.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046491600.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046477221.1	13	MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation III (Serratia)"
XP_046475917.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_046467979.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046469296.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046469540.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046473427.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046483195.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_046476341.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_046467098.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046483739.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046479952.1	12	KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599	"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Glycerolipid metabolism";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate"
XP_046491638.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046467395.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046489862.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046491513.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046464862.1	58	Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5689901;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-349425	"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Metalloprotease DUBs";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_046478990.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_046466688.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046487965.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046476315.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046470239.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046484810.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046493182.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046491447.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_046490817.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046467377.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_046488944.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_046486975.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046470464.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046484801.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046489971.1	22	Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046486193.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046469109.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046469242.1	11	Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418555	"Glucagon signaling in metabolic regulation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events"
XP_046469451.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_046472929.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Interleukin-7 signaling";"RMTs methylate histone arginines"
XP_046472022.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046479166.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_046472881.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046486876.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046477616.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046483291.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_046479493.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-389357	"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling"
XP_046479355.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046484907.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046476870.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046470140.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046483885.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046473238.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046468924.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046483969.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046469332.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046484205.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046473720.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_046471968.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046485321.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046466575.1	13	Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-419037	"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Collagen chain trimerization";"Laminin interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"NCAM1 interactions"
XP_046476913.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046473249.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046473252.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046489517.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_046469368.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046481058.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046473862.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046473184.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046480206.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046490193.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046467961.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046478010.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046465037.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_046483252.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_046491772.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046490358.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_046491831.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046490165.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046481824.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046470912.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046472682.1	13	MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_046478082.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)"
XP_046482018.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046472031.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046465589.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_046483848.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_046477675.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046476345.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046482152.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046479957.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046487860.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046474920.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046490900.1	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046472044.1	10	MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I"
XP_046489648.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046491139.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046477999.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046489755.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046478785.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046482441.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"DNA methylation";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism"
XP_046467222.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046485664.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_046484844.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046483518.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046475313.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046472828.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046465996.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_046491467.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_046478812.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_046481185.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001	"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_046479555.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046475857.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046487430.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_046493073.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_046492982.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_046466578.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_046488870.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046468270.1	7	KEGG: 00030+3.1.1.31;MetaCyc: PWY-6906;MetaCyc: PWY-8004;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-71336;MetaCyc: PWY-5514	"Pentose phosphate pathway";"Chitin derivatives degradation";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_046471597.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046480430.1	4	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-379716;Reactome: R-HSA-2408557	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis"
XP_046484904.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046466425.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046483478.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046483942.1	4	MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism"
XP_046473716.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046482131.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046473285.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_046486768.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046485290.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046478741.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046487825.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046493350.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046474866.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046479469.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046486212.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046489105.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_046471314.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046474619.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_046478717.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046491273.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_046481623.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046483520.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046477153.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046469233.1	11	Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418555	"Glucagon signaling in metabolic regulation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events"
XP_046474190.1	8	MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_046487480.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046492795.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046480213.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046468846.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046471085.1	31	MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-8049;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-7858;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147	"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)"
XP_046488618.1	6	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Th1 and Th2 cell differentiation"
XP_046475825.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046482784.1	18	KEGG: 00400+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Sulfolactate degradation III";"Tyrosine metabolism";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation"
XP_046468026.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046480668.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046487755.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_046485332.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046484879.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046487955.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046481159.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046485238.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046476319.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046492631.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046491993.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046484283.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-167290	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation"
XP_046480689.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046468487.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-4551638	"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins"
XP_046479867.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046487145.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859	"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly"
XP_046477335.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046469773.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046484849.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_046476130.1	17	KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-200425;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5743;Reactome: R-HSA-163765	"Pyruvate metabolism";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Candicidin biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression"
XP_046488250.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046470244.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046482420.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046489141.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046468650.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046467330.1	9	Reactome: R-HSA-110329;Reactome: R-HSA-9630221;Reactome: R-HSA-9608290;Reactome: R-HSA-9608287;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9630222;Reactome: R-HSA-110330	"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing";"Defective MUTYH substrate processing";"Defective MUTYH substrate binding";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_046481659.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046492046.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046490380.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046471244.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046492790.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046480084.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690	"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)"
XP_046472911.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046490722.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_046486763.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046477629.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046469295.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046490691.1	12	KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5108;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1	"Methane metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Pyruvate metabolism";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Propanoate metabolism"
XP_046490937.1	5	Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-209543	"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes"
XP_046491300.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_046479148.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046492723.1	7	Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72662	"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_046473625.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046486221.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046465217.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046488689.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_046491910.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_046470062.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046484786.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046487087.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046487649.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046487004.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046464772.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046476232.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046485596.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046491196.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046483824.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046474136.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_046468188.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046488849.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_046485067.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046489218.1	4	MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_046491770.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_046485994.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046475513.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-6802946	"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Long-term potentiation";"RAF/MAP kinase cascade";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants"
XP_046484883.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046491148.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046486660.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046478917.1	5	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_046467901.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_046474802.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046467851.1	4	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
XP_046480066.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046484532.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046472098.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046489033.1	4	MetaCyc: PWY-7849;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691	"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin I"
XP_046491918.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046489111.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2	"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_046480793.1	7	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210	"Mitochondrial protein import";"Cristae formation";"ATP biosynthesis";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling"
XP_046467307.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_046490042.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046487966.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046483025.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619	"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN"
XP_046490449.1	12	MetaCyc: PWY-5340;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.1.25	"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Purine metabolism";"Selenocompound metabolism";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Purine metabolism";"Selenate reduction";"Monobactam biosynthesis";"Sulfur metabolism"
XP_046467385.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046493176.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046491533.1	7	Reactome: R-HSA-9018676;Reactome: R-HSA-9018681;Reactome: R-HSA-9023661;Reactome: R-HSA-9020265;Reactome: R-HSA-2142691;Reactome: R-HSA-6798695;Reactome: R-HSA-9018896	"Biosynthesis of D-series resolvins";"Biosynthesis of protectins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Neutrophil degranulation";"Biosynthesis of E-series 18(S)-resolvins"
XP_046476692.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_046477673.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046484941.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046487742.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046474216.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_046466641.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046474472.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046477410.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_046469825.1	25	Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-381771;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-6814122	"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"G alpha (q) signalling events";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046482876.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046480308.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046491635.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046489478.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046465999.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046470088.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_046473868.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046468518.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046468258.1	6	MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;Reactome: R-HSA-446199	"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate"
XP_046464810.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046466312.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046485194.1	56	Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-174178	"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_046465275.1	3	KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_046487968.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046478787.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046484971.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046489579.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046486598.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_046469239.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Purine metabolism"
XP_046467250.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046489541.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_046464712.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046480241.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_046488101.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_046487659.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046484688.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046483828.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046469647.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046484838.1	4	MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_046472915.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046484861.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_046466696.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046469697.1	7	KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-6596;MetaCyc: PWY-5695	"Drug metabolism - other enzymes";"Purine metabolism";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation"
XP_046486174.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046467205.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046464786.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046492636.1	4	KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30	"Pentose and glucuronate interconversions";"Glycerol degradation I";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism"
XP_046479872.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046483052.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046487527.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_046467948.1	17	Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046492638.1	4	MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270	"Glycerol degradation I";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate"
XP_046474181.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046488070.1	1	Reactome: R-HSA-5669034	"TNFs bind their physiological receptors"
XP_046480825.1	4	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism"
XP_046479967.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis"
XP_046474971.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046478184.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046491371.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_046485639.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046470752.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046466316.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_046467925.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046480160.1	10	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"HATs acetylate histones";"Ub-specific processing proteases";"PI3K-Akt signaling pathway"
XP_046471585.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046481509.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling"
XP_046474602.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_046478814.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046473889.1	4	MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
XP_046491747.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046481051.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046467601.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6781827	"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_046483823.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046465278.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK"
XP_046481493.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_046479083.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046488201.1	6	Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077;MetaCyc: PWY-6906;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25	"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism"
XP_046471468.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046481147.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046474635.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553	"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs"
XP_046469594.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046490141.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_046471333.1	31	Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-8047;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-163765	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression"
XP_046473411.1	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_046484442.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046471399.1	12	KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-601;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-6309	"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_046467954.1	28	Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-3371511;Reactome: R-HSA-6783310;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135	"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HSF1 activation";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Dual incision in TC-NER"
XP_046480810.1	7	Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-418594;Reactome: R-HSA-140837;Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-381426	"Platelet degranulation";"Post-translational protein phosphorylation";"G alpha (i) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_046475797.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046466240.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_046473962.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046485248.1	18	MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-7409	"Anandamide biosynthesis I";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_046471529.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6804756	"Regulation of PTEN stability and activity";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation"
XP_046481471.1	11	MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-6992;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-7456	"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation"
XP_046471451.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-2173788;Reactome: R-HSA-3769402;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-9634638;Reactome: R-HSA-450520;Reactome: R-HSA-69273	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Downregulation of TGF-beta receptor signaling";"Deactivation of the beta-catenin transactivating complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046475440.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046493325.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_046479625.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046469481.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_046482542.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046477224.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_046491892.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046470675.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046474168.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046483438.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046474867.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046478888.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300	"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy";"SUMOylation of transcription cofactors"
XP_046491465.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046488836.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046493352.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_046479354.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046476828.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046476638.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046476257.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046492201.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046485128.1	4	Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism"
XP_046488472.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046468131.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_046468237.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046485139.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046487565.1	19	Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-3000497	"Chylomicron assembly";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"LDL remodeling";"Post-translational protein phosphorylation";"LDL clearance";"Scavenging by Class A Receptors";"VLDL clearance";"Clathrin-mediated endocytosis";"VLDL assembly";"Retinoid metabolism and transport";"Scavenging by Class H Receptors"
XP_046468699.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046493356.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046488284.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046480251.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046482858.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_046477296.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046481032.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046485125.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_046493414.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046470437.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_046488997.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_046475531.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_046472131.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_046486499.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_046476939.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_046486405.1	6	Reactome: R-HSA-3656225;Reactome: R-HSA-3656244;Reactome: R-HSA-3656243;Reactome: R-HSA-2022857;Reactome: R-HSA-3000178;Reactome: R-HSA-2022854	"Defective CHST6 causes MCDC1";"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)";"Defective ST3GAL3 causes MCT12 and EIEE15";"Keratan sulfate degradation";"ECM proteoglycans";"Keratan sulfate biosynthesis"
XP_046486645.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_046464780.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046487386.1	5	KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22	"Glycerolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism"
XP_046466932.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046476799.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4	"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_046484013.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046465226.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046486287.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046468498.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046473774.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis"
XP_046486754.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046475645.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046465717.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046485145.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046464876.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046478929.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_046465719.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046466293.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046487962.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046470158.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046487200.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046464787.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046469177.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_046483039.1	13	MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-7736;MetaCyc: PWY-6383	"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_046484943.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046464936.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046491146.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046488914.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046482170.1	13	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-389357	"Macroautophagy";"Regulation of PTEN gene transcription";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling"
XP_046483475.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_046464815.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_046493194.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-167590	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation"
XP_046467820.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046467665.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_046478818.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_046468640.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046488435.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_046488127.1	7	KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-6596;MetaCyc: PWY-5695	"Drug metabolism - other enzymes";"Purine metabolism";"Neutrophil degranulation";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation"
XP_046480336.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046482873.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046490477.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_046485572.1	7	MetaCyc: PWY-5686;KEGG: 00230+3.5.2.5;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;MetaCyc: PWY-5697;MetaCyc: PWY-5698	"UMP biosynthesis I";"Purine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"Allantoin degradation to ureidoglycolate I (urea producing)";"Allantoin degradation to ureidoglycolate II (ammonia producing)"
XP_046489061.1	5	Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;MetaCyc: PWY-5523;MetaCyc: PWY-6168	"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)"
XP_046475579.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046466819.1	4	KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801	"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion"
XP_046471205.1	10	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72731;Reactome: R-HSA-381042;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-9648895	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Recycling of eIF2:GDP";"PERK regulates gene expression";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046485590.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046479755.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046466679.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
XP_046486151.1	29	Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_046484143.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046473857.1	8	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Macroautophagy"
XP_046472283.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046492000.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_046472643.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046477455.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_046476504.1	19	Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-525793;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-418885	"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"G beta:gamma signalling through CDC42";"EGFR downregulation";"MAPK6/MAPK4 signaling";"Myogenesis";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling"
XP_046476289.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046465524.1	4	KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261	"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_046488874.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046477359.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046465072.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046473350.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_046477345.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046487611.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837	"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation"
XP_046470467.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046470566.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046473370.1	7	MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10	"UMP biosynthesis III";"Drug metabolism - other enzymes";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Pyrimidine metabolism"
XP_046465222.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046489068.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_046477461.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046489975.1	22	Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5467348	"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex"
XP_046476197.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046466617.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046465770.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046489205.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046476321.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046486401.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046491809.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046479047.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_046493131.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046472188.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_046479119.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046475409.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046486057.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046480362.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046486362.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_046482851.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046474724.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046471754.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046476643.1	5	Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9633012	"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046468306.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046485931.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046469911.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_046466318.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_046486451.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_046468685.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046476089.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_046466214.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174048	"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_046483339.1	5	Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16	"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation"
XP_046487044.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046466938.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046486646.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_046477837.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy"
XP_046477470.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046490192.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046472382.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046480834.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046481750.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046466261.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-983168	"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046485663.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046467178.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046490181.1	52	Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-73863;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-1834949;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-76061;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-6807505	"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Cytosolic sensors of pathogen-associated DNA";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
XP_046471301.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046489640.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046493119.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046469760.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046492786.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase"
XP_046482043.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046483851.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046491439.1	6	Reactome: R-HSA-5609978;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12	"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism"
XP_046474200.1	29	Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04151+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-349425;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-6804757;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6803204;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-69541;Reactome: R-HSA-2559586;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693565;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648	"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"G2/M DNA damage checkpoint";"PI3K-Akt signaling pathway";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Degradation";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53";"DNA Damage/Telomere Stress Induced Senescence";"Human cytomegalovirus infection";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"mTOR signaling pathway";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046467475.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046489600.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046484443.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046473462.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046492721.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046468567.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_046469155.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046490014.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046466372.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_046481998.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046464720.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046491087.1	15	MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40	"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis"
XP_046492179.1	4	MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_046474496.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046489791.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046474642.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046489036.1	4	MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7394;MetaCyc: PWY-7849	"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin III"
XP_046491520.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046474851.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_046465194.1	4	Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_046473784.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-977225	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation"
XP_046465836.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_046482952.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_046488264.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046478536.1	17	MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-5695;MetaCyc: PWY-4202;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-5532	"Adenine and adenosine salvage V";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Guanine and guanosine salvage";"Purine metabolism";"Purine catabolism";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Nucleoside and nucleotide degradation (archaea)"
XP_046473617.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_046484441.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046484304.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046469067.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046483794.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046488876.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046478286.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046481884.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046472430.1	17	Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-174437	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand"
XP_046477647.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_046492133.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_046472875.1	14	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC"
XP_046488951.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046476802.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046481347.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046483856.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046470391.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046475387.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046490559.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_046475799.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046481535.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046472418.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783	"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome"
XP_046467095.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046478678.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530	"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II"
XP_046484613.1	4	Reactome: R-HSA-6807062;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026	"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)"
XP_046485079.1	11	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"p38MAPK events";"Human cytomegalovirus infection";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway"
XP_046476102.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046489307.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046467180.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_046472228.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046478299.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046482938.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046473803.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046468919.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046479993.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046474215.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046490907.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046490909.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046489696.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046473945.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046483924.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_046465477.1	14	Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052	"Synthesis of PC";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis"
XP_046487262.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046490026.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046466239.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_046468496.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046466576.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046464894.1	4	MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046479149.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046479118.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046489879.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_046464774.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046481043.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046471074.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189	"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Gap junction assembly";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046472332.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046481006.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046472963.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046482823.1	9	Reactome: R-HSA-8856828;Reactome: R-HSA-9613829;Reactome: R-HSA-5627083;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-9615710;Reactome: R-HSA-8856825;Reactome: R-HSA-9646399	"Clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"RHO GTPases regulate CFTR trafficking";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Late endosomal microautophagy";"Cargo recognition for clathrin-mediated endocytosis";"Aggrephagy"
XP_046466691.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_046464820.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046481477.1	11	MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-7586;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-3861;MetaCyc: PWY-7456	"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Beta-(1,4)-mannan degradation"
XP_046474469.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046492217.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046469154.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046484776.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_046483148.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046486091.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition"
