Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
OTAU011047-PA	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
OTAU008100-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU012472-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU007465-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
OTAU007250-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
OTAU004159-PA	7	Reactome: R-HSA-71403;KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064	"Citric acid cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine catabolism"
OTAU009277-PA	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
OTAU007370-PA	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
OTAU016977-PA	26	Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-210744	"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
OTAU012010-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU003892-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU010006-PA	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
OTAU013755-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
OTAU006265-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU009085-PA	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
OTAU015277-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU009958-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU016209-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
OTAU004884-PA	14	MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080	"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I"
OTAU009307-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
OTAU002134-PA	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU008087-PA	26	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Kinesins";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
OTAU009756-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU012855-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU001977-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU002333-PA	1	Reactome: R-HSA-70350	"Fructose catabolism"
OTAU001045-PA	3	MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581	"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
OTAU001831-PA	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism"
OTAU011771-PA	5	Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-381038;Reactome: R-HSA-5358346;MetaCyc: PWY-7511	"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis";"Protein ubiquitination"
OTAU005291-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
OTAU012858-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU000333-PA	9	MetaCyc: PWY-6611;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;Reactome: R-HSA-983168;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1	"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine metabolism";"Adenine and adenosine salvage III";"Antigen processing: Ubiquitination & Proteasome degradation";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation II"
OTAU012395-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
OTAU002663-PA	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
OTAU008826-PA	5	KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3	"Pyrimidine metabolism";"Pyrimidine catabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes"
OTAU008173-PA	5	Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025	"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions"
OTAU001118-PA	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
OTAU000143-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU011484-PA	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
OTAU003385-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU011894-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
OTAU017038-PA	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
OTAU014822-PA	17	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 04714+2.7.11.1;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-174178;Reactome: R-HSA-5663220;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9022692	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"PI3K-Akt signaling pathway";"EML4 and NUDC in mitotic spindle formation";"Thermogenesis";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RHO GTPases Activate Formins";"Human immunodeficiency virus 1 infection";"Regulation of MECP2 expression and activity"
OTAU003370-PA	6	Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation"
OTAU003015-PA	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
OTAU008015-PA	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
OTAU001197-PA	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
OTAU006737-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
OTAU009238-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
OTAU009169-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
OTAU013132-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU015537-PA	3	Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
OTAU007542-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
OTAU014494-PA	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
OTAU002688-PA	9	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
OTAU000415-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU007462-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU003522-PA	3	Reactome: R-HSA-72764;Reactome: R-HSA-156581;Reactome: R-HSA-432722	"Eukaryotic Translation Termination";"Methylation";"Golgi Associated Vesicle Biogenesis"
OTAU001951-PA	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69202	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin E associated events during G1/S transition"
OTAU006364-PA	31	MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWY-7858;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-6519;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-7663;MetaCyc: PWY-8047;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-6113;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7723;MetaCyc: PWY-5147;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7664;Reactome: R-HSA-75105;MetaCyc: PWY-7388;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5971;MetaCyc: PWY-8012;MetaCyc: PWY-5367	"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bacterial bioluminescence";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acyl-CoA biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Petroselinate biosynthesis"
OTAU013189-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
OTAU005917-PA	13	KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857	"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation"
OTAU002833-PA	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
OTAU002070-PA	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
OTAU009154-PA	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
OTAU012259-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU000920-PA	24	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs"
OTAU008764-PA	7	KEGG: 00270+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22	"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism"
OTAU006799-PA	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
OTAU016086-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
OTAU000596-PA	8	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Ion channel transport";"Photosynthesis";"Insulin receptor recycling";"ATP biosynthesis";"Amino acids regulate mTORC1"
OTAU012913-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
OTAU009686-PA	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
OTAU013043-PA	16	Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-112382;Reactome: R-HSA-8951664	"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of RNA Pol II elongation complex";"Neddylation"
OTAU002050-PA	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
OTAU016305-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU001792-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU000800-PA	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
OTAU001075-PA	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
OTAU014444-PA	10	MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-6842	"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II"
OTAU000346-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
OTAU017457-PA	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
OTAU017266-PA	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
OTAU000194-PA	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
OTAU009623-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
OTAU005346-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU003739-PA	6	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-975957	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU002831-PA	20	MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7574;Reactome: R-HSA-9033241	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Peroxisomal protein import"
OTAU007131-PA	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
OTAU010128-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU016062-PA	4	Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU001742-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
OTAU014073-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
OTAU007311-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU012003-PA	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
OTAU001364-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
OTAU010557-PA	27	Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-191859	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly"
OTAU014359-PA	5	KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64	"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
OTAU014183-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU004103-PA	13	KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662	"Other glycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism"
OTAU014056-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
OTAU013849-PA	4	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
OTAU017094-PA	3	Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Complex I biogenesis"
OTAU000619-PA	20	MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7858;Reactome: R-HSA-2564830;MetaCyc: PWY-7726	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Cytosolic iron-sulfur cluster assembly";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
OTAU009835-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
OTAU015930-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
OTAU000833-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU014582-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU016530-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU006988-PA	7	KEGG: 00520+3.5.99.6;Reactome: R-HSA-71336;MetaCyc: PWY-6855;MetaCyc: PWY-6906;MetaCyc: PWY-8004;MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31	"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway"
OTAU005888-PA	57	Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276	"UCH proteinases";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Hedgehog 'on' state";"Neutrophil degranulation";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint"
OTAU014561-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU002861-PA	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
OTAU004569-PA	6	MetaCyc: PWY-5941;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6731	"Glycogen degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation III"
OTAU003392-PA	1	Reactome: R-HSA-8964572	"Lipid particle organization"
OTAU008113-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU009855-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU002022-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU014273-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
OTAU015903-PA	12	Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"NRAGE signals death through JNK";"Rho GTPase cycle";"mTOR signaling pathway";"Relaxin signaling pathway";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Thermogenesis"
OTAU005589-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU006991-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU000690-PA	3	MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5	"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
OTAU003482-PA	3	KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
OTAU000989-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
OTAU000524-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
OTAU016466-PA	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
OTAU008588-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU015334-PA	8	Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091	"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching"
OTAU001436-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU003891-PA	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
OTAU003138-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
OTAU008592-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU016273-PA	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
OTAU013213-PA	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
OTAU000790-PA	5	Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis"
OTAU003903-PA	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
OTAU000454-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
OTAU000062-PA	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
OTAU007375-PA	5	Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
OTAU015071-PA	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
OTAU016151-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU002439-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU007722-PA	32	Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-168325;Reactome: R-HSA-76042	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
OTAU008105-PA	8	Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Signaling by Hippo";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
OTAU014681-PA	7	Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"Cyclin D associated events in G1";"G1/S-Specific Transcription";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
OTAU011021-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
OTAU001586-PA	12	MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00670+2.1.2.9;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6613;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.2;Reactome: R-HSA-196780;Reactome: R-HSA-73817;KEGG: 00230+6.3.3.1;KEGG: 00230+6.3.4.13	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"One carbon pool by folate";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Purine metabolism"
OTAU000766-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU004296-PA	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
OTAU010014-PA	1	Reactome: R-HSA-977443	"GABA receptor activation"
OTAU000124-PA	13	Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-8948216;Reactome: R-HSA-2214320;Reactome: R-HSA-419037	"ECM proteoglycans";"Extracellular matrix organization";"Signaling by PDGF";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"Collagen chain trimerization";"Anchoring fibril formation";"NCAM1 interactions"
OTAU000589-PA	18	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7221	"Drug metabolism - other enzymes";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis"
OTAU002142-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU011700-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU007897-PA	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
OTAU016004-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU005413-PA	11	Reactome: R-HSA-3214858;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114	"RMTs methylate histone arginines";"RORA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
OTAU006107-PA	7	MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
OTAU012080-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
OTAU005768-PA	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
OTAU010433-PA	6	KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism"
OTAU011386-PA	4	MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
OTAU001485-PA	7	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
OTAU005138-PA	6	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
OTAU003609-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
OTAU001917-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
OTAU014385-PA	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
OTAU014255-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU001835-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
OTAU001407-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU005550-PA	8	Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209	"Macroautophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
OTAU008431-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU005984-PA	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
OTAU013126-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU008463-PA	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
OTAU007611-PA	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
OTAU006060-PA	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
OTAU005284-PA	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1362277	"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex"
OTAU006647-PA	8	Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-164378	"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling"
OTAU016052-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU011582-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
OTAU008846-PA	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
OTAU012421-PA	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
OTAU001525-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
OTAU002290-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU010657-PA	8	MetaCyc: PWY-5651;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733;MetaCyc: PWY-7765;MetaCyc: PWY-7734;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-6309	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Quinoxaline-2-carboxylate biosynthesis";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)"
OTAU013121-PA	18	KEGG: 00360+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1	"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism"
OTAU008736-PA	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
OTAU007496-PA	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
OTAU007992-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
OTAU000855-PA	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
OTAU014364-PA	14	Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569	"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
OTAU000023-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU007364-PA	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
OTAU014398-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
OTAU013231-PA	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation"
OTAU003375-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU013772-PA	7	KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;MetaCyc: PWY-6471;KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265;Reactome: R-HSA-4549356;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
OTAU008176-PA	5	Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
OTAU008886-PA	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
OTAU009825-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU004916-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU005366-PA	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
OTAU013612-PA	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
OTAU012521-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU010369-PA	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
OTAU007203-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU001761-PA	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
OTAU012538-PA	26	Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-389977	"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway"
OTAU011393-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU012437-PA	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
OTAU008175-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU008499-PA	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
OTAU002626-PA	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
OTAU005354-PA	7	Reactome: R-HSA-1474151;MetaCyc: PWY-6614;MetaCyc: PWY-3841;Reactome: R-HSA-69205;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate biosynthesis"
OTAU015641-PA	8	MetaCyc: PWY-6372;MetaCyc: PWY-6580;MetaCyc: PWY-4661;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis"
OTAU008861-PA	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
OTAU016610-PA	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
OTAU013234-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
OTAU004962-PA	7	Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5358346	"Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog ligand biogenesis"
OTAU007093-PA	31	MetaCyc: PWY-6113;MetaCyc: PWY-5994;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7723;MetaCyc: PWY-7664;MetaCyc: PWY-5147;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-7388;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-5989;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-8047;MetaCyc: PWY-6799;MetaCyc: PWY-8049;MetaCyc: PWYG-321	"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bacterial bioluminescence";"Oleate biosynthesis IV (anaerobic)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"Mupirocin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Pederin biosynthesis";""
OTAU010285-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
OTAU015978-PA	19	MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-735	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis"
OTAU000514-PA	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
OTAU011976-PA	2	Reactome: R-HSA-75094;Reactome: R-HSA-72200	"Formation of the Editosome";"mRNA Editing: C to U Conversion"
OTAU012545-PA	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
OTAU016986-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU015209-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
OTAU007501-PA	56	Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780	"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome"
OTAU010275-PA	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
OTAU000655-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
OTAU005114-PA	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
OTAU007030-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
OTAU014107-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU013642-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU015261-PA	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
OTAU001456-PA	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
OTAU004744-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
OTAU008630-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU005819-PA	1	MetaCyc: PWY-7379	"Mrna capping II"
OTAU014817-PA	7	MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5469	"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis"
OTAU008782-PA	5	Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122	"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
OTAU013041-PA	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
OTAU006689-PA	27	Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-168325	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"HCMV Early Events";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis"
OTAU005610-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU000096-PA	1	Reactome: R-HSA-1483166	"Synthesis of PA"
OTAU010126-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU014240-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU005707-PA	4	Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism"
OTAU004216-PA	25	Reactome: R-HSA-8939256;Reactome: R-HSA-8939246;Reactome: R-HSA-8941332;Reactome: R-HSA-8941284;Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-8878166;Reactome: R-HSA-8931987;Reactome: R-HSA-8877330;Reactome: R-HSA-8936459;Reactome: R-HSA-8941858;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247;Reactome: R-HSA-8951936;Reactome: R-HSA-8940973;Reactome: R-HSA-8941326;Reactome: R-HSA-8951911;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-8941333;Reactome: R-HSA-8935964;Reactome: R-HSA-8939902;Reactome: R-HSA-8939245	"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates chondrocyte maturation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Transcriptional regulation by RUNX2";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX3 expression and activity";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 regulates p14-ARF";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates bone development";"RUNX3 regulates RUNX1-mediated transcription";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates expression of components of tight junctions";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in BCR signaling"
OTAU008446-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
OTAU007174-PA	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
OTAU002280-PA	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
OTAU009602-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU002933-PA	57	Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5689603	"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Hedgehog 'on' state";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"UCH proteinases"
OTAU013272-PA	31	MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-6113;MetaCyc: PWY-5994;MetaCyc: PWY-5142;MetaCyc: PWY-5367;MetaCyc: PWY-7388;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-5971;MetaCyc: PWY-8012;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5147;MetaCyc: PWY-7664;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;MetaCyc: PWY-4381;MetaCyc: PWY-6519;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-7746;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-6799;MetaCyc: PWY-7663;MetaCyc: PWY-8047	"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Biotin metabolism";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis"
OTAU005303-PA	13	MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969	"Reductive TCA cycle II";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
OTAU001643-PA	18	MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482925	"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG"
OTAU002314-PA	11	KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654	"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Thermogenesis";"Cytosolic sensors of pathogen-associated DNA";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins"
OTAU003240-PA	4	MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+3.2.1.114;KEGG: 00513+3.2.1.114	"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
OTAU004865-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU000780-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU015265-PA	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
OTAU016603-PA	10	Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
OTAU005593-PA	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
OTAU006352-PA	22	MetaCyc: PWY-5384;MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-8013;KEGG: 00030+5.3.1.9;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6981;MetaCyc: PWY-7347;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.9;MetaCyc: PWY-622;Reactome: R-HSA-70263;MetaCyc: PWY-621;MetaCyc: PWY-5659;MetaCyc: PWY-7385;MetaCyc: PWY-5054;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-3801;Reactome: R-HSA-5628897	"Sucrose degradation IV (sucrose phosphorylase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Pentose phosphate pathway";"Starch and sucrose metabolism";"Chitin biosynthesis";"Sucrose biosynthesis III";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Starch biosynthesis";"Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"GDP-mannose biosynthesis";"1,3-propanediol biosynthesis (engineered)";"D-sorbitol biosynthesis I";"Sucrose biosynthesis II";"Neutrophil degranulation";"Sucrose degradation II (sucrose synthase)";"TP53 Regulates Metabolic Genes"
OTAU008559-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU009776-PA	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
OTAU013847-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
OTAU005034-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU004009-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
OTAU003466-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
OTAU003289-PA	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
OTAU010961-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
OTAU000973-PA	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
OTAU000516-PA	9	KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52	"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
OTAU008744-PA	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU012959-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU006276-PA	27	Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107	"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"HCMV Early Events";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
OTAU010872-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU008000-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU012150-PA	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
OTAU008004-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU004137-PA	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion"
OTAU016851-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU002263-PA	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
OTAU008005-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU001065-PA	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
OTAU008190-PA	24	Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU016383-PA	16	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Translation initiation complex formation"
OTAU000876-PA	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
OTAU009838-PA	10	Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
OTAU002921-PA	4	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
OTAU014027-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU010455-PA	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
OTAU005969-PA	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes"
OTAU001409-PA	1	Reactome: R-HSA-5578775	"Ion homeostasis"
OTAU002948-PA	6	Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801	"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair"
OTAU013679-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU011926-PA	27	Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-168271	"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus"
OTAU003262-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
OTAU002725-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
OTAU000786-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU012108-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU001918-PA	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
OTAU004375-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU010418-PA	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
OTAU016046-PA	1	Reactome: R-HSA-1483148	"Synthesis of PG"
OTAU003884-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
OTAU014239-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU000118-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
OTAU008093-PA	14	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2022377;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Metabolism of Angiotensinogen to Angiotensins";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
OTAU000378-PA	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-189200	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"Cellular hexose transport"
OTAU005978-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU007740-PA	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
OTAU004577-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
OTAU000639-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
OTAU002949-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU003059-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU010166-PA	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
OTAU001595-PA	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826	"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis"
OTAU001317-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU004831-PA	13	MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-561	"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation"
OTAU011271-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
OTAU000654-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
OTAU006739-PA	11	Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152	"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat"
OTAU016937-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
OTAU017314-PA	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
OTAU006108-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU003979-PA	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6433;Reactome: R-HSA-75876	"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs"
OTAU006019-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
OTAU002977-PA	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
OTAU011053-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
OTAU008230-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU014275-PA	5	Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
OTAU005627-PA	1	Reactome: R-HSA-186797	"Signaling by PDGF"
OTAU003549-PA	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
OTAU009062-PA	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
OTAU003791-PA	9	Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368108	"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
OTAU017092-PA	3	Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-6799198	"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Complex I biogenesis"
OTAU003596-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU004079-PA	7	Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
OTAU012494-PA	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
OTAU000590-PA	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
OTAU009478-PA	7	KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-7625;MetaCyc: PWY-6351;Reactome: R-HSA-1483226	"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI"
OTAU013268-PA	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
OTAU000986-PA	4	MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
OTAU014739-PA	4	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis"
OTAU001623-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
OTAU010552-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
OTAU004828-PA	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241	"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import"
OTAU006406-PA	7	KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation"
OTAU016544-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU009595-PA	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
OTAU011151-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU014147-PA	57	Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813	"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids"
OTAU015626-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU007425-PA	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473	"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint"
OTAU007353-PA	5	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
OTAU001901-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
OTAU000562-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
OTAU004646-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU000652-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
OTAU010833-PA	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
OTAU012157-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU015726-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU006920-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU007657-PA	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
OTAU004908-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU016623-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
OTAU010661-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU013823-PA	2	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
OTAU009164-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU001785-PA	4	Reactome: R-HSA-72163;Reactome: R-HSA-2393930;Reactome: R-HSA-72165;MetaCyc: PWY-6502	"mRNA Splicing - Major Pathway";"Phosphate bond hydrolysis by NUDT proteins";"mRNA Splicing - Minor Pathway";"8-oxo-(d)GTP detoxification I"
OTAU014489-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
OTAU008879-PA	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
OTAU001203-PA	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
OTAU005149-PA	1	Reactome: R-HSA-373753	"Nephrin family interactions"
OTAU007110-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
OTAU005351-PA	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
OTAU002850-PA	5	Reactome: R-HSA-2562578;Reactome: R-HSA-1810476;Reactome: R-HSA-9013957;Reactome: R-HSA-168927;Reactome: R-HSA-937041	"TRIF-mediated programmed cell death";"RIP-mediated NFkB activation via ZBP1";"TLR3-mediated TICAM1-dependent programmed cell death";"TICAM1, RIP1-mediated IKK complex recruitment";"IKK complex recruitment mediated by RIP1"
OTAU015621-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU012268-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU005091-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU007390-PA	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
OTAU016216-PA	7	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
OTAU003699-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
OTAU003827-PA	16	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
OTAU015906-PA	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
OTAU017309-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
OTAU003353-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU013459-PA	11	Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation"
OTAU011059-PA	12	MetaCyc: PWY-5870;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5872	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
OTAU010974-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
OTAU003692-PA	18	KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-7383;MetaCyc: PWY-5392;Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561	"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation"
OTAU015878-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU015535-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU001571-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
OTAU008152-PA	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-6796648	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes"
OTAU011728-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
OTAU014157-PA	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
OTAU008847-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
OTAU005198-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU007243-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
OTAU012941-PA	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
OTAU008547-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU006881-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU011224-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU001600-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
OTAU003286-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU003993-PA	8	Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress"
OTAU009452-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU003583-PA	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression"
OTAU001979-PA	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
OTAU001947-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU010954-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
OTAU012665-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU003278-PA	6	Reactome: R-HSA-74259;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-5497	"Purine catabolism";"Guanosine nucleotides degradation II";"Purine metabolism";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)"
OTAU001292-PA	4	Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis"
OTAU013461-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU010930-PA	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829	"Aggrephagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy"
OTAU006007-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU016094-PA	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
OTAU012418-PA	10	MetaCyc: PWY-7979;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7661;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;KEGG: 00510+2.4.1.83;Reactome: R-HSA-162699;Reactome: R-HSA-913709	"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate mannose";"O-linked glycosylation of mucins"
OTAU001258-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU002942-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
OTAU005452-PA	4	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-2132295;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"MHC class II antigen presentation";"Mitochondrial translation elongation"
OTAU008172-PA	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
OTAU010632-PA	12	Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167243	"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery"
OTAU011461-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU005210-PA	26	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
OTAU004524-PA	16	Reactome: R-HSA-166058;Reactome: R-HSA-3134963;Reactome: R-HSA-5602680;Reactome: R-HSA-209543;Reactome: R-HSA-5602498;Reactome: R-HSA-975110;Reactome: R-HSA-5603037;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-1257604;Reactome: R-HSA-9020702;Reactome: R-HSA-5603041;Reactome: R-HSA-975155;Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-1810476	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 deficiency (TLR5)";"p75NTR recruits signalling complexes";"MyD88 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"Interleukin-1 signaling";"IRAK4 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"RIP-mediated NFkB activation via ZBP1"
OTAU002188-PA	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
OTAU002438-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU002340-PA	1	Reactome: R-HSA-70350	"Fructose catabolism"
OTAU000613-PA	13	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription"
OTAU014996-PA	5	Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780	"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome"
OTAU004417-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU010137-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
OTAU008811-PA	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
OTAU000362-PA	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
OTAU005577-PA	16	Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
OTAU014374-PA	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
OTAU015182-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
OTAU003394-PA	56	Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684	"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state"
OTAU007559-PA	13	KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-7384;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5537	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Methylaspartate cycle";"Pyruvate fermentation to acetate V"
OTAU009830-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
OTAU004374-PA	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
OTAU016559-PA	8	MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-7524	"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)"
OTAU001514-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
OTAU007493-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU001695-PA	9	Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-5484	"Gluconeogenesis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)"
OTAU003133-PA	13	KEGG: 00982+2.5.1.18;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-7112	"Drug metabolism - cytochrome P450";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification"
OTAU001786-PA	7	Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Macroautophagy"
OTAU011382-PA	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
OTAU012242-PA	56	Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590	"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Degradation of AXIN";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling"
OTAU013428-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
OTAU000671-PA	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU001174-PA	16	Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174178	"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
OTAU006625-PA	15	Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938	"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)"
OTAU011436-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
OTAU010511-PA	1	Reactome: R-HSA-70263	"Gluconeogenesis"
OTAU007640-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU001294-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
OTAU005280-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
OTAU001321-PA	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
OTAU008208-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU001565-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU002200-PA	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
OTAU000760-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
OTAU016160-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA"
OTAU000179-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU002714-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
OTAU006867-PA	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
OTAU012051-PA	26	Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320	"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes"
OTAU005285-PA	27	Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3301854	"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly"
OTAU001200-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
OTAU005235-PA	12	MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-7230	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
OTAU002182-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
OTAU005893-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU009649-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
OTAU004761-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU014037-PA	7	Reactome: R-HSA-5689880;Reactome: R-HSA-171319;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-606279;Reactome: R-HSA-5689603;Reactome: R-HSA-201722	"Ub-specific processing proteases";"Telomere Extension By Telomerase";"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere";"UCH proteinases";"Formation of the beta-catenin:TCF transactivating complex"
OTAU007917-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU009610-PA	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
OTAU011460-PA	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
OTAU004090-PA	7	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation"
OTAU000853-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU016662-PA	2	Reactome: R-HSA-75094;Reactome: R-HSA-72200	"Formation of the Editosome";"mRNA Editing: C to U Conversion"
OTAU011866-PA	7	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-389960	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC"
OTAU003756-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU000217-PA	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I"
OTAU003980-PA	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
OTAU001519-PA	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
OTAU007533-PA	13	Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5687128;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Rho GTPase cycle";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"G alpha (q) signalling events";"Relaxin signaling pathway";"mTOR signaling pathway";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"MAPK6/MAPK4 signaling";"Thermogenesis";"PI3K-Akt signaling pathway"
OTAU000979-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU002554-PA	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
OTAU005231-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
OTAU003531-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU002827-PA	4	Reactome: R-HSA-912631;Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656	"Regulation of signaling by CBL";"Downstream signal transduction";"MET activates RAP1 and RAC1";"MET receptor recycling"
OTAU007538-PA	12	Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Sulfite oxidation III";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Selenate reduction";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism"
OTAU001953-PA	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
OTAU009932-PA	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation"
OTAU006760-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU012714-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
OTAU008303-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU001398-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
OTAU016883-PA	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
OTAU005531-PA	56	Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-4641257	"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"Degradation of AXIN"
OTAU009757-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
OTAU012011-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU009459-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU009189-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
OTAU001410-PA	13	Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-1489509	"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling"
OTAU008828-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU013455-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
OTAU003872-PA	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
OTAU013858-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
OTAU011799-PA	9	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"mTOR signalling";"Amino acids regulate mTORC1"
OTAU009123-PA	4	KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16	"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism"
OTAU016457-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU017062-PA	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
OTAU005654-PA	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6	"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism"
OTAU007761-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU001073-PA	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
OTAU009795-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU003490-PA	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
OTAU006700-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU008071-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
OTAU007251-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU013380-PA	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
OTAU000470-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU012579-PA	1	Reactome: R-HSA-525793	"Myogenesis"
OTAU001801-PA	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
OTAU005982-PA	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
OTAU010253-PA	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
OTAU006578-PA	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
OTAU002852-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU003069-PA	11	KEGG: 00480+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-7268;MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7124	"Glutathione metabolism";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Ethylene biosynthesis V (engineered)"
OTAU000460-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU007253-PA	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
OTAU000420-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
OTAU008101-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU009887-PA	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
OTAU009550-PA	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
OTAU002373-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
OTAU007550-PA	6	MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560	"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerophospholipid metabolism";"Triglyceride catabolism"
OTAU010151-PA	2	Reactome: R-HSA-2132295;Reactome: R-HSA-5620922	"MHC class II antigen presentation";"BBSome-mediated cargo-targeting to cilium"
OTAU014019-PA	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
OTAU013325-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU006699-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
OTAU012084-PA	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
OTAU013875-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
OTAU012854-PA	5	KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
OTAU000001-PA	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
OTAU002302-PA	4	Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852	"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy"
OTAU002795-PA	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
OTAU011741-PA	5	Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
OTAU010688-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU002978-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU000440-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU012486-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU001864-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU017226-PA	16	Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript"
OTAU002679-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
OTAU003559-PA	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
OTAU010314-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU003166-PA	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
OTAU012764-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
OTAU013732-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
OTAU008767-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
OTAU007786-PA	10	MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-3841;Reactome: R-HSA-69205;MetaCyc: PWY-7199;MetaCyc: PWY-7198;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
OTAU002857-PA	4	Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-166058	"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
OTAU006405-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU014442-PA	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
OTAU013106-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU007031-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
OTAU006629-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
OTAU007261-PA	24	Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Kinesins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
OTAU000526-PA	8	Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"HCMV Early Events";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
OTAU001826-PA	20	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange"
OTAU009012-PA	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
OTAU008884-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
OTAU010205-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
OTAU005474-PA	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
OTAU007404-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU000743-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU008490-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU003793-PA	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
OTAU000447-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU008049-PA	1	Reactome: R-HSA-3295583	"TRP channels"
OTAU006217-PA	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
OTAU006266-PA	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
OTAU004527-PA	3	KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
OTAU015129-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
OTAU005884-PA	8	MetaCyc: PWY-7979;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
OTAU011263-PA	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
OTAU000731-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
OTAU007534-PA	12	Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Rho GTPase cycle";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"G alpha (q) signalling events";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"PI3K-Akt signaling pathway";"Thermogenesis"
OTAU008127-PA	15	MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40	"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Purine metabolism"
OTAU010334-PA	30	Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-69231;Reactome: R-HSA-2894862;Reactome: R-HSA-8939902;Reactome: R-HSA-1170546;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-2644607;Reactome: R-HSA-174113;Reactome: R-HSA-2565942	"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"Prolactin receptor signaling";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition"
OTAU014410-PA	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
OTAU002715-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
OTAU007454-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU006271-PA	18	Reactome: R-HSA-8941855;Reactome: R-HSA-69895;Reactome: R-HSA-6785807;Reactome: R-HSA-2559586;Reactome: R-HSA-69231;Reactome: R-HSA-8852276;Reactome: R-HSA-5674400;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-198323;Reactome: R-HSA-69563;Reactome: R-HSA-8866911;Reactome: R-HSA-6804116;Reactome: R-HSA-9617828;Reactome: R-HSA-187577;Reactome: R-HSA-69202;Reactome: R-HSA-8878166;Reactome: R-HSA-69656	"RUNX3 regulates CDKN1A transcription";"Transcriptional activation of cell cycle inhibitor p21";"Interleukin-4 and Interleukin-13 signaling";"DNA Damage/Telomere Stress Induced Senescence";"Cyclin D associated events in G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Constitutive Signaling by AKT1 E17K in Cancer";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"AKT phosphorylates targets in the cytosol";"p53-Dependent G1 DNA Damage Response";"TFAP2 (AP-2) family regulates transcription of cell cycle factors";"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest";"FOXO-mediated transcription of cell cycle genes";"SCF(Skp2)-mediated degradation of p27/p21";"Cyclin E associated events during G1/S transition";"Transcriptional regulation by RUNX2";"Cyclin A:Cdk2-associated events at S phase entry"
OTAU014958-PA	2	Reactome: R-HSA-352230;Reactome: R-HSA-442660	"Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters"
OTAU012013-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU006228-PA	12	Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
OTAU008759-PA	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
OTAU004840-PA	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates"
OTAU014745-PA	13	MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
OTAU005236-PA	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
OTAU011012-PA	9	MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16	"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Folate biosynthesis"
OTAU007332-PA	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
OTAU013811-PA	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
OTAU011278-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU007834-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU009242-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU003007-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
OTAU001790-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU014733-PA	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
OTAU005275-PA	8	Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208	"mTOR signalling";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling"
OTAU016366-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU009010-PA	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
OTAU014200-PA	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
OTAU013715-PA	14	Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
OTAU003150-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU001612-PA	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
OTAU005401-PA	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
OTAU002922-PA	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
OTAU000620-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU005643-PA	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
OTAU000569-PA	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism"
OTAU007237-PA	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
OTAU015813-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU004650-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU010691-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU013038-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU016590-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU012767-PA	17	MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes"
OTAU007340-PA	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
OTAU015875-PA	5	Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
OTAU008251-PA	15	Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-9603505;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243	"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"NTRK3 as a dependence receptor";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery"
OTAU003475-PA	33	Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-69231;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-69202;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin D associated events in G1";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
OTAU016013-PA	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
OTAU010769-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
OTAU006288-PA	5	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005	"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport"
OTAU013275-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU017308-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU008311-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
OTAU016386-PA	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
OTAU006620-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU000571-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU002510-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU005528-PA	6	Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol"
OTAU004320-PA	18	Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"mTORC1-mediated signalling";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU012082-PA	14	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2500257;Reactome: R-HSA-380259;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-8854518;Reactome: R-HSA-428890;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-141444	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Resolution of Sister Chromatid Cohesion";"Loss of Nlp from mitotic centrosomes";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"AURKA Activation by TPX2";"Role of ABL in ROBO-SLIT signaling";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
OTAU016536-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
OTAU015848-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU012786-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
OTAU001175-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
OTAU005872-PA	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
OTAU002732-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
OTAU005975-PA	10	MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-5484	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)"
OTAU000575-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU000180-PA	6	Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-73933	"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)"
OTAU009448-PA	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
OTAU003718-PA	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
OTAU002964-PA	7	MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522	"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism"
OTAU000522-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU009506-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU000353-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU005027-PA	4	Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
OTAU000356-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU009975-PA	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
OTAU009399-PA	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)"
OTAU003390-PA	10	MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587	"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)"
OTAU004346-PA	8	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
OTAU000086-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
OTAU007403-PA	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
OTAU005723-PA	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
OTAU014758-PA	7	KEGG: 00710+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11	"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism"
OTAU012978-PA	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation"
OTAU002872-PA	10	Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins"
OTAU003854-PA	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
OTAU015361-PA	4	MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism"
OTAU012340-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
OTAU002824-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
OTAU006908-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
OTAU001105-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU010061-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU002709-PA	17	Reactome: R-HSA-139915;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-111448;Reactome: R-HSA-9616222;Reactome: R-HSA-2559585;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-113501;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-2559580;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-6804114	"Activation of PUMA and translocation to mitochondria";"Cyclin D associated events in G1";"G0 and Early G1";"Activation of NOXA and translocation to mitochondria";"Transcriptional regulation of granulopoiesis";"Oncogene Induced Senescence";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Oxidative Stress Induced Senescence";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
OTAU008160-PA	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
OTAU009648-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
OTAU005676-PA	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
OTAU011462-PA	9	Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER"
OTAU016868-PA	5	Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex"
OTAU014083-PA	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389	"Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases"
OTAU001884-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU001555-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU015863-PA	19	Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9649948	"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Long-term potentiation";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants"
OTAU008667-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
OTAU000225-PA	6	Reactome: R-HSA-373080;Reactome: R-HSA-4641262;Reactome: R-HSA-5140745;Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-201681	"Class B/2 (Secretin family receptors)";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Asymmetric localization of PCP proteins";"Ca2+ pathway";"TCF dependent signaling in response to WNT"
OTAU010281-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
OTAU013373-PA	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
OTAU004125-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
OTAU001893-PA	5	KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6	"Purine metabolism";"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism"
OTAU003111-PA	3	Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation"
OTAU007199-PA	18	Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167242	"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat"
OTAU017301-PA	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
OTAU005565-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU000507-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
OTAU002384-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU012135-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
OTAU006103-PA	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
OTAU002165-PA	9	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
OTAU001764-PA	57	Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837	"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"Hedgehog 'on' state";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation"
OTAU014318-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU005907-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU004885-PA	14	MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II"
OTAU004886-PA	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis"
OTAU005992-PA	31	MetaCyc: PWY-7858;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-8047;MetaCyc: PWY-7663;MetaCyc: PWY-6799;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-5994;MetaCyc: PWY-6113;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-7388;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-7664	"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"Mupirocin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)"
OTAU011302-PA	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
OTAU003116-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU000812-PA	2	Reactome: R-HSA-606279;Reactome: R-HSA-2022377	"Deposition of new CENPA-containing nucleosomes at the centromere";"Metabolism of Angiotensinogen to Angiotensins"
OTAU005926-PA	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
OTAU004481-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU001592-PA	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
OTAU000002-PA	3	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
OTAU005471-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU010880-PA	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
OTAU009046-PA	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
OTAU009342-PA	12	Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU004138-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
OTAU002904-PA	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
OTAU007461-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU013978-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU009640-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU011437-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU011338-PA	14	MetaCyc: PWY-6728;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-5690;MetaCyc: PWY-3781;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105	"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Respiratory electron transport"
OTAU012870-PA	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
OTAU009180-PA	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin"
OTAU006404-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU000634-PA	3	Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078	"GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
OTAU015859-PA	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
OTAU017201-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
OTAU006540-PA	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
OTAU009339-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU006117-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
OTAU003677-PA	4	MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
OTAU009290-PA	5	MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841	"Folate transformations I";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations II (plants)"
OTAU000718-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
OTAU005100-PA	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
OTAU002550-PA	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51	"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism"
OTAU003982-PA	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
OTAU000242-PA	57	Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541	"ABC-family proteins mediated transport";"Degradation of AXIN";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway"
OTAU003868-PA	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
OTAU006960-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
OTAU008346-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
OTAU011119-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU003209-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
OTAU003102-PA	1	Reactome: R-HSA-5676934	"Protein repair"
OTAU001463-PA	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
OTAU009155-PA	12	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes"
OTAU000334-PA	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
OTAU008035-PA	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
OTAU012463-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
OTAU000250-PA	4	Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU007053-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU005253-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU006415-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
OTAU012987-PA	15	Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-8853884	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX"
OTAU008461-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU008247-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU001220-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
OTAU007610-PA	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
OTAU000294-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU001906-PA	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
OTAU009141-PA	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
OTAU001462-PA	9	Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210	"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
OTAU004208-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU007540-PA	5	Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-977225	"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy";"Josephin domain DUBs";"Amyloid fiber formation"
OTAU010038-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
OTAU013667-PA	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
OTAU014106-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU016066-PA	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
OTAU011502-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
OTAU009552-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU016441-PA	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
OTAU007313-PA	9	Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape"
OTAU007975-PA	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
OTAU010324-PA	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
OTAU001649-PA	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
OTAU004294-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU003226-PA	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
OTAU012054-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU004364-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU012604-PA	7	MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052	"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis"
OTAU001342-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU005441-PA	6	KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis"
OTAU000606-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
OTAU008097-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU017135-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
OTAU003038-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU009102-PA	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
OTAU009885-PA	5	Reactome: R-HSA-189451;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
OTAU016174-PA	5	Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism"
OTAU011084-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU005292-PA	11	KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-6607;MetaCyc: PWY-5381;MetaCyc: PWY-7821;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-5695	"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine metabolism";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation"
OTAU001361-PA	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape"
OTAU010506-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU004324-PA	13	MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5	"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism"
OTAU012194-PA	8	Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock"
OTAU016431-PA	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6"
OTAU001454-PA	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
OTAU000265-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU000485-PA	1	Reactome: R-HSA-390651	"Dopamine receptors"
OTAU006378-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
OTAU003644-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU010673-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU008236-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
OTAU006519-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU005935-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
OTAU009007-PA	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
OTAU008182-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
OTAU000095-PA	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
OTAU016755-PA	6	MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Candicidin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
OTAU002028-PA	57	Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276	"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Degradation of AXIN";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint"
OTAU002684-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU004983-PA	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
OTAU009745-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
OTAU000739-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
OTAU002849-PA	1	Reactome: R-HSA-525793	"Myogenesis"
OTAU001009-PA	4	Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-3371453	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Cristae formation";"Regulation of HSF1-mediated heat shock response"
OTAU003812-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU000904-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU000886-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU005786-PA	1	Reactome: R-HSA-8849175	"Threonine catabolism"
OTAU008938-PA	8	Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
OTAU009395-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU000519-PA	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
OTAU000829-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU008112-PA	56	Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-174178	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Degradation of AXIN";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
OTAU000374-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU015170-PA	3	Reactome: R-HSA-8953750;Reactome: R-HSA-73772;Reactome: R-HSA-427389	"Transcriptional Regulation by E2F6";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
OTAU000041-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU009793-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU011266-PA	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
OTAU014311-PA	10	Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Ub-specific processing proteases";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"HATs acetylate histones";"Relaxin signaling pathway";"mTOR signaling pathway"
OTAU008349-PA	24	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU012595-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
OTAU002547-PA	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
OTAU006619-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU002760-PA	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
OTAU012603-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU012222-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
OTAU016338-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU005639-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU006376-PA	10	Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-72649;Reactome: R-HSA-72731;Reactome: R-HSA-382556	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"Translation initiation complex formation";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport"
OTAU002135-PA	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU000748-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU005568-PA	6	Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-381426	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
OTAU011552-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
OTAU003541-PA	4	MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
OTAU007492-PA	6	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5685938	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)"
OTAU003477-PA	14	MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-6453	"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Ether lipid metabolism";"Synthesis of PC";"Stigma estolide biosynthesis"
OTAU002659-PA	16	Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-69017	"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6"
OTAU009697-PA	5	MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
OTAU007172-PA	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
OTAU006097-PA	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
OTAU003604-PA	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
OTAU016035-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
OTAU009481-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
OTAU010909-PA	24	Reactome: R-HSA-400042;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-8964616	"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"G-protein activation";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through CDC42"
OTAU013477-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU004411-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU017394-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU012580-PA	1	Reactome: R-HSA-525793	"Myogenesis"
OTAU006402-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU016693-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
OTAU002261-PA	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
OTAU004016-PA	34	Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-69656;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-69202;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
OTAU013663-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU010280-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
OTAU000600-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
OTAU011381-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU001450-PA	7	MetaCyc: PWY-6596;MetaCyc: PWY-7221;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817	"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
OTAU005212-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU014089-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU013953-PA	2	Reactome: R-HSA-913709;MetaCyc: PWY-7511	"O-linked glycosylation of mucins";"Protein ubiquitination"
OTAU016630-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
OTAU017255-PA	18	KEGG: 00960+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642	"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"(R)-cysteate degradation"
OTAU010952-PA	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
OTAU006145-PA	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
OTAU004038-PA	8	KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901;MetaCyc: PWY-5481	"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate"
OTAU003318-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
OTAU005349-PA	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
OTAU012000-PA	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
OTAU013360-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
OTAU009294-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU001084-PA	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
OTAU001793-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
OTAU001021-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU008541-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU017289-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU005939-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU017437-PA	5	Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
OTAU010832-PA	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
OTAU009340-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU012240-PA	4	KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;Reactome: R-HSA-6807047	"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol"
OTAU004291-PA	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
OTAU002243-PA	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
OTAU012770-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU012333-PA	20	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-69091	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Polymerase switching"
OTAU010566-PA	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
OTAU007842-PA	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
OTAU000772-PA	12	KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4	"Sulfur metabolism";"Sulfite oxidation III";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfate activation for sulfonation";"Selenate reduction";"Selenocompound metabolism"
OTAU009268-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU012664-PA	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
OTAU000115-PA	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
OTAU009868-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU014488-PA	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
OTAU000999-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
OTAU011439-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU017326-PA	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
OTAU002694-PA	57	Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-382556	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Hedgehog 'on' state";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"ABC-family proteins mediated transport"
OTAU003616-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
OTAU012821-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU004097-PA	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
OTAU009886-PA	7	Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-114608	"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation"
OTAU010342-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU006674-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
OTAU010694-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU007062-PA	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
OTAU013119-PA	1	Reactome: R-HSA-3295583	"TRP channels"
OTAU005046-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU011784-PA	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
OTAU017134-PA	19	MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7221;Reactome: R-HSA-380320;MetaCyc: PWY-7197;MetaCyc: PWY-6545	"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Drug metabolism - other enzymes";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
OTAU010912-PA	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
OTAU015186-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
OTAU002166-PA	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
OTAU005062-PA	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
OTAU002743-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
OTAU011885-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU005001-PA	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310	"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway"
OTAU005301-PA	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU009190-PA	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
OTAU002629-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU008464-PA	4	Reactome: R-HSA-5578995;Reactome: R-HSA-156581;KEGG: 00970+6.1.1.9;KEGG: 00983+2.1.1.67	"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Methylation";"Aminoacyl-tRNA biosynthesis";"Drug metabolism - other enzymes"
OTAU011789-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU011273-PA	56	Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-450408	"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
OTAU004379-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU007467-PA	6	Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination"
OTAU011698-PA	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
OTAU000576-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU008624-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU010687-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU003045-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
OTAU015438-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
OTAU012344-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
OTAU005012-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
OTAU002323-PA	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU007551-PA	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
OTAU016463-PA	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
OTAU007507-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU000984-PA	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
OTAU014201-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
OTAU000996-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
OTAU013899-PA	33	Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3108214	"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"HCMV Late Events";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins"
OTAU008882-PA	18	Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053	"Acyl chain remodelling of PI";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Anandamide biosynthesis II"
OTAU015408-PA	12	Reactome: R-HSA-70263;MetaCyc: PWY-1861;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171	"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis"
OTAU016020-PA	10	MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2	"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism"
OTAU006374-PA	24	Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-163359;Reactome: R-HSA-416482	"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events"
OTAU010925-PA	4	KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132	"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
OTAU004297-PA	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
OTAU002530-PA	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
OTAU016444-PA	16	Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
OTAU013887-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU016726-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU005260-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU000015-PA	5	KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937	"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport"
OTAU000701-PA	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
OTAU004166-PA	27	Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-168325	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis"
OTAU006040-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU013010-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
OTAU012937-PA	15	Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569	"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
OTAU016936-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU016813-PA	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU006039-PA	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
OTAU016521-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
OTAU003921-PA	1	Reactome: R-HSA-5334118	"DNA methylation"
OTAU009661-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
OTAU014557-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU001164-PA	5	MetaCyc: PWY-7176;MetaCyc: PWY-7177;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185	"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I"
OTAU012284-PA	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
OTAU003445-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU009997-PA	16	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
OTAU002705-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU011970-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU017238-PA	4	KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;Reactome: R-HSA-6807047	"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol"
OTAU015569-PA	1	Reactome: R-HSA-525793	"Myogenesis"
OTAU006692-PA	6	Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-1655829	"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
OTAU006713-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU009554-PA	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