XP_046491840.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046491068.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_046478894.1	33	Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-191859	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"snRNP Assembly"
XP_046488674.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3232118	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of transcription factors"
XP_046486402.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046475765.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_046484978.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046471295.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046466693.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_046480126.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046476135.1	17	Reactome: R-HSA-163765;MetaCyc: PWY-5743;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-200425;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2	"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Carnitine metabolism";"Candicidin biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"Pyruvate metabolism"
XP_046474035.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046486873.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046470484.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046476865.1	24	Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025	"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Cilium Assembly";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation"
XP_046492720.1	7	Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72662	"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_046485818.1	15	Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-8853659;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-912631;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-416476;Reactome: R-HSA-389357;Reactome: R-HSA-114604	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"RET signaling";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"Regulation of signaling by CBL";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"G alpha (q) signalling events";"CD28 dependent PI3K/Akt signaling";"GPVI-mediated activation cascade"
XP_046466772.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046478433.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046473362.1	7	KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10	"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_046488823.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046492234.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_046467232.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046488741.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation"
XP_046479986.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046491805.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046479164.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046464911.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046466923.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046470913.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046474789.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-983231	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production"
XP_046486719.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046491481.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_046492230.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_046473811.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619	"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN"
XP_046473815.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619	"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN"
XP_046471615.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046488394.1	6	Reactome: R-HSA-1660517;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.64	"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_046471461.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_046475114.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046491994.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046488226.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_046487198.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046479458.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046472359.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046478473.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216	"Collagen degradation";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Collagen chain trimerization"
XP_046472931.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling"
XP_046484401.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664	"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Neddylation"
XP_046467991.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046487185.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046489009.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046474804.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046493034.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046466785.1	12	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"DCC mediated attractive signaling";"mTOR signaling pathway"
XP_046470655.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-975634	"Chylomicron clearance";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Chylomicron assembly";"LDL remodeling";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Clathrin-mediated endocytosis";"VLDL clearance";"LDL clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Retinoid metabolism and transport"
XP_046475208.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046489487.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_046470227.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046474889.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_046481922.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046465040.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_046485153.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_046487523.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_046476545.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046470641.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_046480740.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695	"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046481591.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_046480703.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_046477100.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046476524.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046477510.1	10	Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-8936459	"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046466612.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046480738.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046464880.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_046481215.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046465513.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_046492793.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046490635.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046491761.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_046492664.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046487429.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_046476509.1	19	Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-525793;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-182971;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220;Reactome: R-HSA-5625970	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"Myogenesis";"Rho GTPase cycle";"GPVI-mediated activation cascade";"EGFR downregulation";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins";"RHO GTPases activate KTN1"
XP_046480691.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046477155.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046467482.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-428890	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling"
XP_046470709.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046473832.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_046481429.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046478918.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_046471876.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046483966.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046481999.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046479114.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046470776.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046486869.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046486878.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046481141.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-8854518;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"RHO GTPases Activate Formins";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_046476290.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_046475948.1	57	Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5668541	"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway"
XP_046477328.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046475008.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046485223.1	18	Reactome: R-HSA-1482922;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788	"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC"
XP_046486002.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046470940.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-114608	"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation"
XP_046484793.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046490125.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046472330.1	179	Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-209543;Reactome: R-HSA-5676590;Reactome: R-HSA-1169408;Reactome: R-HSA-937072;Reactome: R-HSA-2467813;Reactome: R-HSA-2122948;Reactome: R-HSA-8948747;Reactome: R-HSA-5696395;Reactome: R-HSA-174184;Reactome: R-HSA-936440;Reactome: R-HSA-201681;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-5696394;Reactome: R-HSA-5357956;Reactome: R-HSA-5654727;Reactome: R-HSA-2644606;Reactome: R-HSA-450408;Reactome: R-HSA-6783310;Reactome: R-HSA-5610785;Reactome: R-HSA-9615710;Reactome: R-HSA-6781823;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-9636383;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-6807004;Reactome: R-HSA-975957;Reactome: R-HSA-5656169;Reactome: R-HSA-8939902;Reactome: R-HSA-917729;Reactome: R-HSA-9633012;Reactome: R-HSA-5654726;Reactome: R-HSA-187577;Reactome: R-HSA-175474;Reactome: R-HSA-110320;Reactome: R-HSA-1799339;Reactome: R-HSA-349425;Reactome: R-HSA-5696397;Reactome: R-HSA-975163;Reactome: R-HSA-6781827;Reactome: R-HSA-532668;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-5654732;Reactome: R-HSA-5689603;Reactome: R-HSA-2173796;Reactome: R-HSA-162588;Reactome: R-HSA-5656121;Reactome: R-HSA-211733;Reactome: R-HSA-6782135;Reactome: R-HSA-9020702;Reactome: R-HSA-72689;Reactome: R-HSA-174490;Reactome: R-HSA-182971;Reactome: R-HSA-2173791;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-975956;Reactome: R-HSA-5689901;Reactome: R-HSA-5358346;Reactome: R-HSA-937042;Reactome: R-HSA-917937;Reactome: R-HSA-2559580;Reactome: R-HSA-69231;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-912631;Reactome: R-HSA-174154;Reactome: R-HSA-209560;Reactome: R-HSA-69017;Reactome: R-HSA-2173788;Reactome: R-HSA-5685942;Reactome: R-HSA-180534;Reactome: R-HSA-8856825;Reactome: R-HSA-5610780;Reactome: R-HSA-156902;Reactome: R-HSA-8854050;Reactome: R-HSA-6804756;Reactome: R-HSA-69541;Reactome: R-HSA-5205685;Reactome: R-HSA-5610783;Reactome: R-HSA-168927;Reactome: R-HSA-8876493;Reactome: R-HSA-6791226;Reactome: R-HSA-937039;Reactome: R-HSA-2173795;Reactome: R-HSA-179409;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-3785653;Reactome: R-HSA-1169091;Reactome: R-HSA-3769402;Reactome: R-HSA-2979096;Reactome: R-HSA-9646399;Reactome: R-HSA-168638;Reactome: R-HSA-192823;Reactome: R-HSA-2691232;Reactome: R-HSA-8866654;Reactome: R-HSA-69601;Reactome: R-HSA-5655862;Reactome: R-HSA-2122947;Reactome: R-HSA-69481;Reactome: R-HSA-3134975;Reactome: R-HSA-5675221;Reactome: R-HSA-156827;Reactome: R-HSA-937041;Reactome: R-HSA-9033241;Reactome: R-HSA-110312;Reactome: R-HSA-975144;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-168928;Reactome: R-HSA-1234176;Reactome: R-HSA-450321;Reactome: R-HSA-195253;Reactome: R-HSA-6782210;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-202424;Reactome: R-HSA-1358803;Reactome: R-HSA-174084;Reactome: R-HSA-9013973;Reactome: R-HSA-901032;Reactome: R-HSA-2559585;Reactome: R-HSA-9010553;Reactome: R-HSA-2672351;Reactome: R-HSA-4641263;Reactome: R-HSA-5357905;Reactome: R-HSA-3322077;Reactome: R-HSA-6804757;Reactome: R-HSA-1295596;Reactome: R-HSA-5689877;Reactome: R-HSA-5689896;Reactome: R-HSA-5607761;Reactome: R-HSA-1253288;Reactome: R-HSA-2565942;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-5675482;Reactome: R-HSA-1236974;Reactome: R-HSA-9613829;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-9013507;Reactome: R-HSA-8939236;Reactome: R-HSA-8866652;Reactome: R-HSA-975110;Reactome: R-HSA-68827;Reactome: R-HSA-2559582;Reactome: R-HSA-8863795;Reactome: R-HSA-2408557;Reactome: R-HSA-9645460;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-936964;Reactome: R-HSA-8951664;Reactome: R-HSA-5693607;Reactome: R-HSA-8875360;Reactome: R-HSA-8849469;Reactome: R-HSA-9637628;Reactome: R-HSA-6804760;Reactome: R-HSA-8856828;Reactome: R-HSA-5693565;Reactome: R-HSA-8948751;Reactome: R-HSA-1236382;Reactome: R-HSA-5654733;Reactome: R-HSA-205043;Reactome: R-HSA-2871837	"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"p75NTR recruits signalling complexes";"NIK-->noncanonical NF-kB signaling";"ISG15 antiviral mechanism";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Separation of Sister Chromatids";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of PTEN localization";"Formation of Incision Complex in GG-NER";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulators of DDX58/IFIH1 signaling";"TCF dependent signaling in response to WNT";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"DNA Damage Recognition in GG-NER";"TNFR1-induced NFkappaB signaling pathway";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Fanconi Anemia Pathway";"GLI3 is processed to GLI3R by the proteasome";"Late endosomal microautophagy";"Formation of TC-NER Pre-Incision Complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Prevention of phagosomal-lysosomal fusion";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"Negative regulation of MET activity";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Termination of translesion DNA synthesis";"Regulation of RUNX2 expression and activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Negative regulation of FGFR1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Assembly Of The HIV Virion";"Translesion Synthesis by POLH";"SRP-dependent cotranslational protein targeting to membrane";"Autodegradation of the E3 ubiquitin ligase COP1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Negative regulation of FGFR3 signaling";"UCH proteinases";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Budding and maturation of HIV virion";"Translesion synthesis by POLI";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dual incision in TC-NER";"Interleukin-1 signaling";"Formation of a pool of free 40S subunits";"Membrane binding and targetting of GAG proteins";"EGFR downregulation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Metalloprotease DUBs";"Hedgehog ligand biogenesis";"IRAK2 mediated activation of TAK1 complex";"Iron uptake and transport";"Oxidative Stress Induced Senescence";"Cyclin D associated events in G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Regulation of signaling by CBL";"APC/C:Cdc20 mediated degradation of Securin";"NF-kB is activated and signals survival";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of TGF-beta receptor signaling";"HDR through Homologous Recombination (HRR)";"Vpu mediated degradation of CD4";"Cargo recognition for clathrin-mediated endocytosis";"Degradation of GLI1 by the proteasome";"Peptide chain elongation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53";"Pink/Parkin Mediated Mitophagy";"Degradation of GLI2 by the proteasome";"TICAM1, RIP1-mediated IKK complex recruitment";"InlA-mediated entry of Listeria monocytogenes into host cells";"Major pathway of rRNA processing in the nucleolus and cytosol";"IRAK1 recruits IKK complex";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"APC-Cdc20 mediated degradation of Nek2A";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Myoclonic epilepsy of Lafora";"Activation of NF-kappaB in B cells";"Deactivation of the beta-catenin transactivating complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Aggrephagy";"NOD1/2 Signaling Pathway";"Viral mRNA Translation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Translesion synthesis by POLK";"NOTCH1 Intracellular Domain Regulates Transcription";"G2/M Checkpoints";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of MAPK pathway";"L13a-mediated translational silencing of Ceruloplasmin expression";"IKK complex recruitment mediated by RIP1";"Peroxisomal protein import";"Translesion synthesis by REV1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Degradation of beta-catenin by the destruction complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"Downstream TCR signaling";"Downregulation of ERBB2:ERBB3 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TICAM1-dependent activation of IRF3/IRF7";"ER Quality Control Compartment (ERQC)";"Oncogene Induced Senescence";"Regulation of expression of SLITs and ROBOs";"Stimuli-sensing channels";"Regulation of FZD by ubiquitination";"Regulation of TNFR1 signaling";"Glycogen synthesis";"Regulation of TP53 Degradation";"Spry regulation of FGF signaling";"Josephin domain DUBs";"Ovarian tumor domain proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"Downregulation of ERBB4 signaling";"Regulation of PLK1 Activity at G2/M Transition";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Regulation of necroptotic cell death";"ER-Phagosome pathway";"Chaperone Mediated Autophagy";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Senescence-Associated Secretory Phenotype (SASP)";"Downregulation of ERBB2 signaling";"Selenocysteine synthesis";"Alpha-protein kinase 1 signaling pathway";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Neddylation";"Processing of DNA double-strand break ends";"InlB-mediated entry of Listeria monocytogenes into host cell";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Modulation by Mtb of host immune system";"Regulation of TP53 Activity through Methylation";"Clathrin-mediated endocytosis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of PTEN stability and activity";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of FGFR4 signaling";"NRIF signals cell death from the nucleus";"FCERI mediated NF-kB activation"
XP_046476261.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025	"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation"
XP_046491701.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046493012.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046468174.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046482052.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168276	"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways"
XP_046487383.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_046466856.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046469128.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism"
XP_046479474.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046476633.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046476075.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_046491095.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046477990.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046477614.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046486459.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046487677.1	7	Reactome: R-HSA-1660499;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;MetaCyc: PWY-6351	"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_046464726.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046492794.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046482289.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_046481645.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046469283.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046475439.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046473248.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046469299.1	5	Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110381	"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_046490379.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569	"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046467476.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046483840.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046480816.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-165159	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"Neutrophil degranulation";"mTOR signalling"
XP_046483734.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046469328.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046478105.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046464727.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046466420.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046470242.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046480210.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046485417.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167152	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_046482826.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-9646399;Reactome: R-HSA-8856825	"RHO GTPases regulate CFTR trafficking";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Late endosomal microautophagy";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis"
XP_046469127.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification"
XP_046477133.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_046467811.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046467900.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046484278.1	15	Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-176034;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167290	"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation"
XP_046481445.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046490123.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046467676.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258	"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Degradation of DVL"
XP_046481977.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_046473118.1	4	MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046476154.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_046477227.1	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_046484232.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046486533.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046490686.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_046482134.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046492218.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046476646.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046486160.1	5	MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_046473592.1	10	MetaCyc: PWY-7344;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-5609977	"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"Galactose metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_046479859.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046489360.1	3	Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985	"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose"
XP_046487625.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046474809.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046488834.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046468300.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046472133.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046464732.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046493327.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046470889.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046468662.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046474179.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046479651.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_046492731.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation"
XP_046476730.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046486635.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_046484089.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243	"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046476941.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046474841.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046492651.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046474983.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046477904.1	9	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535;Reactome: R-HSA-2173788;Reactome: R-HSA-3642279;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3645790	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR2 MSI Frameshift Mutants in Cancer";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGFBR2 Kinase Domain Mutants in Cancer"
XP_046479297.1	7	MetaCyc: PWY-5941;MetaCyc: PWY-7238;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6737	"Glycogen degradation II";"Sucrose biosynthesis II";"Starch degradation II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V"
XP_046468364.1	13	MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4061;Reactome: R-HSA-196836	"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Drug metabolism - other enzymes";"Ascorbate glutathione cycle";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism"
XP_046471478.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046482397.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046472886.1	14	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC"
XP_046480580.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_046486164.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046466356.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_046487657.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046467474.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046486288.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)"
XP_046475209.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046473321.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046469790.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_046484237.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046486050.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046471666.1	7	Reactome: R-HSA-4641258;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-5368598	"Degradation of DVL";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins"
XP_046478518.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046474520.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_046488017.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046484841.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_046487427.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_046477506.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046479123.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046467026.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046489153.1	8	KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism"
XP_046484951.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046470060.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757	"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation"
XP_046470552.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046488564.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_046466724.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_046481760.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046490361.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_046483386.1	5	KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891	"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)"
XP_046472346.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046484831.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569	"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046475960.1	16	Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-1227986;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-1251985;Reactome: R-HSA-8863795	"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"Nuclear signaling by ERBB4";"Downregulation of ERBB2 signaling"
XP_046492353.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046489664.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046470469.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_046484800.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046472442.1	32	Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-113418	"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex"
XP_046466133.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046491992.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046471523.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046488420.1	8	KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;MetaCyc: PWY-7193;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_046476133.1	17	Reactome: R-HSA-200425;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-196780	"Carnitine metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Jadomycin biosynthesis";"Pyruvate metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Biotin transport and metabolism"
XP_046492890.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_046484715.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046477726.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_046488675.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046478302.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046480687.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046470076.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046470075.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046474432.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046491746.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046471199.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_046487205.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_046476340.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_046468631.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046482044.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858	"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines"
XP_046490038.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046471573.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046484716.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046478730.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046469022.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046473585.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046480600.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_046486735.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046480313.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046466181.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046466697.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_046470390.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046489237.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046480665.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240	"Basigin interactions";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism"
XP_046465172.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046470420.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046480368.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046470237.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046482025.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046484827.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692	"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity"
XP_046471998.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046469995.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046470115.1	57	Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695	"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation"
XP_046476942.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046485560.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_046473194.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046468328.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_046484040.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_046482206.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046466197.1	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_046472871.1	14	KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053	"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II"
XP_046484846.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_046470027.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_046471094.1	5	MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7279	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)"
XP_046477725.1	7	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis"
XP_046489288.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046487970.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046478436.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046483062.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046472923.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046492502.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046486122.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046483255.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_046492341.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_046466378.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_046467020.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_046465564.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_046486780.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046468890.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046484833.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8934593	"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity"
XP_046484302.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046484016.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046485996.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046466038.1	14	KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417	"Glycerolipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)"
XP_046492085.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685	"Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy"
XP_046488233.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046483431.1	10	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04660+2.7.10.2	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Regulation of TNFR1 signaling";"Human immunodeficiency virus 1 infection";"TNFR1-induced NFkappaB signaling pathway";"T cell receptor signaling pathway"
XP_046484820.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046485460.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_046468467.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046482968.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_046492834.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046470526.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046474710.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046469464.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046484535.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046477277.1	12	MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism"
XP_046474517.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_046469241.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events"
XP_046476645.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046482009.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_046469671.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046469294.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046479662.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_046468987.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_046490816.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane"
XP_046473950.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046469749.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_046469018.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046465052.1	7	MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-6596	"Inosine 5'-phosphate degradation";"Purine metabolism";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I"
XP_046489504.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_046469074.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046479099.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046491432.1	6	KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-5609978	"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia"
XP_046487568.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_046474990.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7117	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_046472440.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_046466037.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51	"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism"
XP_046482003.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046466658.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046486803.1	5	MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-7766;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis"
XP_046469062.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046492985.1	14	KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-6969	"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_046467203.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046484874.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-7456	"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation"
XP_046469287.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_046478934.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_046485105.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046472791.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_046480359.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046483521.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046486574.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046486748.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046477177.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046479097.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046483057.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046479488.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046490517.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046491795.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046481668.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046477131.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046466180.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046478822.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046481543.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901	"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Metalloprotease DUBs"
XP_046470412.1	3	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_046465775.1	6	KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6908;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-6898	"Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III"
XP_046473239.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046471309.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046474024.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_046475816.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_046478274.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_046489509.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_046483306.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046464714.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046488607.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046469271.1	4	Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism"
XP_046465135.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046476423.1	8	MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_046467667.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046490920.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046489138.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046480587.1	22	MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6958;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7726;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-8041	"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
XP_046476334.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046480515.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046479455.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046482144.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046472947.1	4	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
XP_046467545.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046482539.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046476387.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046469279.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046478271.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046466651.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_046491456.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_046477729.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046477061.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046490343.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046481200.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046473429.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046489705.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046468269.1	17	Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-5696397	"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_046474784.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046480520.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046465534.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046481427.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046478617.1	15	Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-111465	"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins"
XP_046467229.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046471232.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046476919.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046487967.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046470972.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046472119.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_046480539.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046488685.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events"
XP_046491111.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046480501.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_046489598.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046488896.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046486289.1	13	MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822	"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation III (Serratia)"
XP_046472625.1	30	Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-2644607;Reactome: R-HSA-1170546;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-2644606;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-5610780;Reactome: R-HSA-2894862;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-400253;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-917937;Reactome: R-HSA-69231;Reactome: R-HSA-2871837	"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Prolactin receptor signaling";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Circadian Clock";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Iron uptake and transport";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation"
XP_046475251.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_046469066.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046475374.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046477135.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046465185.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046485655.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046467221.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046474647.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_046488667.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046492565.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation"
XP_046476921.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046492125.1	6	MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-6983	"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis"
XP_046479456.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Neutrophil degranulation"
XP_046471567.1	11	MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-5695;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-6999;Reactome: R-HSA-74259	"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine metabolism";"Adenosine nucleotides degradation I";"Theophylline degradation";"Purine catabolism"
XP_046466643.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046479972.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_046479414.1	11	KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_046469237.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040	"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_046484364.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046484325.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046471038.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046488197.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046479163.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046487637.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046479912.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046493383.1	10	Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-611105	"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport"
XP_046475472.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-111932	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"RAF activation";"Long-term potentiation";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB"
XP_046482972.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046468673.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_046486657.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_046488922.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046477719.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_046474518.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_046475530.1	7	Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_046474868.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046486219.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046486965.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_046480966.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_046486866.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046483504.1	5	KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7536;MetaCyc: PWY-5189	"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046483283.1	16	Reactome: R-HSA-1810476;Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-5602680;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-209543;Reactome: R-HSA-975155;Reactome: R-HSA-975871;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-3134963;Reactome: R-HSA-5603037;Reactome: R-HSA-975138;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702	"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"p75NTR recruits signalling complexes";"MyD88 dependent cascade initiated on endosome";"MyD88 cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"ER-Phagosome pathway";"Interleukin-1 signaling"
XP_046473597.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046475471.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_046487385.1	5	KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism"
XP_046476654.1	5	Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4	"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism"
XP_046478124.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046472055.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)"
XP_046481778.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046481201.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-389661	"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation"
XP_046487643.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046490687.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_046477230.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_046470731.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_046484680.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046493192.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_046476320.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046485173.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046489704.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_046468663.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046464773.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046469460.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046483583.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046473813.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941	"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses"
XP_046475301.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046474726.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046468994.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046478538.1	17	Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-4202;MetaCyc: PWY-5695;MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-6627	"Neutrophil degranulation";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Purine catabolism";"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis"
XP_046467788.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046467296.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046464733.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046469993.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046474641.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046479316.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046485222.1	18	MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417	"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_046468983.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046465901.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046468018.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046475957.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046465053.1	7	MetaCyc: PWY-6596;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-5695	"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Neutrophil degranulation";"Inosine 5'-phosphate degradation"
XP_046476060.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046487424.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046475747.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046476473.1	3	Reactome: R-HSA-5666185;MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60	"RHO GTPases Activate Rhotekin and Rhophilins";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis"
XP_046480380.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_046492394.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555	"ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation"
XP_046492491.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046476803.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046480028.1	52	Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128	"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of DVL";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling"
XP_046484940.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046469258.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis"
XP_046478635.1	7	MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_046486537.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046486512.1	7	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_046492673.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046466770.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046490821.1	52	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-749476;Reactome: R-HSA-167246;Reactome: R-HSA-76071;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-73780;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-6803529;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-5601884	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Chain Elongation";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis"
XP_046467420.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046479093.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046490305.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046466317.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_046470328.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046473463.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046483958.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
XP_046468689.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_046485138.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046482007.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_046467926.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046480082.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046476655.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046471316.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046486375.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046484736.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046480404.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046488604.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046479170.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046481959.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046477915.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046479120.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046479563.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_046465391.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046472840.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046473247.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046473626.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046491172.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5632927	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH3"
XP_046491312.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046479008.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046484144.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046485847.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046485296.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046487636.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046484998.1	3	Reactome: R-HSA-166663;Reactome: R-HSA-977606;Reactome: R-HSA-173623	"Initial triggering of complement";"Regulation of Complement cascade";"Classical antibody-mediated complement activation"
XP_046488402.1	8	KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;MetaCyc: PWY-7193;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_046478645.1	7	MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5466	"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis"
XP_046467959.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes"
XP_046482427.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046485567.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_046483146.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046475835.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046476933.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_046492666.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046469850.1	7	MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_046475191.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046485597.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046470845.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542	"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation"
XP_046476958.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046466506.1	17	Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-5357956;Reactome: R-HSA-1169091;Reactome: R-HSA-975163;Reactome: R-HSA-5689880;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-450321	"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046485971.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046490144.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046491820.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046481350.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23	"Neutrophil degranulation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series"
XP_046469672.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046491081.1	15	Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-1042	"Glycolysis";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)"
XP_046482280.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046491633.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046476090.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_046474728.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046484207.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046488346.1	5	Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-201722	"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex"
XP_046480707.1	5	KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20	"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate transformations I";"One carbon pool by folate"
XP_046474237.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_046473714.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046478428.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046472240.1	8	Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324	"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046493127.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046474811.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046484021.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046492596.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046491812.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046484737.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046476502.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046493089.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046491112.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046474083.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046488632.1	4	MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;Reactome: R-HSA-189483	"Heme degradation I";"Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation"
XP_046480202.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046478264.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046482540.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046468687.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046475533.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952	"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"RAF activation";"Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions"
XP_046474887.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046469041.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046482682.1	17	Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648	"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046485336.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046489267.1	6	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-8876198;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"RAB GEFs exchange GTP for GDP on RABs";"HCMV Late Events";"Late endosomal microautophagy"
XP_046482974.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046479745.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046467101.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_046482015.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046479299.1	7	Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-7238;MetaCyc: PWY-5941	"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism";"Neutrophil degranulation";"Starch degradation II";"Sucrose biosynthesis II";"Glycogen degradation II"
XP_046490121.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046483121.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046485630.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046492755.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046474349.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_046485811.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_046465844.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046492365.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046492123.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046469255.1	52	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-73762;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-76061;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-5578749;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-113418	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"Transcriptional regulation by small RNAs";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex"
XP_046472302.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_046465332.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_046482544.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046474629.1	16	Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-167290	"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Pausing and recovery of HIV elongation"
XP_046479843.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046478183.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046466848.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_046482176.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046475144.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046478808.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046483256.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_046489052.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046490923.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046467417.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046487621.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046486439.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046488662.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Photosynthesis";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Oxidative phosphorylation"
XP_046492498.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046468883.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046466854.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_046484610.1	4	MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism"
XP_046480694.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_046482878.1	19	Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-8964041	"LDL clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"VLDL assembly";"Clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class H Receptors";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Chylomicron assembly";"Chylomicron remodeling";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling"
XP_046471471.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046480608.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046487976.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_046473903.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046468294.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-4551638	"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins"
XP_046474204.1	29	Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-349425;Reactome: R-HSA-3371453;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-6803204;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-69541;Reactome: R-HSA-2559586;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-6803207;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648	"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53";"DNA Damage/Telomere Stress Induced Senescence";"Human cytomegalovirus infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of Caspase Activators and Caspases";"mTOR signaling pathway";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046475881.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_046468629.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046475808.1	11	Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-202733	"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Syndecan interactions";"HS-GAG degradation";"Cell surface interactions at the vascular wall"
XP_046472069.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174084	"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_046481881.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_046485805.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046473701.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046476396.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046487197.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046487088.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046480790.1	6	Reactome: R-HSA-749476;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046474201.1	29	Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-6803204;Reactome: R-HSA-6804756;Reactome: R-HSA-69541;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-5693568;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-912446;Reactome: R-HSA-349425;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-6804757;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Human cytomegalovirus infection";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Degradation";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks"
XP_046470751.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046483502.1	5	KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-7536	"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_046492314.1	5	Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-901032;Reactome: R-HSA-381038;MetaCyc: PWY-7511	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Protein ubiquitination"
XP_046473115.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041	"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_046477513.1	10	Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-9022692	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity"
XP_046469413.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_046487435.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_046470673.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046473558.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756	"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation"
XP_046482568.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046483030.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046474152.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046485883.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046477212.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046483544.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_046489397.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-4551638	"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of chromatin organization proteins"
XP_046485848.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046477143.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046477523.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_046466748.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046479723.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046492413.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036	"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
XP_046483631.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046468169.1	19	MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methane metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism"
XP_046468295.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046472831.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046484065.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes"
XP_046476177.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046479122.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046483755.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046465720.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046480701.1	3	KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
XP_046480849.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_046465537.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046481512.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"Purine metabolism";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_046479987.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046483719.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_046485064.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046491824.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046486800.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046488223.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046488069.1	1	Reactome: R-HSA-5669034	"TNFs bind their physiological receptors"
XP_046492370.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046477134.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_046470868.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046468327.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046483777.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046474770.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_046474845.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_046472211.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046467292.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046492741.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046486776.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046482205.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046474875.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_046491960.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046491535.1	4	MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210	"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine"
XP_046476137.1	17	Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-196780	"Carnitine metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Jadomycin biosynthesis";"Pyruvate metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Biotin transport and metabolism"
XP_046467630.1	17	Reactome: R-HSA-111448;Reactome: R-HSA-69205;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-9616222;Reactome: R-HSA-1538133;Reactome: R-HSA-2559585;Reactome: R-HSA-113501;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-2559580;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1912408	"Activation of NOXA and translocation to mitochondria";"G1/S-Specific Transcription";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of granulopoiesis";"G0 and Early G1";"Oncogene Induced Senescence";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Pre-NOTCH Transcription and Translation"
XP_046489767.1	6	KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III";"Drug metabolism - other enzymes"
XP_046486370.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046477312.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046482110.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046472341.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046471849.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_046492831.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046492597.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046465771.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046480648.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046484981.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046485337.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046488954.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_046489492.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046480307.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046484380.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_046482822.1	9	Reactome: R-HSA-9646399;Reactome: R-HSA-8856825;Reactome: R-HSA-5627083;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880	"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis";"RHO GTPases regulate CFTR trafficking";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Late endosomal microautophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases"
XP_046488597.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046482795.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_046478747.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046480421.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046474729.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046473342.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046475644.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_046465673.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046491639.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046490390.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046490127.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046489738.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046488927.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046491559.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046487513.1	39	Reactome: R-HSA-109704;Reactome: R-HSA-5654687;Reactome: R-HSA-2033519;Reactome: R-HSA-5654732;Reactome: R-HSA-5658623;Reactome: R-HSA-5654228;Reactome: R-HSA-190375;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-2219530;Reactome: R-HSA-2033514;Reactome: R-HSA-5654704;Reactome: R-HSA-5654689;Reactome: R-HSA-5654695;Reactome: R-HSA-5654219;Reactome: R-HSA-5654221;Reactome: R-HSA-5654719;Reactome: R-HSA-5654720;Reactome: R-HSA-8853338;Reactome: R-HSA-5654727;Reactome: R-HSA-5655302;Reactome: R-HSA-5654227;Reactome: R-HSA-190373;Reactome: R-HSA-190372;Reactome: R-HSA-1839130;Reactome: R-HSA-5654693;Reactome: R-HSA-5654726;Reactome: R-HSA-5673001;Reactome: R-HSA-5654733;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5654688;Reactome: R-HSA-190371;Reactome: R-HSA-5654710;Reactome: R-HSA-5654712;Reactome: R-HSA-5655253;Reactome: R-HSA-1839122;Reactome: R-HSA-5654699;Reactome: R-HSA-190322	"PI3K Cascade";"Downstream signaling of activated FGFR1";"Activated point mutants of FGFR2";"Negative regulation of FGFR3 signaling";"FGFRL1 modulation of FGFR1 signaling";"Phospholipase C-mediated cascade, FGFR4";"FGFR2c ligand binding and activation";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"FGFR3 mutant receptor activation";"SHC-mediated cascade:FGFR3";"PI-3K cascade:FGFR1";"PI-3K cascade:FGFR2";"Phospholipase C-mediated cascade: FGFR1";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR4";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR2 signaling";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade, FGFR3";"FGFR1c ligand binding and activation";"FGFR3c ligand binding and activation";"Signaling by activated point mutants of FGFR3";"FRS-mediated FGFR1 signaling";"Negative regulation of FGFR1 signaling";"RAF/MAP kinase cascade";"Negative regulation of FGFR4 signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC-mediated cascade:FGFR1";"FGFR3b ligand binding and activation";"PI-3K cascade:FGFR3";"FRS-mediated FGFR4 signaling";"Signaling by FGFR2 in disease";"Signaling by activated point mutants of FGFR1";"SHC-mediated cascade:FGFR2";"FGFR4 ligand binding and activation"
XP_046475878.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046483257.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632	"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis"
XP_046468413.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_046475388.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046487512.1	39	Reactome: R-HSA-5654687;Reactome: R-HSA-109704;Reactome: R-HSA-5654732;Reactome: R-HSA-2033519;Reactome: R-HSA-5654228;Reactome: R-HSA-5658623;Reactome: R-HSA-190375;Reactome: R-HSA-2219530;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-2033514;Reactome: R-HSA-5654689;Reactome: R-HSA-5654704;Reactome: R-HSA-5654221;Reactome: R-HSA-5654219;Reactome: R-HSA-5654695;Reactome: R-HSA-5654720;Reactome: R-HSA-5654719;Reactome: R-HSA-190373;Reactome: R-HSA-5654227;Reactome: R-HSA-5655302;Reactome: R-HSA-5654727;Reactome: R-HSA-8853338;Reactome: R-HSA-1839130;Reactome: R-HSA-190372;Reactome: R-HSA-5654733;Reactome: R-HSA-5673001;Reactome: R-HSA-5654726;Reactome: R-HSA-5654693;Reactome: R-HSA-5654688;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-190371;Reactome: R-HSA-5654710;Reactome: R-HSA-1839122;Reactome: R-HSA-5654699;Reactome: R-HSA-190322;Reactome: R-HSA-5655253;Reactome: R-HSA-5654712	"Downstream signaling of activated FGFR1";"PI3K Cascade";"Negative regulation of FGFR3 signaling";"Activated point mutants of FGFR2";"Phospholipase C-mediated cascade, FGFR4";"FGFRL1 modulation of FGFR1 signaling";"FGFR2c ligand binding and activation";"Constitutive Signaling by Aberrant PI3K in Cancer";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"FGFR3 mutant receptor activation";"PI-3K cascade:FGFR1";"SHC-mediated cascade:FGFR3";"Phospholipase C-mediated cascade, FGFR2";"Phospholipase C-mediated cascade: FGFR1";"PI-3K cascade:FGFR2";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR4";"FGFR1c ligand binding and activation";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR1 in disease";"Negative regulation of FGFR2 signaling";"Signaling by FGFR3 point mutants in cancer";"Signaling by activated point mutants of FGFR3";"FGFR3c ligand binding and activation";"Negative regulation of FGFR4 signaling";"RAF/MAP kinase cascade";"Negative regulation of FGFR1 signaling";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR1";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FGFR3b ligand binding and activation";"PI-3K cascade:FGFR3";"Signaling by activated point mutants of FGFR1";"SHC-mediated cascade:FGFR2";"FGFR4 ligand binding and activation";"Signaling by FGFR2 in disease";"FRS-mediated FGFR4 signaling"
XP_046468031.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_046486286.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046477389.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046473632.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_046469097.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN"
XP_046469116.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046482228.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046483880.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046486497.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane"
XP_046468599.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_046488364.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046475112.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046471671.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046492807.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_046478318.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046475325.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046474931.1	23	Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-4086398	"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Ca2+ pathway"
XP_046464719.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046491745.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_046481964.1	4	Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875656	"MET activates RAP1 and RAC1";"Downstream signal transduction";"Regulation of signaling by CBL";"MET receptor recycling"
XP_046487546.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Choline catabolism";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046490387.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046477051.1	4	KEGG: 00010+3.1.3.9;KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Gluconeogenesis"
XP_046490823.1	52	Reactome: R-HSA-72165;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-5578749;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-76071	"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Transcriptional regulation by small RNAs";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046483500.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_046469069.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046467478.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-2029482	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_046471840.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046483953.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_046483436.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046486279.1	13	MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822	"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation III (Serratia)"
XP_046488592.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046468545.1	25	Reactome: R-HSA-8939256;Reactome: R-HSA-8936459;Reactome: R-HSA-8941332;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8941326;Reactome: R-HSA-8939245;Reactome: R-HSA-8939236;Reactome: R-HSA-8949275;Reactome: R-HSA-8939242;Reactome: R-HSA-8939243;Reactome: R-HSA-8940973;Reactome: R-HSA-8939902;Reactome: R-HSA-8951936;Reactome: R-HSA-8878166;Reactome: R-HSA-8941858;Reactome: R-HSA-8939246;Reactome: R-HSA-8931987;Reactome: R-HSA-9616222;Reactome: R-HSA-8934593;Reactome: R-HSA-8941333;Reactome: R-HSA-8935964;Reactome: R-HSA-8941284;Reactome: R-HSA-8951911;Reactome: R-HSA-8939247	"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates genes involved in cell migration";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX2 expression and activity";"RUNX3 regulates p14-ARF";"Transcriptional regulation by RUNX2";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling"
XP_046476149.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046490087.1	4	KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046482141.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046474482.1	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
XP_046470332.1	9	Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER"
XP_046466423.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046482092.1	7	Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
XP_046488203.1	20	Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-8943724;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165159;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-380972	"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"Macroautophagy";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Regulation of PTEN gene transcription";"Human papillomavirus infection";"mTOR signalling";"Thermogenesis";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046483534.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046488541.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-432720	"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis"
XP_046481600.1	10	KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257	"Thermogenesis";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"RSK activation"
XP_046490398.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046486007.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046476532.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046479746.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046490126.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046467552.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046476746.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046478252.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046487971.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046480103.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046474172.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046490406.1	3	KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle"
XP_046478537.1	17	Reactome: R-HSA-6798695;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-74259;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-5695;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6608;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5532	"Neutrophil degranulation";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Guanine and guanosine salvage";"Purine catabolism";"Adenine and adenosine salvage III";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)"
XP_046485878.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-2151201	"HATs acetylate histones";"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis"
XP_046469129.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_046476977.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046469974.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_046477615.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046475319.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046468967.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_046485825.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046473112.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046477718.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046491554.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046473475.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046476325.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_046472834.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046484894.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_046477468.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046474617.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_046478268.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046471668.1	7	Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-5368598;Reactome: R-HSA-4086400;Reactome: R-HSA-5663220;Reactome: R-HSA-201681;Reactome: R-HSA-4641258	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"PCP/CE pathway";"RHO GTPases Activate Formins";"TCF dependent signaling in response to WNT";"Degradation of DVL"
XP_046487615.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046483638.1	9	Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046467551.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046481962.1	12	KEGG: 04714+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046490589.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046483275.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_046490673.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046466371.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_046475524.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination"
XP_046477123.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046466956.1	9	KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_046467060.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046484456.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046472861.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_046471764.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7115	"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_046477758.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046482303.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_046480377.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046492359.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046472770.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046469763.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046492066.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046490474.1	12	Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278	"Transport and synthesis of PAPS";"Purine metabolism";"Selenate reduction";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Purine metabolism";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Sulfite oxidation III"
XP_046478250.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine"
XP_046481831.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046484058.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046470482.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-113501	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_046464725.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046477911.1	9	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535;Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_046472465.1	6	Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose and glucuronate interconversions"
XP_046469061.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046481027.1	5	MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082	"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_046492368.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046467554.1	17	Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409	"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A"
XP_046475429.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-442982	"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"RAF activation";"Long-term potentiation";"Ion transport by P-type ATPases";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_046478260.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046467809.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046489139.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046486703.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046477130.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046480423.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046487522.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_046483522.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046482171.1	13	Reactome: R-HSA-165159;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-389357;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400	"mTOR signalling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_046480669.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046487891.1	11	MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-6453	"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis II";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis"
XP_046489410.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046489674.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046482482.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046491647.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046477065.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046491458.1	40	Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-6782135;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-6781823	"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Dual incision in TC-NER";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex"
XP_046487130.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046465781.1	9	Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-194840	"GPVI-mediated activation cascade";"NRAGE signals death through JNK";"FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle"
XP_046472165.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_046484003.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046480571.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046481842.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_046489871.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046488254.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046476388.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046472876.1	14	MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Retinoid metabolism and transport"
XP_046487699.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046492610.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046477981.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis"
XP_046487199.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046479971.1	8	Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis"
XP_046483022.1	13	Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5689896;Reactome: R-HSA-8866654;Reactome: R-HSA-8876725;Reactome: R-HSA-3371511;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-532668	"Aggrephagy";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Ovarian tumor domain proteases";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation";"HSF1 activation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046482384.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690	"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"HCMV Early Events"
XP_046469313.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046474563.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046474574.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046466542.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046491198.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046473471.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046480096.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046476030.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;MetaCyc: PWY-5381;MetaCyc: PWY-5653	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_046469112.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046467225.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046492363.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046465192.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046468191.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046488771.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046469964.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046486952.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046485621.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046476810.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_046486739.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046468248.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046489014.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046479218.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III"
XP_046488743.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184	"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_046473380.1	7	MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23	"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_046487833.1	24	Reactome: R-HSA-392451;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-2871837;Reactome: R-HSA-444257;Reactome: R-HSA-354192;Reactome: R-HSA-1257604;Reactome: R-HSA-9634635;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;Reactome: R-HSA-5625740	"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Activation of AKT2";"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"FCERI mediated NF-kB activation";"RSK activation";"Integrin signaling";"PIP3 activates AKT signaling";"Estrogen-stimulated signaling through PRKCZ";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"RHO GTPases activate PKNs"
XP_046480316.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046480863.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046481293.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046473031.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
XP_046479618.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046465735.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046470907.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046466314.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046483480.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046471637.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046479640.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046490103.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_046466432.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046491590.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046470970.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046490667.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046472434.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046487109.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046466405.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046467230.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046465114.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046474430.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046482870.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046479828.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_046473887.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
XP_046469033.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046474783.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046465523.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046476563.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046491595.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046484339.1	20	MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_046477429.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046491597.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046487384.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_046477347.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459	"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046482385.1	6	Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569	"HCMV Early Events";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046482452.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation"
XP_046465517.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046492662.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046471112.1	31	MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-7746;MetaCyc: PWY-5147;MetaCyc: PWY-8012;MetaCyc: PWYG-321;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWY-6519;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-5971;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;MetaCyc: PWY-7858;MetaCyc: PWY-5994;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-6799;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7664;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-8049	"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Pederin biosynthesis"
XP_046469854.1	7	KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897	"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes"
XP_046467855.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones"
XP_046482545.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046472141.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046465077.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_046488878.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046481756.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046483644.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046473423.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046469180.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_046476723.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046490670.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046478907.1	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;KEGG: 00020+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_046478244.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046471978.1	6	Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
XP_046488699.1	30	Reactome: R-HSA-69656;Reactome: R-HSA-8941332;Reactome: R-HSA-5628897;Reactome: R-HSA-211163;Reactome: R-HSA-389357;Reactome: R-HSA-198323;Reactome: R-HSA-1358803;Reactome: R-HSA-8876198;KEGG: 05170+2.7.11.1;Reactome: R-HSA-199418;Reactome: R-HSA-6804758;Reactome: R-HSA-8948751;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-69202;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;Reactome: R-HSA-6804759;Reactome: R-HSA-389513;Reactome: R-HSA-9634638;Reactome: R-HSA-198693;Reactome: R-HSA-111447	"Cyclin A:Cdk2-associated events at S phase entry";"RUNX2 regulates genes involved in cell migration";"TP53 Regulates Metabolic Genes";"AKT-mediated inactivation of FOXO1A";"CD28 dependent PI3K/Akt signaling";"AKT phosphorylates targets in the cytosol";"Downregulation of ERBB2:ERBB3 signaling";"RAB GEFs exchange GTP for GDP on RABs";"Human immunodeficiency virus 1 infection";"Negative regulation of the PI3K/AKT network";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN stability and activity";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Cyclin E associated events during G1/S transition";"mTOR signaling pathway";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Regulation of localization of FOXO transcription factors";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Activity through Association with Co-factors";"CTLA4 inhibitory signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"AKT phosphorylates targets in the nucleus";"Activation of BAD and translocation to mitochondria"