OTAU004024-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
OTAU001733-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
OTAU010355-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU008741-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU011419-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU003648-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU002054-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU012055-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU007094-PA	5	Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168	"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)"
OTAU002816-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU003422-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
OTAU007701-PA	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
OTAU017275-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
OTAU013590-PA	12	Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation"
OTAU000098-PA	1	Reactome: R-HSA-1483166	"Synthesis of PA"
OTAU008898-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
OTAU009080-PA	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
OTAU003940-PA	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
OTAU009237-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU014586-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU004214-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU002692-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
OTAU007710-PA	4	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
OTAU003221-PA	11	MetaCyc: PWY-6174;MetaCyc: PWY-5123;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-6859;MetaCyc: PWY-7560;Reactome: R-HSA-191273;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-7524;KEGG: 00900+5.3.3.2	"Mevalonate pathway II (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"All-trans-farnesol biosynthesis";"Methylerythritol phosphate pathway II";"Cholesterol biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis"
OTAU013030-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU004599-PA	9	MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1	"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
OTAU012768-PA	17	MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7210	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
OTAU001791-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU007781-PA	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
OTAU013599-PA	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
OTAU001420-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU008820-PA	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
OTAU003397-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
OTAU016814-PA	1	Reactome: R-HSA-5635838	"Activation of SMO"
OTAU003355-PA	4	Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6802952	"Neutrophil degranulation";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions"
OTAU009818-PA	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism"
OTAU016340-PA	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
OTAU006218-PA	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
OTAU014402-PA	8	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-167590	"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation"
OTAU015889-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
OTAU000542-PA	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
OTAU007966-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU006022-PA	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
OTAU007458-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
OTAU014119-PA	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
OTAU003838-PA	9	Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
OTAU004306-PA	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
OTAU009921-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU009346-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
OTAU009980-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU016944-PA	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
OTAU007360-PA	7	MetaCyc: PWY-7185;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;KEGG: 00730+3.6.1.15	"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Thiamine metabolism"
OTAU009894-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
OTAU008968-PA	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
OTAU014580-PA	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
OTAU012166-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
OTAU007646-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
OTAU009045-PA	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
OTAU004503-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
OTAU009876-PA	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
OTAU006829-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
OTAU007686-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU002771-PA	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
OTAU004343-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
OTAU008466-PA	5	Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-211976	"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Phase I - Functionalization of compounds";"Endogenous sterols"
OTAU007196-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
OTAU008524-PA	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
OTAU004926-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
OTAU001085-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU015030-PA	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
OTAU002785-PA	5	Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU003673-PA	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
OTAU011705-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
OTAU015916-PA	56	Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176	"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
OTAU001338-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
OTAU007819-PA	16	Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-176409	"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins"
OTAU002680-PA	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
OTAU001204-PA	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
OTAU015519-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU012532-PA	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
OTAU008250-PA	15	Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-9603505;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152	"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"NTRK3 as a dependence receptor";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat"
OTAU000573-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
OTAU006101-PA	27	Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-3301854	"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly"
OTAU007807-PA	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
OTAU001656-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
OTAU001209-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU004066-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
OTAU017402-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU007450-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
OTAU007200-PA	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
OTAU007252-PA	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
OTAU001181-PA	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
OTAU000566-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
OTAU001664-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU005904-PA	3	Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway"
OTAU005316-PA	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
OTAU016294-PA	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
OTAU014319-PA	4	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
OTAU005979-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU003551-PA	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
OTAU006350-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU016156-PA	3	Reactome: R-HSA-6785631;Reactome: R-HSA-6798695;Reactome: R-HSA-5663220	"ERBB2 Regulates Cell Motility";"Neutrophil degranulation";"RHO GTPases Activate Formins"
OTAU015858-PA	9	MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1	"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism"
OTAU012912-PA	3	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism"
OTAU007833-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU000987-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
OTAU013743-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
OTAU000808-PA	5	KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3	"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage";"Pyrimidine metabolism"
OTAU006613-PA	10	MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7411	"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)"
OTAU009310-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU014109-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU007593-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU003974-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
OTAU000607-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU013619-PA	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
OTAU009687-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU009134-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU000972-PA	7	Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72702	"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition"
OTAU003136-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU014195-PA	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
OTAU015343-PA	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
OTAU001442-PA	7	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation"
OTAU005915-PA	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
OTAU009460-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU014969-PA	14	KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-6901	"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Ethylene biosynthesis V (engineered)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation"
OTAU006051-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU010052-PA	4	Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase"
OTAU007683-PA	6	Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693	"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling"
OTAU014087-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU007426-PA	27	Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-8851708;Reactome: R-HSA-159227;Reactome: R-HSA-72086;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-975956;Reactome: R-HSA-167242;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-111367;Reactome: R-HSA-975957;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-159236;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-159231;Reactome: R-HSA-167152	"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"Signaling by FGFR2 IIIa TM";"Transport of the SLBP independent Mature mRNA";"mRNA Capping";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"SLBP independent Processing of Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of HIV elongation complex in the absence of HIV Tat"
OTAU016754-PA	6	MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-4381;Reactome: R-HSA-196780	"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism"
OTAU002722-PA	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
OTAU008765-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
OTAU011024-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
OTAU008791-PA	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
OTAU008923-PA	57	Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276	"UCH proteinases";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Hedgehog 'on' state";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint"
OTAU005828-PA	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-7279;MetaCyc: PWY-3781	"Oxidative phosphorylation";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)"
OTAU002748-PA	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
OTAU014447-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
OTAU004616-PA	8	Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-6791461	"Pentose phosphate pathway";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"RPIA deficiency: failed conversion of RU5P to R5P"
OTAU004156-PA	7	KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
OTAU012422-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
OTAU017477-PA	14	MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
OTAU001703-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU006642-PA	8	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling by Hippo"
OTAU011721-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
OTAU002273-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU011387-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU005456-PA	7	Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159	"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling"
OTAU011828-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU005629-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
OTAU010831-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU013378-PA	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy"
OTAU014737-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU002986-PA	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
OTAU009514-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU001772-PA	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
OTAU014585-PA	5	Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis"
OTAU000764-PA	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
OTAU008698-PA	8	KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171	"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis"
OTAU015004-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
OTAU013024-PA	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
OTAU005025-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
OTAU001606-PA	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
OTAU012601-PA	16	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU001804-PA	18	MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922	"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI"
OTAU006857-PA	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
OTAU004776-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU015868-PA	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
OTAU003674-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU012313-PA	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
OTAU000109-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
OTAU008228-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU000481-PA	6	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
OTAU013066-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
OTAU013678-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU004082-PA	26	Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Kinesins";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"HCMV Early Events";"Gap junction assembly";"RHO GTPases Activate Formins"
OTAU014483-PA	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
OTAU001478-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU010150-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
OTAU009451-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU016033-PA	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
OTAU001778-PA	7	MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8	"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism"
OTAU001714-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
OTAU008687-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
OTAU004356-PA	8	MetaCyc: PWY-7524;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174	"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)"
OTAU001059-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
OTAU003237-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU003001-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU011807-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
OTAU013102-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
OTAU017267-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU011995-PA	8	Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-196025	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions"
OTAU013728-PA	6	Reactome: R-HSA-3322077;MetaCyc: PWY-622;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18	"Glycogen synthesis";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism"
OTAU002297-PA	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
OTAU005783-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU004512-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU013797-PA	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
OTAU005086-PA	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
OTAU000351-PA	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
OTAU012321-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
OTAU012179-PA	6	Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC"
OTAU000490-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
OTAU011433-PA	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
OTAU009721-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU014128-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
OTAU011049-PA	11	KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;MetaCyc: PWY-6545	"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
OTAU010650-PA	5	Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
OTAU000669-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU005172-PA	5	MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism"
OTAU003117-PA	5	Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972	"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK"
OTAU006318-PA	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
OTAU010508-PA	2	Reactome: R-HSA-418555;Reactome: R-HSA-373080	"G alpha (s) signalling events";"Class B/2 (Secretin family receptors)"
OTAU005220-PA	12	MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187;MetaCyc: PWY-6309;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;Reactome: R-HSA-71240;MetaCyc: PWY-7901	"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine"
OTAU000469-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
OTAU005426-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
OTAU015053-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU005416-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
OTAU008360-PA	5	Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
OTAU003861-PA	10	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-7344	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose catabolism";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis"
OTAU010600-PA	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes"
OTAU007765-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU002557-PA	1	Reactome: R-HSA-1483101	"Synthesis of PS"
OTAU000262-PA	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
OTAU001556-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU006057-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
OTAU002121-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU000411-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
OTAU001334-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU008574-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU003994-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
OTAU002266-PA	8	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"T cell receptor signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway"
OTAU003172-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
OTAU012266-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU006083-PA	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
OTAU008489-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
OTAU000085-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1"
OTAU016625-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU013873-PA	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
OTAU012294-PA	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
OTAU011464-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU005998-PA	9	Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972	"MAP2K and MAPK activation";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
OTAU014874-PA	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
OTAU004182-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
OTAU003859-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
OTAU012312-PA	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation"
OTAU009621-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU012424-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU010327-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
OTAU013134-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU012175-PA	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
OTAU006342-PA	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"PPARA activates gene expression";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
OTAU008699-PA	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
OTAU004513-PA	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
OTAU011625-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA"
OTAU001231-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU010093-PA	56	Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-382556	"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Degradation of AXIN";"ABC-family proteins mediated transport"
OTAU004093-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
OTAU016435-PA	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890	"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling"
OTAU005297-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
OTAU006611-PA	6	Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU008104-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU003204-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU015678-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU012403-PA	26	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"Kinesins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
OTAU007115-PA	32	MetaCyc: PWY-7663;MetaCyc: PWY-6799;MetaCyc: PWY-5989;MetaCyc: PWY-7858;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-8049;MetaCyc: PWYG-321;Reactome: R-HSA-211945;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282	"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Bacterial bioluminescence";"Biotin metabolism";"Mupirocin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Pederin biosynthesis";"";"Phase I - Functionalization of compounds";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)"
OTAU001307-PA	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
OTAU014655-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
OTAU004448-PA	5	MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692	"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation"
OTAU004791-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU003411-PA	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
OTAU003297-PA	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
OTAU007060-PA	2	Reactome: R-HSA-210745;Reactome: R-HSA-210746	"Regulation of gene expression in beta cells";"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"
OTAU004499-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
OTAU000985-PA	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
OTAU003052-PA	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
OTAU004992-PA	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
OTAU007466-PA	7	KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201	"Oxidative phosphorylation";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis"
OTAU002817-PA	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
OTAU011399-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
OTAU002893-PA	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
OTAU005765-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
OTAU010498-PA	57	Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276	"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Degradation of AXIN";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neutrophil degranulation";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint"
OTAU013816-PA	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
OTAU012052-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU000685-PA	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
OTAU016140-PA	26	Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-389977	"Recycling pathway of L1";"Kinesins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway"
OTAU004308-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
OTAU012401-PA	26	Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-389977	"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway"
OTAU009525-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
OTAU006718-PA	4	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis"
OTAU002181-PA	6	MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
OTAU011967-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU017368-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU006151-PA	8	Reactome: R-HSA-163754;Reactome: R-HSA-6791055;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;Reactome: R-HSA-71336	"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway"
OTAU005395-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU002120-PA	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
OTAU005009-PA	29	Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
OTAU007600-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
OTAU006550-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU015429-PA	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
OTAU013686-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
OTAU015042-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
OTAU013239-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU000495-PA	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
OTAU014084-PA	4	MetaCyc: PWY-6030;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4	"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism"
OTAU008354-PA	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
OTAU005215-PA	5	Reactome: R-HSA-1234176;Reactome: R-HSA-8849473;Reactome: R-HSA-8951664;Reactome: R-HSA-1234174;Reactome: R-HSA-1234158	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"PTK6 Expression";"Neddylation";"Cellular response to hypoxia";"Regulation of gene expression by Hypoxia-inducible Factor"
OTAU010083-PA	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
OTAU013735-PA	11	Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1	"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism"
OTAU014859-PA	11	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
OTAU004351-PA	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
OTAU007106-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
OTAU011994-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU001501-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
OTAU002840-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
OTAU008204-PA	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
OTAU013478-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU002582-PA	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
OTAU000626-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU016179-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
OTAU011829-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
OTAU000410-PA	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
OTAU009703-PA	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
OTAU003792-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
OTAU017032-PA	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
OTAU008171-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
OTAU005760-PA	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
OTAU004959-PA	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
OTAU002562-PA	5	KEGG: 00030+4.1.2.4;Reactome: R-HSA-6798695;Reactome: R-HSA-71336;MetaCyc: PWY-7180;MetaCyc: PWY-8060	"Pentose phosphate pathway";"Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I"
OTAU006367-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU004955-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU004664-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
OTAU005113-PA	7	Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-212436	"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway"
OTAU008096-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU010240-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU005692-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU001961-PA	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
OTAU014435-PA	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
OTAU002906-PA	4	Reactome: R-HSA-5689880;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-111465	"Ub-specific processing proteases";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins"
OTAU016621-PA	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
OTAU006407-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU012019-PA	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
OTAU007828-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
OTAU011765-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU012782-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
OTAU014357-PA	7	KEGG: 00620+2.3.3.9;KEGG: 00630+2.3.3.9;MetaCyc: PWY-6969;MetaCyc: PWY-7854;MetaCyc: PWY-7118;MetaCyc: PWY-7295;MetaCyc: PWY-7294	"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Chitin degradation to ethanol";"L-arabinose degradation IV";"D-xylose degradation IV"
OTAU011981-PA	17	Reactome: R-HSA-5656169;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-174411	"Termination of translesion DNA synthesis";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere"
OTAU001991-PA	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
OTAU003906-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU014895-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
OTAU005457-PA	8	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5743	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle"
OTAU002890-PA	10	MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174	"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Mevalonate pathway I";"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)"
OTAU009849-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU003579-PA	9	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
OTAU007644-PA	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
OTAU008485-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
OTAU015405-PA	12	Reactome: R-HSA-70263;MetaCyc: PWY-1861;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13	"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Methane metabolism"
OTAU003423-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
OTAU016269-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU011227-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU008650-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU008498-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU005187-PA	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
OTAU011438-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
OTAU008441-PA	27	Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
OTAU005553-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
OTAU004890-PA	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
OTAU004219-PA	25	Reactome: R-HSA-8936459;Reactome: R-HSA-8941858;Reactome: R-HSA-8949275;Reactome: R-HSA-8951936;Reactome: R-HSA-8939247;Reactome: R-HSA-8877330;Reactome: R-HSA-8941333;Reactome: R-HSA-9616222;Reactome: R-HSA-8939245;Reactome: R-HSA-8939902;Reactome: R-HSA-8935964;Reactome: R-HSA-8941326;Reactome: R-HSA-8940973;Reactome: R-HSA-8951911;Reactome: R-HSA-9018519;Reactome: R-HSA-8939236;Reactome: R-HSA-8934593;Reactome: R-HSA-8941332;Reactome: R-HSA-8941284;Reactome: R-HSA-8939246;Reactome: R-HSA-8939256;Reactome: R-HSA-8931987;Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-8878166	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX3 expression and activity";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates bone development";"RUNX2 regulates osteoblast differentiation";"RUNX3 regulates RUNX1-mediated transcription";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Transcriptional regulation by RUNX2"
OTAU016235-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU000747-PA	6	Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
OTAU007473-PA	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
OTAU010042-PA	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
OTAU001315-PA	1	Reactome: R-HSA-264876	"Insulin processing"
OTAU014553-PA	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
OTAU000016-PA	3	KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
OTAU003444-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU000438-PA	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
OTAU014065-PA	52	Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-76066;Reactome: R-HSA-73776;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
OTAU016196-PA	4	Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664	"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Neddylation"
OTAU002596-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
OTAU003031-PA	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation"
OTAU006154-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
OTAU009271-PA	5	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
OTAU008433-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU012107-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU006730-PA	6	KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Other glycan degradation"
OTAU010004-PA	3	Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978	"Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production"
OTAU015687-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
OTAU005818-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU009309-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU008178-PA	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
OTAU001083-PA	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
OTAU002716-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
OTAU010039-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
OTAU013199-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
OTAU005899-PA	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
OTAU008156-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
OTAU014104-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU010753-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU005077-PA	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
OTAU010768-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU010463-PA	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
OTAU010206-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
OTAU006940-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
OTAU007651-PA	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
OTAU010217-PA	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
OTAU016237-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
OTAU012958-PA	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
OTAU001966-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU012921-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU003229-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
OTAU001411-PA	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
OTAU014872-PA	1	Reactome: R-HSA-1296061	"HCN channels"
OTAU000268-PA	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
OTAU004999-PA	6	Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism"
OTAU004392-PA	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
OTAU006650-PA	1	Reactome: R-HSA-419771	"Opsins"
OTAU016127-PA	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
OTAU011776-PA	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"RAF activation";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins"
OTAU003365-PA	12	Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955	"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation"
OTAU012479-PA	7	MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III"
OTAU002533-PA	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
OTAU009683-PA	56	Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323	"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Degradation of AXIN";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling"
OTAU005364-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU008871-PA	3	Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
OTAU005056-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU006158-PA	5	MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
OTAU013665-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU003259-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU016266-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU002931-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
OTAU009897-PA	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
OTAU002813-PA	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
OTAU009867-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU001014-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU007715-PA	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
OTAU004223-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
OTAU008033-PA	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN"
OTAU003610-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU015485-PA	6	Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-416993	"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors"
OTAU004312-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
OTAU011620-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU006531-PA	8	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
OTAU008668-PA	16	Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
OTAU001759-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU006541-PA	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
OTAU002914-PA	4	Reactome: R-HSA-2408557;Reactome: R-HSA-379716;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
OTAU000278-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
OTAU012337-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
OTAU015021-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU001729-PA	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
OTAU002131-PA	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
OTAU003904-PA	8	Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
OTAU004091-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU001316-PA	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
OTAU014773-PA	13	MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5913	"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)"
OTAU001617-PA	7	Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
OTAU005993-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU013321-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
OTAU007952-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU003885-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
OTAU015289-PA	1	Reactome: R-HSA-9636383	"Prevention of phagosomal-lysosomal fusion"
OTAU000267-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
OTAU000423-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
OTAU008666-PA	13	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948	"Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants"
OTAU003717-PA	13	Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-177504	"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling"
OTAU009676-PA	7	Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-203927	"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis"
OTAU007631-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU002989-PA	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
OTAU009746-PA	3	Reactome: R-HSA-1660662;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Interleukin-1 signaling";"Neutrophil degranulation"
OTAU007615-PA	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
OTAU013338-PA	3	Reactome: R-HSA-3108214;Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
OTAU001356-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU004333-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU002801-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU005369-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
OTAU016432-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU013208-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU007351-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU006845-PA	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
OTAU005181-PA	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
OTAU005196-PA	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
OTAU011474-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU005042-PA	5	KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
OTAU001270-PA	19	Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825	"VLDL clearance";"Chylomicron remodeling";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"LDL remodeling";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Chylomicron clearance";"LDL clearance";"Scavenging by Class F Receptors";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis"
OTAU000788-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU006026-PA	4	KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27	"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism"
OTAU009152-PA	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
OTAU007713-PA	5	Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
OTAU002903-PA	9	Reactome: R-HSA-5649702;Reactome: R-HSA-9656255;Reactome: R-HSA-9656256;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110357	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Binding";"Defective OGG1 Substrate Processing";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1"
OTAU002669-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
OTAU000633-PA	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
OTAU014018-PA	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
OTAU011033-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU015976-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU004108-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
OTAU013644-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU007431-PA	27	Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-159236;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-159231;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-111367;Reactome: R-HSA-975957;Reactome: R-HSA-77595;Reactome: R-HSA-167200;Reactome: R-HSA-975956;Reactome: R-HSA-167242;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-8851708;Reactome: R-HSA-159227;Reactome: R-HSA-72086;Reactome: R-HSA-72187;Reactome: R-HSA-9010553	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"SLBP independent Processing of Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of Intronless Pre-mRNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"Signaling by FGFR2 IIIa TM";"Transport of the SLBP independent Mature mRNA";"mRNA Capping";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs"
OTAU002826-PA	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
OTAU007712-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU015063-PA	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
OTAU010834-PA	4	Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Mitotic Telophase/Cytokinesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
OTAU005252-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU001331-PA	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
OTAU005450-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
OTAU008783-PA	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
OTAU011673-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU005368-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
OTAU008757-PA	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
OTAU016159-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
OTAU012487-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU009248-PA	19	Reactome: R-HSA-525793;Reactome: R-HSA-4420097;Reactome: R-HSA-182971;Reactome: R-HSA-5663220;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-114604;Reactome: R-HSA-8964616;Reactome: R-HSA-194840;Reactome: R-HSA-8950505;Reactome: R-HSA-5625970;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-5627123;Reactome: R-HSA-428543	"Myogenesis";"VEGFA-VEGFR2 Pathway";"EGFR downregulation";"RHO GTPases Activate Formins";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"GPVI-mediated activation cascade";"G beta:gamma signalling through CDC42";"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate KTN1";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1"
OTAU016067-PA	13	Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117	"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"EPHA-mediated growth cone collapse";"Thermogenesis";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs"
OTAU008205-PA	42	KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7401;KEGG: 00623+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00592+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-6944;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6583;MetaCyc: PWY-6883;MetaCyc: PWY-5138;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-6863;MetaCyc: PWY-7654;MetaCyc: PWY-7779;MetaCyc: PWY-7778;MetaCyc: PWY-6435	"Fatty acid elongation";"Geraniol degradation";"Butanoate metabolism";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Fermentation to 2-methylbutanoate";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Toluene degradation";"beta-Alanine metabolism";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Fatty acid salvage";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"alpha-Linolenic acid metabolism";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Androstenedione degradation";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Caprolactam degradation";"Glutaryl-coa degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol I";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Valine, leucine and isoleucine degradation";"Aminobenzoate degradation";"Propanoate metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Phenylalanine metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to hexanol (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Methyl tert-butyl ether degradation";"2-methylpropene degradation";"4-hydroxybenzoate biosynthesis III (plants)"