XP_046473227.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046485080.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046475500.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_046471390.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046474360.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046476120.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_046471618.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046472678.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710	"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy"
XP_046474704.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046492787.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046484263.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046487462.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046465094.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-432722	"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis"
XP_046479434.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046487739.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_046491646.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046477175.1	5	MetaCyc: PWY-7204;Reactome: R-HSA-6798695;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975	"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate"
XP_046472054.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)"
XP_046491038.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046468275.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-2892245;Reactome: R-HSA-8986944;Reactome: R-HSA-2892247;Reactome: R-HSA-452723;Reactome: R-HSA-6785807	"Deactivation of the beta-catenin transactivating complex";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Transcriptional Regulation by MECP2";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Transcriptional regulation of pluripotent stem cells";"Interleukin-4 and Interleukin-13 signaling"
XP_046491444.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046483443.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359	"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation"
XP_046467119.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046484790.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046489440.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_046482888.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046477052.1	4	KEGG: 00052+3.1.3.9;KEGG: 00010+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00500+3.1.3.9	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Starch and sucrose metabolism"
XP_046464856.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_046481746.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046465737.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046485968.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046480820.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046469285.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046475770.1	7	MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4	"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_046488282.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046470004.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046479621.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046471152.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_046470131.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046491629.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046474307.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046486005.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046477059.1	42	Reactome: R-HSA-912446;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-8939236;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-9610379;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-977225;Reactome: R-HSA-5625886;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-5617472	"Meiotic recombination";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"DNA methylation";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"HCMV Late Events";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046478496.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_046474742.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046482852.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046476835.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-983231;Reactome: R-HSA-8939236	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_046491702.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046472179.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046471277.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-1632852;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878	"RHO GTPases Activate Formins";"Intraflagellar transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Macroautophagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport"
XP_046474997.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046488415.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_046491774.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046486048.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046490464.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4	"Selenocompound metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Purine metabolism";"Assimilatory sulfate reduction III";"Selenate reduction";"Sulfur metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism"
XP_046491727.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046491307.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046476491.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046483589.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_046487202.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046487432.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_046490133.1	9	KEGG: 00790+3.5.4.16;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-5664	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_046485933.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046466814.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_046491576.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046480358.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046481627.1	33	Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-3232142	"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins"
XP_046471960.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046486195.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_046486372.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046481234.1	13	Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-983695	"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"PLC beta mediated events";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_046475505.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046484002.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046493372.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046484582.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_046492249.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-195253	"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex"
XP_046477612.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046470989.1	4	Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9	"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate"
XP_046477176.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046488923.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046480800.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046468647.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046471447.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046477640.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046473802.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046493013.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046468632.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046489594.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046474706.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046478084.1	10	Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-912446	"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination"
XP_046472147.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046489497.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_046471874.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046489556.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046485483.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046485385.1	7	Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36	"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_046491959.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_046483131.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046482944.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_046477303.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046475331.1	31	KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-7723;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-7858;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-6799;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-5366;MetaCyc: PWY-5971;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-7663;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-8012;MetaCyc: PWYG-321;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1	"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bacterial bioluminescence";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Gondoate biosynthesis (anaerobic)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)"
XP_046476981.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046475876.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046473237.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046486734.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046484976.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046477071.1	19	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-5389840;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Mitochondrial translation initiation";"Mitochondrial translation termination";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Mitochondrial translation elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046467938.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046473413.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046475413.1	4	KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III";"Arginine and proline metabolism"
XP_046477124.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046480106.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046482121.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046466501.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046484294.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046487996.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046488295.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046465744.1	7	KEGG: 00250+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_046480544.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Protein ubiquitination"
XP_046489513.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis"
XP_046489268.1	6	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-8876198;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"RAB GEFs exchange GTP for GDP on RABs";"Late endosomal microautophagy"
XP_046465900.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046465544.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_046468305.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046490911.1	11	Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_046491536.1	4	MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906	"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_046472568.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046492354.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657	"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes"
XP_046474712.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046476918.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
XP_046490768.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046471344.1	31	MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147;MetaCyc: PWY-8047;MetaCyc: PWY-5366;Reactome: R-HSA-199220;MetaCyc: PWY-5971;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-7858	"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Pederin biosynthesis";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II"
XP_046483576.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046475035.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046489015.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046469900.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046467023.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046483625.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_046474529.1	3	MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262	"L-carnitine biosynthesis";"Lysine degradation";"Carnitine synthesis"
XP_046487165.1	5	Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_046478629.1	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1	"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes"
XP_046479630.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046474768.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_046482491.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046489210.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_046479988.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046467931.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046486028.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046493413.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046486634.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_046470478.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_046482000.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046490341.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046483483.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046486746.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046473565.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046472877.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Ether lipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism"
XP_046490789.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046477006.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046476606.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046493103.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046476914.1	11	Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046469364.1	10	KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484	"Galactose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)"
XP_046483499.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_046470612.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046486190.1	6	KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11	"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism"
XP_046473175.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046469619.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_046466215.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176412	"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C"
XP_046477983.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_046468363.1	13	KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;MetaCyc: PWY-2261;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;Reactome: R-HSA-196836	"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism"
XP_046485620.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046482861.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_046482033.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046471860.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046469378.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046491797.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046486322.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_046484257.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_046482217.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_046469779.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046468892.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046484253.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046480201.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046470654.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-975634	"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Chylomicron assembly";"Chylomicron remodeling";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Scavenging by Class A Receptors";"LDL clearance";"Post-translational protein phosphorylation";"VLDL assembly";"Clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class H Receptors";"Retinoid metabolism and transport"
XP_046474892.1	9	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors"
XP_046491135.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046478022.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046473591.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"D-galactose detoxification";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_046478784.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046492743.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046482774.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_046481779.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046492256.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-9010553	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs"
XP_046467940.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046482859.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_046486578.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046469231.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046485473.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046474259.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046469032.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046465723.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_046482167.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046488542.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-432720	"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Lysosome Vesicle Biogenesis"
XP_046484908.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046472868.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046490386.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046475416.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_046473219.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51	"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism"
XP_046493107.1	9	KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_046468808.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046485077.1	11	Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"p38MAPK events";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_046469085.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_046483043.1	13	KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-7736;MetaCyc: PWY-7721	"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Methyl phomopsenoate biosynthesis"
XP_046492578.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_046487355.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906;MetaCyc: PWY-5514;Reactome: R-HSA-70171	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis"
XP_046473430.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046486720.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046477314.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046486797.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046470813.1	8	KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-5394;MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2	"Tyrosine metabolism";"Catecholamine biosynthesis";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis I";"Folate biosynthesis"
XP_046479135.1	4	KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193	"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046488589.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs"
XP_046489817.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046486376.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046478185.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046479294.1	7	MetaCyc: PWY-5941;MetaCyc: PWY-6724;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6737	"Glycogen degradation II";"Starch degradation II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V"
XP_046473467.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046478855.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046481387.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046481536.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046477762.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4"
XP_046490140.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046486911.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046482839.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_046480706.1	5	MetaCyc: PWY-2201;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20	"Folate transformations I";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate"
XP_046482817.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-8856828;Reactome: R-HSA-9613829;Reactome: R-HSA-5689880;Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8856825;Reactome: R-HSA-9646399	"RHO GTPases regulate CFTR trafficking";"Clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"Ub-specific processing proteases";"Late endosomal microautophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Cargo recognition for clathrin-mediated endocytosis";"Aggrephagy"
XP_046484166.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823	"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation"
XP_046492454.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046487146.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822	"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_046468535.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091	"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching"
XP_046468014.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046484279.1	15	Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-176034;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-9018519	"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression"
XP_046468879.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046481428.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046476626.1	10	Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_046480306.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046482872.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046465545.1	7	Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-983170	"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_046466695.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046490391.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046475582.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046479005.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046479508.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046474785.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046472366.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046468729.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046477765.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516	"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation"
XP_046488869.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046475006.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046472928.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling"
XP_046476959.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046480312.1	15	Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-1042	"Glycolysis";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)"
XP_046466001.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046483292.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_046465091.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Clathrin-mediated endocytosis"
XP_046477388.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046476829.1	18	Reactome: R-HSA-70268;KEGG: 00620+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-71403;Reactome: R-HSA-70895;Reactome: R-HSA-6783984;MetaCyc: PWY-5084;KEGG: 00010+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-5362517;KEGG: 00640+1.8.1.4;Reactome: R-HSA-389661;MetaCyc: PWY-5046;KEGG: 00020+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00380+1.8.1.4	"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citric acid cycle (TCA cycle)";"Branched-chain amino acid catabolism";"Glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycolysis / Gluconeogenesis";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Lysine catabolism";"Signaling by Retinoic Acid";"Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Citrate cycle (TCA cycle)";"Glycine, serine and threonine metabolism";"Tryptophan metabolism"
XP_046472610.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046476917.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
XP_046490279.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046469071.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046469377.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046477480.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_046475718.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor"
XP_046483064.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046475741.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046479089.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_046480097.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046473245.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046488370.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-210744	"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_046480647.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046473507.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046477595.1	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_046485291.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046467956.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046474807.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046479577.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046468745.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_046474897.1	9	Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-8849932	"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules"
XP_046487167.1	5	Reactome: R-HSA-193048;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_046489465.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046493247.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_046476785.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046468776.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046486690.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046478986.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_046468520.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046481085.1	5	Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621	"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine catabolism"
XP_046477152.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046485087.1	11	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"Human immunodeficiency virus 1 infection"
XP_046473386.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046479388.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046468774.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046472432.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046471966.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046489583.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_046482946.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_046481755.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046476519.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046484060.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046477596.1	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_046470905.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
XP_046473920.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046472351.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_046486496.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_046490143.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_046491585.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046480200.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046484911.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046487194.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046475364.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046483547.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_046470136.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046467899.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046479295.1	7	Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-5941	"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism";"Starch degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II";"Glycogen degradation II"
XP_046491170.1	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5632927	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH3"
XP_046469099.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_046473816.1	18	Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4	"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_046492355.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046492539.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046465989.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046479626.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046486403.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046467699.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046478313.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046477229.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_046485903.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_046466574.1	13	Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-419037	"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Collagen chain trimerization";"Laminin interactions";"Anchoring fibril formation";"NCAM1 interactions"
XP_046486709.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046492358.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046483965.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046465145.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046476292.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046469591.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046465247.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046488825.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046470116.1	57	Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610780	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome"
XP_046483289.1	8	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling"
XP_046482763.1	3	Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB"
XP_046489793.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046478340.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046474996.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046485929.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046485445.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046487461.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046489639.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_046490311.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046469021.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046469761.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046481775.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046472935.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722	"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex"
XP_046470452.1	4	Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation"
XP_046484064.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5689880	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases"
XP_046469735.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046486560.1	15	Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity"
XP_046464819.1	3	MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987	"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis"
XP_046468880.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046476002.1	6	MetaCyc: PWY-6364;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_046489022.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_046475991.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046477979.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_046474721.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_046466399.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046476493.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046478997.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046490173.1	7	KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71403;Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_046480415.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046491231.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_046489369.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046491792.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046469088.1	16	Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580	"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence"
XP_046474951.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046483575.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046476194.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046474139.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046469027.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046472721.1	4	MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046484954.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046488963.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046492722.1	7	Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046464924.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_046477549.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046487177.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442	"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs"
XP_046486921.1	5	KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33	"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_046473349.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase"
XP_046466126.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046475149.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046466895.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_046476721.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046487712.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046483484.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046489665.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046478275.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046471425.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046492367.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046479130.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046485335.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046479657.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046476408.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-72731	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP"
XP_046481161.1	60	MetaCyc: PWY-7726;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00640+4.2.1.17;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00720+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-7656;KEGG: 00623+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7216;MetaCyc: PWY-6883;KEGG: 00062+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-7606;Reactome: R-HSA-77348;MetaCyc: PWY-7779;MetaCyc: PWY-6944;MetaCyc: PWY-6435;MetaCyc: PWY-7654;KEGG: 00592+4.2.1.17;KEGG: 00650+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-5138;MetaCyc: PWY-6946;MetaCyc: PWY-7007;KEGG: 00062+4.2.1.17+1.1.1.211;Reactome: R-HSA-77346;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;Reactome: R-HSA-77350;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00903+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17;KEGG: 00380+4.2.1.17;Reactome: R-HSA-77285;MetaCyc: PWY-7778;MetaCyc: PWY-5136;KEGG: 00280+4.2.1.17;KEGG: 00627+4.2.1.17	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Geraniol degradation";"Geraniol degradation";"Glutaryl-coa degradation";"Propanoate metabolism";"Benzoate degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid degradation";"Lysine degradation";"Fatty acid salvage";"Carbon fixation pathways in prokaryotes";"Fermentation to 2-methylbutanoate";"Spodoptera littoralis pheromone biosynthesis";"Toluene degradation";"Benzoate degradation";"Acyl chain remodeling of CL";"Tryptophan metabolism";"Phenylalanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid elongation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Carbon fixation pathways in prokaryotes";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Methyl tert-butyl ether degradation";"Androstenedione degradation";"4-hydroxybenzoate biosynthesis III (plants)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"alpha-Linolenic acid metabolism";"Butanoate metabolism";"Caprolactam degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Methyl ketone biosynthesis (engineered)";"Fatty acid elongation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid degradation";"Fatty acid degradation";"beta-Alanine metabolism";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Limonene and pinene degradation";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Pyruvate fermentation to butanol I";"Valine, leucine and isoleucine degradation";"Caprolactam degradation";"Tryptophan metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"2-methylpropene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Valine, leucine and isoleucine degradation";"Aminobenzoate degradation"
XP_046493376.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046467471.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046470869.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046493174.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046469716.1	13	KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-2871796;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-202433;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;Reactome: R-HSA-9027277;KEGG: 04070+3.1.4.11	"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidylinositol signaling system"
XP_046470434.1	5	MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
XP_046467117.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046484789.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046468627.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046470089.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046478805.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046486488.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837	"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation"
XP_046470431.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046480910.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046476139.1	17	Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5789;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5744;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425	"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism"
XP_046472331.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046488308.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046490085.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046467932.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046470569.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046468534.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105	"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation"
XP_046475580.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046491789.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046482628.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046489106.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046488221.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046484189.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_046493374.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046467963.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046487157.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046480212.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046481965.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464	"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins"
XP_046490712.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046489969.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-195253	"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex"
XP_046468648.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046482214.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046491410.1	3	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)"
XP_046472890.1	14	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism"
XP_046465590.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046479029.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046467014.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_046466930.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046489040.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_046465170.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046490875.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046490605.1	13	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9649948	"Human immunodeficiency virus 1 infection";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Human cytomegalovirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human papillomavirus infection";"Signaling downstream of RAS mutants"
XP_046477308.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046488754.1	5	KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_046482623.1	4	MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism"
XP_046492002.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_046487648.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046472213.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046476653.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046471885.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_046482860.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_046476422.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_046475446.1	7	Reactome: R-HSA-77111;KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074	"Synthesis of Ketone Bodies";"Valine, leucine and isoleucine degradation";"Peroxisomal protein import";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Geraniol degradation";"Mevalonate degradation"
XP_046470466.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046479671.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-166208	"Deadenylation of mRNA";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling"
XP_046474564.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_046473564.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046486704.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046479629.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046481596.1	10	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"RSK activation";"Relaxin signaling pathway";"mTOR signaling pathway";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_046471906.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046476789.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046490129.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046469966.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046464784.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046470974.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046470440.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046480679.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046472058.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Photosynthesis";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation"
XP_046475557.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_046492191.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_046485124.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_046482377.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046473633.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_046492126.1	6	MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151	"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046475677.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Purine metabolism"
XP_046488953.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_046471678.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046473573.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046469205.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046488830.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046489303.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046480465.1	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
XP_046488609.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046471110.1	31	MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-7746;MetaCyc: PWY-6799;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-7858;MetaCyc: PWY-8049;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-5366;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5989	"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Pederin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)"
XP_046471340.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168	"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)"
XP_046479415.1	11	Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_046480666.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240	"Amino acid transport across the plasma membrane";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism"
XP_046481953.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046483337.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046466803.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046491149.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046473674.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046465656.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046474943.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046468658.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046478336.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046469596.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046473944.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046466445.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_046470712.1	10	KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7571;MetaCyc: PWY-6174	"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Butanoate metabolism";"PPARA activates gene expression";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)"
XP_046466507.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046491775.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046479096.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046466131.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046479794.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046465256.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046487256.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_046474018.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046466928.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_046482159.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046492630.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Neutrophil degranulation"
XP_046488738.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046475462.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955	"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Long-term potentiation";"RAF/MAP kinase cascade";"RAF activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_046487035.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046466480.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046490543.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330	"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_046491105.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046480019.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-113507	"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation"
XP_046490315.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046477467.1	11	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046489801.1	4	Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356	"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_046473468.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046470898.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_046483852.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046485638.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046470433.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046481658.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046467271.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046489910.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046491601.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046478301.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046484946.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046471000.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046478259.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046485062.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046489474.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046465934.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046472795.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046484297.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046468630.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046485292.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_046485237.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046475040.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046467677.1	56	Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-983168	"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046483178.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_046489263.1	6	Reactome: R-HSA-9615710;Reactome: R-HSA-8876198;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"Late endosomal microautophagy";"RAB GEFs exchange GTP for GDP on RABs";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_046476758.1	3	Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_046489852.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046482626.1	13	Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;MetaCyc: PWY-6902	"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)"
XP_046488198.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046490314.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046478752.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046479748.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046479010.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046493291.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_046489894.1	3	KEGG: 00901+2.7.1.222;Reactome: R-HSA-189085;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Digestion of dietary carbohydrate";"Psilocybin biosynthesis"
XP_046492185.1	11	MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210455;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2	"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis"
XP_046479950.1	12	Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238	"Glycogen synthesis";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Sucrose biosynthesis II"
XP_046484280.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167290	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation"
XP_046492574.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_046471307.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046493181.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046471560.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046479245.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046475874.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046488647.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_046489752.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_046491359.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_046481468.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_046473085.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046473622.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046465629.1	5	KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-6168	"Riboflavin metabolism";"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)"
XP_046490729.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046488733.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046467220.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046478458.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046464785.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046493377.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046471413.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_046472463.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046479394.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046470678.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046488932.1	6	MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_046475951.1	4	Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_046470669.1	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046464885.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046470078.1	16	Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-164939;Reactome: R-HSA-8964038;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-196025;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-437239	"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Nef mediated downregulation of CD28 cell surface expression";"LDL clearance";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Formation of annular gap junctions";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"Recycling pathway of L1"
XP_046472431.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046485028.1	11	KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-7184	"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_046468307.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046472056.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046486899.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis"
XP_046469717.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166	"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA"
XP_046477090.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046478743.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046468223.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046490987.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046476485.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046476786.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046469070.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046482053.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046476507.1	19	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-418885	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"G beta:gamma signalling through CDC42";"EGFR downregulation";"Myogenesis";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling"
XP_046480209.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046482566.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046468465.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046493179.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046476031.1	5	KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-7761;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_046467266.1	13	Reactome: R-HSA-1660662;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857	"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation"
XP_046475525.1	7	Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_046475969.1	16	Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1963640;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-1227986;Reactome: R-HSA-1250347;Reactome: R-HSA-1251985;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795	"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GRB2 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"Signaling by ERBB2";"SHC1 events in ERBB4 signaling";"Nuclear signaling by ERBB4";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling"
XP_046484942.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_046487849.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_046492388.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_046485073.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046465695.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046490593.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_046493354.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_046470071.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046491080.1	13	MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes"
XP_046487046.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046489416.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046465216.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046477339.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046488283.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046492756.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046468476.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046483604.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_046485137.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046474513.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_046465532.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046485431.1	7	MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00680+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism"
XP_046479962.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046492043.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676	"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_046481621.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046475001.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_046474203.1	29	Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-6804757;Reactome: R-HSA-3371453;Reactome: R-HSA-912446;Reactome: R-HSA-349425;Reactome: R-HSA-69473;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-6803207;Reactome: R-HSA-2559586;Reactome: R-HSA-69541;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-6803204;Reactome: R-HSA-5693607	"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Degradation";"Regulation of HSF1-mediated heat shock response";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M DNA damage checkpoint";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of Caspase Activators and Caspases";"DNA Damage/Telomere Stress Induced Senescence";"Stabilization of p53";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"Human immunodeficiency virus 1 infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Processing of DNA double-strand break ends"
XP_046466645.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046480540.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046476677.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046472443.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_046477456.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046468499.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046473455.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046474429.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046481491.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_046482602.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046471467.1	6	Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712	"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling"
XP_046488560.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046472964.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046467818.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046480563.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046474630.1	16	Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-167238	"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_046471617.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046475017.1	14	Reactome: R-HSA-500657;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-399997;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-418217;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11	"Presynaptic function of Kainate receptors";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G beta:gamma signalling through PLC beta";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Ca2+ pathway";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system"
XP_046469042.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046492742.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046472955.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA"
XP_046490091.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046478261.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046493132.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_046467182.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046475958.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046474911.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046489545.1	4	MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27	"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_046482690.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_046481344.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046468297.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046469031.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046469766.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046491361.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_046478890.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046492129.1	6	KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5664	"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_046486374.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046471059.1	5	KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403	"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling"
XP_046477300.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046482549.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046476026.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_046472904.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046464781.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046471733.1	5	KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3	"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate biosynthesis"
XP_046491142.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046480240.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_046481251.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_046473088.1	12	MetaCyc: PWY-1861;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Gluconeogenesis";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)"
XP_046478234.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_046470030.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046475303.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046481699.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins"
XP_046476063.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins"
XP_046477319.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046471066.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046467629.1	17	Reactome: R-HSA-1912408;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-2559580;Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-113501;Reactome: R-HSA-2559585;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-9616222;Reactome: R-HSA-8953750;Reactome: R-HSA-111448;Reactome: R-HSA-69205	"Pre-NOTCH Transcription and Translation";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oncogene Induced Senescence";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of granulopoiesis";"Transcriptional Regulation by E2F6";"Activation of NOXA and translocation to mitochondria";"G1/S-Specific Transcription"
XP_046474853.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_046471354.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Gap junction assembly";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_046485823.1	10	MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations I";"Folate transformations II (plants)";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)"
XP_046491810.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046472860.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_046482921.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_046484796.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046476529.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_046491588.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046483023.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619	"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN"
XP_046486540.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046485880.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-2151201;Reactome: R-HSA-3214847	"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis";"HATs acetylate histones"
XP_046468020.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046476718.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046485415.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046489262.1	6	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-8876198;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Late endosomal microautophagy";"HCMV Late Events";"RAB GEFs exchange GTP for GDP on RABs";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046465276.1	3	KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_046466298.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046492738.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids"
XP_046466629.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046479000.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046487917.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604	"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling"
XP_046476000.1	6	MetaCyc: PWY-6363;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183	"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_046484349.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046490198.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046479015.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046469230.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046492306.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy"
XP_046476274.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046475034.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046466490.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_046481924.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046472203.1	12	Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism"
XP_046470439.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046475030.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046475563.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046481079.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046469414.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046485938.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_046485941.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_046484719.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046466449.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046469588.1	7	KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;MetaCyc: PWY-6363	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_046480282.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046469849.1	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921	"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_046483549.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_046484239.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046475927.1	11	Reactome: R-HSA-912694;Reactome: R-HSA-512988;Reactome: R-HSA-909733;Reactome: R-HSA-432142;Reactome: R-HSA-388841;Reactome: R-HSA-210990;Reactome: R-HSA-114604;Reactome: R-HSA-391160;Reactome: R-HSA-9008059;Reactome: R-HSA-389948;Reactome: R-HSA-877312	"Regulation of IFNA signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interferon alpha/beta signaling";"Platelet sensitization by LDL";"Costimulation by the CD28 family";"PECAM1 interactions";"GPVI-mediated activation cascade";"Signal regulatory protein family interactions";"Interleukin-37 signaling";"PD-1 signaling";"Regulation of IFNG signaling"
XP_046486937.1	9	KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_046490166.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046467306.1	9	KEGG: 00350+2.6.1.5;KEGG: 00960+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00270+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5	"Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine catabolism";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_046465093.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation"
XP_046479285.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046485957.1	7	Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_046492360.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046490521.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046471322.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943	"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_046488895.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046484351.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490	"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation"
XP_046474503.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046473365.1	7	MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10	"UMP biosynthesis I";"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_046492584.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_046477275.1	12	MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism"
XP_046480025.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_046484193.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046467037.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046486543.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-201722;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"Circadian Clock";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression"
XP_046479126.1	7	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation"
XP_046482139.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046487674.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_046492392.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase"
XP_046479653.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_046479949.1	12	KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-3322077	"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis"
XP_046490092.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046466519.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046492592.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046490195.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046477574.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046487981.1	27	KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5610785;Reactome: R-HSA-5250924;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4641262;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-3371453;Reactome: R-HSA-5358747;Reactome: R-HSA-399956;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5467348;KEGG: 04151+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-5674400;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;KEGG: 05165+2.7.11.1;Reactome: R-HSA-195253	"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"GLI3 is processed to GLI3R by the proteasome";"B-WICH complex positively regulates rRNA expression";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Relaxin signaling pathway";"mTOR signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Human cytomegalovirus infection";"APC truncation mutants have impaired AXIN binding";"Regulation of HSF1-mediated heat shock response";"S33 mutants of beta-catenin aren't phosphorylated";"CRMPs in Sema3A signaling";"Thermogenesis";"Truncations of AMER1 destabilize the destruction complex";"PI3K-Akt signaling pathway";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by AKT1 E17K in Cancer";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Degradation of beta-catenin by the destruction complex"
XP_046469752.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046476934.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_046465655.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046483844.1	20	MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Jasmonic acid biosynthesis"
XP_046488184.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046482941.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046470155.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046467104.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046464718.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046491940.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046472189.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_046474801.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046481426.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046489919.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_046489008.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046464829.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway"
XP_046479948.1	12	Reactome: R-HSA-3322077;MetaCyc: PWY-7817;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9	"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Glycerolipid metabolism"
XP_046473234.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046479266.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation"
XP_046466302.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046472046.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-6453	"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis"
XP_046472489.1	5	KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;MetaCyc: PWY-7918;Reactome: R-HSA-532668;MetaCyc: PWY-7919	"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)"
XP_046486801.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046479254.1	5	Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16	"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation"
XP_046482094.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046473149.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046467486.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046487413.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046474258.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_046478781.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_046476628.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-9613354	"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy"
XP_046489315.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046480373.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046474634.1	16	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-983168	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Neddylation";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046472226.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046478270.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046487389.1	5	KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism"
XP_046483519.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046466444.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046489943.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_046466537.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_046479937.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046489816.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046466747.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046478999.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046471822.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_046466746.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046468986.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_046479537.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_046471012.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_046475281.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046468539.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046465065.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_046476007.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes"
XP_046465119.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids"
XP_046480283.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046491785.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046487610.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046486856.1	10	Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11	"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis"
XP_046480692.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_046473426.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046468571.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_046476065.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046464854.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_046480674.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046481888.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046487838.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046492637.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046478561.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5466	"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis"
XP_046479654.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046481191.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_046493170.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885	"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins"
XP_046492654.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy"
XP_046490611.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_046491175.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046477519.1	19	MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-5392;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-163765;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8	"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"ChREBP activates metabolic gene expression";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Neutrophil degranulation";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes"
XP_046469090.1	16	Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585	"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence"
XP_046474272.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046465535.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046490384.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046490684.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046487832.1	24	Reactome: R-HSA-9634635;Reactome: R-HSA-1257604;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-444257;Reactome: R-HSA-2730905;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-114604;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400	"Estrogen-stimulated signaling through PRKCZ";"PIP3 activates AKT signaling";"Integrin signaling";"Human cytomegalovirus infection";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"Relaxin signaling pathway";"FCERI mediated NF-kB activation";"RSK activation";"Role of LAT2/NTAL/LAB on calcium mobilization";"RHO GTPases activate PKNs";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"GPVI-mediated activation cascade";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"Activation of AKT2";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_046487915.1	5	Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558	"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_046464879.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_046481383.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046480471.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_046491799.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046466464.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046489963.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_046490040.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046484865.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046491796.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046492700.1	7	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_046465600.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_046466366.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_046466174.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046480005.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046478906.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046491461.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046481443.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046477515.1	10	Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-400206;Reactome: R-HSA-8936459	"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046473572.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046489873.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046476240.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046484644.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046477517.1	19	MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-75105;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-7384;KEGG: 00720+2.3.3.8	"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes"
XP_046482880.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_046484863.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis"
XP_046486872.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046478588.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_046471681.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046492033.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_046492116.1	19	Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-3000497	"Chylomicron remodeling";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Chylomicron assembly";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"VLDL assembly";"VLDL clearance";"Scavenging by Class A Receptors";"LDL clearance";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Scavenging by Class H Receptors"
XP_046472652.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046490649.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046474939.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046465693.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046479261.1	18	MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7416	"Anandamide biosynthesis I";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_046491631.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046473320.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046465317.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046474720.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_046483149.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_046478623.1	15	Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-111465	"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins"
XP_046470555.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046484242.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046465071.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046478125.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046468299.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046486138.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046491825.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046479460.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001	"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Neutrophil degranulation";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade"
XP_046468712.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046481515.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Purine metabolism"
XP_046481992.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046478443.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046490674.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046470137.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046487054.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_046464984.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_046492775.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046468547.1	25	Reactome: R-HSA-8939256;Reactome: R-HSA-8936459;Reactome: R-HSA-8941332;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8939245;Reactome: R-HSA-8941326;Reactome: R-HSA-8939236;Reactome: R-HSA-8949275;Reactome: R-HSA-8939242;Reactome: R-HSA-8939243;Reactome: R-HSA-8940973;Reactome: R-HSA-8939902;Reactome: R-HSA-8951936;Reactome: R-HSA-8878166;Reactome: R-HSA-8941858;Reactome: R-HSA-8939246;Reactome: R-HSA-8931987;Reactome: R-HSA-8934593;Reactome: R-HSA-9616222;Reactome: R-HSA-8941333;Reactome: R-HSA-8941284;Reactome: R-HSA-8935964;Reactome: R-HSA-8951911;Reactome: R-HSA-8939247	"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates genes involved in cell migration";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX2 expression and activity";"RUNX3 regulates p14-ARF";"Transcriptional regulation by RUNX2";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates expression of components of tight junctions";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling"
XP_046489602.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046492482.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy"
XP_046465915.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046471933.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046490371.1	14	Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery"
XP_046465968.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_046483706.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_046466771.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046483845.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7726	"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_046471752.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046476484.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046476658.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046484245.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046491798.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046477768.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_046488868.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046472895.1	14	KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409	"Ether lipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_046491096.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046492590.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046491424.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046491104.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046479483.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046482350.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-110331	"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine"
XP_046475493.1	19	Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-438066	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"RAF activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_046486981.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_046483061.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046489212.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"Neddylation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_046480860.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046482644.1	13	MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-1660662	"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism"
XP_046466190.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_046469467.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046481644.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046489974.1	22	Reactome: R-HSA-2467813;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins"
XP_046474309.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046476483.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046471347.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_046468123.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046471153.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_046491844.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046489507.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_046469461.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046465711.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_046476361.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046485078.1	11	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302	"Human cytomegalovirus infection";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation"
XP_046469792.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex"
XP_046480861.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046480248.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046483829.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-2206292	"Neutrophil degranulation";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"MPS VII - Sly syndrome"
XP_046484939.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046487634.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046475542.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-438066	"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Long-term potentiation";"RAF/MAP kinase cascade";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_046491517.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046476949.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046492372.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046470981.1	8	MetaCyc: PWY-66;MetaCyc: PWY-5738;MetaCyc: PWY-7573;MetaCyc: PWY-5739;KEGG: 00051+4.2.1.47;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5740	"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-D-perosamine biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis"
XP_046479874.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046476119.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_046484145.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046480542.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_046482403.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046486035.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046488413.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_046483088.1	8	KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-5683826	"Purine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Surfactant metabolism"
XP_046474519.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_046465176.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046483964.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046491232.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_046488024.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046477297.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046493238.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046492488.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046484277.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046467249.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046470939.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-114608	"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation"
XP_046488195.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046487592.1	19	Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825	"VLDL clearance";"Clathrin-mediated endocytosis";"VLDL assembly";"Post-translational protein phosphorylation";"LDL clearance";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Chylomicron clearance";"Chylomicron assembly";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis"
XP_046482166.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_046482224.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046480105.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046479677.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-429947	"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Deadenylation of mRNA"
XP_046482971.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_046465756.1	7	KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;MetaCyc: PWY-7158;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134	"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"L-tyrosine biosynthesis IV"
XP_046488152.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_046481513.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555	"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events"
XP_046473111.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046478891.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids"
XP_046478100.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046489647.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046480702.1	3	KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_046468579.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046492960.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001	"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_046478995.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046469091.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398	"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway"
XP_046484552.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_046480817.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription"
XP_046470204.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046484354.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_046480046.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046485463.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046466512.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046487331.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046479021.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046491580.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046474964.1	18	MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4	"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Linoleic acid metabolism"
XP_046475699.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046481465.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046489703.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_046475282.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046490692.1	12	MetaCyc: PWY-5108;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-6672;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857	"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis"
XP_046490363.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_046483143.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046470616.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046488838.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046480575.1	10	MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-5484	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_046473241.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046469193.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046490914.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346	"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of DVL";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis"
XP_046478169.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046484962.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046490381.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046485703.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046485447.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046482871.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046468985.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_046485806.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046472122.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046476070.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046490280.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046471273.1	10	Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5891;MetaCyc: PWY-5844;MetaCyc: PWY-5890;MetaCyc: PWY-5849;MetaCyc: PWY-5895;MetaCyc: PWY-7996;MetaCyc: PWY-5839;MetaCyc: PWY-5892	"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis"
XP_046475100.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046489514.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_046490715.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046472545.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_046485361.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_046475807.1	11	Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475	"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046465575.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046491109.1	6	Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010	"Serine biosynthesis";"Cysteine and methionine metabolism";"Methane metabolism";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
XP_046477142.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046477008.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046484500.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046481939.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046485065.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046480824.1	4	KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16	"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_046487144.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-168333	"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_046483939.1	4	MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism"
XP_046467749.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046483122.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_046473221.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7589	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_046487525.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_046492180.1	4	KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046470074.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046472361.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046492724.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_046465617.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_046484864.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_046493115.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_046475565.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis"
XP_046480625.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046477832.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046489468.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360	"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_046484200.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046469646.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046484917.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167246	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript"