OTAU012715-PA	5	Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
OTAU003396-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU014130-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
OTAU004681-PA	14	Reactome: R-HSA-3769402;Reactome: R-HSA-9648025;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9634638;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-69273	"Deactivation of the beta-catenin transactivating complex";"EML4 and NUDC in mitotic spindle formation";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Cyclin A/B1/B2 associated events during G2/M transition"
OTAU014735-PA	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
OTAU011844-PA	8	Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-111463	"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs"
OTAU002967-PA	33	Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168271	"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"HCMV Early Events";"HCMV Late Events";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus"
OTAU005582-PA	9	KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-7112	"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification"
OTAU008803-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
OTAU004140-PA	52	Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-5578749;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-203927;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-73780;Reactome: R-HSA-167287;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-73776;Reactome: R-HSA-1834949;Reactome: R-HSA-76071	"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Transcriptional regulation by small RNAs";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"MicroRNA (miRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Chain Elongation";"HIV elongation arrest and recovery";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Transcription Termination";"mRNA Capping";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
OTAU005903-PA	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
OTAU005293-PA	6	MetaCyc: PWY-6731;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1	"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation V";"Glycogen degradation II";"Starch and sucrose metabolism"
OTAU014543-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU000427-PA	6	Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;MetaCyc: PWY-6906;MetaCyc: PWY-5514	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II"
OTAU000451-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
OTAU006042-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU001313-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU008877-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
OTAU001434-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
OTAU014333-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU008143-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU002195-PA	9	Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-9608287;Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-9608290;Reactome: R-HSA-9630222	"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Defective MUTYH substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Defective MUTYH substrate processing";"Defective NTHL1 substrate binding"
OTAU005439-PA	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
OTAU015470-PA	4	Reactome: R-HSA-4755583;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199	"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
OTAU002144-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU006895-PA	4	KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193	"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
OTAU015311-PA	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock"
OTAU002780-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU003163-PA	9	Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801	"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD"
OTAU004939-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
OTAU001823-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU007714-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU007475-PA	57	Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-69481	"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Degradation of AXIN";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints"
OTAU003222-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU015316-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU008062-PA	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
OTAU014426-PA	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
OTAU007922-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
OTAU000436-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU012615-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU013680-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
OTAU010939-PA	6	Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU008950-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
OTAU014656-PA	16	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
OTAU002393-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU010371-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU000370-PA	5	Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-2426168	"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)"
OTAU002719-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
OTAU009073-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
OTAU009624-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU010368-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
OTAU015905-PA	14	Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243	"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery"
OTAU010760-PA	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
OTAU009909-PA	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
OTAU011808-PA	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
OTAU017126-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU009093-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
OTAU011588-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
OTAU001982-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
OTAU004928-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
OTAU008763-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU000933-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU014129-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
OTAU005546-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU010513-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
OTAU009643-PA	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
OTAU009848-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU013395-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU012290-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU008921-PA	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
OTAU016469-PA	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
OTAU000484-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU013016-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
OTAU004487-PA	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
OTAU014017-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
OTAU001034-PA	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
OTAU006134-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
OTAU001304-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
OTAU008237-PA	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
OTAU000683-PA	4	MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-8072	"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Alanine racemization"
OTAU005101-PA	10	KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-7909	"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)"
OTAU000119-PA	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
OTAU008994-PA	14	Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-193692	"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR"
OTAU010391-PA	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
OTAU001698-PA	8	Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
OTAU014541-PA	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
OTAU016217-PA	6	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
OTAU003932-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU008964-PA	13	Reactome: R-HSA-2029485;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;MetaCyc: PWY-7039;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11	"Role of phospholipids in phagocytosis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"DAP12 signaling";"Phosphatidate metabolism, as a signaling molecule";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism"
OTAU009842-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
OTAU006251-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
OTAU010828-PA	3	Reactome: R-HSA-6798695;Reactome: R-HSA-5223345;Reactome: R-HSA-446203	"Neutrophil degranulation";"Miscellaneous transport and binding events";"Asparagine N-linked glycosylation"
OTAU010143-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU011232-PA	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
OTAU008857-PA	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
OTAU001113-PA	10	KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11	"Arginine and proline metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis"
OTAU004376-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
OTAU003776-PA	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
OTAU004196-PA	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
OTAU015815-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
OTAU014053-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
OTAU004491-PA	14	Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-112382	"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex"
OTAU011130-PA	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
OTAU000413-PA	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
OTAU003849-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU005479-PA	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
OTAU005602-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
OTAU000938-PA	32	Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167152	"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
OTAU011950-PA	4	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
OTAU015068-PA	8	MetaCyc: PWY-8086;MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Pyruvate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis"
OTAU002040-PA	12	Reactome: R-HSA-71240;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-7901;MetaCyc: PWY-6309;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-6936;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801	"Tryptophan catabolism";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion"
OTAU006872-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU008890-PA	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-7112	"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification"
OTAU017069-PA	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
OTAU005440-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
OTAU010419-PA	6	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-201722	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex"
OTAU007811-PA	8	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
OTAU010284-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU009101-PA	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
OTAU007978-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU008140-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU013099-PA	4	Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes"
OTAU004338-PA	2	MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
OTAU010798-PA	6	MetaCyc: PWY-5789;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-6722	"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis"
OTAU011816-PA	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
OTAU010559-PA	27	Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159227	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA"
OTAU007381-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU000631-PA	2	Reactome: R-HSA-392154;Reactome: R-HSA-1222556	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes"
OTAU002741-PA	5	KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560;MetaCyc: PWY-6892	"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
OTAU001312-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU015298-PA	21	KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7227;MetaCyc: PWY-7222	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II"
OTAU004914-PA	14	MetaCyc: PWY-5104;KEGG: 00270+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5108;MetaCyc: PWY-5057;MetaCyc: PWY-5103;MetaCyc: PWY-5078;KEGG: 00290+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5101;KEGG: 00966+2.6.1.42;Reactome: R-HSA-70895	"L-isoleucine biosynthesis IV";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis V";"L-valine degradation II";"L-isoleucine biosynthesis III";"L-isoleucine degradation II";"Valine, leucine and isoleucine biosynthesis";"Pantothenate and CoA biosynthesis";"L-leucine degradation III";"L-isoleucine biosynthesis II";"Glucosinolate biosynthesis";"Branched-chain amino acid catabolism"
OTAU014030-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU007312-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU008235-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
OTAU009810-PA	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
OTAU008099-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU013915-PA	26	Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606	"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
OTAU009771-PA	1	Reactome: R-HSA-419771	"Opsins"
OTAU001180-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU006335-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
OTAU002279-PA	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
OTAU016792-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU001421-PA	16	Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-8853884	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX"
OTAU011917-PA	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
OTAU014674-PA	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
OTAU005514-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU000975-PA	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
OTAU014125-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU010317-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU009882-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU002032-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU011993-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU009424-PA	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
OTAU007194-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
OTAU014570-PA	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
OTAU005084-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU009507-PA	14	Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery"
OTAU000456-PA	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
OTAU003754-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU007111-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
OTAU000974-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
OTAU010759-PA	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
OTAU016604-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
OTAU001355-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
OTAU003697-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
OTAU006877-PA	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
OTAU005237-PA	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
OTAU016531-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU009302-PA	24	Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU008776-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU011795-PA	8	Reactome: R-HSA-4086398;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-4608870;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263;Reactome: R-HSA-373080	"Ca2+ pathway";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination";"Class B/2 (Secretin family receptors)"
OTAU007216-PA	13	MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916	"Chitin degradation III (Serratia)";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation"
OTAU000099-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU004027-PA	4	Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-156581	"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Methylation"
OTAU014487-PA	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
OTAU006645-PA	11	Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
OTAU010041-PA	1	Reactome: R-HSA-977443	"GABA receptor activation"
OTAU015713-PA	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"ATP biosynthesis";"Photosynthesis";"Ion channel transport";"Insulin receptor recycling"
OTAU005959-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
OTAU000020-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU010139-PA	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
OTAU011718-PA	4	Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2	"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
OTAU004675-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU012929-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU011481-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU010415-PA	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
OTAU013577-PA	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
OTAU003108-PA	11	Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680	"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity"
OTAU006433-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU004484-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
OTAU003381-PA	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
OTAU013156-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
OTAU010578-PA	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
OTAU003236-PA	16	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
OTAU014394-PA	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
OTAU001903-PA	4	KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III"
OTAU011815-PA	1	Reactome: R-HSA-6783984	"Glycine degradation"
OTAU013729-PA	6	MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-3322077;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18	"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism"
OTAU003123-PA	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
OTAU001346-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
OTAU005545-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU004713-PA	5	Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-212300	"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"DNA methylation";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA"
OTAU001183-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU000550-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
OTAU015686-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU006197-PA	6	MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)"
OTAU008906-PA	19	Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497	"Scavenging by Class F Receptors";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"LDL clearance";"Chylomicron clearance";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Chylomicron assembly";"Post-translational protein phosphorylation";"LDL remodeling";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Chylomicron remodeling";"Scavenging by Class H Receptors"
OTAU011054-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
OTAU007613-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU003233-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU006024-PA	14	MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587	"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)"
OTAU015840-PA	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
OTAU008052-PA	1	Reactome: R-HSA-8964038	"LDL clearance"
OTAU008875-PA	182	Reactome: R-HSA-5654727;Reactome: R-HSA-901032;Reactome: R-HSA-6807004;Reactome: R-HSA-5632684;Reactome: R-HSA-2559580;Reactome: R-HSA-912631;Reactome: R-HSA-2173796;Reactome: R-HSA-156902;Reactome: R-HSA-532668;Reactome: R-HSA-201681;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-174048;Reactome: R-HSA-8941858;Reactome: R-HSA-9013507;Reactome: R-HSA-5689896;Reactome: R-HSA-2122947;Reactome: R-HSA-8852276;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-5689901;Reactome: R-HSA-9637628;Reactome: R-HSA-205043;Reactome: R-HSA-75815;Reactome: R-HSA-1253288;Reactome: R-HSA-2122948;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-174178;Reactome: R-HSA-5675482;Reactome: R-HSA-68827;Reactome: R-HSA-977225;Reactome: R-HSA-8876493;Reactome: R-HSA-382556;Reactome: R-HSA-6804756;Reactome: R-HSA-917729;Reactome: R-HSA-5696395;Reactome: R-HSA-3322077;Reactome: R-HSA-9010553;Reactome: R-HSA-182971;Reactome: R-HSA-211733;Reactome: R-HSA-8856828;Reactome: R-HSA-72695;Reactome: R-HSA-5656169;Reactome: R-HSA-937042;Reactome: R-HSA-6804760;Reactome: R-HSA-975956;Reactome: R-HSA-5696394;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5696400;Reactome: R-HSA-2173791;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5205685;Reactome: R-HSA-69481;Reactome: R-HSA-937041;Reactome: R-HSA-9033241;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1799339;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-72649;Reactome: R-HSA-175474;Reactome: R-HSA-1358803;Reactome: R-HSA-8948747;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6804757;Reactome: R-HSA-9633012;Reactome: R-HSA-68949;Reactome: R-HSA-2559585;Reactome: R-HSA-2979096;Reactome: R-HSA-5693607;Reactome: R-HSA-5654726;Reactome: R-HSA-975144;Reactome: R-HSA-450302;Reactome: R-HSA-69231;Reactome: R-HSA-69541;Reactome: R-HSA-2894862;Reactome: R-HSA-5654732;Reactome: R-HSA-3785653;Reactome: R-HSA-6791226;Reactome: R-HSA-174084;Reactome: R-HSA-445989;Reactome: R-HSA-5655862;Reactome: R-HSA-2672351;Reactome: R-HSA-5668541;Reactome: R-HSA-4641263;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-6783310;Reactome: R-HSA-168638;Reactome: R-HSA-2644606;Reactome: R-HSA-5358346;Reactome: R-HSA-8863795;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-180534;Reactome: R-HSA-9636383;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9014325;Reactome: R-HSA-975163;Reactome: R-HSA-168928;Reactome: R-HSA-1169408;Reactome: R-HSA-110320;Reactome: R-HSA-975110;Reactome: R-HSA-1236382;Reactome: R-HSA-3134975;Reactome: R-HSA-209543;Reactome: R-HSA-937072;Reactome: R-HSA-937039;Reactome: R-HSA-187577;Reactome: R-HSA-5357905;Reactome: R-HSA-156827;Reactome: R-HSA-2173795;Reactome: R-HSA-8866654;Reactome: R-HSA-5696397;Reactome: R-HSA-9645460;Reactome: R-HSA-6781827;Reactome: R-HSA-209560;Reactome: R-HSA-192823;Reactome: R-HSA-9013973;Reactome: R-HSA-5675221;Reactome: R-HSA-5685942;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-5357956;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-2691232;Reactome: R-HSA-9613829;Reactome: R-HSA-4641258;Reactome: R-HSA-936440;Reactome: R-HSA-69601;Reactome: R-HSA-110312;Reactome: R-HSA-8951664;Reactome: R-HSA-5656121;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-2565942;Reactome: R-HSA-168927;Reactome: R-HSA-5362768;Reactome: R-HSA-174490;Reactome: R-HSA-1236974;Reactome: R-HSA-8866652;Reactome: R-HSA-400253;Reactome: R-HSA-975957;Reactome: R-HSA-8849469;Reactome: R-HSA-110314;Reactome: R-HSA-2173788;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5693565;Reactome: R-HSA-936964;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-3769402;Reactome: R-HSA-1295596;Reactome: R-HSA-9646399;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-6782210;Reactome: R-HSA-2408557;Reactome: R-HSA-5654733;Reactome: R-HSA-2559582;Reactome: R-HSA-450321;Reactome: R-HSA-180585	"Negative regulation of FGFR2 signaling";"ER Quality Control Compartment (ERQC)";"Negative regulation of MET activity";"Hedgehog 'on' state";"Oxidative Stress Induced Senescence";"Regulation of signaling by CBL";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Peptide chain elongation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"TCF dependent signaling in response to WNT";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of RUNX3 expression and activity";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Ovarian tumor domain proteases";"NOTCH1 Intracellular Domain Regulates Transcription";"The role of GTSE1 in G2/M progression after G2 checkpoint";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Metalloprotease DUBs";"Modulation by Mtb of host immune system";"NRIF signals cell death from the nucleus";"Ubiquitin-dependent degradation of Cyclin D";"Downregulation of ERBB4 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of necroptotic cell death";"CDT1 association with the CDC6:ORC:origin complex";"Amyloid fiber formation";"InlA-mediated entry of Listeria monocytogenes into host cells";"ABC-family proteins mediated transport";"Regulation of TP53 Activity through Phosphorylation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Formation of Incision Complex in GG-NER";"Glycogen synthesis";"Regulation of expression of SLITs and ROBOs";"EGFR downregulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Clathrin-mediated endocytosis";"Formation of the ternary complex, and subsequently, the 43S complex";"Termination of translesion DNA synthesis";"IRAK2 mediated activation of TAK1 complex";"Regulation of TP53 Activity through Methylation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"DNA Damage Recognition in GG-NER";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Dual Incision in GG-NER";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Pink/Parkin Mediated Mitophagy";"G2/M Checkpoints";"IKK complex recruitment mediated by RIP1";"Peroxisomal protein import";"UCH proteinases";"Downstream TCR signaling";"SRP-dependent cotranslational protein targeting to membrane";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Translation initiation complex formation";"Assembly Of The HIV Virion";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of PTEN localization";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of TP53 Degradation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Orc1 removal from chromatin";"Oncogene Induced Senescence";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Processing of DNA double-strand break ends";"Negative regulation of FGFR1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"Cyclin D associated events in G1";"Stabilization of p53";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulation of FGFR3 signaling";"Myoclonic epilepsy of Lafora";"Major pathway of rRNA processing in the nucleolus and cytosol";"Autodegradation of Cdh1 by Cdh1:APC/C";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Translesion synthesis by POLK";"Stimuli-sensing channels";"TNFR2 non-canonical NF-kB pathway";"Regulation of FZD by ubiquitination";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Fanconi Anemia Pathway";"NOD1/2 Signaling Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Hedgehog ligand biogenesis";"Downregulation of ERBB2 signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Vpu mediated degradation of CD4";"Prevention of phagosomal-lysosomal fusion";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"ISG15 antiviral mechanism";"Translesion Synthesis by POLH";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of innate immune responses to cytosolic DNA";"p75NTR recruits signalling complexes";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK1 recruits IKK complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of TNFR1 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"E3 ubiquitin ligases ubiquitinate target proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Alpha-protein kinase 1 signaling pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NF-kB is activated and signals survival";"Viral mRNA Translation";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulation of MAPK pathway";"HDR through Homologous Recombination (HRR)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"TNFR1-induced NFkappaB signaling pathway";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Chaperone Mediated Autophagy";"Degradation of DVL";"Negative regulators of DDX58/IFIH1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Translesion synthesis by REV1";"Neddylation";"Translesion synthesis by POLI";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"TICAM1, RIP1-mediated IKK complex recruitment";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Membrane binding and targetting of GAG proteins";"ER-Phagosome pathway";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Circadian Clock";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of TGF-beta receptor signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Deactivation of the beta-catenin transactivating complex";"Spry regulation of FGF signaling";"Aggrephagy";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Selenocysteine synthesis";"Negative regulation of FGFR4 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Vif-mediated degradation of APOBEC3G"
OTAU010370-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
OTAU007938-PA	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
OTAU016339-PA	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
OTAU006146-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
OTAU001497-PA	6	Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
OTAU009128-PA	5	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
OTAU004984-PA	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
OTAU007374-PA	4	KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
OTAU005833-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU012423-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU005787-PA	57	Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5689603	"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Neutrophil degranulation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Degradation of AXIN";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases"
OTAU005543-PA	3	Reactome: R-HSA-1660499;Reactome: R-HSA-111465;KEGG: 04660+2.7.10.2	"Synthesis of PIPs at the plasma membrane";"Apoptotic cleavage of cellular proteins";"T cell receptor signaling pathway"
OTAU007780-PA	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
OTAU008618-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
OTAU000706-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU017165-PA	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
OTAU017009-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU003755-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU003147-PA	3	Reactome: R-HSA-71403;KEGG: 00430+1.4.1.1;KEGG: 00250+1.4.1.1	"Citric acid cycle (TCA cycle)";"Taurine and hypotaurine metabolism";"Alanine, aspartate and glutamate metabolism"
OTAU000352-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
OTAU005043-PA	8	Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress"
OTAU010237-PA	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
OTAU008693-PA	5	KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-6922;MetaCyc: PWY-3341	"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)"
OTAU001056-PA	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
OTAU008145-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
OTAU000304-PA	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
OTAU012895-PA	6	KEGG: 00230+4.1.1.21;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;MetaCyc: PWY-6123	"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I"
OTAU011020-PA	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
OTAU007878-PA	2	Reactome: R-HSA-5619055;Reactome: R-HSA-425561	"Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI)";"Sodium/Calcium exchangers"
OTAU007641-PA	56	Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276	"UCH proteinases";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint"
OTAU009782-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
OTAU011730-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
OTAU014090-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU016268-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU011401-PA	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU007826-PA	1	Reactome: R-HSA-6804115	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
OTAU013314-PA	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU000139-PA	18	MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1	"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism"
OTAU014755-PA	6	Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs"
OTAU003122-PA	7	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
OTAU008697-PA	8	KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171	"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis"
OTAU006751-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU012991-PA	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
OTAU014854-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
OTAU000107-PA	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
OTAU007893-PA	12	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
OTAU011780-PA	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
OTAU003099-PA	1	Reactome: R-HSA-3295583	"TRP channels"
OTAU001460-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU003219-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU016490-PA	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
OTAU003499-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU009194-PA	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU011444-PA	1	Reactome: R-HSA-71262	"Carnitine synthesis"
OTAU010376-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU005455-PA	8	Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Activation of RAC1";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
OTAU002845-PA	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
OTAU008056-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
OTAU001062-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
OTAU002407-PA	8	KEGG: 00051+4.2.1.47;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-66;MetaCyc: PWY-7573;MetaCyc: PWY-5740;Reactome: R-HSA-6787639;MetaCyc: PWY-5739	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis"
OTAU009678-PA	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
OTAU008760-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU000902-PA	5	Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
OTAU013748-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
OTAU004841-PA	6	Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
OTAU007487-PA	20	Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801	"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair"
OTAU006535-PA	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
OTAU004543-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
OTAU013657-PA	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
OTAU005908-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU008888-PA	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
OTAU010320-PA	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
OTAU003048-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
OTAU002578-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
OTAU010878-PA	3	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
OTAU001285-PA	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
OTAU002895-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
OTAU002672-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU015562-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU009805-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU002631-PA	16	Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
OTAU005121-PA	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
OTAU002910-PA	14	Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-4086398	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway"
OTAU011754-PA	8	Reactome: R-HSA-77387;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2	"Insulin receptor recycling";"Ion channel transport";"Photosynthesis";"ATP biosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Oxidative phosphorylation"
OTAU017302-PA	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
OTAU003379-PA	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
OTAU008206-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU017440-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU015601-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU016002-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
OTAU001839-PA	11	Reactome: R-HSA-8862803;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8943724;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-450341;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-2871796	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of PTEN gene transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the AP-1 family of transcription factors";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"FCERI mediated MAPK activation"
OTAU003065-PA	3	Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
OTAU002083-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU004511-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU014112-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU009544-PA	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
OTAU009400-PA	27	Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159227	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA"
OTAU010325-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU015680-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
OTAU011010-PA	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
OTAU002583-PA	9	Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type"
OTAU001544-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU014654-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU005222-PA	15	Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-2173796	"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
OTAU009439-PA	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
OTAU010167-PA	3	Reactome: R-HSA-5694530;Reactome: R-HSA-948021;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport"
OTAU008403-PA	7	Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
OTAU005151-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU013815-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU015563-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
OTAU007495-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
OTAU005399-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
OTAU008569-PA	3	Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174	"Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex"
OTAU017232-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU003196-PA	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
OTAU003363-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU006371-PA	8	Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-912446	"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination"
OTAU013782-PA	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
OTAU006608-PA	12	KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7238;Reactome: R-HSA-173599	"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Glycogen synthesis";"Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate"
OTAU012329-PA	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
OTAU001351-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU013541-PA	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
OTAU015597-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
OTAU012324-PA	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
OTAU009936-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU013201-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
OTAU001702-PA	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
OTAU007235-PA	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
OTAU001679-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU013246-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
OTAU003547-PA	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
OTAU012460-PA	9	KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52	"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series"
OTAU009369-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU007660-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
OTAU013949-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
OTAU001223-PA	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
OTAU007219-PA	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
OTAU009852-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU000858-PA	57	Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184	"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Degradation of AXIN";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
OTAU009526-PA	6	Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-5620922	"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
OTAU000146-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU003850-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU001055-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
OTAU000859-PA	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
OTAU011896-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU007809-PA	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
OTAU002841-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
OTAU008241-PA	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
OTAU014485-PA	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
OTAU011150-PA	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
OTAU000836-PA	15	Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333	"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated"
OTAU012322-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU010927-PA	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
OTAU001777-PA	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
OTAU004447-PA	5	MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692	"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation"
OTAU012165-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
OTAU000369-PA	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
OTAU015368-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU003763-PA	13	MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-7659	"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis"
OTAU006216-PA	13	KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5108;MetaCyc: PWY-7857;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118	"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Methane metabolism";"Ethanol oxidation";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Chitin degradation to ethanol"
OTAU010560-PA	27	Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379	"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"HCMV Late Events"
OTAU000803-PA	8	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin"
OTAU003215-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
OTAU008442-PA	27	Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-180746	"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"HCMV Early Events";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Nuclear import of Rev protein"
OTAU002048-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU013802-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
OTAU009592-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
OTAU002268-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
OTAU006640-PA	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
OTAU010778-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU009182-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
OTAU011415-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
OTAU016742-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
OTAU009646-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU016501-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
OTAU003700-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
OTAU008221-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
OTAU000941-PA	5	Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
OTAU009069-PA	4	Reactome: R-HSA-4086398;Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-3238698	"Ca2+ pathway";"Class B/2 (Secretin family receptors)";"PCP/CE pathway";"WNT ligand biogenesis and trafficking"
OTAU005781-PA	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
OTAU007643-PA	2	Reactome: R-HSA-606279;Reactome: R-HSA-6783310	"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway"
OTAU007185-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
OTAU009473-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
OTAU007121-PA	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
OTAU003835-PA	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
OTAU005136-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
OTAU001550-PA	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
OTAU011365-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU008046-PA	24	Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861	"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly"
OTAU008993-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU015185-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
OTAU002951-PA	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
OTAU000006-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
OTAU015033-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU000644-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU003008-PA	11	MetaCyc: PWY-6538;MetaCyc: PWY-6596;MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6608;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;MetaCyc: PWY-6607	"Caffeine degradation III (bacteria, via demethylation)";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Guanosine nucleotides degradation I"
OTAU003184-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU006623-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
OTAU003409-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
OTAU000570-PA	16	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
OTAU017044-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
OTAU002115-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU002991-PA	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism"
OTAU003537-PA	52	Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603	"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"UCH proteinases"
OTAU011265-PA	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
OTAU004879-PA	3	Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