XP_046465254.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046489667.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046466987.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046480968.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_046490119.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046474722.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_046487278.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_046467716.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046470611.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046487916.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604	"PI3K Cascade";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling"
XP_046468980.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046488871.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046478106.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046477833.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046484095.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_046487931.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046487098.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046472306.1	2	MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_046477276.1	12	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046482831.1	9	Reactome: R-HSA-8856825;Reactome: R-HSA-9646399;Reactome: R-HSA-5627083;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"Cargo recognition for clathrin-mediated endocytosis";"Aggrephagy";"RHO GTPases regulate CFTR trafficking";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"Late endosomal microautophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046477431.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046476336.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046479882.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046478991.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046479012.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046484708.1	24	Reactome: R-HSA-164378;Reactome: R-HSA-8963896;Reactome: R-HSA-9634600;Reactome: R-HSA-442720;Reactome: R-HSA-9010642;Reactome: R-HSA-983231;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163358;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-111931;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-5621575;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-8853659;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-392517;Reactome: R-HSA-163560;Reactome: R-HSA-4420097	"PKA activation in glucagon signalling";"HDL assembly";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"ROBO receptors bind AKAP5";"Factors involved in megakaryocyte development and platelet production";"mTOR signaling pathway";"PKA-mediated phosphorylation of key metabolic factors";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"PKA activation";"Hedgehog 'off' state";"PKA-mediated phosphorylation of CREB";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"CD209 (DC-SIGN) signaling";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"RET signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"Rap1 signalling";"Triglyceride catabolism";"VEGFA-VEGFR2 Pathway"
XP_046490170.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046472855.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-936440	"Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_046492216.1	6	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination"
XP_046487317.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046476306.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_046480822.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046466319.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_046486761.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046484234.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046484340.1	20	KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6	"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism"
XP_046480250.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046469770.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046488109.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046482882.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046492711.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_046485407.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046484797.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046480565.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046469369.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_046479871.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_046486507.1	12	Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-6978;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5857	"Ubiquinol biosynthesis";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_046475705.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046492371.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046484906.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046478613.1	15	Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated"
XP_046491069.1	17	Reactome: R-HSA-1834949;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-3270619;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756	"Cytosolic sensors of pathogen-associated DNA";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"IRF3-mediated induction of type I IFN";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation"
XP_046489942.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_046480107.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046492669.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046467814.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046490097.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046489673.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046471965.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046488200.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046483427.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_046481126.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_046466611.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046482276.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046481763.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046486163.1	5	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_046484945.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046470749.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046486762.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046492703.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046471064.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_046477325.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046481772.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_046472594.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046467960.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_046466463.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046483132.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046476592.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046475575.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7589	"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_046471926.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins"
XP_046479744.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046491249.1	57	Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-69601	"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_046473246.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046470145.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046479301.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-7238;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25	"Neutrophil degranulation";"Starch degradation II";"Sucrose biosynthesis II";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism"
XP_046472176.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046468866.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046476471.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046483160.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046469284.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046488702.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046470226.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046466610.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046467109.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_046471497.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046481511.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_046489683.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_046468891.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046493124.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_046477235.1	6	MetaCyc: PWY-5514;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_046479371.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046479674.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046473460.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046468425.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_046484620.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import"
XP_046480180.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046492553.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046466091.1	14	MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-1622;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-2221	"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_046472956.1	7	KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25	"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system"
XP_046477491.1	33	Reactome: R-HSA-69656;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-674695	"Cyclin A:Cdk2-associated events at S phase entry";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events"
XP_046468682.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046473101.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046481670.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046487319.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046471398.1	12	MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-601	"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan"
XP_046483718.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_046465064.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_046477639.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_046489217.1	4	KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046487354.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046467547.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046482216.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046481266.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046475576.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166	"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PA"
XP_046491645.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046478915.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_046476116.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_046489506.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins"
XP_046471200.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
XP_046479018.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046489593.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046470165.1	10	Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-9635644	"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair"
XP_046467315.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046480633.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_046466364.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_046492120.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046472480.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046490189.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046474280.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_046470432.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046472210.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046489494.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_046486284.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046484887.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046472632.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558	"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_046465009.1	9	KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263	"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_046480514.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046488416.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_046488995.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_046468259.1	6	KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-446199	"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate"
XP_046479459.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-264870;Reactome: R-HSA-373753	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions"
XP_046475866.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_046476691.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_046476488.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046472478.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046468426.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046473337.1	6	KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23	"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_046478646.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046464713.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046472099.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046480924.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046481890.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046470039.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046491301.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_046491204.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046469360.1	6	Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species"
XP_046476834.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-383280;Reactome: R-HSA-8939236	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_046474929.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046470587.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046474713.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046478519.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046486222.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046479016.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046479560.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_046465904.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046468889.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046467924.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046470983.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition"
XP_046475800.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_046471811.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_046479054.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046474067.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046470843.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046490752.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046465778.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway"
XP_046490644.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046467288.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046476179.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046467789.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis"
XP_046478087.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046466418.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046483869.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046475018.1	14	MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418217;Reactome: R-HSA-1855204;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-500657;MetaCyc: PWY-8052;MetaCyc: PWY-6367	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G beta:gamma signalling through PLC beta";"Synthesis of IP3 and IP4 in the cytosol";"Ca2+ pathway";"PLC beta mediated events";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_046475748.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046482378.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046475742.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046485266.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046469016.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046485259.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046477128.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046487651.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046491710.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_046474491.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046472412.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046479184.1	12	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-76061;Reactome: R-HSA-73780	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation"
XP_046466192.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046490187.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046491360.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_046471979.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
XP_046466804.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046468639.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_046469598.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046476048.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046488822.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046492992.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046478442.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_046468686.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046484101.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_046466725.1	6	KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation"
XP_046483546.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation"
XP_046490402.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_046468661.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046466452.1	3	KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3	"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism"
XP_046485438.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046487257.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046476725.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046492538.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_046489484.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046488602.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046478597.1	15	Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348	"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex"
XP_046465500.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046476467.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046487973.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046488038.1	13	Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"LDL clearance";"VLDLR internalisation and degradation";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_046467201.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_046467313.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046478569.1	6	MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_046474056.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68949	"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin"
XP_046488322.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_046474909.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046469617.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046467279.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046485613.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046489698.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition"
XP_046490668.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046468730.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046482305.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046475745.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046487467.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046465654.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046484834.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046470984.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362300	"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_046471930.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-8939236	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_046472006.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046482154.1	8	KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-6609	"Purine metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Surfactant metabolism";"Adenine and adenosine salvage III"
XP_046474893.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046478594.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333	"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated"
XP_046486065.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046485089.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046475283.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046484778.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_046477302.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046468016.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046473860.1	8	Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_046488256.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046492586.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_046487041.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046474609.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046491592.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046487700.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046469822.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046476724.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046468925.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046490338.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046474497.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046467525.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_046490010.1	5	Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_046491990.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046491788.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046476503.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046482564.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046472993.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046482164.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_046480519.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046491791.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046481236.1	13	Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-139853	"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels"
XP_046492671.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046477327.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046486867.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis"
XP_046469223.1	4	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_046492187.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046464992.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046469096.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681	"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT"
XP_046469007.1	16	Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7124;Reactome: R-HSA-70263;MetaCyc: PWY-7218;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-1042	"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Methane metabolism";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)"
XP_046479796.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046488965.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046469374.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_046469439.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046482241.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046486457.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046476624.1	6	Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-416993;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_046471677.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046480717.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046477279.1	12	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046483144.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046467381.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046487549.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046467157.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_046490142.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_046478021.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_046466596.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046474180.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046479167.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046469359.1	6	Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import"
XP_046477493.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex"
XP_046470897.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_046485434.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis"
XP_046475564.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046490925.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046464982.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046473925.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_046471211.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046487920.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046470135.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046481630.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046490915.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-8939236	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_046491417.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046480853.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046484243.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046468479.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046488821.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046485940.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_046493177.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046490321.1	8	Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841	"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"HCMV Early Events";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines"
XP_046482975.1	6	MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3	"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophospholipid metabolism"
XP_046469437.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046488716.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055	"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis"
XP_046474624.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_046489310.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046480513.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046467668.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046491525.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046490278.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046468840.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_046491776.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046466717.1	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_046481139.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_046490025.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046490834.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046491987.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046480059.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046487635.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046488593.1	34	Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-69656;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"Cyclin A:Cdk2-associated events at S phase entry";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape"
XP_046488677.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_046482122.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046472671.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046486764.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046491524.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046485942.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_046483741.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046469391.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046491431.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_046487387.1	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_046475461.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046468565.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046468568.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_046470774.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046482195.1	20	Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI"
XP_046484384.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_046470754.1	13	MetaCyc: PWY-8052;Reactome: R-HSA-2871796;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;Reactome: R-HSA-9027277;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-202433	"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules"
XP_046467015.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_046478715.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046468458.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046470975.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046481747.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046484589.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046489511.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis"
XP_046468543.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046478558.1	3	KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K"
XP_046479658.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046466426.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046476342.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_046478388.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046481386.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046479953.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695	"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events"
XP_046479940.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695	"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events"
XP_046471571.1	11	MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6999;MetaCyc: PWY-6596;MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-6607;Reactome: R-HSA-8851680	"Guanosine nucleotides degradation III";"Purine metabolism";"Purine catabolism";"Theophylline degradation";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Butyrophilin (BTN) family interactions"
XP_046484022.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046468035.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046483913.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046485970.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046473114.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046477777.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144	"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_046476784.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046487969.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046475204.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046491667.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_046483338.1	5	Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407	"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_046470167.1	10	Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-9635644	"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair"
XP_046465917.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046485943.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_046492536.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046465073.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046477333.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046491641.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046479084.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046467247.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046468427.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046473177.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046465908.1	32	Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167158	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex"
XP_046481303.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046487425.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046488933.1	6	Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13	"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_046491097.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-1042	"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)"
XP_046478897.1	33	Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-159236	"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046466595.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046493232.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046483123.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046473091.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_046478827.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_046478207.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_046476041.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046466238.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046473797.1	44	Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-879415;Reactome: R-HSA-8939211;Reactome: R-HSA-74749;Reactome: R-HSA-9635465;Reactome: R-HSA-2559580;Reactome: R-HSA-6802948;Reactome: R-HSA-202670;Reactome: R-HSA-456926;KEGG: 04150+2.7.11.24;Reactome: R-HSA-445144;Reactome: R-HSA-2559585;Reactome: R-HSA-2871796;Reactome: R-HSA-5674499;Reactome: R-HSA-450341;Reactome: R-HSA-8943724;Reactome: R-HSA-5663213;Reactome: R-HSA-1295596;Reactome: R-HSA-5654732;Reactome: R-HSA-5668599;Reactome: R-HSA-982772;Reactome: R-HSA-5674135;Reactome: R-HSA-5654726;Reactome: R-HSA-444257;Reactome: R-HSA-5673001;Reactome: R-HSA-5654733;Reactome: R-HSA-6811558;Reactome: R-HSA-112409;Reactome: R-HSA-6802952;Reactome: R-HSA-375165;Reactome: R-HSA-8940973;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-3371453;Reactome: R-HSA-881907;Reactome: R-HSA-2029482;Reactome: R-HSA-2559582;Reactome: R-HSA-170968;Reactome: R-HSA-198753;Reactome: R-HSA-162658;Reactome: R-HSA-9634638;Reactome: R-HSA-9627069;Reactome: R-HSA-5654727	"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Advanced glycosylation endproduct receptor signaling";"ESR-mediated signaling";"Signal attenuation";"Suppression of apoptosis";"Oxidative Stress Induced Senescence";"Signaling by high-kinase activity BRAF mutants";"ERKs are inactivated";"Thrombin signalling through proteinase activated receptors (PARs)";"mTOR signaling pathway";"Signal transduction by L1";"Oncogene Induced Senescence";"FCERI mediated MAPK activation";"Negative feedback regulation of MAPK pathway";"Activation of the AP-1 family of transcription factors";"Regulation of PTEN gene transcription";"RHO GTPases Activate WASPs and WAVEs";"Spry regulation of FGF signaling";"Negative regulation of FGFR3 signaling";"RHO GTPases Activate NADPH Oxidases";"Growth hormone receptor signaling";"MAP2K and MAPK activation";"Negative regulation of FGFR1 signaling";"RSK activation";"RAF/MAP kinase cascade";"Negative regulation of FGFR4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF-independent MAPK1/3 activation";"Signaling by BRAF and RAF fusions";"NCAM signaling for neurite out-growth";"RUNX2 regulates osteoblast differentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Regulation of HSF1-mediated heat shock response";"Gastrin-CREB signalling pathway via PKC and MAPK";"Regulation of actin dynamics for phagocytic cup formation";"Senescence-Associated Secretory Phenotype (SASP)";"Frs2-mediated activation";"ERK/MAPK targets";"Golgi Cisternae Pericentriolar Stack Reorganization";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of the apoptosome activity";"Negative regulation of FGFR2 signaling"
XP_046464874.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046486088.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_046469190.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046487049.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046475553.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-442982	"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"RAF activation";"Ion transport by P-type ATPases";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_046492605.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_046480854.1	9	MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle"
XP_046474948.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046467592.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046483219.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046477323.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046478807.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_046480252.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046477733.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046467970.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046489939.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_046476520.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046490206.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046490407.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046477072.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046465718.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046469411.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046471202.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046469618.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_046466934.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046475507.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046472448.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_046473954.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046485388.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046469410.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046468182.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046484891.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046465906.1	32	Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167161	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation"
XP_046468754.1	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection"
XP_046483145.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046477466.1	11	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2"
XP_046472227.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046469769.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046493326.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046485322.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046471084.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046468700.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046466541.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046471114.1	31	MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-7723;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-7663;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-6519;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-8012;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-7746	"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Pederin biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Gondoate biosynthesis (anaerobic)";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis"
XP_046478610.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358752	"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated"
XP_046484830.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944	"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2"
XP_046486857.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_046465558.1	5	Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway"
XP_046479375.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046466585.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_046482803.1	5	MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism"
XP_046487423.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046489464.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046482455.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046474917.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046479968.1	8	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_046472167.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046486107.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046479260.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482925	"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PG"
XP_046472311.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046485771.1	52	Reactome: R-HSA-167161;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-76061;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-1834949;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-72165	"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Minor Pathway"
XP_046467127.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046465186.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046475061.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046471762.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046475945.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046488347.1	5	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-201722	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex"
XP_046489214.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_046474709.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046471338.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism"
XP_046473294.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046492983.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046487792.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_046472961.1	7	KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25	"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system"
XP_046493078.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046482233.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046480573.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_046489790.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046473946.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046468871.1	9	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Neutrophil degranulation";"MAP2K and MAPK activation";"mTOR signalling"
XP_046487951.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046477610.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046466981.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046472234.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046480570.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046476686.1	4	KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823;Reactome: R-HSA-947581;MetaCyc: PWY-7887	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_046471336.1	31	MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5147;MetaCyc: PWY-8047;MetaCyc: PWY-5366;MetaCyc: PWY-5971;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-7663;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-8049;MetaCyc: PWY-7664;MetaCyc: PWY-5367;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-7858;MetaCyc: PWY-5994	"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"";"Mupirocin biosynthesis";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)"
XP_046475170.1	4	KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_046490800.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046490313.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_046472455.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-174437	"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand"
XP_046476505.1	19	Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-428543;Reactome: R-HSA-8950505;Reactome: R-HSA-5625970;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-4420097	"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate KTN1";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"EGFR downregulation";"GPVI-mediated activation cascade";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"Myogenesis";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway"
XP_046473367.1	7	KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791	"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis I";"Drug metabolism - other enzymes";"UMP biosynthesis III"
XP_046485937.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_046486464.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046478128.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046478770.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_046466744.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_046466297.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046467651.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178	"Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions";"ECM proteoglycans"
XP_046484884.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046470936.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-6802952	"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions"
XP_046477306.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046474505.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046478429.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046488819.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046467103.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046474189.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046465998.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046489143.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046490624.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046484973.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046473713.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046475551.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046479108.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046489878.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_046479280.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046487193.1	4	Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-983168	"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046492257.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_046469234.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Purine metabolism"
XP_046474762.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046471315.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046483474.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_046464783.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046485635.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046466453.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_046488135.1	6	MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_046478217.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_046468532.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046489136.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046467715.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046491584.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046480417.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046464930.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_046471175.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046483588.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046473132.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex"
XP_046469286.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046467162.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046488000.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046468578.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046466301.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046489709.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046471670.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046473461.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046488099.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_046483973.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_046467816.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046484918.1	29	Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape"
XP_046467238.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_046473145.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046470821.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167290	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation"
XP_046470208.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046491563.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046483261.1	4	KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17	"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis"
XP_046472362.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046483429.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_046485430.1	22	MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-7036;MetaCyc: PWY-7726;MetaCyc: PWY-7725;MetaCyc: PWY-6958;KEGG: 00062+4.2.1.134;Reactome: R-HSA-75876;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7053;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_046468203.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046485256.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046479749.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046467481.1	11	KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-5685938;Reactome: R-HSA-5663213	"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)";"RHO GTPases Activate WASPs and WAVEs"
XP_046492660.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046469063.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046481390.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046490866.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046467689.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_046468644.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046467334.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046478339.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046488633.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046482694.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_046472229.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046490190.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046482496.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046477390.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_046493382.1	10	Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_046472135.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046485958.1	7	Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_046490027.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046482225.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046474769.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046479159.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046470768.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046482290.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046475554.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046476821.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046466379.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase"
XP_046487269.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122	"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046477988.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_046475643.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046477344.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046469465.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046467936.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046484446.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_046484176.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046478823.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_046489686.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_046469578.1	8	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046469092.1	16	Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884	"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX"
XP_046479296.1	7	MetaCyc: PWY-5941;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6737	"Glycogen degradation II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V"
XP_046466013.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046470282.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046491480.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046468365.1	13	MetaCyc: PWY-7112;MetaCyc: PWY-4061;Reactome: R-HSA-196836;Reactome: R-HSA-156590;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450"
XP_046478224.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046480686.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046490374.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167290	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation"
XP_046490309.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046473469.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046477939.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_046480437.1	10	Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756	"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_046477283.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158	"Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V"
XP_046487524.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_046465911.1	5	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_046493098.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046482306.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046477024.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046490138.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046487933.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046481208.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_046480721.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046481828.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046482235.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691	"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling"
XP_046491306.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046490339.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046484980.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046474806.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046469373.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046469751.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046482287.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046483262.1	4	Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_046476851.1	6	Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;MetaCyc: PWY-6987	"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_046488039.1	13	Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-177504	"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"VLDLR internalisation and degradation";"Recycling pathway of L1";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling"
XP_046478514.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046468909.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_046492726.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046492624.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046480673.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046484492.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046484885.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_046472794.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046470770.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046479507.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046465189.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046475769.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PA";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Synthesis of PG";"Ether lipid metabolism"
XP_046476745.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_046477348.1	5	Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046466642.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046490653.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046472462.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046470231.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046490848.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046474941.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046493172.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046491636.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046486161.1	5	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_046483736.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046483703.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_046486039.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046479160.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046491463.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046477957.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046473302.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046492034.1	57	Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-349425	"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_046490093.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046477579.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Metalloprotease DUBs"
XP_046481389.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046466361.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_046468665.1	15	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-5696394;Reactome: R-HSA-72689;Reactome: R-HSA-5689603;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"DNA Damage Recognition in GG-NER";"Formation of a pool of free 40S subunits";"UCH proteinases";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046465095.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_046479747.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046490414.1	3	Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90	"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_046465229.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046489034.1	4	MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849;MetaCyc: PWY-7394	"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin II"
XP_046489854.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046480367.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046475814.1	10	KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6886;Reactome: R-HSA-70263;Reactome: R-HSA-70171	"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis"
XP_046481996.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046466010.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism"
XP_046475872.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046476066.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation"
XP_046485287.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_046472891.1	14	Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803	"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046477013.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_046491778.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046469731.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046491832.1	13	MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_046476006.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_046490628.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_046472304.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046488676.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_046474645.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_046467193.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046465144.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III"
XP_046474839.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_046479080.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046477518.1	19	MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-5913;Reactome: R-HSA-75105;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8	"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Reductive TCA cycle II";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes"
XP_046475384.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-438066	"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"RAF activation";"Long-term potentiation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_046479660.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046469406.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046479556.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046476495.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046482632.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046486115.1	29	Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046471310.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046477331.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046471905.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046493096.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046466120.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046493322.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_046465618.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046481979.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046483426.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_046474703.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046481978.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046484493.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046469028.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046482633.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046491962.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046482207.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046491110.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046468882.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046469184.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_046466374.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_046483962.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046469157.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631	"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility"
XP_046473087.1	12	MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-1861;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13	"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Gluconeogenesis";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway"
XP_046467575.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046490320.1	8	Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690	"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"HCMV Early Events"
XP_046486905.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_046476634.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_046484871.1	7	MetaCyc: PWY-882;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456	"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation"
XP_046480208.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046481661.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_046484201.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046465529.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046486863.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046470485.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046490164.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046486770.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046480416.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_046465651.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046473256.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046492665.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046489480.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046484165.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046472223.1	8	Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9609736	"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors"
XP_046469300.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-110381;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_046474649.1	7	Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-373080	"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Activation of SMO";"Class B/2 (Secretin family receptors)"
XP_046473076.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_046467286.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046481958.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046480392.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046491141.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046478123.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046480964.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046484713.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046467422.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046492128.1	6	Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_046484457.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046469857.1	7	Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_046476531.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046471608.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids"
XP_046479492.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046492577.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046465542.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_046489585.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046473780.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046485427.1	27	Reactome: R-HSA-6807505;Reactome: R-HSA-73856;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-9010553;Reactome: R-HSA-191859;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-159231;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975956;Reactome: R-HSA-113418;Reactome: R-HSA-77588;Reactome: R-HSA-77595	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Termination";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"snRNP Assembly";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the Early Elongation Complex";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Intronless Pre-mRNAs"
XP_046466837.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046492682.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy"
XP_046474632.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382	"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex"
XP_046485514.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211976	"Xenobiotics";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Endogenous sterols"
XP_046469040.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046492399.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_046480053.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046482048.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-9609690	"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Viral Messenger RNA Synthesis";"HCMV Early Events"
XP_046474178.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046483925.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565	"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_046473956.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046474908.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation"
XP_046479392.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046481023.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214	"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins"
XP_046468483.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046483191.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046475798.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046489702.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_046470081.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046475589.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-192823	"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Viral mRNA Translation"
XP_046480318.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046489663.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046476439.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046486661.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046486571.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046466076.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046475723.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor"
XP_046485133.1	57	Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-195253	"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex"
XP_046464916.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046483776.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046479918.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046489298.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_046480007.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046483905.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046465521.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046486450.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_046479554.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_046481268.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046464983.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_046481631.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046465078.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_046479290.1	24	Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_046487887.1	10	Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761	"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_046480054.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046492408.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046472717.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046476438.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046467708.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046489601.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046489889.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_046489473.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046473436.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877	"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Gap junction assembly";"Cilium Assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase"
XP_046481056.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046470565.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046482456.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_046486465.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046482943.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_046482624.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_046487052.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046464735.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046475722.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592	"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_046491106.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046489503.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046486046.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046479281.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046469297.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046482413.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_046478811.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046490418.1	3	Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90	"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_046484842.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_046483246.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_046482429.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_046472965.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046466467.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046466628.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046474017.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_046475117.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046481546.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_046482683.1	17	Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection"
XP_046472902.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046470911.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046464915.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046477623.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Processing of DNA double-strand break ends"
XP_046474344.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046473230.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046486874.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_046469743.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046482168.1	13	Reactome: R-HSA-380972;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920	"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"mTOR signalling";"Macroautophagy";"PIP3 activates AKT signaling";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability"
XP_046478090.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046471246.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_046480482.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046466577.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_046488585.1	8	Reactome: R-HSA-418889;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Caspase activation via Dependence Receptors in the absence of ligand";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046469006.1	16	MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7218;Reactome: R-HSA-70263;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-5484	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)"
XP_046490156.1	13	MetaCyc: PWY-2161;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3;KEGG: 00720+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757	"Folate polyglutamylation";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations I";"Folate transformations II (plants)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Metabolism of folate and pterines"
XP_046476685.1	4	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_046477058.1	42	Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-912446;Reactome: R-HSA-3214841;Reactome: R-HSA-3214815;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-1221632;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-5334118;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-9610379;Reactome: R-HSA-9616222;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-212300;Reactome: R-HSA-110328;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-4551638;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-2299718	"HCMV Early Events";"RMTs methylate histone arginines";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic recombination";"PKMTs methylate histone lysines";"HDACs deacetylate histones";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Meiotic synapsis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"DNA methylation";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"HCMV Late Events";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"SUMOylation of chromatin organization proteins";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"Condensation of Prophase Chromosomes"
XP_046478276.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_046467904.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046475443.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_046492797.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_046481595.1	10	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239	"mTOR signaling pathway";"Relaxin signaling pathway";"RSK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"PI3K-Akt signaling pathway";"Recycling pathway of L1"
XP_046488642.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046481534.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046473287.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938	"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)"
XP_046473253.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046485017.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046475744.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046486541.1	26	Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-5617472;Reactome: R-HSA-9614657;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-210744	"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FOXO-mediated transcription of cell death genes";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_046493091.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_046470476.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046472390.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046467006.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_046473103.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046480321.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046465070.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046469004.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_046491416.1	11	Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-72163;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2173796	"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"mRNA Splicing - Major Pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_046492830.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046483336.1	5	Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling"
XP_046477341.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046475928.1	11	Reactome: R-HSA-114604;Reactome: R-HSA-391160;Reactome: R-HSA-877312;Reactome: R-HSA-389948;Reactome: R-HSA-9008059;Reactome: R-HSA-210990;Reactome: R-HSA-388841;Reactome: R-HSA-432142;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-912694	"GPVI-mediated activation cascade";"Signal regulatory protein family interactions";"Regulation of IFNG signaling";"PD-1 signaling";"Interleukin-37 signaling";"PECAM1 interactions";"Costimulation by the CD28 family";"Platelet sensitization by LDL";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling"
XP_046471875.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046475233.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046472723.1	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_046476674.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_046479065.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046482942.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046489361.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046482818.1	9	Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-5627083;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-9646399;Reactome: R-HSA-8856825	"Late endosomal microautophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RHO GTPases regulate CFTR trafficking";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis"
XP_046473035.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046470121.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_046479939.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_046484642.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046477132.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046469345.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046476559.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_046486404.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046466659.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046470436.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046481078.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_046470236.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046489455.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046486319.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_046472645.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046476853.1	6	MetaCyc: PWY-6987;Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism"
XP_046475879.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046475019.1	14	Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-399997;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-418217;Reactome: R-HSA-434316;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-500657;KEGG: 00562+3.1.4.11	"G alpha (q) signalling events";"Ca2+ pathway";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Acetylcholine regulates insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G beta:gamma signalling through PLC beta";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Presynaptic function of Kainate receptors";"Inositol phosphate metabolism"
XP_046488252.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046488658.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046486562.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944	"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2"
XP_046489685.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport"
XP_046484282.1	9	Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167290	"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation"
XP_046470261.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046475869.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_046471083.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046470445.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046464919.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046474174.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046475412.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324	"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Long-term potentiation";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"RAF activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046480104.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046479575.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046476196.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046483825.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_046477434.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046487034.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046487422.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046488538.1	8	Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-5099900	"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4"
XP_046476241.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046472339.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046486891.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873;MetaCyc: PWY-7233	"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
XP_046473571.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046480470.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_046483282.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046486132.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046475405.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046470509.1	10	Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;Reactome: R-HSA-975634;MetaCyc: PWY-5691;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;Reactome: R-HSA-977225;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;MetaCyc: PWY-7394	"Retinoid cycle disease events";"Neutrophil degranulation";"Retinoid metabolism and transport";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Purine metabolism";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II"
XP_046491066.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_046465874.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_046481829.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046476733.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_046468033.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_046477002.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_046469381.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046480494.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_046465179.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046489927.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046485428.1	22	MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7726;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_046477956.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046479705.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046487640.1	6	MetaCyc: PWY-6309;MetaCyc: PWY-5651;MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;Reactome: R-HSA-71240	"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan catabolism"
XP_046472410.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046472918.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046476587.1	18	MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Anandamide biosynthesis I"
XP_046482951.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_046474835.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046476346.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046469520.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046466897.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_046466653.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_046465326.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046480971.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046484511.1	9	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046467927.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046485251.1	6	Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122	"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis"
XP_046482386.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HCMV Early Events"
XP_046472136.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046466708.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_046470465.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046481956.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046486772.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046465061.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_046476037.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046466514.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046473334.1	6	MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation"
XP_046469482.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_046465653.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046483440.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046479557.1	6	KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221	"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_046491271.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046489150.1	8	KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_046482226.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046481981.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046473781.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046484583.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046487459.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_046466129.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046469094.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046475556.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046484813.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Choline catabolism";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046492150.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046478434.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046480892.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046482857.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046467214.1	4	Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_046484839.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046487569.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_046469093.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence"
XP_046467459.1	5	Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_046490529.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_046486033.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046483304.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046482140.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-168333	"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_046471619.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046473876.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68689	"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex"
XP_046472380.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046466367.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_046470232.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046491786.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046469660.1	6	MetaCyc: PWY-6737;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-5941	"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation III";"Sucrose biosynthesis II";"Glycogen degradation II"
XP_046482794.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_046491113.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046487650.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046473330.1	6	KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism"
XP_046467324.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046473919.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046490401.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_046474888.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_046482193.1	20	Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756	"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation"
XP_046485254.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046470181.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046472733.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400	"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_046479323.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046465562.1	4	Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046467350.1	4	Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-975871	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane"
XP_046490908.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046482578.1	10	MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis"
XP_046491280.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_046477053.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046484255.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_046467152.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_046481190.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_046473174.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046489340.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046483873.1	6	Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-381426	"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_046470508.1	10	Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-2453864;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;MetaCyc: PWY-7849	"Amyloid fiber formation";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Retinoid cycle disease events";"Retinoid metabolism and transport";"Neutrophil degranulation";"Urate conversion to allantoin I";"Urate conversion to allantoin III"
XP_046482681.1	17	Reactome: R-HSA-6783310;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607	"Fanconi Anemia Pathway";"Human papillomavirus infection";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends"
XP_046478878.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046481214.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_046468963.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562	"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)"
XP_046478517.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046478258.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046479927.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046484835.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046484491.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046481973.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_046491434.1	6	MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism"
XP_046469014.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_046482669.1	5	Reactome: R-HSA-168638;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"NOD1/2 Signaling Pathway";"DSCAM interactions";"mTOR signaling pathway";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
XP_046482227.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046484014.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046465148.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046483948.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_046475053.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046477727.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046466410.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046491302.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_046489789.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046473269.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046478856.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046489701.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_046474440.1	18	MetaCyc: PWY-8086;MetaCyc: PWY-1622;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7115	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methane metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_046489515.1	6	KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_046477576.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046468045.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046466843.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046491098.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046474907.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046468922.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046471555.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046479561.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046492644.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046471302.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046488396.1	5	KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane"
XP_046487511.1	39	Reactome: R-HSA-5654704;Reactome: R-HSA-5654689;Reactome: R-HSA-5654695;Reactome: R-HSA-5654219;Reactome: R-HSA-5654221;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-2219530;Reactome: R-HSA-2033514;Reactome: R-HSA-190375;Reactome: R-HSA-5654228;Reactome: R-HSA-5658623;Reactome: R-HSA-109704;Reactome: R-HSA-5654687;Reactome: R-HSA-2033519;Reactome: R-HSA-5654732;Reactome: R-HSA-5654710;Reactome: R-HSA-190371;Reactome: R-HSA-5654712;Reactome: R-HSA-5655253;Reactome: R-HSA-5654699;Reactome: R-HSA-1839122;Reactome: R-HSA-190322;Reactome: R-HSA-5654693;Reactome: R-HSA-5654726;Reactome: R-HSA-5673001;Reactome: R-HSA-5654733;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5654688;Reactome: R-HSA-190372;Reactome: R-HSA-1839130;Reactome: R-HSA-5654719;Reactome: R-HSA-5654720;Reactome: R-HSA-8853338;Reactome: R-HSA-5654727;Reactome: R-HSA-5655302;Reactome: R-HSA-5654227;Reactome: R-HSA-190373	"SHC-mediated cascade:FGFR3";"PI-3K cascade:FGFR1";"PI-3K cascade:FGFR2";"Phospholipase C-mediated cascade: FGFR1";"Phospholipase C-mediated cascade, FGFR2";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"FGFR3 mutant receptor activation";"FGFR2c ligand binding and activation";"Phospholipase C-mediated cascade, FGFR4";"FGFRL1 modulation of FGFR1 signaling";"PI3K Cascade";"Downstream signaling of activated FGFR1";"Activated point mutants of FGFR2";"Negative regulation of FGFR3 signaling";"PI-3K cascade:FGFR3";"FGFR3b ligand binding and activation";"FRS-mediated FGFR4 signaling";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR2";"Signaling by activated point mutants of FGFR1";"FGFR4 ligand binding and activation";"FRS-mediated FGFR1 signaling";"Negative regulation of FGFR1 signaling";"RAF/MAP kinase cascade";"Negative regulation of FGFR4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"SHC-mediated cascade:FGFR1";"FGFR3c ligand binding and activation";"Signaling by activated point mutants of FGFR3";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR4";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR2 signaling";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade, FGFR3";"FGFR1c ligand binding and activation"
XP_046465779.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046489481.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046466644.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046472940.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RMTs methylate histone arginines"
XP_046489094.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046479006.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046489723.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046479491.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046466893.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_046479279.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046487357.1	5	MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171	"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis"
XP_046468542.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046477882.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046473291.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046464855.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_046487155.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046485219.1	6	KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807	"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_046487645.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046485960.1	7	Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-198323;Reactome: R-HSA-165181	"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB"
XP_046487617.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046489304.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_046487184.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046479510.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046473435.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025	"RHO GTPases activate IQGAPs";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Cilium Assembly";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation"
XP_046489215.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_046470676.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046488117.1	5	Reactome: R-HSA-111469;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111463	"SMAC, XIAP-regulated apoptotic response";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs"
XP_046474633.1	16	Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-167200;Reactome: R-HSA-180585	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G"
XP_046474625.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_046464863.1	42	MetaCyc: PWY-7726;MetaCyc: PWY-5177;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5109;MetaCyc: PWY-7094;MetaCyc: PWY-7216;KEGG: 00360+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7779;MetaCyc: PWY-7606;MetaCyc: PWY-7654;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-6944;MetaCyc: PWY-6946;MetaCyc: PWY-5138;MetaCyc: PWY-7007;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-5789;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5136	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"Geraniol degradation";"Propanoate metabolism";"Benzoate degradation";"Toluene degradation";"Spodoptera littoralis pheromone biosynthesis";"Fermentation to 2-methylbutanoate";"Fatty acid salvage";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Phenylalanine metabolism";"Tryptophan metabolism";"Pyruvate fermentation to hexanol (engineered)";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation";"Pyruvate fermentation to butanol II (engineered)";"Methyl tert-butyl ether degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"alpha-Linolenic acid metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Androstenedione degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl ketone biosynthesis (engineered)";"Caprolactam degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Lysine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Butanoate metabolism";"beta-Alanine metabolism";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol I";"Butanoate metabolism";"2-methylpropene degradation";"Aminobenzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_046480237.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046487003.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046475653.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_046467687.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046469759.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046488062.1	14	KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5078;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5108;MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-7767;KEGG: 00966+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5076	"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"L-isoleucine degradation II";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis II";"L-leucine degradation IV (Stickland reaction)";"Glucosinolate biosynthesis";"Pantothenate and CoA biosynthesis";"L-valine degradation II";"L-leucine degradation III"