OTAU007191-PA	4	KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258	"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
OTAU012430-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU001070-PA	11	Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-5689880;Reactome: R-HSA-73779	"Transcription of the HIV genome";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
OTAU008657-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU006256-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU004525-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
OTAU006957-PA	56	Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113	"ABC-family proteins mediated transport";"Degradation of AXIN";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1"
OTAU016007-PA	7	MetaCyc: PWY-7818;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886	"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Synthesis of PE";"Synthesis of PC";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
OTAU002879-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU000536-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
OTAU006297-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
OTAU013445-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU010908-PA	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
OTAU011347-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
OTAU009407-PA	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
OTAU005398-PA	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
OTAU015045-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
OTAU001178-PA	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
OTAU004062-PA	6	Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-191859	"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly"
OTAU001366-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
OTAU012100-PA	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
OTAU004143-PA	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU005850-PA	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
OTAU007059-PA	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
OTAU006334-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
OTAU014356-PA	5	MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
OTAU011742-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
OTAU000823-PA	4	KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
OTAU013820-PA	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
OTAU000978-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU010796-PA	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
OTAU015649-PA	3	KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45	"Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
OTAU004339-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU006639-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU011732-PA	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
OTAU017011-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU008465-PA	4	Reactome: R-HSA-499943;Reactome: R-HSA-6798695;KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123	"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
OTAU002668-PA	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
OTAU014924-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU011701-PA	11	Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-72163;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"mRNA Splicing - Major Pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
OTAU008587-PA	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
OTAU000891-PA	57	Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764	"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling"
OTAU004504-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU007107-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU007080-PA	10	Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
OTAU002579-PA	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
OTAU004648-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU017057-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
OTAU000693-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
OTAU016455-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
OTAU006148-PA	5	MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism"
OTAU003845-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU005168-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU010525-PA	4	KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
OTAU001135-PA	11	KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-882	"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)"
OTAU004040-PA	11	Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-1268020;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111463	"Regulation of the apoptosome activity";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Mitochondrial protein import";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs"
OTAU014010-PA	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
OTAU014111-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU004827-PA	25	Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483	"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Gap junction assembly";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Kinesins";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs"
OTAU000625-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
OTAU010008-PA	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
OTAU004043-PA	5	MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"Protein ubiquitination";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
OTAU008003-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU011299-PA	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
OTAU002107-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU011791-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU012903-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU009730-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU011753-PA	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"ATP biosynthesis";"Photosynthesis";"Ion channel transport";"Insulin receptor recycling"
OTAU005733-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU011125-PA	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
OTAU011349-PA	14	MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-7112;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-499943;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;Reactome: R-HSA-156590;MetaCyc: PWY-6370;KEGG: 00053+1.8.5.1	"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Ascorbate and aldarate metabolism"
OTAU001608-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU014429-PA	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
OTAU015648-PA	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
OTAU010441-PA	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
OTAU000149-PA	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
OTAU012525-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU006277-PA	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
OTAU013580-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
OTAU009637-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU016107-PA	4	Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
OTAU012561-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
OTAU001244-PA	33	Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3301854	"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"HCMV Late Events";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly"
OTAU002874-PA	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
OTAU009513-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
OTAU003223-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
OTAU006732-PA	6	KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23	"Galactose metabolism";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation"
OTAU002283-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU002113-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU009662-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU003900-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU017096-PA	4	Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Complex I biogenesis";"Respiratory electron transport"
OTAU001898-PA	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
OTAU010507-PA	20	MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-735;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-5136	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)"
OTAU000750-PA	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU014441-PA	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
OTAU004285-PA	27	Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054	"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA"
OTAU016369-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU008338-PA	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
OTAU008647-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU009444-PA	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
OTAU004026-PA	10	Reactome: R-HSA-3000171;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;MetaCyc: PWY-7849;Reactome: R-HSA-977225;Reactome: R-HSA-2453902;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17	"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"Neutrophil degranulation";"Urate conversion to allantoin III";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I";"Purine metabolism"
OTAU000930-PA	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
OTAU003905-PA	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
OTAU003959-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
OTAU003924-PA	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
OTAU015762-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
OTAU006659-PA	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU001669-PA	42	KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-5109;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-1361;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6583;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-5138;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7654;MetaCyc: PWY-7778;MetaCyc: PWY-7779;MetaCyc: PWY-6435	"Geraniol degradation";"Butanoate metabolism";"Fatty acid elongation";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"Toluene degradation";"beta-Alanine metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid salvage";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Caprolactam degradation";"Glutaryl-coa degradation";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol I";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Propanoate metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Phenylalanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"2-methylpropene degradation";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)"
OTAU011852-PA	6	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport"
OTAU013909-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU006257-PA	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
OTAU017253-PA	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
OTAU009120-PA	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
OTAU001690-PA	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
OTAU010316-PA	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
OTAU003257-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU000154-PA	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
OTAU009335-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU003772-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
OTAU011702-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU008429-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU000429-PA	14	MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
OTAU010647-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
OTAU004172-PA	3	KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3	"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism"
OTAU002950-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
OTAU010165-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU006898-PA	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
OTAU007974-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
OTAU004584-PA	5	MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855	"Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
OTAU014093-PA	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
OTAU000382-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
OTAU011222-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU002883-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
OTAU003241-PA	21	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7222;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176	"Drug metabolism - other enzymes";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"UTP and CTP de novo biosynthesis"
OTAU006224-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
OTAU006853-PA	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
OTAU011037-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU006156-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
OTAU000538-PA	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
OTAU000030-PA	16	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
OTAU003736-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
OTAU010741-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
OTAU014143-PA	52	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5601884;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-203927;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73776;Reactome: R-HSA-76066;Reactome: R-HSA-167160;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-73863;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-75953;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-6803529	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"MicroRNA (miRNA) biogenesis";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Termination";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing"
OTAU012698-PA	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
OTAU008042-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
OTAU013347-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
OTAU015136-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU003110-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU010434-PA	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
OTAU010628-PA	24	Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-163359;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-420092	"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Glucagon signaling in metabolic regulation";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"Glucagon-type ligand receptors"
OTAU013733-PA	9	Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68952	"Polymerase switching";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation"
OTAU011719-PA	4	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69205	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"G1/S-Specific Transcription"
OTAU000457-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU003570-PA	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
OTAU001557-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU001182-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU016558-PA	4	KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
OTAU001013-PA	8	MetaCyc: PWY-4983;KEGG: 00250+6.3.4.5;Reactome: R-HSA-70635;MetaCyc: PWY-5154;MetaCyc: PWY-5;KEGG: 00220+6.3.4.5;MetaCyc: PWY-7400;MetaCyc: PWY-4984	"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Canavanine biosynthesis";"Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle"
OTAU000735-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
OTAU009311-PA	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
OTAU002242-PA	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
OTAU009768-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU012747-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
OTAU015403-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU010627-PA	24	Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-400042;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-392451	"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"G alpha (i) signalling events";"G-protein activation";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma"
OTAU013265-PA	5	Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955	"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
OTAU000688-PA	8	MetaCyc: PWY-4984;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-5154;MetaCyc: PWY-5;Reactome: R-HSA-70635;MetaCyc: PWY-4983;KEGG: 00220+4.3.2.1	"Urea cycle";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Canavanine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis"
OTAU007505-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
OTAU011421-PA	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
OTAU010276-PA	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
OTAU012319-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
OTAU008444-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU014108-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU002912-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
OTAU012888-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU002843-PA	5	MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
OTAU013683-PA	17	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Thermogenesis";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway"
OTAU001079-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
OTAU010104-PA	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
OTAU003764-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
OTAU002935-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU017178-PA	56	Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585	"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G"
OTAU000725-PA	16	Reactome: R-HSA-182218;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-196025;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-164939;Reactome: R-HSA-8856825	"Nef Mediated CD8 Down-regulation";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Formation of annular gap junctions";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"Nef mediated downregulation of CD28 cell surface expression";"Cargo recognition for clathrin-mediated endocytosis"
OTAU010321-PA	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
OTAU002045-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
OTAU003819-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
OTAU008106-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
OTAU014376-PA	4	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions";"ECM proteoglycans"
OTAU002570-PA	12	MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5870	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
OTAU009257-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU012743-PA	2	KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
OTAU004904-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU008739-PA	5	Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
OTAU001222-PA	12	KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7118;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1	"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Methane metabolism";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism"
OTAU013760-PA	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
OTAU011058-PA	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
OTAU003544-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU014581-PA	5	KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism"
OTAU011720-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU002851-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU002733-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
OTAU006319-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU007095-PA	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU012928-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU017332-PA	57	Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-382556	"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Degradation of AXIN";"ABC-family proteins mediated transport"
OTAU007341-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU007605-PA	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
OTAU015341-PA	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
OTAU000810-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
OTAU015362-PA	4	MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis"
OTAU003696-PA	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
OTAU000917-PA	6	MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3	"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism"
OTAU016270-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU006736-PA	6	Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52	"Serine biosynthesis";"Cysteine and methionine metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism"
OTAU013826-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU015286-PA	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
OTAU003599-PA	6	Reactome: R-HSA-191273;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-922	"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I"
OTAU004472-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
OTAU012224-PA	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
OTAU009195-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU015931-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU008369-PA	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
OTAU015002-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU017469-PA	29	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-674695	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
OTAU008453-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
OTAU002846-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
OTAU008476-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
OTAU005849-PA	4	Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism"
OTAU012944-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU002711-PA	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
OTAU010530-PA	16	Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-983168	"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU000967-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU000966-PA	4	MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782861;MetaCyc: PWY-6829	"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)"
OTAU004927-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
OTAU005556-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU015634-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU001280-PA	13	Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665	"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"LDL clearance";"EPH-ephrin mediated repulsion of cells"
OTAU006854-PA	5	Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;Reactome: R-HSA-6798695	"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation"
OTAU015240-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
OTAU010879-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
OTAU005442-PA	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
OTAU013474-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU008832-PA	3	Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193	"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
OTAU009508-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU003870-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
OTAU003252-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU001631-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU008543-PA	10	MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-7003	"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol"
OTAU007041-PA	18	KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416	"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)"
OTAU002383-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU009449-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU010635-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
OTAU017385-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU006507-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
OTAU004858-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU015640-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU001981-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
OTAU010886-PA	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
OTAU013348-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
OTAU012660-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
OTAU003294-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
OTAU010920-PA	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
OTAU010928-PA	8	Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
OTAU008903-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
OTAU001942-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU000828-PA	5	MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-4793954;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
OTAU002202-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU000588-PA	4	Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis"
OTAU015054-PA	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
OTAU009167-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU006828-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
OTAU001842-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU017290-PA	6	Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)"
OTAU003927-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
OTAU012956-PA	4	Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events"
OTAU008651-PA	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
OTAU002947-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
OTAU016325-PA	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
OTAU009343-PA	12	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition"
OTAU016833-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU014550-PA	20	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"mTOR signalling";"Amino acids regulate mTORC1";"Human papillomavirus infection";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Thermogenesis";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Macroautophagy";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection"
OTAU000216-PA	7	KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;MetaCyc: PWY-8043	"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis"
OTAU000348-PA	7	Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-2559586	"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence"
OTAU011949-PA	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
OTAU006846-PA	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
OTAU009875-PA	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
OTAU009749-PA	3	Reactome: R-HSA-5576893;Reactome: R-HSA-5576890;Reactome: R-HSA-1296072	"Phase 2 - plateau phase";"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels"
OTAU008989-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
OTAU009744-PA	17	MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-6609;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-7179;MetaCyc: PWY-5532;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-4202	"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage III";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Purine salvage";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)"
OTAU007084-PA	11	Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418597	"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events"
OTAU007802-PA	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
OTAU015593-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU006285-PA	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
OTAU004218-PA	25	Reactome: R-HSA-8941284;Reactome: R-HSA-8941332;Reactome: R-HSA-8939256;Reactome: R-HSA-8939246;Reactome: R-HSA-8931987;Reactome: R-HSA-8878166;Reactome: R-HSA-8939242;Reactome: R-HSA-8939243;Reactome: R-HSA-8939247;Reactome: R-HSA-8951936;Reactome: R-HSA-8941858;Reactome: R-HSA-8949275;Reactome: R-HSA-8936459;Reactome: R-HSA-8877330;Reactome: R-HSA-8939902;Reactome: R-HSA-8935964;Reactome: R-HSA-8939245;Reactome: R-HSA-9616222;Reactome: R-HSA-8941333;Reactome: R-HSA-8939236;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8951911;Reactome: R-HSA-8940973;Reactome: R-HSA-8941326	"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 regulates p14-ARF";"Regulation of RUNX3 expression and activity";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX2 expression and activity";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in BCR signaling";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates bone development"
OTAU006123-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU014462-PA	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
OTAU000058-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
OTAU007961-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
OTAU015711-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
OTAU000852-PA	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
OTAU004094-PA	17	MetaCyc: PWY-5913;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7115;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561	"Partial TCA cycle (obligate autotrophs)";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation"
OTAU004587-PA	7	Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
OTAU002546-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU013085-PA	4	KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817	"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
OTAU010283-PA	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
OTAU008845-PA	4	Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-166058	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
OTAU009883-PA	10	Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751	"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity"
OTAU009258-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU009151-PA	6	Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex"
OTAU015586-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU009636-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU012419-PA	3	Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation"
OTAU004128-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU005506-PA	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
OTAU003794-PA	1	KEGG: 00970+6.1.1.5	"Aminoacyl-tRNA biosynthesis"
OTAU001022-PA	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
OTAU003032-PA	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
OTAU014714-PA	10	Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837	"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation"
OTAU006351-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
OTAU016047-PA	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
OTAU000255-PA	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-202733;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Cell surface interactions at the vascular wall";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU007822-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU010827-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU017274-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
OTAU011356-PA	1	Reactome: R-HSA-5617833	"Cilium Assembly"
OTAU010243-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU002504-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU001583-PA	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
OTAU012889-PA	12	KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1861;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13	"Fructose and mannose metabolism";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Methane metabolism";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms"
OTAU005053-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU015047-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU014310-PA	10	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05163+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"HATs acetylate histones";"Human cytomegalovirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"PI3K-Akt signaling pathway";"Thermogenesis"
OTAU009273-PA	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
OTAU014231-PA	24	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs"
OTAU011867-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
OTAU003436-PA	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
OTAU006729-PA	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214	"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
OTAU009254-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
OTAU000838-PA	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
OTAU001779-PA	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
OTAU007120-PA	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
OTAU015439-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU004583-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU005822-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU011348-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU002568-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU010040-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU006899-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
OTAU006260-PA	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
OTAU003182-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU002104-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU001144-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU006230-PA	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
OTAU007134-PA	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
OTAU015900-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU012542-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis"
OTAU010196-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU002262-PA	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
OTAU007572-PA	17	MetaCyc: PWY-7197;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7224	"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"CMP phosphorylation";"Purine deoxyribonucleosides salvage"
OTAU013037-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU006018-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA"
OTAU004881-PA	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
OTAU005460-PA	4	KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
OTAU002164-PA	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
OTAU001913-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
OTAU009457-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU006921-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
OTAU009140-PA	11	Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1	"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"PKA activation";"Purine metabolism"
OTAU011731-PA	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU016108-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU013684-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
OTAU004549-PA	1	Reactome: R-HSA-74217	"Purine salvage"
OTAU004794-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU006037-PA	4	KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7849;MetaCyc: PWY-7394	"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Urate conversion to allantoin II"
OTAU016523-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU007453-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
OTAU015134-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU010929-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU010023-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU002750-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU013593-PA	12	Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-112382	"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex"
OTAU000582-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU002422-PA	6	KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23	"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation"
OTAU010876-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
OTAU009622-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
OTAU012471-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU010898-PA	6	MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484	"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)"
OTAU012994-PA	8	MetaCyc: PWY-6133;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5394;KEGG: 00790+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581	"(S)-reticuline biosynthesis II";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Betalamic acid biosynthesis";"Folate biosynthesis";"Catecholamine biosynthesis";"Tyrosine metabolism";"(S)-reticuline biosynthesis I"
OTAU006843-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
OTAU008041-PA	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
OTAU000675-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU012746-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
OTAU003569-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
OTAU000581-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
OTAU005054-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
OTAU000048-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU012088-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU008774-PA	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
OTAU003360-PA	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
OTAU013301-PA	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
OTAU009520-PA	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
OTAU003516-PA	24	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Kinesins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
OTAU009063-PA	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
OTAU014653-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU015605-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU009747-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
OTAU010218-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
OTAU004408-PA	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
OTAU000621-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU001064-PA	6	KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Photosynthesis";"Mitochondrial protein import";"Oxidative phosphorylation";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling"
OTAU011805-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU014757-PA	7	KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Fructose and mannose metabolism"
OTAU000200-PA	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
OTAU013232-PA	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
OTAU012462-PA	9	MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52	"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis"
OTAU002917-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU012323-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU001647-PA	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
OTAU002681-PA	9	KEGG: 00400+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00950+2.6.1.5;KEGG: 00960+2.6.1.5	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Tyrosine catabolism";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis"
OTAU006876-PA	13	MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2	"Methylaspartate cycle";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes"
OTAU008616-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
OTAU010428-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU006211-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU002664-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU005644-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
OTAU007760-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
OTAU001875-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU008174-PA	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
OTAU011451-PA	7	Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724	"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"HCMV Early Events";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription"
OTAU007344-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU007647-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
OTAU009551-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU010019-PA	13	KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822	"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Other glycan degradation";"Chitin degradation III (Serratia)"
OTAU012220-PA	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
OTAU014415-PA	9	KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Other glycan degradation"
OTAU012473-PA	5	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation"
OTAU012523-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU001278-PA	6	MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis"
OTAU005464-PA	15	Reactome: R-HSA-8863795;Reactome: R-HSA-9665250;Reactome: R-HSA-1236382;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-9665244;Reactome: R-HSA-9665249;Reactome: R-HSA-9665245;Reactome: R-HSA-9652282;Reactome: R-HSA-9665233;Reactome: R-HSA-9634285;Reactome: R-HSA-1227986;Reactome: R-HSA-9665251;Reactome: R-HSA-9665246;Reactome: R-HSA-9665247	"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to osimertinib"
OTAU008439-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
OTAU006802-PA	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
OTAU007877-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
OTAU008456-PA	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
OTAU005636-PA	3	KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17	"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Purine metabolism"
OTAU002184-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
OTAU011660-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU012943-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU001060-PA	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase"
OTAU017429-PA	17	MetaCyc: PWY-7179;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;MetaCyc: PWY-4202;MetaCyc: PWY-6611;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-6609;MetaCyc: PWY-6608;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1	"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage V";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Guanine and guanosine salvage";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine metabolism"
OTAU008213-PA	26	Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Kinesins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
OTAU016863-PA	5	Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558	"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
OTAU001670-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
OTAU009632-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
OTAU000257-PA	13	MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.66;KEGG: 00760+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Purine catabolism";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism"
OTAU006482-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU003758-PA	13	MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1	"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis"
OTAU000795-PA	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
OTAU008039-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU007090-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU012243-PA	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020	"Oxidative phosphorylation";"Cristae formation";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Mitochondrial protein import"
OTAU013756-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
OTAU010543-PA	5	MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41	"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
OTAU000637-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
OTAU006734-PA	18	MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482925	"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG"
OTAU005387-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
OTAU011287-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
OTAU003448-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
OTAU005598-PA	7	KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;MetaCyc: PWY-6605;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7807	"Purine metabolism";"(aminomethyl)phosphonate degradation";"Adenine and adenosine salvage II";"Adenine salvage";"Neutrophil degranulation";"Purine salvage";"Glyphosate degradation III"
OTAU006356-PA	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
OTAU010458-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
OTAU012540-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU002875-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU007510-PA	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
OTAU001642-PA	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
OTAU001140-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU014921-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU001033-PA	9	KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I"
OTAU011353-PA	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
OTAU007652-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
OTAU009129-PA	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
OTAU009356-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU008455-PA	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
OTAU015899-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU001632-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU001297-PA	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
OTAU011812-PA	7	MetaCyc: PWY-5686;MetaCyc: PWY-7791;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7790	"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis II"
OTAU013553-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU007503-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
OTAU007739-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU006315-PA	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
OTAU003912-PA	26	Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239	"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1"
OTAU009487-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
OTAU000080-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
OTAU013111-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
OTAU013910-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU001567-PA	5	Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787	"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state"
OTAU006093-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
OTAU016198-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
OTAU008654-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU016584-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU000873-PA	19	MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;Reactome: R-HSA-71403;Reactome: R-HSA-70263;MetaCyc: PWY-7115;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37	"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Citric acid cycle (TCA cycle)";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism"
OTAU002141-PA	5	MetaCyc: PWY-7560;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7	"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis"
OTAU003860-PA	17	Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
OTAU013932-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU000091-PA	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
OTAU008454-PA	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
OTAU014162-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU001682-PA	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
OTAU003456-PA	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
OTAU005549-PA	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
OTAU000645-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
OTAU008680-PA	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
OTAU013184-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
OTAU000063-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU000395-PA	29	Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-112382	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex"
OTAU001909-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
OTAU005728-PA	4	Reactome: R-HSA-391160;Reactome: R-HSA-216083;Reactome: R-HSA-6798695;Reactome: R-HSA-202733	"Signal regulatory protein family interactions";"Integrin cell surface interactions";"Neutrophil degranulation";"Cell surface interactions at the vascular wall"
OTAU009083-PA	3	Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Rap1 signalling";"Ca2+ pathway";"cGMP effects"
OTAU000381-PA	11	MetaCyc: PWY-5913;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7268;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-6728;MetaCyc: PWY-7124	"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)"
OTAU008860-PA	6	Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
OTAU012225-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU002706-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU003109-PA	7	Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6737	"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation V"
OTAU005876-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU015674-PA	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
OTAU007168-PA	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
OTAU006661-PA	15	Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944	"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2"
OTAU012025-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU000658-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
OTAU013886-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU006831-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU010797-PA	6	MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Candicidin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
OTAU012927-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU008361-PA	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
OTAU011343-PA	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
OTAU015000-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU011574-PA	17	MetaCyc: PWY-6611;MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-5532;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1	"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine catabolism";"Purine metabolism";"Adenine and adenosine salvage III";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism"
OTAU013447-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
OTAU005592-PA	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
OTAU003320-PA	19	Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038	"Regulation of TLR by endogenous ligand";"VLDL clearance";"Chylomicron remodeling";"Scavenging by Class H Receptors";"LDL remodeling";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Chylomicron assembly";"Scavenging by Class F Receptors";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Chylomicron clearance";"LDL clearance"
OTAU004488-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
OTAU012814-PA	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
OTAU003105-PA	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
OTAU006780-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU007214-PA	13	KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"Keratan sulfate degradation"
OTAU014103-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU008910-PA	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357	"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1"
OTAU014750-PA	15	MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042	"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Glycolysis IV (plant cytosol)"
OTAU014751-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
OTAU010724-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
OTAU014038-PA	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
OTAU002862-PA	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
OTAU001179-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU012271-PA	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
OTAU001023-PA	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
OTAU004410-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
OTAU001629-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU007257-PA	9	Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-6794361	"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins"
OTAU006873-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU010692-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU012984-PA	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
OTAU009000-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
OTAU003539-PA	4	Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"Syndecan interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
OTAU009549-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU015507-PA	4	Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
OTAU015488-PA	10	KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-6537;KEGG: 00410+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6535;Reactome: R-HSA-916853;MetaCyc: PWY-5022;KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321	"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II";"beta-Alanine metabolism";"Butanoate metabolism";"4-aminobutanoate degradation I";"Degradation of GABA";"4-aminobutanoate degradation V";"Propanoate metabolism";"L-glutamate degradation IV"
OTAU010323-PA	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
OTAU002703-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU003106-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU009016-PA	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
OTAU001234-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU013668-PA	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
OTAU000350-PA	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
OTAU015331-PA	1	Reactome: R-HSA-1483255	"PI Metabolism"
OTAU007497-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
OTAU012508-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
OTAU000804-PA	33	KEGG: 00982+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5480;MetaCyc: PWY-5057;MetaCyc: PWY-5082;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-1801;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-6313;MetaCyc: PWY-3162;MetaCyc: PWY-7798;KEGG: 00625+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-7013;MetaCyc: PWY-6871;MetaCyc: PWY-5078;MetaCyc: PWY-5076;MetaCyc: PWY-7111;MetaCyc: PWY-6342;MetaCyc: PWY-6587;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6333;Reactome: R-HSA-71384	"Drug metabolism - cytochrome P450";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Phenylethanol biosynthesis";"Methane metabolism";"Pyruvate fermentation to ethanol I";"L-valine degradation II";"L-methionine degradation III";"Retinol metabolism";"Pyruvate fermentation to ethanol II";"Formaldehyde oxidation II (glutathione-dependent)";"Glycolysis / Gluconeogenesis";"Butanol and isobutanol biosynthesis (engineered)";"Serotonin degradation";"L-tryptophan degradation V (side chain pathway)";"Protein S-nitrosylation and denitrosylation";"Chloroalkane and chloroalkene degradation";"Glycine, serine and threonine metabolism";"L-phenylalanine degradation III";"Naphthalene degradation";"Chitin degradation to ethanol";"Tyrosine metabolism";"Salidroside biosynthesis";"(S)-propane-1,2-diol degradation";"3-methylbutanol biosynthesis (engineered)";"L-isoleucine degradation II";"L-leucine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol III";"Metabolism of xenobiotics by cytochrome P450";"Acetaldehyde biosynthesis I";"Ethanol oxidation"
OTAU007491-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
OTAU003660-PA	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
OTAU006997-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
OTAU013464-PA	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
OTAU008516-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU011956-PA	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
OTAU000874-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU011794-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
OTAU005711-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU003389-PA	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway"
OTAU006250-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU003926-PA	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
OTAU005806-PA	16	KEGG: 00010+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-5723	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt"
OTAU002392-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU014092-PA	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
OTAU001243-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU001912-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
OTAU009573-PA	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
OTAU001622-PA	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
OTAU014552-PA	8	Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7199;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
OTAU009071-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
OTAU001936-PA	3	MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4	"Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis"
OTAU009553-PA	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
OTAU014148-PA	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
OTAU016158-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU009639-PA	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
OTAU016045-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
OTAU000603-PA	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
OTAU000632-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU009108-PA	29	Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5358606;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-3108214;Reactome: R-HSA-5656121;Reactome: R-HSA-174437;Reactome: R-HSA-3371511;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-912446;Reactome: R-HSA-5696397;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-5685938	"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by POLI";"Removal of the Flap Intermediate from the C-strand";"HSF1 activation";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"HDR through Single Strand Annealing (SSA)"
OTAU017058-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
OTAU007684-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
OTAU001775-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU008161-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
OTAU008829-PA	4	Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9614399	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors"
OTAU007735-PA	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
OTAU000082-PA	5	MetaCyc: PWY-6892;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism"
OTAU002012-PA	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
OTAU004061-PA	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
OTAU001035-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU008379-PA	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
OTAU012524-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU011045-PA	10	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape"
OTAU013554-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU013115-PA	14	Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210	"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER"
OTAU006403-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU009498-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
OTAU009524-PA	37	Reactome: R-HSA-204005;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-9639288;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-180910	"COPII-mediated vesicle transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"HCMV Late Events";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Amino acids regulate mTORC1";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs"
OTAU017130-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU002409-PA	3	Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676	"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle"
OTAU015115-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU013482-PA	12	KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-8051	"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Anandamide biosynthesis I"
OTAU002106-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU013850-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU004092-PA	26	Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-1362277;Reactome: R-HSA-69183;Reactome: R-HSA-5358565;Reactome: R-HSA-4615885;Reactome: R-HSA-8866654;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-69205;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-6804114;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"SUMOylation of DNA replication proteins";"E3 ubiquitin ligases ubiquitinate target proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"G1/S-Specific Transcription";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
OTAU006901-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU011235-PA	9	MetaCyc: PWY-241;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
OTAU001899-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU003622-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU002648-PA	4	Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
OTAU005547-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
OTAU010712-PA	10	MetaCyc: PWY-4661;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6365;MetaCyc: PWY-6366;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
OTAU006124-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU008166-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU004668-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU001171-PA	6	KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
OTAU000182-PA	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
OTAU017023-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU004290-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU014828-PA	6	Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
OTAU016596-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
OTAU017404-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU003981-PA	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
OTAU011477-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
OTAU000988-PA	5	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-8948751;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT"
OTAU009729-PA	13	Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
OTAU000971-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU011604-PA	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
OTAU012030-PA	1	Reactome: R-HSA-977347	"Serine biosynthesis"
OTAU016795-PA	29	Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167160	"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
OTAU000261-PA	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250	"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis"
OTAU016241-PA	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
OTAU007427-PA	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU004318-PA	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
OTAU002981-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
OTAU001365-PA	16	Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-194840;Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-1433557;Reactome: R-HSA-912526	"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"RET signaling";"Rho GTPase cycle";"Interleukin-7 signaling";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling"
OTAU011966-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU006044-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
OTAU007876-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
OTAU010659-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU005829-PA	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
OTAU014124-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU013874-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
OTAU001357-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU003050-PA	14	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-69091	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Polymerase switching"
OTAU007614-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
OTAU011615-PA	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
OTAU002775-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
OTAU009454-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU003931-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU000442-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU005492-PA	1	Reactome: R-HSA-912446	"Meiotic recombination"
OTAU005759-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
OTAU000299-PA	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
OTAU004278-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU001423-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU006922-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU003535-PA	16	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
OTAU008103-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU003369-PA	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
OTAU014352-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU000371-PA	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
OTAU007371-PA	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
OTAU010331-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
OTAU012933-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU009837-PA	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
OTAU002223-PA	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
OTAU001506-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU009353-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU010299-PA	1	Reactome: R-HSA-5617833	"Cilium Assembly"
OTAU005206-PA	8	KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6609	"Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine salvage";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III"
OTAU003823-PA	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate"
OTAU002256-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU004382-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
OTAU009243-PA	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
OTAU011782-PA	5	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005	"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport"
OTAU011413-PA	6	KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403	"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)"
OTAU001657-PA	3	Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
OTAU013435-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
OTAU005420-PA	13	MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969	"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
OTAU010917-PA	10	MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-5484	"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)"
OTAU011880-PA	5	Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
OTAU011892-PA	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
OTAU016437-PA	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism"
OTAU014141-PA	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
OTAU000142-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU011463-PA	9	Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827	"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
OTAU008627-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU007043-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU017312-PA	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
OTAU001488-PA	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
OTAU009116-PA	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
OTAU011879-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
OTAU010358-PA	22	MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-5353;MetaCyc: PWY-7728;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7053;MetaCyc: PWY-7049;MetaCyc: PWY-6433;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6958;MetaCyc: PWY-7724;MetaCyc: PWY-7726;MetaCyc: PWY-5080	"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis I"
OTAU005065-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
OTAU015267-PA	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
OTAU001414-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
OTAU006680-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
OTAU002060-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU013117-PA	14	Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5696400	"Translesion synthesis by POLI";"Polymerase switching";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Dual Incision in GG-NER"
OTAU008214-PA	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
OTAU011400-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU002812-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU010044-PA	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
OTAU015897-PA	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
OTAU013825-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
OTAU005560-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU012751-PA	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
OTAU007518-PA	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
OTAU005769-PA	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
OTAU004839-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU002092-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
OTAU001848-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU003266-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
OTAU009873-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
OTAU010752-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU000290-PA	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
OTAU015052-PA	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
OTAU003459-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
OTAU014334-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU016076-PA	24	Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861	"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly"
OTAU013240-PA	9	Reactome: R-HSA-446193;MetaCyc: PWY-6385;MetaCyc: PWY-5265;MetaCyc: PWY-6471;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;KEGG: 00513+2.4.1.141;KEGG: 00510+2.4.1.141	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
OTAU004118-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU007659-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
OTAU000977-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU011783-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU014551-PA	20	Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-1257604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1	"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"Thermogenesis";"Macroautophagy";"Regulation of PTEN gene transcription";"Human papillomavirus infection";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"mTOR signalling";"mTOR signaling pathway";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection"
OTAU011440-PA	5	Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-165159	"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling"
OTAU009486-PA	12	Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
OTAU001327-PA	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
OTAU006844-PA	4	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
OTAU000831-PA	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829	"Aggrephagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy"
OTAU000366-PA	6	KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22	"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions"
OTAU001384-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU010438-PA	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
OTAU004596-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
OTAU012239-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript"
OTAU006840-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU005328-PA	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
OTAU016426-PA	6	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
OTAU006896-PA	12	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
OTAU017103-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
OTAU004388-PA	5	MetaCyc: PWY-7766;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
OTAU001876-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
OTAU012571-PA	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
OTAU005294-PA	11	Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631	"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility"
OTAU000741-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU012447-PA	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
OTAU010658-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU005634-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
OTAU012304-PA	23	Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-420092	"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"Glucagon-type ligand receptors"
OTAU009750-PA	3	Reactome: R-HSA-5576890;Reactome: R-HSA-1296072;Reactome: R-HSA-5576893	"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels";"Phase 2 - plateau phase"
OTAU014260-PA	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
OTAU011223-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU014525-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU002987-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU008226-PA	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
OTAU007729-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
OTAU008813-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
OTAU007703-PA	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
OTAU015712-PA	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2	"Photosynthesis";"Ion channel transport";"Insulin receptor recycling";"ATP biosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Oxidative phosphorylation"
OTAU006052-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU013639-PA	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
OTAU007201-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU012402-PA	26	Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436	"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"Kinesins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic"
OTAU007472-PA	6	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway"
OTAU002133-PA	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
OTAU003207-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU005529-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU008584-PA	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)"
OTAU003112-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU010059-PA	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
OTAU001176-PA	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway"
OTAU007580-PA	13	MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-5913	"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)"
OTAU006803-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
OTAU004161-PA	7	MetaCyc: PWY-2161;MetaCyc: PWY-1722;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841	"Folate polyglutamylation";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)"
OTAU015637-PA	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
OTAU008452-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
OTAU014152-PA	5	Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168	"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)"
OTAU002808-PA	5	KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536;Reactome: R-HSA-189451	"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis"
OTAU003420-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
OTAU005632-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU008196-PA	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
OTAU002713-PA	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU014754-PA	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
OTAU003855-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU009165-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU007348-PA	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
OTAU003165-PA	9	Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096	"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation"
OTAU017376-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
OTAU007563-PA	7	KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;MetaCyc: PWY-6351;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis"
OTAU005630-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU002889-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
OTAU005094-PA	1	Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH2"
OTAU001750-PA	57	Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-8951664	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Neutrophil degranulation";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation"
OTAU005882-PA	4	Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
OTAU001048-PA	14	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-975634;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen degradation";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism"
OTAU009814-PA	29	Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-167200	"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
OTAU010916-PA	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
OTAU009461-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU012276-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU013799-PA	6	Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
OTAU014738-PA	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-114608	"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation"
OTAU001663-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
OTAU009743-PA	17	MetaCyc: PWY-5532;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;MetaCyc: PWY-4202;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-6609;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1	"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage III";"Purine catabolism";"Purine metabolism"
OTAU009227-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU004078-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
OTAU006009-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
OTAU006188-PA	1	Reactome: R-HSA-1296061	"HCN channels"
OTAU012824-PA	10	Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693616	"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange"
OTAU008633-PA	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
OTAU010542-PA	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
OTAU008114-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU013335-PA	16	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation"
OTAU001955-PA	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
OTAU006726-PA	6	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation"
OTAU005029-PA	5	Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling"
OTAU009068-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
OTAU003296-PA	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
OTAU000692-PA	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
OTAU005902-PA	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
OTAU004578-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU000629-PA	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
OTAU006628-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU010154-PA	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
OTAU007366-PA	56	Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5689603	"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"UCH proteinases"
OTAU000084-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
OTAU012522-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU015117-PA	4	KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
OTAU016494-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU007399-PA	1	Reactome: R-HSA-419771	"Opsins"
OTAU014155-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
OTAU013982-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU007914-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU010829-PA	1	Reactome: R-HSA-977443	"GABA receptor activation"
OTAU003295-PA	5	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
OTAU000805-PA	5	KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012;MetaCyc: PWY-6289;MetaCyc: PWY-6012-1;Reactome: R-HSA-199220	"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism";"Petrobactin biosynthesis";"Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism"
OTAU003300-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU006262-PA	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
OTAU005465-PA	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
OTAU007728-PA	22	MetaCyc: PWY-7606;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-7726;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6958;MetaCyc: PWY-7602;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7053;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7601	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
OTAU006272-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
OTAU014528-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU011424-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
OTAU005633-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU007916-PA	18	KEGG: 00020+1.8.1.4;Reactome: R-HSA-204174;KEGG: 00380+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70895;MetaCyc: PWY-5084;Reactome: R-HSA-6783984;Reactome: R-HSA-389661;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-71403;Reactome: R-HSA-71064;KEGG: 00280+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4;MetaCyc: PWY-5046	"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tryptophan metabolism";"Glycine, serine and threonine metabolism";"Branched-chain amino acid catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine degradation";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Citric acid cycle (TCA cycle)";"Lysine catabolism";"Valine, leucine and isoleucine degradation";"Pyruvate metabolism";"Lysine degradation";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA"
OTAU001659-PA	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
OTAU006911-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU001816-PA	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
OTAU010851-PA	4	Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
OTAU004194-PA	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
OTAU008862-PA	6	Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
OTAU004875-PA	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
OTAU012149-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
OTAU006347-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU014217-PA	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6598	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis"
OTAU003953-PA	16	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
OTAU006392-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
OTAU005544-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU004917-PA	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
OTAU011715-PA	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
OTAU007711-PA	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins"
OTAU000580-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU010947-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU004000-PA	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
OTAU003930-PA	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
OTAU011337-PA	14	MetaCyc: PWY-5690;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-4302	"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)"
OTAU003542-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU003874-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
OTAU001994-PA	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
OTAU003572-PA	8	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-113507	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
OTAU008635-PA	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
OTAU002755-PA	7	KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4;Reactome: R-HSA-77111;Reactome: R-HSA-9033241;MetaCyc: PWY-5074	"Geraniol degradation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Synthesis of Ketone Bodies";"Peroxisomal protein import";"Mevalonate degradation"
OTAU006868-PA	16	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Translation initiation complex formation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
OTAU017272-PA	6	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
OTAU008277-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU003088-PA	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
OTAU015534-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU011617-PA	16	Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
OTAU014072-PA	9	MetaCyc: PWY-7115;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
OTAU014331-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU016161-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU012221-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU003037-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU002963-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU000555-PA	1	Reactome: R-HSA-1483191	"Synthesis of PC"
OTAU016359-PA	11	KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187	"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
OTAU011703-PA	3	Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate"
OTAU000921-PA	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
OTAU004505-PA	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
OTAU006004-PA	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
OTAU002074-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU002969-PA	7	Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
OTAU014102-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU002702-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU016306-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU014855-PA	18	MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7409	"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
OTAU001962-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU003284-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
OTAU008336-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU005601-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU000234-PA	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
OTAU014880-PA	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
OTAU001250-PA	5	Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU001760-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU000965-PA	1	MetaCyc: PWY-6938	"NADH repair"
OTAU004432-PA	9	KEGG: 00480+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18	"Glutathione metabolism";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450"
OTAU002305-PA	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
OTAU013026-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU007218-PA	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
OTAU001137-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU011839-PA	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
OTAU005417-PA	5	Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU013917-PA	26	Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-210744	"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"Attenuation phase";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
OTAU001388-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
OTAU009557-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU003858-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
OTAU009375-PA	9	Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-1362277;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-69017	"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6"
OTAU014327-PA	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
OTAU013834-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
OTAU003424-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
OTAU009920-PA	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
OTAU009079-PA	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
OTAU015100-PA	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
OTAU011060-PA	8	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;MetaCyc: PWY-7979	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)"
OTAU000980-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU005119-PA	1	Reactome: R-HSA-203615	"eNOS activation"
OTAU003093-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU008142-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU006090-PA	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
OTAU007718-PA	3	Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320	"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH"
OTAU000303-PA	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
OTAU015520-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU010091-PA	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
OTAU011279-PA	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
OTAU006359-PA	7	Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
OTAU006264-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
OTAU001863-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
OTAU000841-PA	5	Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-186763	"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Downstream signal transduction"
OTAU012773-PA	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
OTAU007333-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
OTAU012433-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU014361-PA	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU007827-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
OTAU008102-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU011628-PA	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
OTAU012894-PA	7	Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism"
OTAU016220-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU008631-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU016070-PA	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-162710;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Synthesis of glycosylphosphatidylinositol (GPI)";"Amino sugar and nucleotide sugar metabolism"
OTAU015329-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU012228-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU007058-PA	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214	"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
OTAU011304-PA	21	MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7198;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7205	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"CMP phosphorylation"
OTAU014492-PA	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
OTAU007939-PA	8	Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-113507	"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
OTAU011376-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU013155-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
OTAU000125-PA	15	Reactome: R-HSA-975957;Reactome: R-HSA-1650814;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-186797;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-8948216;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Signaling by PDGF";"ECM proteoglycans";"Extracellular matrix organization";"NCAM1 interactions";"Collagen chain trimerization";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Laminin interactions";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
OTAU014401-PA	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
OTAU008212-PA	5	Reactome: R-HSA-5685939;Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210	"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
OTAU013677-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU004298-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU001919-PA	17	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU000918-PA	3	Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198	"Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis"
OTAU005261-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU013824-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU008469-PA	5	Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-211945	"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Endogenous sterols";"Phase I - Functionalization of compounds"
OTAU007042-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU007951-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU013248-PA	7	MetaCyc: PWY-4984;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-31;MetaCyc: PWY-46	"Urea cycle";"Arginine biosynthesis";"Urea cycle";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Putrescine biosynthesis III"
OTAU000890-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU015462-PA	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
OTAU002952-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU015077-PA	6	KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-6527	"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Stachyose degradation"
OTAU008792-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU005561-PA	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
OTAU001168-PA	4	KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
OTAU002976-PA	5	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA"
OTAU007046-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
OTAU005906-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
OTAU010963-PA	7	Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
OTAU013123-PA	57	Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050	"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
OTAU015927-PA	16	Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
OTAU003617-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU009872-PA	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
OTAU007754-PA	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
OTAU009032-PA	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
OTAU001952-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
OTAU010911-PA	3	Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129	"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)"
OTAU000425-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
OTAU011636-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU011005-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU010871-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-2142789	"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquinol biosynthesis"
OTAU012292-PA	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
OTAU003788-PA	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043	"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
OTAU002286-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU013032-PA	14	MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-1268020;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5	"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes"
OTAU009463-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU003342-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
OTAU013672-PA	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
OTAU014259-PA	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
OTAU003913-PA	26	Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU011397-PA	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110328	"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Packaging Of Telomere Ends";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
OTAU003741-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU009531-PA	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
OTAU015346-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU004490-PA	3	Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330	"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine"
OTAU008128-PA	15	MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40	"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism"
OTAU010012-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU005557-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
OTAU017208-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU005120-PA	1	Reactome: R-HSA-203615	"eNOS activation"
OTAU007846-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU002720-PA	5	KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667;MetaCyc: PWY-5981	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III"
OTAU008179-PA	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
OTAU008073-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU008402-PA	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
OTAU015248-PA	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
OTAU001838-PA	7	Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724	"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription"
OTAU016911-PA	14	MetaCyc: PWY-7279;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00650+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-3781;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1	"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Butanoate metabolism";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes"
OTAU007898-PA	5	Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
OTAU012137-PA	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
OTAU002727-PA	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
OTAU001762-PA	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
OTAU016452-PA	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
OTAU013822-PA	8	Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
OTAU004534-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU010393-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
OTAU010386-PA	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU012507-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
OTAU002291-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU003606-PA	13	MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-4061;MetaCyc: PWY-7533	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis"
OTAU006215-PA	7	KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301	"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis"
OTAU005419-PA	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
OTAU013326-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU017371-PA	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
OTAU006918-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU012327-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
OTAU008629-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU000593-PA	1	Reactome: R-HSA-3295583	"TRP channels"
OTAU013430-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
OTAU011769-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU014395-PA	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
OTAU002255-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
OTAU016085-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU002604-PA	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
OTAU005047-PA	9	Reactome: R-HSA-70263;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-5484	"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)"
OTAU003228-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
OTAU008021-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU009263-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU014842-PA	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
OTAU009166-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU008589-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU007642-PA	40	Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-167200;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167152	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat"
OTAU015513-PA	8	KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7197	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation"
OTAU001783-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
OTAU004778-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU001574-PA	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210	"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER"
OTAU007278-PA	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
OTAU016438-PA	31	MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-5994;MetaCyc: PWY-6113;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-7388;Reactome: R-HSA-75105;MetaCyc: PWY-5971;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-7664;MetaCyc: PWY-7858;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-6519;Reactome: R-HSA-163765;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-6799;MetaCyc: PWY-7663;MetaCyc: PWY-8047	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis"
OTAU004129-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU012488-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU007101-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU002726-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU000565-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
OTAU014121-PA	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
OTAU011770-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU002193-PA	7	Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268	"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism"
OTAU004286-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU001575-PA	14	KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-5497;MetaCyc: PWY-181;MetaCyc: PWY-3661;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;MetaCyc: PWY-1622;KEGG: 00680+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00670+2.1.2.1;KEGG: 00630+2.1.2.1	"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Photorespiration ";"Glycine betaine degradation I";"Metabolism of folate and pterines";"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"One carbon pool by folate";"Glyoxylate and dicarboxylate metabolism"
OTAU006485-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
OTAU013136-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
OTAU001672-PA	16	Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX"
OTAU009704-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
OTAU012062-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU009783-PA	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
OTAU005302-PA	13	MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7384	"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
OTAU017156-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU002695-PA	8	Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68952	"Processive synthesis on the lagging strand";"Polymerase switching";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation"
OTAU001403-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
OTAU002815-PA	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
OTAU000008-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU016645-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU002534-PA	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
OTAU002847-PA	1	Reactome: R-HSA-200425	"Carnitine metabolism"
OTAU009314-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
OTAU000666-PA	5	Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604	"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling"
OTAU002607-PA	5	KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Triglyceride biosynthesis";"Glycerolipid metabolism"
OTAU013154-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
OTAU009827-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
OTAU013118-PA	1	Reactome: R-HSA-3295583	"TRP channels"
OTAU004095-PA	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
OTAU004474-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
OTAU005414-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
OTAU003605-PA	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
OTAU003455-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
OTAU012171-PA	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
OTAU003685-PA	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
OTAU008796-PA	10	KEGG: 00020+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6549	"Citrate cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"L-glutamine biosynthesis III"
OTAU008733-PA	24	Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-114604;Reactome: R-HSA-2871837;Reactome: R-HSA-9634635;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;Reactome: R-HSA-444257;Reactome: R-HSA-2730905;Reactome: R-HSA-202424;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-354192	"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"GPVI-mediated activation cascade";"FCERI mediated NF-kB activation";"Estrogen-stimulated signaling through PRKCZ";"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"Regulation of TP53 Degradation";"Human papillomavirus infection";"CLEC7A (Dectin-1) signaling";"Activation of AKT2";"PIP3 activates AKT signaling";"Thermogenesis";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"RSK activation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Downstream TCR signaling";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Integrin signaling"
OTAU010510-PA	1	Reactome: R-HSA-70263	"Gluconeogenesis"
OTAU000133-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
OTAU005023-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU015981-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
OTAU000252-PA	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
OTAU007373-PA	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
OTAU000289-PA	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
OTAU015006-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
OTAU003880-PA	11	Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
OTAU000824-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU013090-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU000716-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU009811-PA	7	Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288	"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1"
OTAU010092-PA	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
OTAU002000-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU002498-PA	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
OTAU003256-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU005472-PA	3	Reactome: R-HSA-429947;Reactome: R-HSA-5617472;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
OTAU013852-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
OTAU005555-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU005462-PA	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
OTAU000090-PA	4	Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753	"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions"
OTAU006954-PA	8	KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5269;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;KEGG: 04658+3.1.3.16;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Synthesis of PG";"Th1 and Th2 cell differentiation";"Type I lipoteichoic acid biosynthesis (S. aureus)"
OTAU007484-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU015489-PA	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
OTAU003676-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU010992-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
OTAU009143-PA	7	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-2173795	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity"
OTAU000491-PA	4	Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906	"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
OTAU015022-PA	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
OTAU006894-PA	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis"
OTAU011061-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
OTAU013086-PA	4	KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
OTAU004243-PA	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
OTAU011659-PA	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
OTAU009008-PA	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
OTAU015476-PA	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
OTAU009200-PA	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
OTAU013440-PA	52	Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-113418	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex"
OTAU004347-PA	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
OTAU000110-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
OTAU000667-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU006237-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU002940-PA	4	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
OTAU014740-PA	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
OTAU010264-PA	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
OTAU001950-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU008754-PA	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
OTAU006606-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU010996-PA	8	Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
OTAU013424-PA	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
OTAU002031-PA	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU001226-PA	7	MetaCyc: PWY-7839;MetaCyc: PWY-5129;Reactome: R-HSA-1660662;MetaCyc: PWY-7836;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838	"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis"
OTAU015953-PA	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
OTAU013437-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU010913-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU003759-PA	13	MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-7102	"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)"
OTAU012022-PA	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
OTAU007625-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
OTAU005588-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU007803-PA	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
OTAU000924-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
OTAU008119-PA	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
OTAU016905-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU003578-PA	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
OTAU011827-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU015189-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
OTAU009501-PA	27	Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377	"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"HCMV Early Events";"HCMV Late Events";"SUMOylation of SUMOylation proteins"
OTAU004905-PA	6	KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-6908	"Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)"
OTAU011017-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU003615-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU016272-PA	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
OTAU002122-PA	57	Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin"
OTAU016710-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU010421-PA	17	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
OTAU007879-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
OTAU002395-PA	8	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
OTAU004060-PA	29	Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-77075	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE"
OTAU009450-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU008260-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
OTAU004022-PA	17	Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430	"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex"
OTAU000835-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU004292-PA	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
OTAU002382-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU005844-PA	13	MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-7254;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-561	"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"Pyruvate metabolism";"Reductive TCA cycle II";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation"
OTAU007931-PA	56	Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-382556	"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Degradation of AXIN";"ABC-family proteins mediated transport"
OTAU013137-PA	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
OTAU007915-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU010201-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
OTAU012420-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU014041-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU002954-PA	22	Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558	"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
OTAU005579-PA	9	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"PI3K-Akt signaling pathway"
OTAU001652-PA	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
OTAU016267-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU015956-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
OTAU013804-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
OTAU003151-PA	11	MetaCyc: PWY-7124;MetaCyc: PWY-6549;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913	"Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)"
OTAU011275-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU005104-PA	6	Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-2173788;MetaCyc: PWY-7511;Reactome: R-HSA-8948751	"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling";"Protein ubiquitination";"Regulation of PTEN stability and activity"
OTAU008023-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
OTAU003684-PA	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
OTAU000017-PA	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
OTAU013550-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU001627-PA	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
OTAU001756-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
OTAU007993-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
OTAU003527-PA	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
OTAU001385-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
OTAU000129-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
OTAU005869-PA	6	Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination"
OTAU004028-PA	17	Reactome: R-HSA-3270619;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-1834949;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554	"IRF3-mediated induction of type I IFN";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cytosolic sensors of pathogen-associated DNA";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
OTAU010668-PA	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
OTAU002988-PA	2	KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19	"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis"
OTAU005816-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU013108-PA	1	Reactome: R-HSA-1483148	"Synthesis of PG"
OTAU005259-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU008198-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
OTAU006685-PA	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438	"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic"
OTAU010322-PA	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
OTAU006068-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU010279-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
OTAU013676-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU011800-PA	15	Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243	"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery"
OTAU005985-PA	3	Reactome: R-HSA-73614;MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyrimidine salvage";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
OTAU000871-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU015974-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU007305-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU002462-PA	30	Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-2564830;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-73779	"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Cytosolic iron-sulfur cluster assembly";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
OTAU006213-PA	10	Reactome: R-HSA-9027276;KEGG: 04070+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 00562+2.7.1.153	"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Inositol phosphate metabolism"
OTAU015119-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
OTAU010933-PA	10	KEGG: 00130+2.1.1.163;MetaCyc: PWY-5849;MetaCyc: PWY-5895;MetaCyc: PWY-5844;MetaCyc: PWY-5891;MetaCyc: PWY-5890;Reactome: R-HSA-2142789;MetaCyc: PWY-5892;MetaCyc: PWY-5839;MetaCyc: PWY-7996	"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-10 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-4 biosynthesis I"
OTAU007327-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU009651-PA	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
OTAU006368-PA	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
OTAU007222-PA	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
OTAU000148-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
OTAU002440-PA	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
OTAU000162-PA	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
OTAU002269-PA	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
OTAU001236-PA	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
OTAU002651-PA	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
OTAU000300-PA	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
OTAU004267-PA	7	KEGG: 00330+3.5.3.1;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-4984;MetaCyc: PWY-46;MetaCyc: PWY-6922;MetaCyc: PWY-31	"Arginine and proline metabolism";"Arginine biosynthesis";"Urea cycle";"Urea cycle";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation"
OTAU007369-PA	1	Reactome: R-HSA-189451	"Heme biosynthesis"
OTAU012127-PA	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
OTAU012869-PA	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
OTAU001344-PA	11	Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007	"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events"
OTAU000384-PA	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
OTAU002564-PA	3	KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
OTAU001866-PA	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
OTAU001377-PA	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
OTAU007756-PA	10	Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-427413	"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression"
OTAU013773-PA	3	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway"
OTAU007968-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU009688-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU004193-PA	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
OTAU007569-PA	14	MetaCyc: PWY-6728;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-3781;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-7254;Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1	"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Citrate cycle (TCA cycle)"
OTAU015651-PA	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
OTAU010689-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU012975-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
OTAU004863-PA	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
OTAU012227-PA	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
OTAU000610-PA	11	Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation"
OTAU015521-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU003185-PA	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
OTAU016307-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
OTAU000455-PA	11	MetaCyc: PWY-6964;Reactome: R-HSA-210455;MetaCyc: PWY-6549;MetaCyc: PWY-381;Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2	"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism"
OTAU009041-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
OTAU001691-PA	6	MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166	"Cardiolipin biosynthesis I";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA"
OTAU003378-PA	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
OTAU015901-PA	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
OTAU015823-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU017191-PA	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
OTAU014549-PA	20	Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1	"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription";"Macroautophagy";"Thermogenesis";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"mTOR signaling pathway";"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of TP53 Degradation";"Human papillomavirus infection"
OTAU001186-PA	24	Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833	"Gap junction assembly";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly"
OTAU002352-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
OTAU004617-PA	6	MetaCyc: PWY-6906;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-7077	"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation"
OTAU011009-PA	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
OTAU009082-PA	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
OTAU008526-PA	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
OTAU016427-PA	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU015236-PA	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
OTAU002673-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU013643-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU001610-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU009267-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU007940-PA	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
OTAU000799-PA	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
OTAU005554-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU014029-PA	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
OTAU016454-PA	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
OTAU006913-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
OTAU010777-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU008503-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
OTAU011040-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU009638-PA	3	Reactome: R-HSA-73772;Reactome: R-HSA-8953750;Reactome: R-HSA-427389	"RNA Polymerase I Promoter Escape";"Transcriptional Regulation by E2F6";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
OTAU006534-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU000635-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU010965-PA	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
OTAU005415-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU008669-PA	3	Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
OTAU015928-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
OTAU003098-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU004197-PA	9	Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
OTAU003293-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU011890-PA	1	Reactome: R-HSA-5676934	"Protein repair"
OTAU005831-PA	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
OTAU009781-PA	4	KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26	"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
OTAU002699-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU007612-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU001580-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
OTAU016843-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU001479-PA	5	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
OTAU007173-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
OTAU010742-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU004924-PA	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)"
OTAU001132-PA	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
OTAU011003-PA	18	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-166208	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"mTORC1-mediated signalling"
OTAU016765-PA	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
OTAU006849-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
OTAU010690-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU012947-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
OTAU006529-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
OTAU014156-PA	4	KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
OTAU003618-PA	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
OTAU008086-PA	26	Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-389977	"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway"
OTAU013901-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
OTAU001533-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
OTAU010493-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU007628-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
OTAU008126-PA	15	MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40	"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Purine metabolism"
OTAU010024-PA	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
OTAU016504-PA	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU004418-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU012683-PA	6	Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
OTAU000043-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
OTAU002274-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU006652-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
OTAU013333-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU015247-PA	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
OTAU003561-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU008242-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU011094-PA	3	Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
OTAU001920-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
OTAU002259-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
OTAU007240-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
OTAU004422-PA	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
OTAU001780-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU014390-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU017095-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
OTAU000661-PA	7	KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-8964208;Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134	"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine metabolism";"Folate biosynthesis";"L-tyrosine biosynthesis IV"
OTAU002415-PA	3	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins"
OTAU004861-PA	17	Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-5656169	"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Polymerase switching";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis"
OTAU010318-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU012893-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU011038-PA	3	Reactome: R-HSA-8939902;Reactome: R-HSA-6785807;Reactome: R-HSA-8878166	"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2"
OTAU009641-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU012310-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
OTAU002970-PA	57	Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-532668;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids"
OTAU017049-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU004274-PA	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
OTAU015034-PA	58	Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-382556	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"Hedgehog 'on' state";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"UCH proteinases";"Metalloprotease DUBs";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"ABC-family proteins mediated transport"
OTAU009774-PA	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
OTAU015862-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
OTAU012269-PA	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
OTAU011523-PA	12	MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5870	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
OTAU001987-PA	1	Reactome: R-HSA-419037	"NCAM1 interactions"
OTAU013298-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU002575-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
OTAU014840-PA	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
OTAU017411-PA	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695;Reactome: R-HSA-499943;Reactome: R-HSA-2162123	"Arachidonic acid metabolism";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
OTAU007857-PA	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
OTAU007865-PA	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
OTAU001731-PA	1	Reactome: R-HSA-1296061	"HCN channels"
OTAU002203-PA	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
OTAU012897-PA	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
OTAU007891-PA	12	Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
OTAU001427-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU007599-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
OTAU004555-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU001167-PA	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
OTAU008653-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU009884-PA	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
OTAU010049-PA	16	Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
OTAU014261-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU012449-PA	1	Reactome: R-HSA-114608	"Platelet degranulation"
OTAU002834-PA	11	Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-975634	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Syndecan interactions";"Retinoid metabolism and transport"
OTAU010960-PA	7	Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
OTAU008384-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU015070-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
OTAU000164-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU008477-PA	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
OTAU000707-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU002042-PA	30	Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-6796648;Reactome: R-HSA-6803204;Reactome: R-HSA-69541;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;Reactome: R-HSA-216083;Reactome: R-HSA-6804756;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-6803207;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-349425;Reactome: R-HSA-6804760;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693554	"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of DNA Repair Genes";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Stabilization of p53";"Thermogenesis";"PI3K-Akt signaling pathway";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"Integrin cell surface interactions";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Degradation";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Relaxin signaling pathway";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human cytomegalovirus infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of TP53 Activity through Methylation";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
OTAU002398-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
OTAU005534-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
OTAU000653-PA	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
OTAU005221-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU007357-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU000552-PA	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
OTAU011972-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU010843-PA	7	Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-373753	"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Nephrin family interactions"
OTAU016222-PA	14	MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8051	"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I"
OTAU017401-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU014493-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
OTAU006827-PA	9	Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER"
OTAU008197-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU000797-PA	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
OTAU001694-PA	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
OTAU006185-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU017093-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
OTAU002251-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU009299-PA	24	Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5663220	"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Kinesins";"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"HCMV Early Events";"Gap junction assembly";"RHO GTPases Activate Formins"
OTAU002307-PA	9	MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-8052	"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis"
OTAU001910-PA	10	Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111463	"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs"
OTAU015475-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
OTAU005779-PA	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1"
OTAU007784-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU013649-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU006863-PA	3	MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590	"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation"
OTAU012128-PA	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU005518-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
OTAU014826-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state"
OTAU015484-PA	5	Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;MetaCyc: PWY-7782	"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis"
OTAU002548-PA	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
OTAU012823-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU011762-PA	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
OTAU001301-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU013761-PA	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
OTAU001211-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU004163-PA	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
OTAU005483-PA	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
OTAU015788-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU002020-PA	7	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs"
OTAU017010-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
OTAU005197-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU009246-PA	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
OTAU009713-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU008352-PA	3	MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12	"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
OTAU007675-PA	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
OTAU014321-PA	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
OTAU000564-PA	5	Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381	"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
OTAU007139-PA	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
OTAU010374-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU007632-PA	4	Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-210991	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Basigin interactions"
OTAU007247-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU005199-PA	13	MetaCyc: PWY-5030;MetaCyc: PWY-2161;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841	"L-histidine degradation III";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Folate transformations I";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Folate transformations II (plants)"
OTAU000246-PA	57	Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751	"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"Hedgehog 'on' state";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity"
OTAU000929-PA	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
OTAU000761-PA	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
OTAU013343-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
OTAU014317-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
OTAU000820-PA	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion"
OTAU003232-PA	27	Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-159236	"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
OTAU003943-PA	11	KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7790;KEGG: 00240+2.1.3.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686;MetaCyc: PWY-7400	"Pyrimidine metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)"
OTAU013332-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
OTAU001716-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU011973-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU010998-PA	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
OTAU012920-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU012248-PA	3	Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases"
OTAU004932-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU009272-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
OTAU013611-PA	1	Reactome: R-HSA-71262	"Carnitine synthesis"
OTAU006339-PA	52	Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-69481	"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Degradation of AXIN";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints"
OTAU002837-PA	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
OTAU011809-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU013730-PA	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
OTAU012098-PA	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-114608	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation"
OTAU014530-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
OTAU004486-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
OTAU003777-PA	17	Reactome: R-HSA-167242;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287	"Abortive elongation of HIV-1 transcript in the absence of Tat";"T cell receptor signaling pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery"
OTAU013517-PA	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
OTAU014453-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
OTAU009856-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU006860-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU000559-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU003183-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
OTAU015679-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
OTAU002587-PA	5	Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895	"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency"
OTAU003978-PA	14	MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
OTAU013806-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU000608-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU015970-PA	1	Reactome: R-HSA-8951664	"Neddylation"
OTAU002744-PA	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
OTAU011785-PA	4	KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801	"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion"
OTAU017449-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
OTAU009064-PA	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
OTAU002089-PA	56	Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-69481	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Degradation of AXIN";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints"
OTAU007508-PA	19	KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7383;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00270+1.1.1.37	"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Cysteine and methionine metabolism"
OTAU000141-PA	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
OTAU008310-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU001133-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU000981-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU007947-PA	19	Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-399719	"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Long-term potentiation";"RAF/MAP kinase cascade";"RAF activation";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors"
OTAU010675-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU010191-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU013988-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU016993-PA	13	Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
OTAU014258-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU012270-PA	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
OTAU014016-PA	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
OTAU006690-PA	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
OTAU009334-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
OTAU011505-PA	7	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
OTAU005482-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU000263-PA	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
OTAU006626-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
OTAU003656-PA	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
OTAU010584-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU007949-PA	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
OTAU011853-PA	6	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-416993	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors"
OTAU006028-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
OTAU011378-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU013460-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
OTAU002928-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
OTAU003586-PA	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
OTAU012158-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU006743-PA	8	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6798695	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation"
OTAU005664-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
OTAU002944-PA	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
OTAU003483-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
OTAU000266-PA	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
OTAU002567-PA	58	KEGG: 00592+4.2.1.17;KEGG: 00280+4.2.1.17;MetaCyc: PWY-5789;Reactome: R-HSA-77350;KEGG: 00720+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00650+4.2.1.17;Reactome: R-HSA-77346;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-6944;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17;KEGG: 00362+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-5109;MetaCyc: PWY-7401;KEGG: 00623+1.1.1.35;KEGG: 00410+4.2.1.17;Reactome: R-HSA-77285;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7726;Reactome: R-HSA-77305;Reactome: R-HSA-77310;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-7779;MetaCyc: PWY-6435;MetaCyc: PWY-6863;Reactome: R-HSA-77348;MetaCyc: PWY-7654;Reactome: R-HSA-1482798;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;MetaCyc: PWY-6883;MetaCyc: PWY-5138;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583	"alpha-Linolenic acid metabolism";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Carbon fixation pathways in prokaryotes";"Fatty acid degradation";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Butanoate metabolism";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Caprolactam degradation";"Glutaryl-coa degradation";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Androstenedione degradation";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Tryptophan metabolism";"Fatty acid elongation";"Fatty acid elongation";"Geraniol degradation";"Butanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid salvage";"Lysine degradation";"Geraniol degradation";"Benzoate degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Toluene degradation";"beta-Alanine metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Phenylalanine metabolism";"Methyl ketone biosynthesis (engineered)";"Lysine degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Propanoate metabolism";"2-methylpropene degradation";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to hexanol (engineered)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Acyl chain remodeling of CL";"Tryptophan metabolism";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol I"
OTAU000059-PA	5	Reactome: R-HSA-8873719;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695	"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation"
OTAU003997-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
OTAU001887-PA	14	Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-141444;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-8854518;Reactome: R-HSA-2500257;Reactome: R-HSA-380259;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"AURKA Activation by TPX2";"Resolution of Sister Chromatid Cohesion";"Loss of Nlp from mitotic centrosomes";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
OTAU008609-PA	16	Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-176409	"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins"
OTAU001165-PA	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
OTAU002820-PA	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
OTAU016611-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
OTAU008185-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU006360-PA	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
OTAU006248-PA	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
OTAU017020-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU007039-PA	18	KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416	"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Anandamide biosynthesis I";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)"
OTAU003291-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU001644-PA	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
OTAU005955-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
OTAU003929-PA	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
OTAU010531-PA	3	Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway"
OTAU012185-PA	26	Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-9018519	"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"SUMOylation of transcription cofactors";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression"
OTAU007184-PA	11	Reactome: R-HSA-111457;Reactome: R-HSA-1268020;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111459	"Release of apoptotic factors from the mitochondria";"Mitochondrial protein import";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Regulation of the apoptosome activity";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage"
OTAU006316-PA	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
OTAU003761-PA	13	MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-5123	"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
OTAU011345-PA	14	MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-5972	"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)"
OTAU010835-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
OTAU002296-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
OTAU003558-PA	1	Reactome: R-HSA-71064	"Lysine catabolism"
OTAU009826-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
OTAU006809-PA	9	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
OTAU000418-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
OTAU006742-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
OTAU009604-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU010051-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU000901-PA	7	MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25	"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system"
OTAU008356-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU008207-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU007624-PA	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
OTAU016767-PA	11	Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-383280;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-212436	"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Nuclear Receptor transcription pathway";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway"
OTAU005058-PA	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
OTAU008168-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
OTAU000825-PA	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
OTAU008671-PA	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
OTAU013120-PA	6	Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273	"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis"
OTAU002721-PA	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
OTAU009593-PA	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
OTAU001882-PA	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
OTAU013245-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
OTAU008098-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU012089-PA	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
OTAU007556-PA	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis"
OTAU000990-PA	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
OTAU001051-PA	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
OTAU006724-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
OTAU007685-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
OTAU001257-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU013271-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU007045-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
OTAU008902-PA	26	Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606	"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"SUMOylation of transcription cofactors";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
OTAU015492-PA	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
OTAU000568-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
OTAU004964-PA	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
OTAU016551-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU005394-PA	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
OTAU001417-PA	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
OTAU012325-PA	5	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
OTAU015342-PA	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
OTAU013035-PA	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
OTAU001252-PA	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
OTAU012152-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
OTAU007010-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
OTAU001746-PA	6	MetaCyc: PWY-6854;Reactome: R-HSA-9615017;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505	"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
OTAU010924-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
OTAU001122-PA	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
OTAU005049-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU006547-PA	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
OTAU004167-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
OTAU013053-PA	2	Reactome: R-HSA-352230;Reactome: R-HSA-442660	"Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters"
OTAU010451-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
OTAU014138-PA	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
OTAU016869-PA	5	Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-3214841	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines"
OTAU002222-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU000256-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU005115-PA	2	Reactome: R-HSA-3065676;Reactome: R-HSA-3065678	"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
OTAU016594-PA	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
OTAU009153-PA	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
OTAU013661-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
OTAU011539-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU006622-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU008337-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU007113-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
OTAU005267-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU010495-PA	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
OTAU002101-PA	8	Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6783310;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Fanconi Anemia Pathway";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
OTAU001235-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU003265-PA	2	Reactome: R-HSA-3214847;Reactome: R-HSA-426486	"HATs acetylate histones";"Small interfering RNA (siRNA) biogenesis"
OTAU015817-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
OTAU015337-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU009998-PA	16	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
OTAU007135-PA	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
OTAU006128-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU013322-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU005584-PA	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
OTAU013101-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
OTAU016271-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
OTAU008148-PA	9	Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
OTAU000291-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU005697-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
OTAU007565-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU009313-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU016393-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state"
OTAU016210-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
OTAU017047-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU002616-PA	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
OTAU014405-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU004887-PA	14	MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis"
OTAU001911-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU004195-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU008209-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
OTAU007558-PA	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
OTAU010943-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU002880-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
OTAU009149-PA	6	Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265	"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes"
OTAU004209-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
OTAU000173-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU010274-PA	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
OTAU013039-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
OTAU010193-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU007943-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU001678-PA	6	Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
OTAU006225-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
OTAU016134-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
OTAU010672-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
OTAU014560-PA	6	Reactome: R-HSA-3371599;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism"
OTAU013902-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
OTAU012783-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
OTAU000306-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
OTAU004489-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU009571-PA	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)"
OTAU003864-PA	56	Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813	"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids"
OTAU017211-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU012583-PA	5	Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
OTAU009066-PA	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
OTAU012314-PA	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
OTAU008359-PA	12	Reactome: R-HSA-5362798;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-75893;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-982772;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-193692;Reactome: R-HSA-2660826	"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"TNF signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Growth hormone receptor signaling";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
OTAU004359-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
OTAU005233-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
OTAU010914-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU004165-PA	27	Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142	"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins"
OTAU005018-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU000560-PA	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
OTAU006605-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
OTAU006295-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU008961-PA	7	KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052	"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis"
OTAU008694-PA	6	Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)"
OTAU010459-PA	3	MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
OTAU009767-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU015628-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU003476-PA	14	Reactome: R-HSA-75109;MetaCyc: PWY-8052;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;Reactome: R-HSA-4419969	"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Synthesis of PE";"Ether lipid metabolism";"Synthesis of PC";"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina"
OTAU012860-PA	40	Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-167158	"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex"
OTAU011657-PA	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
OTAU006020-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU009912-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
OTAU001496-PA	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
OTAU008030-PA	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695	"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"Neutrophil degranulation"
OTAU001850-PA	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
OTAU008396-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
OTAU012338-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
OTAU007449-PA	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
OTAU007329-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU004509-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU005116-PA	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)"
OTAU011011-PA	9	MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16	"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Folate biosynthesis"
OTAU009858-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU009380-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU012117-PA	14	MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587	"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)"
OTAU002143-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
OTAU017247-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
OTAU010962-PA	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
OTAU005350-PA	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
OTAU004132-PA	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
OTAU010617-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
OTAU015952-PA	11	Reactome: R-HSA-200425;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1	"Carnitine metabolism";"Biotin transport and metabolism";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Pyruvate metabolism";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)"
OTAU009291-PA	5	MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;Reactome: R-HSA-196757	"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Metabolism of folate and pterines"
OTAU014057-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU006267-PA	6	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling"
OTAU013082-PA	5	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Formation of apoptosome";"Regulation of the apoptosome activity"
OTAU003876-PA	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
OTAU012842-PA	5	Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912420	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi"
OTAU011124-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
OTAU009206-PA	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
OTAU000722-PA	10	MetaCyc: PWY-4661;MetaCyc: PWY-6361;MetaCyc: PWY-6372;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
OTAU004051-PA	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
OTAU016817-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
OTAU004601-PA	9	MetaCyc: PWY-8086;Reactome: R-HSA-70263;Reactome: R-HSA-196780;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Biotin transport and metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency"
OTAU001700-PA	17	Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-4086398;Reactome: R-HSA-5689880;Reactome: R-HSA-937042	"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Ca2+ pathway";"Ub-specific processing proteases";"IRAK2 mediated activation of TAK1 complex"
OTAU003280-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU012544-PA	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
OTAU004077-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU000998-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
OTAU004430-PA	19	Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-8876725;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-3214858;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Protein methylation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Peptide chain elongation";"RMTs methylate histone arginines";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU003877-PA	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
OTAU010496-PA	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
OTAU015460-PA	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
OTAU000759-PA	4	KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
OTAU003383-PA	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
OTAU000840-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
OTAU011842-PA	8	Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
OTAU007645-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
OTAU015190-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU007653-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
OTAU014042-PA	6	MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17	"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Ascorbate and aldarate metabolism"
OTAU005943-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU013357-PA	7	KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14	"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism"
OTAU009067-PA	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
OTAU011975-PA	11	Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
OTAU006530-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
OTAU000556-PA	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
OTAU014022-PA	56	Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-4641257	"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Degradation of AXIN"
OTAU002201-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
OTAU013789-PA	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
OTAU015743-PA	5	KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621	"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine catabolism"
OTAU008108-PA	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
OTAU002836-PA	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
OTAU000181-PA	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
OTAU002345-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
OTAU010502-PA	3	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-525793	"Ligand-receptor interactions";"Activation of SMO";"Myogenesis"
OTAU014989-PA	9	MetaCyc: PWY-5743;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism"
OTAU013372-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU015967-PA	9	MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism"
OTAU012112-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU014657-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU011830-PA	14	Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-110320	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH"
OTAU008611-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
OTAU009286-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
OTAU002856-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU001275-PA	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
OTAU002892-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
OTAU010239-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU010366-PA	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
OTAU004941-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
OTAU008109-PA	20	Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair"
OTAU016808-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
OTAU002864-PA	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
OTAU012141-PA	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
OTAU007064-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
OTAU002959-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
OTAU002110-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
OTAU002535-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
OTAU003227-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
OTAU013364-PA	4	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs"
OTAU006029-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
OTAU005057-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
OTAU007182-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
OTAU016800-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU016568-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU001613-PA	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
OTAU002511-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
OTAU001370-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
OTAU007089-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU011733-PA	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
OTAU013465-PA	10	MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-7328	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Stachyose degradation";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
OTAU003760-PA	13	MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1	"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis"
OTAU012103-PA	11	Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418555	"PKA activation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (s) signalling events"
OTAU011230-PA	8	KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6609	"Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine salvage";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III"
OTAU001049-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
OTAU013327-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
OTAU007909-PA	3	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
OTAU013552-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
OTAU002287-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
OTAU006249-PA	11	Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210	"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER"
OTAU003199-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
OTAU011619-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
OTAU007595-PA	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates"
OTAU000151-PA	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
OTAU016135-PA	18	Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053	"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Synthesis of PA";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II"
OTAU000358-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU007554-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
OTAU002749-PA	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
OTAU004856-PA	3	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
OTAU016732-PA	2	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
OTAU002576-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
OTAU011763-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
OTAU002712-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU005192-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
OTAU006565-PA	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
OTAU001677-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
OTAU002941-PA	1	Reactome: R-HSA-420029	"Tight junction interactions"
OTAU008068-PA	1	Reactome: R-HSA-8849175	"Threonine catabolism"
OTAU013900-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU006296-PA	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
OTAU005268-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU002638-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
OTAU006247-PA	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
OTAU006046-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
OTAU002740-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
OTAU005817-PA	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
OTAU000909-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU009854-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU011797-PA	8	Reactome: R-HSA-4086398;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-5340588;Reactome: R-HSA-4608870;Reactome: R-HSA-4641263;Reactome: R-HSA-373080	"Ca2+ pathway";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"RNF mutants show enhanced WNT signaling and proliferation";"Asymmetric localization of PCP proteins";"Regulation of FZD by ubiquitination";"Class B/2 (Secretin family receptors)"
OTAU006496-PA	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
OTAU015442-PA	11	Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1	"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism"
OTAU012186-PA	26	Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-1912408;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
OTAU011414-PA	33	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-180746	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"HCMV Late Events";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein"
OTAU002635-PA	5	Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390450	"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC"
OTAU005044-PA	1	Reactome: R-HSA-71064	"Lysine catabolism"
OTAU008069-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
OTAU001324-PA	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
OTAU006725-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
OTAU016819-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU002194-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
OTAU006769-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
OTAU009985-PA	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
OTAU004570-PA	6	MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6731;MetaCyc: PWY-6737;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1	"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Starch degradation V";"Glycogen degradation II";"Starch and sucrose metabolism"
OTAU001125-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
OTAU013034-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
OTAU017351-PA	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
OTAU011391-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU000881-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
OTAU004520-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU004287-PA	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
OTAU009505-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU011773-PA	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
OTAU008696-PA	8	KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171	"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Glycolysis"
OTAU003514-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU017279-PA	8	Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism"
OTAU009298-PA	24	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase"
OTAU004328-PA	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
OTAU013785-PA	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
OTAU001593-PA	6	Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632	"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
OTAU006664-PA	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
OTAU000013-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
OTAU002924-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
OTAU003097-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
OTAU003450-PA	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629	"ECM proteoglycans";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
OTAU000277-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU000275-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU008678-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
OTAU009437-PA	7	KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483148	"Glycerophospholipid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG"
OTAU008593-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU009094-PA	10	Reactome: R-HSA-182971;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880	"EGFR downregulation";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases"
OTAU006291-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU003881-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU004485-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU005961-PA	5	Reactome: R-HSA-6807878;Reactome: R-HSA-5694530;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-9609523	"COPI-mediated anterograde transport";"Cargo concentration in the ER";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
OTAU008960-PA	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
OTAU015518-PA	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
OTAU003317-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
OTAU016391-PA	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
OTAU008022-PA	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
OTAU004560-PA	34	Reactome: R-HSA-9639288;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-159230	"Amino acids regulate mTORC1";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"RHO GTPases Activate Formins";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA"
OTAU017066-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
OTAU009462-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU001630-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
OTAU011613-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU008842-PA	4	MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20	"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism"
OTAU007476-PA	14	Reactome: R-HSA-1632852;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"Macroautophagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Intraflagellar transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
OTAU006983-PA	18	KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638	"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"(R)-cysteate degradation";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III"
OTAU006696-PA	3	Reactome: R-HSA-975871;Reactome: R-HSA-5603037;Reactome: R-HSA-168142	"MyD88 cascade initiated on plasma membrane";"IRAK4 deficiency (TLR5)";"Toll Like Receptor 10 (TLR10) Cascade"
OTAU012697-PA	4	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;Reactome: R-HSA-8849175;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)"
OTAU006641-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU004947-PA	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
OTAU001744-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
OTAU000586-PA	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
OTAU001851-PA	8	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-166208	"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"mTORC1-mediated signalling"
OTAU014428-PA	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
OTAU003757-PA	13	MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-7736;MetaCyc: PWY-7410	"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis"
OTAU004672-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU014061-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
OTAU001314-PA	27	Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-4615885	"HCMV Early Events";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins"
OTAU010598-PA	5	Reactome: R-HSA-446199;Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;MetaCyc: PWY-6129	"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
OTAU001535-PA	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
OTAU003413-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
OTAU000796-PA	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
OTAU003933-PA	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
OTAU005048-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
OTAU006795-PA	15	Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571	"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)"
OTAU011215-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
OTAU005179-PA	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
OTAU000365-PA	18	Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"mTORC1-mediated signalling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs"
OTAU013422-PA	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
OTAU016554-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU005562-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
OTAU008534-PA	33	Reactome: R-HSA-69202;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-73776;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-427413	"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression"
OTAU009196-PA	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
OTAU007589-PA	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
OTAU002049-PA	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
OTAU001566-PA	5	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-983231	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production"
OTAU016640-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
OTAU006798-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
OTAU002654-PA	2	Reactome: R-HSA-418594;Reactome: R-HSA-419771	"G alpha (i) signalling events";"Opsins"
OTAU001978-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
OTAU003267-PA	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
OTAU014100-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
OTAU003301-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU008370-PA	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
OTAU002982-PA	5	Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-918233	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway"
OTAU017045-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
OTAU008740-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
OTAU004406-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
OTAU015843-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
OTAU000614-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
OTAU009877-PA	7	Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922	"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium"
OTAU004940-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
OTAU009695-PA	33	Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-159236	"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
OTAU015951-PA	6	MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-4381	"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)"
OTAU006814-PA	11	Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)"
OTAU011052-PA	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
OTAU005860-PA	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
OTAU001707-PA	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
OTAU006649-PA	3	Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response"
OTAU002580-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
OTAU009145-PA	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
OTAU003418-PA	8	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins"
OTAU002186-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
OTAU012825-PA	19	Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497	"Scavenging by Class F Receptors";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"LDL clearance";"Chylomicron clearance";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Chylomicron assembly";"Post-translational protein phosphorylation";"LDL remodeling";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Chylomicron remodeling";"Scavenging by Class H Receptors"
OTAU006286-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU013342-PA	33	Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-5578749	"SUMOylation of SUMOylation proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"HCMV Late Events";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs"
OTAU010526-PA	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
OTAU001837-PA	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
OTAU004377-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
OTAU005611-PA	4	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
OTAU007365-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU012326-PA	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
OTAU009337-PA	6	Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-8951664;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-3214841	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines"
OTAU015330-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
OTAU008619-PA	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
OTAU016309-PA	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
OTAU002086-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
OTAU004715-PA	4	KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-212300	"Cysteine and methionine metabolism";"DNA methylation";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA"
OTAU003983-PA	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
OTAU015490-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU005749-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
OTAU008599-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
OTAU001973-PA	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
OTAU004993-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
OTAU009853-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
OTAU004319-PA	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
OTAU013427-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
OTAU006375-PA	16	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
OTAU005616-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
OTAU010754-PA	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
OTAU017225-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
OTAU002017-PA	44	Reactome: R-HSA-9634638;Reactome: R-HSA-5675221;Reactome: R-HSA-198753;Reactome: R-HSA-456926;Reactome: R-HSA-162658;Reactome: R-HSA-2871796;Reactome: R-HSA-6811558;Reactome: R-HSA-6802948;Reactome: R-HSA-5673001;Reactome: R-HSA-5674135;Reactome: R-HSA-5654726;Reactome: R-HSA-450341;Reactome: R-HSA-5654733;Reactome: R-HSA-5654732;Reactome: R-HSA-2559582;Reactome: R-HSA-2559585;Reactome: R-HSA-8943724;Reactome: R-HSA-9627069;Reactome: R-HSA-8939211;Reactome: R-HSA-6802952;Reactome: R-HSA-879415;Reactome: R-HSA-9635465;KEGG: 04150+2.7.11.24;Reactome: R-HSA-6802946;Reactome: R-HSA-1295596;Reactome: R-HSA-2029482;Reactome: R-HSA-9649948;Reactome: R-HSA-982772;Reactome: R-HSA-375165;Reactome: R-HSA-445144;Reactome: R-HSA-3371453;Reactome: R-HSA-881907;Reactome: R-HSA-5663213;Reactome: R-HSA-112409;Reactome: R-HSA-8940973;Reactome: R-HSA-5654727;Reactome: R-HSA-6802955;Reactome: R-HSA-170968;Reactome: R-HSA-444257;Reactome: R-HSA-5674499;Reactome: R-HSA-5668599;Reactome: R-HSA-202670;Reactome: R-HSA-74749;Reactome: R-HSA-2559580	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of MAPK pathway";"ERK/MAPK targets";"Thrombin signalling through proteinase activated receptors (PARs)";"Golgi Cisternae Pericentriolar Stack Reorganization";"FCERI mediated MAPK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by high-kinase activity BRAF mutants";"RAF/MAP kinase cascade";"MAP2K and MAPK activation";"Negative regulation of FGFR1 signaling";"Activation of the AP-1 family of transcription factors";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR3 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Oncogene Induced Senescence";"Regulation of PTEN gene transcription";"Regulation of the apoptosome activity";"ESR-mediated signaling";"Signaling by BRAF and RAF fusions";"Advanced glycosylation endproduct receptor signaling";"Suppression of apoptosis";"mTOR signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Spry regulation of FGF signaling";"Regulation of actin dynamics for phagocytic cup formation";"Signaling downstream of RAS mutants";"Growth hormone receptor signaling";"NCAM signaling for neurite out-growth";"Signal transduction by L1";"Regulation of HSF1-mediated heat shock response";"Gastrin-CREB signalling pathway via PKC and MAPK";"RHO GTPases Activate WASPs and WAVEs";"RAF-independent MAPK1/3 activation";"RUNX2 regulates osteoblast differentiation";"Negative regulation of FGFR2 signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Frs2-mediated activation";"RSK activation";"Negative feedback regulation of MAPK pathway";"RHO GTPases Activate NADPH Oxidases";"ERKs are inactivated";"Signal attenuation";"Oxidative Stress Induced Senescence"
OTAU007411-PA	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
OTAU010826-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
OTAU017213-PA	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
OTAU016517-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
OTAU003142-PA	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"Cis-zeatin biosynthesis"
OTAU006391-PA	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
OTAU014445-PA	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826	"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis"
OTAU005751-PA	9	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape"
OTAU013379-PA	13	MetaCyc: PWY-7220;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
OTAU015669-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
OTAU012989-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
OTAU010277-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
OTAU006198-PA	2	Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"