XP_046473952.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046466698.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_046464877.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046478032.1	5	MetaCyc: PWY-5046;Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4	"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism"
XP_046475549.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046472958.1	7	MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_046475004.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_046464967.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_046475793.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046480671.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046486318.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_046471449.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046484399.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046468466.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046477322.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046491752.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046480094.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046487466.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046474895.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_046476956.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046483581.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046491843.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046474334.1	4	Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes"
XP_046478324.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5578749	"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs"
XP_046484872.1	7	Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456	"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation"
XP_046485616.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046476100.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046489712.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046471880.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046489671.1	5	KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6122	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_046478998.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046477463.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046493396.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046477041.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046488910.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046472416.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"RORA activates gene expression";"snRNP Assembly";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046474588.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046479025.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_046477848.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046476004.1	6	MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-6364	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_046487214.1	19	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-8876725;Reactome: R-HSA-3214858;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Protein methylation";"RMTs methylate histone arginines";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs"
XP_046487810.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046489355.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046464920.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046485563.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046479019.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046478578.1	15	Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5689896;Reactome: R-HSA-111465	"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins"
XP_046469151.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046489203.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046466385.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046476398.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046492593.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046466582.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046491596.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046474820.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-9031525;Reactome: R-HSA-8866427	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation"
XP_046466773.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046473216.1	14	MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7782	"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis"
XP_046471872.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046469998.1	4	MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20	"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism"
XP_046480099.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046491514.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046465479.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046481660.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046478315.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046474836.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046485640.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046488006.1	6	KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10	"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_046486162.1	5	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_046489800.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046485995.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046479774.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046469052.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046465160.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111459	"Formation of apoptosome";"Regulation of the apoptosome activity";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage"
XP_046479457.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_046469367.1	10	MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Galactose metabolism"
XP_046466121.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046479373.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046472933.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722	"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex"
XP_046480988.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_046470570.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046486064.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046479665.1	6	MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_046489785.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046487954.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046466788.1	12	Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840	"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"DCC mediated attractive signaling";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle"
XP_046466543.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046479991.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046472305.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046465983.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046478044.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046468298.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046484832.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398	"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway"
XP_046470374.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046478516.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046475702.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_046471528.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-201688	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL"
XP_046491314.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046466289.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046477151.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046467181.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_046467903.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046492051.1	10	Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"D-galactose detoxification";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis"
XP_046488703.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046488740.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_046483263.1	4	Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_046474977.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046465161.1	10	Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_046465066.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046465041.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_046491653.1	30	Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-2564830;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-112382	"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex"
XP_046492476.1	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_046482197.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046466005.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046470896.1	5	MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism"
XP_046486456.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046474938.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046484937.1	7	Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-212436;Reactome: R-HSA-2173796	"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_046473316.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046477991.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433	"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046487984.1	9	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol"
XP_046482286.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046486774.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046477102.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046474865.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046471409.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046471584.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046478660.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046475633.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046474530.1	3	KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262;MetaCyc: PWY-6100	"Lysine degradation";"Carnitine synthesis";"L-carnitine biosynthesis"
XP_046486572.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046464869.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046475832.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046466176.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046469996.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046474008.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046484241.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046493163.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046492727.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046469382.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046464913.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046482010.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_046488194.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046491383.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_046477472.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046476472.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046486662.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046478256.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046486564.1	15	Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity"
XP_046479209.1	7	Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046484334.1	20	MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-5136	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_046487589.1	26	Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497	"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"Gap junction assembly";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_046469630.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046475192.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046469073.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046486565.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459	"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046486778.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046473570.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_046465588.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046482788.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_046465224.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046468459.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046486413.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046480065.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046486314.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_046484912.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046490184.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046471271.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_046488826.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046491561.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046487552.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722	"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046484881.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046491201.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046488693.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046469100.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN"
XP_046476322.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046465432.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046470133.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_046482970.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_046481213.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046485084.1	11	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097	"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_046486559.1	15	Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408	"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation"
XP_046484352.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_046478930.1	4	KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_046466731.1	8	MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086	"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_046474477.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046476650.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046490336.1	42	MetaCyc: PWY-6583;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-5136;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-5138;MetaCyc: PWY-7007;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00903+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-6883;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7779;MetaCyc: PWY-6944;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6435;MetaCyc: PWY-7726;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-5109;MetaCyc: PWY-7656;KEGG: 00623+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35	"Pyruvate fermentation to butanol I";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"2-methylpropene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Caprolactam degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid degradation";"beta-Alanine metabolism";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Limonene and pinene degradation";"Benzoyl-coa degradation I (aerobic)";"Tryptophan metabolism";"Pyruvate fermentation to hexanol (engineered)";"Phenylalanine metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl tert-butyl ether degradation";"Androstenedione degradation";"alpha-Linolenic acid metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Geraniol degradation";"Glutaryl-coa degradation";"Propanoate metabolism";"Fatty acid salvage";"Fermentation to 2-methylbutanoate";"Spodoptera littoralis pheromone biosynthesis";"Toluene degradation";"Benzoate degradation"
XP_046490759.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046470090.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046469238.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Purine metabolism"
XP_046479473.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"FOXO-mediated transcription of cell death genes";"Relaxin signaling pathway";"mTOR signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_046480253.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046478806.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046474169.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046466817.1	4	MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603	"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine"
XP_046470844.1	10	Reactome: R-HSA-4719377;MetaCyc: PWY-7979;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719360;Reactome: R-HSA-913709;MetaCyc: PWY-7922;Reactome: R-HSA-162699;MetaCyc: PWY-7921;MetaCyc: PWY-7661;Reactome: R-HSA-4717374	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation III (mammals, core M3)";"N-Glycan biosynthesis";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"O-linked glycosylation of mucins";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_046475629.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046482615.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046468564.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046491711.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_046484686.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046491919.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046464716.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046472145.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046488116.1	5	Reactome: R-HSA-111469;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-111464	"SMAC, XIAP-regulated apoptotic response";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_046469768.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046471888.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_046488594.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046469030.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046480095.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046476920.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046474898.1	9	Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046468628.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046484922.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046466492.1	17	Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-5357956;Reactome: R-HSA-1169091;Reactome: R-HSA-975163;Reactome: R-HSA-5689880	"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TNFR1-induced NFkappaB signaling pathway";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases"
XP_046469469.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046486475.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-193681;Reactome: R-HSA-5626978	"Glycosphingolipid metabolism";"Ceramide signalling";"TNFR1-mediated ceramide production"
XP_046490158.1	13	MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613	"Folate transformations I";"Folate transformations II (plants)";"Folate polyglutamylation";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"One carbon pool by folate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_046471082.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046490845.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046475286.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046470773.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046485684.1	6	MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3322077	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_046472939.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243	"Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046482084.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046490086.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046466910.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046472308.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046481184.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-6842	"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II"
XP_046490120.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046479961.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046478871.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_046477231.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_046483435.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046477742.1	13	KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-71403	"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)"
XP_046492495.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046489892.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046482635.1	13	Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-1660662	"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism"
XP_046465177.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046469182.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_046465677.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046473948.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046468550.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046473332.1	6	KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23	"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation"
XP_046481656.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046473538.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046474942.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046467128.1	8	Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Signaling by Hippo";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046465657.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046469216.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046485936.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046478104.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046464813.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_046486467.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046475809.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_046474437.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046489812.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046479220.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046481619.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046491367.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046469412.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046487259.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046477753.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046487821.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046469159.1	11	Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling"
XP_046469229.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_046472719.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046478178.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046471206.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"Viral mRNA Translation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_046470679.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046478297.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046479321.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046489787.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046475763.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_046477514.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels"
XP_046466000.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046492045.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_046474335.1	4	KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_046465731.1	4	KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_046482285.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046487204.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_046470937.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802946	"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants"
XP_046470326.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046491464.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046486270.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_046465533.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046470829.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046474610.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046482766.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_046472221.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_046481506.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_046469215.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046478102.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046476469.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046484246.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046489820.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046470372.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046485439.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046481683.1	16	KEGG: 00020+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5749;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.4	"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Itaconate degradation";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism"
XP_046486640.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_046469798.1	11	Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948	"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_046487762.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046484024.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_046482739.1	5	Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
XP_046476948.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046486577.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046486220.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046476355.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046475940.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046486093.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs"
XP_046492070.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046467806.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046467930.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046484944.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046489753.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046486575.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046467202.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_046475581.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046464778.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046483904.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046466929.1	9	Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-1362277;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Transcription of E2F targets under negative control by DREAM complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex"
XP_046465631.1	5	MetaCyc: PWY-6168;MetaCyc: PWY-5523;Reactome: R-HSA-196843;MetaCyc: PWY-7863;KEGG: 00740+2.7.1.26	"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"Riboflavin metabolism"
XP_046486041.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046478432.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046489368.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046469114.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046479172.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_046468559.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046470994.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046487872.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176412	"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C"
XP_046476759.1	3	Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_046482415.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_046469236.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040	"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_046477886.1	9	Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"UCH proteinases"
XP_046473034.1	26	Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877	"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"Cilium Assembly";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase"
XP_046480322.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046469343.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046480130.1	14	Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-1474228;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-193692;Reactome: R-HSA-2979096	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Degradation of the extracellular matrix";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_046474863.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046465401.1	4	MetaCyc: PWY-6030;KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931	"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis"
XP_046475071.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-4641263;Reactome: R-HSA-4608870;Reactome: R-HSA-5340588;Reactome: R-HSA-4086398;Reactome: R-HSA-8856828;Reactome: R-HSA-373080;Reactome: R-HSA-5099900	"Cargo recognition for clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Asymmetric localization of PCP proteins";"RNF mutants show enhanced WNT signaling and proliferation";"Ca2+ pathway";"Clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"WNT5A-dependent internalization of FZD4"
XP_046474913.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046481889.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046465530.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046486468.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046473240.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046475941.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046481823.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046475760.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_046490426.1	3	Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90	"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_046493118.1	2	KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697	"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_046482627.1	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_046485020.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046488650.1	4	KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046464782.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046483026.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation"
XP_046474514.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_046469118.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046491779.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046489010.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046470544.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046478303.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046472677.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Cilium Assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins"
XP_046467331.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046470002.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046466436.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046466853.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046477627.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046470329.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046477139.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046471241.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046487722.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_046490906.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046477982.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_046470302.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_046487388.1	5	KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism"
XP_046468995.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046483826.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046479519.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8852276	"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_046470876.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_046465124.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_046473214.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_046472415.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"snRNP Assembly";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression"
XP_046481869.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046466173.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046473902.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046475009.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046484011.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046488232.1	11	Reactome: R-HSA-5668599;Reactome: R-HSA-1660516;Reactome: R-HSA-1632852;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-1660517;Reactome: R-HSA-109704;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514	"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the early endosome membrane";"Macroautophagy";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the late endosome membrane";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane"
XP_046492952.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046477840.1	24	Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_046474436.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046480527.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814	"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes"
XP_046472894.1	14	MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport"
XP_046484018.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046492552.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_046482854.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046479431.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046471558.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046485268.1	9	Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69183	"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Processive synthesis on the lagging strand"
XP_046469108.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046464845.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_046483058.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046471700.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-420029;Reactome: R-HSA-2173791	"Asymmetric localization of PCP proteins";"Tight junction interactions";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_046479622.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046474188.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046481961.1	12	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5628897	"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"TP53 Regulates Metabolic Genes"
XP_046491529.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046478987.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046490870.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046477317.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046479973.1	8	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_046492792.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046466455.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046488286.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046466421.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046484892.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046470973.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046465198.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046467858.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_046478017.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_046481146.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_046467164.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046480715.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046467378.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway"
XP_046474976.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046485804.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046480414.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046477916.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046476996.1	42	Reactome: R-HSA-5693565;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-2299718;Reactome: R-HSA-110330;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-9616222;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-212300;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-1912408;Reactome: R-HSA-5334118;Reactome: R-HSA-5578749;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-3214847;Reactome: R-HSA-3214841;Reactome: R-HSA-3214815;Reactome: R-HSA-69473;Reactome: R-HSA-606279;Reactome: R-HSA-912446	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected purine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"Transcriptional regulation of granulopoiesis";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PRC2 methylates histones and DNA";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Oxidative Stress Induced Senescence";"Meiotic synapsis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"Pre-NOTCH Transcription and Translation";"DNA methylation";"Transcriptional regulation by small RNAs";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"HCMV Early Events";"HATs acetylate histones";"PKMTs methylate histone lysines";"HDACs deacetylate histones";"G2/M DNA damage checkpoint";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic recombination"
XP_046482304.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046466322.1	26	Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69205;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-8866654;Reactome: R-HSA-5656121;Reactome: R-HSA-174437;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-6804114;Reactome: R-HSA-4615885;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-1362277;Reactome: R-HSA-110312;Reactome: R-HSA-69091	"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"G1/S-Specific Transcription";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion synthesis by POLI";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SUMOylation of DNA replication proteins";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by REV1";"Polymerase switching"
XP_046472759.1	13	MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_046490457.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4	"Selenocompound metabolism";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Assimilatory sulfate reduction III";"Purine metabolism";"Selenate reduction";"Monobactam biosynthesis";"Sulfur metabolism";"Transport and synthesis of PAPS";"Purine metabolism"
XP_046488537.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-196025	"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions"
XP_046483335.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128	"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling"
XP_046481878.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_046476790.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046469013.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046475526.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046472186.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_046489336.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046483498.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_046479002.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046464929.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_046469941.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046469312.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_046490098.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046488908.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046486325.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_046482281.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046478251.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046480374.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046478893.1	33	Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159231	"snRNP Assembly";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046479026.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_046477715.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_046479262.1	18	Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4	"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Linoleic acid metabolism"
XP_046480836.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046471780.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046483894.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046478931.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_046479255.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091	"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching"
XP_046488586.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_046467701.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046472841.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046486453.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046487129.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046478630.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469	"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis"
XP_046490958.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046478603.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5689896;Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716	"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_046486750.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046488529.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_046479947.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_046484206.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046469362.1	10	MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11	"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism"
XP_046466896.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_046470229.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046467544.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046471568.1	11	MetaCyc: PWY-6607;Reactome: R-HSA-8851680;MetaCyc: PWY-6538;MetaCyc: PWY-5695;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-6999;Reactome: R-HSA-74259;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6608	"Guanosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Theophylline degradation";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation III"
XP_046470693.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046472758.1	13	MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_046465173.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046479659.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046486006.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046489792.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046492290.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_046486912.1	3	KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046468456.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046485074.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046468003.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046469595.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046474685.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046483990.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_046479605.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046470228.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046476640.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046486056.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046475749.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046491457.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046490135.1	9	MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;Reactome: R-HSA-1474151;MetaCyc: PWY-6147	"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I"
XP_046486527.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046479868.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046469576.1	8	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046465676.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046474367.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_046477490.1	33	Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-69202;Reactome: R-HSA-6782135;Reactome: R-HSA-69656;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Cyclin E associated events during G1/S transition";"Dual incision in TC-NER";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_046470083.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046488673.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046477547.1	6	MetaCyc: PWY-5789;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5743	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate cycle"
XP_046488911.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046475569.1	7	MetaCyc: PWY-7782;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-3385;Reactome: R-HSA-1483213	"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Synthesis of PE"
XP_046481267.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046490545.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046476522.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046486303.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_046487662.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046488952.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_046479656.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046466802.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046493187.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression"
XP_046488569.1	5	Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation"
XP_046487791.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_046465902.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046468580.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046482790.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046465277.1	3	Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_046481254.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_046478742.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046467633.1	17	Reactome: R-HSA-6804114;Reactome: R-HSA-2559580;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-69231;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1912408;Reactome: R-HSA-69205;Reactome: R-HSA-111448;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-9616222;Reactome: R-HSA-8953750;Reactome: R-HSA-2559585;Reactome: R-HSA-113501	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Oxidative Stress Induced Senescence";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"Cyclin D associated events in G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Pre-NOTCH Transcription and Translation";"G1/S-Specific Transcription";"Activation of NOXA and translocation to mitochondria";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of granulopoiesis";"Transcriptional Regulation by E2F6";"Oncogene Induced Senescence";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_046486026.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046488311.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046478043.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046486532.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046465274.1	3	Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_046475386.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046492357.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046489895.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046476676.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046466931.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046487290.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046490631.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046491916.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_046476301.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046469590.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046491487.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046487631.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046480876.1	5	MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;Reactome: R-HSA-6798695	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation"
XP_046467287.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046491310.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046483843.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation"
XP_046475361.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046466002.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046490889.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046465501.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046488521.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046475415.1	4	KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50	"Arginine and proline metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_046476440.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046476832.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046474928.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046478740.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046484837.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046483189.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046491446.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_046479352.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046489516.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis"